etoposide has been researched along with ascorbic acid in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.33) | 18.7374 |
| 1990's | 5 (16.67) | 18.2507 |
| 2000's | 8 (26.67) | 29.6817 |
| 2010's | 16 (53.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Liu, P; Peng, X; Tao, H; Wang, W; Wang, Y; Zhu, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Kittakoop, P; Mahidol, C; Prachya, S; Ruchirawat, S; Tianpanich, K; Wiyakrutta, S | 1 |
| Calvo, A; Domínguez-Álvarez, E; Font, M; Jacob, C; Palop, JA; Plano, D; Prior, C; Sanmartín, C | 1 |
| González, MA | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Ayati, A; Emami, S; Esmaeili, R; Firoozpour, L; Foroumadi, A; Majidzadeh-A, K; Moghimi, S; Oghabi Bakhshaiesh, T; Safavi, M | 1 |
| de Ruiter, C; de Vries, J; Gobas, F; Kootstra, PR; Pinedo, HM; van Maanen, JM | 1 |
| Gantchev, TG; Kagan, VE; Stoyanovsky, DA; van Lier, JE; Yalowich, JC | 1 |
| Day, BW; Gantchev, TG; Goldman, R; Kagan, VE; Stoyanovsky, DA; Yalowich, JC | 1 |
| Gantchev, T; Kagan, V; Stoyanovsky, D; Yalowich, J | 1 |
| Bello, BD; Comporti, M; Maellaro, E | 1 |
| Borisenko, GG; Fabisiak, JP; Kagan, VE; Thampatty, P; Tyurin, VA; Tyurina, YY; Yalowich, JC | 1 |
| Bergman, GF; Blumberg, JB; Carlson, JL; Furr, CE; Galloway, JR; Griffith, DP; Jonas, CR; Jones, DP; Puckett, AB; Szeszycki, EE; Tyre, C; Ziegler, TR | 1 |
| Khanna, N; Reddy, VG; Singh, N | 1 |
| Blair, IA; Boston, R; Felix, CA; Pang, S; Scavuzzo, J; Zheng, N | 1 |
| Gokhalé, P; Morrison, MJ; Patel, T; Vissers, MC | 1 |
| Cai, Y; Ding, J; Lin, L; Lu, J; Miao, Z | 1 |
| Benvegnú, DM; Bonfanti, G; Frediani, AV; Gonçalves, TL; Rocha, JB | 1 |
| Al-Bader, MM; Khan, KM; Kilarkaje, N; Mousa, AM | 1 |
| Al-Bader, M; Kilarkaje, N | 1 |
| Kilarkaje, N | 1 |
| Ando, K; Kawada, H; Kobayashi, H; Miyamoto, M; Murayama, H; Ogawa, Y; Ohmachi, K; Onizuka, M; Sawanobori, M; Shirasugi, Y; Tazume, K; Toyosaki, M; Tsuboi, K; Tsuma-Kaneko, M; Wasada, I | 1 |
| Aqaqe, N; Biechonski, S; Elad, D; Gourevich, D; Grisaru, D; Jaffa, AJ; Milyavsky, M; Olender, L; Rall, M; Raz, Y; Trakhtenbrot, L; Wiesmuller, L; Yassin, M; Zipin-Roitman, A | 1 |
| Ceylan, S; Gokturk, D; Kelebek, H; Yilmaz, DM | 1 |
2 review(s) available for etoposide and ascorbic acid
| Article | Year |
|---|---|
Synthetic derivatives of aromatic abietane diterpenoids and their biological activities.
Topics: Diterpenes; Molecular Structure | 2014 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
2 trial(s) available for etoposide and ascorbic acid
| Article | Year |
|---|---|
Plasma antioxidant status after high-dose chemotherapy: a randomized trial of parenteral nutrition in bone marrow transplantation patients.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Ascorbic Acid; Bone Marrow Neoplasms; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Etoposide; Female; Glutathione; Glutathione Peroxidase; Humans; Male; Middle Aged; Parenteral Nutrition, Total; Vitamin E; Zinc | 2000 |
Phase I Clinical Trial of Intravenous L-ascorbic Acid Following Salvage Chemotherapy for Relapsed B-cell non-Hodgkin's Lymphoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Cyclophosphamide; Cytarabine; Dexamethasone; Etoposide; Female; Humans; Infusions, Intravenous; Lymphoma, B-Cell; Male; Middle Aged; Rituximab; Salvage Therapy; Treatment Outcome | 2014 |
26 other study(ies) available for etoposide and ascorbic acid
| Article | Year |
|---|---|
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cerebrosides of the halotolerant fungus Alternaria raphani isolated from a sea salt field.
Topics: Alkaloids; Alternaria; Anti-Bacterial Agents; Bacillus subtilis; Candida albicans; Cerebrosides; Crystallography, X-Ray; Escherichia coli; Marine Biology; Microbial Sensitivity Tests; Molecular Structure; Salts; Seawater | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Radical scavenging and antioxidant activities of isocoumarins and a phthalide from the endophytic fungus Colletotrichum sp.
Topics: Antineoplastic Agents; Antioxidants; Aromatase Inhibitors; Benzofurans; Biphenyl Compounds; Colletotrichum; Drug Screening Assays, Antitumor; Free Radical Scavengers; Hep G2 Cells; HL-60 Cells; Humans; Isocoumarins; Lactones; Molecular Structure; Picrates; Piper; Structure-Activity Relationship; Thailand | 2011 |
Synthesis and antiproliferative activity of novel selenoester derivatives.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Design; Esters; Humans; Molecular Structure; Organoselenium Compounds; Oxidation-Reduction | 2014 |
Synthesis and biological evaluation of new coumarins bearing 2,4-diaminothiazole-5-carbonyl moiety.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Coumarins; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Hep G2 Cells; Humans; MCF-7 Cells; Molecular Structure; Structure-Activity Relationship; Thiazoles | 2018 |
The role of metabolic activation by cytochrome P-450 in covalent binding of VP 16-213 to rat liver and HeLa cell microsomal proteins.
Topics: Animals; Ascorbic Acid; Biotransformation; Cytochrome P-450 Enzyme System; Etoposide; HeLa Cells; Humans; In Vitro Techniques; Microsomes; Microsomes, Liver; NADP; Neoplasm Proteins; Nitrogen Oxides; Phenobarbital; Podophyllotoxin; Proadifen; Protein Binding; Pyridines; Rats; Rats, Inbred Strains | 1985 |
Interactions of phenoxyl radical of antitumor drug, etoposide, with reductants in solution and in cell and nuclear homogenates: electron spin resonance and high-performance liquid chromatography.
Topics: Antioxidants; Ascorbic Acid; Azo Compounds; Cell Line; Cell Nucleus; Chromatography, High Pressure Liquid; Electron Spin Resonance Spectroscopy; Etoposide; Free Radicals; Glutathione; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Molecular Structure; Monophenol Monooxygenase; Phenols; Tumor Cells, Cultured | 1994 |
Ascorbate is the primary reductant of the phenoxyl radical of etoposide in the presence of thiols both in cell homogenates and in model systems.
Topics: Animals; Ascorbic Acid; Electron Spin Resonance Spectroscopy; Etoposide; Free Radicals; Liver; Male; Monophenol Monooxygenase; Oxidation-Reduction; Phenols; Rats; Rats, Sprague-Dawley; Retina; Subcellular Fractions; Sulfhydryl Compounds; Thioctic Acid | 1994 |
Tyrosinase-induced phenoxyl radicals of etoposide (VP-16): interaction with reductants in model systems, K562 leukemic cell and nuclear homogenates.
Topics: Ascorbic Acid; Cell Nucleus; Chromatography, High Pressure Liquid; Deferoxamine; Electron Spin Resonance Spectroscopy; Etoposide; Free Radicals; Glutathione; Humans; Leukemia; Monophenol Monooxygenase; Oxidation-Reduction; Phenols; Thioctic Acid; Tumor Cells, Cultured | 1993 |
Protection by ascorbate against apoptosis of thymocytes: implications of ascorbate-induced nonlethal oxidative stress and poly(ADP-ribosyl)ation.
Topics: Animals; Apoptosis; Ascorbic Acid; Dehydroascorbic Acid; DNA; Enzyme Inhibitors; Etoposide; Free Radicals; Hydrogen Peroxide; Male; Methylprednisolone; NAD; Neuroprotective Agents; Oxidative Stress; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Terpenes; Thapsigargin; Thymus Gland | 1996 |
Mechanism-based chemopreventive strategies against etoposide-induced acute myeloid leukemia: free radical/antioxidant approach.
Topics: Acute Disease; Antineoplastic Agents, Phytogenic; Antioxidants; Ascorbic Acid; Chromans; DNA Topoisomerases, Type II; DNA, Neoplasm; Electrons; Etoposide; Free Radicals; HL-60 Cells; Humans; Hydrogen Peroxide; Leukemia, Myeloid; Oxidation-Reduction; Peroxidase; Phospholipids; Sulfhydryl Compounds; Vitamin E | 1999 |
Vitamin C augments chemotherapeutic response of cervical carcinoma HeLa cells by stabilizing P53.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Ascorbic Acid; bcl-2-Associated X Protein; Cell Cycle; Cisplatin; Down-Regulation; Drug Stability; Drug Synergism; Etoposide; Female; HeLa Cells; Humans; Oncogene Proteins, Viral; Papillomaviridae; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Telomerase; Transcription, Genetic; Tumor Suppressor Protein p53; Uterine Cervical Neoplasms | 2001 |
Simultaneous determination of etoposide and its catechol metabolite in the plasma of pediatric patients by liquid chromatography/tandem mass spectrometry.
Topics: Antineoplastic Agents, Phytogenic; Ascorbic Acid; Calibration; Catechols; Child; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Stability; Etoposide; Genotype; Humans; Linear Models; Mass Spectrometry; Mixed Function Oxygenases; Oxidation-Reduction; Quinine; Reproducibility of Results; Sensitivity and Specificity | 2001 |
The effect of intracellular ascorbate on the susceptibility of HL60 and Jurkat cells to chemotherapy agents.
Topics: Antineoplastic Agents; Antioxidants; Apoptosis; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Caspases; Cell Count; Dehydroascorbic Acid; Drug Resistance, Neoplasm; Etoposide; HL-60 Cells; Humans; Jurkat Cells; Melphalan; Oxides | 2006 |
Reactive oxygen species contribute to cell killing and P-glycoprotein downregulation by salvicine in multidrug resistant K562/A02 cells.
Topics: Acetylcysteine; Antineoplastic Agents; Ascorbic Acid; ATP Binding Cassette Transporter, Subfamily B, Member 1; DNA Breaks, Double-Stranded; Drug Resistance, Multiple; Etoposide; Glutathione; Humans; Hydrogen Peroxide; K562 Cells; Naphthoquinones; Reactive Oxygen Species | 2007 |
delta-Aminolevulinate dehydratase activity and oxidative stress during melphalan and cyclophosphamide-BCNU-etoposide (CBV) conditioning regimens in autologous bone marrow transplantation patients.
Topics: Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Biomarkers; Bone Marrow Transplantation; Carmustine; Case-Control Studies; Cyclophosphamide; Etoposide; Humans; Lipid Peroxidation; Male; Melphalan; Middle Aged; Oxidative Stress; Porphobilinogen Synthase; Reactive Oxygen Species; Sulfhydryl Compounds; Transplantation Conditioning; Transplantation, Autologous | 2009 |
Antioxidants enhance the recovery of three cycles of bleomycin, etoposide, and cisplatin-induced testicular dysfunction, pituitary-testicular axis, and fertility in rats.
Topics: alpha-Tocopherol; Animals; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Ascorbic Acid; Atrophy; Bleomycin; Blotting, Western; Cisplatin; Cytoprotection; Disease Models, Animal; Drug Combinations; Enzyme-Linked Immunosorbent Assay; Etoposide; Female; Fertility; Hormones; Immunohistochemistry; Male; Pituitary Gland; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Recovery of Function; Selenium; Sperm Count; Sperm Motility; Spermatogenesis; Testicular Diseases; Testis; Time Factors; Transferrin; Zinc | 2013 |
Effects of antioxidants on drugs used against testicular cancer-induced alterations in metastasis-associated protein 1 signaling in the rat testis.
Topics: Actins; alpha-Tocopherol; Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Ascorbic Acid; Bleomycin; Cisplatin; Disease Models, Animal; DNA Damage; Dose-Response Relationship, Drug; Etoposide; Histone Deacetylases; Male; Proteins; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Selenium; Signal Transduction; Testicular Neoplasms; Testis; Up-Regulation | 2016 |
Effects of combined treatment of α-tocopherol, L-ascorbic acid, selenium and zinc on bleomycin, etoposide and cisplatin-induced alterations in testosterone synthesis pathway in rats.
Topics: alpha-Tocopherol; Animals; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Ascorbic Acid; Bleomycin; Blotting, Western; Cisplatin; Dose-Response Relationship, Drug; Down-Regulation; Drug Therapy, Combination; Etoposide; Male; Rats; Rats, Sprague-Dawley; Selenium; Testosterone; Time Factors; Up-Regulation; Zinc | 2014 |
Quercetin alters the DNA damage response in human hematopoietic stem and progenitor cells via TopoII- and PI3K-dependent mechanisms synergizing in leukemogenic rearrangements.
Topics: Adult; Ascorbic Acid; Cell Culture Techniques; Cell Transformation, Neoplastic; Cells, Cultured; Colony-Forming Units Assay; DNA Damage; DNA Repair; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Etoposide; Female; Genistein; Hematopoietic Stem Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Infant; Leukemia; Maternal-Fetal Exchange; Myeloid-Lymphoid Leukemia Protein; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pregnancy; Quercetin; Signal Transduction; Topoisomerase II Inhibitors | 2017 |
The Effect of Ascorbic Acid over the Etoposide- and Temozolomide-Mediated Cytotoxicity in Glioblastoma Cell Culture: A Molecular Study.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Central Nervous System Neoplasms; Dacarbazine; DNA Damage; Drug Synergism; Etoposide; Glioblastoma; Humans; Temozolomide | 2018 |