etoposide has been researched along with morphine in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.17) | 18.2507 |
| 2000's | 7 (29.17) | 29.6817 |
| 2010's | 16 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fischer, H; Huwyler, J; Poli, S; Schwab, D; Tabatabaei, A | 1 |
| Thakker, DR; Troutman, MD | 1 |
| Chang, TK; Ensom, MH; Kiang, TK | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Béliveau, R; Castaigne, JP; Ché, C; Currie, JC; Demeule, M; Lacoste, MC; Régina, A; Thiot, C; Yang, G | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Burghouts, JT; Haaxma-Reiche, H; Postmus, PE; van der Graaf, WT | 1 |
| Elmquist, WF; Sawchuk, RJ | 1 |
| Fujita-Hamabe, W; Kishioka, S; Kobori, T; Nakamoto, K; Nawa, A; Nishida, M; Tokuyama, S | 1 |
| Fujita-Hamabe, W; Harada, S; Kobayashi, M; Kobori, T; Nakamoto, K; Tokuyama, S | 1 |
| Harada, S; Kobori, T; Nakamoto, K; Tokuyama, S | 4 |
| Iwanaga, K; Kakemi, M; Minamida, M; Miyazaki, M; Nishimura, C | 1 |
| Iwanaga, K; Kakemi, M; Kawase, T; Kitamura, T; Miyazaki, M; Nishimura, C | 1 |
5 review(s) available for etoposide and morphine
| Article | Year |
|---|---|
UDP-glucuronosyltransferases and clinical drug-drug interactions.
Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic | 2005 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Microdialysis in the study of drug transporters in the CNS.
Topics: Animals; Biological Transport; Brain; Colchicine; Etoposide; Humans; Microdialysis; Morphine; Probenecid; Rhodamines; Zidovudine | 2000 |
[Effect of repeated oral treatment with etoposide on the expression of intestinal P-glycoprotein and oral morphine analgesia].
Topics: Administration, Oral; Analgesia; ATP Binding Cassette Transporter, Subfamily B; Etoposide; Humans; Intestinal Mucosa; Intestines; Morphine | 2014 |
[Role of Scaffold Proteins in Functional Alteration of Small Intestinal P-glycoprotein by Anti-cancer Drugs].
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytoskeletal Proteins; Drug Interactions; Etoposide; Humans; Intestine, Small; Male; Membrane Proteins; Mice, Inbred Strains; Morphine; Pain; rhoA GTP-Binding Protein | 2015 |
19 other study(ies) available for etoposide and morphine
| Article | Year |
|---|---|
Comparison of in vitro P-glycoprotein screening assays: recommendations for their use in drug discovery.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cells, Cultured; Drug Evaluation, Preclinical; Fluoresceins; Fluorescent Dyes; Humans; Indicators and Reagents; Mice; Models, Molecular; Rhodamines; Species Specificity; Swine | 2003 |
Novel experimental parameters to quantify the modulation of absorptive and secretory transport of compounds by P-glycoprotein in cell culture models of intestinal epithelium.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blotting, Western; Cells, Cultured; Diffusion; Humans; Intestinal Absorption; Intestinal Mucosa; Models, Biological; Permeability; Pharmaceutical Preparations; Pharmacokinetics | 2003 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
New Angiopep-modified doxorubicin (ANG1007) and etoposide (ANG1009) chemotherapeutics with increased brain penetration.
Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Blood-Brain Barrier; Brain; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Doxorubicin; Etoposide; Female; Humans; Inhibitory Concentration 50; Kinetics; Male; Mice; Peptides | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Teniposide for meningeal carcinomatosis of small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carboplatin; Carcinoma, Small Cell; Cyclophosphamide; Dexamethasone; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Immunologic Factors; Injections, Spinal; Interferon-gamma; Lung Neoplasms; Meningeal Neoplasms; Middle Aged; Morphine; Teniposide; Vincristine | 1993 |
Etoposide modulates the effects of oral morphine analgesia by targeting the intestinal P-glycoprotein.
Topics: Administration, Oral; Analgesics, Opioid; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cyclosporine; Disease Models, Animal; Drug Administration Schedule; Drug Interactions; Etoposide; Intestinal Mucosa; Male; Mice; Morphine; Pain; Rhodamine 123; Up-Regulation | 2012 |
RhoA affects oral morphine analgesia depending on functional variation in intestinal P-glycoprotein induced by repeated etoposide treatment.
Topics: Analgesia; Analgesics, Opioid; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Etoposide; Ileum; Intestinal Mucosa; Male; Mice; Morphine; Pain; rhoA GTP-Binding Protein | 2012 |
Activation of ERM-family proteins via RhoA-ROCK signaling increases intestinal P-gp expression and leads to attenuation of oral morphine analgesia.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Analgesia; Analgesics, Opioid; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytoskeletal Proteins; Drug Interactions; Etoposide; Fluorobenzenes; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ileum; Membrane Proteins; Mice; Microfilament Proteins; Morphine; Protein Kinase Inhibitors; Pyrimidines; rho-Associated Kinases; rhoA GTP-Binding Protein; Rosuvastatin Calcium; Signal Transduction; Sulfonamides; Up-Regulation | 2013 |
Time-dependent changes in the activation of RhoA/ROCK and ERM/p-ERM in the increased expression of intestinal P-glycoprotein by repeated oral treatment with etoposide.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytoskeletal Proteins; Enzyme Activation; Etoposide; Ileum; Male; Membrane Proteins; Mice; Microfilament Proteins; Morphine; rho-Associated Kinases | 2013 |
Pharmacokinetic assessment of absorptive interaction of oral etoposide and morphine in rats.
Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Drug Interactions; Etoposide; Intestinal Absorption; Male; Morphine; Propantheline; Quinidine; Rats; Rats, Wistar | 2014 |
Pharmacokinetics and toxicity of repeated oral etoposide is altered by morphine coadministration in rats.
Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B; Bayes Theorem; Biological Availability; Etoposide; Intestinal Absorption; Intestinal Mucosa; Male; Morphine; Rats; Rats, Wistar | 2015 |