Page last updated: 2024-08-23

etoposide and calpain

etoposide has been researched along with calpain in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (13.33)18.2507
2000's12 (80.00)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Droin, N; Eymin, B; Haugg, M; Munsch, B; Solary, E; Sordet, O; Van de Craen, M; Vandenabeele, P1
Lee, AS; Lu, J; Reddy, RK1
Dou, QP; Gao, G1
Benetti, R; Brancolini, C; Del Sal, G; Monte, M; Paroni, G; Schneider, C1
Radhika, G; Sarin, A; Varghese, J1
Kim, JI; Kook, S; Shim, SR; Song, WK1
Choi, WS; Chung, IK; Eom, DS; Han, BS; Kim, JE; Lee, EH; Lee, GE; Markelonis, GJ; Oh, TH; Oh, YJ; Saido, TC1
Hansson, J; Linder, S; Mandic, A; Shoshan, MC1
Chun, JS; Kim, DH; Kim, W; Kook, S; Shim, SR; Song, WK1
Cao, X; Deng, X; May, WS1
Anderson, JS; Daniel, KG; Dou, QP; Gupta, P; Kazi, A; Zhong, Q1
Karlsson, J; Påhlman, S; Pörn-Ares, I; Øra, I1
Brunner, T; Perozzo, R; Scapozza, L; Schaffner, T; Schmid, I; Simon, HU; Yousefi, S; Ziemiecki, A1
Pisalyaput, K; Tenner, AJ1
Berger, SA; Li, H; Martin, A; Nepal, RM1

Other Studies

15 other study(ies) available for etoposide and calpain

ArticleYear
Caspase-induced proteolysis of the cyclin-dependent kinase inhibitor p27Kip1 mediates its anti-apoptotic activity.
    Oncogene, 1999, Aug-26, Volume: 18, Issue:34

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Base Sequence; Calpain; Caspase 3; Caspase 6; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; CDC2-CDC28 Kinases; Cell Cycle Proteins; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cysteine Proteinase Inhibitors; Etoposide; Humans; Leukemia; Leupeptins; Microtubule-Associated Proteins; Molecular Sequence Data; Mutation; Nucleic Acid Synthesis Inhibitors; Oligopeptides; Protein Serine-Threonine Kinases; Thimerosal; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tumor Suppressor Proteins

1999
The endoplasmic reticulum chaperone glycoprotein GRP94 with Ca(2+)-binding and antiapoptotic properties is a novel proteolytic target of calpain during etoposide-induced apoptosis.
    The Journal of biological chemistry, 1999, Oct-01, Volume: 274, Issue:40

    Topics: Apoptosis; Calcium; Calpain; Cell Line; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Etoposide; HSP70 Heat-Shock Proteins; Humans; Hydrolysis; Membrane Proteins; Protein Binding; Tumor Cells, Cultured

1999
N-terminal cleavage of bax by calpain generates a potent proapoptotic 18-kDa fragment that promotes bcl-2-independent cytochrome C release and apoptotic cell death.
    Journal of cellular biochemistry, 2000, Sep-18, Volume: 80, Issue:1

    Topics: Apoptosis; Base Sequence; bcl-2-Associated X Protein; Calpain; Cytochrome c Group; Dipeptides; DNA Primers; Enzyme Activation; Etoposide; Humans; Hydrolysis; Jurkat Cells; Mitochondria; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2

2000
The death substrate Gas2 binds m-calpain and increases susceptibility to p53-dependent apoptosis.
    The EMBO journal, 2001, Jun-01, Volume: 20, Issue:11

    Topics: Animals; Apoptosis; Calpain; Cell Line; Cell Survival; Etoposide; Genes, Reporter; Humans; Luciferases; Methyl Methanesulfonate; Mice; Mice, Inbred BALB C; Microfilament Proteins; Osteosarcoma; Recombinant Proteins; Saccharomyces cerevisiae; Sequence Deletion; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Ultraviolet Rays

2001
The role of calpain in caspase activation during etoposide induced apoptosis in T cells.
    European journal of immunology, 2001, Volume: 31, Issue:7

    Topics: Animals; Apoptosis; Calpain; Caspases; Cysteine Proteinase Inhibitors; Dipeptides; Enzyme Activation; Etoposide; Fas Ligand Protein; Hybridomas; Leucine; Membrane Glycoproteins; Mice; T-Lymphocytes

2001
Degradation of focal adhesion proteins paxillin and p130cas by caspases or calpains in apoptotic rat-1 and L929 cells.
    Biochemical and biophysical research communications, 2001, Aug-24, Volume: 286, Issue:3

    Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Calpain; Caspase 3; Caspase Inhibitors; Caspases; Cell Line; Crk-Associated Substrate Protein; Cysteine Proteinase Inhibitors; Cytoskeletal Proteins; Etoposide; Fluorescent Antibody Technique; Focal Adhesions; Oligopeptides; Paxillin; Phosphoproteins; Proteins; Rats; Retinoblastoma-Like Protein p130; Tumor Cells, Cultured

2001
Temporospatial sequence of cellular events associated with etoposide-induced neuronal cell death: role of antiapoptotic protein Bcl-X(L).
    Journal of neuroscience research, 2001, Dec-15, Volume: 66, Issue:6

    Topics: Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Calpain; Carrier Proteins; Caspase Inhibitors; Caspases; Cell Nucleus; Cells, Cultured; Central Nervous System; Cytochrome c Group; DNA; DNA Topoisomerases, Type II; Enzyme Inhibitors; Etoposide; Humans; Microfilament Proteins; Neurons; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Subcellular Fractions; Time Factors; Topoisomerase II Inhibitors

2001
Cisplatin induces endoplasmic reticulum stress and nucleus-independent apoptotic signaling.
    The Journal of biological chemistry, 2003, Mar-14, Volume: 278, Issue:11

    Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Calcium; Calpain; Carrier Proteins; Caspase 3; Caspases; Cell Nucleus; Cisplatin; Cytosol; DNA Damage; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Enzyme Activation; Enzyme Inhibitors; Etoposide; Flow Cytometry; Heat-Shock Proteins; Humans; Molecular Chaperones; Time Factors; Tumor Cells, Cultured

2003
Caspase-dependent cleavage of tensin induces disruption of actin cytoskeleton during apoptosis.
    Biochemical and biophysical research communications, 2003, Mar-28, Volume: 303, Issue:1

    Topics: Actins; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Calpain; Caspase 3; Caspases; Cell Adhesion; Cell Culture Techniques; Cell Survival; Chick Embryo; Cytoskeleton; DNA; DNA, Complementary; Dose-Response Relationship, Drug; Etoposide; Fibroblasts; Green Fluorescent Proteins; Immunoblotting; Luminescent Proteins; Microfilament Proteins; Microscopy, Fluorescence; Mutagenesis, Site-Directed; Nucleic Acid Synthesis Inhibitors; Phosphatidylinositol 3-Kinases; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; src Homology Domains; Tensins; Time Factors; Transfection

2003
Cleavage of Bax to p18 Bax accelerates stress-induced apoptosis, and a cathepsin-like protease may rapidly degrade p18 Bax.
    Blood, 2003, Oct-01, Volume: 102, Issue:7

    Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Calpain; Caspase 3; Caspase 9; Caspases; Cathepsins; Cell Membrane; Cytochrome c Group; Ecdysterone; Endopeptidases; Etoposide; Gene Expression; HL-60 Cells; Humans; Interleukin-3; K562 Cells; Kidney; Lung Neoplasms; Mice; Mitochondria; Mutagenesis; Peptide Fragments; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; U937 Cells

2003
Association of mitochondrial calpain activation with increased expression and autolysis of calpain small subunit in an early stage of apoptosis.
    International journal of molecular medicine, 2003, Volume: 12, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Autolysis; Breast Neoplasms; Calpain; Cytochrome c Group; Enzyme Activation; Enzyme Inhibitors; Etoposide; Female; Humans; Imidazoles; Jurkat Cells; Male; Mitochondria; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Prostatic Neoplasms; Protein Subunits; Tamoxifen; Tumor Cells, Cultured

2003
Arsenic trioxide-induced death of neuroblastoma cells involves activation of Bax and does not require p53.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, May-01, Volume: 10, Issue:9

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; bcl-2-Associated X Protein; Blotting, Western; Calpain; Carboplatin; Caspase 3; Caspases; Cell Line, Tumor; Cytochromes c; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Humans; Mutation; Neuroblastoma; Oxides; Proto-Oncogene Proteins c-bcl-2; Time Factors; Tumor Suppressor Protein p53; Vincristine

2004
Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis.
    Nature cell biology, 2006, Volume: 8, Issue:10

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Autophagy-Related Protein 5; Calpain; Caspases; Cytochromes c; Cytosol; Doxorubicin; Drug Resistance, Neoplasm; Enzyme Activation; Enzyme Inhibitors; Etoposide; Granulocyte-Macrophage Colony-Stimulating Factor; HeLa Cells; Humans; Microtubule-Associated Proteins; Mitochondria; Proto-Oncogene Proteins c-bcl-2; RNA, Small Interfering; Staurosporine

2006
Complement component C1q inhibits beta-amyloid- and serum amyloid P-induced neurotoxicity via caspase- and calpain-independent mechanisms.
    Journal of neurochemistry, 2008, Volume: 104, Issue:3

    Topics: Amyloid beta-Peptides; Animals; Antineoplastic Agents, Phytogenic; Brain; Calpain; Caspases; Cell Survival; Cells, Cultured; Complement C1q; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Etoposide; Immunologic Factors; Membrane Potential, Mitochondrial; Neurons; Rats; Rats, Sprague-Dawley; Serum Amyloid P-Component

2008
Induction of apoptosis in Eμ-myc lymphoma cells in vitro and in vivo through calpain inhibition.
    Experimental hematology, 2012, Volume: 40, Issue:7

    Topics: Acrylates; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; B-Lymphocytes; Calcium-Binding Proteins; Calpain; Caspase Inhibitors; Caspases; Cell Line, Tumor; Cysteine Proteinase Inhibitors; Etoposide; Humans; Lymphoma; Mice; Mice, Transgenic

2012