Page last updated: 2024-08-23

etoposide and acridines

etoposide has been researched along with acridines in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (50.00)18.2507
2000's4 (28.57)29.6817
2010's3 (21.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Infante Lara, L; Laradji, A; Okoro, CO; Osheroff, N; Sledge, A1
Baguley, BC; Finlay, GJ1
Ford, PJ; Germann, UA; Harding, MW; Mason, VS; Shlyakhter, D1
Adjei, AA; Ames, MM; Charron, M; Kaufmann, SH; Miller, J; Reid, JM; Rowinsky, EK; Sebolt-Leopold, J; Svingen, PA1
Ciesielska, E; Denny, WA; Gniazdowski, M; Pastwa, E; Piestrzeniewicz, MK; Szmigiero, L1
Bastow, KF; Vance, JR1
Austin, CA; Baguley, BC; Finlay, GJ; Lock, RB; Meczes, EL; Perenna Rogers, M; Sullivan, DM; Turnbull, RM1
Austin, CA; Baguley, BC; Errington, F; Li, G; Li, L; Li, W; Tilby, MJ; Willmore, E1
Borst, P; de Haas, M; Evers, R; Kool, M; Smith, AJ; van Deemter, L1
Guo, A; Hu, P; Marinaro, W; Sinko, PJ1
Bally, M; Hu, Y; Krishan, A; Mayer, LD; Nie, W; Sridhar, KS1
Ferguson, DM; Flatten, KS; Gálvez-Peralta, M; Hackbarth, JS; Hiasa, H; Kaufmann, SH; Xing, C1
Allhenn, D; Béduneau, A; Lamprecht, A; Neumann, D; Pellequer, Y1
Chiu, HW; Hong, CW; Huang, WJ; Wang, BJ; Wang, YC; Wang, YJ; Wu, YH; Yeh, YL1

Other Studies

14 other study(ies) available for etoposide and acridines

ArticleYear
Novel trifluoromethylated 9-amino-3,4-dihydroacridin-1(2H)-ones act as covalent poisons of human topoisomerase IIα.
    Bioorganic & medicinal chemistry letters, 2017, 02-01, Volume: 27, Issue:3

    Topics: Acridines; Amsacrine; Antigens, Neoplasm; Antineoplastic Agents; DNA; DNA Cleavage; DNA Topoisomerases, Type II; DNA-Binding Proteins; Enzyme Activation; Humans; Intercalating Agents; Topoisomerase II Inhibitors

2017
Potentiation by phenylbisbenzimidazoles of cytotoxicity of anticancer drugs directed against topoisomerase II.
    European journal of cancer (Oxford, England : 1990), 1990, Volume: 26, Issue:5

    Topics: Acridines; Amsacrine; Animals; Antineoplastic Agents; Benzimidazoles; Bisbenzimidazole; Colonic Neoplasms; Doxorubicin; Drug Synergism; Etoposide; Fluorescent Dyes; Leukemia L1210; Lung Neoplasms; Melanoma; Mice; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Tumor Stem Cell Assay

1990
Chemosensitization and drug accumulation effects of VX-710, verapamil, cyclosporin A, MS-209 and GF120918 in multidrug resistant HL60/ADR cells expressing the multidrug resistance-associated protein MRP.
    Anti-cancer drugs, 1997, Volume: 8, Issue:2

    Topics: Acridines; Affinity Labels; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Cyclosporine; Daunorubicin; Doxorubicin; Drug Resistance, Multiple; Etoposide; Fluoresceins; HL-60 Cells; Humans; Isoquinolines; Multidrug Resistance-Associated Proteins; Piperidines; Pyridines; Quinolines; Tetrahydroisoquinolines; Tritium; Verapamil; Vincristine

1997
Effect of pyrazoloacridine (NSC 366140) on DNA topoisomerases I and II.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:3

    Topics: Acridines; Antineoplastic Agents; Cell Survival; Doxorubicin; Etoposide; Humans; Leukemia, Myeloid; Pyrazoles; Saccharomyces cerevisiae; Subcellular Fractions; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1998
Cytotoxic and DNA-damaging properties of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA) and its analogues.
    Biochemical pharmacology, 1998, Aug-01, Volume: 56, Issue:3

    Topics: Acridines; Animals; Antineoplastic Agents; DNA; DNA Damage; Enzyme Inhibitors; Etoposide; Mice; Razoxane; RNA; Topoisomerase II Inhibitors

1998
Inhibition of DNA topoisomerase II catalytic activity by the antiviral agents 7-chloro-1,3-dihydroxyacridone and 1,3,7-trihydroxyacridone.
    Biochemical pharmacology, 1999, Aug-15, Volume: 58, Issue:4

    Topics: Acridines; Amsacrine; Antineoplastic Agents; Antiviral Agents; Catalysis; DNA; Enzyme Inhibitors; Etoposide; Humans; Plasmids; Topoisomerase II Inhibitors

1999
Carbamate analogues of amsacrine active against non-cycling cells: relative activity against topoisomerases IIalpha and beta.
    Cancer chemotherapy and pharmacology, 1999, Volume: 44, Issue:4

    Topics: Acridines; Amsacrine; Animals; Antigens, Neoplasm; Antineoplastic Agents; Carcinoma, Lewis Lung; Cell Cycle; CHO Cells; Cricetinae; DNA Topoisomerases, Type II; DNA-Binding Proteins; Etoposide; Humans; Isoenzymes; Mice; Poly-ADP-Ribose Binding Proteins; Saccharomyces cerevisiae; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1999
Murine transgenic cells lacking DNA topoisomerase IIbeta are resistant to acridines and mitoxantrone: analysis of cytotoxicity and cleavable complex formation.
    Molecular pharmacology, 1999, Volume: 56, Issue:6

    Topics: Acridines; Amsacrine; Animals; Antigens, Neoplasm; Antineoplastic Agents; Cell Survival; Cells, Cultured; DNA Topoisomerases, Type II; DNA-Binding Proteins; Etoposide; Isoenzymes; Mice; Mice, Transgenic; Mitoxantrone; Topoisomerase II Inhibitors

1999
Inhibitory effect of the reversal agents V-104, GF120918 and Pluronic L61 on MDR1 Pgp-, MRP1- and MRP2-mediated transport.
    British journal of cancer, 2000, Volume: 83, Issue:3

    Topics: Acridines; Anion Transport Proteins; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Carrier Proteins; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Fluoresceins; Humans; Isoquinolines; Methamphetamine; Poloxamer; Tetrahydroisoquinolines; Time Factors; Vinblastine

2000
Delineating the contribution of secretory transporters in the efflux of etoposide using Madin-Darby canine kidney (MDCK) cells overexpressing P-glycoprotein (Pgp), multidrug resistance-associated protein (MRP1), and canalicular multispecific organic anion
    Drug metabolism and disposition: the biological fate of chemicals, 2002, Volume: 30, Issue:4

    Topics: Acridines; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Cell Line; Dogs; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Humans; Immunoblotting; Isoquinolines; Kidney; Leukotriene C4; Membrane Transport Proteins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Nucleic Acid Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Tetrahydroisoquinolines

2002
Synergistic cytotoxicity of pyrazoloacridine with doxorubicin, etoposide, and topotecan in drug-resistant tumor cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Feb-01, Volume: 10, Issue:3

    Topics: Acridines; Agar; Antigens, Neoplasm; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Catalysis; Cell Line, Tumor; Cell Nucleus; Clinical Trials as Topic; DNA; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA-Binding Proteins; DNA, Superhelical; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Etoposide; Humans; Inhibitory Concentration 50; Pyrazoles; Topotecan

2004
On the role of topoisomerase I in mediating the cytotoxicity of 9-aminoacridine-based anticancer agents.
    Bioorganic & medicinal chemistry letters, 2009, Aug-01, Volume: 19, Issue:15

    Topics: Acridines; Aminacrine; Antineoplastic Agents; Cell Line; Chemistry, Pharmaceutical; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Doxorubicin; Drug Design; Drug Screening Assays, Antitumor; Etoposide; Humans; Models, Chemical; Neoplasms; RNA, Small Interfering

2009
A "drug cocktail" delivered by microspheres for the local treatment of rat glioblastoma.
    Journal of microencapsulation, 2013, Volume: 30, Issue:7

    Topics: Acridines; Animals; Antineoplastic Agents, Phytogenic; Celecoxib; Cyclooxygenase 2 Inhibitors; Drug Carriers; Etoposide; Glioblastoma; Lactic Acid; Male; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Pyrazoles; Rats; Rats, Inbred F344; Sulfonamides; Tetrahydroisoquinolines

2013
A novel histone deacetylase inhibitor TMU-35435 enhances etoposide cytotoxicity through the proteasomal degradation of DNA-PKcs in triple-negative breast cancer.
    Cancer letters, 2017, 08-01, Volume: 400

    Topics: Acridines; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Carrier Proteins; Cell Line, Tumor; DNA Damage; DNA End-Joining Repair; DNA-Activated Protein Kinase; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Synergism; Etoposide; Female; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Mice; Mice, Inbred BALB C; Mice, Nude; Nuclear Proteins; Proteasome Endopeptidase Complex; Proteolysis; Time Factors; Topoisomerase II Inhibitors; Triple Negative Breast Neoplasms; Ubiquitin-Protein Ligases; Ubiquitination

2017