Page last updated: 2024-08-23

etoposide and glycine

etoposide has been researched along with glycine in 15 studies

Research

Studies (15)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (20.00)	18.2507
2000's	6 (40.00)	29.6817
2010's	6 (40.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Campillo, NE; Guerra, A; Páez, JA	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
McMahon, J; Nitiss, JL; Vilalta, PM; Wu, H	1
Allan, WP; Creighton, AM; Fattman, CL; Hasinoff, BB; Kuschak, TI; Thampatty, P; Yalowich, JC	1
Komano, T; Morishima, M; Taguchi, Y; Ueda, K	1
Choi, CH; Chung, MH; Jeong, JH; Kim, HS; Kim, MS; Kweon, OS; Lee, TB; Lim, DY; Min, YD; Rha, HS; You, HJ	1
Roninson, IB; Rose, E; Ruth, A; Stein, WD	1
Hasinoff, BB; Hofland, KF; Jensen, PB; Langer, SW; Schroeder, PE; Sehested, M	1
Al-Shawi, MK; Figler, RA; Omote, H; Polar, MK	1
Faden, AI; Lea, PM; Movsesyan, VA	1
Baranek, T; Cornillet-Lefebvre, P; Eddabra, L; El Btaouri, H; Madoulet, C; Morjani, H; Wenner, T	1
Chang, Z; Cui, B; Peng, H; Wang, Y; Zhao, W	1
Advani, AS; Caimi, P; Carew, J; Carraway, H; Chan, R; Cooper, B; de Lima, M; Elson, P; Gerds, A; Hamilton, B; Kalaycio, M; Little, J; Maciejewski, J; Malek, E; Miron, A; Mukherjee, S; Nazha, A; Pink, J; Sekeres, MA; Sobecks, R; Tomlinson, B; Unger, A; Visconte, V; Wei, W	1

Trials

1 trial(s) available for etoposide and glycine

Article	Year
A Phase I/II Trial of MEC (Mitoxantrone, Etoposide, Cytarabine) in Combination with Ixazomib for Relapsed Refractory Acute Myeloid Leukemia. Clinical cancer research : an official journal of the American Association for Cancer Research, 2019, 07-15, Volume: 25, Issue:14 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Boron Compounds; Cytarabine; Drug Resistance, Neoplasm; Etoposide; Female; Glycine; Humans; Leukemia, Myeloid, Acute; Maximum Tolerated Dose; Middle Aged; Mitoxantrone; Neoplasm Recurrence, Local; Patient Safety; Remission Induction; Salvage Therapy; Treatment Outcome	2019

Article

Year

A Phase I/II Trial of MEC (Mitoxantrone, Etoposide, Cytarabine) in Combination with Ixazomib for Relapsed Refractory Acute Myeloid Leukemia.

Clinical cancer research : an official journal of the American Association for Cancer Research, 2019, 07-15, Volume: 25, Issue:14

Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Boron Compounds; Cytarabine; Drug Resistance, Neoplasm; Etoposide; Female; Glycine; Humans; Leukemia, Myeloid, Acute; Maximum Tolerated Dose; Middle Aged; Mitoxantrone; Neoplasm Recurrence, Local; Patient Safety; Remission Induction; Salvage Therapy; Treatment Outcome

2019

Other Studies

14 other study(ies) available for etoposide and glycine

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Mutations in the gyrB domain of eukaryotic topoisomerase II can lead to partially dominant resistance to etoposide and amsacrine. Molecular pharmacology, 1994, Volume: 46, Issue:4 Topics: Amino Acid Sequence; Amsacrine; Base Sequence; DNA Gyrase; DNA Topoisomerases, Type II; Drug Resistance; Etoposide; Glycine; Lysine; Molecular Sequence Data; Mutation; Oligodeoxyribonucleotides; Saccharomyces cerevisiae	1994
Characterization of a Chinese hamster ovary cell line with acquired resistance to the bisdioxopiperazine dexrazoxane (ICRF-187) catalytic inhibitor of topoisomerase II. Biochemical pharmacology, 1997, Jun-15, Volume: 53, Issue:12 Topics: Aclarubicin; Animals; CHO Cells; Cricetinae; DNA Topoisomerases, Type II; Drug Resistance; Ethylenediamines; Etoposide; Glycine; Mutation; Razoxane; Thiobarbiturates; Topoisomerase II Inhibitors; Verapamil	1997
Amino acid substitutions in the first transmembrane domain (TM1) of P-glycoprotein that alter substrate specificity. FEBS letters, 1997, Aug-11, Volume: 413, Issue:1 Topics: Alanine; Arginine; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Membrane; Cells, Cultured; Colchicine; DNA Mutational Analysis; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Etoposide; Glycine; Histidine; Humans; Immunoblotting; Isoleucine; Leucine; Substrate Specificity; Vinblastine	1997
Reactive oxygen species-specific mechanisms of drug resistance in paraquat-resistant acute myelogenous leukemia sublines. Molecules and cells, 2000, Feb-29, Volume: 10, Issue:1 Topics: Alkynes; Antineoplastic Agents; Camptothecin; Cell Survival; Cisplatin; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Glutathione Transferase; Glycine; Humans; Leukemia, Myeloid, Acute; Metallothionein; Paraquat; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Superoxide Dismutase; Tumor Cells, Cultured; Vincristine	2000
Coordinate changes in drug resistance and drug-induced conformational transitions in altered-function mutants of the multidrug transporter P-glycoprotein. Biochemistry, 2001, Apr-10, Volume: 40, Issue:14 Topics: 3T3 Cells; Amino Acid Substitution; Animals; Antibodies, Monoclonal; Antigen-Antibody Reactions; Asparagine; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line; Colchicine; Drug Resistance, Multiple; Etoposide; Genetic Vectors; Glycine; Humans; Isoleucine; Mice; Mutagenesis, Site-Directed; Protein Conformation; Transduction, Genetic; Transfection; Valine; Vinblastine	2001
Metabolism of dexrazoxane (ICRF-187) used as a rescue agent in cancer patients treated with high-dose etoposide. Cancer chemotherapy and pharmacology, 2003, Volume: 52, Issue:2 Topics: Aged; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuvant; Ethylenediamines; Etoposide; Female; Glycine; Half-Life; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Razoxane	2003
Improved energy coupling of human P-glycoprotein by the glycine 185 to valine mutation. Biochemistry, 2004, Apr-06, Volume: 43, Issue:13 Topics: Adenosine Triphosphatases; Amino Acid Substitution; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Colchicine; Cysteine; Drug Resistance, Multiple; Electron Spin Resonance Spectroscopy; Etoposide; Glycine; History, Ancient; Humans; Membrane Lipids; Mutagenesis, Site-Directed; Saccharomyces cerevisiae Proteins; Spin Labels; Substrate Specificity; Thermodynamics; Valine	2004
Neuroprotective activity of the mGluR5 antagonists MPEP and MTEP against acute excitotoxicity differs and does not reflect actions at mGluR5 receptors. British journal of pharmacology, 2005, Volume: 145, Issue:4 Topics: Animals; Apoptosis; Cell Survival; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Etoposide; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glycine; Hydrolysis; Male; Membrane Potentials; Mice; Mice, Knockout; N-Methylaspartate; Neurons; Neuroprotective Agents; Phenylacetates; Phosphatidylinositols; Pyridines; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Thiazoles	2005
Arginine 482 to glycine mutation in ABCG2/BCRP increases etoposide transport and resistance to the drug in HEK-293 cells. Oncology reports, 2012, Volume: 27, Issue:1 Topics: Antineoplastic Agents, Phytogenic; Arginine; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Drug Resistance, Neoplasm; Etoposide; Flow Cytometry; Glycine; HEK293 Cells; Humans; Neoplasm Proteins; Point Mutation; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Transfection	2012
Glycine-functionalized Fe3O4@TiO2:Er(3+),Yb(3+) nanocarrier for microwave-triggered controllable drug release and study on mechanism of loading/release process using microcalorimetry. Expert opinion on drug delivery, 2015, Volume: 12, Issue:9 Topics: Antineoplastic Agents; Delayed-Action Preparations; Drug Delivery Systems; Drug Liberation; Etoposide; Glycine; Humans; MCF-7 Cells; Microwaves; Nanoparticles; Titanium	2015