etoposide has been researched along with cyclosporine in 188 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 50 (26.60) | 18.2507 |
| 2000's | 71 (37.77) | 29.6817 |
| 2010's | 62 (32.98) | 24.3611 |
| 2020's | 5 (2.66) | 2.80 |
| Authors | Studies |
|---|---|
| Aubé, J; Borchardt, RT; Gao, J; Murase, O; Schowen, RL | 1 |
| Belinsky, MG; Chen, ZS; Kruh, GD; Rea, PA; Zeng, H | 1 |
| Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA | 1 |
| Borchardt, RT; Horie, K; Tang, F | 2 |
| Belinsky, MG; Chen, ZS; Hopper-Borge, E; Kotova, E; Kruh, GD; Shchaveleva, I | 1 |
| Fischer, H; Huwyler, J; Poli, S; Schwab, D; Tabatabaei, A | 1 |
| Thakker, DR; Troutman, MD | 1 |
| Bacsó, Z; Cianfriglia, M; Fenyvesi, F; Goda, K; Kappelmayer, J; Lustyik, G; Nagy, H; Szabó, G; Szilasi, M | 1 |
| Chang, TK; Ensom, MH; Kiang, TK | 1 |
| Li, Y; Li, YH; Wang, YH; Yang, L; Yang, SL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Cai, W; Hao, Y; Hu, P; Ma, D; Pan, H; Xie, X; Yu, AD; Yu, J; Yuan, J; Zhang, L; Zhu, H | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L | 1 |
| Avdeef, A; Tam, KY | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, X; Lin, X; Skolnik, S; Wang, J | 1 |
| Arefolov, A; Clardy, J; Clarke, AS; Ishihara, K; Marks, KM; Park, ES; Pelish, HE; Ring, JE; Russo, K | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Alpeter, MD; Glisson, BS | 1 |
| Alder, KM; Brophy, NA; Fisher, GA; Gosland, MP; Halsey, J; Hardy, RI; Lum, BL; Sikic, BI; Yahanda, AM | 1 |
| Adler, KM; Brophy, NA; Ehsan, MN; Gosland, MP; Halsey, J; Jew, L; Kaubisch, S; Lum, BL; Sikic, BI; Yahanda, AM | 1 |
| Blume, KG; Chao, NJ; Kühl, JS; Sikic, BI | 2 |
| Cho, J; Slater, LM; Wetzel, M | 1 |
| Cho, J; Slater, LM; Sweet, P; Wetzel, M | 1 |
| Barnett, MJ; Dorovini-Zis, K; Frei-Lahr, DA; Gascoyne, RD; Graeb, DA; Herzig, GP; Klingemann, HG; Reece, DE; Shepherd, JD; Spinelli, JJ | 1 |
| Bender-Götze, C; Dopfer, R; Ebell, W; Ehninger, G; Friedrich, W; Gadner, H; Henze, G; Klingebiel, T; Peters, C; Riehm, H | 1 |
| Hussein, AM; Peters, WP; Stuart, A | 1 |
| Osann, K; Slater, L; Stupecky, M; Sweet, P; Wetzel, M | 1 |
| Boer, R; Ferry, DR; Gekeler, V; Ise, W; Kerr, DJ; Malkhandi, J | 1 |
| Adler, KM; Brophy, NA; Fisher, GA; Halsey, J; Lum, BL; Sikic, BI; Yahanda, AM | 1 |
| Reynolds, JT; Slater, LM; Stupecky, M; Sweet, P | 1 |
| Adler, KM; Brophy, NA; Fisher, GA; Halsey, J; Kaubisch, S; Lum, BL; Sikic, BI; Yahanda, AM | 1 |
| Ito, H; Kimura, Y; Nakamura, H; Nomura, N; Otaka, M; Sakai, N; Shirota, T; Suzuki, A; Toyama, K; Uchida, H | 1 |
| Amylon, MD; Chao, NJ; Long, GD; Nademanee, AP; Negrin, RS; O'Donnell, MR; Parker, PM; Smith, EP; Snyder, DS; Stein, AS | 1 |
| Bastie, JN; Baumelou, E; Casassus, P; Coloma, F; Delmas-Marsalet, B; Delmer, A; Faussat Suberville, AM; Leroux, G; Marie, JP; Rio, B | 1 |
| Gonzalez, FJ; Korzekwa, KR; Nemec, J; Relling, MV; Schuetz, EG; Schuetz, JD | 1 |
| Baur, R; Dartsch, PC; Höher, M; Hombach, V; Osterhues, H; Seitzer, U; Voisard, R | 1 |
| Cabanillas, F; Hagemeister, FB; McLaughlin, P; Moore, DF; Rodriguez, MA; Romaguera, J; Sarris, A; Swan, F; Yau, J; Younes, A | 1 |
| Burgio, DE; Gosland, MP; McNamara, PJ | 1 |
| Asaka, M; Hashino, S; Imamura, M; Kasai, M; Kobayashi, S; Noto, S; Sakurada, K; Tanaka, J | 1 |
| Bostrom, BC; Dehner, LP; Freyer, DR; Kennedy, R; Kohut, G | 1 |
| Ogretmen, B; Safa, AR | 1 |
| Burke, M; Crawford, DH; Hunt, BJ; Thomas, JA; Walker, H; Yacoub, M | 1 |
| Raez, LE; Saldana, M; Temple, JD | 1 |
| Adachi, I; Horikoshi, I; Kitazawa, H; Sato, H | 1 |
| Osann, K; Slater, LM; Stupecky, M; Sweet, P | 1 |
| Ford, PJ; Germann, UA; Harding, MW; Mason, VS; Shlyakhter, D | 1 |
| Baker, KS; DeLaat, CA; Filipovich, AH; Gross, TG; Harris, R; Loechelt, B; Shapiro, RS; Steinbuch, M | 1 |
| Bertola, A; Boiocchi, M; Corona, G; Sorio, R; Toffoli, G | 1 |
| Debatin, KM; Friesen, C; Fulda, S; Herr, I; Sieverts, H | 1 |
| Cho, J; Downey-Hurtado, N; Osann, K; Ramsinghani, N; Ross, HJ; Slater, LM; Williams, J; Wong, SF | 1 |
| Maia, RC; Noronha, H; Rumjanek, VM; Vasconcelos, FC | 1 |
| Borg, AG; Burgess, R; Fisher, A; Grey, M; Wood, P; Yin, JA | 1 |
| Carriço, MK; Coelho, AM; Klumb, CE; Maia, RC; Noronha, H; Ruimanek, VM; Vasconcelos, FC | 1 |
| Chan, HS; Doyle, J; Greenberg, ML; Karaskov, V; Koren, G; Malkin, D; Moncica, I; Theis, JG | 2 |
| Cowie, FJ; Pinkerton, CR; Pritchard-Jones, K; Renshaw, J | 1 |
| Kardos, G; van der Deure, J; von Blomberg-van der Flier, BM | 1 |
| Bisogno, G; Boddy, A; Cowie, F; Dick, G; Pinkerton, CR; Thomas, HD | 1 |
| Hibi, S; Imashuku, S; Kasubuchi, Y; Tsunamoto, K | 1 |
| Burgio, DE; Gosland, MP | 1 |
| Bogusławska-Jaworska, J; Gorczyńska, E; Słociak, M; Toporski, J | 1 |
| Bennett, JM; Lee, S; Paietta, E; Rowe, JM; Sikic, BI; Tallman, MS; Wiernik, PH | 1 |
| Berger, C; Braumann, D; de Witt, M; Erttmann, R; Fiedler, W; Grimm, J; Horstmann, M; Hossfeld, KD; Illiger, HJ; Kabisch, H; Kröger, N; Krüger, W; Kuse, R; Schönrock, P; Stockshläder, M; Weh, HJ; Zander, AR; Zeller, W | 1 |
| Abe, T; Arai, K; Arakawa, H; Asami, K; Hasegawa, D; Henter, JI; Hibi, S; Hisakawa, H; Ichimi, R; Igarashi, N; Imashuku, S; Iwai, A; Kataoka, S; Kato, M; Kawasaki, H; Kosaka, Y; Maeda, N; Maruhashi, K; Miyashita, H; Ohara, T; Sako, M; Sano, K; Sotomatsu, M; Tanizawa, A | 1 |
| Benoit, A; Bergametti, F; Luber, B; Prigent, S; Sarasin, A; Tiollais, P; Transy, C | 1 |
| Hasegawa, D; Hayakawa, A; Kosaka, Y; Nakamura, H; Sano, K | 1 |
| Ahmed, T; Baskind, P; Beer, M; Chiao, JW; Feldman, E; Goff, H; Seiter, K; Stein, M | 1 |
| Dong, H; Hirpara, JL; Kini, RM; Loh, KW; Pervaiz, S; Seyed, MA | 1 |
| Brown, BW; Fisher, GA; Kaubisch, S; Lum, BL; Sikic, BI | 1 |
| Benz, MS; Kramer, D; Murray, TG; Scott, IU; Toledano, S | 1 |
| Arceci, RJ; Brophy, N; Chang, M; Dahl, GV; Dunussi-Joannopoulos, K; Lacayo, NJ; Sikic, BI; Weinstein, HJ | 1 |
| Ammatuna, E; Barbera, V; Florena, AM; Franco, V; Gerlando, Q; Mariani, G | 1 |
| Brugarolas, A; Calvo, JP; Gonzalez Manzano, R; Jimenez, MM; Lopez-Picazo, JM; Ordoñez Tres, JM | 1 |
| Hashida, T; Hibi, S; Imashuku, S; Ishimoto, K; Itoh, E; Kawano, F; Tabata, Y; Tsunamoto, K | 1 |
| Carella, AM; Cavaliere, M; Corsetti, MT; De Stefano, F; Ferrara, R; Lambelet, P; Lerma, E; Loni, C; Pinotti, G; Romanelli, A; Tedeschi, L; Valbonesi, M; Verdiani, S; Vinci, M | 1 |
| Chow, W; Coluzzi, P; Doroshow, JH; Hamasaki, V; Leong, LA; Margolin, KA; Morgan, RJ; Raschko, JW; Shibata, SI; Somlo, G; Synold, TW; ter Veer, A; Tetef, ML; Yen, Y | 1 |
| Gastman, BR; Johnson, DE; Rabinowich, H; Wang, GQ; Watkins, SC; Wieckowski, E; Yin, XM | 1 |
| Kerokoski, P; Pirttilä, T; Salminen, A; Soininen, H; Suuronen, T | 1 |
| Hibi, S; Imashuku, S; Ishii, E; Kato, M; Kinugawa, N; Kuriyama, K; Sako, M; Teramura, T | 1 |
| Burnett, AK; Liu Yin, JA; Rees, JK; Wheatley, K | 1 |
| Emminger, W; Fritsch, G; Urbanek, R; Zlabinger, GJ | 1 |
| Harada, M; Mizoguchi, K; Moriwaki, A; Noguchi, T; Ogino, T; Okada, S; Tsuchiyama, J; Uno, M; Yoshino, T | 1 |
| Arai, K; Fukayama, M; Imashuku, S; Ito, E; Kitazawa, J; Yokoyama, M | 1 |
| Osann, KE; Slater, LM; Stupecky, M; Sweet, P | 1 |
| Emmenegger, U; Neftel, KA; Spaeth, PJ | 1 |
| Arcese, W; Cerretti, R; De Felice, L; Donato, V; Fenu, S; Guglielmi, C; Iori, A; Laurenti, L; Mengarelli, A; Micozzi, A; Romano, A; Torromeo, C | 1 |
| Baker, KS; Nagarajan, R; Neglia, J; Ramsay, N | 1 |
| Döhner, H; Gabler, A; Haas, R; Hartmann, F; Hensel, M; Ho, AD; Jung, W; Schlenk, RF; Trümper, L; Weber-Nordt, R | 1 |
| Becton, DL; Bomgaars, L; Chang, MN; Dahl, GV; Lacayo, NJ; Lauer, SJ; Lum, BL; Ravindranath, Y; Sikic, BI; Weinstein, H | 1 |
| Cavenagh, J; Chopra, R; Clark, FJ; Culligan, D; Davies, A; Fuller, S; Hunt, L; Hunter, A; Littlewood, T; Lush, R; Marks, DI; Marsh, J; Milligan, DW; Parker, A; Schey, S; Smith, GM; Towlson, K; Vandenberghe, E; Williams, CD; Yin, J | 1 |
| Davidson, A; Dick, G; Pinkerton, R; Pritchard-Jones, K | 1 |
| Kato, K; Kojima, S; Kudo, K; Matsuyama, T; Nakamoto, C; Nakamura, Y; Yoshimi, A | 1 |
| Araico, A; Cárcel-Trullols, J; Peris, JE; Saadeddin, A; Torres-Molina, F | 1 |
| Ejiri, M; Hara, S; Harima, A; Nakaseko, C; Nishimura, M; Saito, Y; Uehara, T; Yokota, A | 1 |
| Daenen, S; Ferrant, A; Huijgens, PC; Kramer, MH; Löwenberg, B; Schouten, HC; Sonneveld, P; Steijaert, MM; van den Berg, E; van der Holt, B; van Marwijk Kooy, R; Verdonck, LF; Verhoef, GE; Wijermans, PW | 1 |
| Kawa, K | 1 |
| Kaplan, SL | 1 |
| Miura, Y; Murata, Y; Tada, M; Takahara, K; Takahata, K; Utsumi, K | 1 |
| Anagnostopoulos, A; Anastasiou-Nana, MI; Dimopoulos, AM; Matsouka, C; Terrovitis, JV | 1 |
| Ariffin, H; Ariffin, WA; Chan, LL; Cheok, SA; Lin, HP; Lum, SH; Shekhar, K | 1 |
| Kang, JH; Lee, GK; Lee, JS; Park, HJ | 1 |
| De, S; Miller, DW; Robinson, DH | 1 |
| Maxwell, SA; Rivera, A | 1 |
| Filipovich, AH; Gadner, H; Henter, JI; Horne, A; Imashuku, S; Janka, G; Ladisch, S; Locatelli, F; Maarten Egeler, R; Montgomery, SM; Webb, D; Winiarski, J | 1 |
| Bernstein, M; Blaney, S; Chen, Z; Fisher, PG; Freeman, C; Friedman, H; Greenberg, ML; Hershon, L; Korones, DN; Kretschmar, C; Zhou, T | 1 |
| Bader, P; Boppana, S; Dormann, S; Fisch, P; Goebel, H; Jung, A; Kontny, U; Niemeyer, C; Peters, A; Strahm, B; Werner, M | 1 |
| Apostolidis, I; Arvanitopoulou, E; Asprogeraka, T; Bakiri, M; Giannakoulas, N; Kotsianidis, I; Marinakis, T; Matsouka, P; Pagoni, M; Papaioannou, M; Skandali, A; Spanoudakis, E; Tsatalas, K; Viniou, N; Yataganas, X; Zikos, P | 1 |
| Inoue, M; Kawa, K; Sakata, A; Takeshita, Y | 1 |
| Farber, JL; Karpinich, NO; Russo, MA; Schneider, T; Tafani, M | 1 |
| Bellyei, S; Bognar, Z; Boronkai, A; Gallyas, F; Gasz, B; Hocsak, E; Minik, O; Sumegi, B; Szigeti, A; Varbiro, G | 1 |
| Assanasen, T; Intragumtornchai, T; Nakorn, TN; Rojnuckarin, P; Wannakrairot, P | 1 |
| Chiba, S; Izutsu, K; Kako, S; Kanda, Y; Kurokawa, M; Motokura, T; Oshima, K; Sato, H | 1 |
| Fernández-Pérez, ER; Jama, AA | 1 |
| Akimoto, M; Arima, N; Hamada, H; Horai, S; Kawada, H; Matsushita, K; Ozaki, A; Tanaka, Y; Tei, C; Uozumi, K | 1 |
| Almeida, A; Attia, S; Delgado-Esteban, M; Detaille, D; El-Mir, MY; Fontaine, E; Guigas, B; Leverve, X; R-Villanueva, G | 1 |
| Abdelhaleem, M; Benseler, S; Gupta, AA; Tyrrell, P; Valani, R; Weitzman, S | 1 |
| Ishida, Y; Ishii, E; Kudo, K; Morimoto, A; Ohga, S; Suzuki, N | 1 |
| Cervinka, M; Rudolf, E; Rudolf, K | 1 |
| Chan, HS; Dimaras, H; Gallie, BL; Halliday, W; Héon, E; Khetan, V | 1 |
| Chang, SE; Choi, JH; Kim, CH; Lee, DW; Lee, MW; Lee, WJ; Moon, KC; Won, CH | 1 |
| Grigg, AP; Hoyt, R; Ritchie, DS; Szer, J; Wirth, A | 1 |
| Escoto, H; Kalpatthi, R; Ringewald, J | 1 |
| Dzieciatkowski, T; Jedrzejczak, WW; Luczak, M; Przybylski, M; Zduńczyk, D | 1 |
| Fiedler, W; Habermann, RC; Janka-Schaub, GE; Kluge, S; Wolschke, Ch | 1 |
| Aziz, HA; Aziz-Sultan, MA; Boutrid, H; Fernandes, CE; Houston, SK; Markoe, AM; Moftakhar, R; Murray, TG; Piña, Y; Reichbach, J; Schefler, AC; Wolfe, SQ | 1 |
| Imashuku, S | 1 |
| Ozdemirli, M; Sathiyamoorthy, S; Shad, A | 1 |
| Babyn, P; Chan, HS; Dimaras, H; Doyle, J; Gallie, BL; Halliday, W; Héon, E; Paton, KE; Strahlendorf, C | 1 |
| Currimbhoy, Z; Desai, M; Joshi, R; Phatarpekar, A | 1 |
| Aricò, M; Berglöf, E; Beutel, K; Henter, JI; Horne, A; Janka, G; Lehmberg, K; Onelöv, E; Sieni, E; Silfverberg, T; Trottestam, H | 1 |
| Fujita-Hamabe, W; Kishioka, S; Kobori, T; Nakamoto, K; Nawa, A; Nishida, M; Tokuyama, S | 1 |
| Donthireddy, V; Munoz, J; Shareef, N | 1 |
| Bayrakci, B; Carcillo, JA; Citak, A; Demirkol, D; Dursun, O; Erkek, N; Gedik, H; Karabocuoglu, M; Karapinar, B; Kendirli, T; Kesici, S; Koroglu, TF; Yildizdas, D | 1 |
| Jovanovic, A; Kosutic, J; Kuzmanovic, M; Pasic, S; Prijic, S | 1 |
| Arai, A; Fujiwara, S; Imadome, K; Kurata, M; Miura, O; Murakami, N; Nogami, A | 1 |
| Higa, B; Velankar, M | 1 |
| Rajagopala, S; Singh, N | 1 |
| Chen, TL; Estey, EH; Gardner, KM; Markle, LJ; Othus, M; Walter, RB | 1 |
| Goda, F; Otaka, Y; Sakurai, Y; Sato, M; Soma, H; Watanabe, T | 1 |
| Imashuku, S; Kubo, K; Kudo, N; Yachie, A | 1 |
| Komagata, Y | 1 |
| Mayson, E; Saverimuttu, J; Warburton, P | 1 |
| Asano, T; Ishii, E; Kanegane, H; Kogawa, K; Kudo, K; Morimoto, A; Oda, M; Ohga, S; Ohta, S; Sato, H; Wakiguchi, H | 1 |
| Imamura, Y | 1 |
| Ashok, I; Gowrishankar, K; Manwani, N; Rajajee, S; Rajkumar, J; Subbiah, E | 1 |
| Alessio, M; Anton, J; Avcin, T; Bovis, F; Chasnyk, V; Cron, RQ; Davì, S; Demirkaya, E; Espada, G; Fischbach, M; Frosch, M; Gao, YJ; Grom, A; Horne, A; Huasong, Z; Huber, A; Insalaco, A; Jelusic, M; Kasapcopur, O; Khubchandani, R; Kitoh, T; Lehmberg, K; Li, C; Maritsi, D; Martini, A; Merino, R; Miettunen, P; Minoia, F; Ozen, S; Pal, P; Ravelli, A; Ruperto, N; Russo, R; Sanner, H; Sawhney, S; Shakoory, B; Shenoi, S; Uziel, Y; Weitzman, S; Wouters, C | 1 |
| Thia, K; Trapani, JA; Voskoboinik, I | 1 |
| Shoenfeld, Y; Soriano, A | 1 |
| Dehoedt, C; Jin, F; Li, F; Li, P; Rao, J; Wang, M; Yang, G; Yang, Y; Zhang, R; Zhou, Y | 1 |
| Dadashzadeh, S; Khezrian, M; Lavasani, H; Rouini, M; Sheikholeslami, B | 1 |
| Eberle, C; Guttek, K; Hartig, R; Heiserich, L; Hiemann, R; Lorenz, S; Peters, V; Reddig, A; Reinhold, D; Roggenbuck, D; Sack, U; Schierack, P | 1 |
| Balcı, YI; Greenwood, T; Kenar, F; Koçyiğit, A; Özgürler Akpınar, F; Polat, A; Tesi, B; Yalçın, N | 1 |
| Andrzej, S; Kamila, ŻW; Patrycja, MG; Teresa, R | 1 |
| Beffermann C, N; Ocqueteau T, M; Pilcante S, J; Sarmiento M, M | 1 |
| La Rosée, P | 1 |
| Chen, CC; Teng, CL; Yeh, SP | 1 |
| Rosen, D; Sinno, MG; Wittler, R | 1 |
| Cheng, FW; Lin, A; Ma, TP; Ng, PC | 1 |
| Halliday, M; Ross, J; Southgate, WM | 1 |
| Hasegawa, D; Imadome, KI; Ishida, T; Kosaka, Y; Maruyama, A; Nagase, H; Takeda, H; Tanaka, T; Uetani, Y; Yamaguchi, H; Yokoi, T | 1 |
| Abe, Y; Ikeda, M; Ishida, T; Miyazaki, K; Oba, R; Shingaki, S; Suzuki, K; Takei, T; Tsukada, N; Yoshiki, Y | 1 |
| Báez, M; Borjas-Aguilar, KL; García-Pavón, S; Murata, C; Yamazaki-Nakashimada, MA | 1 |
| Aricó, M; Astigarraga, I; Bergsten, E; Egeler, RM; Filipovich, AH; Henter, JI; Horne, A; Ishii, E; Janka, G; Ladisch, S; Lehmberg, K; McClain, KL; Minkov, M; Montgomery, S; Nanduri, V; Rosso, D | 1 |
| Almuwaqqat, Z; Bashtawi, Y; Roberts, JW | 1 |
| Carlsen, KL; Gé, LG; Nielsen, CU; Nielsen, S; Pedersen, MDL; Westerhoff, AM | 1 |
| Cardarelli, L; Chiaretti, S; Diverio, D; Foà, R; Giona, F; Mancini, F; Miano, M; Moleti, ML; Nanni, M; Palumbo, G; Peragine, N; Santopietro, M; Testi, AM; Zhang, K | 1 |
| Cosgrove, C; Dhariwal, A; Ellis, L; Jawad, S; Reyal, Y | 1 |
| Li, Z; Liu, W; Ma, H; Qin, M; Wang, T; Wei, A; Yang, Y; Zhang, L; Zhang, R; Zhao, X | 1 |
| Maeda, S; Naniwa, T; Ohmura, SI; Tamechika, S; Uehara, K; Yamabe, T | 1 |
| Kanegane, H; Kong, P; Tang, X; Yan, X; Yang, X; Yao, H; Zhang, X; Zhang, Z; Zhao, Q; Zhao, X | 1 |
| Hiraoka, E; Iwanami, K; Matsuo, Y; Oda, R | 1 |
17 review(s) available for etoposide and cyclosporine
| Article | Year |
|---|---|
UDP-glucuronosyltransferases and clinical drug-drug interactions.
Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic | 2005 |
Membrane transporters in drug development.
Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs | 2010 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Clinical reversal of multidrug resistance.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Clinical Trials as Topic; Cyclosporine; Drug Resistance, Multiple; Etoposide; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Neoplasms; Paclitaxel; Pharmaceutical Preparations; Verapamil | 1994 |
Clinical trials of modulation of multidrug resistance. Pharmacokinetic and pharmacodynamic considerations.
Topics: Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Clinical Trials as Topic; Cyclosporine; Drug Resistance; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Membrane Glycoproteins; Neoplasm Proteins; Neoplasms | 1993 |
Juvenile xanthogranuloma: forms of systemic disease and their clinical implications.
Topics: Anti-Inflammatory Agents; Brain Diseases; Child; Child, Preschool; Cyclosporine; Etoposide; Humans; Immunosuppressive Agents; Infant; Infant, Newborn; Liver Diseases; Lung Diseases; Male; Prednisone; Remission, Spontaneous; Skin; Splenic Diseases; Survival Rate; Treatment Outcome; Vinblastine; Xanthogranuloma, Juvenile | 1996 |
[Familial hemophagocytic lymphohistiocytosis].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclosporine; Dexamethasone; Drug Administration Schedule; Etoposide; Genes, Recessive; Histiocytosis, Non-Langerhans-Cell; Humans; Methotrexate | 1998 |
Outcome of clonal hemophagocytic lymphohistiocytosis: analysis of 32 cases.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aneuploidy; Bone Marrow Transplantation; Child; Child, Preschool; Clone Cells; Combined Modality Therapy; Cyclosporine; Drug Therapy, Combination; Epstein-Barr Virus Infections; Etoposide; Female; Gene Rearrangement, T-Lymphocyte; Herpesvirus 4, Human; Histiocytosis, Non-Langerhans-Cell; Humans; Infant; Japan; Male; Prednisolone; Prognosis; Treatment Outcome | 2000 |
Successful treatment of refractory Langerhans cell histiocytosis with unrelated cord blood transplantation.
Topics: Bone Marrow; Cladribine; Combined Modality Therapy; Cyclosporine; Cytarabine; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Fetal Blood; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Histiocytosis, Langerhans-Cell; Humans; Infant, Newborn; Mercaptopurine; Methotrexate; Methylprednisolone; Prednisone; Remission Induction; Transplantation, Homologous; Vinblastine | 2001 |
[Diagnosis and treatment of hemophagocytic syndrome].
Topics: Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Cyclosporine; Cytokines; Dexamethasone; Drug Therapy, Combination; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Lymphohistiocytosis, Hemophagocytic; Macrophages; Plasma Exchange; Severity of Illness Index; T-Lymphocytes | 2005 |
Diagnosing and treating hemophagocytic lymphohistiocytosis in the tropics: systematic review from the Indian subcontinent.
Topics: Cyclosporine; Etoposide; Humans; Immunoglobulins, Intravenous; Immunosuppressive Agents; India; Infections; Lymphohistiocytosis, Hemophagocytic; Steroids; Tropical Climate | 2012 |
[Serious organ damage and intractable clinical conditions in rheumatic and connective tissue disease--progress in pathophysiology and treatment. Topics: II. Clinical conditions special attention needed to be paid to; 4. Macrophage activating syndrome and
Topics: Antirheumatic Agents; Connective Tissue Diseases; Cyclosporine; Dexamethasone; Drug Therapy, Combination; Etoposide; gamma-Globins; Humans; Immunosuppressive Agents; Lymphohistiocytosis, Hemophagocytic; Macrophage Activation Syndrome; Methotrexate; Methylprednisolone; Pulse Therapy, Drug | 2013 |
[Hemophagocytic lymphohistiocytosis].
Topics: Antibodies, Monoclonal, Murine-Derived; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cord Blood Stem Cell Transplantation; Cyclophosphamide; Cyclosporine; Disease Progression; Doxorubicin; Drug Therapy, Combination; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Lymphohistiocytosis, Hemophagocytic; Methotrexate; Multiple Organ Failure; Prednisolone; Prednisone; Rituximab; Severity of Illness Index; Transplantation Conditioning; Vidarabine; Vincristine | 2014 |
[Acquired hemophagocytic syndrome treated with HLH 94-04 chemotherapy protocol: Report of four cases].
Topics: Adult; Cyclosporine; Dexamethasone; Drug Therapy, Combination; Early Diagnosis; Etoposide; Female; Ferritins; Humans; Immunosuppressive Agents; Lymphohistiocytosis, Hemophagocytic; Male; Methotrexate; Young Adult | 2015 |
Relapsed and refractory subcutaneous panniculitis-like T-cell lymphoma with excellent response to cyclosporine: a case report and literature review.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclosporine; Cytarabine; Deoxycytidine; Dexamethasone; Drug Resistance, Neoplasm; Etoposide; Gemcitabine; Humans; Immunosuppressive Agents; Lymphoma, T-Cell, Cutaneous; Male; Methylprednisolone; Multimodal Imaging; Panniculitis; Positron-Emission Tomography; Recurrence; Remission Induction; Salvage Therapy; Skin Neoplasms; Subcutaneous Fat; Tomography, X-Ray Computed | 2016 |
Clinically Mild Encephalitis/Encephalopathy With a Reversible Splenial Lesion Accompanied by Epstein-Barr Virus Hemophagocytic Lymphohistiocytosis: A Case Report and Review of the Literature.
Topics: Bone Marrow; Corpus Callosum; Cyclosporine; Delirium; Dexamethasone; Diffusion Magnetic Resonance Imaging; Drug Therapy, Combination; Encephalitis; Epstein-Barr Virus Infections; Etoposide; Humans; Hyponatremia; Lymphohistiocytosis, Hemophagocytic; Methylprednisolone; Neuroimaging; Prognosis; Pulse Therapy, Drug | 2017 |
Kawasaki Disease Complicated With Macrophage Activation Syndrome: A Systematic Review.
Topics: Adolescent; Adrenal Cortex Hormones; Antibodies, Monoclonal; Aspartate Aminotransferases; Child; Child, Preschool; Coronary Vessel Anomalies; Cyclosporine; Etoposide; Female; Fever; Humans; Infant; Macrophage Activation Syndrome; Male; Mucocutaneous Lymph Node Syndrome; Tumor Necrosis Factor-alpha | 2017 |
23 trial(s) available for etoposide and cyclosporine
| Article | Year |
|---|---|
Phase I trial of etoposide with cyclosporine as a modulator of multidrug resistance.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclosporine; Drug Resistance; Etoposide; Female; Gene Expression; Humans; Male; Middle Aged; Neoplasms | 1992 |
Alteration of etoposide pharmacokinetics and pharmacodynamics by cyclosporine in a phase I trial to modulate multidrug resistance.
Topics: Adult; Aged; Cyclosporine; Drug Interactions; Drug Resistance; Etoposide; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasms | 1992 |
Allogeneic bone marrow transplantation for childhood acute lymphoblastic leukemia in second remission after intensive primary and relapse therapy according to the BFM- and CoALL-protocols: results of the German Cooperative Study.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Child; Child, Preschool; Cyclophosphamide; Cyclosporine; Daunorubicin; Etoposide; Follow-Up Studies; Graft vs Host Disease; Humans; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Recurrence; Time Factors; Transplantation, Homologous; Vincristine; Whole-Body Irradiation | 1991 |
Clinical reversal of multidrug resistance.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Clinical Trials as Topic; Cyclosporine; Drug Resistance, Multiple; Etoposide; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Neoplasms; Paclitaxel; Pharmaceutical Preparations; Verapamil | 1994 |
Fractionated total-body irradiation and high-dose etoposide as a preparatory regimen for bone marrow transplantation for 94 patients with chronic myelogenous leukemia in chronic phase.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Cause of Death; Child; Chromosome Aberrations; Chromosome Disorders; Cyclosporine; Cytogenetics; Drug Therapy, Combination; Etoposide; Female; Graft vs Host Disease; Humans; Immunosuppression Therapy; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Methotrexate; Methylprednisolone; Middle Aged; Recurrence; Survival Rate; Whole-Body Irradiation | 1994 |
Cyclosporin A as a modifier agent in the salvage treatment of acute leukemia (AL).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Cyclosporine; Etoposide; Female; Humans; Leukemia; Male; Membrane Glycoproteins; Middle Aged; Mitoxantrone | 1993 |
Cyclosporin plus doxorubicin, vincristine and etoposide in the treatment of refractory non-Hodgkin's lymphoma: a phase II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclosporine; Doxorubicin; Etoposide; Female; Humans; Lymphoma, Non-Hodgkin; Male; Middle Aged; Vincristine | 1995 |
Phase I/II trial of low dose cyclosporin A with EP for advanced non-small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cyclosporine; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Survival Rate | 1997 |
Increased systemic toxicity of sarcoma chemotherapy due to combination with the P-glycoprotein inhibitor cyclosporin.
Topics: Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Child; Cyclophosphamide; Cyclosporine; Dactinomycin; Drug Interactions; Etoposide; Fever; Humans; Ifosfamide; Immunosuppressive Agents; Neutropenia; Patient Admission; Retrospective Studies; Sarcoma; Sepsis; Soft Tissue Neoplasms; Vincristine | 1998 |
High-dose cyclosporin with etoposide--toxicity and pharmacokinetic interaction in children with solid tumours.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclosporine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Etoposide; Female; Humans; Male; Neoplasms | 1998 |
High dose chemotherapy with busulfan, cyclophosphamide, and etoposide as conditioning regimen for allogeneic bone marrow transplantation for patients with acute myeloid leukemia in first complete remission.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cyclophosphamide; Cyclosporine; Disease-Free Survival; Etoposide; Female; Graft vs Host Disease; Humans; Immunosuppressive Agents; Leukemia, Myeloid; Male; Methotrexate; Methylprednisolone; Middle Aged; Remission Induction; Time Factors; Transplantation, Homologous | 1997 |
Effect of high-dose cyclosporine on etoposide pharmacodynamics in a trial to reverse P-glycoprotein (MDR1 gene) mediated drug resistance.
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Area Under Curve; Bone Marrow Diseases; Chromatography, High Pressure Liquid; Cyclosporine; Drug Resistance, Neoplasm; Erythroid Precursor Cells; Etoposide; Female; Genes, MDR; Humans; Immunosuppressive Agents; Infusions, Intravenous; Leukocyte Count; Leukopenia; Male; Middle Aged | 2000 |
Mitoxantrone, etoposide, and cyclosporine therapy in pediatric patients with recurrent or refractory acute myeloid leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclosporine; Drug Resistance, Multiple; Etoposide; Female; Flow Cytometry; Genes, MDR; Humans; Immunosuppressive Agents; Infant; Infant, Newborn; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Recurrence; Reverse Transcriptase Polymerase Chain Reaction; Treatment Outcome | 2000 |
Autografting followed by nonmyeloablative immunosuppressive chemotherapy and allogeneic peripheral-blood hematopoietic stem-cell transplantation as treatment of resistant Hodgkin's disease and non-Hodgkin's lymphoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cyclophosphamide; Cyclosporine; Cytarabine; Etoposide; Female; Graft vs Tumor Effect; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Hodgkin Disease; Humans; Immunosuppressive Agents; Lymphoma, Non-Hodgkin; Male; Melphalan; Methotrexate; Middle Aged; Pilot Projects; Risk Factors; Survival Rate; Transplantation Chimera; Vidarabine | 2000 |
A phase I study of carboplatin and etoposide administered in conjunction with dipyridamole, prochlorperazine and cyclosporine A.
Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cyclosporine; Dipyridamole; Etoposide; Female; Humans; Immunosuppressive Agents; Male; Middle Aged; Neoplasms; Prochlorperazine; Treatment Outcome; Vasodilator Agents | 2000 |
Comparison of 'sequential' versus 'standard' chemotherapy as re-induction treatment, with or without cyclosporine, in refractory/relapsed acute myeloid leukaemia (AML): results of the UK Medical Research Council AML-R trial.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclosporine; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Administration Schedule; Etoposide; Female; Humans; Immunosuppressive Agents; Leukemia, Myeloid; Male; Middle Aged; Remission Induction | 2001 |
Less intense conditioning with fludarabine, cyclophosphamide, idarubicin and etoposide (FCIE) followed by allogeneic unselected peripheral blood stem cell transplantation in elderly patients with leukemia.
Topics: Adult; Aged; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Cyclosporine; Etoposide; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Immunosuppressive Agents; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Chronic-Phase; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Pilot Projects; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Survival Rate; Transplantation Conditioning; Transplantation, Homologous; Vidarabine | 2002 |
Pharmacokinetic interactions of cyclosporine with etoposide and mitoxantrone in children with acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Child; Child, Preschool; Chromatography, High Pressure Liquid; Cyclosporine; Drug Interactions; Drug Resistance, Multiple; Etoposide; Female; Humans; Infant; Leukemia, Myeloid; Male; Metabolic Clearance Rate; Mitoxantrone | 2002 |
Addition of cyclosporin A to the combination of mitoxantrone and etoposide to overcome resistance to chemotherapy in refractory or relapsing acute myeloid leukaemia: a randomised phase II trial from HOVON, the Dutch-Belgian Haemato-Oncology Working Group
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclosporine; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Prognosis; Recurrence; Regression Analysis; Survival Analysis; Treatment Outcome | 2004 |
Etoposide, vincristine, and cyclosporin A with standard-dose radiation therapy in newly diagnosed diffuse intrinsic brainstem gliomas: a pediatric oncology group phase I study.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Stem Neoplasms; Child; Child, Preschool; Combined Modality Therapy; Cyclosporine; Disease Progression; Dose Fractionation, Radiation; Etoposide; Glioma; Humans; Radiotherapy Dosage; Vincristine | 2005 |
Addition of cyclosporin-A to chemotherapy in secondary (post-MDS) AML in the elderly. A multicenter randomized trial of the Leukemia Working Group of the Hellenic Society of Hematology.
Topics: Acute Disease; Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclosporine; Cytarabine; Data Interpretation, Statistical; Disease-Free Survival; Etoposide; Female; Follow-Up Studies; Greece; Humans; Idarubicin; Infusions, Intravenous; Leukemia, Myeloid; Male; Middle Aged; Neoplasms, Second Primary; Remission Induction; Societies, Medical; Survival Analysis; Treatment Outcome | 2006 |
Cyclosporine modulation of multidrug resistance in combination with pravastatin, mitoxantrone and etoposide for adult patients with relapsed/refractory acute myeloid leukemia: a phase 1/2 study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclosporine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Pravastatin; Treatment Outcome | 2013 |
Prognostic factors of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in children: report of the Japan Histiocytosis Study Group.
Topics: Adrenal Cortex Hormones; Age of Onset; Antineoplastic Agents, Phytogenic; Asian People; Bilirubin; Child; Child, Preschool; Cyclosporine; Data Collection; Disease-Free Survival; Epstein-Barr Virus Infections; Etoposide; Herpesvirus 4, Human; Humans; Hyperbilirubinemia; Immunosuppressive Agents; Infant; Japan; Lymphohistiocytosis, Hemophagocytic; Remission Induction; Retrospective Studies; Survival Rate | 2014 |
149 other study(ies) available for etoposide and cyclosporine
| Article | Year |
|---|---|
A functional assay for quantitation of the apparent affinities of ligands of P-glycoprotein in Caco-2 cells.
Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Biological Transport, Active; Caco-2 Cells; Drug Interactions; Humans; Ligands; Models, Theoretical; Paclitaxel; Tritium | 2001 |
Transport of methotrexate (MTX) and folates by multidrug resistance protein (MRP) 3 and MRP1: effect of polyglutamylation on MTX transport.
Topics: 3T3 Cells; Animals; ATP-Binding Cassette Transporters; Biological Transport; Drug Resistance, Multiple; Folic Acid; Humans; Leucovorin; Methotrexate; Mice; Multidrug Resistance-Associated Proteins; Osmolar Concentration; Polyglutamic Acid; Tritium | 2001 |
Rational use of in vitro P-glycoprotein assays in drug discovery.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera | 2001 |
Are MDCK cells transfected with the human MDR1 gene a good model of the human intestinal mucosa?
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Cell Line; Digoxin; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Genes, MDR; Humans; Intestinal Mucosa; Transfection | 2002 |
Are MDCK cells transfected with the human MRP2 gene a good model of the human intestinal mucosa?
Topics: Animals; Caco-2 Cells; Cell Line; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Intestinal Mucosa; Mitochondrial Proteins; Multidrug Resistance-Associated Protein 2; Ribosomal Proteins; Saccharomyces cerevisiae Proteins; Transfection; Vinblastine | 2002 |
Characterization of the transport properties of human multidrug resistance protein 7 (MRP7, ABCC10).
Topics: Biological Transport; Cells, Cultured; Cyclosporine; Estradiol; Glycocholic Acid; Humans; Kinetics; Leukotriene Antagonists; Leukotriene C4; Multidrug Resistance-Associated Proteins; Osmotic Pressure; Propionates; Quinolines; Recombinant Proteins; Transfection | 2003 |
Comparison of in vitro P-glycoprotein screening assays: recommendations for their use in drug discovery.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cells, Cultured; Drug Evaluation, Preclinical; Fluoresceins; Fluorescent Dyes; Humans; Indicators and Reagents; Mice; Models, Molecular; Rhodamines; Species Specificity; Swine | 2003 |
Novel experimental parameters to quantify the modulation of absorptive and secretory transport of compounds by P-glycoprotein in cell culture models of intestinal epithelium.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blotting, Western; Cells, Cultured; Diffusion; Humans; Intestinal Absorption; Intestinal Mucosa; Models, Biological; Permeability; Pharmaceutical Preparations; Pharmacokinetics | 2003 |
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies.
Topics: Adenosine Triphosphatases; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Calcium Channel Blockers; Cyclosporine; Detergents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Humans; Ivermectin; Mice; NIH 3T3 Cells; Substrate Specificity | 2004 |
Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism.
Topics: Computational Biology; Cyclohexanols; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Molecular Structure; Principal Component Analysis; Pyrrolizidine Alkaloids; Quantitative Structure-Activity Relationship; Reproducibility of Results; Substrate Specificity; Venlafaxine Hydrochloride | 2005 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Small molecule regulators of autophagy identified by an image-based high-throughput screen.
Topics: Autophagy; Calcium Channel Blockers; Cell Line, Tumor; Drug Evaluation, Preclinical; Fluspirilene; Glioblastoma; Green Fluorescent Proteins; Humans; Intracellular Membranes; Loperamide; Microtubule-Associated Proteins; Mycotoxins; Peptides; Phagosomes; Phosphatidylinositol Phosphates; Pimozide; Protein Kinases; Recombinant Fusion Proteins; Sirolimus; Small Molecule Libraries; TOR Serine-Threonine Kinases; Trifluoperazine; Zinc Fingers | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity | 2011 |
The selectivity of austocystin D arises from cell-line-specific drug activation by cytochrome P450 enzymes.
Topics: Aflatoxin B1; Aflatoxins; Antineoplastic Agents; Aspergillus; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Cytochrome P-450 Enzyme System; DNA Damage; Drug Resistance, Multiple; Drug Screening Assays, Antitumor; Humans; Molecular Structure | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Multidrug resistance in a small cell lung cancer line: rapid selection with etoposide and differential chemosensitization with cyclosporin A.
Topics: Alkalies; Biological Transport; Carcinoma, Small Cell; Cell Division; Cell Nucleus; Cyclosporine; DNA Topoisomerases, Type II; Drug Resistance; Etoposide; Lung Neoplasms; Organelles; Phenotype; Ribonucleases; Tumor Cells, Cultured | 1992 |
Use of etoposide in combination with cyclosporine for purging multidrug resistant leukemic cells from bone marrow in a mouse model.
Topics: Animals; Bone Marrow Purging; Bone Marrow Transplantation; Cyclosporine; Drug Evaluation, Preclinical; Drug Resistance; Etoposide; Leukemia P388; Mice; Tumor Stem Cell Assay | 1992 |
Cyclosporin A potentiation of VP-16: production of long-term survival in murine acute lymphatic leukemia.
Topics: Animals; Cyclosporine; Drug Synergism; Etoposide; Female; Leukemia L1210; Leukemia P388; Mice; Mice, Inbred Strains; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Survival Rate; Time Factors | 1992 |
Use of etoposide in combination with cyclosporin for purging multidrug-resistant leukemic cells from bone marrow in a mouse model.
Topics: Animals; Bone Marrow; Bone Marrow Purging; Cyclosporine; Disease Models, Animal; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Etoposide; Leukemia, Experimental; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Tumor Cells, Cultured | 1992 |
Development of cyclosporin A mediated immunity in L1210 leukaemia.
Topics: Animals; Cyclosporine; Drug Synergism; Etoposide; Immunity; Immunization, Passive; Leukemia L1210; Mice; Spleen; Survival Analysis | 1991 |
Neurologic complications in allogeneic bone marrow transplant patients receiving cyclosporin.
Topics: Adolescent; Adult; Anemia, Hemolytic; Bone Marrow Transplantation; Child; Cyclosporine; Etoposide; Female; Humans; Hypertension; Male; Middle Aged; Nervous System Diseases; Occipital Lobe; Seizures; Syndrome; Tomography, X-Ray Computed; Transplantation, Homologous; Vision Disorders | 1991 |
Protection against chemotherapy-induced alopecia by cyclosporin A in the newborn rat animal model.
Topics: Administration, Cutaneous; Alopecia; Animals; Animals, Newborn; Antineoplastic Agents; Cyclophosphamide; Cyclosporine; Cytarabine; Disease Models, Animal; Etoposide; Injections, Intraperitoneal; Rats; Rats, Sprague-Dawley | 1995 |
Comparison of cyclosporin A, verapamil, PSC-833 and cremophor EL as enhancing agents of VP-16 in murine lymphoid leukemias.
Topics: Animals; Cell Survival; Cyclosporine; Cyclosporins; Drug Synergism; Etoposide; Glycerol; Leukemia L1210; Leukemia P388; Mice; Survival Analysis; Tumor Cells, Cultured; Verapamil | 1995 |
Dexniguldipine-HCl is a potent allosteric inhibitor of [3H]vinblastine binding to P-glycoprotein of CCRF ADR 5000 cells.
Topics: Allosteric Regulation; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Calcium Channel Blockers; Cell Division; Cyclosporine; Dihydropyridines; Doxorubicin; Drug Resistance, Multiple; Etoposide; Humans; Kinetics; Mathematics; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tritium; Tumor Cells, Cultured; Vinblastine; Vincristine | 1994 |
Cyclosporin A/VP-16 produced immunity to L1210 leukemia: the participation of cytotoxic CD8 T-lymphocytes.
Topics: Animals; CD8-Positive T-Lymphocytes; Cyclosporine; Cytotoxicity, Immunologic; Etoposide; Immunity, Cellular; Immunization, Passive; Leukemia L1210; Lymphocyte Depletion; Mice; Spleen; T-Lymphocytes, Cytotoxic | 1995 |
Successful bone marrow transplant for a patient with T-lymphoblastic lymphoma in second remission preconditioned by total-body irradiation plus melphalan and etoposide.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cyclosporine; Etoposide; Graft vs Host Disease; Humans; Male; Melphalan; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Whole-Body Irradiation | 1994 |
O-demethylation of epipodophyllotoxins is catalyzed by human cytochrome P450 3A4.
Topics: Biotransformation; Catalysis; Catechols; Chromatography, High Pressure Liquid; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Erythromycin; Etoposide; Humans; Methylation; Microsomes, Liver; Midazolam; Mixed Function Oxygenases; Teniposide | 1994 |
A prescreening system for potential antiproliferative agents: implications for local treatment strategies of postangioplasty restenosis.
Topics: Actins; Adult; Aged; Aged, 80 and over; Angioplasty, Balloon; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Arteriosclerosis; Cell Division; Cells, Cultured; Colchicine; Cyclosporine; Dalteparin; Doxorubicin; Drug Evaluation, Preclinical; Etoposide; Female; Femoral Artery; Fibrinolytic Agents; Gout Suppressants; Humans; Immunosuppressive Agents; Male; Microtubules; Middle Aged; Muscle, Smooth, Vascular; Recurrence; Vimentin | 1995 |
Modulation effects of cyclosporine on etoposide pharmacokinetics and CNS distribution in the rat utilizing microdialysis.
Topics: Animals; Central Nervous System; Cyclosporine; Etoposide; Male; Microdialysis; Radioligand Assay; Rats; Rats, Sprague-Dawley | 1996 |
Cytokine network in peripheral blood mononuclear cells after allogeneic bone marrow transplantation.
Topics: Bone Marrow Transplantation; Cyclophosphamide; Cyclosporine; Cytokines; Etoposide; Gene Expression; Graft vs Host Disease; Histocompatibility Testing; Humans; Immunosuppressive Agents; Interleukins; Lymphocytes; Methotrexate; Polymerase Chain Reaction; RNA, Messenger; Transplantation, Homologous; Whole-Body Irradiation | 1996 |
Down-regulation of apoptosis-related bcl-2 but not bcl-xL or bax proteins in multidrug-resistant MCF-7/Adr human breast cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Base Sequence; bcl-2-Associated X Protein; bcl-X Protein; Breast Neoplasms; Cyclosporine; Doxorubicin; Drug Resistance, Multiple; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Molecular Sequence Data; Paclitaxel; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; Tumor Cells, Cultured; Verapamil; Vincristine | 1996 |
Epstein-Barr virus associated Burkitt lymphoma in a heart transplant recipient.
Topics: Allopurinol; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Burkitt Lymphoma; Cyclophosphamide; Cyclosporine; Cytarabine; Doxorubicin; Etoposide; Heart Transplantation; Herpesviridae Infections; Herpesvirus 4, Human; Humans; Immunocompromised Host; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Postoperative Complications; Prednisolone; Remission Induction; T-Lymphocytes, Cytotoxic; Tumor Virus Infections; Vincristine | 1996 |
Successful treatment of lymphomatoid granulomatosis using cyclosporin-A after failure of intensive chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; CD4-Positive T-Lymphocytes; Combined Modality Therapy; Cyclophosphamide; Cyclosporine; Doxorubicin; Etoposide; Humans; Immunosuppressive Agents; Lung Diseases; Lymphomatoid Granulomatosis; Male; Mechlorethamine; Methotrexate; Middle Aged; Prednisone; Procarbazine; Recurrence; Remission Induction; Salvage Therapy; Vincristine | 1996 |
Microdialysis assessment of microfibrous collagen containing a P-glycoprotein-mediated transport inhibitor, cyclosporine A, for local delivery of etoposide.
Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biliary Tract; Biological Transport; Blood Proteins; Collagen; Cyclosporine; Drug Carriers; Drug Interactions; Etoposide; Extracellular Space; Liver; Male; Microdialysis; Protein Binding; Rats; Rats, Wistar | 1996 |
Superiority of cyclosporin A over PSC-833 in enhancement of VP-16 efficacy in murine tumors in vivo.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cyclosporine; Cyclosporins; Drug Synergism; Etoposide; Female; Immunosuppressive Agents; Leukemia L1210; Lung Neoplasms; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Survival Rate; Time Factors | 1997 |
Chemosensitization and drug accumulation effects of VX-710, verapamil, cyclosporin A, MS-209 and GF120918 in multidrug resistant HL60/ADR cells expressing the multidrug resistance-associated protein MRP.
Topics: Acridines; Affinity Labels; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Cyclosporine; Daunorubicin; Doxorubicin; Drug Resistance, Multiple; Etoposide; Fluoresceins; HL-60 Cells; Humans; Isoquinolines; Multidrug Resistance-Associated Proteins; Piperidines; Pyridines; Quinolines; Tetrahydroisoquinolines; Tritium; Verapamil; Vincristine | 1997 |
Successful correction of hemophagocytic lymphohistiocytosis with related or unrelated bone marrow transplantation.
Topics: Adrenal Cortex Hormones; Bone Marrow Transplantation; Child, Preschool; Combined Modality Therapy; Cyclosporine; Etoposide; Female; Graft vs Host Disease; Histiocytosis, Non-Langerhans-Cell; Humans; Immunosuppressive Agents; Infant; Injections, Spinal; Killer Cells, Natural; Male; Methotrexate; Remission Induction; Survival Analysis; Transplantation Conditioning; Transplantation, Autologous; Transplantation, Homologous; Treatment Outcome | 1997 |
Reversal activity of cyclosporin A and its metabolites M1, M17 and M21 in multidrug-resistant cells.
Topics: Affinity Labels; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Cell Membrane; Chromatography, High Pressure Liquid; Cyclosporine; Dihydropyridines; Doxorubicin; Drug Interactions; Drug Resistance, Multiple; Etoposide; Humans; Hydroxylation; Kinetics; Methylation; Molecular Structure; Paclitaxel; Photochemistry; Tumor Cells, Cultured | 1997 |
The CD95 (APO-1/Fas) system mediates drug-induced apoptosis in neuroblastoma cells.
Topics: Antineoplastic Agents; Apoptosis; Cisplatin; Cyclosporine; Cysteine Endopeptidases; DNA Fragmentation; Doxorubicin; Drug Resistance, Neoplasm; Enzyme Activation; Etoposide; Fas Ligand Protein; fas Receptor; Humans; Immunoglobulin Fragments; Immunosuppressive Agents; Membrane Glycoproteins; Neuroblastoma; RNA, Messenger; Tumor Cells, Cultured; Up-Regulation | 1997 |
Interaction of cyclosporin A and etoposide. Clinical and in vitro assessment in blast phase of chronic myeloid leukaemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Cyclosporine; Drug Interactions; Etoposide; Humans; Immunosuppressive Agents; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male | 1997 |
Effect on cell kill of addition of multidrug resistance modifiers cyclosporin A and PSC 833 to cytotoxic agents in acute myeloid leukaemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Survival; Coloring Agents; Cyclosporine; Cyclosporins; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Drug Synergism; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1997 |
Clinical approach to circumvention of multidrug resistance in refractory leukemic patients: association of cyclosporin A with etoposide.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blast Crisis; Child; Cyclosporine; Drug Resistance, Multiple; Etoposide; Female; Growth Inhibitors; Humans; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured | 1997 |
Multidrug resistance modulation in rhabdomyosarcoma and neuroblastoma cell lines.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Small Cell; Cell Survival; Cisplatin; Cyclophosphamide; Cyclosporine; Doxorubicin; Drug Resistance, Multiple; Etoposide; Humans; Kinetics; Lung Neoplasms; Methotrexate; Neuroblastoma; Rhabdomyosarcoma; Time Factors; Tumor Cells, Cultured; Verapamil; Vincristine | 1998 |
[Hemophagocytic syndrome].
Topics: Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Blood Cell Count; Bone Marrow Transplantation; Chickenpox; Child, Preschool; Combined Modality Therapy; Cyclosporine; Dexamethasone; Drug Therapy, Combination; Etoposide; Histiocytosis, Non-Langerhans-Cell; Humans; Immunosuppressive Agents; Male; Multiple Organ Failure; Treatment Outcome | 1997 |
Effects of P-glycoprotein modulators on etoposide elimination and central nervous system distribution.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Brain; Cyclosporine; Etoposide; Frontal Lobe; Male; Rats; Rats, Sprague-Dawley; Sodium Cyanide; Tamoxifen; Trifluoperazine | 1998 |
High-dose chemotherapy with autologous hematopoietic progenitor cell transplantation in children with high-risk NHL and ALL-preliminary results.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Child, Preschool; Cyclosporine; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Lymphoma, Non-Hodgkin; Male; Platelet Count; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Survival Rate; Transplantation, Autologous; Treatment Outcome | 1998 |
Mitoxantrone, etoposide, and cytarabine plus cyclosporine for patients with relapsed or refractory acute myeloid leukemia: an Eastern Cooperative Oncology Group pilot study.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Cytarabine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Female; Gene Expression Regulation, Neoplastic; Genes, MDR; Humans; Leukemia, Myeloid; Leukopenia; Liver; Male; Middle Aged; Mitoxantrone; Recurrence; Remission Induction; Survival Rate; Treatment Outcome | 1999 |
Effective control of Epstein-Barr virus-related hemophagocytic lymphohistiocytosis with immunochemotherapy. Histiocyte Society.
Topics: Child; Child, Preschool; Cyclosporine; Dexamethasone; DNA, Viral; Epstein-Barr Virus Infections; Etoposide; Female; Glucocorticoids; Herpesvirus 4, Human; Histiocytosis, Non-Langerhans-Cell; Humans; Immunoglobulins, Intravenous; Immunosuppressive Agents; Infant; Male; Prednisolone; Remission Induction; Steroids | 1999 |
The proapoptotic effect of hepatitis B virus HBx protein correlates with its transactivation activity in stably transfected cell lines.
Topics: Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cell Line; Cyclosporine; DNA Repair; Etoposide; Hepatitis B Antigens; Humans; Mutation; Protein Kinases; Recombinant Proteins; Trans-Activators; Transcriptional Activation; Transfection; Viral Regulatory and Accessory Proteins | 1999 |
A case of hemophagocytic lymphohistiocytosis with prolonged remission after syngeneic bone marrow transplantation.
Topics: Bone Marrow Cells; Bone Marrow Transplantation; Child; Combined Modality Therapy; Cyclosporine; Dexamethasone; Drug Therapy, Combination; Etoposide; Female; gamma-Globulins; Granulocyte Colony-Stimulating Factor; Herpesvirus 4, Human; Histiocytosis, Non-Langerhans-Cell; Humans; Lymphocytes; Prednisolone; Recombinant Proteins; Transplantation, Isogeneic; Twins, Dizygotic | 1999 |
Cyclosporine-induced autologous graft-versus-host disease in patients with acute myeloid leukemia undergoing non-myeloablative chemotherapy without progenitor cell reinfusion.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Cyclophosphamide; Cyclosporine; Etoposide; Female; Graft vs Host Disease; Humans; Immunosuppressive Agents; Interferon-gamma; Killer Cells, Natural; Leukemia, Myeloid, Acute; Male; Middle Aged; Skin; T-Lymphocyte Subsets | 1999 |
Induction of mitochondrial permeability transition and cytochrome C release in the absence of caspase activation is insufficient for effective apoptosis in human leukemia cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Biological Transport; Caspase Inhibitors; Caspases; Cyclosporine; Cytochrome c Group; Cytosol; Enzyme Activation; Enzyme Inhibitors; Etoposide; Fluorescence; HL-60 Cells; Humans; Intracellular Membranes; Melanoma; Mitochondria; Mitochondria, Liver; Neoplasm Proteins; Oligopeptides; Permeability; Photochemistry; Pyrimidinones; Radiation-Sensitizing Agents; Rats; Rats, Wistar; Signal Transduction; Skin Neoplasms; Staurosporine; Tumor Cells, Cultured | 2000 |
Assessment of systemic toxicity in children receiving chemotherapy with cyclosporine for sarcoma.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood Transfusion; Chi-Square Distribution; Child; Child, Preschool; Cyclophosphamide; Cyclosporine; Dactinomycin; Etoposide; Female; Fever; Humans; Ifosfamide; Male; Neutropenia; Pilot Projects; Platelet Transfusion; Retrospective Studies; Sarcoma; Sepsis; Treatment Outcome; Vincristine | 2000 |
Complications of systemic chemotherapy as treatment of retinoblastoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Preschool; Cyclosporine; Cytarabine; Etoposide; Female; Fever; Humans; Infant; Male; Methotrexate; Neutropenia; Organophosphorus Compounds; Retinal Neoplasms; Retinoblastoma; Thrombocytopenia; Vincristine | 2000 |
Successful treatment of angioimmunoblastic lymphadenopathy with dysproteinemia-type T-cell lymphoma by combined methotrexate and prednisone.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Cyclosporine; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Humans; Immunoblastic Lymphadenopathy; Immunosuppressive Agents; Lymphoma, T-Cell, Peripheral; Male; Methotrexate; Prednisone; Remission Induction; Vincristine | 2000 |
Epoch-cyclosporin A induces high response rates in relapsed lymphomas.
Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cyclosporine; Disease-Free Survival; Doxorubicin; Drug Resistance, Multiple; Etoposide; Female; Humans; Lymphoma; Male; Pilot Projects; Prednisone; Recurrence; Treatment Outcome; Vincristine | 2000 |
Tumor-induced apoptosis of T cells: amplification by a mitochondrial cascade.
Topics: Anti-Bacterial Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; BH3 Interacting Domain Death Agonist Protein; Blotting, Western; Bongkrekic Acid; Carbocyanines; Carcinoma, Squamous Cell; Carrier Proteins; Caspase 9; Caspases; Coculture Techniques; Cyclosporine; Cytochrome c Group; Cytosol; DNA; Enzyme Activation; Enzyme Inhibitors; Etoposide; fas Receptor; Fluorescent Antibody Technique; Fluorescent Dyes; Head and Neck Neoplasms; Humans; Jurkat Cells; Lymphocytes; Microscopy, Fluorescence; Mitochondria; Oligopeptides; Protein Transport; Subcellular Fractions; T-Lymphocytes; Tumor Cells, Cultured | 2000 |
The levels of cdk5 and p35 proteins and tau phosphorylation are reduced during neuronal apoptosis.
Topics: Aldehydes; Animals; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cells, Cultured; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Cyclosporine; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Etoposide; Hippocampus; Nerve Tissue Proteins; Neurons; Nucleic Acid Synthesis Inhibitors; Okadaic Acid; Phosphorylation; Phosphotransferases; Rats; Rats, Wistar; tau Proteins; Time Factors | 2001 |
Requirement for etoposide in the treatment of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis.
Topics: Adolescent; Adult; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclosporine; Epstein-Barr Virus Infections; Etoposide; Female; Histiocytosis, Non-Langerhans-Cell; Humans; Infant; Male; Risk Factors; Survival Analysis; Treatment Outcome | 2001 |
CD14(dim)/CD16(bright) monocytes in hemophagocytic lymphohistiocytosis.
Topics: Adolescent; Cell Count; Cyclosporine; Dexamethasone; Etoposide; Histiocytosis, Non-Langerhans-Cell; HLA-DR Antigens; Humans; Immunosuppressive Agents; Lipopolysaccharide Receptors; Macrophage-1 Antigen; Male; Monocytes; Receptors, Complement 3b; Receptors, IgG | 2001 |
In vitro induction of apoptosis for nasal angiocentric natural killer cell lymphoma-derived cell line, NK-YS, by etoposide and cyclosporine A.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Cyclosporine; Drug Resistance, Neoplasm; Etoposide; Herpesvirus 4, Human; Humans; Immunosuppressive Agents; Killer Cells, Natural; Lymphoma, T-Cell; Nucleic Acid Synthesis Inhibitors; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2001 |
Secondary acute myelocytic leukemia after successful chemotherapy with etoposide for Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis.
Topics: Antineoplastic Agents, Phytogenic; Child, Preschool; Cyclosporine; Dexamethasone; Epstein-Barr Virus Infections; Etoposide; Female; Histiocytosis, Non-Langerhans-Cell; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Neoplasms, Second Primary | 2001 |
Enhancement of leukemia rejection by mice successfully treated for L1210 leukemia due to low dose compared to high dose VP-16.
Topics: Animals; Antineoplastic Agents, Phytogenic; Concanavalin A; Cyclosporine; Cyclosporins; Drug Screening Assays, Antitumor; Etoposide; Graft Rejection; Immunosuppressive Agents; Leukemia L1210; Lymphocyte Activation; Mice; Mice, Inbred DBA; Neoplasm Transplantation; Phytohemagglutinins | 2002 |
Intravenous immunoglobulin for hemophagocytic lymphohistiocytosis?
Topics: Adolescent; Adult; Antineoplastic Agents; Child; Clinical Trials as Topic; Cyclosporine; Drug Administration Schedule; Epstein-Barr Virus Infections; Etoposide; Histiocytosis, Non-Langerhans-Cell; Humans; Immunoglobulins, Intravenous; Immunosuppressive Agents; Macrophage Activation; Patient Selection; Reproducibility of Results | 2002 |
Standard versus alternative myeloablative conditioning regimens in allogeneic hematopoietic stem cell transplantation for high-risk acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Busulfan; Child; Child, Preschool; Cyclophosphamide; Cyclosporine; Cytarabine; Disease-Free Survival; Etoposide; Female; Graft Survival; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Immunosuppressive Agents; Infant; Leukemia; Life Tables; Male; Methylprednisolone; Middle Aged; Premedication; Retrospective Studies; Risk; Survival Analysis; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Whole-Body Irradiation | 2002 |
The toxicity and efficacy of donor lymphocyte infusions given after reduced-intensity conditioning allogeneic stem cell transplantation.
Topics: Adult; Aged; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Carmustine; Cyclosporine; Cytarabine; Data Collection; Etoposide; Female; Follow-Up Studies; Graft Enhancement, Immunologic; Graft Survival; Graft vs Host Disease; Hematologic Neoplasms; Humans; Immunosuppressive Agents; Lymphocyte Transfusion; Male; Melphalan; Middle Aged; Peripheral Blood Stem Cell Transplantation; Remission Induction; Transplantation Chimera; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Vidarabine | 2002 |
EVE/cyclosporin (etoposide, vincristine, epirubicin with high-dose cyclosporin)-chemotherapy selected for multidrug resistance modulation.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclosporine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Epirubicin; Etoposide; Female; Gastrointestinal Diseases; Heart Diseases; Hematologic Diseases; Humans; Kidney Diseases; Male; Neoplasms; Vincristine | 2002 |
Induction of complete remission of hypoplastic leukemia with antithymocyte globulin.
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Apoptosis; Bone Marrow Examination; Cyclosporine; Diagnosis, Differential; Etoposide; Humans; Leukemia; Male; Pancytopenia; Recurrence; Remission Induction | 2003 |
Effect of cyclosporine A on the tissue distribution and pharmacokinetics of etoposide.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cyclosporine; Drug Interactions; Etoposide; Immunosuppressive Agents; Infusions, Intravenous; Injections, Intravenous; Male; Rats; Rats, Wistar; Tissue Distribution | 2004 |
Successful control of Epstein-Barr virus (EBV)-infected cells by allogeneic nonmyeloablative stem cell transplantation in a patient with the lethal form of chronic active EBV infection.
Topics: Adolescent; B-Lymphocytes; Cell Line, Transformed; Cell Transformation, Viral; Chronic Disease; Cyclosporine; DNA, Viral; Drug Resistance; Epstein-Barr Virus Infections; Etoposide; Female; Hepatitis, Viral, Human; Herpesvirus 4, Human; Humans; Immunosuppressive Agents; Multiple Organ Failure; Peripheral Blood Stem Cell Transplantation; T-Lymphocytes, Cytotoxic; Tacrolimus; Transplantation Conditioning; Transplantation, Homologous | 2004 |
[Pathophysiology of and therapy for hemophagocytic syndrome].
Topics: Cyclosporine; Cytokines; Diagnosis, Differential; Drug Therapy, Combination; Etoposide; Hematopoietic Stem Cell Transplantation; Histiocytosis, Non-Langerhans-Cell; Humans; Macrophages; Plasma Exchange; Prednisolone; Prognosis; T-Lymphocytes | 2004 |
Fever and rash complicating osteomyelitis.
Topics: Anti-Bacterial Agents; Antineoplastic Agents, Phytogenic; Child; Community-Acquired Infections; Cyclosporine; Dexamethasone; Enzyme Inhibitors; Etoposide; Exanthema; Fever; Glucocorticoids; Histiocytosis, Non-Langerhans-Cell; Humans; Male; Osteomyelitis; Radiography | 2004 |
Docosahexaenoic acid induces apoptosis via the Bax-independent pathway in HL-60 cells.
Topics: Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspases; Cyclosporine; Docosahexaenoic Acids; Enzyme Activation; Etoposide; HL-60 Cells; Humans; Mitochondria; Permeability; Protein Transport; Proto-Oncogene Proteins c-bcl-2 | 2004 |
Hemophagocytic lymphohistiocytosis after chemotherapy for multiple myeloma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Bone Marrow; Cyclosporine; Dexamethasone; Etoposide; Histiocytosis, Non-Langerhans-Cell; Humans; Male; Middle Aged; Multiple Myeloma; Treatment Outcome | 2004 |
Haemophagocytic lymphohistiocytosis in Malaysian children.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child, Preschool; Cyclosporine; Dexamethasone; Etoposide; Female; Histiocytosis, Non-Langerhans-Cell; Humans; Immunosuppressive Agents; Malaysia; Male | 2005 |
Successful treatment of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis with HLH-94 protocol.
Topics: Adolescent; Bone Marrow Transplantation; Child, Preschool; Cyclosporine; Dexamethasone; Drug Therapy, Combination; Epstein-Barr Virus Infections; Etoposide; Female; Histiocytosis, Non-Langerhans-Cell; Humans; Male | 2005 |
Effect of particle size of nanospheres and microspheres on the cellular-association and cytotoxicity of paclitaxel in 4T1 cells.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Boron Compounds; Brain; Cattle; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Cyclosporine; Deoxyglucose; Drug Screening Assays, Antitumor; Endocytosis; Endothelium, Vascular; Etoposide; Lactic Acid; Microspheres; Nanotubes; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers | 2005 |
The p53-induced gene-6 (proline oxidase) mediates apoptosis through a calcineurin-dependent pathway.
Topics: Apoptosis; Blotting, Western; Calcineurin; Calcium; Carcinoma, Renal Cell; Cell Line, Tumor; Cyclosporine; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Etoposide; Genes, Reporter; Green Fluorescent Proteins; Humans; Kidney Neoplasms; Luciferases; NFATC Transcription Factors; Nuclear Proteins; Nucleic Acid Synthesis Inhibitors; Oligonucleotides, Antisense; Plasmids; Proline Oxidase; Reactive Oxygen Species; Tacrolimus; Transcription Factors; Transfection; Tumor Suppressor Protein p53; Up-Regulation | 2005 |
Haematopoietic stem cell transplantation in haemophagocytic lymphohistiocytosis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cyclosporine; Dexamethasone; Disease-Free Survival; Etoposide; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Histiocytosis, Non-Langerhans-Cell; Humans; Immunophenotyping; Infant; Male; Methotrexate; Odds Ratio; Regression Analysis; Reoperation; Tissue Donors; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome | 2005 |
Post-transplantation lymphoproliferative disorder of recipient origin in a boy with acute T-cell leukemia with detection of B-cell clonality 3 months before stem cell transplantation.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; B-Lymphocytes; Child; Clone Cells; Combined Modality Therapy; Cyclophosphamide; Cyclosporine; Cytarabine; Daunorubicin; Dexamethasone; Epstein-Barr Virus Infections; Etoposide; Fatal Outcome; Glucocorticoids; Graft vs Host Disease; Herpesvirus 4, Human; Humans; Immunosuppressive Agents; Leukemia-Lymphoma, Adult T-Cell; Lymphocyte Transfusion; Lymphoproliferative Disorders; Male; Postoperative Complications; Prednisolone; Rituximab; Time Factors; Transplantation Chimera; Transplantation Conditioning; Vincristine; Virus Activation; Whole-Body Irradiation | 2005 |
The course of etoposide-induced apoptosis in Jurkat cells lacking p53 and Bax.
Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; BH3 Interacting Domain Death Agonist Protein; Caspase Inhibitors; Caspases; Cyclosporine; Cytochromes c; DNA Damage; DNA-Binding Proteins; DNA, Neoplasm; Enzyme Activation; Etoposide; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Jurkat Cells; Mitochondria; Mitochondrial Membranes; Mitochondrial Swelling; Nuclear Proteins; Phosphorylation; Proto-Oncogene Proteins c-abl; Proto-Oncogene Proteins c-bcl-2; T-Lymphocytes; Tumor Protein p73; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2006 |
Induction of necrotic cell death and mitochondrial permeabilization by heme binding protein 2/SOUL.
Topics: Animals; Antineoplastic Agents, Phytogenic; Calcimycin; Calcium; Carrier Proteins; Cyclosporine; Etoposide; Heme-Binding Proteins; Hemeproteins; Humans; Immunosuppressive Agents; Ionophores; Mice; Mitochondria; Mitochondrial Membranes; Necrosis; NIH 3T3 Cells; Permeability; Pregnancy Proteins; Recombinant Proteins | 2006 |
Cyclosporin in subcutaneous panniculitis-like T-cell lymphoma.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Cyclosporine; Cytarabine; Doxorubicin; Etoposide; Female; Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor; Humans; Immunosuppressive Agents; Lymphoma, T-Cell, Cutaneous; Male; Methylprednisolone; Middle Aged; Panniculitis; Prednisone; Prognosis; Remission Induction; Skin Neoplasms; Treatment Outcome; Vincristine | 2007 |
Regression of the tumor after withdrawal of cyclosporine in relapsed extranodal natural killer/T cell lymphoma following allogeneic hematopoietic stem cell transplantation.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Combined Modality Therapy; Cryptogenic Organizing Pneumonia; Cyclophosphamide; Cyclosporine; Cytarabine; Dexamethasone; Doxorubicin; Etoposide; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Ifosfamide; Immunosuppressive Agents; Lymphoma, T-Cell, Peripheral; Methotrexate; Neoplasm Recurrence, Local; Palatal Neoplasms; Remission Induction; Salvage Therapy; Transplantation, Homologous; Vincristine | 2007 |
Nonfamilial hemophagocytic lymphohistiocytosis.
Topics: Adult; Cyclosporine; Dexamethasone; Drug Therapy, Combination; Etoposide; Humans; Kupffer Cells; Liver; Lymphohistiocytosis, Hemophagocytic; Male; Splenomegaly; Tomography, X-Ray Computed | 2007 |
Cyclosporin A inhibits HTLV-I tax expression and shows anti-tumor effects in combination with VP-16.
Topics: Antineoplastic Agents; Apoptosis; Cell Line; Cell Line, Tumor; Cyclosporine; Dose-Response Relationship, Drug; Etoposide; Gene Expression Regulation, Viral; Gene Products, tax; Herpes Simplex Virus Protein Vmw65; Human T-lymphotropic virus 1; Humans | 2007 |
Neuroprotective role of antidiabetic drug metformin against apoptotic cell death in primary cortical neurons.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cells, Cultured; Cerebral Cortex; Cyclosporine; Cytochromes c; Diabetic Neuropathies; Enzyme Inhibitors; Etoposide; Hypoglycemic Agents; Membrane Potential, Mitochondrial; Metformin; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar | 2008 |
Experience with hemophagocytic lymphohistiocytosis/macrophage activation syndrome at a single institution.
Topics: Adolescent; Adrenal Cortex Hormones; Cause of Death; Child; Child, Preschool; Cyclosporine; Etoposide; Female; Hematologic Neoplasms; Humans; Immunoglobulins, Intravenous; Infant; Lymphohistiocytosis, Hemophagocytic; Macrophage Activation Syndrome; Male; Retrospective Studies; Rheumatic Diseases; Steroids; Virus Diseases | 2009 |
Characteristics of hemophagocytic lymphohistiocytosis in neonates: a nationwide survey in Japan.
Topics: Acyclovir; Adrenal Cortex Hormones; Antineoplastic Agents, Phytogenic; Antiviral Agents; beta 2-Microglobulin; Consciousness Disorders; Cyclosporine; Erythema; Etoposide; Exanthema; Female; Fetal Distress; Fever; gamma-Globulins; Hematopoietic Stem Cell Transplantation; Herpes Simplex; Humans; Immunologic Factors; Immunosuppressive Agents; Infant, Newborn; Infant, Premature; Japan; L-Lactate Dehydrogenase; Leukocytosis; Lymphohistiocytosis, Hemophagocytic; Male; Ocular Motility Disorders; Plasma Exchange; Prognosis; Respiratory Distress Syndrome, Newborn; Seizures; Severe Combined Immunodeficiency | 2009 |
Cytotoxicity and mitochondrial apoptosis induced by etoposide in melanoma cells.
Topics: Adenosine Triphosphate; Antineoplastic Agents, Phytogenic; Apoptosis; Ataxia Telangiectasia Mutated Proteins; bcl-2-Associated X Protein; Benzothiazoles; Caspase 2; Caspase 3; Caspase 9; Caspase Inhibitors; Cell Cycle Proteins; Cyclosporine; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA Damage; DNA-Binding Proteins; Etoposide; Humans; Melanoma; Mitochondria; Neoplasm Proteins; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Superoxides; Toluene; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2009 |
Retinoma underlying retinoblastoma revealed after tumor response to 1 cycle of chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Calcinosis; Carboplatin; Child, Preschool; Cyclosporine; Etoposide; Eye Enucleation; Humans; Male; Retinal Diseases; Retinal Neoplasms; Retinoblastoma; Vincristine | 2009 |
Dermatopathic lymphadenitis with generalized erythroderma in a patient with epstein-barr virus-associated hemophagocytic lymphohistiocytosis.
Topics: Anti-Inflammatory Agents; Antineoplastic Combined Chemotherapy Protocols; Cyclosporine; Dermatitis, Exfoliative; Dexamethasone; Epstein-Barr Virus Infections; Etoposide; Female; Humans; Lymphadenitis; Lymphohistiocytosis, Hemophagocytic; Middle Aged | 2010 |
Etoposide induces more severe mucositis than CY when added to TBI as conditioning in allograft recipients receiving CsA and MTX.
Topics: Adolescent; Adult; Antineoplastic Agents, Phytogenic; Cyclophosphamide; Cyclosporine; Drug Therapy, Combination; Etoposide; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Leukemia; Male; Methotrexate; Middle Aged; Mucositis; Retrospective Studies; Severity of Illness Index; Transplantation Conditioning; Transplantation, Homologous; Whole-Body Irradiation; Young Adult | 2010 |
Etoposide-related cardiotoxicity in a child with haemophagocytic lymphohistiocytosis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Cyclosporine; Electrocardiography; Etoposide; Follow-Up Studies; Humans; Lymphohistiocytosis, Hemophagocytic; Male; Myocardial Infarction; Risk Assessment; Steroids; Ventricular Remodeling; Withholding Treatment | 2010 |
Microbiological findings and treatment of EBV-associated hemophagocytic lymphohistiocytosis: a case report.
Topics: Adolescent; Bone Marrow; Cyclosporine; DNA, Viral; Drug Therapy, Combination; Epstein-Barr Virus Infections; Etoposide; Fever; Herpesvirus 4, Human; Humans; Immunophenotyping; Lymphatic Diseases; Lymphohistiocytosis, Hemophagocytic; Male; Skin; Skin Ulcer; Steroids | 2010 |
[28-year old female patient with respiratory insufficiency, elevated liver enzymes, pancytopenia and fever].
Topics: Adult; Antiviral Agents; Bone Marrow Examination; Cyclosporine; Cytokines; Cytomegalovirus Infections; Diagnosis, Differential; Drug Therapy, Combination; Etoposide; Female; Ferritins; Fever of Unknown Origin; Ganciclovir; Humans; Immunosuppressive Agents; Liver Function Tests; Lymphohistiocytosis, Hemophagocytic; Pancytopenia; Pneumonia, Viral; Prednisone; Respiratory Insufficiency; Tomography, X-Ray Computed | 2010 |
Ophthalmic vasculature alterations following systemic chemotherapy and periocular Carboplatin treatment of advanced retinoblastoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Chemotherapy, Cancer, Regional Perfusion; Child, Preschool; Combined Modality Therapy; Cyclosporine; Etoposide; Female; Fluorescein Angiography; Humans; Infant; Injections, Intra-Arterial; Laser Coagulation; Ophthalmic Artery; Retinal Artery; Retinal Neoplasms; Retinoblastoma; Sclerosis; Vincristine | 2010 |
Treatment of Epstein-Barr virus-related hemophagocytic lymphohistiocytosis (EBV-HLH); update 2010.
Topics: Adrenal Cortex Hormones; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Cyclosporine; Epstein-Barr Virus Infections; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Immunoglobulins; Lymphohistiocytosis, Hemophagocytic; Neoplasm Staging; Risk Factors; Treatment Outcome | 2011 |
Acute promyelocytic leukemia following chemotherapy for EBV-associated hemophagocytic lymphohistiocytosis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Cyclosporine; Dexamethasone; Epstein-Barr Virus Infections; Etoposide; Herpesvirus 4, Human; Humans; In Situ Hybridization, Fluorescence; Infant; Karyotyping; Leukemia, Promyelocytic, Acute; Lymphatic Diseases; Lymphohistiocytosis, Hemophagocytic; Male; Oncogene Proteins, Fusion; Translocation, Genetic | 2011 |
Multifaceted chemotherapy for trilateral retinoblastoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Cyclosporine; Cytarabine; Etoposide; Fatal Outcome; Female; Humans; Infant; Magnetic Resonance Imaging; Male; Neoplasm Recurrence, Local; Neoplasms, Multiple Primary; Pineal Gland; Retinal Neoplasms; Retinoblastoma; Tomography, X-Ray Computed; Topotecan; Vincristine | 2011 |
Haemophagocytic lymphohistiocytosis: a case series from Mumbai.
Topics: Adolescent; Antineoplastic Agents; Child; Child, Preschool; Cyclosporine; Dexamethasone; Etoposide; Female; Humans; India; Infant; Lymphohistiocytosis, Hemophagocytic; Male; Methotrexate; Retrospective Studies | 2011 |
Risk factors for early death in children with haemophagocytic lymphohistiocytosis.
Topics: Adolescent; Anti-Inflammatory Agents; Child; Cyclosporine; Dexamethasone; Drug Therapy, Combination; Etoposide; Female; Ferritins; Fever; Humans; Hyperbilirubinemia; Immunosuppressive Agents; Leukocytosis; Lymphohistiocytosis, Hemophagocytic; Male; Prognosis; Proportional Hazards Models; Risk Factors; Thrombocytopenia | 2012 |
Etoposide modulates the effects of oral morphine analgesia by targeting the intestinal P-glycoprotein.
Topics: Administration, Oral; Analgesics, Opioid; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cyclosporine; Disease Models, Animal; Drug Administration Schedule; Drug Interactions; Etoposide; Intestinal Mucosa; Male; Mice; Morphine; Pain; Rhodamine 123; Up-Regulation | 2012 |
Cytomegalovirus-induced haemophagocytic lymphohistiocytosis syndrome.
Topics: Cyclosporine; Cytomegalovirus Infections; Dexamethasone; Diagnosis, Differential; Drug Therapy, Combination; Etoposide; Female; Ganciclovir; Humans; Immunoglobulins, Intravenous; Lymphohistiocytosis, Hemophagocytic; Respiration, Artificial; Syndrome; Young Adult | 2012 |
Hyperferritinemia in the critically ill child with secondary hemophagocytic lymphohistiocytosis/sepsis/multiple organ dysfunction syndrome/macrophage activation syndrome: what is the treatment?
Topics: Adolescent; Antineoplastic Agents, Phytogenic; Child; Child, Preschool; Combined Modality Therapy; Critical Illness; Cyclosporine; Dexamethasone; Etoposide; Female; Ferritins; Glucocorticoids; Humans; Immunoglobulins, Intravenous; Immunosuppressive Agents; Iron Overload; Lymphohistiocytosis, Hemophagocytic; Macrophage Activation Syndrome; Male; Multiple Organ Failure; Plasma Exchange; Prednisolone; Regression Analysis; Sepsis; Survival Rate; Treatment Outcome; Turkey | 2012 |
Severe transient left ventricular pseudohypertrophy during treatment of hemophagocytic lymphohistiocytosis: a case report.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclosporine; Dexamethasone; Echocardiography; Electrocardiography; Etoposide; Humans; Hypertrophy, Left Ventricular; Infant; Lymphohistiocytosis, Hemophagocytic; Male; Prognosis | 2012 |
Sequential monitoring of serum IL-6, TNF-α, and IFN-γ levels in a CAEBV patient treated by plasma exchange and immunochemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chronic Disease; Cyclosporine; Disseminated Intravascular Coagulation; Epstein-Barr Virus Infections; Etoposide; Female; Herpesvirus 4, Human; Humans; Interferon-gamma; Interleukin-6; Lymphohistiocytosis, Hemophagocytic; Middle Aged; Plasma Exchange; Prednisolone; Tumor Necrosis Factor-alpha | 2012 |
Familial haemophagocytic lymphohistiocytosis in twin infants.
Topics: Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Cyclosporine; Dexamethasone; Diseases in Twins; Etoposide; Fatal Outcome; Humans; Immunosuppressive Agents; Infant; Lymphohistiocytosis, Hemophagocytic; Mutation; Treatment Outcome; Twins, Monozygotic | 2013 |
[Case report: a case of Epstein-Barr virus associated hemophagocytic syndrome with reversible leukoencephalopathy in the splenium of the corpus callosum].
Topics: Corpus Callosum; Cyclosporine; Dexamethasone; Epstein-Barr Virus Infections; Etoposide; Female; Humans; Leukoencephalopathies; Lymphohistiocytosis, Hemophagocytic; Methylprednisolone; Young Adult | 2013 |
Are regimens containing rituximab effective in the initial treatment of Epstein-Barr virus-positive natural killer cell lymphoproliferative disease-associated hemophagocytic lymphohistiocytosis?
Topics: Antibodies, Monoclonal, Murine-Derived; Cyclosporine; Drug Therapy, Combination; Etoposide; Humans; Immunologic Factors; Immunosuppressive Agents; Killer Cells, Natural; Lymphohistiocytosis, Hemophagocytic; Lymphoproliferative Disorders; Male; Middle Aged; Prednisolone; Rituximab; Time Factors | 2013 |
Two-faced haemophagocytic lymphohistiocytosis: comparative review of two cases of adult haemophagocytic lymphohistiocytosis.
Topics: Adult; Anti-Inflammatory Agents; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents, Phytogenic; Biopsy, Fine-Needle; Cyclosporine; Dexamethasone; Diagnosis, Differential; Epstein-Barr Virus Infections; Etoposide; Female; Histiocytes; Humans; Immunoglobulins, Intravenous; Immunologic Factors; Lymphohistiocytosis, Hemophagocytic; Lymphoma, T-Cell; Male; Middle Aged; Rituximab; Tomography, X-Ray Computed; Treatment Outcome | 2014 |
Profile of hemophagocytic lymphohistiocytosis; efficacy of intravenous immunoglobulin therapy.
Topics: Antineoplastic Agents, Phytogenic; Child; Child, Preschool; Cohort Studies; Cyclosporine; Dexamethasone; Drug Therapy, Combination; Etoposide; Female; Ferritins; Humans; Immunoglobulins, Intravenous; Immunosuppressive Agents; Infant; Lymphohistiocytosis, Hemophagocytic; Male; Retrospective Studies; Treatment Outcome | 2014 |
Clinical features, treatment, and outcome of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis: a multinational, multicenter study of 362 patients.
Topics: Adrenal Cortex Hormones; Arthritis, Juvenile; Biological Products; Child; Child, Preschool; Cohort Studies; Cyclosporine; Etoposide; Female; Fever; Hepatomegaly; Humans; Intensive Care Units; International Cooperation; Macrophage Activation Syndrome; Male; Prevalence; Retrospective Studies; Splenomegaly; Survival Rate; Treatment Outcome | 2014 |
Familial haemophagocytic lymphohistiocytosis: Australian experience and perspectives.
Topics: Antibodies, Monoclonal, Murine-Derived; Cyclosporine; Dexamethasone; Epstein-Barr Virus Infections; Etoposide; Female; Humans; Lymphohistiocytosis, Hemophagocytic; Lymphoma, T-Cell; Male | 2014 |
Haemophagocytic lymphohistiocytosis: from diagnostic challenges to predictive possibilities.
Topics: Cyclosporine; Cytokines; Dexamethasone; Etoposide; Humans; Immunoglobulins, Intravenous; Immunosuppressive Agents; Lymphohistiocytosis, Hemophagocytic; Plasma Exchange; Predictive Value of Tests; Topoisomerase II Inhibitors | 2015 |
Clinical characteristics and prognostic factors of adult hemophagocytic syndrome patients: a retrospective study of increasing awareness of a disease from a single-center in China.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Antineoplastic Agents; China; Cyclosporine; Etoposide; Female; Glucocorticoids; Health Knowledge, Attitudes, Practice; Herpesvirus 4, Human; Humans; Lymphohistiocytosis, Hemophagocytic; Lymphoma; Male; Middle Aged; Retrospective Studies; Young Adult | 2015 |
Effects of cyclosporine A on the hepatobiliary disposition and hepatic uptake of etoposide in an isolated perfused rat liver model.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cyclosporine; Drug Interactions; Etoposide; Hepatobiliary Elimination; Liver; Male; Perfusion; Rats | 2015 |
Assessment of modulated cytostatic drug resistance by automated γH2AX analysis.
Topics: Adult; Cyclosporine; Cytostatic Agents; DNA; DNA Breaks, Double-Stranded; Drug Resistance, Multiple; Etoposide; Female; Histones; Humans; Leukocytes, Mononuclear; Male; Microscopy, Fluorescence; Sirolimus; Young Adult | 2015 |
A Hemophagocytic Lymphohistiocytosis Case with Newly Defined UNC13D (c.175G>C; p.Ala59Pro) Mutation and a Rare Complication.
Topics: Amino Acid Substitution; Amphotericin B; Aspergillosis; Bone Marrow Transplantation; Combined Modality Therapy; Cyclosporine; Debridement; Dexamethasone; Drug Therapy, Combination; Etoposide; Female; Humans; Immunocompromised Host; Infant; Lymphohistiocytosis, Hemophagocytic; Membrane Proteins; Methotrexate; Mutation, Missense; Nasal Septal Perforation; Opportunistic Infections; Palate, Soft; Point Mutation; Stomatitis | 2015 |
Neurological presentation of hemophagocytic lymphohistiocytosis.
Topics: Antibodies, Viral; Blindness; Cyclosporine; Dexamethasone; DNA, Viral; Drug Therapy, Combination; Epistaxis; Etoposide; Herpesvirus 4, Human; Humans; Infectious Mononucleosis; Lymphohistiocytosis, Hemophagocytic; Magnetic Resonance Imaging; Male; Muscle Weakness; Postural Balance; Sensation Disorders; Young Adult | 2015 |
Treatment of hemophagocytic lymphohistiocytosis in adults.
Topics: Adult; Algorithms; Antineoplastic Agents; Clinical Trials as Topic; Cyclosporine; Dexamethasone; Etoposide; Hematology; Humans; Immunoglobulins, Intravenous; Immunosuppression Therapy; Influenza, Human; Lymphohistiocytosis, Hemophagocytic; Stem Cell Transplantation; T-Lymphocytes | 2015 |
Concomitant Presentation of Hemophagocytic Lymphohistiocytosis and Posttransplant Lymphoproliferative Disease-Like Lymphoma in a Mildly Immunosuppressed Leukemia Patient: An Unusual Association.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cyclosporine; Dexamethasone; Epstein-Barr Virus Infections; Etoposide; Female; Humans; Immunocompromised Host; Infant; Lymphohistiocytosis, Hemophagocytic; Male; Mercaptopurine; Methotrexate; Multiple Organ Failure; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Rituximab; Treatment Failure; Vincristine; Viral Load | 2016 |
Neonatal Haemophagocytic Lymphohistiocytosis Associated with Maternal Adult-Onset Still's Disease.
Topics: Cyclosporine; Etoposide; Female; Fever; Genetic Testing; Humans; Infant; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Lymphohistiocytosis, Hemophagocytic; Pregnancy; Pregnancy Complications; Prenatal Diagnosis; Still's Disease, Adult-Onset | 2016 |
Cytomegalovirus-Induced Hemophagocytic Lymphohistiocytosis in an Extreme Preterm Infant: Recognition and Therapy Leading to Recovery.
Topics: Antineoplastic Agents, Phytogenic; Antiviral Agents; Bone Marrow; Cyclosporine; Cytomegalovirus Infections; Dexamethasone; Etoposide; Ganciclovir; Glucocorticoids; Humans; Immunosuppressive Agents; Infant; Infant, Extremely Premature; Infant, Newborn; Killer Cells, Natural; Lymphohistiocytosis, Hemophagocytic; Male; Receptors, Interleukin-2; Treatment Outcome; Valganciclovir | 2017 |
Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis during pregnancy.
Topics: Adult; Cyclosporine; Epstein-Barr Virus Infections; Etoposide; Female; Humans; Infectious Mononucleosis; Lymphohistiocytosis, Hemophagocytic; Pregnancy; Treatment Outcome | 2017 |
Confirmed efficacy of etoposide and dexamethasone in HLH treatment: long-term results of the cooperative HLH-2004 study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclosporine; Dexamethasone; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Infant; Longitudinal Studies; Lymphohistiocytosis, Hemophagocytic; Male; Treatment Outcome | 2017 |
A rare and serious cause of pancytopenia in a patient with systemic lupus erythematosus: haemophagocytic lymphohistiocytosis.
Topics: Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Cyclosporine; Dexamethasone; Etoposide; Female; Ferritins; Humans; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Lymphohistiocytosis, Hemophagocytic; Middle Aged; Pancytopenia; Patient Comfort; Treatment Outcome | 2018 |
MRP2-mediated transport of etoposide in MDCKII MRP2 cells is unaffected by commonly used non-ionic surfactants.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biological Transport; Cyclosporine; Dogs; Etoposide; Madin Darby Canine Kidney Cells; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Surface-Active Agents | 2019 |
Atypical Chronic Myeloid Leukemia in a Patient with Aplastic Anemia.
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocols; Cyclosporine; Cytarabine; Etoposide; Fatal Outcome; Granulocyte Colony-Stimulating Factor; Humans; Imidazoles; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Methylprednisolone; Prednisolone; Pyridazines | 2019 |
Haemophagocytic lymphohistiocytosis in pregnancy.
Topics: Adult; Bone Marrow; Cyclosporine; Dexamethasone; Etoposide; Female; Glucocorticoids; Humans; Immunoglobulins, Intravenous; Immunosuppressive Agents; Lymphohistiocytosis, Hemophagocytic; Methylprednisolone; Pregnancy; Pregnancy Complications; Topoisomerase II Inhibitors; Young Adult | 2020 |
Treatment of pediatric primary hemophagocytic lymphohistiocytosis with the HLH-94/2004 regimens and hematopoietic stem cell transplantation in China.
Topics: Child; Child, Preschool; China; Combined Modality Therapy; Cyclosporine; Disease-Free Survival; Doxorubicin; Drug Therapy, Combination; Etoposide; Follow-Up Studies; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Infant; Infant, Newborn; Kaplan-Meier Estimate; Lymphohistiocytosis, Hemophagocytic; Methylprednisolone; Prognosis; Remission Induction; Retrospective Studies; Transplantation Conditioning; Treatment Outcome | 2020 |
Successful use of short-term add-on tocilizumab for refractory adult-onset still's disease with macrophage activation syndrome despite treatment with high-dose glucocorticoids, cyclosporine, and etoposide.
Topics: Antibodies, Monoclonal, Humanized; Cyclosporine; Drug Resistance; Drug Therapy, Combination; Etoposide; Glucocorticoids; Humans; Immunosuppressive Agents; Macrophage Activation Syndrome; Molecular Targeted Therapy; Severity of Illness Index; Still's Disease, Adult-Onset; Treatment Outcome | 2020 |
UNC13D mutation in a patient with juvenile polymyositis with recurrent macrophage activation syndrome.
Topics: Adolescent; Antirheumatic Agents; Autoantibodies; Bone Marrow Examination; Cyclosporine; Etoposide; Homozygote; Humans; Macrophage Activation Syndrome; Male; Membrane Proteins; Methylprednisolone; Mutation, Missense; Patient Care Planning; Polymyositis; Positron Emission Tomography Computed Tomography; Remission Induction; Topoisomerase II Inhibitors; Treatment Outcome | 2021 |
Spontaneous Recovery of Hemophagocytic Lymphohistiocytosis Due to Primary Epstein-Barr Virus Infection in an Adult Patient.
Topics: Adult; Child; Cyclosporine; Epstein-Barr Virus Infections; Etoposide; Herpesvirus 4, Human; Humans; Lymphohistiocytosis, Hemophagocytic; Male | 2021 |