Page last updated: 2024-08-23

etoposide and decitabine

etoposide has been researched along with decitabine in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (37.50)29.6817
2010's10 (62.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Adachi, M; Asano, T; Fujii, H; Fukunaga, Y; Hasegawa, K; Horichi, N; Isoe, T; Nakamura, K; Ohmori, T; Otake, N1
Choi, HY; Jeon, YK; Kim, CW; Kim, H; Kim, JE; Kim, YA; Kim, YN; Park, SO; Park, SS1
Ikeda, H; Imai, K; Itoh, F; Kobayashi, T; Mita, H; Sasaki, Y; Shinomura, Y; Suzuki, H; Tokino, T; Toyota, M1
Ammerpohl, O; Fölsch, UR; Kalthoff, H; Koch, D; Müerköster, SS; Schäfer, H; Sipos, B; Tsao, MS; Werbing, V1
Karp, J1
Heo, DS; Jang, JY; Jeon, YK; Kim, CW; Kim, TM; Kim, WY; Paik, JH1
Accardi, R; Creveaux, M; Guillermier, S; Herceg, Z; Shukla, R; Siouda, M; Sylla, BS; Tommasino, M; Yue, J1
Borchardt, C; Clemens, D; Dirksen, U; Frühwald, MC; Kool, M; Unland, R1
Clozel, T; Elemento, O; Erdem, Z; Hassler, MR; Krzywinski, M; Robinson, BD; Shariat, SF; Xylinas, E; Zhuang, D1
Becker, PS; Buckley, SA; Chen, TL; Estey, EH; Halpern, AB; Hendrie, PC; Huebner, EM; Orlowski, KF; Othus, M; Percival, MM; Pogosova-Agadjanyan, EL; Scott, BL; Stirewalt, DL; Walter, RB1
Alvaro, F; Arceci, RJ; Arndt, C; Barnette, P; Boklan, J; Carpten, J; Cooper, T; Farrar, JE; Gooden, GC; Gore, L; Lee, D; Legendre, C; Liang, WS; Macy, ME; Martin, L; Meshinchi, S; Narendran, A; Pollard, J; Salhia, B; Triche, TJ; Wai, D1
Fukuda, M; Hosokawa, M; Iwakawa, S; Masuda, A; Tanaka, S; Ueda, K1

Reviews

1 review(s) available for etoposide and decitabine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for etoposide and decitabine

ArticleYear
Mitoxantrone, etoposide and cytarabine following epigenetic priming with decitabine in adults with relapsed/refractory acute myeloid leukemia or other high-grade myeloid neoplasms: a phase 1/2 study.
    Leukemia, 2017, Volume: 31, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Biomarkers; Cytarabine; Decitabine; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Neoplasm Grading; Recurrence; Treatment Outcome; Young Adult

2017
A multicenter, randomized study of decitabine as epigenetic priming with induction chemotherapy in children with AML.
    Clinical epigenetics, 2017, Volume: 9

    Topics: Adolescent; Azacitidine; Child; Child, Preschool; Cytarabine; Daunorubicin; Decitabine; DNA Methylation; Epigenesis, Genetic; Etoposide; Female; Humans; Induction Chemotherapy; Infant; Leukemia, Myeloid, Acute; Male; Promoter Regions, Genetic; Treatment Outcome

2017

Other Studies

13 other study(ies) available for etoposide and decitabine

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Altered expression of topoisomerase IIalpha contributes to cross-resistant to etoposide K562/MX2 cell line by aberrant methylation.
    British journal of cancer, 2005, Apr-25, Volume: 92, Issue:8

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Azacitidine; Blotting, Northern; Carubicin; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Resistance, Neoplasm; Etoposide; Flow Cytometry; Humans; Immunoblotting; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2005
Resistance to Fas-mediated apoptosis is restored by cycloheximide through the downregulation of cellular FLIPL in NK/T-cell lymphoma.
    Laboratory investigation; a journal of technical methods and pathology, 2005, Volume: 85, Issue:7

    Topics: Antibodies, Monoclonal; Apoptosis; Apoptosis Regulatory Proteins; Azacitidine; Calcium-Calmodulin-Dependent Protein Kinases; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspases; Cell Proliferation; Cell Survival; Cycloheximide; Death-Associated Protein Kinases; Decitabine; Down-Regulation; Enzyme Activation; Etoposide; fas Receptor; Humans; Intracellular Signaling Peptides and Proteins; Jurkat Cells; Killer Cells, Natural; Lymphoma, T-Cell, Peripheral; Protein Synthesis Inhibitors

2005
The role of T-fimbrin in the response to DNA damage: silencing of T-fimbrin by small interfering RNA sensitizes human liver cancer cells to DNA-damaging agents.
    International journal of oncology, 2005, Volume: 27, Issue:4

    Topics: Actins; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Azacitidine; Carcinogens; Cell Cycle; Cell Line, Tumor; Cell Separation; Cytoskeleton; Decitabine; DNA Damage; DNA Methylation; Etoposide; Flow Cytometry; G2 Phase; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Immunoblotting; Liver Neoplasms; Membrane Glycoproteins; Microfilament Proteins; Microscopy, Fluorescence; Protein Isoforms; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Small Interfering; Time Factors; Transfection; Ultraviolet Rays

2005
Role of myofibroblasts in innate chemoresistance of pancreatic carcinoma--epigenetic downregulation of caspases.
    International journal of cancer, 2008, Oct-15, Volume: 123, Issue:8

    Topics: Animals; Apoptosis; Azacitidine; Carcinoma, Pancreatic Ductal; Caspases; Cell Line, Tumor; Cell Nucleus; Coculture Techniques; Decitabine; Deoxycytidine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Down-Regulation; Drug Resistance, Neoplasm; Epigenesis, Genetic; Etoposide; Female; Fibroblasts; Gemcitabine; Humans; Mice; Mice, SCID; Pancreatic Neoplasms; STAT1 Transcription Factor; Transfection

2008
Future research directions for the treatment of AML.
    Clinical advances in hematology & oncology : H&O, 2008, Volume: 6, Issue:11

    Topics: Antineoplastic Agents; Azacitidine; Biomedical Research; Carbazoles; Carboplatin; Cytarabine; Daunorubicin; Decitabine; Enzyme Inhibitors; Etoposide; Flavonoids; Furans; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Piperidines; Quinolones; Staurosporine; Topotecan; Tretinoin

2008
MicroRNA-146a downregulates NFκB activity via targeting TRAF6 and functions as a tumor suppressor having strong prognostic implications in NK/T cell lymphoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2011, Jul-15, Volume: 17, Issue:14

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Apoptosis; Azacitidine; Cell Line, Tumor; Cell Proliferation; Child; Decitabine; DNA Methylation; DNA Modification Methylases; Down-Regulation; Drug Synergism; Etoposide; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Kaplan-Meier Estimate; Lymphoma, Extranodal NK-T-Cell; MicroRNAs; Middle Aged; NF-kappaB-Inducing Kinase; Prognosis; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Signal Transduction; TNF Receptor-Associated Factor 6; Treatment Outcome; Young Adult

2011
Transcriptional regulation of the human tumor suppressor DOK1 by E2F1.
    Molecular and cellular biology, 2012, Volume: 32, Issue:23

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Azacitidine; Cell Line; Cell Line, Tumor; Cell Proliferation; Chromatin Assembly and Disassembly; Decitabine; DNA Damage; DNA Methylation; DNA-Binding Proteins; E2F1 Transcription Factor; Etoposide; Gene Silencing; HEK293 Cells; Humans; Methyltransferases; Phosphoproteins; Response Elements; RNA-Binding Proteins; Transcriptional Activation

2012
Analysis of the antiproliferative effects of 3-deazaneoplanocin A in combination with standard anticancer agents in rhabdoid tumor cell lines.
    Anti-cancer drugs, 2015, Volume: 26, Issue:3

    Topics: Adenosine; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azacitidine; Cell Line, Tumor; Cell Proliferation; Decitabine; Doxorubicin; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Molecular Targeted Therapy; Polycomb Repressive Complex 2; Rhabdoid Tumor; Vorinostat

2015
An Epigenomic Approach to Improving Response to Neoadjuvant Cisplatin Chemotherapy in Bladder Cancer.
    Biomolecules, 2016, 09-02, Volume: 6, Issue:3

    Topics: Antineoplastic Agents; Azacitidine; Biomarkers, Tumor; Cell Line, Tumor; Cisplatin; Decitabine; Doxorubicin; Drug Resistance, Neoplasm; Epigenomics; Etoposide; Homeodomain Proteins; Humans; Hydroxamic Acids; Methylation; Neoadjuvant Therapy; Promoter Regions, Genetic; Urinary Bladder Neoplasms; Vinblastine; Vorinostat

2016
Monophosphorylation by deoxycytidine kinase affects apparent cellular uptake of decitabine in HCT116 colon cancer cells.
    Drug metabolism and pharmacokinetics, 2017, Volume: 32, Issue:6

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Camptothecin; Colonic Neoplasms; Cytarabine; Decitabine; Deoxycytidine; Deoxycytidine Kinase; Equilibrative Nucleoside Transporter 1; Etoposide; Gemcitabine; HCT116 Cells; Humans; Irinotecan; Phosphorylation

2017