etoposide has been researched along with eflornithine in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (18.18) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 4 (36.36) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Bakic, M; Chan, D; Freireich, EJ; Marton, LJ; Zwelling, LA | 1 |
| Dorr, RT; Gerner, EW; Liddil, JD | 1 |
| Alm, K; Berntsson, P; Oredsson, SM | 1 |
| Alm, K; Oredsson, SM | 1 |
| Caldarera, CM; Clo, C; Fattori, M; Flamigni, F; Guarnieri, C; Mackintosh, CA; Pegg, AE; Pignatti, C; Stanic', I; Stefanelli, C; Tantini, B | 1 |
| Caldarera, CM; Facchini, A; Fattori, M; Fiumana, E; Flamigni, F; Pegg, AE; Pignatti, C; Stefanelli, C; Tantini, B | 1 |
| Bakhanashvili, M; Bonda, E; Derech-Haim, S; Kadosh, R; Rahav, G; Sredni, B; Teiblum, G | 1 |
| Ashikaga, T; Bachmann, AS; Bergendahl, G; Bond, JP; Eslin, D; Ferguson, W; Gerner, EW; Higgins, T; Hiramatsu, K; Kaplan, J; Kawakita, M; Kraveka, JM; MacArthur, RB; Mitchell, D; Moriya, SS; Neville, K; Parikh, NS; Roberts, W; Saulnier Sholler, GL; Sender, L; VanderWerff, A; Wada, RK | 1 |
1 trial(s) available for etoposide and eflornithine
| Article | Year |
|---|---|
A Phase I Trial of DFMO Targeting Polyamine Addiction in Patients with Relapsed/Refractory Neuroblastoma.
Topics: Adolescent; Child; Child, Preschool; Eflornithine; Etoposide; Female; Humans; Infant; Male; Neuroblastoma; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Phenotype; Polyamines; Recurrence; Safety; Treatment Outcome | 2015 |
10 other study(ies) available for etoposide and eflornithine
| Article | Year |
|---|---|
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Effect of polyamine depletion by alpha-difluoromethylornithine or (2R,5R)-6-heptyne-2,5-diamine on drug-induced topoisomerase II-mediated DNA cleavage and cytotoxicity in human and murine leukemia cells.
Topics: Alkynes; Amsacrine; Animals; Antineoplastic Agents; Cell Line; Cell Survival; Diamines; DNA; DNA Damage; DNA Topoisomerases, Type II; Eflornithine; Etoposide; Humans; Leukemia L1210; Leukemia, Myeloid, Acute; Mice; Ornithine Decarboxylase Inhibitors; Polyamines; Tumor Cells, Cultured | 1987 |
Modulation of etoposide cytotoxicity and DNA strand scission in L1210 and 8226 cells by polyamines.
Topics: Animals; Cell Survival; DNA Topoisomerases, Type II; DNA, Neoplasm; DNA, Single-Stranded; Eflornithine; Etoposide; Humans; Leukemia L1210; Mice; Multiple Myeloma; Nucleic Acid Conformation; Ornithine; Podophyllotoxin; Polyamines; Putrescine | 1986 |
Topoisomerase II is nonfunctional in polyamine-depleted cells.
Topics: Adenosylmethionine Decarboxylase; Amidines; Animals; Cell Cycle; Cell Division; CHO Cells; Cricetinae; DNA Damage; DNA Topoisomerases, Type II; Eflornithine; Enzyme Inhibitors; Etoposide; Flow Cytometry; Indans; Ornithine Decarboxylase Inhibitors; Polyamines; Spermine; Topoisomerase II Inhibitors | 1999 |
The organization of replicon clusters is not affected by polyamine depletion.
Topics: Amanitins; Amidines; Animals; Antibodies, Monoclonal; Aphidicolin; Bromodeoxyuridine; CHO Cells; Cricetinae; DNA Replication; Eflornithine; Etoposide; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluorescent Antibody Technique; Indans; Microscopy, Confocal; Polyamines; Replicon; S Phase | 2000 |
Caspase activation in etoposide-treated fibroblasts is correlated to ERK phosphorylation and both events are blocked by polyamine depletion.
Topics: Animals; Apoptosis; Caspase Inhibitors; Caspases; Coumarins; Eflornithine; Enzyme Activation; Enzyme Inhibitors; Etoposide; Fibroblasts; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Oligopeptides; Ornithine Decarboxylase Inhibitors; Phosphorylation; Polyamines; Putrescine; Signal Transduction | 2002 |
Polyamine depletion inhibits etoposide-induced NF-kappaB activation in transformed mouse fibroblasts.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Caspases; Cell Line, Transformed; Cell Nucleus; Coumarins; DNA; Eflornithine; Enzyme Inhibitors; Etoposide; Fibroblasts; Flavonoids; In Situ Nick-End Labeling; MAP Kinase Signaling System; Mice; NF-kappa B; Phosphorylation; Polyamines; Protein Binding; Time Factors | 2004 |
Ribonuclease activity of p53 in cytoplasm in response to various stress signals.
Topics: Cell Line, Tumor; Colorectal Neoplasms; Cytoplasm; Doxorubicin; Eflornithine; ELAV Proteins; Ethylenes; Etoposide; Exonucleases; Gamma Rays; Humans; Ornithine Decarboxylase Inhibitors; Phosphorylation; Ribonucleases; RNA; RNA Stability; Stress, Physiological; Tumor Suppressor Protein p53 | 2012 |