Page last updated: 2024-08-23

etoposide and gossypol

etoposide has been researched along with gossypol in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's3 (50.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Johnson, DE; Land, S; Miranda, MB; Oliver, CL; Shangary, S; Wang, S1
Guang, ZZ; Jiang, WQ; Li, ZM; Liu, ZC; Yang, DJ; Zhou, JM; Zhu, XF; Zhu, ZY1
Alberti, DB; Eickhoff, J; Keppen, M; Kolesar, JM; Liu, G; Marnocha, RM; Mohammed, TA; Schelman, WR; Takebe, N; Traynor, AM; Wilding, G1
Chang, HH; Chang, JY; Chen, HH; Chen, YT; Chuang, YJ; Kuo, CC; Tang, YC; Yao, JY1

Trials

1 trial(s) available for etoposide and gossypol

ArticleYear
A phase I study of AT-101 with cisplatin and etoposide in patients with advanced solid tumors with an expanded cohort in extensive-stage small cell lung cancer.
    Investigational new drugs, 2014, Volume: 32, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Etoposide; Female; Gossypol; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms

2014

Other Studies

5 other study(ies) available for etoposide and gossypol

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
(-)-Gossypol acts directly on the mitochondria to overcome Bcl-2- and Bcl-X(L)-mediated apoptosis resistance.
    Molecular cancer therapeutics, 2005, Volume: 4, Issue:1

    Topics: Apoptosis; bcl-X Protein; Cell Survival; Etoposide; Gossypol; Humans; Jurkat Cells; Mitochondria; Proto-Oncogene Proteins c-bcl-2; Transfection

2005
Synergistic cytotoxicity of Bcl-xL inhibitor, gossypol and chemotherapeutic agents in non-Hodgkin's lymphoma cells.
    Cancer biology & therapy, 2008, Volume: 7, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cyclin D; Cyclins; Cyclophosphamide; Doxorubicin; Drug Synergism; Etoposide; Gossypol; Humans; Lymphoma, Non-Hodgkin; Paclitaxel; Prednisolone; Tumor Suppressor Protein p53; Vincristine

2008
A novel NRF2/ARE inhibitor gossypol induces cytotoxicity and sensitizes chemotherapy responses in chemo-refractory cancer cells.
    Journal of food and drug analysis, 2021, 12-15, Volume: 29, Issue:4

    Topics: Antioxidant Response Elements; Cisplatin; Etoposide; Gossypol; Humans; Neoplasms; NF-E2-Related Factor 2

2021