Page last updated: 2024-08-23

etoposide and genistein

etoposide has been researched along with genistein in 36 studies

Research

Studies (36)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	17 (47.22)	18.2507
2000's	12 (33.33)	29.6817
2010's	5 (13.89)	24.3611
2020's	2 (5.56)	2.80

Authors

Authors	Studies
Bacsó, Z; Cianfriglia, M; Fenyvesi, F; Goda, K; Kappelmayer, J; Lustyik, G; Nagy, H; Szabó, G; Szilasi, M	1
Austin, CA; López-Lazaro, M; Willmore, E	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P	1
Asao, N; Dan, S; Hikita, K; Kaneda, N; Kato, K; Matsuoka, K; Matsuyama, H; Motoyama, Y; Murata, T; Nakayoshi, T; Oda, A; Okunaga, H; Tanaka, H; Yamakage, Y	1
Kawada, S; Nakano, H; Yamashita, Y	1
Dreosti, IE; Jannes, M; King, RA; Record, IR	1
Niitani, H; Nishio, K; Saijo, N; Takeda, Y	1
Iwai, H; Kariya, K; Lee, E; Miura, M; Yoshinari, M	1
Corbett, AH; Elsea, SH; Osheroff, N; Westergaard, M	1
Broxterman, HJ; Eekman, CA; Kuiper, CM; Lankelma, J; Pinedo, HM; Schuurhuis, GJ; Versantvoort, CH	1
Corbett, AH; Osheroff, N; Robinson, MJ	1
Corbett, AH; Hong, D; Osheroff, N	1
McCabe, MJ; Orrenius, S	1
Ueoka, S; Yamaguchi, M	1
Burden, DA; Elsea, SH; Lomenick, JP; Osheroff, N; Westergaard, M	1
Falaschi, A; Ochem, A; Phan, TN; Tuteja, N; Tuteja, R	1
Broadbent, JL; Dreosti, IE; Head, RJ; King, RA; Record, IR; Tonkin, AL	1
Delaporte, C; Dereuddre, S; Jacquemin-Sablon, A	1
Phan, TN; Tuteja, N	1
Bonavida, B; Borsellino, N; Ciliberto, G; D'Alessandro, N; Toniatti, C; Travali, S	1
Cruz, M; Eneroth, P; Sidén, A; Vargas, VI; Yakisich, JS	1
Baudouin, C; Casagrande, F; Darbon, JM; Ducommun, B; Escalas, N; Goubin-Gramatica, F; Penary, M	1
Bodero, A; Khanna, KK; Lavin, MF; Lees-Miller, SP; Ye, R; Zhou, BB	1
Coisy, M; Concannon, P; Darbon, JM; Ducommun, B; Théard, D	1
Ding, H; Duan, W; Ju, R; Otterson, GA; Srinivasan, K; Villalona-Calero, MA; Zhu, WG	1
Aylott, M; Burman, M; Harvey, J; Lynch, A; Nicholas, E; Rees, R; Siddiqui, A; Walker, S	1
Barjesteh van Waalwijk van Doorn-Khosrovani, S; Godschalk, RW; Janssen, J; Maas, LM; Nijhuis, JG; van Schooten, FJ	1
Bandele, OJ; Osheroff, N	1
Aller, P; Calle, C; de Blas, E; Sánchez, Y	1
Abolmaali, ND; Abramyuk, AM; Tokalov, SV	1
Baechler, S; Boege, F; Christensen, MO; Kalfalah, FM; Marko, D; Mielke, C	1
Aqaqe, N; Biechonski, S; Elad, D; Gourevich, D; Grisaru, D; Jaffa, AJ; Milyavsky, M; Olender, L; Rall, M; Raz, Y; Trakhtenbrot, L; Wiesmuller, L; Yassin, M; Zipin-Roitman, A	1
Berman, C; Emmanuel, F; Goodenow, D; Richardson, C; Sahyouni, M	1

Reviews

1 review(s) available for etoposide and genistein

Article	Year
Defining functional drug-interaction domains on topoisomerase II by exploiting mechanistic differences between drug classes. Cancer chemotherapy and pharmacology, 1994, Volume: 34 Suppl Topics: Amsacrine; Animals; Anti-Infective Agents; Antineoplastic Agents; DNA; DNA Damage; DNA Topoisomerases, Type II; Etoposide; Fluoroquinolones; Genistein; Humans; Isoflavones; Models, Structural; Quinolones; Topoisomerase II Inhibitors	1994

Article

Year

Defining functional drug-interaction domains on topoisomerase II by exploiting mechanistic differences between drug classes.

Cancer chemotherapy and pharmacology, 1994, Volume: 34 Suppl

Topics: Amsacrine; Animals; Anti-Infective Agents; Antineoplastic Agents; DNA; DNA Damage; DNA Topoisomerases, Type II; Etoposide; Fluoroquinolones; Genistein; Humans; Isoflavones; Models, Structural; Quinolones; Topoisomerase II Inhibitors

1994

Other Studies

35 other study(ies) available for etoposide and genistein

Article	Year
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies. Biochemical and biophysical research communications, 2004, Mar-19, Volume: 315, Issue:4 Topics: Adenosine Triphosphatases; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Calcium Channel Blockers; Cyclosporine; Detergents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Humans; Ivermectin; Mice; NIH 3T3 Cells; Substrate Specificity	2004
Cells lacking DNA topoisomerase II beta are resistant to genistein. Journal of natural products, 2007, Volume: 70, Issue:5 Topics: Animals; DNA; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Resistance, Neoplasm; Genistein; Luteolin; Mice; Molecular Structure	2007
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine. Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22 Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship	2012
(S)-Erypoegin K, an isoflavone isolated from Erythrina poeppigiana, is a novel inhibitor of topoisomerase IIα: Induction of G2 phase arrest in human gastric cancer cells. Bioorganic & medicinal chemistry, 2021, 01-15, Volume: 30 Topics: Antineoplastic Agents, Phytogenic; Cell Proliferation; Cell Survival; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Erythrina; G2 Phase Cell Cycle Checkpoints; Humans; Molecular Docking Simulation; Molecular Structure; Stomach Neoplasms; Structure-Activity Relationship; Topoisomerase II Inhibitors; Tumor Cells, Cultured	2021
Induction of mammalian topoisomerase II dependent DNA cleavage by nonintercalative flavonoids, genistein and orobol. Biochemical pharmacology, 1990, Feb-15, Volume: 39, Issue:4 Topics: Amsacrine; Animals; Cattle; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA, Bacterial; Enzyme Inhibitors; Escherichia coli; Etoposide; Flavonoids; Genistein; Humans; Intercalating Agents; Isoflavones; Molecular Structure; Structure-Activity Relationship	1990
Induction of micronucleus formation in mouse splenocytes by the soy isoflavone genistein in vitro but not in vivo. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1995, Volume: 33, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Cells, Cultured; Etoposide; Female; Genistein; Glycine max; Isoflavones; Mice; Mice, Inbred C57BL; Micronuclei, Chromosome-Defective; Spleen	1995
Reversal of multidrug resistance by tyrosine-kinase inhibitors in a non-P-glycoprotein-mediated multidrug-resistant cell line. International journal of cancer, 1994, Apr-15, Volume: 57, Issue:2 Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Carrier Proteins; DNA Damage; DNA Topoisomerases, Type II; Doxorubicin; Drug Resistance; Etoposide; Gene Expression; Genistein; Humans; Isoflavones; Membrane Glycoproteins; Molecular Sequence Data; Polymerase Chain Reaction; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured	1994
Selective inhibition of dexamethasone-induced apoptosis in rat thymocytes by herbimycin A. Biochemical and biophysical research communications, 1994, Jul-15, Volume: 202, Issue:1 Topics: Animals; Apoptosis; Benzoquinones; Camptothecin; Catechols; Cells, Cultured; Dexamethasone; DNA; DNA Damage; Dose-Response Relationship, Drug; Etoposide; Genistein; Isoflavones; Kinetics; L-Lactate Dehydrogenase; Lactams, Macrocyclic; Nitriles; Nucleosomes; Protein-Tyrosine Kinases; Quinones; Rats; Rifabutin; Thymus Gland; Topoisomerase I Inhibitors; Tyrphostins	1994
Genistein modulates the decreased drug accumulation in non-P-glycoprotein mediated multidrug resistant tumour cells. British journal of cancer, 1993, Volume: 68, Issue:5 Topics: Alkaloids; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Carrier Proteins; Daunorubicin; Doxorubicin; Drug Resistance; Etoposide; Genistein; Humans; Hydrogen-Ion Concentration; Isoflavones; Lung Neoplasms; Membrane Glycoproteins; Neoplasms; Protein-Tyrosine Kinases; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured	1993
Effects of topoisomerase II-targeted drugs on enzyme-mediated DNA cleavage and ATP hydrolysis: evidence for distinct drug interaction domains on topoisomerase II. Biochemistry, 1993, Apr-13, Volume: 32, Issue:14 Topics: Adenosine Triphosphate; Amsacrine; Animals; Anti-Infective Agents; Antineoplastic Agents; Binding Sites; Cell Nucleus; DNA Topoisomerases, Type II; DNA, Bacterial; Drosophila melanogaster; Escherichia coli; Etoposide; Fluoroquinolones; Genistein; Hydrolysis; Isoflavones; Novobiocin; Plasmids; Quercetin; Quinolones; Topoisomerase II Inhibitors	1993
Exploiting mechanistic differences between drug classes to define functional drug interaction domains on topoisomerase II. Evidence that several diverse DNA cleavage-enhancing agents share a common site of action on the enzyme. The Journal of biological chemistry, 1993, Jul-05, Volume: 268, Issue:19 Topics: Amsacrine; Animals; Anti-Infective Agents; Binding Sites; Cell Line; Cell Nucleus; DNA; DNA Topoisomerases, Type II; DNA, Superhelical; Drosophila melanogaster; Drug Interactions; Etoposide; Fluoroquinolones; Genistein; Growth Inhibitors; Isoflavones; Kinetics; Novobiocin; Protein Binding; Quinolones; Structure-Activity Relationship; Topoisomerase II Inhibitors	1993
Genistein induces apoptosis in immature human thymocytes by inhibiting topoisomerase-II. Biochemical and biophysical research communications, 1993, Jul-30, Volume: 194, Issue:2 Topics: Apoptosis; Benzoquinones; Cells, Cultured; Chromatin; DNA Damage; Etoposide; Genistein; Humans; Immunophenotyping; Infant; Isoflavones; Kinetics; Lactams, Macrocyclic; Methylprednisolone; Novobiocin; Phorbol 12,13-Dibutyrate; Protein-Tyrosine Kinases; Quinones; Rifabutin; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymus Gland; Time Factors; Topoisomerase II Inhibitors	1993
Effect of apoptosis-related compounds on Ca2+ transport system in isolated rat liver nuclei. Molecular and cellular biochemistry, 1997, Volume: 166, Issue:1-2 Topics: Amsacrine; Animals; Apoptosis; Aurintricarboxylic Acid; Biological Transport, Active; Calcium; Cell Nucleus; DNA Fragmentation; Etoposide; Genistein; Isoflavones; Male; Rats; Rats, Wistar	1997
Quinolones share a common interaction domain on topoisomerase II with other DNA cleavage-enhancing antineoplastic drugs. Biochemistry, 1997, Mar-11, Volume: 36, Issue:10 Topics: Amsacrine; Animals; Anti-Infective Agents; Antineoplastic Agents; Binding Sites; CHO Cells; Ciprofloxacin; Cricetinae; DNA Topoisomerases, Type II; DNA, Superhelical; Drosophila melanogaster; Electrophoresis, Agar Gel; Enzyme Activation; Etoposide; Fluoroquinolones; Genistein; Isoflavones; Kinetics; Molecular Structure; Quinolones	1997
Inhibition of DNA unwinding and ATPase activities of human DNA helicase II by chemotherapeutic agents. Biochemical and biophysical research communications, 1997, Jul-30, Volume: 236, Issue:3 Topics: Adenosine Triphosphatases; Amsacrine; Antineoplastic Agents; Aphidicolin; Camptothecin; Dactinomycin; Daunorubicin; DNA; DNA Helicases; Ellipticines; Enzyme Inhibitors; Ethidium; Etoposide; Genistein; Humans; Isoflavones; Nogalamycin; Novobiocin; Topoisomerase I Inhibitors	1997
Genistein inhibits growth of B16 melanoma cells in vivo and in vitro and promotes differentiation in vitro. International journal of cancer, 1997, Sep-04, Volume: 72, Issue:5 Topics: Animals; Antineoplastic Agents; Cell Differentiation; Cell Division; Cytochalasin B; Dose-Response Relationship, Drug; Etoposide; Female; Genistein; Growth Inhibitors; Melanoma; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Time Factors; Tumor Cells, Cultured	1997
Role of topoisomerase II beta in the resistance of 9-OH-ellipticine-resistant Chinese hamster fibroblasts to topoisomerase II inhibitors. Cancer research, 1997, Oct-01, Volume: 57, Issue:19 Topics: Amsacrine; Animals; Cell Line; Codon; Cricetinae; Cricetulus; DNA Topoisomerases, Type II; Drug Resistance, Neoplasm; Ellipticines; Enzyme Inhibitors; Etoposide; Fibroblasts; Genistein; Isoenzymes; Lung; Topoisomerase II Inhibitors	1997
Inhibition of pea chloroplast DNA helicase unwinding and ATPase activities by DNA-interacting ligands. Biochemical and biophysical research communications, 1998, Mar-27, Volume: 244, Issue:3 Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amsacrine; Camptothecin; Chloroplasts; Dactinomycin; Daunorubicin; DNA Helicases; Ellipticines; Ethidium; Etoposide; Genistein; Hydrolysis; Intercalating Agents; Ligands; Nogalamycin; Novobiocin; Pisum sativum	1998
Blocking signaling through the Gp130 receptor chain by interleukin-6 and oncostatin M inhibits PC-3 cell growth and sensitizes the tumor cells to etoposide and cisplatin-mediated cytotoxicity. Cancer, 1999, Jan-01, Volume: 85, Issue:1 Topics: Antigens, CD; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Cisplatin; Cyclohexenes; Cytokine Receptor gp130; Drug Resistance, Neoplasm; Etoposide; Genistein; Humans; Interleukin-6; Male; Membrane Glycoproteins; Monoterpenes; Oncostatin M; Peptides; Prostatic Neoplasms; Signal Transduction; Terpenes; Tumor Cells, Cultured	1999
Early effects of protein kinase modulators on DNA synthesis in rat cerebral cortex. Experimental neurology, 1999, Volume: 159, Issue:1 Topics: Animals; Anti-Inflammatory Agents; Benzoquinones; Camptothecin; Cerebral Cortex; Dimethyl Sulfoxide; DNA Replication; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA, Superhelical; Dose-Response Relationship, Drug; Enzyme Inhibitors; Etoposide; Genistein; Lactams, Macrocyclic; Naphthalenes; Nucleic Acid Synthesis Inhibitors; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Rats; Rats, Sprague-Dawley; Rifabutin; Staurosporine; Steroids; Vanadates	1999
Distinct Chk2 activation pathways are triggered by genistein and DNA-damaging agents in human melanoma cells. The Journal of biological chemistry, 2000, May-19, Volume: 275, Issue:20 Topics: Caffeine; cdc25 Phosphatases; Cell Cycle; Cell Cycle Proteins; Cell Division; Checkpoint Kinase 2; Choroid Neoplasms; DNA Damage; Doxorubicin; Enzyme Activation; Etoposide; G2 Phase; Genistein; Humans; Melanoma; Protein Kinases; Protein Serine-Threonine Kinases; Tumor Cells, Cultured	2000
The plant isoflavenoid genistein activates p53 and Chk2 in an ATM-dependent manner. The Journal of biological chemistry, 2001, Feb-16, Volume: 276, Issue:7 Topics: Androstadienes; Ataxia Telangiectasia Mutated Proteins; Benzoquinones; Caffeine; Cell Cycle Proteins; Cell Line; Checkpoint Kinase 2; DNA Fragmentation; DNA-Binding Proteins; Enzyme Inhibitors; Etoposide; Genistein; Humans; Lactams, Macrocyclic; Mutation; Phosphorylation; Plants, Medicinal; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Quinones; Rifabutin; Topoisomerase II Inhibitors; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Wortmannin	2001
Etoposide and adriamycin but not genistein can activate the checkpoint kinase Chk2 independently of ATM/ATR. Biochemical and biophysical research communications, 2001, Dec-21, Volume: 289, Issue:5 Topics: Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line; Checkpoint Kinase 2; DNA Damage; DNA-Binding Proteins; Doxorubicin; Enzyme Activation; Enzyme Inhibitors; Etoposide; G2 Phase; Genistein; Humans; Mutagens; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Topoisomerase II Inhibitors; Tumor Suppressor Proteins	2001
P21 response to DNA damage induced by genistein and etoposide in human lung cancer cells. Biochemical and biophysical research communications, 2003, Jun-13, Volume: 305, Issue:4 Topics: Antineoplastic Agents; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA Damage; DNA-Binding Proteins; Enzyme Inhibitors; Etoposide; Genistein; Humans; Lung Neoplasms; Phosphorylation; Protein Serine-Threonine Kinases; Serine; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tumor Suppressor Proteins	2003
Investigations into the concept of a threshold for topoisomerase inhibitor-induced clastogenicity. Mutagenesis, 2003, Volume: 18, Issue:4 Topics: Animals; Anti-Infective Agents; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Ciprofloxacin; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Genistein; Lymphoma; Mice; Mutagens; Topoisomerase I Inhibitors	2003
Dietary flavonoids induce MLL translocations in primary human CD34+ cells. Carcinogenesis, 2007, Volume: 28, Issue:8 Topics: Antigens, CD34; Cells, Cultured; Dietary Supplements; DNA Breaks, Double-Stranded; Etoposide; Flavonoids; Genistein; Histone-Lysine N-Methyltransferase; Humans; Kaempferols; Leukemia; Leukocytes, Mononuclear; Myeloid-Lymphoid Leukemia Protein; Quercetin; Translocation, Genetic	2007
The efficacy of topoisomerase II-targeted anticancer agents reflects the persistence of drug-induced cleavage complexes in cells. Biochemistry, 2008, Nov-11, Volume: 47, Issue:45 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Comet Assay; DNA; DNA Damage; DNA Topoisomerases, Type II; Etoposide; Genistein; Humans; Topoisomerase II Inhibitors	2008
Modulation of arsenic trioxide-induced apoptosis by genistein and functionally related agents in U937 human leukaemia cells. Regulation by ROS and mitogen-activated protein kinases. Chemico-biological interactions, 2009, Nov-10, Volume: 182, Issue:1 Topics: Adamantane; Antineoplastic Agents; Antioxidants; Apoptosis; Arsenic Trioxide; Arsenicals; Catechin; Cell Cycle; Drug Synergism; Enzyme Activation; Estradiol; Etoposide; Genistein; HL-60 Cells; Humans; Hydroquinones; Immunoblotting; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Oxides; Protein Kinase Inhibitors; Reactive Oxygen Species; RNA, Small Interfering; U937 Cells	2009
Protection of p53 wild type cells from taxol by genistein in the combined treatment of lung cancer. Nutrition and cancer, 2010, Volume: 62, Issue:6 Topics: Antineoplastic Agents, Phytogenic; Cell Cycle; Cell Line, Tumor; Cisplatin; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Genistein; Humans; Lung Neoplasms; Paclitaxel; Tumor Suppressor Protein p53	2010
Genotoxicity of dietary, environmental and therapeutic topoisomerase II poisons is uniformly correlated to prolongation of enzyme DNA residence. Molecular nutrition & food research, 2011, Volume: 55 Suppl 1 Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; DNA; DNA Cleavage; DNA Damage; DNA Topoisomerases, Type II; Etoposide; Flavonoids; Genistein; Half-Life; Histones; Humans; Linear Models; Phenols; Polyphenols; Topoisomerase II Inhibitors	2011
Quercetin alters the DNA damage response in human hematopoietic stem and progenitor cells via TopoII- and PI3K-dependent mechanisms synergizing in leukemogenic rearrangements. International journal of cancer, 2017, 02-15, Volume: 140, Issue:4 Topics: Adult; Ascorbic Acid; Cell Culture Techniques; Cell Transformation, Neoplastic; Cells, Cultured; Colony-Forming Units Assay; DNA Damage; DNA Repair; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Etoposide; Female; Genistein; Hematopoietic Stem Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Infant; Leukemia; Maternal-Fetal Exchange; Myeloid-Lymphoid Leukemia Protein; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pregnancy; Quercetin; Signal Transduction; Topoisomerase II Inhibitors	2017
Bioflavonoids cause DNA double-strand breaks and chromosomal translocations through topoisomerase II-dependent and -independent mechanisms. Mutation research. Genetic toxicology and environmental mutagenesis, 2020, Volume: 849 Topics: Animals; Cell Line; Chromosome Breakpoints; Chromosomes, Mammalian; Dexrazoxane; DNA; DNA Breaks, Double-Stranded; DNA Repair; DNA Topoisomerases, Type II; Etoposide; Flavonoids; Genistein; Histones; Kaempferols; Luteolin; Mice; Mouse Embryonic Stem Cells; Quercetin; Topoisomerase II Inhibitors; Translocation, Genetic	2020