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etoposide and benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone

etoposide has been researched along with benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone in 66 studies

Research

Studies (66)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's25 (37.88)18.2507
2000's37 (56.06)29.6817
2010's4 (6.06)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cohen, GM; Dinsdale, D; Fearnhead, HO1
Inuzuka, M; Nakamura, T; Takauji, R; Ueda, T; Yoshida, A1
Biemann, HP; Blenis, J; Davis, RJ; Juo, P; Konz, RF; Kuo, CJ; Raingeaud, J; Reynolds, SE1
Henkart, PA; Sarin, A; Wu, ML1
Eastman, A; Morana, SJ; Reynolds, JE; Wolf, CM1
Jung, YK; Kim, TW; Kovacs, DM; Pettingell, WH; Tanzi, RE1
Cao, CX; Pommier, Y; Shao, RG1
Lloyd, RE; Marissen, WE1
Bushell, M; McKendrick, L; Morley, SJ1
Cohen, GM; Dinsdale, D; Zhuang, J2
Bushell, M; Clemens, MJ; Morley, SJ1
Cohen, GM; Green, DR; MacFarlane, M; Sun, XM; Wolf, BB; Zhuang, J1
Cohen, GM; Zhuang, J1
Borst, J; de Vries, E; Tepper, AD; van Blitterswijk, WJ1
Amarante-Mendes, GP; Cotter, TG; Finucane, DM; Green, DR; Martin, SJ; Salvesen, GS1
Benson, RS; Dive, C; Watson, AJ1
Engels, IH; Los, M; Rossmann, E; Schulze-Osthoff, K; Wesselborg, S1
Bantel, H; Engels, IH; Schulze-Osthoff, K; Voelter, W; Wesselborg, S1
Chilvers, ER; Choo, C; Donnelly, SC; Dransfield, I; Haslett, C; MacKinnon, AC; Moore, SM; Rintoul, RC; Salter, D; Sethi, T; Strieter, R1
Anderson, SM; Barzen, KA; Deisher, LM; Hunter, S; Quissell, DO; Reyland, ME1
Gallagher, RE; Huang, XJ; Klein, RS; Wiernik, PH1
Fadeel, B; Hassan, Z; Hellström-Lindberg, E; Zhivotovsky, B1
Fukumoto, J; Gabriele, L; Giannakakou, P; Giese, NA; Morse, HC; Ozato, K; Phung, J; Segal, D; Wang, IM1
Droin, N; Eymin, B; Haugg, M; Munsch, B; Solary, E; Sordet, O; Van de Craen, M; Vandenabeele, P1
Qi, L; Sit, KH1
Amoscato, A; Delach, SM; Gastman, BR; Johnson, DE; Rabinowich, H; Wang, GQ; Wieckowski, E1
Dallaporta, B; Daugas, E; Kroemer, G; Loeffler, M; Maisse, C; Pablo, M; Zamzami, N1
Frost, V; Sinclair, AJ1
Chow, SC; Eriksson, JE; Holmstrom, TH; Johnson, VL; Ko, SC1
Gogvadze, V; Orrenius, S; Robertson, JD; Zhivotovsky, B1
Belka, C; Berg, C; Engels, IH; Gregor, M; Jänicke, RU; Lauber, K; Porter, AG; Schulze-Osthoff, K; Schwenzer, R; Stepczynska, A; Stroh, C; Wajant, H; Wesselborg, S1
Feller, JM; Fraser, MJ; Meng, XW; Ziegler, JB1
Andrews, DW; Annis, MG; Kroemer, G; Leber, B; Penn, LZ; Zamzami, N; Zhu, W1
Cain, K; Cohen, GM; Conley, EC; Langlais, C; Thompson, GJ1
Delach, SM; Dou, QP; Fattman, CL; Johnson, DE1
Mahyar-Roemer, M; Roemer, K1
Mashima, T; Tsuruo, T; Udagawa, S1
Kim, JI; Kook, S; Shim, SR; Song, WK1
Casiano, CA; Johnson, N; Molinaro, C; Wu, X1
Eggen, BJ; Kruijer, W; Schuringa, JJ; Vellenga, E; Wierenga, AT1
Ferraro-Peyret, C; Flacher, M; Genestier, L; Quemeneur, L; Revillard, JP1
Chiu, R; Mukherjee, S; Novikov, L; Shields, D1
Chun, JS; Kim, DH; Kim, W; Kook, S; Shim, SR; Song, WK1
Callea, V; Cutrona, G; Ferrarini, M; Ferraris, AM; Mangiola, M; Morabito, F; Oliva, BM; Rapezzi, D; Rossi, E; Spriano, M; Stelitano, C; Zupo, S1
de Bruin, EC; de Wilde, J; den Otter, I; Medema, JP; Meersma, D; Peltenburg, LT; Schipper, EM1
Hoffarth, S; Huber, C; Milosevic, J; Schuler, M1
Ballestrero, A; Boy, D; Brossart, P; Garuti, A; Mela, GS; Nencioni, A; Patrone, F; Rocco, I; Van Parijs, L; Wesselborg, S1
Bhavsar, T; Hahn, PJ; Hatoum, GF; Nevaldine, B; Phung, Q1
Villunger, A1
Attali, G; Fishelson, Z; Gancz, D1
Alvarez-Leite, JI; Amarante-Mendes, GP; Brumatti, G; Bueno-da-Silva, AE; Rabelo, FL; Ramos, MG1
Gineitis, A; Magnusson, KE; Navakauskiene, R; Savickiene, J; Treigyte, G1
Boustany, RM; Persaud-Sawin, DA1
Farber, JL; Karpinich, NO; Russo, MA; Schneider, T; Tafani, M1
Banning, U; Barthel, H; Kluge, R; Körholz, D; Mauz-Körholz, C; Sabri, O1
Bell, CW; Jiang, W; Pisetsky, DS; Reich, CF1
Goldman, A; Pommier, Y; Sordet, O1
Kudo, Y; Okita, N; Tanuma, S1
Choi, YH; Kim, SH; Kwon, TK; Lee, JT; Lee, TJ; Park, JW; Song, KS1
Hajji, N; Hermanson, O; Joseph, B; Nyman, U; Vlachos, P; Wallenborg, K1
Browne, G; Cohen, GM; Inoue, S; Melino, G1
Delmas, E; Gaumer, S; Guillaume, A; Mignotte, B; Renaud, F; Rodríguez-Enfedaque, A; Vayssière, JL1
Algül, H; Conradt, L; Henrich, A; Krämer, OH; Lesina, M; Reichert, M; Saur, D; Schmid, RM; Schneider, G; Wirth, M1
Denomme, GA; Fernandes, BJ; Micieli, JA; Seto, E; Shu, J; Wang, D1
Fransolet, M; Henry, L; Labied, S; Munaut, C; Nisolle, M; Noël, A1

Other Studies

66 other study(ies) available for etoposide and benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone

ArticleYear
An interleukin-1 beta-converting enzyme-like protease is a common mediator of apoptosis in thymocytes.
    FEBS letters, 1995, Nov-20, Volume: 375, Issue:3

    Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase 1; Cells, Cultured; Cysteine Endopeptidases; Dexamethasone; DNA; Etoposide; Flow Cytometry; Kinetics; Male; Poly(ADP-ribose) Polymerases; Protease Inhibitors; Rats; Rats, Inbred F344; Terpenes; Thapsigargin; Thymus Gland

1995
Role of serine and ICE-like proteases in induction of apoptosis by etoposide in human leukemia HL-60 cells.
    Leukemia, 1996, Volume: 10, Issue:5

    Topics: Amino Acid Chloromethyl Ketones; Amino Acid Sequence; Apoptosis; Caspase 1; Cell Nucleus; Cell-Free System; Culture Media, Conditioned; Cysteine Endopeptidases; DNA Damage; DNA, Neoplasm; Etoposide; HL-60 Cells; Humans; Molecular Sequence Data; Neoplasm Proteins; Protease Inhibitors; Serine Endopeptidases; Serine Proteinase Inhibitors; Tosylphenylalanyl Chloromethyl Ketone

1996
Fas activation of the p38 mitogen-activated protein kinase signalling pathway requires ICE/CED-3 family proteases.
    Molecular and cellular biology, 1997, Volume: 17, Issue:1

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caenorhabditis elegans Proteins; Calcium-Calmodulin-Dependent Protein Kinases; Caspase 1; Caspases; Cysteine Endopeptidases; Dactinomycin; Enzyme Activation; Enzyme Inhibitors; Etoposide; fas Receptor; Helminth Proteins; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; MAP Kinase Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Protease Inhibitors; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Protein-Tyrosine Kinases; Pyridines; Serpins; Signal Transduction; Sorbitol; Transcription, Genetic; Viral Proteins

1997
Different interleukin-1 beta converting enzyme (ICE) family protease requirements for the apoptotic death of T lymphocytes triggered by diverse stimuli.
    The Journal of experimental medicine, 1996, Dec-01, Volume: 184, Issue:6

    Topics: Amino Acid Chloromethyl Ketones; Animals; Antibodies; Apoptosis; Caspase 1; CD3 Complex; Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dexamethasone; Etoposide; fas Receptor; Kinetics; Mice; T-Lymphocytes; Time Factors

1996
The temporal relationship between protein phosphatase, ICE/CED-3 proteases, intracellular acidification, and DNA fragmentation in apoptosis.
    Experimental cell research, 1997, Jan-10, Volume: 230, Issue:1

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caspase 1; Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA Fragmentation; Enzyme Inhibitors; Etoposide; Humans; Hydrogen-Ion Concentration; Intracellular Fluid; Models, Biological; Phosphoprotein Phosphatases; Topoisomerase II Inhibitors

1997
Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease.
    Science (New York, N.Y.), 1997, Jul-18, Volume: 277, Issue:5324

    Topics: Alzheimer Disease; Amino Acid Chloromethyl Ketones; Amino Acid Substitution; Animals; Apoptosis; Caspase 3; Caspases; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Enzyme Activation; Etoposide; Membrane Proteins; Mutation; Oligopeptides; Phosphorylation; Presenilin-1; Presenilin-2; Rats; Staurosporine; Tumor Cells, Cultured

1997
Activation of PKCalpha downstream from caspases during apoptosis induced by 7-hydroxystaurosporine or the topoisomerase inhibitors, camptothecin and etoposide, in human myeloid leukemia HL60 cells.
    The Journal of biological chemistry, 1997, Dec-12, Volume: 272, Issue:50

    Topics: Alkaloids; Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Enzyme Activation; Enzyme Inhibitors; Etoposide; HL-60 Cells; Humans; Isoenzymes; Protein Kinase C; Protein Kinase C-alpha; Staurosporine; Up-Regulation

1997
Eukaryotic translation initiation factor 4G is targeted for proteolytic cleavage by caspase 3 during inhibition of translation in apoptotic cells.
    Molecular and cellular biology, 1998, Volume: 18, Issue:12

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caspase 3; Caspases; Cisplatin; Cytochrome c Group; Deoxyadenine Nucleotides; Etoposide; Eukaryotic Initiation Factor-4G; HeLa Cells; Humans; Kinetics; Oligopeptides; Peptide Initiation Factors; Protease Inhibitors; Protein Biosynthesis; Recombinant Proteins

1998
Cleavage of translation initiation factor 4G (eIF4G) during anti-Fas IgM-induced apoptosis does not require signalling through the p38 mitogen-activated protein (MAP) kinase.
    FEBS letters, 1998, Oct-30, Volume: 438, Issue:1-2

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Arsenites; Calcium-Calmodulin-Dependent Protein Kinases; Caspase Inhibitors; Cell Survival; Etoposide; Eukaryotic Initiation Factor-4E; Eukaryotic Initiation Factor-4G; fas Receptor; Humans; Imidazoles; Immunoglobulin M; Jurkat Cells; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Peptide Initiation Factors; Phosphorylation; Poly(A)-Binding Proteins; Protein Biosynthesis; Pyridines; RNA-Binding Proteins; Signal Transduction; Sirolimus

1998
Apoptosis, in human monocytic THP.1 cells, results in the release of cytochrome c from mitochondria prior to their ultracondensation, formation of outer membrane discontinuities and reduction in inner membrane potential.
    Cell death and differentiation, 1998, Volume: 5, Issue:11

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caspase 3; Caspase 7; Caspase Inhibitors; Caspases; Cell Line; Cysteine Proteinase Inhibitors; Cytochrome c Group; Enzyme Activation; Etoposide; Humans; Intracellular Membranes; Lamin Type B; Lamins; Membrane Potentials; Microscopy, Electron; Mitochondria; Nuclear Proteins; Phosphatidylserines; Poly(ADP-ribose) Polymerases; Tosylphenylalanyl Chloromethyl Ketone; Zinc

1998
Degradation of eukaryotic polypeptide chain initiation factor (eIF) 4G in response to induction of apoptosis in human lymphoma cell lines.
    Oncogene, 1998, Dec-03, Volume: 17, Issue:22

    Topics: Amino Acid Chloromethyl Ketones; Antibodies; Apoptosis; Caspase Inhibitors; Caspases; Culture Media, Serum-Free; Cycloheximide; Etoposide; Eukaryotic Initiation Factor-4E; fas Receptor; Half-Life; Humans; Jurkat Cells; Lymphoma; Molecular Weight; Neoplasm Proteins; Oligopeptides; Peptide Initiation Factors; Poly(A)-Binding Proteins; Poly(ADP-ribose) Polymerases; Protein Synthesis Inhibitors; RNA-Binding Proteins; Sirolimus; Tumor Cells, Cultured

1998
Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis.
    The Journal of biological chemistry, 1999, Feb-19, Volume: 274, Issue:8

    Topics: Amino Acid Chloromethyl Ketones; Antibodies; Apoptosis; Caspases; Cysteine Proteinase Inhibitors; Cytochrome c Group; Etoposide; fas Receptor; Humans; Hydrolysis; Jurkat Cells; Protein Processing, Post-Translational; Receptors, Tumor Necrosis Factor

1999
Release of mitochondrial cytochrome c is upstream of caspase activation in chemical-induced apoptosis in human monocytic tumour cells.
    Toxicology letters, 1998, Dec-28, Volume: 102-103

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caspases; Cytochrome c Group; Enzyme Activation; Etoposide; Humans; Membrane Potentials; Mitochondria; Phosphatidylserines; Tosylphenylalanyl Chloromethyl Ketone; Tumor Cells, Cultured

1998
Ordering of ceramide formation, caspase activation, and mitochondrial changes during CD95- and DNA damage-induced apoptosis.
    The Journal of clinical investigation, 1999, Volume: 103, Issue:7

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caspase 8; Caspase 9; Caspases; Ceramides; Cytochrome c Group; DNA Damage; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; Etoposide; fas Receptor; Gamma Rays; Humans; Jurkat Cells; Kinetics; Micronuclei, Chromosome-Defective; Mitochondria; Oligopeptides; Proto-Oncogene Proteins c-bcl-2

1999
Anti-apoptotic oncogenes prevent caspase-dependent and independent commitment for cell death.
    Cell death and differentiation, 1998, Volume: 5, Issue:4

    Topics: Amino Acid Chloromethyl Ketones; Antibodies, Monoclonal; Apoptosis; Caspase Inhibitors; Caspases; Cysteine Proteinase Inhibitors; Dactinomycin; Enzyme Activation; Etoposide; fas Receptor; HL-60 Cells; Humans; Jurkat Cells; Neoplasms; Oncogenes; Staurosporine

1998
Comparative effects of Bcl-2 over-expression and ZVAD.FMK treatment on dexamethasone and VP16-induced apoptosis in CEM cells.
    Cell death and differentiation, 1998, Volume: 5, Issue:5

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caspase Inhibitors; Cell Membrane Permeability; Cell Size; Chromatin; Dexamethasone; Enzyme Inhibitors; Etoposide; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Mitochondria; Proteins; Proto-Oncogene Proteins c-bcl-2; T-Lymphocytes; Tumor Cells, Cultured

1998
Anticancer drugs induce caspase-8/FLICE activation and apoptosis in the absence of CD95 receptor/ligand interaction.
    Blood, 1999, May-01, Volume: 93, Issue:9

    Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; Caspase 8; Caspase 9; Caspases; Cycloheximide; Cysteine Proteinase Inhibitors; Daunorubicin; Doxorubicin; Enzyme Activation; Etoposide; Fas Ligand Protein; fas Receptor; HeLa Cells; Humans; Jurkat Cells; Membrane Glycoproteins; Mitomycin; Recombinant Fusion Proteins; T-Lymphocytes; Transfection; Tumor Cells, Cultured

1999
Mistletoe lectin activates caspase-8/FLICE independently of death receptor signaling and enhances anticancer drug-induced apoptosis.
    Cancer research, 1999, May-01, Volume: 59, Issue:9

    Topics: Amino Acid Chloromethyl Ketones; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptotic Protease-Activating Factor 1; Arabidopsis Proteins; Brefeldin A; Caspase 3; Caspase 8; Caspase 9; Caspases; Cysteine Proteinase Inhibitors; Cytochrome c Group; Drug Synergism; Enzyme Activation; Enzyme Precursors; Etoposide; fas Receptor; Fatty Acid Desaturases; Humans; Jurkat Cells; Leukemia-Lymphoma, Adult T-Cell; Leukemia, B-Cell; Mitochondria; Mitomycin; Neoplasm Proteins; Plant Preparations; Plant Proteins; Proteins; Ribosome Inactivating Proteins, Type 2; Toxins, Biological; Tumor Cells, Cultured

1999
Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: a mechanism for small cell lung cancer growth and drug resistance in vivo.
    Nature medicine, 1999, Volume: 5, Issue:6

    Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; Bradykinin; Carcinoma, Small Cell; Caspase 3; Caspase Inhibitors; Caspases; Cell Adhesion; Cell Division; Collagen; Cyclophosphamide; Doxorubicin; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Extracellular Matrix Proteins; Fibronectins; Galanin; Humans; Integrin beta1; Laminin; Lung Neoplasms; Protein-Tyrosine Kinases; Tenascin; Tumor Cells, Cultured; Tyrphostins

1999
Etoposide-induced activation of c-jun N-terminal kinase (JNK) correlates with drug-induced apoptosis in salivary gland acinar cells.
    Cell death and differentiation, 1999, Volume: 6, Issue:5

    Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cysteine Proteinase Inhibitors; Enzyme Activation; Etoposide; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nucleic Acid Synthesis Inhibitors; p38 Mitogen-Activated Protein Kinases; Parotid Gland; Rats; Saccharomyces cerevisiae Proteins; Salivary Glands; Submandibular Gland

1999
Arsenic trioxide induces apoptosis of myeloid leukemia cells by activation of caspases.
    Medical oncology (Northwood, London, England), 1999, Volume: 16, Issue:1

    Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Caspase Inhibitors; Caspases; Enzyme Activation; Etoposide; Humans; Leukemia, Myeloid; Oxides; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1999
Two pathways of apoptosis induced with all-trans retinoic acid and etoposide in the myeloid cell line P39.
    Experimental hematology, 1999, Volume: 27, Issue:8

    Topics: Actins; Acute Disease; Amino Acid Chloromethyl Ketones; Antibodies, Monoclonal; Apoptosis; Blast Crisis; Caspase Inhibitors; Caspases; Cell Differentiation; Cysteine Proteinase Inhibitors; Cytoskeleton; Erythropoietin; Etoposide; fas Receptor; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Myelodysplastic Syndromes; Neoplasm Proteins; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Tretinoin; Tumor Cells, Cultured

1999
Regulation of apoptosis in myeloid cells by interferon consensus sequence-binding protein.
    The Journal of experimental medicine, 1999, Aug-02, Volume: 190, Issue:3

    Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; bcl-X Protein; Bone Marrow Cells; Caspases; Cells, Cultured; Consensus Sequence; Cysteine Proteinase Inhibitors; Etoposide; Gene Expression Regulation; Hematopoietic Stem Cells; Humans; Interferon Regulatory Factors; Interferons; Lymph Nodes; Mice; Mice, Knockout; Proto-Oncogene Proteins c-bcl-2; Recombinant Proteins; Repressor Proteins; Spleen; U937 Cells

1999
Redistribution of cytochrome c precedes the caspase-dependent formation of ultracondensed mitochondria, with a reduced inner membrane potential, in apoptotic monocytes.
    The American journal of pathology, 1999, Volume: 155, Issue:2

    Topics: Actins; Amino Acid Chloromethyl Ketones; Apoptosis; Caspases; Cycloheximide; Cysteine Proteinase Inhibitors; Cytochrome c Group; Cytoskeleton; Etoposide; Flow Cytometry; Golgi Apparatus; Humans; Immunohistochemistry; Membrane Potentials; Mitochondria; Monocytes; Nucleic Acid Synthesis Inhibitors; Protein Synthesis Inhibitors; Tumor Cells, Cultured

1999
Caspase-induced proteolysis of the cyclin-dependent kinase inhibitor p27Kip1 mediates its anti-apoptotic activity.
    Oncogene, 1999, Aug-26, Volume: 18, Issue:34

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Base Sequence; Calpain; Caspase 3; Caspase 6; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; CDC2-CDC28 Kinases; Cell Cycle Proteins; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cysteine Proteinase Inhibitors; Etoposide; Humans; Leukemia; Leupeptins; Microtubule-Associated Proteins; Molecular Sequence Data; Mutation; Nucleic Acid Synthesis Inhibitors; Oligopeptides; Protein Serine-Threonine Kinases; Thimerosal; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tumor Suppressor Proteins

1999
CpG-specific common commitment in caspase-dependent and -independent cell deaths.
    Molecular cell biology research communications : MCBRC, 2000, Volume: 3, Issue:1

    Topics: Amino Acid Chloromethyl Ketones; Annexin A5; Apoptosis; Caspase Inhibitors; Caspases; Cell Line; CpG Islands; Cysteine Proteinase Inhibitors; DNA Fragmentation; Enzyme Inhibitors; Etoposide; fas Receptor; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Necrosis; Nucleic Acid Synthesis Inhibitors; Oligonucleotides; Phosphatidylserines; Time Factors; Tumor Cells, Cultured

2000
Inhibitor of apoptosis protein hILP undergoes caspase-mediated cleavage during T lymphocyte apoptosis.
    Cancer research, 2000, Apr-01, Volume: 60, Issue:7

    Topics: Amino Acid Chloromethyl Ketones; Antibodies; Apoptosis; Caspases; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Etoposide; fas Receptor; Humans; Jurkat Cells; Proteins; Staurosporine; T-Lymphocytes; X-Linked Inhibitor of Apoptosis Protein

2000
Proteasome activation as a critical event of thymocyte apoptosis.
    Cell death and differentiation, 2000, Volume: 7, Issue:4

    Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Animals; Antioxidants; Apoptosis; Caspase Inhibitors; Caspases; Catalase; Cells, Cultured; Cysteine Endopeptidases; Dactinomycin; Dexamethasone; Enzyme Activation; Etoposide; fas Receptor; Female; Mice; Mice, Inbred BALB C; Mitochondria; Multienzyme Complexes; Proteasome Endopeptidase Complex; T-Lymphocytes

2000
p27KIP1 is down-regulated by two different mechanisms in human lymphoid cells undergoing apoptosis.
    Oncogene, 2000, Jun-22, Volume: 19, Issue:27

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; B-Lymphocytes; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Cell Cycle Proteins; Cell Line, Transformed; Cyclin-Dependent Kinase Inhibitor p27; Cycloheximide; Down-Regulation; Etoposide; fas Receptor; Humans; Jurkat Cells; Microtubule-Associated Proteins; Nucleic Acid Synthesis Inhibitors; Protein Synthesis Inhibitors; Proteins; Signal Transduction; T-Lymphocytes; Tumor Suppressor Proteins

2000
Effector caspases are dispensable for the early nuclear morphological changes during chemical-induced apoptosis.
    Journal of cell science, 2000, Volume: 113 ( Pt 17)

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caspase Inhibitors; Caspases; Cell Line; Cell Nucleus; Chelating Agents; Chromatin; Cysteine Proteinase Inhibitors; Endoplasmic Reticulum; Enzyme Inhibitors; Ethylenediamines; Etoposide; Humans; Jurkat Cells; Mutation; Nuclear Envelope; Nucleic Acid Synthesis Inhibitors; Oligopeptides; Poly(ADP-ribose) Polymerases; Staurosporine

2000
Distinct pathways for stimulation of cytochrome c release by etoposide.
    The Journal of biological chemistry, 2000, Oct-20, Volume: 275, Issue:42

    Topics: Amino Acid Chloromethyl Ketones; Calcium; Cell Membrane Permeability; Cell-Free System; Cysteine Proteinase Inhibitors; Cytochrome c Group; Etoposide; Humans; Jurkat Cells; Kinetics; Mitochondria; Models, Biological; Peptide Hydrolases

2000
Caspase-8/FLICE functions as an executioner caspase in anticancer drug-induced apoptosis.
    Oncogene, 2000, Sep-21, Volume: 19, Issue:40

    Topics: Adenocarcinoma; Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; bcl-X Protein; BH3 Interacting Domain Death Agonist Protein; Breast Neoplasms; Carrier Proteins; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspase 3; Caspase 8; Caspase 9; Caspases; Cysteine Proteinase Inhibitors; Enzyme Activation; Enzyme Precursors; Etoposide; fas Receptor; Humans; Intracellular Signaling Peptides and Proteins; Jurkat Cells; Mitochondria; Mitomycin; Neoplasm Proteins; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured

2000
Caspase-3-dependent and caspase-3-independent pathways leading to chromatin DNA fragmentation in HL-60 cells.
    Apoptosis : an international journal on programmed cell death, 2000, Volume: 5, Issue:1

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Apoptosis Regulatory Proteins; Aurintricarboxylic Acid; Caspase 3; Caspase Inhibitors; Caspases; Cell Nucleus; Chromatin; DNA Fragmentation; Etoposide; HL-60 Cells; Humans; Hydroxychloroquine; Oligopeptides; Proteins; Subcellular Fractions

2000
Endoplasmic reticulum localized Bcl-2 prevents apoptosis when redistribution of cytochrome c is a late event.
    Oncogene, 2001, Apr-12, Volume: 20, Issue:16

    Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; bcl-2-Associated X Protein; Caspases; Ceramides; Cysteine Proteinase Inhibitors; Cytochrome c Group; Endoplasmic Reticulum; Enzyme Activation; Etoposide; Fibroblasts; Genes, myc; Intracellular Membranes; Membrane Potentials; Mitochondria; Protein Conformation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Staurosporine

2001
Elevated extracellular [K+] inhibits death-receptor- and chemical-mediated apoptosis prior to caspase activation and cytochrome c release.
    The Biochemical journal, 2001, Jul-01, Volume: 357, Issue:Pt 1

    Topics: Amino Acid Chloromethyl Ketones; Antibodies; Apoptosis; Caspase Inhibitors; Caspases; Cysteine Proteinase Inhibitors; Cytochrome c Group; Cytosol; Enzyme Activation; Etoposide; Extracellular Space; fas Receptor; Flow Cytometry; Humans; Intracellular Membranes; Jurkat Cells; Kinetics; Membrane Potentials; Mitochondria; Phosphatidylserines; Potassium; Potassium Chloride; Receptors, Tumor Necrosis Factor; Rubidium; T-Lymphocytes; Tumor Cells, Cultured

2001
Sequential two-step cleavage of the retinoblastoma protein by caspase-3/-7 during etoposide-induced apoptosis.
    Oncogene, 2001, May-24, Volume: 20, Issue:23

    Topics: Amino Acid Chloromethyl Ketones; Amino Acid Motifs; Amino Acid Sequence; Apoptosis; Caspase 3; Caspase 7; Caspase Inhibitors; Caspases; Cell Cycle; Cysteine Proteinase Inhibitors; Etoposide; Humans; Molecular Sequence Data; Nucleic Acid Synthesis Inhibitors; Oligopeptides; Peptide Fragments; Recombinant Proteins; Retinoblastoma Protein; Tumor Cells, Cultured

2001
p21 Waf1/Cip1 can protect human colon carcinoma cells against p53-dependent and p53-independent apoptosis induced by natural chemopreventive and therapeutic agents.
    Oncogene, 2001, Jun-07, Volume: 20, Issue:26

    Topics: Adenocarcinoma; Alleles; Amino Acid Chloromethyl Ketones; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Benzothiazoles; Butyrates; Cisplatin; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cysteine Proteinase Inhibitors; Demecolcine; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Fluorouracil; Gene Expression Regulation, Neoplastic; Genes, p53; Humans; Intracellular Membranes; Membrane Potentials; Mitochondria; Neoplasm Proteins; Recombination, Genetic; Resveratrol; Stilbenes; Thiazoles; Toluene; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2001
Involvement of transcriptional repressor ATF3 in acceleration of caspase protease activation during DNA damaging agent-induced apoptosis.
    Journal of cellular physiology, 2001, Volume: 188, Issue:3

    Topics: Activating Transcription Factor 3; Active Transport, Cell Nucleus; Amino Acid Chloromethyl Ketones; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Camptothecin; Caspase Inhibitors; Caspases; Enzyme Activation; Enzyme Inhibitors; Etoposide; Fibrosarcoma; Gene Expression Regulation; HeLa Cells; Humans; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Repressor Proteins; Topoisomerase I Inhibitors; Transcription Factors; Transfection; Tumor Cells, Cultured

2001
Degradation of focal adhesion proteins paxillin and p130cas by caspases or calpains in apoptotic rat-1 and L929 cells.
    Biochemical and biophysical research communications, 2001, Aug-24, Volume: 286, Issue:3

    Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Calpain; Caspase 3; Caspase Inhibitors; Caspases; Cell Line; Crk-Associated Substrate Protein; Cysteine Proteinase Inhibitors; Cytoskeletal Proteins; Etoposide; Fluorescent Antibody Technique; Focal Adhesions; Oligopeptides; Paxillin; Phosphoproteins; Proteins; Rats; Retinoblastoma-Like Protein p130; Tumor Cells, Cultured

2001
Secondary necrosis is a source of proteolytically modified forms of specific intracellular autoantigens: implications for systemic autoimmunity.
    Arthritis and rheumatism, 2001, Volume: 44, Issue:11

    Topics: Amino Acid Chloromethyl Ketones; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Apoptosis; Autoantigens; Caspases; DNA Topoisomerases, Type I; Drug Combinations; Etoposide; HeLa Cells; Humans; Jurkat Cells; Necrosis; Poly(ADP-ribose) Polymerases; Ribonucleoprotein, U1 Small Nuclear; Staurosporine

2001
Downregulation of IL-6-induced STAT3 tyrosine phosphorylation by TGF-beta1 is mediated by caspase-dependent and -independent processes.
    Leukemia, 2002, Volume: 16, Issue:4

    Topics: Amino Acid Chloromethyl Ketones; Annexin A5; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Carrier Proteins; Caspase 3; Caspase Inhibitors; Caspases; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; Down-Regulation; Electrophoretic Mobility Shift Assay; Epithelial Cells; Etoposide; Humans; Interleukin-6; Intracellular Signaling Peptides and Proteins; Janus Kinase 1; Leukemia, Myeloid, Acute; Phosphorylation; Protein Transport; Protein-Tyrosine Kinases; Repressor Proteins; Signal Transduction; Smad3 Protein; STAT3 Transcription Factor; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling Proteins; Trans-Activators; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Cells, Cultured; Tyrosine

2002
Caspase-independent phosphatidylserine exposure during apoptosis of primary T lymphocytes.
    Journal of immunology (Baltimore, Md. : 1950), 2002, Nov-01, Volume: 169, Issue:9

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caspase 3; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Cell Nucleus; Cells, Cultured; DNA Fragmentation; Enzyme Activation; Etoposide; Humans; Interleukin-2; Intracellular Membranes; Jurkat Cells; Kinetics; Membrane Potentials; Mitochondria; Permeability; Phosphatidylserines; Staurosporine; T-Lymphocyte Subsets; Tumor Cells, Cultured

2002
A caspase cleavage fragment of p115 induces fragmentation of the Golgi apparatus and apoptosis.
    The Journal of cell biology, 2002, Nov-25, Volume: 159, Issue:4

    Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Autoantigens; Carrier Proteins; Caspase Inhibitors; Caspases; Cell Line; Cell Size; Enzyme Inhibitors; Etoposide; Fluorescent Dyes; Golgi Apparatus; Golgi Matrix Proteins; Humans; Membrane Proteins; Mutagenesis, Site-Directed; Nucleic Acid Synthesis Inhibitors; Peptide Fragments; Phosphorylation; Rats; Staurosporine; Vesicular Transport Proteins

2002
Caspase-dependent cleavage of tensin induces disruption of actin cytoskeleton during apoptosis.
    Biochemical and biophysical research communications, 2003, Mar-28, Volume: 303, Issue:1

    Topics: Actins; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Calpain; Caspase 3; Caspases; Cell Adhesion; Cell Culture Techniques; Cell Survival; Chick Embryo; Cytoskeleton; DNA; DNA, Complementary; Dose-Response Relationship, Drug; Etoposide; Fibroblasts; Green Fluorescent Proteins; Immunoblotting; Luminescent Proteins; Microfilament Proteins; Microscopy, Fluorescence; Mutagenesis, Site-Directed; Nucleic Acid Synthesis Inhibitors; Phosphatidylinositol 3-Kinases; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; src Homology Domains; Tensins; Time Factors; Transfection

2003
Expression of CD10 by B-chronic lymphocytic leukemia cells undergoing apoptosis in vivo and in vitro.
    Haematologica, 2003, Volume: 88, Issue:8

    Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Amino Acid Chloromethyl Ketones; Antibodies; Antibodies, Monoclonal; Antigens, CD; Apoptosis; B-Lymphocytes; Cell Line, Tumor; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Immunoglobulin A; Immunoglobulin D; Immunoglobulin M; Leukemia, Lymphocytic, Chronic, B-Cell; Membrane Glycoproteins; Neprilysin; Palatine Tonsil; Vidarabine

2003
A serine protease is involved in the initiation of DNA damage-induced apoptosis.
    Cell death and differentiation, 2003, Volume: 10, Issue:10

    Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Blotting, Western; Caspase 2; Caspase 3; Caspase Inhibitors; Caspases; Cell Line; Cell Line, Tumor; Coumarins; Cysteine Proteinase Inhibitors; DNA Damage; Etoposide; Fibroblasts; Flow Cytometry; Humans; Microscopy, Phase-Contrast; Oligopeptides; Peptide Hydrolases; Poly(ADP-ribose) Polymerases; Rats; Serine Endopeptidases; Serine Proteinase Inhibitors; Sulfones; Tumor Necrosis Factor-alpha

2003
The DNA damage-induced decrease of Bcl-2 is secondary to the activation of apoptotic effector caspases.
    Oncogene, 2003, Oct-09, Volume: 22, Issue:44

    Topics: Adenocarcinoma; Adenoviridae; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Apoptotic Protease-Activating Factor 1; Caspase Inhibitors; Caspases; Cell Transplantation; Dactinomycin; DNA Damage; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Enzyme Activation; Enzyme Inhibitors; Etoposide; Fibroblasts; Gene Deletion; Humans; Mice; Mice, SCID; Pancreatic Neoplasms; Proteins; Proto-Oncogene Proteins c-bcl-2; Transplantation, Heterologous; Tumor Cells, Cultured; Ultraviolet Rays

2003
Tumor necrosis factor-related apoptosis-inducing ligand cooperates with anticancer drugs to overcome chemoresistance in antiapoptotic Bcl-2 family members expressing jurkat cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Feb-15, Volume: 10, Issue:4

    Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis Regulatory Proteins; bcl-X Protein; Caspase 3; Caspase 8; Caspases; Dose-Response Relationship, Drug; Doxorubicin; Enzyme Activation; Etoposide; Flow Cytometry; Humans; Immunoblotting; Jurkat Cells; Ligands; Lymphoma; Membrane Glycoproteins; Membrane Potentials; Organoplatinum Compounds; Oxaliplatin; Proto-Oncogene Proteins c-bcl-2; Time Factors; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha

2004
WR-1065, the active form of amifostine, protects HL-60 cells but not peripheral blood mononuclear cells from radiation and etoposide-induced apoptosis.
    International journal of radiation oncology, biology, physics, 2004, Jul-01, Volume: 59, Issue:3

    Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents, Phytogenic; Apoptosis; Caspase Inhibitors; Cell Survival; Enzyme Inhibitors; Etoposide; HL-60 Cells; Humans; Leukocytes, Mononuclear; Mercaptoethylamines; Radiation-Protective Agents

2004
When cells die II: a comprehensive evaluation of apoptosis and programmed cell death.
    Cell death and differentiation, 2004, Volume: 11, Issue:7

    Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspase Inhibitors; Caspases; Cell Line, Transformed; Cell Transformation, Viral; Cells, Cultured; Cysteine Proteinase Inhibitors; Cytochromes c; Embryo, Mammalian; Enzyme Activation; Enzyme Inhibitors; Etoposide; Fibroblasts; Kinetics; Mitochondria; Nucleic Acid Synthesis Inhibitors; Proto-Oncogene Proteins c-bcl-2; Rats; Signal Transduction; Staurosporine; Temperature; Tumor Suppressor Protein p53

2004
Increased sensitivity of early apoptotic cells to complement-mediated lysis.
    European journal of immunology, 2004, Volume: 34, Issue:11

    Topics: Amino Acid Chloromethyl Ketones; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Apoptosis; Bacterial Proteins; Caspase Inhibitors; Caspases; Complement C3; Complement C9; Enzyme Inhibitors; Etoposide; Flow Cytometry; Genes, bcl-2; Humans; Jurkat Cells; Melitten; Staurosporine; Streptolysins; Transfection

2004
Butyrate increases apoptosis induced by different antineoplastic drugs in monocytic leukemia cells.
    Chemotherapy, 2004, Volume: 50, Issue:5

    Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; Blotting, Western; Butyrates; Caspase Inhibitors; Caspases; Cell Line, Tumor; Cytarabine; DNA Replication; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Etoposide; Humans; Leukemia, Monocytic, Acute; Vincristine

2004
Alterations in protein expression in HL-60 cells during etoposide-induced apoptosis modulated by the caspase inhibitor ZVAD.fmk.
    Annals of the New York Academy of Sciences, 2004, Volume: 1030

    Topics: Actins; Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Nucleus; Cysteine Proteinase Inhibitors; Cytosol; Etoposide; HL-60 Cells; Humans; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-bcl-2

2004
Cell death pathways in juvenile Batten disease.
    Apoptosis : an international journal on programmed cell death, 2005, Volume: 10, Issue:5

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Autophagy; Caspase 3; Caspase 6; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Cell Line; Ceramides; Child; Child, Preschool; Enzyme Activation; Etoposide; Golgi Apparatus; Humans; Membrane Glycoproteins; Models, Biological; Molecular Chaperones; Neuronal Ceroid-Lipofuscinoses; Sphingomyelins; Transfection

2005
The course of etoposide-induced apoptosis in Jurkat cells lacking p53 and Bax.
    Journal of cellular physiology, 2006, Volume: 208, Issue:1

    Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; BH3 Interacting Domain Death Agonist Protein; Caspase Inhibitors; Caspases; Cyclosporine; Cytochromes c; DNA Damage; DNA-Binding Proteins; DNA, Neoplasm; Enzyme Activation; Etoposide; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Jurkat Cells; Mitochondria; Mitochondrial Membranes; Mitochondrial Swelling; Nuclear Proteins; Phosphorylation; Proto-Oncogene Proteins c-abl; Proto-Oncogene Proteins c-bcl-2; T-Lymphocytes; Tumor Protein p73; Tumor Suppressor Protein p53; Tumor Suppressor Proteins

2006
Effect of drug-induced cytotoxicity on glucose uptake in Hodgkin's lymphoma cells.
    European journal of haematology, 2006, Volume: 77, Issue:2

    Topics: 4-Chloro-7-nitrobenzofurazan; Amino Acid Chloromethyl Ketones; Antineoplastic Agents, Phytogenic; B-Lymphocytes; Caspases; Cell Death; Cell Line, Tumor; Cysteine Proteinase Inhibitors; Deoxyglucose; Energy Metabolism; Etoposide; False Negative Reactions; Hodgkin Disease; Humans; Neoplasm Proteins

2006
The extracellular release of HMGB1 during apoptotic cell death.
    American journal of physiology. Cell physiology, 2006, Volume: 291, Issue:6

    Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cell Line; Cycloheximide; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Etoposide; HMGB1 Protein; Humans; Hydroxamic Acids; Protein Synthesis Inhibitors; Staurosporine; Tumor Necrosis Factor-alpha

2006
Topoisomerase II and tubulin inhibitors both induce the formation of apoptotic topoisomerase I cleavage complexes.
    Molecular cancer therapeutics, 2006, Volume: 5, Issue:12

    Topics: Amino Acid Chloromethyl Ketones; Amsacrine; Apoptosis; Caspase Inhibitors; Caspases; Cell Line, Tumor; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Doxorubicin; Enzyme Inhibitors; Etoposide; HL-60 Cells; Humans; Paclitaxel; Reactive Oxygen Species; Topoisomerase II Inhibitors; Tubulin Modulators; Vinblastine

2006
Checkpoint kinase 1 is cleaved in a caspase-dependent pathway during genotoxic stress-induced apoptosis.
    Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:2

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caspase Inhibitors; Caspases; Checkpoint Kinase 1; Cisplatin; DNA Fragmentation; Etoposide; HeLa Cells; Humans; Mutagens; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Protein Kinases

2007
Overexpression of Par-4 enhances thapsigargin-induced apoptosis via down-regulation of XIAP and inactivation of Akt in human renal cancer cells.
    Journal of cellular biochemistry, 2008, Feb-01, Volume: 103, Issue:2

    Topics: Adenocarcinoma, Clear Cell; Amino Acid Chloromethyl Ketones; Apoptosis; Apoptosis Regulatory Proteins; Caspases; Cell Division; Cell Line, Tumor; Endoplasmic Reticulum; Enzyme Activation; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Kidney Neoplasms; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Recombinant Fusion Proteins; Thapsigargin; TNF-Related Apoptosis-Inducing Ligand; Transfection; X-Linked Inhibitor of Apoptosis Protein

2008
Combinatorial action of the HDAC inhibitor trichostatin A and etoposide induces caspase-mediated AIF-dependent apoptotic cell death in non-small cell lung carcinoma cells.
    Oncogene, 2008, May-15, Volume: 27, Issue:22

    Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Inducing Factor; bcl-2-Associated X Protein; bcl-X Protein; Carcinoma, Non-Small-Cell Lung; Caspase Inhibitors; Caspases; Drug Evaluation, Preclinical; Etoposide; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Lung Neoplasms; Models, Biological; RNA, Small Interfering; Signal Transduction; Tumor Cells, Cultured

2008
Ordering of caspases in cells undergoing apoptosis by the intrinsic pathway.
    Cell death and differentiation, 2009, Volume: 16, Issue:7

    Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents, Phytogenic; Apoptosis; Caspase Inhibitors; Caspases; Cell Line, Tumor; Cysteine Proteinase Inhibitors; Etoposide; Gene Knockdown Techniques; Humans; Jurkat Cells; Lamin Type A; RNA, Small Interfering

2009
zVAD-fmk upregulates caspase-9 cleavage and activity in etoposide-induced cell death of mouse embryonic fibroblasts.
    Biochimica et biophysica acta, 2012, Volume: 1823, Issue:8

    Topics: Amino Acid Chloromethyl Ketones; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Caspase 3; Caspase 6; Caspase 9; Caspase Inhibitors; Cells, Cultured; Cytochromes c; Drug Synergism; Embryo, Mammalian; Enzyme Activation; Etoposide; Fibroblasts; Membrane Potential, Mitochondrial; Mice; Tumor Suppressor Protein p53; Up-Regulation

2012
Mdm2 inhibitors synergize with topoisomerase II inhibitors to induce p53-independent pancreatic cancer cell death.
    International journal of cancer, 2013, May-15, Volume: 132, Issue:10

    Topics: Amino Acid Chloromethyl Ketones; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Line, Tumor; Deoxycytidine; Disease Models, Animal; DNA Damage; Doxorubicin; Drug Synergism; Etoposide; Gemcitabine; Imidazoles; Immunohistochemistry; Immunoprecipitation; Indoles; Mice; Pancreatic Neoplasms; Piperazines; Proto-Oncogene Proteins c-mdm2; Pyrrolidinones; Topoisomerase II Inhibitors

2013
Antibody-mediated glycophorin C coligation on K562 cells induces phosphatidylserine exposure and cell death in an atypical apoptotic process.
    Transfusion, 2013, Volume: 53, Issue:10

    Topics: Amino Acid Chloromethyl Ketones; Antibodies, Monoclonal; Apoptosis; Cell Proliferation; Erythropoiesis; Etoposide; Glycophorins; Humans; K562 Cells; Phosphatidylserines

2013
In vitro evaluation of the anti-apoptotic drug Z-VAD-FMK on human ovarian granulosa cell lines for further use in ovarian tissue transplantation.
    Journal of assisted reproduction and genetics, 2015, Volume: 32, Issue:10

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Caspase Inhibitors; Cell Hypoxia; Cell Line; Cell Survival; Etoposide; Female; Granulosa Cells; Humans; Ovary; Poly(ADP-ribose) Polymerases; Tumor Suppressor Protein p53

2015