Page last updated: 2024-08-23

etoposide and hydroxyurea

etoposide has been researched along with hydroxyurea in 91 studies

Research

Studies (91)

TimeframeStudies, this research(%)All Research%
pre-19907 (7.69)18.7374
1990's33 (36.26)18.2507
2000's33 (36.26)29.6817
2010's14 (15.38)24.3611
2020's4 (4.40)2.80

Authors

AuthorsStudies
Hansch, C; Khwaja, TA; Selassie, CD1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Ekins, S; Williams, AJ; Xu, JJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Armitage, JO; Bierman, PJ; Glenn, LD; Kessinger, A; Reed, EC; Vaughan, WP1
Lihou, MG; Smith, PJ; Tomlinson, FH1
de Vries, EG; Smit, AJ; van Essen, LH1
Alexander, RB; Coffey, DS; Nelson, WG1
Covey, JM; Holm, C; Kerrigan, D; Pommier, Y1
Bolis, G; Bonazzi, C; Landoni, F; Mangili, G; Mangioni, C; Vergadoro, F; Zanaboni, F1
Ratain, MJ; Schilsky, RL; Senekjian, EK; Simon, T; Vogelzang, NJ; Wojack, BR1
Crowther, D; Gasser, AB; Scarffe, JH; Steward, WP; Wagstaff, J1
Vogelzang, NJ1
Bellamy, AS; Hill, BT1
Kato, M; Takada, S; Takayama, S1
Hendrick, A1
Beere, HM; Chapman, RS; Chresta, CM; Dive, C; Heer, S; Herberg, AA; Hickman, JA; Whetton, AD1
Aster, JC; Inhorn, RC; Roach, SA; Slapak, CA; Soiffer, R; Stone, RM; Tantravahi, R1
Armitage, JO; Bierman, PJ; Gwilt, P; Kris, E; Vaughan, WP; Vose, J1
Alexander, IE; Miller, AD; Russell, DW1
Berger, NA; Chatterjee, S; Cheng, MF1
Bayly, AC; Dive, C; Roberts, RA1
Akkoc, N; Altungoz, O; Cehreli, C; Onvural, B; Undar, B1
Kietlińska, Z; Sablińska, B; Zieliński, J1
Bauters, F; Fenaux, P; Lovi, V; Morschhauser, F; Pagniez, D; Rose, C; Wattel, E1
Aggarwal, BB; Gallati, H; Loetscher, H; Mihalik, R; Penzes, M; Pocsik, E1
Berman, M; Blessing, JA; Burke, TW; Currie, J; Fowler, J; Muss, HB1
Berman, M; Blessing, JA; Currie, JL; McGehee, R; Soper, JT1
Copplestone, A; Couteaux, ME; Deconinck, E; Economopoulos, T; Fenaux, P; Foussard, C; Guerci, A; Hecquet, B; Mahé, B; Michaux, JL; Mufti, G; Oscier, D; Pegourié, B; Resegotti, L; Stoppa, AM; Voglova, V; Wattel, E1
Carella, AM; Frassoni, F1
Fujita, S; Hasegawa, A; Hasegawa, H; Hato, T; Ninomiya, H; Takada, K; Yanagisawa, K; Yasukawa, M1
Cannistra, SA; Korsmeyer, S; Strobel, T; Swanson, L1
Behar, C; Bertrand, Y; Dhooge, C; Lutz, P; Machinaud-Lacroix, F; Marguerite, F; Mazingue, F; Otten, J; Philippe, N; Plouvier, E; Rialland, X; Rubie, C; Souillet, G; Vilmer, E; Zix-Kieffer, I1
Grillot, DA; Nuñez, G; Simonian, PL1
Akiyama, Y; Furusho, K; Kataoka, A; Koishi, S; Kubota, M; Lin, YW; Sawada, M; Usami, I; Watanabe, Ki1
Azuma, E; Higashigawa, M; Hirayama, M; Hori, H; Ido, M; Kawasaki, H; Sakurai, M1
Akiyama, Y; Furusho, K; Kataoka, A; Kitoh, T; Koishi, S; Kubota, M; Lin, YW; Sawada, M; Usami, I; Watanabe, K1
Armstrong, MJ; Bradt, CI; Galloway, SM; Greenwood, SK; Hill, RB; Hilliard, CA; Johnson, TE1
Boqué, C; Grañena, A1
Fukuchi, K; Gomi, K; Nakamaki, T; Tomoyasu, S; Tsuruoka, N1
Brockstein, BE; Haraf, DJ; Humerickhouse, R; Vokes, EE1
Bagshawe, KD; Bower, M; Foskett, M; Holden, L; Newlands, ES; Rustin, GJ; Short, D1
Ohnishi, K1
Akutsu, M; Bai, L; Furukawa, Y; Ichikawa, A; Kano, Y; Kon, K; Suzuki, K; Tsunoda, S1
Anachkova, B; Gospodinov, A; Kunnev, D; Russev, G1
Collins, MK; Gutierrez del Arroyo, A; Palacios, C; Silva, A1
Goehle, S; Lamb, JR; Ludlow, C; Simon, JA1
Piwnica-Worms, H; Zhao, H1
Carella, AM1
Alfieri, E; Cirillo, S; D'Amore, R; Fiorillo, A; Greco, N; Maggi, G; Marano, I; Martone, A; Migliorati, R1
Akita, S; Akiyama, M; Anderson, KC; Eto, Y; Kanda, N; Kawano, T; Mizoguchi, H; Ohno, T; Yamada, H; Yamada, O1
Herrera, P; Jodra, MH; Laraña, JG; López, J; Navarro, JL; Odriozola, J; Pérez de Oteyza, J; Ramos, ML; Ramos, P; Roldán, E; Villalón, L; Zamora, C1
Armata, J; Balcerska, A; Bogusławska-Jaworska, J; Boruczkowski, D; Bubała, H; Chybicka, A; Cwiklińska, M; Hicke, A; Kaczmarek-Kanold, M; Kałwak, K; Kolecki, P; Kowalczyk, J; Krauze, A; Matysiak, M; Płoszyńska, A; Rokicka-Milewska, R; Sikorska-Fic, B; Sońta-Jakimczyk, D; Staszak-Kowalska, R; Tomaszewska, R; Turkiewicz, D; Wachowiak, J; Wiśniewska-Slusarz, H; Wysocki, M1
Bartolomé-González, B; Fernández-Herrera, J; García-Díez, A; Ruiz-Genao, DP; Sanz-Sánchez, T1
Arnaudeau, C; Hansen, LT; Helleday, T; Lundin, C; Mohindra, A; Schultz, N1
Blijlevens, N; de Pauw, B; Donnelly, P; Levenga, H; Shirango, H; Verweij, P1
Ju, XD; Lou, SQ; Peng, JQ; Tian, H; Wang, WG1
Belcourt, MF; Cory, JG; Lin, ZP; Sartorelli, AC1
Hirai, I; Sasaki, T; Wang, HG1
Garriott, ML; Hoffman, WP; Lee, C; Murphy, GP; Phelps, JB1
Ferrara, L; Kmiec, EB; Parekh-Olmedo, H1
Bissler, JJ; Dixon, K; Lu, L; Robison, JG1
Choi, VW; McCarty, DM; Samulski, RJ1
Cedrone, M; Chierichini, A; Diverio, D; Foà, R; Lo Coco, F; Mariani, G; Pasquini, L; Pelosi, E; Peschle, C; Riccioni, R; Rossini, A; Saulle, E; Testa, U; Vitale, A1
Attali, B; Bachelin, C; Baron-Van Evercooren, A; Chtarto, A; Girard, C; Lachapelle, F; Salvetti, A; Tenenbaum, L1
Bernardini, K; Buratti, T; Lanthaler, AJ; Mitterer, M1
Albanese, C; Brotherton, D; Montagnoli, A; Rainoldi, S; Santocanale, C; Tenca, P1
Fujita, H; Kurata, M; Maeda, A; Matsushita, A; Mori, M; Nagai, K; Nagai, Y; Takahashi, T; Tanaka, K; Tanaka, Y; Togami, K1
DeGregori, J; Marusyk, A1
Gottlieb, AB; Seidler, AM1
Belfort, P; Braga, A; Consonni, M; Delmanto, LR; Maestá, I; Michelin, OC; Rudge, MV1
Chen, ZC; Li, L; Li, QB; Xia, LH; You, Y; Zou, P1
Atkinson, HD; Colovic, M; Colovic, N; Jankovic, G; Kraguljac, N; Radojkovic, M; Stanisavljevic, D; Suvajdzic, N; Tomin, D; Vidovic, A1
Iland, HJ; Seymour, JF; Wei, A1
Bernstein, KA; Godin, SK; Herken, BW; Lee, AG; Mihalevic, MJ; Resnick, MA; Sobol, RW; Westmoreland, JW; Yu, Z; Zhang, Z1
Beyer, M; Dietrich, S; Göder, A; Heinzel, T; Kiweler, N; Krämer, OH; Linnebacher, M; Mahboobi, S; Mahendrarajah, N; Nikolova, T; Rauch, A; Reich, TR; Schäfer, C; Schneider, G; Sellmer, A; Sonnemann, J; Stojanovic, N; Tomicic, MT; Wieczorek, M1
Borg, C; Deconinck, E; Guenat, D; Merla, G; Rohrlich, PS1
Bertolini, F; Cassisa, A; Gasparin, P; Miggiano, MC1
Hieda, M; Higashiyama, S; Kikugawa, T; Maekawa, M; Miura, N; Saika, T; Taguchi, T; Watanabe, R1
Charoenprasert, K; Chinthammitr, Y; Kasyanan, H; Panoi, N; Phinyo, P; Pongudom, S; Purattanamal, J; Surawong, A; Wongyai, K1
Brownridge, PJ; Campbell, AE; Corbin, EK; Eyers, CE; Ferraz Franco, C; Jones, AR; Kalyuzhnyy, A; Perkins, ND; Perkins, S; Su, LI1
Chatziantoniou, A; Christodoulou, P; Drenios, C; Ioannou, I; Kourti, M; Zaravinos, A1

Reviews

10 review(s) available for etoposide and hydroxyurea

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Continuous infusion chemotherapy: a critical review.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1984, Volume: 2, Issue:11

    Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Cell Cycle; Cisplatin; Etoposide; Humans; Hydroxyurea; Infusions, Parenteral; Vinca Alkaloids

1984
A syndrome of lymphoblastic lymphoma, eosinophilia, and myeloid hyperplasia/malignancy associated with t(8;13)(p11;q11): description of a distinctive clinicopathologic entity.
    Blood, 1995, Apr-01, Volume: 85, Issue:7

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Carboplatin; Chromosomes, Human, Pair 13; Chromosomes, Human, Pair 8; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Eosinophilia; Etoposide; Fatal Outcome; Female; Humans; Hydroxyurea; Hyperplasia; Ifosfamide; Leukemia, Myeloid; Lymph Nodes; Male; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Pregnancy; Pregnancy Complications, Neoplastic; Remission Induction; Syndrome; Translocation, Genetic; Vincristine

1995
Coexistence of chronic neutrophilic leukemia with light chain myeloma.
    Acta haematologica, 1994, Volume: 91, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Marrow; Doxorubicin; Etoposide; Female; Humans; Hydroxyurea; Immunoglobulin kappa-Chains; Leukemia, Neutrophilic, Chronic; Middle Aged; Multiple Myeloma; Neoplasms, Multiple Primary

1994
[Autologous hematopoietic stem cell transplantation in chronic myeloid leukemia].
    Sangre, 1998, Volume: 43, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Blood Component Removal; Busulfan; Cisplatin; Combined Modality Therapy; Etoposide; Female; Fusion Proteins, bcr-abl; Graft Survival; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Hydroxyurea; Ifosfamide; Immunologic Factors; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Transplantation Conditioning; Transplantation, Autologous; Treatment Outcome

1998
Oral 5-FU alternatives for the treatment of head and neck cancer.
    Oncology (Williston Park, N.Y.), 1998, Volume: 12, Issue:10 Suppl 7

    Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Etoposide; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Neoplasm Recurrence, Local; Tegafur; Uracil

1998
[Oral antitumor drugs for hematological malignancies].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:3

    Topics: Administration, Oral; Antineoplastic Agents; Cytarabine; Etoposide; Hematologic Neoplasms; Humans; Hydroxyurea; Leukemia-Lymphoma, Adult T-Cell; Piperazines; Prodrugs; Tretinoin

1999
Fatal hemorrhagic pneumonia caused by infection due to Kytococcus sedentarius--a pathogen or passenger?
    Annals of hematology, 2004, Volume: 83, Issue:7

    Topics: Actinomycetales; Actinomycetales Infections; Acyclovir; Antineoplastic Combined Chemotherapy Protocols; Bacteremia; Bacterial Translocation; Cefepime; Cephalosporins; Clostridium Infections; Colistin; Cytarabine; Daunorubicin; Drug Therapy, Combination; Etoposide; Fatal Outcome; Hemoptysis; Humans; Hydroxyurea; Immunocompromised Host; Intestinal Mucosa; Leukemia, Myeloid, Acute; Male; Metronidazole; Middle Aged; Neutropenia; Pneumonia, Bacterial; Superinfection; Teicoplanin; Trimethoprim, Sulfamethoxazole Drug Combination

2004
Dermatomyositis induced by drug therapy: a review of case reports.
    Journal of the American Academy of Dermatology, 2008, Volume: 59, Issue:5

    Topics: Adult; Aged; Antibodies, Antinuclear; Autoimmune Diseases; Cyclophosphamide; Dermatomyositis; Etoposide; Female; Humans; Hydroxyurea; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Skin

2008
Have all-trans retinoic acid and arsenic trioxide replaced all-trans retinoic acid and anthracyclines in APL as standard of care.
    Best practice & research. Clinical haematology, 2014, Volume: 27, Issue:1

    Topics: Adult; Age Factors; Aged; Anthracyclines; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Blood Coagulation Factors; Clinical Trials as Topic; Combined Modality Therapy; Cytarabine; Etoposide; Humans; Hydroxyurea; Idarubicin; Leukemia, Promyelocytic, Acute; Maintenance Chemotherapy; Middle Aged; Mitoxantrone; Multicenter Studies as Topic; Oxides; Platelet Transfusion; Practice Guidelines as Topic; Remission Induction; Risk Assessment; Thioguanine; Treatment Outcome; Tretinoin

2014

Trials

7 trial(s) available for etoposide and hydroxyurea

ArticleYear
Hydroxyurea and etoposide: in vitro synergy and phase I clinical trial.
    Journal of the National Cancer Institute, 1988, Nov-02, Volume: 80, Issue:17

    Topics: Adult; Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Drug Evaluation; Drug Synergism; Etoposide; Female; Humans; Hydroxyurea; Leukemia L1210; Male; Mice; Middle Aged; Neoplasms; Tumor Cells, Cultured

1988
Treatment of relapsed non-Hodgkin's lymphoma with a combination of hydroxyurea, ifosfamide, and etoposide.
    Cancer treatment reports, 1985, Volume: 69, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Etoposide; Female; Humans; Hydroxyurea; Ifosfamide; Lymphoma; Male; Middle Aged; Recurrence

1985
Phase I/II study incorporating intravenous hydroxyurea into high-dose chemotherapy for patients with primary refractory or relapsed and refractory intermediate-grade and high-grade malignant lymphoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1995, Volume: 13, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; Combined Modality Therapy; Cyclophosphamide; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Hydroxyurea; Infusions, Intravenous; Lymphoma, Non-Hodgkin; Male; Middle Aged; Mouth Mucosa; Recurrence; Remission Induction; Risk Factors; Stomatitis; Survival Analysis

1995
Combination chemotherapy with hydroxyurea, dacarbazine (DTIC), and etoposide in the treatment of uterine leiomyosarcoma: a Gynecologic Oncology Group study.
    Gynecologic oncology, 1996, Volume: 61, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Etoposide; Female; Humans; Hydroxyurea; Leiomyosarcoma; Middle Aged; Survival Analysis; Treatment Outcome; Uterine Neoplasms

1996
Phase II trial of hydroxyurea, dacarbazine (DTIC), and etoposide (VP-16) in mixed mesodermal tumors of the uterus: a Gynecologic Oncology Group study.
    Gynecologic oncology, 1996, Volume: 61, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Disease Progression; Etoposide; Female; Humans; Hydroxyurea; Middle Aged; Mixed Tumor, Mesodermal; Neoplasm Recurrence, Local; Treatment Outcome; Uterine Neoplasms

1996
A randomized trial of hydroxyurea versus VP16 in adult chronic myelomonocytic leukemia. Groupe Français des Myélodysplasies and European CMML Group.
    Blood, 1996, Oct-01, Volume: 88, Issue:7

    Topics: Adult; Aged; Alopecia; Blood Cell Count; Cross-Over Studies; Etoposide; Female; Humans; Hydroxyurea; Karyotyping; Leukemia, Myelomonocytic, Chronic; Life Tables; Male; Middle Aged; Prognosis; Risk Factors; Splenomegaly; Survival Analysis; Treatment Outcome

1996
Efficacy and Safety of Metronomic Chemotherapy Versus Palliative Hydroxyurea in Unfit Acute Myeloid Leukemia Patients: A Multicenter, Open-Label Randomized Controlled Trial.
    Asian Pacific journal of cancer prevention : APJCP, 2020, Jan-01, Volume: 21, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Etoposide; Female; Follow-Up Studies; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisolone; Prognosis; Survival Rate

2020

Other Studies

74 other study(ies) available for etoposide and hydroxyurea

ArticleYear
Structure-activity relationships of antineoplastic agents in multidrug resistance.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:7

    Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured

1990
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
High-dose hydroxyurea in autologous bone marrow transplantation: a promising "new" agent.
    Seminars in oncology, 1992, Volume: 19, Issue:3 Suppl 9

    Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms; Carmustine; Chemotherapy, Adjuvant; Cyclophosphamide; Drug Administration Schedule; Etoposide; Humans; Hydroxyurea; Lymphoma, Non-Hodgkin; Middle Aged; Remission Induction; Survival Rate; Thiotepa

1992
Comparison of in vitro activity of epipodophyllotoxins with other chemotherapeutic agents in human medulloblastomas.
    British journal of cancer, 1991, Volume: 64, Issue:6

    Topics: Alkylating Agents; Amsacrine; Cell Division; Cell Survival; Cross-Linking Reagents; Cytarabine; DNA Damage; DNA Topoisomerases, Type II; Drug Resistance; Etoposide; Humans; Hydroxyurea; In Vitro Techniques; Karyotyping; Medulloblastoma; Teniposide; Tumor Cells, Cultured; Vincristine

1991
Successful long-term control of idiopathic hypereosinophilic syndrome with etoposide.
    Cancer, 1991, Jun-01, Volume: 67, Issue:11

    Topics: Adult; Cardiomegaly; Eosinophilia; Etoposide; Humans; Hydroxyurea; Male; Syndrome; Thrombocytopenia

1991
Synergistic enhancement by tumor necrosis factor of in vitro cytotoxicity from chemotherapeutic drugs targeted at DNA topoisomerase II.
    Cancer research, 1987, May-01, Volume: 47, Issue:9

    Topics: Animals; Bleomycin; Cell Line; Cell Survival; Cytarabine; Dactinomycin; DNA Topoisomerases, Type II; Doxorubicin; Drug Synergism; Etoposide; Fibrosarcoma; Glycoproteins; Hydroxyurea; Mice; Recombinant Proteins; Teniposide; Tumor Necrosis Factor-alpha

1987
Differential requirement of DNA replication for the cytotoxicity of DNA topoisomerase I and II inhibitors in Chinese hamster DC3F cells.
    Cancer research, 1989, Nov-15, Volume: 49, Issue:22

    Topics: Amsacrine; Animals; Aphidicolin; Camptothecin; Cell Line; Cell Survival; Cricetinae; Cricetulus; Diterpenes; DNA Replication; Etoposide; Hydroxyurea; Kinetics; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

1989
EMA/CO regimen in high-risk gestational trophoblastic tumor (GTT).
    Gynecologic oncology, 1988, Volume: 31, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dactinomycin; Doxorubicin; Etoposide; Female; Humans; Hydroxyurea; Methotrexate; Middle Aged; Pregnancy; Pregnancy Complications, Neoplastic; Trophoblastic Neoplasms; Uterine Neoplasms; Vincristine

1988
Murine L5178Y cells resulting in altered drug sensitivities from fractionated radiation exposure in vitro.
    Journal of the National Cancer Institute, 1984, Volume: 72, Issue:2

    Topics: Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Etoposide; Fluorouracil; Hydroxyurea; Leukemia L5178; Leukemia, Experimental; Methotrexate; Mice; Vincristine

1984
Comparison of lesions induced by intra-articular injections of quinolones and compounds damaging cartilage components in rat femoral condyles.
    Journal of toxicology and environmental health, 1994, Volume: 42, Issue:1

    Topics: Administration, Oral; Animals; Bleomycin; Camptothecin; Cartilage, Articular; Chondroitin Lyases; Ciprofloxacin; Collagenases; Cycloheximide; Ethylmaleimide; Etoposide; Fluorescent Dyes; Hydroxyurea; Injections, Intra-Articular; Iodoacetates; Iodoacetic Acid; Irinotecan; Levofloxacin; Male; Ofloxacin; Papain; Rats; Rats, Sprague-Dawley; Rhodamines; Topoisomerase I Inhibitors

1994
Psychosis during interferon in eosinophilic leukaemia.
    Clinical and laboratory haematology, 1994, Volume: 16, Issue:3

    Topics: Adolescent; Adrenal Cortex Hormones; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Delusions; Diagnosis, Differential; Epirubicin; Etoposide; Fatal Outcome; Hemibody Irradiation; Humans; Hydroxyurea; Hypereosinophilic Syndrome; Immunologic Factors; Interferon-alpha; Leukemic Infiltration; Male; Palliative Care; Pruritus; Skin; Somatoform Disorders; Splenectomy; Vasculitis; Vincristine

1994
Further characterisation of the in situ terminal deoxynucleotidyl transferase (TdT) assay for the flow cytometric analysis of apoptosis in drug resistant and drug sensitive leukaemic cells.
    Cytometry, 1995, Jul-01, Volume: 20, Issue:3

    Topics: Abelson murine leukemia virus; Antineoplastic Agents; Apoptosis; Cell Nucleus; DNA Damage; DNA Nucleotidylexotransferase; DNA, Neoplasm; Drug Resistance, Neoplasm; Etoposide; Flow Cytometry; HL-60 Cells; Humans; Hydroxyurea; Leukemia; Melphalan; Oncogene Proteins v-abl; Protein-Tyrosine Kinases; Recombinant Proteins; Tumor Cells, Cultured

1995
DNA synthesis and topoisomerase inhibitors increase transduction by adeno-associated virus vectors.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Jun-06, Volume: 92, Issue:12

    Topics: Aphidicolin; Cell Division; Cell Line; Dependovirus; DNA; Etoposide; Genetic Vectors; Humans; Hydroxyurea; Topoisomerase I Inhibitors; Transformation, Genetic

1995
Schedule-dependent cytotoxicity of topotecan alone and in combination chemotherapy regimens.
    Oncology research, 1994, Volume: 6, Issue:6

    Topics: Alkylating Agents; Animals; Antineoplastic Combined Chemotherapy Protocols; Aphidicolin; Camptothecin; Carmustine; Cell Cycle; Cell Death; Cell Line; Cisplatin; Cricetinae; Cricetulus; DNA Damage; DNA Repair; DNA, Neoplasm; Doxorubicin; Drug Synergism; Etoposide; Fibroblasts; Hydroxyurea; Lung; Melphalan; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Topotecan

1994
Suppression of liver cell apoptosis in vitro by the non-genotoxic hepatocarcinogen and peroxisome proliferator nafenopin.
    The Journal of cell biology, 1994, Volume: 125, Issue:1

    Topics: Animals; Apoptosis; Cells, Cultured; DNA Damage; Etoposide; Hydroxyurea; In Vitro Techniques; Liver; Liver Neoplasms, Experimental; Male; Nafenopin; Transforming Growth Factor beta

1994
Chemotherapy combined with surgery in the treatment of gestational trophoblastic disease (GTD).
    European journal of gynaecological oncology, 1993, Volume: 14 Suppl

    Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Choriocarcinoma; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Resistance; Etoposide; Female; Humans; Hydatidiform Mole; Hydroxyurea; Hysterectomy; Lung Neoplasms; Methotrexate; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Pregnancy; Salvage Therapy; Thoracotomy; Treatment Outcome; Trophoblastic Neoplasms; Uterine Hemorrhage; Uterine Neoplasms; Vincristine

1993
Glomerular injury in chronic myelomonocytic leukemia.
    Leukemia & lymphoma, 1995, Volume: 18, Issue:5-6

    Topics: Aged; Amyloidosis; Etoposide; Female; Humans; Hydroxyurea; Kidney Diseases; Kidney Glomerulus; Leukemia, Myelomonocytic, Chronic; Male; Middle Aged

1995
Effect of cell cycle on the regulation of the cell surface and secreted forms of type I and type II human tumor necrosis factor receptors.
    Journal of cellular biochemistry, 1995, Volume: 59, Issue:3

    Topics: Cell Cycle; Demecolcine; DNA; Enzyme Inhibitors; Etoposide; G1 Phase; G2 Phase; HeLa Cells; Humans; Hydroxyurea; Leukemia, Erythroblastic, Acute; Lymphoma, Large B-Cell, Diffuse; Mitosis; Nocodazole; Receptors, Tumor Necrosis Factor; S Phase; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Vinblastine

1995
ICE, mini-ICE or high-dose hydroxyurea to mobilize Philadelphia (Ph1)-negative PBPC in chronic myelogenous leukaemia.
    British journal of haematology, 1996, Volume: 95, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Hydroxyurea; Ifosfamide; Leukemia, Myelogenous, Chronic, BCR-ABL Positive

1996
[Successful treatment of combined interferon-alpha and hydroxycarbamide for chronic myelogenous leukemia following therapy for malignant lymphoma].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1996, Volume: 37, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Etoposide; Female; Humans; Hydroxyurea; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lymphoma, Follicular; Middle Aged; Neoplasms, Second Primary

1996
BAX enhances paclitaxel-induced apoptosis through a p53-independent pathway.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Nov-26, Volume: 93, Issue:24

    Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Carboplatin; Cell Cycle; Cell Line; Cell Survival; Etoposide; Female; Humans; Hydroxyurea; Immunoblotting; Kinetics; Mice; Ovarian Neoplasms; Paclitaxel; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Recombinant Proteins; Transfection; Tumor Suppressor Protein p53; Vincristine

1996
Juvenile myelomonocytic leukemia: analyses of treatment results in the EORTC Children's Leukemia Cooperative Group (CLCG).
    Bone marrow transplantation, 1996, Volume: 18, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Etoposide; Female; Follow-Up Studies; Humans; Hydroxyurea; Immunologic Factors; Infant; Interferons; Isotretinoin; Leukemia, Myelomonocytic, Acute; Life Tables; Male; Mercaptopurine; Remission Induction; Retrospective Studies; Splenectomy; Transplantation Conditioning; Treatment Outcome; Whole-Body Irradiation

1996
Bcl-2 and Bcl-XL can differentially block chemotherapy-induced cell death.
    Blood, 1997, Aug-01, Volume: 90, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-X Protein; Clone Cells; Drug Resistance, Neoplasm; Etoposide; Fluorouracil; Gamma Rays; Genes, bcl-2; Humans; Hydroxyurea; Methotrexate; Mice; Proto-Oncogene Proteins c-bcl-2; Recombinant Fusion Proteins; S Phase; Teniposide; Transfection; Vincristine

1997
Apoptosis-resistant phenotype selected by alternating exposure to camptothecin and etoposide.
    Experimental cell research, 1997, Aug-25, Volume: 235, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Arabinofuranosylcytosine Triphosphate; ATP Binding Cassette Transporter, Subfamily B, Member 1; bcl-X Protein; Calcimycin; Camptothecin; Clone Cells; Cycloheximide; Cytarabine; DNA Fragmentation; Drug Resistance, Neoplasm; Etoposide; HL-60 Cells; Humans; Hydroxyurea; Kinetics; Nucleosomes; Phenotype; Proto-Oncogene Proteins c-bcl-2; Ultraviolet Rays

1997
Salvage therapy for relapsed or refractory childhood acute lymphocytic leukemia by alternative administration a lymphoid- and myeloid-directed chemotherapeutic regimen consisting of dual modulation of ara-C, hydroxyurea, and etoposide.
    Leukemia research, 1997, Volume: 21, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Child; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dexamethasone; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Fever; Gastrointestinal Diseases; Humans; Hydrocortisone; Hydroxyurea; Leucovorin; Male; Methotrexate; Mitoxantrone; Pilot Projects; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Salvage Therapy; Treatment Outcome

1997
NADH dehydrogenase deficiency in an apoptosis-resistant mutant isolated from a human HL-60 leukemia cell line.
    Cancer research, 1997, Dec-01, Volume: 57, Issue:23

    Topics: Antineoplastic Agents; Apoptosis; Calcimycin; Camptothecin; Cell Division; Clone Cells; Cloning, Molecular; Cytarabine; Deoxyglucose; Etoposide; Glucose; HL-60 Cells; Humans; Hydroxyurea; Macromolecular Substances; Mitochondria; Mutagenesis; NADH Dehydrogenase; Transcription, Genetic; Ultraviolet Rays

1997
Fewer chromosome aberrations and earlier apoptosis induced by DNA synthesis inhibitors, a topoisomerase II inhibitor or alkylating agents in human cells with normal compared with mutant p53.
    Mutation research, 1998, Jun-05, Volume: 401, Issue:1-2

    Topics: Alkylating Agents; Antineoplastic Agents; Aphidicolin; Apoptosis; B-Lymphocytes; Cell Division; Cell Line; Chromosome Aberrations; Cytarabine; DNA Replication; Etoposide; Humans; Hydroxyurea; Methotrexate; Mutagenesis; Nucleic Acid Synthesis Inhibitors; Radiation, Ionizing; Topoisomerase II Inhibitors; Tumor Suppressor Protein p53

1998
DNA damage induces p21 protein expression by inhibiting ubiquitination in ML-1 cells.
    Biochimica et biophysica acta, 1998, Sep-16, Volume: 1404, Issue:3

    Topics: Acetylcysteine; Cell Nucleus; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cysteine Proteinase Inhibitors; Cytarabine; Deferoxamine; DNA Damage; Etoposide; Gene Expression Regulation; Hydroxyurea; Polyribosomes; RNA, Messenger; Tumor Cells, Cultured; Ubiquitins

1998
Chemotherapy for gestational trophoblastic tumours hastens menopause by 3 years.
    European journal of cancer (Oxford, England : 1990), 1998, Volume: 34, Issue:8

    Topics: Adult; Antineoplastic Agents; Choriocarcinoma; Dactinomycin; Etoposide; Female; Follow-Up Studies; Humans; Hydroxyurea; Leucovorin; Menopause, Premature; Mercaptopurine; Methotrexate; Middle Aged; Pregnancy; Retrospective Studies; Risk Factors; Trophoblastic Neoplasms

1998
In vitro cytotoxic effects of fludarabine (2-F-ara-A) in combination with commonly used antileukemic agents by isobologram analysis.
    Leukemia, 2000, Volume: 14, Issue:3

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Cell Survival; Cyclophosphamide; Cytarabine; Dose-Response Relationship, Drug; Doxorubicin; Drug Screening Assays, Antitumor; Drug Synergism; Etoposide; Humans; Hydroxyurea; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Methotrexate; Neoplastic Stem Cells; Tumor Cells, Cultured; Vidarabine; Vidarabine Phosphate; Vincristine

2000
Regulation of DNA synthesis by the higher-order chromatin structure.
    DNA and cell biology, 2000, Volume: 19, Issue:5

    Topics: Animals; Cell Nucleus; Cell-Free System; Chromatin; Cisplatin; DNA; DNA Replication; Etoposide; Hydroxyurea; Mice; Nucleic Acid Conformation; Nucleic Acid Synthesis Inhibitors; Tumor Cells, Cultured

2000
The role of p53 in death of IL-3-dependent cells in response to cytotoxic drugs.
    Oncogene, 2000, Jul-20, Volume: 19, Issue:31

    Topics: Animals; Antineoplastic Agents; Apoptosis; Bleomycin; Bone Marrow Cells; Cells, Cultured; Cisplatin; Colony-Forming Units Assay; DNA Damage; DNA Replication; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Floxuridine; Genes, p53; Hematopoietic Stem Cells; Hydroxyurea; Interleukin-3; Methotrexate; Mice; Mice, Inbred C57BL; Mice, Knockout; Radiation Tolerance; Tumor Suppressor Protein p53

2000
Thymidine incorporation is highly predictive of colony formation and can be used for high-throughput screening.
    BioTechniques, 2001, Volume: 30, Issue:5

    Topics: Animals; Antineoplastic Agents; Cell Division; Cell Survival; Chickens; CHO Cells; Colonic Neoplasms; Colony-Forming Units Assay; Cricetinae; Drug Screening Assays, Antitumor; Etoposide; Humans; Hydroxyurea; Kidney Neoplasms; Lung Neoplasms; Paclitaxel; Sensitivity and Specificity; Thymidine; Tritium; Tumor Cells, Cultured

2001
ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1.
    Molecular and cellular biology, 2001, Volume: 21, Issue:13

    Topics: Adenoviridae; Amino Acid Motifs; Antineoplastic Agents; Ataxia Telangiectasia Mutated Proteins; Caffeine; Cell Cycle; Cell Cycle Proteins; Cell Line; Checkpoint Kinase 1; Cisplatin; Cytarabine; DNA Damage; Enzyme Activation; Etoposide; Genes, Reporter; Humans; Hydroxyurea; Immunoblotting; Nucleic Acid Synthesis Inhibitors; Phosphodiesterase Inhibitors; Phosphoric Monoester Hydrolases; Phosphorylation; Phosphoserine; Protein Kinases; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins

2001
Mini-ice protocol is better than high-dose hydroxyurea to mobilize Ph-negative cells in earlier phases of chronic myelogenous leukemia.
    Leukemia & lymphoma, 2001, Volume: 40, Issue:3-4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Etoposide; Humans; Hydroxyurea; Ifosfamide; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative; Treatment Outcome

2001
Shunt-related abdominal metastases in an infant with medulloblastoma: long-term remission by systemic chemotherapy and surgery.
    Journal of neuro-oncology, 2001, Volume: 52, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carmustine; Cerebellar Neoplasms; Combined Modality Therapy; Cranial Irradiation; Craniotomy; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Hydrocephalus; Hydroxyurea; Infant; Liver Neoplasms; Magnetic Resonance Imaging; Male; Medulloblastoma; Neoplasm Recurrence, Local; Pelvic Neoplasms; Peritoneal Neoplasms; Remission Induction; Ventriculoperitoneal Shunt

2001
Telomerase overexpression in K562 leukemia cells protects against apoptosis by serum deprivation and double-stranded DNA break inducing agents, but not against DNA synthesis inhibitors.
    Cancer letters, 2002, Apr-25, Volume: 178, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Culture Media, Serum-Free; Cytarabine; DNA Damage; DNA Replication; Etoposide; Humans; Hydroxyurea; K562 Cells; Nucleic Acid Synthesis Inhibitors; Telomerase; Telomere; Transfection

2002
Autologous peripheral blood progenitor cell transplantation with <2 x 10(6) CD34(+)/kg: an analysis of variables concerning mobilisation and engraftment.
    The hematology journal : the official journal of the European Haematology Association, 2000, Volume: 1, Issue:6

    Topics: Adolescent; Adult; Aged; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Caspase 14; Caspases; Cerebral Hemorrhage; Cohort Studies; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Erythropoietin; Etoposide; Female; Graft Survival; Granulocyte Colony-Stimulating Factor; Hematologic Neoplasms; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Hydroxyurea; Infections; Leukapheresis; Life Tables; Male; Middle Aged; Neoplasms; Proportional Hazards Models; Transplantation Conditioning; Transplantation, Autologous

2000
[Results of treatment of children with chronic myelogenous leukaemia (CML) obtained by the Polish Paediatric Leukaemia/Lymphoma Study Group].
    Medycyna wieku rozwojowego, 2000, Volume: 4, Issue:1 Suppl 2

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Combined Modality Therapy; Disease-Free Survival; Etoposide; Female; Humans; Hydroxyurea; Infant; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Mercaptopurine; Poland; Remission Induction; Retrospective Studies; Stem Cell Transplantation; Transplantation, Homologous; Treatment Outcome

2000
Dermatomyositis-like reaction induced by chemotherapeutical agents.
    International journal of dermatology, 2002, Volume: 41, Issue:12

    Topics: Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Cyclophosphamide; Dermatomyositis; Etoposide; Female; Humans; Hydroxyurea; Male

2002
RAD51 is involved in repair of damage associated with DNA replication in mammalian cells.
    Journal of molecular biology, 2003, May-02, Volume: 328, Issue:3

    Topics: Animals; Apoptosis; Cell Line; Cricetinae; DNA Damage; DNA Repair; DNA Replication; DNA-Binding Proteins; Dose-Response Relationship, Drug; Etoposide; Hydroxyurea; Hypoxanthine Phosphoribosyltransferase; Kinetics; Models, Genetic; Rad51 Recombinase; Recombination, Genetic; Thymidine

2003
Effect of hydroxyurea and etoposide on transduction of human bone marrow mesenchymal stem and progenitor cell by adeno-associated virus vectors.
    Acta pharmacologica Sinica, 2004, Volume: 25, Issue:2

    Topics: Bone Marrow Cells; Cells, Cultured; Dependovirus; DNA; Etoposide; Genetic Vectors; Humans; Hydroxyurea; Luciferases; Mesenchymal Stem Cells; Nucleic Acid Synthesis Inhibitors; Topoisomerase Inhibitors; Transduction, Genetic

2004
Stable suppression of the R2 subunit of ribonucleotide reductase by R2-targeted short interference RNA sensitizes p53(-/-) HCT-116 colon cancer cells to DNA-damaging agents and ribonucleotide reductase inhibitors.
    The Journal of biological chemistry, 2004, Jun-25, Volume: 279, Issue:26

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Cisplatin; Colonic Neoplasms; Deoxyribonucleotides; DNA Damage; Down-Regulation; Doxorubicin; Enzyme Inhibitors; Etoposide; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Hydroxyurea; Intracellular Signaling Peptides and Proteins; Protein Subunits; Proto-Oncogene Proteins; Pyridines; Recombinant Proteins; Ribonucleotide Reductases; RNA, Small Interfering; Thiosemicarbazones; Tumor Suppressor Protein p53; Vincristine

2004
Human hRad1 but not hRad9 protects hHus1 from ubiquitin-proteasomal degradation.
    Oncogene, 2004, Jul-01, Volume: 23, Issue:30

    Topics: Cell Cycle; Cell Cycle Proteins; Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Etoposide; Exonucleases; Gene Expression Regulation; Humans; Hydroxyurea; Leupeptins; Mimosine; Models, Biological; Multienzyme Complexes; Nucleic Acid Synthesis Inhibitors; Proteasome Endopeptidase Complex; Schizosaccharomyces pombe Proteins; Ubiquitin; Up-Regulation

2004
Relative cytotoxicity values at the lowest effective concentration for 12 positive chemicals in the in vitro micronucleus test utilizing Chinese hamster ovary cells.
    Mutation research, 2004, Jul-11, Volume: 561, Issue:1-2

    Topics: Animals; Benz(a)Anthracenes; Bleomycin; Cell Count; Cell Survival; CHO Cells; Cricetinae; Cricetulus; Cyclophosphamide; Dactinomycin; Dose-Response Relationship, Drug; Etoposide; Female; Griseofulvin; Hazardous Substances; Hydrogen Peroxide; Hydroxyurea; Methyl Methanesulfonate; Mitomycin; Phenol; Vinblastine

2004
Enhanced oligonucleotide-directed gene targeting in mammalian cells following treatment with DNA damaging agents.
    Experimental cell research, 2004, Oct-15, Volume: 300, Issue:1

    Topics: Cell Count; Cell Line; DNA; DNA Damage; DNA Repair; DNA Replication; Electroporation; Etoposide; Flow Cytometry; Gene Targeting; Humans; Hydroxyurea; Mutagenesis, Site-Directed; Mutagens; Mutation; Oligonucleotides; Recombination, Genetic; Thymidine; Up-Regulation

2004
DNA lesion-specific co-localization of the Mre11/Rad50/Nbs1 (MRN) complex and replication protein A (RPA) to repair foci.
    The Journal of biological chemistry, 2005, Apr-01, Volume: 280, Issue:13

    Topics: Acid Anhydride Hydrolases; Blotting, Western; Camptothecin; Cations; Cell Cycle Proteins; Cell Nucleus; Comet Assay; DNA; DNA Damage; DNA Repair; DNA Repair Enzymes; DNA-Binding Proteins; DNA, Single-Stranded; Etoposide; HeLa Cells; Humans; Hydroxyurea; Macromolecular Substances; Microscopy, Fluorescence; Mitomycin; Models, Biological; MRE11 Homologue Protein; Multiprotein Complexes; Nuclear Proteins; Phosphorylation; Protein Binding; Replication Protein A; Time Factors

2005
Effects of adeno-associated virus DNA hairpin structure on recombination.
    Journal of virology, 2005, Volume: 79, Issue:11

    Topics: Aphidicolin; Base Sequence; Camptothecin; Dependovirus; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA, Circular; DNA, Viral; Etoposide; Genes, Reporter; Genetic Vectors; Genome, Viral; HeLa Cells; Humans; Hydroxyurea; Nucleic Acid Conformation; Recombination, Genetic; Terminal Repeat Sequences

2005
TRAIL decoy receptors mediate resistance of acute myeloid leukemia cells to TRAIL.
    Haematologica, 2005, Volume: 90, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 8; Cell Differentiation; Cell Membrane; Cytarabine; Drug Resistance, Neoplasm; Etoposide; Female; GPI-Linked Proteins; Granulocytes; HL-60 Cells; Humans; Hydroxyurea; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Monocytes; Oncogene Proteins, Fusion; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Member 10c; Recombinant Fusion Proteins; Tretinoin; Tumor Cells, Cultured; Tumor Necrosis Factor Decoy Receptors; Tumor Stem Cell Assay; U937 Cells

2005
Efficiency of adeno-associated virus type-2 vectors in non-human primate Schwann cells.
    Neuroreport, 2005, Nov-07, Volume: 16, Issue:16

    Topics: Analysis of Variance; Animals; Cell Count; Cell Proliferation; Cell Transplantation; Cells, Cultured; Cytomegalovirus; Demyelinating Diseases; Dependovirus; Etoposide; Fibroblasts; Gene Expression Regulation; Genetic Vectors; Green Fluorescent Proteins; Hydroxyurea; Immunohistochemistry; Macaca fascicularis; Mice; Myelin Basic Protein; Nucleic Acid Synthesis Inhibitors; Promoter Regions, Genetic; Schwann Cells; Time Factors; Transduction, Genetic

2005
Monolateral renal infarction and erythromelalgia in a case of chronic myelogenous leukemia.
    American journal of hematology, 2006, Volume: 81, Issue:3

    Topics: Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Erythromelalgia; Etoposide; Female; Humans; Hydroxyurea; Imatinib Mesylate; Infarction; Interferon-alpha; Kidney; Kidney Diseases; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Piperazines; Pyrimidines; Radiography

2006
Cdc7 is an active kinase in human cancer cells undergoing replication stress.
    The Journal of biological chemistry, 2007, Jan-05, Volume: 282, Issue:1

    Topics: Apoptosis; Cell Cycle Proteins; Cell Survival; Chromatin; DNA; Etoposide; HeLa Cells; Humans; Hydroxyurea; Minichromosome Maintenance Complex Component 2; Nuclear Proteins; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Ribonucleotide Reductases; RNA Interference; RNA, Small Interfering

2007
Multiple granulocytic sarcomas in essential thrombocythemia.
    International journal of hematology, 2006, Volume: 84, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Transfusion; Chromosome Deletion; Chromosomes, Human, Pair 7; Cytarabine; Etoposide; Fatal Outcome; Female; Femoral Fractures; Femoral Neoplasms; Humans; Hydroxyurea; Middle Aged; Mitobronitol; Neoplasm Metastasis; Nitrosourea Compounds; Primary Myelofibrosis; Radiography; Sarcoma, Myeloid; Thrombocythemia, Essential

2006
Replicational stress selects for p53 mutation.
    Cell cycle (Georgetown, Tex.), 2007, Sep-01, Volume: 6, Issue:17

    Topics: Animals; Cell Proliferation; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; DNA Replication; Etoposide; Humans; Hydroxyurea; Mice; Mutation; Oncogenes; Rad51 Recombinase; Tumor Suppressor Protein p53

2007
Maternal and perinatal outcomes of first pregnancy after chemotherapy for gestational trophoblastic neoplasia in Brazilian women.
    Gynecologic oncology, 2009, Volume: 112, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brazil; Cisplatin; Cohort Studies; Cyclophosphamide; Dactinomycin; Doxorubicin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Hydroxyurea; Methotrexate; Pregnancy; Pregnancy Outcome; Retrospective Studies; Risk Factors; Vincristine

2009
A comparative study of outcomes of idarubicin- and etoposide-intensified conditioning regimens for allogeneic peripheral blood stem cell transplantation in patients with high-risk acute leukemia.
    Acta pharmacologica Sinica, 2009, Volume: 30, Issue:10

    Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Aspergillus; Busulfan; China; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Disease-Free Survival; Etoposide; Female; Graft Survival; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Hydroxyurea; Idarubicin; Immunosuppressive Agents; Leukemia; Leukemia, Myeloid, Acute; Male; Methylprednisolone; Mucositis; Pneumonia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Premedication; Retrospective Studies; Risk Factors; Semustine; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Whole-Body Irradiation

2009
Induction chemotherapy versus palliative treatment for acute myeloid leukemia in a consecutive cohort of elderly patients.
    Annals of hematology, 2012, Volume: 91, Issue:9

    Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Blood Component Transfusion; Chromosome Aberrations; Cohort Studies; Comorbidity; Cytarabine; Daunorubicin; Etoposide; Female; Follow-Up Studies; Humans; Hydroxyurea; Immunophenotyping; Kaplan-Meier Estimate; Karyotyping; Leukemia, Myeloid; Male; Palliative Care; Remission Induction; Retrospective Studies; Serbia; Treatment Outcome

2012
The Shu complex promotes error-free tolerance of alkylation-induced base excision repair products.
    Nucleic acids research, 2016, 09-30, Volume: 44, Issue:17

    Topics: Adenine; Alkylation; Camptothecin; Cisplatin; DNA Damage; DNA Polymerase beta; DNA Repair; DNA, Fungal; Epistasis, Genetic; Etoposide; Genes, Fungal; Genetic Loci; Homologous Recombination; Humans; Hydrogen Peroxide; Hydroxyurea; Methyl Methanesulfonate; Models, Biological; Mutation; Mutation Rate; Protein Binding; Radiation, Ionizing; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Ultraviolet Rays

2016
Class I histone deacetylases regulate p53/NF-κB crosstalk in cancer cells.
    Cellular signalling, 2017, Volume: 29

    Topics: Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cellular Senescence; DNA Damage; DNA, Neoplasm; Etoposide; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxyurea; Models, Biological; Mutation; Neoplasms; NF-kappa B; Signal Transduction; Tumor Suppressor Protein p53; Vidarabine

2017
DNA damage response defect in Williams-Beuren syndrome.
    International journal of molecular medicine, 2017, Volume: 39, Issue:3

    Topics: Case-Control Studies; Cell Cycle; Cell Line; Cell Proliferation; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Etoposide; Fibroblasts; Gene Knockdown Techniques; Gene Silencing; Genetic Predisposition to Disease; Histones; Humans; Hydroxyurea; RNA, Small Interfering; Williams Syndrome

2017
Skin nodules in onset of acute myeloid leukemia, a myelomonocytic variant case.
    Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2017, Volume: 152, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy; Cytarabine; Daunorubicin; Delayed Diagnosis; Etoposide; Fatal Outcome; Fatigue; Female; Fever; Humans; Hydroxyurea; Leukemia, Myelomonocytic, Acute; Leukemic Infiltration; Leukocytosis; Metrorrhagia; Middle Aged; Myoma; Neoplasms, Multiple Primary; Palliative Care; Skin; Uterine Neoplasms

2017
SPOP is essential for DNA-protein cross-link repair in prostate cancer cells: SPOP-dependent removal of topoisomerase 2A from the topoisomerase 2A-DNA cleavage complex.
    Molecular biology of the cell, 2020, 03-15, Volume: 31, Issue:6

    Topics: Cell Death; Cell Nucleus; DNA Cleavage; DNA Replication; DNA Topoisomerases, Type II; DNA, Neoplasm; Etoposide; Histones; Humans; Hydroxyurea; Male; Models, Biological; Mutation; Nuclear Proteins; Poly-ADP-Ribose Binding Proteins; Prostatic Neoplasms; Receptors, Androgen; Repressor Proteins; Topoisomerase Inhibitors

2020
Temporal modulation of the NF-κB RelA network in response to different types of DNA damage.
    The Biochemical journal, 2021, 02-12, Volume: 478, Issue:3

    Topics: Amino Acid Motifs; Amino Acid Sequence; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Chromatography, Liquid; Consensus Sequence; DNA Breaks, Double-Stranded; DNA Damage; DNA Replication; DNA, Neoplasm; Etoposide; Humans; Hydroxyurea; Osteosarcoma; Phosphorylation; Protein Interaction Maps; Protein Kinases; Protein Processing, Post-Translational; Proteomics; Tandem Mass Spectrometry; Time Factors; Transcription Factor RelA

2021
Signatures of Co-Deregulated Genes and Their Transcriptional Regulators in Kidney Cancers.
    International journal of molecular sciences, 2023, Mar-31, Volume: 24, Issue:7

    Topics: Carrier Proteins; Etoposide; Humans; Hydroxyurea; Kidney Neoplasms; Protein Serine-Threonine Kinases; Signal Transduction

2023