etoposide has been researched along with cytochrome c-t in 67 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (1.49) | 18.2507 |
2000's | 52 (77.61) | 29.6817 |
2010's | 14 (20.90) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Bhalla, K; Cai, J; Ibrado, AM; Jones, DP; Kim, CN; Liu, X; Peng, TI; Wang, X; Yang, J | 1 |
Arcaro, A; Downward, J; Lemoine, NR; Lesay, A; Lopes, R; McNeish, IA; Mehmet, H; Ng, BL; Pardo, OE; Seckl, MJ; Tetley, TD; Warne, PH | 1 |
Chen, H; Farr-Jones, M; Fulton, D; Gulavita, S; Moore, R; Petruk, K; Roa, WH; Shaw, A; Th'ng, J | 1 |
Li, DW; Liu, JP; Mao, YW; Xiang, H | 1 |
Kim, ND; Park, SE; Yoo, YH | 1 |
Casares, N; Droin, N; Fromentin, A; Garrido, C; Ghiringhelli, F; Gurbuxani, S; Hamai, A; Hammann, A; Kroemer, G; Moutet, M; Parcellier, A; Pequignot, M; Schmitt, E; Solary, E | 1 |
Di Giovanni, S; Faden, AI; Liu, W; Stoica, B; Wang, G; Yakovlev, AG | 1 |
Borst, J; de Vries, E; Eldering, E; Tait, SW; Werner, AB | 1 |
Karlsson, J; Påhlman, S; Pörn-Ares, I; Øra, I | 1 |
Debatin, KM; Karawajew, L; Liu, J; Meyer, LH; Mohr, A; Stahnke, K | 1 |
Villunger, A | 1 |
Bartling, B; Lewensohn, R; Zhivotovsky, B | 1 |
Boise, LH; Cepero, E; Duckett, CS; Wilkinson, JC | 1 |
Aiuchi, T; Hori, K; Horie, M; Kajimoto, S; Masuda, Y; Nakajo, S; Nakaya, K; Shibayama-Imazu, T; Shima, G | 1 |
Eliseev, RA; Gunter, TE; Rosier, RN; Vanwinkle, B | 1 |
Abe, A; Hirai, M; Ichihara, M; Maeda, K; Murakami, H; Murohara, T; Takahashi, M; Yoshida, R | 1 |
Anderson, RL; Buzzard, K; Clemons, N; Doherty, JP; Hawkins, CJ; Steel, R | 1 |
Ernberg, IT; Fadeel, B; Hu, L; Uthaisang, W; Zhang, X | 1 |
Fadeel, B; Orrenius, S; Pervaiz, S; Sun, Y | 1 |
Debatin, KM; Fulda, S | 1 |
Gibson, SB; Henson, ES; Mendoza, FJ | 1 |
Delach, SM; Emert-Sedlak, L; Johnson, DE; Miranda, MB; Rabinovitz, A; Shangary, S | 1 |
Beurel, E; Blivet-Van Eggelpoël, MJ; Cadoret, A; Capeau, J; Desbois-Mouthon, C; Kornprobst, M | 1 |
Daniel, PT; Eberle, J; Fecker, LF; Geilen, CC; Gillissen, B; Oppermann, M | 1 |
Aleo, E; Brancolini, C; Fontanini, A; Henderson, CJ; Maestro, R; Paroni, G | 1 |
Kim, TH; Park, JH | 1 |
Ellerhorst, J; Elsamman, E; Fukumori, T; Kanayama, HO; Kasai, T; Lotan, R; Nangia-Makker, P; Oka, N; Raz, A; Shono, M; Takenaka, Y | 1 |
Kagan, VE; Kapralov, AA; Kurnikov, IV; Osipov, AN; Potapovich, MV; Stoyanovsky, DA; Tyurin, VA; Vlasova, II | 1 |
Farber, JL; Karpinich, NO; Russo, MA; Schneider, T; Tafani, M | 1 |
Basova, LV; Belikova, NA; Kagan, VE; Kapralov, AA; Kurnikov, IV; Osipov, AN; Peterson, J; Potapovich, MV; Tyurin, VA; Vladimirov, YA | 1 |
Belikova, NA; Jiang, J; Kagan, VE; Kapralov, AA; Kini, V; Kurnikov, IV; Tyurin, VA; Tyurina, YY; Vlasova, II; Yalowich, JC | 1 |
Concannon, CG; Gorman, AM; Ní Chonghaile, T; Samali, A; Szegezdi, E | 1 |
Amin, HM; Atwell, C; Drakos, E; Medeiros, LJ; Oyarzo, MP; Rassidakis, GZ | 1 |
Brunner, T; Perozzo, R; Scapozza, L; Schaffner, T; Schmid, I; Simon, HU; Yousefi, S; Ziemiecki, A | 1 |
Batra, SK; Depreux, P; Henichart, JP; Johansson, SL; Lin, MF; Mimeault, M; Moore, E; Venkatraman, G | 1 |
Kissel, CK; Röckmann, H; Schadendorf, D | 1 |
Deshmukh, M; Vaughn, AE | 1 |
Bellyei, S; Boronkai, A; Farkas, R; Gallyas, F; Gomori, E; Hocsak, E; Pozsgai, E; Sumegi, B; Szigeti, A | 1 |
Cheng, X; Hou, C; Jiang, H; Jin, Q; Qian, R; Xie, H; Zhang, S; Zhang, X; Zhou, W | 1 |
Ceballos-Cancino, G; Espinosa, M; Maldonado, V; Melendez-Zajgla, J | 1 |
Afanasyeva, EA; Bahram, F; Guzhova, IV; Komarova, EY; Larsson, LG; Margulis, BA | 1 |
Brown, JM; Ellisman, MH; Frey, TG; Green, DR; Munoz-Pinedo, C; Perkins, GA; Sun, MG; Williams, J | 1 |
An, L; Han, Y; Miao, R; Wang, Q; Yang, J | 1 |
Basova, LV; Bayir, H; Belikova, NA; Jiang, J; Kagan, VE; Kapralov, AA; Kurnikov, IV; Tyurin, VA; Tyurina, YY; Vladimirov, YA; Vlasova, II; Zhao, Q | 1 |
Almeida, A; Attia, S; Delgado-Esteban, M; Detaille, D; El-Mir, MY; Fontaine, E; Guigas, B; Leverve, X; R-Villanueva, G | 1 |
Ghafourifar, P; Parihar, A; Parihar, MS | 1 |
Cho, HJ; Jin, SM; Jung, ES; Mook-Jung, I; Shim, MY | 1 |
Beaujouin, M; Liaudet-Coopman, E | 1 |
Robertson, JD; Shawgo, ME; Shelton, SN | 2 |
Bottone, MG; Pellicciari, C; Scovassi, AI; Soldani, C; Veneroni, P | 1 |
Bhattacharya, RK; Mukherjee, S; Roy, M | 1 |
Crighton, D; Fearnhead, HO; Martin, AG; Ryan, KM; Trama, J | 1 |
Arrigo, AP; Gibert, B; Manero, F; Paul, C; Simon, S; Virot, S | 1 |
Hadjidaniel, MD; Reynolds, CP | 1 |
Bergeaud, M; Guillaume, A; Le Floch, N; Leroy, J; Mathieu, L; Mignotte, B; Rincheval, V; Vayssière, JL | 1 |
Delmas, E; Gaumer, S; Guillaume, A; Mignotte, B; Renaud, F; Rodríguez-Enfedaque, A; Vayssière, JL | 1 |
Choi, JS; Joo, SH; Lee, SK; Na, M; Oh, JI | 1 |
Ngok-Ngam, P; Satayavivad, J; Thiantanawat, A; Watcharasit, P | 1 |
Huang, Q; Zhang, SH | 1 |
Benovic, JL; Cleghorn, WM; Gurevich, EV; Gurevich, VV; Kook, S; Zhan, X | 1 |
Jung, J; Kim, HY; Kim, M; Lee, K; Maeng, J; Shin, DH | 1 |
Azad, A; Storey, A | 1 |
Fuji, R; Jiang, J; Li, G; Li, L; Liu, S; Wang, Z; Xie, M; Yin, X | 1 |
Chen, L; Cui, H; Gogvadze, V; Kruspig, B; Maximchik, P; Valter, K; Zhivotovsky, B | 1 |
Jing, YX; Qi, SN; Shi, RY; Wang, LS; Yang, YJ; Yao, J; Yuan, HQ | 1 |
Aslani, F; Bergmann, M; Bhushan, S; Elsässer, HP; Fijak, M; Fröhlich, S; Keidel, M; Klug, J; Mahavadi, P; Meinhardt, A; Schuppe, HC; Sebastian, T | 1 |
67 other study(ies) available for etoposide and cytochrome c-t
Article | Year |
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Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked.
Topics: Apoproteins; Apoptosis; Caspase 3; Caspases; Cysteine Endopeptidases; Cytochrome c Group; Cytochromes c; Cytosol; DNA Fragmentation; Enzyme Activation; Etoposide; HeLa Cells; HL-60 Cells; Humans; Intracellular Membranes; Membrane Potentials; Mitochondria; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Staurosporine; Transfection | 1997 |
Fibroblast growth factor 2-mediated translational control of IAPs blocks mitochondrial release of Smac/DIABLO and apoptosis in small cell lung cancer cells.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Small Cell; Carrier Proteins; Caspases; Cell Death; Cell Line, Tumor; Culture Media, Serum-Free; Cytochromes c; Enzyme Activation; Etoposide; Fibroblast Growth Factor 2; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 1; Mitochondria; Mitochondrial Proteins; Mitogen-Activated Protein Kinase Kinases; Nucleic Acid Synthesis Inhibitors; Protein Biosynthesis; Protein Serine-Threonine Kinases; Proteins; X-Linked Inhibitor of Apoptosis Protein | 2003 |
X-linked inhibitor regulating TRAIL-induced apoptosis in chemoresistant human primary glioblastoma cells.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Carrier Proteins; Caspase 3; Caspase 9; Caspases; Cell Line, Tumor; Cell Survival; Cisplatin; Cytochromes c; Cytosol; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Etoposide; Glioblastoma; Humans; Intracellular Signaling Peptides and Proteins; Microscopy, Confocal; Mitochondria; Mitochondrial Proteins; Proteins; Signal Transduction; Time Factors; Tumor Necrosis Factor-alpha; X-Linked Inhibitor of Apoptosis Protein | 2003 |
Human alphaA- and alphaB-crystallins bind to Bax and Bcl-X(S) to sequester their translocation during staurosporine-induced apoptosis.
Topics: alpha-Crystallin A Chain; alpha-Crystallin B Chain; Animals; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Caspases; Cells, Cultured; Cytochromes c; Cytosol; Epithelial Cells; Etoposide; Genes, bcl-2; Humans; Mitochondria; Mutation; Myocytes, Cardiac; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Rats; Sorbitol; Staurosporine | 2004 |
Acetylcholinesterase plays a pivotal role in apoptosome formation.
Topics: Acetylcholinesterase; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptotic Protease-Activating Factor 1; Caspase 9; Caspases; Cytochromes c; Enzyme Activation; Etoposide; Gene Silencing; HT29 Cells; Humans; Mitochondria; Proteins; RNA, Small Interfering; Transfection | 2004 |
Increased immunogenicity of colon cancer cells by selective depletion of cytochrome C.
Topics: Animals; Apoptosis; Cisplatin; Colonic Neoplasms; Cytochromes c; DNA, Antisense; Down-Regulation; Doxorubicin; Etoposide; HCT116 Cells; HT29 Cells; Humans; Macrophages; Mice; Rats; Staurosporine; Transfection | 2004 |
BOK and NOXA are essential mediators of p53-dependent apoptosis.
Topics: Apoptosis; bcl-2-Associated X Protein; Caspase 2; Caspase 3; Caspase 8; Caspase 9; Caspases; Cell Death; Cell Line, Tumor; Cell Survival; Cytochromes c; Cytosol; DNA Damage; Enzyme Activation; Etoposide; Humans; Immunoblotting; Microscopy, Confocal; Microscopy, Fluorescence; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; Staurosporine; Time Factors; Transfection; Tumor Suppressor Protein p53 | 2004 |
Requirement for aspartate-cleaved bid in apoptosis signaling by DNA-damaging anti-cancer regimens.
Topics: Animals; Antineoplastic Agents; Apoptosis; Aspartic Acid; BH3 Interacting Domain Death Agonist Protein; Carrier Proteins; Caspase 2; Caspase 8; Caspase 9; Caspases; Cell Line; Cytochromes c; Cytoplasm; DNA Damage; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Etoposide; Flow Cytometry; Gamma Rays; Genes, Dominant; Granzymes; Humans; Immunoblotting; Jurkat Cells; Leukemia, T-Cell; Liver; Mice; Mitochondria; Models, Biological; Mutation; Retroviridae; RNA, Small Interfering; Serine Endopeptidases; Signal Transduction; Tumor Suppressor Protein p53; Up-Regulation | 2004 |
Arsenic trioxide-induced death of neuroblastoma cells involves activation of Bax and does not require p53.
Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; bcl-2-Associated X Protein; Blotting, Western; Calpain; Carboplatin; Caspase 3; Caspases; Cell Line, Tumor; Cytochromes c; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Humans; Mutation; Neuroblastoma; Oxides; Proto-Oncogene Proteins c-bcl-2; Time Factors; Tumor Suppressor Protein p53; Vincristine | 2004 |
Identification of deficient mitochondrial signaling in apoptosis resistant leukemia cells by flow cytometric analysis of intracellular cytochrome c, caspase-3 and apoptosis.
Topics: Antibodies, Monoclonal; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cell Membrane Permeability; Cyclophosphamide; Cytochromes c; Drug Resistance, Neoplasm; Etoposide; fas Receptor; Flow Cytometry; Humans; Jurkat Cells; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Microscopy, Fluorescence; Mitochondria; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Transfection | 2004 |
When cells die II: a comprehensive evaluation of apoptosis and programmed cell death.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspase Inhibitors; Caspases; Cell Line, Transformed; Cell Transformation, Viral; Cells, Cultured; Cysteine Proteinase Inhibitors; Cytochromes c; Embryo, Mammalian; Enzyme Activation; Enzyme Inhibitors; Etoposide; Fibroblasts; Kinetics; Mitochondria; Nucleic Acid Synthesis Inhibitors; Proto-Oncogene Proteins c-bcl-2; Rats; Signal Transduction; Staurosporine; Temperature; Tumor Suppressor Protein p53 | 2004 |
Endogenously released Smac is insufficient to mediate cell death of human lung carcinoma in response to etoposide.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Carcinoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Carrier Proteins; Caspases; Cell Line, Tumor; Cell Membrane; Cytochromes c; DNA Fragmentation; Down-Regulation; Etoposide; HeLa Cells; High-Temperature Requirement A Serine Peptidase 2; Humans; Inhibitor of Apoptosis Proteins; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Membrane Potentials; Mitochondria; Mitochondrial Proteins; Peptides; Protein Transport; Proteins; RNA, Small Interfering; Serine Endopeptidases | 2004 |
Upstream regulatory role for XIAP in receptor-mediated apoptosis.
Topics: Apoptosis; Apoptosis Regulatory Proteins; bcl-X Protein; Carrier Proteins; Caspase 3; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Cell Survival; Cytochromes c; Enzyme Activation; Enzyme Inhibitors; Etoposide; fas Receptor; Humans; Intracellular Signaling Peptides and Proteins; Jurkat Cells; Membrane Potentials; Mitochondria; Mitochondrial Proteins; Nucleic Acid Synthesis Inhibitors; Proteins; Proto-Oncogene Proteins c-bcl-2; RNA Interference; X-Linked Inhibitor of Apoptosis Protein | 2004 |
Involvement of tumor necrosis factor receptor-associated protein 1 (TRAP1) in apoptosis induced by beta-hydroxyisovalerylshikonin.
Topics: Acetylcysteine; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Blotting, Northern; Blotting, Western; Cell Death; Cell Line; Cell Line, Tumor; Coloring Agents; Cytochromes c; Cytosol; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme Inhibitors; Etoposide; Gene Expression Regulation; Genetic Vectors; HL-60 Cells; HSP90 Heat-Shock Proteins; Humans; K562 Cells; Mitochondria; Naphthoquinones; Oligonucleotide Array Sequence Analysis; Plasmids; Reactive Oxygen Species; RNA, Small Interfering; Subcellular Fractions; Time Factors; Transfection | 2004 |
Diazoxide-mediated preconditioning against apoptosis involves activation of cAMP-response element-binding protein (CREB) and NFkappaB.
Topics: Apoptosis; bcl-X Protein; Blotting, Western; Calcium; Cell Membrane; Cell Nucleus; Cyclic AMP Response Element-Binding Protein; Cytochromes c; Cytosol; Decanoic Acids; Diazoxide; Etoposide; HL-60 Cells; Humans; Hydroxy Acids; Intracellular Membranes; Membrane Potentials; Microscopy, Electron; Mitochondria; Models, Biological; NF-kappa B; Oxygen; Oxygen Consumption; Peptides; Phosphorylation; Potassium Channels; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Transcription, Genetic; Vasodilator Agents | 2004 |
Biochemical and biological responses induced by coupling of Gab1 to phosphatidylinositol 3-kinase in RET-expressing cells.
Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis; Binding Sites; Cell Line, Tumor; Cell Separation; Cytochromes c; DNA, Complementary; Dose-Response Relationship, Drug; Etoposide; Flow Cytometry; Glial Cell Line-Derived Neurotrophic Factor; Glial Cell Line-Derived Neurotrophic Factor Receptors; Glutathione Transferase; Humans; Immunoblotting; Immunoprecipitation; Mice; Microscopy, Fluorescence; Mitochondria; Mitogen-Activated Protein Kinases; Models, Biological; Models, Genetic; Mutation; Nerve Growth Factors; NIH 3T3 Cells; Phosphatidylinositol 3-Kinases; Phosphoproteins; Plasmids; Polymerase Chain Reaction; Protein Binding; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Receptor Protein-Tyrosine Kinases; Retroviridae; Signal Transduction; Time Factors; Transfection | 2004 |
Hsp72 inhibits apoptosis upstream of the mitochondria and not through interactions with Apaf-1.
Topics: Animals; Apoptosis; Apoptotic Protease-Activating Factor 1; Blotting, Western; Caspase 3; Caspases; Cell Nucleus; Cell Proliferation; Cells, Cultured; Cytochromes c; Cytosol; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Etoposide; Fibroblasts; Fluorescent Dyes; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Intracellular Membranes; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Mitochondria; Proteins; Recombinant Proteins; Rhodamines; Salts; Temperature; Time Factors; Tumor Necrosis Factor-alpha; Ultraviolet Rays | 2004 |
Epstein-Barr virus-encoded latent membrane protein 1 promotes stress-induced apoptosis upstream of caspase-2-dependent mitochondrial perturbation.
Topics: Antineoplastic Agents; Apoptosis; Caspase 2; Caspases; Cisplatin; Cytochromes c; Enzyme Activation; Etoposide; HeLa Cells; Herpesvirus 4, Human; Humans; Membrane Potentials; Mitochondria; Nasopharyngeal Neoplasms; Protein Structure, Tertiary; Stress, Physiological; Transfection; Tumor Cells, Cultured; Viral Matrix Proteins | 2005 |
Plasma membrane sequestration of apoptotic protease-activating factor-1 in human B-lymphoma cells: a novel mechanism of chemoresistance.
Topics: Apoptosis; Apoptotic Protease-Activating Factor 1; Caspases; Cell Line, Tumor; Cell Membrane; Cytochromes c; Cytosol; Drug Resistance, Neoplasm; Enzyme Activation; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Lymphoma, B-Cell; Mitochondria; Protein Transport; Proteins | 2005 |
Sensitization for anticancer drug-induced apoptosis by betulinic Acid.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Betulinic Acid; Caspases; Cells, Cultured; Cisplatin; Complement Membrane Attack Complex; Complement System Proteins; Cytochromes c; Dactinomycin; Doxorubicin; Drug Synergism; Enzyme Activation; Etoposide; Fibroblasts; Glycoproteins; Humans; Membrane Potentials; Mitochondria; Mutation; Neoplasms; Paclitaxel; Pentacyclic Triterpenes; Proto-Oncogene Proteins c-bcl-2; Triterpenes; Tumor Stem Cell Assay; Tumor Suppressor Protein p53 | 2005 |
MEKK1-induced apoptosis is mediated by Smac/Diablo release from the mitochondria.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Base Sequence; Carrier Proteins; Cell Line; Cytochromes c; Etoposide; Humans; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; MAP Kinase Kinase Kinase 1; Mice; Mice, Knockout; Mitochondria; Mitochondrial Proteins; Mitogen-Activated Protein Kinase Kinases; Proteins; RNA, Small Interfering; X-Linked Inhibitor of Apoptosis Protein | 2005 |
Involvement of cathepsin D in chemotherapy-induced cytochrome c release, caspase activation, and cell death.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Caspases; Cathepsin D; Cisplatin; Cytochromes c; Cytosol; Enzyme Activation; Etoposide; Fluorouracil; HeLa Cells; Humans; Protein Transport; RNA, Small Interfering; U937 Cells | 2005 |
GSK-3beta reactivation with LY294002 sensitizes hepatoma cells to chemotherapy-induced apoptosis.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Camptothecin; Carcinoma, Hepatocellular; Caspase 3; Caspase 8; Caspases; Cell Line, Tumor; Chromones; Cytochromes c; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; Etoposide; fas Receptor; Flow Cytometry; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Morpholines; Mutation; Phosphatidylinositol 3-Kinases; Phosphorylation; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Reverse Transcriptase Polymerase Chain Reaction; Serine; Transfection; Tumor Suppressor Protein p53 | 2005 |
Caspase-independent induction of apoptosis in human melanoma cells by the proapoptotic Bcl-2-related protein Nbk / Bik.
Topics: Animals; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Caspases; Chromatin; Cytochromes c; Diphosphonates; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; fas Receptor; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; In Situ Nick-End Labeling; Injections, Subcutaneous; Melanoma; Mice; Mice, Inbred BALB C; Mice, Nude; Pamidronate; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-bcl-2; Skin; Tetracycline; Tumor Cells, Cultured | 2005 |
Caspase activation and apoptosis in response to proteasome inhibitors.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Carrier Proteins; Caspase 9; Caspases; Cell Death; Cytochromes c; Cytosol; Enzyme Activation; Enzyme Inhibitors; Etoposide; Green Fluorescent Proteins; Humans; Image Processing, Computer-Assisted; Intracellular Signaling Peptides and Proteins; Kinetics; Membrane Potentials; Microscopy, Confocal; Microscopy, Fluorescence; Mitochondria; Mitochondrial Proteins; Plasmids; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Proto-Oncogene Proteins c-bcl-2; Retroviridae; RNA, Small Interfering; Time Factors; Transfection | 2005 |
Release of cytochrome c from isolated mitochondria by etoposide.
Topics: Animals; Cell Death; Cell Line, Tumor; Cytochromes c; Etoposide; Humans; Mice; Mitochondria, Liver; Tumor Suppressor Protein p53 | 2005 |
Galectin-3 regulates mitochondrial stability and antiapoptotic function in response to anticancer drug in prostate cancer.
Topics: Apoptosis; bcl-Associated Death Protein; Caspase 3; Caspase Inhibitors; Caspases; Cell Line, Tumor; Cell Nucleus; Cisplatin; Cytochromes c; Enzyme Activation; Etoposide; Galectin 3; Humans; Male; Mitochondria; Prostatic Neoplasms; Transfection | 2006 |
Nitric oxide inhibits peroxidase activity of cytochrome c.cardiolipin complex and blocks cardiolipin oxidation.
Topics: Animals; Apoptosis; Cardiolipins; Cytochromes c; Electron Spin Resonance Spectroscopy; Etoposide; Heme; Horses; Hydrogen Peroxide; Nitric Oxide; Oxygen; Phospholipids | 2006 |
The course of etoposide-induced apoptosis in Jurkat cells lacking p53 and Bax.
Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; BH3 Interacting Domain Death Agonist Protein; Caspase Inhibitors; Caspases; Cyclosporine; Cytochromes c; DNA Damage; DNA-Binding Proteins; DNA, Neoplasm; Enzyme Activation; Etoposide; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Jurkat Cells; Mitochondria; Mitochondrial Membranes; Mitochondrial Swelling; Nuclear Proteins; Phosphorylation; Proto-Oncogene Proteins c-abl; Proto-Oncogene Proteins c-bcl-2; T-Lymphocytes; Tumor Protein p73; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2006 |
Peroxidase activity and structural transitions of cytochrome c bound to cardiolipin-containing membranes.
Topics: Acridine Orange; Animals; Binding, Competitive; Cardiolipins; Cell Membrane; Cytochromes c; Electrophoresis; Enzyme Activation; Etoposide; Fluoresceins; Horses; Hydrophobic and Hydrophilic Interactions; Lipids; Liposomes; Osmolar Concentration; Oxidation-Reduction; Peroxidase; Phosphatidylcholines; Spectrometry, Fluorescence; Structure-Activity Relationship; Time Factors; Tryptophan | 2006 |
Mechanisms of cardiolipin oxidation by cytochrome c: relevance to pro- and antiapoptotic functions of etoposide.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Azo Compounds; Cardiolipins; Cytochromes c; Electron Spin Resonance Spectroscopy; Etoposide; Free Radicals; HL-60 Cells; Humans; Nitriles; Oxidation-Reduction; Peroxides; Tyrosine | 2006 |
Dexamethasone inhibits apoptosis in C6 glioma cells through increased expression of Bcl-XL.
Topics: Animals; Antineoplastic Agents, Hormonal; Apoptosis; bcl-X Protein; Blotting, Northern; Blotting, Western; Caspase 3; Caspase 9; Caspases; Cell Line, Tumor; Cytochromes c; Dexamethasone; Enzyme Activation; Etoposide; Gene Expression; Mifepristone; Receptors, Glucocorticoid; RNA, Messenger; RNA, Small Interfering; Staurosporine; Thapsigargin | 2006 |
Intrinsic apoptotic pathway in anaplastic large cell lymphoma.
Topics: Anaplastic Lymphoma Kinase; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Caspase 3; Caspase 9; Caspases; Cell Line, Tumor; Cytochromes c; Disease-Free Survival; Doxorubicin; Enzyme Activation; Enzyme Inhibitors; Etoposide; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Lymphoma, Large B-Cell, Diffuse; Protein-Tyrosine Kinases; Receptor Protein-Tyrosine Kinases | 2006 |
Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Autophagy-Related Protein 5; Calpain; Caspases; Cytochromes c; Cytosol; Doxorubicin; Drug Resistance, Neoplasm; Enzyme Activation; Enzyme Inhibitors; Etoposide; Granulocyte-Macrophage Colony-Stimulating Factor; HeLa Cells; Humans; Microtubule-Associated Proteins; Mitochondria; Proto-Oncogene Proteins c-bcl-2; RNA, Small Interfering; Staurosporine | 2006 |
Novel combination therapy against metastatic and androgen-independent prostate cancer by using gefitinib, tamoxifen and etoposide.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Caspases; Cell Proliferation; Cells, Cultured; Ceramides; Cytochromes c; Drug Synergism; Epidermal Growth Factor; ErbB Receptors; Etoposide; Flow Cytometry; Gefitinib; Humans; Immunoenzyme Techniques; Male; Membrane Potential, Mitochondrial; Neoplasms, Hormone-Dependent; Prostate; Prostatic Neoplasms; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tamoxifen | 2007 |
The altered apoptotic pathways in cisplatin and etoposide-resistant melanoma cells are drug specific.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Caspases; Cisplatin; Cytochromes c; Drug Resistance, Neoplasm; Enzyme Activation; Etoposide; Humans; Melanoma; Poly(ADP-ribose) Polymerases; Signal Transduction; Tumor Cells, Cultured | 2006 |
Essential postmitochondrial function of p53 uncovered in DNA damage-induced apoptosis in neurons.
Topics: Animals; Apoptosis; Apoptosomes; Apoptotic Protease-Activating Factor 1; Cytochromes c; DNA Damage; Etoposide; Gene Expression Regulation; Mice; Mitochondria; Models, Biological; Nerve Growth Factor; Neurons; Protein Biosynthesis; Protein Processing, Post-Translational; RNA, Messenger; Tumor Suppressor Protein p53; X-Linked Inhibitor of Apoptosis Protein | 2007 |
Preventing apoptotic cell death by a novel small heat shock protein.
Topics: Amino Acid Sequence; Animals; Apoptosis; Caspase 3; Cytochromes c; Enzyme Activation; Etoposide; Gene Expression; Genome, Human; Heat-Shock Proteins, Small; HeLa Cells; Humans; Intracellular Signaling Peptides and Proteins; Mice; Molecular Sequence Data; NIH 3T3 Cells; Protein Processing, Post-Translational; Protein Structure, Quaternary; Protein Transport; Sequence Alignment; Sequence Homology; Temperature | 2007 |
Matrine upregulates the cell cycle protein E2F-1 and triggers apoptosis via the mitochondrial pathway in K562 cells.
Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptotic Protease-Activating Factor 1; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Cytochromes c; Dose-Response Relationship, Drug; Down-Regulation; Drug Synergism; E2F1 Transcription Factor; Enzyme Activation; Etoposide; HeLa Cells; Humans; K562 Cells; Leukemia, Erythroblastic, Acute; Matrines; Mitochondria; Protein Transport; Quinolizines; Retinoblastoma Protein; Time Factors; Tumor Suppressor Protein p53; U937 Cells; Up-Regulation | 2007 |
Regulation of mitochondrial Smac/DIABLO-selective release by survivin.
Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Caspases; Cytochromes c; Cytosol; Enzyme Activation; Etoposide; HeLa Cells; Humans; Inhibitor of Apoptosis Proteins; Intracellular Signaling Peptides and Proteins; Microtubule-Associated Proteins; Mitochondria; Mitochondrial Proteins; Neoplasm Proteins; Staurosporine; Survivin | 2007 |
Drug-induced Myc-mediated apoptosis of cancer cells is inhibited by stress protein Hsp70.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Camptothecin; Caspases; Cytochromes c; Enzyme Activation; Enzyme Inhibitors; Estrogens; Etoposide; Gene Expression Regulation, Neoplastic; HSP70 Heat-Shock Proteins; Humans; Lymphoma, Large B-Cell, Diffuse; Oncogene Proteins, Fusion; Proto-Oncogene Proteins c-myc; Translocation, Genetic; U937 Cells; Up-Regulation | 2007 |
Correlated three-dimensional light and electron microscopy reveals transformation of mitochondria during apoptosis.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cytochromes c; Etoposide; Fluorescent Dyes; HeLa Cells; Humans; Imaging, Three-Dimensional; Microscopy, Electron; Microscopy, Fluorescence; Mitochondria | 2007 |
Seleno-podophyllotoxin derivatives induce hepatoma SMMC-7721 cell apoptosis through Bax pathway.
Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Shape; Cytochromes c; Etoposide; Humans; Liver Neoplasms; Membrane Potentials; Mitochondria; Molecular Structure; Podophyllotoxin | 2008 |
The hierarchy of structural transitions induced in cytochrome c by anionic phospholipids determines its peroxidase activation and selective peroxidation during apoptosis in cells.
Topics: Animals; Apoptosis; Cardiolipins; Cytochromes c; Electron Spin Resonance Spectroscopy; Enzyme Activation; Etoposide; Fluorescence; Heme; Humans; Mice; Peroxidase; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphatidylserines; Phospholipids; Protein Structure, Tertiary; Tryptophan | 2007 |
Neuroprotective role of antidiabetic drug metformin against apoptotic cell death in primary cortical neurons.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cells, Cultured; Cerebral Cortex; Cyclosporine; Cytochromes c; Diabetic Neuropathies; Enzyme Inhibitors; Etoposide; Hypoglycemic Agents; Membrane Potential, Mitochondrial; Metformin; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar | 2008 |
Significance of mitochondrial calcium and nitric oxide for apoptosis of human breast cancer cells induced by tamoxifen and etoposide.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Calcium; Cell Line, Tumor; Cytochromes c; Dose-Response Relationship, Drug; Etoposide; Female; Humans; Membrane Potential, Mitochondrial; Mitochondria; Nitric Oxide; Tamoxifen; Time Factors; Tyrosine | 2008 |
DNA damage-inducing agents elicit gamma-secretase activation mediated by oxidative stress.
Topics: Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Apoptosis; Camptothecin; CHO Cells; Cricetinae; Cricetulus; Cytochromes c; DNA Damage; Enzyme Activation; Etoposide; Glutathione; Humans; Mice; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Oxidative Stress; Reactive Oxygen Species | 2008 |
Cathepsin D overexpressed by cancer cells can enhance apoptosis-dependent chemo-sensitivity independently of its catalytic activity.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Caspase 9; Catalysis; Cathepsin D; Cytochromes c; Cytosol; Drug Resistance, Neoplasm; Etoposide; Humans; Neoplasms; Pepstatins; Protease Inhibitors; Tumor Cells, Cultured | 2008 |
Caspase-mediated Bak activation and cytochrome c release during intrinsic apoptotic cell death in Jurkat cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptotic Protease-Activating Factor 1; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; bcl-X Protein; Caspases; Cell Membrane Permeability; Cytochromes c; DNA Damage; Drug Resistance, Neoplasm; Etoposide; Humans; Jurkat Cells; Mitochondrial Membranes; Protein Structure, Tertiary; X-Linked Inhibitor of Apoptosis Protein | 2008 |
Cleavage of Bid by executioner caspases mediates feed forward amplification of mitochondrial outer membrane permeabilization during genotoxic stress-induced apoptosis in Jurkat cells.
Topics: Antineoplastic Agents; Apoptosis; BH3 Interacting Domain Death Agonist Protein; Caspase 8; Caspases; Cell Separation; Cytochromes c; DNA Damage; Etoposide; Gene Expression Regulation; Humans; Jurkat Cells; Mitochondrial Membranes; Models, Biological; T-Lymphocytes | 2009 |
Changes of mitochondria and relocation of the apoptosis-inducing factor during apoptosis.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Inducing Factor; Cell Nucleus; Chromatin; Cytochromes c; Dactinomycin; DNA Fragmentation; Etoposide; Fluorescent Antibody Technique; HeLa Cells; HSP70 Heat-Shock Proteins; Humans; Microscopy, Confocal; Microscopy, Fluorescence; Mitochondria; Protein Transport; Time Factors | 2009 |
Targeting protein kinase C (PKC) and telomerase by phenethyl isothiocyanate (PEITC) sensitizes PC-3 cells towards chemotherapeutic drug-induced apoptosis.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biomarkers, Tumor; Caspases; Cell Line, Tumor; Cytochromes c; Down-Regulation; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Humans; Isothiocyanates; Male; Prostatic Neoplasms; Protein Kinase C; Telomerase | 2009 |
Activation of p73 and induction of Noxa by DNA damage requires NF-kappa B.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line; Cytochromes c; DNA Damage; DNA-Binding Proteins; Etoposide; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Humans; Metabolic Networks and Pathways; Mice; Nuclear Proteins; Promoter Regions, Genetic; Proto-Oncogene Proteins c-bcl-2; Transcription Factor RelA; Transcriptional Activation; Tumor Protein p73; Tumor Suppressor Proteins | 2009 |
Dynamic processes that reflect anti-apoptotic strategies set up by HspB1 (Hsp27).
Topics: Actins; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Caspase 3; Cytochalasin D; Cytochromes c; Enzyme Activation; Enzyme Inhibitors; Etoposide; fas Receptor; Fluorescent Antibody Technique; Heat-Shock Proteins; Heat-Shock Response; HeLa Cells; HSP27 Heat-Shock Proteins; Humans; Mitochondria; Molecular Chaperones; Nucleic Acid Synthesis Inhibitors; Phosphorylation; Signal Transduction; Staurosporine | 2010 |
Antagonism of cytotoxic chemotherapy in neuroblastoma cell lines by 13-cis-retinoic acid is mediated by the antiapoptotic Bcl-2 family proteins.
Topics: Alkylating Agents; Apoptosis; Biphenyl Compounds; Cell Line, Tumor; Cisplatin; Cytochromes c; Cytoprotection; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Isotretinoin; Melphalan; Membrane Potential, Mitochondrial; Mitochondria; Neuroblastoma; Nitrophenols; Piperazines; Protective Agents; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; Signal Transduction; Sulfonamides; Topoisomerase Inhibitors; Tumor Suppressor Protein p53 | 2010 |
Differential effects of Bcl-2 and caspases on mitochondrial permeabilization during endogenous or exogenous reactive oxygen species-induced cell death: a comparative study of H₂O₂, paraquat, t-BHP, etoposide and TNF-α-induced cell death.
Topics: Antioxidants; Apoptosis; Caspases; Cytochromes c; Etoposide; HeLa Cells; Humans; Hydrogen Peroxide; Membrane Potential, Mitochondrial; Mitochondria; Oxidants; Paraquat; Permeability; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; tert-Butylhydroperoxide; Tumor Necrosis Factor-alpha | 2012 |
zVAD-fmk upregulates caspase-9 cleavage and activity in etoposide-induced cell death of mouse embryonic fibroblasts.
Topics: Amino Acid Chloromethyl Ketones; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Caspase 3; Caspase 6; Caspase 9; Caspase Inhibitors; Cells, Cultured; Cytochromes c; Drug Synergism; Embryo, Mammalian; Enzyme Activation; Etoposide; Fibroblasts; Membrane Potential, Mitochondrial; Mice; Tumor Suppressor Protein p53; Up-Regulation | 2012 |
PKCδ promotes etoposide-induced cell death by phosphorylating Hsp27 in HeLa cells.
Topics: Apoptosis; Caspase 3; Cytochromes c; Etoposide; HeLa Cells; HSP27 Heat-Shock Proteins; Humans; Protein Kinase C-delta; Proteolysis; Recombinant Proteins; Serine | 2012 |
Pharmacological inhibition of GSK3 attenuates DNA damage-induced apoptosis via reduction of p53 mitochondrial translocation and Bax oligomerization in neuroblastoma SH-SY5Y cells.
Topics: Antibiotics, Antineoplastic; Apoptosis; bcl-2-Associated X Protein; bcl-Associated Death Protein; Camptothecin; Caspase 3; Cell Line, Tumor; Cytochromes c; DNA Damage; Doxorubicin; Etoposide; Gene Expression Regulation; Glycogen Synthase Kinase 3; Humans; Mitochondria; Neuroblastoma; Poly(ADP-ribose) Polymerases; Protein Multimerization; Protein Transport; Signal Transduction; Tumor Suppressor Protein p53 | 2013 |
Etoposide induces apoptosis via the mitochondrial- and caspase-dependent pathways and in non-cancer stem cells in Panc-1 pancreatic cancer cells.
Topics: Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Cell Line, Tumor; Cytochromes c; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Mitochondria; Neoplastic Stem Cells; Pancreatic Neoplasms; Signal Transduction | 2013 |
Caspase-cleaved arrestin-2 and BID cooperatively facilitate cytochrome C release and cell death.
Topics: Animals; Apoptosis; Arrestins; BH3 Interacting Domain Death Agonist Protein; Caspase 3; Caspases; Cell Line; Cytochromes c; Etoposide; Mice; Mitochondria; Protein Binding; Protein Isoforms; Recombinant Proteins; Tumor Necrosis Factor-alpha | 2014 |
Interaction of translationally controlled tumor protein with Apaf-1 is involved in the development of chemoresistance in HeLa cells.
Topics: Apoptosis; Apoptotic Protease-Activating Factor 1; Biomarkers, Tumor; Caspase 3; Caspase 9; Cell Death; Cytochromes c; DNA Fragmentation; Drug Resistance, Neoplasm; Epistasis, Genetic; ErbB Receptors; Etoposide; Gene Expression; HeLa Cells; Humans; Membrane Potential, Mitochondrial; Mitochondria; Phospholipase C gamma; Protein Binding; Protein Interaction Domains and Motifs; Topoisomerase II Inhibitors; Tumor Protein, Translationally-Controlled 1 | 2014 |
Chk1 activity is required for BAK multimerization in association with PUMA during mitochondrial apoptosis.
Topics: Apoptosis; Apoptosis Regulatory Proteins; bcl-2 Homologous Antagonist-Killer Protein; Caspases; Checkpoint Kinase 1; Cytochromes c; DNA Damage; Etoposide; HCT116 Cells; Humans; Mitochondria; Protein Kinases; Protein Multimerization; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Ultraviolet Rays | 2014 |
SPATA4 Counteracts Etoposide-Induced Apoptosis via Modulating Bcl-2 Family Proteins in HeLa Cells.
Topics: Apoptosis; Caspase 3; Caspase 9; Cytochromes c; Etoposide; HeLa Cells; Humans; Membrane Potential, Mitochondrial; Mitochondria; Proteins; Proto-Oncogene Proteins c-bcl-2; Topoisomerase II Inhibitors | 2015 |
Contrasting effects of glutamine deprivation on apoptosis induced by conventionally used anticancer drugs.
Topics: Antineoplastic Agents; Apoptosis; BH3 Interacting Domain Death Agonist Protein; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspase 8; Cell Line, Tumor; Cisplatin; Culture Media; Cytochromes c; Etoposide; Gene Expression Regulation, Neoplastic; Glutamine; Humans; Mitochondria; Neurons; Reactive Oxygen Species; Receptors, TNF-Related Apoptosis-Inducing Ligand; Signal Transduction; Tumor Suppressor Protein p53 | 2017 |
Induction of apoptotic DNA fragmentation mediated by mitochondrial pathway with caspase-3-dependent BID cleavage in human gastric cancer cells by a new nitroxyl spin-labeled derivative of podophyllotoxin.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Caspase 9; Cell Line, Tumor; Cytochromes c; DNA Fragmentation; Etoposide; Fluorouracil; Humans; Mitochondria; Podophyllotoxin; Spin Labels; Stomach Neoplasms | 2017 |
Resistance to apoptosis and autophagy leads to enhanced survival in Sertoli cells.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Autoimmune Diseases; Autophagy; Caspase 3; Cell Survival; Cisplatin; Cross-Sectional Studies; Cytochromes c; Disease Models, Animal; Etoposide; Fatty Alcohols; Gene Expression Regulation, Developmental; Humans; Infertility, Male; Male; Membrane Potential, Mitochondrial; Orchitis; Primary Cell Culture; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Sertoli Cells; Spermatogenesis; Staurosporine | 2017 |