Page last updated: 2024-08-23

etoposide and aphidicolin

etoposide has been researched along with aphidicolin in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19904 (11.11)18.7374
1990's19 (52.78)18.2507
2000's12 (33.33)29.6817
2010's1 (2.78)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cai, W; Hao, Y; Hu, P; Ma, D; Pan, H; Xie, X; Yu, AD; Yu, J; Yuan, J; Zhang, L; Zhu, H1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
D'Incalci, M; Erba, E; Lorico, A; Sen, S1
Murray, AW; Shamu, CE1
Constantinou, A; Grdina, D; Huberman, E; Kiguchi, K1
Beardmore, C; D'Arpa, P; Liu, LF1
Kaufmann, SH1
Bohr, V; Hanawalt, P; Mansbridge, J1
Covey, JM; Holm, C; Kerrigan, D; Pommier, Y1
Chow, KC; Ross, WE1
Lönn, S; Lönn, U1
Bjornsti, MA; Evans, DL; Hall, DJ; Logan, TJ; Mercer, WE1
Alexander, IE; Miller, AD; Russell, DW1
Kohn, KW; O'Connor, PM; Pommier, Y; Shimizu, T1
Berger, NA; Chatterjee, S; Cheng, MF1
Azuma, Y; Kizaki, H; Mizuno, Y; Onishi, Y; Sato, Y; Tadakuma, T1
Duguet, M; Jaxel, C; Portemer, C; Taudou, G1
Báez, A; Casiano, CA; Pommier, Y; Tan, EM; Torres, K1
Johnson, N; Ng, TC; Parkin, JM1
Falaschi, A; Ochem, A; Phan, TN; Tuteja, N; Tuteja, R1
Brooker, DL; Ikegami, R; Rivera-Bennetts, AK; Yager, TD1
Armstrong, MJ; Bradt, CI; Galloway, SM; Greenwood, SK; Hill, RB; Hilliard, CA; Johnson, TE1
Armstrong, MJ; Bean, CL; Galloway, SM; Miller, JE; Nichols, WW; Skopek, TR1
Elgie, AW; Sargent, JM; Taylor, CG; Williamson, CJ1
Alm, K; Oredsson, SM1
Roos, DS; Shaw, MK; Tilney, LG1
Furuichi, Y; Goto, M; Heo, SJ; Nishikawa, K; Sakamoto, S; Shimamoto, A1
Biamonti, G; Ferrari, G; Montecucco, A; Prosperi, E; Rossi, R; Scovassi, AI1
Hara, O; Ikegami, S; Iwamatsu, T; Shibata, Y; Yamashita, M1
Cimprich, KA; Costanzo, V; Gautier, J; Gottesman, M; Lupardus, PJ; Shechter, D1
Staub, M1
Bushman, F; Groschel, B1
Choi, VW; McCarty, DM; Samulski, RJ1
Bissler, JJ; Dixon, K; Robison, JG1
Ahlquist, P; Lambert, PF; Lank, SM; Pearce, SM; Pyeon, D1

Other Studies

36 other study(ies) available for etoposide and aphidicolin

ArticleYear
Small molecule regulators of autophagy identified by an image-based high-throughput screen.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Nov-27, Volume: 104, Issue:48

    Topics: Autophagy; Calcium Channel Blockers; Cell Line, Tumor; Drug Evaluation, Preclinical; Fluspirilene; Glioblastoma; Green Fluorescent Proteins; Humans; Intracellular Membranes; Loperamide; Microtubule-Associated Proteins; Mycotoxins; Peptides; Phagosomes; Phosphatidylinositol Phosphates; Pimozide; Protein Kinases; Recombinant Fusion Proteins; Sirolimus; Small Molecule Libraries; TOR Serine-Threonine Kinases; Trifluoperazine; Zinc Fingers

2007
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
Potentiation of etoposide cytotoxicity against a human ovarian cancer cell line by pretreatment with non-toxic concentrations of methotrexate or aphidicolin.
    European journal of cancer (Oxford, England : 1990), 1992, Volume: 28, Issue:1

    Topics: Aphidicolin; Cell Survival; DNA Topoisomerases, Type I; DNA, Neoplasm; Drug Synergism; Etoposide; Female; Humans; Methotrexate; Mitosis; Ovarian Neoplasms; Tumor Cells, Cultured; Tumor Stem Cell Assay

1992
Sister chromatid separation in frog egg extracts requires DNA topoisomerase II activity during anaphase.
    The Journal of cell biology, 1992, Volume: 117, Issue:5

    Topics: Anaphase; Animals; Aphidicolin; Calcium; Cell Extracts; Cell Nucleus; Chromatids; DNA Replication; DNA Topoisomerases, Type II; Etoposide; Male; Maturation-Promoting Factor; Microscopy, Electron; Ovum; Spermatozoa; Spindle Apparatus; Xenopus laevis

1992
The effect of topoisomerase inhibitors on the expression of differentiation markers and cell cycle progression in human K-562 leukemia cells.
    Experimental cell research, 1992, Volume: 203, Issue:1

    Topics: Amsacrine; Aphidicolin; Cell Cycle; Cell Differentiation; Cycloheximide; Deoxyadenosines; Dose-Response Relationship, Drug; Etoposide; G2 Phase; Hemoglobins; Humans; Kinetics; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Melanins; Mitosis; Novobiocin; Teniposide; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1992
Involvement of nucleic acid synthesis in cell killing mechanisms of topoisomerase poisons.
    Cancer research, 1990, Nov-01, Volume: 50, Issue:21

    Topics: Amsacrine; Animals; Antibiotics, Antineoplastic; Aphidicolin; Camptothecin; Cell Survival; Cricetinae; Cricetulus; Cycloheximide; Deoxyadenosines; Dichlororibofuranosylbenzimidazole; Diterpenes; DNA; Etoposide; Mutagens; Nucleic Acids; RNA; Time Factors; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

1990
Antagonism between camptothecin and topoisomerase II-directed chemotherapeutic agents in a human leukemia cell line.
    Cancer research, 1991, Feb-15, Volume: 51, Issue:4

    Topics: Amsacrine; Aphidicolin; Blotting, Western; Camptothecin; Colony-Forming Units Assay; Cycloheximide; Daunorubicin; Deoxyadenosines; Dichlororibofuranosylbenzimidazole; Diterpenes; DNA Polymerase II; DNA Replication; Drug Synergism; Etoposide; Female; Humans; Leukemia, Promyelocytic, Acute; Mutagens; RNA; Topoisomerase II Inhibitors; Topotecan; Tumor Cells, Cultured

1991
[Isolation of drug-resistant mutant cells].
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1991, Volume: 36, Issue:13

    Topics: Alkylating Agents; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Aphidicolin; Camptothecin; Cell Separation; Drug Resistance; Etoposide; Humans; Hydroxamic Acids; Lovastatin; Monensin; Nucleic Acids; Teniposide; Toxins, Biological; Tunicamycin

1991
Comparative effects of growth inhibitors on DNA replication, DNA repair, and protein synthesis in human epidermal keratinocytes.
    Cancer research, 1986, Volume: 46, Issue:6

    Topics: Anthralin; Aphidicolin; Cells, Cultured; Diterpenes; DNA Repair; DNA Replication; Etoposide; Growth Inhibitors; Humans; Keratins; Molecular Weight; Nalidixic Acid; Novobiocin; Protein Biosynthesis; Skin; Skin Diseases; Topoisomerase II Inhibitors

1986
Differential requirement of DNA replication for the cytotoxicity of DNA topoisomerase I and II inhibitors in Chinese hamster DC3F cells.
    Cancer research, 1989, Nov-15, Volume: 49, Issue:22

    Topics: Amsacrine; Animals; Aphidicolin; Camptothecin; Cell Line; Cell Survival; Cricetinae; Cricetulus; Diterpenes; DNA Replication; Etoposide; Hydroxyurea; Kinetics; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

1989
Topoisomerase-specific drug sensitivity in relation to cell cycle progression.
    Molecular and cellular biology, 1987, Volume: 7, Issue:9

    Topics: Animals; Aphidicolin; Cell Cycle; Cell Line; Cell Survival; Cycloheximide; Diterpenes; DNA Damage; DNA Topoisomerases, Type II; Drug Administration Schedule; Etoposide; Interphase; Mice; Mitosis

1987
5,6-Dichloro-1-beta-O-ribofuranosylbenzimidazole induces DNA damage by interfering with DNA topoisomerase II.
    European journal of biochemistry, 1987, May-04, Volume: 164, Issue:3

    Topics: Aphidicolin; Cells, Cultured; Chemical Precipitation; Dichlororibofuranosylbenzimidazole; Diterpenes; DNA; Electrophoresis, Agar Gel; Etoposide; Humans; Novobiocin; Proteins; Ribonucleosides; Teniposide; Topoisomerase II Inhibitors

1987
Expression of a deletion mutant of the E2F1 transcription factor in fibroblasts lengthens S phase and increases sensitivity to S phase-specific toxins.
    Cancer research, 1995, Jul-01, Volume: 55, Issue:13

    Topics: 3T3 Cells; Animals; Aphidicolin; Apoptosis; Bleomycin; Camptothecin; Carrier Proteins; Cell Cycle; Cell Cycle Proteins; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA; DNA Topoisomerases, Type I; DNA-Binding Proteins; E2F Transcription Factors; E2F1 Transcription Factor; Etoposide; Mice; Retinoblastoma-Binding Protein 1; S Phase; Sequence Deletion; Transcription Factor DP1; Transcription Factors; Tumor Suppressor Protein p53

1995
DNA synthesis and topoisomerase inhibitors increase transduction by adeno-associated virus vectors.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Jun-06, Volume: 92, Issue:12

    Topics: Aphidicolin; Cell Division; Cell Line; Dependovirus; DNA; Etoposide; Genetic Vectors; Humans; Hydroxyurea; Topoisomerase I Inhibitors; Transformation, Genetic

1995
Unscheduled activation of cyclin B1/Cdc2 kinase in human promyelocytic leukemia cell line HL60 cells undergoing apoptosis induced by DNA damage.
    Cancer research, 1995, Jan-15, Volume: 55, Issue:2

    Topics: Aphidicolin; Apoptosis; Camptothecin; CDC2 Protein Kinase; Cyclins; DNA Damage; Enzyme Activation; Etoposide; Humans; Leukemia, Promyelocytic, Acute; Mechlorethamine; Phosphorylation; S Phase; Tumor Cells, Cultured

1995
Schedule-dependent cytotoxicity of topotecan alone and in combination chemotherapy regimens.
    Oncology research, 1994, Volume: 6, Issue:6

    Topics: Alkylating Agents; Animals; Antineoplastic Combined Chemotherapy Protocols; Aphidicolin; Camptothecin; Carmustine; Cell Cycle; Cell Death; Cell Line; Cisplatin; Cricetinae; Cricetulus; DNA Damage; DNA Repair; DNA, Neoplasm; Doxorubicin; Drug Synergism; Etoposide; Fibroblasts; Hydroxyurea; Lung; Melphalan; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Topotecan

1994
Topoisomerase inhibitors induce apoptosis in thymocytes.
    Biochimica et biophysica acta, 1993, Jan-17, Volume: 1175, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aphidicolin; Apoptosis; Azides; Camptothecin; Cell Survival; DNA; Etoposide; Isoquinolines; L-Lactate Dehydrogenase; Male; Mice; Mice, Inbred BALB C; Phorbol 12,13-Dibutyrate; Piperazines; Quinazolines; Quinazolinones; Sodium Azide; Thymus Gland; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Zinc

1993
Inhibition of DNA synthesis and DNA fragmentation in stimulated splenocytes by the concerted action of topoisomerase I and II poisons.
    Biochemical pharmacology, 1993, Jan-26, Volume: 45, Issue:2

    Topics: Animals; Aphidicolin; Camptothecin; DNA; DNA Replication; Etoposide; Mice; Mice, Inbred C57BL; Spleen; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

1993
Expression of proliferation-associated nuclear autoantigens, p330d/CENP-F and PCNA, in differentiation and in drug-induced growth inhibition using two-parameter flow cytometry.
    Cell proliferation, 1996, Volume: 29, Issue:4

    Topics: Aphidicolin; Autoantigens; Camptothecin; Cell Cycle; Cell Differentiation; Centromere; Chromosomal Proteins, Non-Histone; DNA Replication; Etoposide; Flow Cytometry; Fluorescent Antibody Technique, Indirect; Growth Inhibitors; HL-60 Cells; Humans; Microfilament Proteins; Proliferating Cell Nuclear Antigen; Tumor Cells, Cultured

1996
Induction of apoptosis within T lymphoblastoid cells by a topoisomerase I inhibitor.
    Biochemical Society transactions, 1997, Volume: 25, Issue:2

    Topics: Aphidicolin; Apoptosis; Camptothecin; DNA Fragmentation; DNA, Neoplasm; Enzyme Inhibitors; Etoposide; Humans; Jurkat Cells; Kinetics; RNA, Neoplasm; T-Lymphocytes; Time Factors; Topoisomerase I Inhibitors

1997
Inhibition of DNA unwinding and ATPase activities of human DNA helicase II by chemotherapeutic agents.
    Biochemical and biophysical research communications, 1997, Jul-30, Volume: 236, Issue:3

    Topics: Adenosine Triphosphatases; Amsacrine; Antineoplastic Agents; Aphidicolin; Camptothecin; Dactinomycin; Daunorubicin; DNA; DNA Helicases; Ellipticines; Enzyme Inhibitors; Ethidium; Etoposide; Genistein; Humans; Isoflavones; Nogalamycin; Novobiocin; Topoisomerase I Inhibitors

1997
Effect of inhibitors of DNA replication on early zebrafish embryos: evidence for coordinate activation of multiple intrinsic cell-cycle checkpoints at the mid-blastula transition.
    Zygote (Cambridge, England), 1997, Volume: 5, Issue:2

    Topics: Animals; Aphidicolin; Blastocyst; Camptothecin; Cell Cycle; DNA Replication; Embryo, Nonmammalian; Etoposide; Gene Deletion; Mutagenesis; Time Factors; Zebrafish

1997
Fewer chromosome aberrations and earlier apoptosis induced by DNA synthesis inhibitors, a topoisomerase II inhibitor or alkylating agents in human cells with normal compared with mutant p53.
    Mutation research, 1998, Jun-05, Volume: 401, Issue:1-2

    Topics: Alkylating Agents; Antineoplastic Agents; Aphidicolin; Apoptosis; B-Lymphocytes; Cell Division; Cell Line; Chromosome Aberrations; Cytarabine; DNA Replication; Etoposide; Humans; Hydroxyurea; Methotrexate; Mutagenesis; Nucleic Acid Synthesis Inhibitors; Radiation, Ionizing; Topoisomerase II Inhibitors; Tumor Suppressor Protein p53

1998
DNA synthesis inhibition as an indirect mechanism of chromosome aberrations: comparison of DNA-reactive and non-DNA-reactive clastogens.
    Mutation research, 1998, May-25, Volume: 400, Issue:1-2

    Topics: Animals; Aphidicolin; Bromodeoxyuridine; Cell Count; Cell Cycle; CHO Cells; Chromosome Aberrations; Cricetinae; DNA; Etoposide; Flow Cytometry; Mutagenicity Tests; Mutagens; Nucleic Acid Synthesis Inhibitors; Topoisomerase I Inhibitors

1998
Aphidicolin markedly increases the in vitro sensitivity to ara-C of blast cells from patients with AML.
    Advances in experimental medicine and biology, 1999, Volume: 457

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Aphidicolin; Blast Crisis; Bone Marrow Cells; Cell Survival; Cytarabine; Drug Screening Assays, Antitumor; Drug Synergism; Etoposide; Humans; Leukemia, Myeloid, Acute; Tumor Cells, Cultured

1999
The organization of replicon clusters is not affected by polyamine depletion.
    Journal of structural biology, 2000, Volume: 131, Issue:1

    Topics: Amanitins; Amidines; Animals; Antibodies, Monoclonal; Aphidicolin; Bromodeoxyuridine; CHO Cells; Cricetinae; DNA Replication; Eflornithine; Etoposide; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluorescent Antibody Technique; Indans; Microscopy, Confocal; Polyamines; Replicon; S Phase

2000
DNA replication and daughter cell budding are not tightly linked in the protozoan parasite Toxoplasma gondii.
    Microbes and infection, 2001, Volume: 3, Issue:5

    Topics: Animals; Aphidicolin; Cell Division; DNA Replication; DNA, Protozoan; Enzyme Inhibitors; Etoposide; Growth Inhibitors; Humans; Mitochondria; Nucleic Acid Synthesis Inhibitors; Organelles; Topoisomerase II Inhibitors; Toxoplasma; Transcription, Genetic; Vacuoles

2001
Werner helicase relocates into nuclear foci in response to DNA damaging agents and co-localizes with RPA and Rad51.
    Genes to cells : devoted to molecular & cellular mechanisms, 2001, Volume: 6, Issue:5

    Topics: 4-Nitroquinoline-1-oxide; Aphidicolin; Bleomycin; Camptothecin; Cell Line; Cell Nucleus; DNA Damage; DNA Helicases; DNA Replication; DNA-Binding Proteins; Dose-Response Relationship, Drug; Etoposide; Humans; Immunoblotting; Immunohistochemistry; In Situ Hybridization, Fluorescence; Mutagens; Proteins; Rad51 Recombinase; Trans-Activators; Werner Syndrome

2001
Etoposide induces the dispersal of DNA ligase I from replication factories.
    Molecular biology of the cell, 2001, Volume: 12, Issue:7

    Topics: Antineoplastic Agents, Phytogenic; Aphidicolin; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; DNA Damage; DNA Ligase ATP; DNA Ligases; DNA Replication; DNA-Binding Proteins; Enzyme Inhibitors; Etoposide; HeLa Cells; Humans; Nucleic Acid Synthesis Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Staurosporine; Topoisomerase II Inhibitors; Tumor Suppressor Proteins; Ultraviolet Rays

2001
Studies on fertilization in the teleost IV. Effects of aphidicolin and camptothecin on chromosome formation in fertilized medaka eggs.
    Development, growth & differentiation, 2002, Volume: 44, Issue:4

    Topics: Animals; Aphidicolin; Camptothecin; Chromosomes; DNA Polymerase I; DNA Topoisomerases; Etoposide; Fertilization; Meiosis; Mitogen-Activated Protein Kinases; Mitosis; Naphthoquinones; Oryzias; Protein Kinases; Topoisomerase Inhibitors; Zygote

2002
An ATR- and Cdc7-dependent DNA damage checkpoint that inhibits initiation of DNA replication.
    Molecular cell, 2003, Volume: 11, Issue:1

    Topics: Animals; Aphidicolin; Ataxia Telangiectasia Mutated Proteins; Caffeine; Cell Cycle Proteins; Chromatin; DNA; DNA Damage; DNA Replication; Enzyme Inhibitors; Etoposide; Exonucleases; Humans; Macromolecular Substances; Male; Nucleic Acid Synthesis Inhibitors; Oocytes; Phosphoproteins; Protein Serine-Threonine Kinases; Signal Transduction; Spermatozoa; Xenopus laevis; Xenopus Proteins

2003
[Special function of deoxycytidine kinase (dCK) in the activation of chemotherapeutic nucleoside analogs and in the inhibition of cell proliferation].
    Magyar onkologia, 2004, Volume: 48, Issue:3

    Topics: Antineoplastic Agents; Aphidicolin; Cell Proliferation; Deoxycytidine Kinase; Etoposide; Gamma Rays; Humans; Lymphocytes; Nucleosides; Nucleotides; Phosphorylation

2004
Cell cycle arrest in G2/M promotes early steps of infection by human immunodeficiency virus.
    Journal of virology, 2005, Volume: 79, Issue:9

    Topics: Aphidicolin; Camptothecin; Cell Cycle; Cell Division; Cell Line; Dose-Response Relationship, Drug; Enzyme Inhibitors; Etoposide; G2 Phase; HIV; HIV Infections; Humans; Nucleic Acid Synthesis Inhibitors; Paclitaxel; Time Factors; Transduction, Genetic; Virus Replication

2005
Effects of adeno-associated virus DNA hairpin structure on recombination.
    Journal of virology, 2005, Volume: 79, Issue:11

    Topics: Aphidicolin; Base Sequence; Camptothecin; Dependovirus; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA, Circular; DNA, Viral; Etoposide; Genes, Reporter; Genetic Vectors; Genome, Viral; HeLa Cells; Humans; Hydroxyurea; Nucleic Acid Conformation; Recombination, Genetic; Terminal Repeat Sequences

2005
Cell cycle-and proteasome-dependent formation of etoposide-induced replication protein A (RPA) or Mre11/Rad50/Nbs1 (MRN) complex repair foci.
    Cell cycle (Georgetown, Tex.), 2007, Oct-01, Volume: 6, Issue:19

    Topics: Aphidicolin; Cell Cycle; Cell Cycle Proteins; DNA Breaks, Double-Stranded; DNA Repair; DNA-Binding Proteins; Etoposide; HeLa Cells; Humans; Leupeptins; Phosphorylation; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Replication Protein A

2007
Establishment of human papillomavirus infection requires cell cycle progression.
    PLoS pathogens, 2009, Volume: 5, Issue:2

    Topics: Antiviral Agents; Aphidicolin; Cell Cycle; Cell Division; Cell Survival; Cells, Cultured; Etoposide; Gene Expression Regulation, Viral; Genome, Viral; Human papillomavirus 16; Humans; Keratinocytes; Orthomyxoviridae; Prophase; Transcription, Genetic; Virion

2009