Compounds > etoposide
Page last updated: 2024-08-23

etoposide and aclarubicin

etoposide has been researched along with aclarubicin in 61 studies

Research

Studies (61)

TimeframeStudies, this research(%)All Research%
pre-199019 (31.15)18.7374
1990's33 (54.10)18.2507
2000's5 (8.20)29.6817
2010's4 (6.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fuse, Y; Katayama, Y; Kitamura, H; Kugai, N; Matsuura, Y; Motoyoshi, K; Nagata, N; Ohkawa, H; Wada, S1
Alberto, P; Mermillod, B; Zulian, GB1
Ashihara, E; Fujita, N; Goto, H; Inaba, T; Ito, K; Murakami, S; Okawa, K; Oku, N; Shimazaki, C; Tsuji, H1
Horiuti, A; Kakishita, E; Kanamaru, A; Masaoka, T; Miyazaki, E; Nagai, K; Shibata, H; Takemoto, Y; Tsubaki, K; Yonezawa, T1
Boesen, AM; Brincker, H; Christensen, BE; Drivsholm, A; Ellegaard, J; Hansen, OP; Hippe, E; Jans, H; Jensen, KB; Pedersen-Bjergaard, J1
Demant, EJ; Hansen, HH; Jensen, PB; Jensen, PS; Sehested, M; Sørensen, BS; Vindeløv, L1
Ausserer, B; Fink, FM; Gadner, H; Grümayer, ER; Kardos, G; Mutz, I; Revesz, T; Schuler, D; Urban, C1
Kanai, M; Kanno, M; Kobayashi, K; Kondo, K; Matano, S; Matsuda, T; Nakamura, S; Ohtake, S; Okafuji, K; Yoshida, T1
Kyo, T; Maehama, S1
Akahoshi, Y; Asou, N; Fujimoto, K; Fukuda, S; Ishimaru, S; Kawano, F; Murai, C; Sawatari, T; Taen, A; Takatsuki, K1
Bennett, JM; Chang, AY; Rowe, JM2
Bernhart, M; Fiedler, E; Kasparu, H; Krieger, O; Lutz, D; Weber, E1
Kano, Y; Masaoka, T; Mikuni, C; Sakamoto, S; Sampi, K; Takagi, T1
Akagi, K; Asou, N; Goto, J; Hamasaki, N; Hidaka, M; Kawano, F; Kurisaki, H; Sawatari, T; Suzushima, H; Takatsuki, K1
Hirai, J; Itoh, K; Kanno, M; Kobayashi, K; Matsuda, T; Naito, K; Nakamura, E; Nakamura, S; Ohtake, S; Yoshida, T1
Fink, FM; Gadner, H; Grümayer, ER; Kardos, G; Revesz, T; Schuler, D2
Berthold, F; Buchmann, S; Dopfer, R; Fengler, R; Graf, N; Holldack, J; Jobke, A; Jürgens, H; Klingebiel, T; Riehm, H1
Hirai, J; Itoh, K; Kanno, M; Kobayashi, K; Matsuda, T; Nakamura, S; Ohtake, S; Saito, Y; Tachimori, K; Yoshida, T1
Beck, JD1
Ehninger, G; Freund, M; Heil, G; Hoelzer, D; Kurrle, E; Link, H; Mitrou, PS1
Lutz, D1
Grönroos, M; Kangas, L; Mäenpää, J1
Ito, K; Kobayashi, K; Matsuda, T; Nakagoshi, T; Nakamura, E; Nakamura, S; Nakanishi, J; Natori, K; Ohtake, S; Yoshida, T1
Gahrton, G1
Hayakawa, O; Kudo, R; Takehara, M1
Aoyagi, A; Arimura, H; Furusawa, S; Koike, T; Noguchi, M; Saito, K; Sakuma, H; Waga, K; Yamada, K; Yamato, H1
Ikeda, T; Nakaike, S; Nakane, S; Ohsawa, M; Suzuki, H; Yamagishi, T1
Engelholm, SA; Jensen, PB; Petersen, LN; Spang-Thomsen, M; Sørensen, BS1
Hansen, HH; Holm, B; Jensen, PB; Sehested, M1
Eisterer, W; Hilbe, W; Ludescher, C; Niederwieser, D; Thaler, J1
Asbury, RF; Cnaan, A; Haller, DG; Harris, J; Johnson, L; Zaentz, SD1
Nakane, S; Suzuki, H1
Perilov, AA; Poddubnaia, IV1
Abe, Y; Hatanaka, T; Ito, T; Kamiya, O; Nagata, K; Ohara, K; Ono, Y; Saito, M1
Dong, J; Johdo, O; Naito, M; Seimiya, H; Tatsuta, T; Tsuruo, T1
Hirakawa, K; Horiike, S; Kaneko, H; Kashima, K; Misawa, S; Nakai, H; Nakao, M; Taniwaki, M; Ueda, Y1
Elonen, E; Jokipii, A; Lautenschlager, I; Lyytikäinen, O; Ruutu, P; Tiittanen, L1
Jensen, PB; Sehested, M1
Anderson, H; Roberge, M1
Boesen, AM; de Nully Brown, P; Grønbaek, K; Hansen, OP; Hippe, E; Hoffmann, T; Jensen, MK; Pedersen-Bjergaard, J; Storm, HH; Thorling, K1
Ezaki, K; Hirano, M; Ino, T; Kojima, H; Maruyama, F; Matsui, T; Miyazaki, H; Nomura, T; Okamoto, M; Tsuzuki, M; Yamaguchi, T1
Hanada, R; Hongo, T; Horikoshi, Y; Sakurai, M; Yajima, S1
Allan, WP; Creighton, AM; Fattman, CL; Hasinoff, BB; Kuschak, TI; Thampatty, P; Yalowich, JC1
Bukh, A; Clausen, N; Hokland, P; Langkjer, ST; Nørgaard, JM; Palshof, T1
Diehl, V; Knöppel-Schwark, S; Lathan, B; Schwonzen, M; Staib, P; Steinmetz, HT; Tesch, H; Voliotis, D; Wickramanayake, PD1
Almqvist, A; Elonen, E; Hänninen, A; Jansson, SE; Järventie, G; Koistinen, P; Koivunen, E; Lahtinen, R; Lehtinen, M; Nousiainen, T; Pelliniemi, TT; Rajamäki, A; Remes, K; Ruutu, T; Timonen, T; Vilpo, J; Volin, L1
Braess, J; Büchner, T; Fuchs, R; Grote-Metke, A; Hiddemann, W; Hossfeld, DK; Kern, W; Kuse, H; Reichle, A; Wörmann, B1
Cao, DC; Higashigawa, M; Hori, H; Inamochi, H; Kawasaki, H; M'soka, T; Nagata, T; Sakurai, M; Shimono, Y; Yan Mao, X1
Bauer, E; Clark, M; Gieseler, F; Nuessler, V; Valsamas, S1
Asbury, R; Dutcher, JP; Haller, DG; Novik, Y; Ryan, LM; Schutt, A1
Barret, JM; Etiévant, C; Guminski, Y; Hill, BT; Kruczynski, A; Perrin, D; van Hille, B1
Hokland, P; Langkjer, ST; Nørgaard, JM; Palshof, T; Pedersen, B1
Eguchi, M; Hayashi, Y; Hibi, S; Hongo, T; Imaizumi, M; Ishii, E; Isoyama, K; Kamada, N; Kawasaki, H; Kinukawa, N; Kosaka, Y; Mizutani, S; Nishimura, S; Oda, M; Oda, T; Okamura, T; Okawa, H; Tsukimoto, I1
Bendix, K; Hokland, P; Kjeldsen, E; Kristensen, JS; Meyer, K; Nørgaard, JM; Olesen, G; Olesen, LH; Pedersen, B1
Feng, Z; Kachnic, LA; Powell, SN; Tokadjian, C; Treszezamsky, AD; Zhang, J1
Chen, X; Gao, L; Kong, P; Li, Y; Liu, Y; Su, Y; Wang, C; Wang, Q; Wang, S; Wen, Q; Yuan, Z; Zeng, Y; Zhang, C; Zhang, X; Zhang, Y1
Groothuis, T; Huijgens, P; Janssen, J; Janssen, L; Kerkhoven, R; Neefjes, J; Nieuwland, M; Ovaa, H; Pang, B; Qiao, X; Rottenberg, S; van Tellingen, O; Velds, A; Zwart, W1
de Jong, J; Neefjes, J; Pang, B; Qiao, X; Wessels, LF1
Huang, Y; Liu, DD; Lv, TT; Xu, J; Yuan, GL; Zhou, XF1

Reviews

1 review(s) available for etoposide and aclarubicin

ArticleYear
Treatment of acute leukemia--advances in chemotherapy, immunotherapy, and bone marrow transplantation.
    Advances in cancer research, 1983, Volume: 40

    Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Age Factors; Aminoacridines; Amsacrine; Anthraquinones; Antibodies, Monoclonal; Azacitidine; Bone Marrow Transplantation; Child; Child, Preschool; Drug Administration Schedule; Etoposide; Humans; Ifosfamide; Immunotherapy; Infant; Interferons; Leukemia; Leukemia, Lymphoid; Liposomes; Middle Aged; Mitoxantrone; Naphthacenes; Prognosis; Teniposide; Transplantation, Homologous; Transplantation, Isogeneic; Vinblastine; Vindesine

1983

Trials

18 trial(s) available for etoposide and aclarubicin

ArticleYear
[Co-operative on salvage chemotherapy with VP-16 for malignant lymphoma. Hanshin Study Group on Treatment for Hematological Disorders].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:4

    Topics: Aclarubicin; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Hodgkin Disease; Humans; Immunoblastic Lymphadenopathy; Leukemia-Lymphoma, Adult T-Cell; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Prednisolone

1992
Aclarubicin plus cytosine arabinoside versus daunorubicin plus cytosine arabinoside in previously untreated patients with acute myeloid leukemia: a Danish national phase III trial. The Danish Society of Hematology Study Group on AML, Denmark.
    Leukemia, 1991, Volume: 5, Issue:6

    Topics: Aclarubicin; Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Chi-Square Distribution; Cytarabine; Daunorubicin; Denmark; Drug Administration Schedule; Etoposide; Humans; Leukemia, Myeloid, Acute; Middle Aged; Regression Analysis; Remission Induction; Survival Rate

1991
Treatment of childhood acute nonlymphocytic leukemia: cooperative Austrian-Hungarian study AML-IGCI-84.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Aclarubicin; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Austria; Child; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Female; Humans; Hungary; Infant; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Life Tables; Male; Multicenter Studies as Topic; Prednisone; Prospective Studies; Remission Induction; Thioguanine; Vincristine

1990
[Aclarubicin-combined combination chemotherapy in patients with refractory or relapsed non-Hodgkin's lymphoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:1

    Topics: Aclarubicin; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carbazilquinone; Drug Resistance; Etoposide; Female; Humans; Ifosfamide; Lymphoma, Non-Hodgkin; Male; Middle Aged; Multicenter Studies as Topic; Prednisolone; Recurrence; Remission Induction; T-Lymphocytes; Vinblastine; Vindesine

1989
[A comparative study of ABEP and ACOPE in the treatment of non-Hodgkin's lymphoma CS IV].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1988, Volume: 29, Issue:9

    Topics: Aclarubicin; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Drug Evaluation; Etoposide; Female; Humans; Lymphoma, Non-Hodgkin; Male; Middle Aged; Neoplasm Staging; Prednisolone; Prospective Studies; Random Allocation; Remission Induction; Vincristine

1988
Aclacinomycin-A in the induction treatment of childhood acute myelogenous leukemia.
    Haematology and blood transfusion, 1987, Volume: 30

    Topics: Aclarubicin; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Clinical Trials as Topic; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Naphthacenes; Prospective Studies; Remission Induction

1987
Aggressive combination chemotherapy of bone marrow relapse in childhood acute lymphoblastic leukemia containing aclacinomycin-A: a multicentric trial.
    Haematology and blood transfusion, 1987, Volume: 30

    Topics: Aclarubicin; Adolescent; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Clinical Trials as Topic; Cytarabine; Etoposide; Female; Germany, West; Humans; Leukemia, Lymphoid; Male; Naphthacenes; Prednisone; Remission Induction

1987
[Comparison of low-dose cytosine arabinoside and aclarubicin in combination with granulocyte colony-stimulating factor to intermediate-dose cytosine arabinoside and mitoxantrone with or without etoposide in the treatment of relapsed acute myeloid leukemia
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1995, Volume: 36, Issue:3

    Topics: Aclarubicin; Adolescent; Adult; Aged; Cytarabine; Drug Administration Schedule; Drug Therapy, Combination; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Recurrence

1995
Treatment of relapsed and refractory acute myelogenous leukaemia with aclacinomycin A (ACA) and etoposide (VP-16).
    Leukemia research, 1994, Volume: 18, Issue:9

    Topics: Aclarubicin; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Retrospective Studies

1994
An Eastern Cooperative Oncology Group phase II study of single agent DHAD, VP-16, aclacinomycin, or spirogermanium in metastatic pancreatic cancer.
    American journal of clinical oncology, 1994, Volume: 17, Issue:2

    Topics: Aclarubicin; Adenocarcinoma; Adjuvants, Immunologic; Antineoplastic Agents; Etoposide; Female; Humans; Male; Mitoxantrone; Organometallic Compounds; Pancreatic Neoplasms; Spiro Compounds; Survival Rate

1994
Long-term survival and development of secondary malignancies in patients with acute myeloid leukemia treated with aclarubicin or daunorubicin plus cytosine arabinoside followed by intensive consolidation chemotherapy in a Danish national phase III trial.
    Leukemia, 1997, Volume: 11, Issue:1

    Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Age Factors; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Follow-Up Studies; Humans; Leukemia, Myeloid; Male; Middle Aged; Neoplasms, Second Primary; Recurrence; Remission Induction; Survival Rate; Survivors

1997
[Short-term intensive treatment for acute myelogenous leukemia (excluding M3 subtype) in adults].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1997, Volume: 38, Issue:3

    Topics: Aclarubicin; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Middle Aged; Mitoxantrone; Time Factors; Vinblastine; Vincristine

1997
Cytosine arabinoside, etoposide and aclarubicin (AVA) for the treatment of acute myeloid leukemia (AML) in elderly patients.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1998, Volume: 9, Issue:2

    Topics: Aclarubicin; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Male

1998
Comparison between four and eight cycles of intensive chemotherapy in adult acute myeloid leukemia: a randomized trial of the Finnish Leukemia Group.
    Leukemia, 1998, Volume: 12, Issue:7

    Topics: Aclarubicin; Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Administration Schedule; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisolone; Prospective Studies; Remission Induction; Vincristine

1998
Combination of aclarubicin and etoposide for the treatment of advanced acute myeloid leukemia: results of a prospective multicenter phase II trial. German AML Cooperative Group.
    Leukemia, 1998, Volume: 12, Issue:10

    Topics: Aclarubicin; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Neutropenia; Prospective Studies; Recurrence; Stomatitis; Survival Rate

1998
Phase II protocol for the evaluation of new treatments in patients with advanced gastric carcinoma: results of ECOG 5282.
    Medical oncology (Northwood, London, England), 1999, Volume: 16, Issue:4

    Topics: Aclarubicin; Adenocarcinoma; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Etoposide; Female; Humans; Male; Mitoxantrone; Organometallic Compounds; Spiro Compounds; Stomach Neoplasms

1999
Superior outcome of infant acute myeloid leukemia with intensive chemotherapy: results of the Japan Infant Leukemia Study Group.
    Blood, 2001, Dec-15, Volume: 98, Issue:13

    Topics: Aclarubicin; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 11; Cytarabine; Disease-Free Survival; DNA-Binding Proteins; Doxorubicin; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Histone-Lysine N-Methyltransferase; Humans; Immunophenotyping; Infant; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Myeloid-Lymphoid Leukemia Protein; Prognosis; Proto-Oncogenes; Remission Induction; Survival Rate; Transcription Factors; Translocation, Genetic; Treatment Outcome; Vincristine

2001
Etoposide in combination with low-dose CAG (cytarabine, aclarubicin, G-CSF) for the treatment of relapsed or refractory acute myeloid leukemia: a multicenter, randomized control trial in southwest China.
    Leukemia research, 2013, Volume: 37, Issue:6

    Topics: Aclarubicin; Adolescent; Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; China; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Treatment Failure; Treatment Outcome; Young Adult

2013

Other Studies

42 other study(ies) available for etoposide and aclarubicin

ArticleYear
Parathyroid hormone-related protein as a cause of hypercalcemia in a B-cell type malignant lymphoma.
    Internal medicine (Tokyo, Japan), 1992, Volume: 31, Issue:8

    Topics: Aclarubicin; Adult; Alkaline Phosphatase; Antineoplastic Combined Chemotherapy Protocols; Calcitriol; Cisplatin; Creatinine; Cyclic AMP; Cytarabine; Etoposide; Glomerular Filtration Rate; Humans; Hydroxycholecalciferols; Hydroxyproline; Hypercalcemia; Ifosfamide; L-Lactate Dehydrogenase; Lymphoma, B-Cell; Male; Osteocalcin; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Prednisolone; Procarbazine; Proteins

1992
ABEP as primary chemotherapy for Hodgkin's disease.
    European journal of cancer (Oxford, England : 1990), 1992, Volume: 28A, Issue:10

    Topics: Aclarubicin; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cytarabine; Doxorubicin; Etoposide; Female; Follow-Up Studies; Hodgkin Disease; Humans; Leukemia, Myeloid, Acute; Male; Mechlorethamine; Middle Aged; Myelodysplastic Syndromes; Neoplasms, Second Primary; Prednisolone; Prednisone; Procarbazine; Vincristine

1992
Collection of peripheral blood stem cells mobilized by high-dose Ara-C plus VP-16 or aclarubicin followed by recombinant human granulocyte-colony stimulating factor.
    Bone marrow transplantation, 1992, Volume: 10, Issue:4

    Topics: Aclarubicin; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Cells; Blood Component Removal; Blood Transfusion, Autologous; Cytarabine; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Hematopoiesis; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Leukemia; Lymphoma; Male; Middle Aged; Recombinant Proteins

1992
Antagonistic effect of aclarubicin on the cytotoxicity of etoposide and 4'-(9-acridinylamino)methanesulfon-m-anisidide in human small cell lung cancer cell lines and on topoisomerase II-mediated DNA cleavage.
    Cancer research, 1990, Jun-01, Volume: 50, Issue:11

    Topics: Aclarubicin; Amsacrine; Carcinoma, Small Cell; Cell Survival; DNA Damage; DNA, Neoplasm; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1990
Salvage chemotherapy of refractory non-Hodgkin's lymphoma with aclacinomycin, behenoyl ara-C, etoposide, and prednisolone.
    Cancer chemotherapy and pharmacology, 1989, Volume: 25, Issue:2

    Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation; Etoposide; Humans; Lymphoma, Non-Hodgkin; Neoplasm Recurrence, Local; Prednisolone; Remission Induction; Time Factors

1989
[Chemotherapy of adult ANLL].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1989, Volume: 30, Issue:8

    Topics: Aclarubicin; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Daunorubicin; Drug Evaluation; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Mitoxantrone; Prednisolone; Remission Induction; Survival Rate; Vincristine

1989
[Relapse of gingival tumor during hematological remission in acute promyelocytic leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1989, Volume: 30, Issue:11

    Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Gingival Neoplasms; Humans; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Middle Aged; Prednisolone; Recurrence; Remission Induction; Vinblastine; Vincristine

1989
Treatment of refractory acute leukaemia with aclacinomycin A.
    Bone marrow transplantation, 1989, Volume: 4 Suppl 3

    Topics: Aclarubicin; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Evaluation; Etoposide; Humans; Leukemia, Myeloid, Acute; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma

1989
Preliminary results of an induction combination regimen including fractionated anthracycline.
    Bone marrow transplantation, 1989, Volume: 4 Suppl 3

    Topics: Aclarubicin; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1989
["AB-Triple V" therapy of relapsed or refractory acute myelogenous leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1989, Volume: 30, Issue:2

    Topics: Aclarubicin; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Remission Induction; Vinblastine; Vincristine; Vindesine

1989
Aclacinomycin A and etoposide (VP-16-213): an effective regimen in previously treated patients with refractory acute myelogenous leukemia.
    Blood, 1988, Volume: 71, Issue:4

    Topics: Aclarubicin; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Naphthacenes; Neoplasm Recurrence, Local; Remission Induction

1988
[Clinical study on advanced non-Hodgkin's lymphoma with special reference to the results of chemotherapies with ACOP, ACOP-E and AclBEP regimen].
    Nihon Gan Chiryo Gakkai shi, 1987, Jul-20, Volume: 22, Issue:6

    Topics: Aclarubicin; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Lymphoma, Non-Hodgkin; Male; Middle Aged; Naphthacenes; Prednisolone; Sex Factors; Vincristine

1987
[Full remission of acute non-lymphatic leukemia lasting for 16 months following combination therapy with aclacinomycin A].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1986, Volume: 134, Issue:8

    Topics: Aclarubicin; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Drug Administration Schedule; Etoposide; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Naphthacenes; Thioguanine

1986
Age adapted induction and intensified consolidation therapy in acute myelogenous leukemia.
    Onkologie, 1986, Volume: 9, Issue:3

    Topics: Aclarubicin; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Naphthacenes; Prognosis

1986
Aclacinomycin-A in the induction treatment of childhood AML.
    Onkologie, 1986, Volume: 9, Issue:3

    Topics: Aclarubicin; Adolescent; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Etoposide; Female; Follow-Up Studies; Humans; Infant; Infusions, Parenteral; Leukemia, Myeloid, Acute; Male; Naphthacenes; Thioguanine

1986
[Various induction therapies in older patients with acute myeloid leukemias].
    Wiener klinische Wochenschrift, 1985, Feb-01, Volume: 97, Issue:3

    Topics: Aclarubicin; Adolescent; Adult; Aged; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Danazol; Dose-Response Relationship, Drug; Etoposide; Female; Humans; Leukapheresis; Leukemia, Myeloid, Acute; Male; Middle Aged; Naphthacenes; Tamoxifen

1985
Response of ovarian cancer to combined cytotoxic agents in the subrenal capsule assay: Part I.
    Obstetrics and gynecology, 1985, Volume: 66, Issue:5

    Topics: Aclarubicin; Adolescent; Adult; Aged; Altretamine; Animals; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cisplatin; Cyclophosphamide; Cystadenocarcinoma; Doxorubicin; Epirubicin; Etoposide; Female; Humans; Methotrexate; Mice; Middle Aged; Mitomycins; Naphthacenes; Neoplasm Transplantation; Ovarian Neoplasms; Tegafur; Tumor Stem Cell Assay; Vincristine

1985
[ABEP chemotherapy in the treatment of advanced non-Hodgkin's lymphomas].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:4 Pt 1

    Topics: Aclarubicin; Adult; Aged; Alopecia; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Leukopenia; Lymphoma; Male; Middle Aged; Naphthacenes; Prednisolone; Thrombocytopenia; Vincristine

1986
[Experimental and clinical study on chemotherapy for cervical adenocarcinoma].
    Nihon Sanka Fujinka Gakkai zasshi, 1995, Volume: 47, Issue:4

    Topics: Aclarubicin; Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Dactinomycin; Drug Administration Schedule; Etoposide; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Mitomycin; Neoplasm Transplantation; Uterine Cervical Neoplasms

1995
Efficient induction of chromosome-type aberrations by topoisomerase II inhibitors closely associated with stabilization of the cleavable complex in cultured fibroblastic cells.
    Mutation research, 1995, Volume: 328, Issue:2

    Topics: 2,4-Dinitrophenol; Aclarubicin; Adenosine Triphosphate; Animals; Camptothecin; Cells, Cultured; Chromosome Aberrations; Cricetinae; Dinitrophenols; DNA; DNA Damage; DNA Topoisomerases, Type II; Doxorubicin; Etoposide; Fibroblasts; Topoisomerase II Inhibitors

1995
Postincubation with aclarubicin reverses topoisomerase II mediated DNA cleavage, strand breaks, and cytotoxicity induced by VP-16.
    Investigational new drugs, 1994, Volume: 12, Issue:4

    Topics: Aclarubicin; Animals; Carcinoma, Small Cell; DNA Damage; DNA, Neoplasm; Etoposide; Humans; Lung Neoplasms; Mice; Time Factors; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Tumor Stem Cell Assay

1994
In vivo inhibition of etoposide-mediated apoptosis, toxicity, and antitumor effect by the topoisomerase II-uncoupling anthracycline aclarubicin.
    Cancer chemotherapy and pharmacology, 1994, Volume: 34, Issue:6

    Topics: Aclarubicin; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Ehrlich Tumor; DNA Topoisomerases, Type II; Etoposide; Female; Male; Mice; Mice, Inbred DBA; Tumor Stem Cell Assay

1994
Differential induction of chromosomal aberrations by topoisomerase inhibitors in cultured Chinese hamster cells.
    Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:2

    Topics: Aclarubicin; Animals; Camptothecin; Cells, Cultured; Chromosome Aberrations; Cricetinae; Cricetulus; Doxorubicin; Etoposide; Fibroblasts; Lung; Mitoxantrone; Sister Chromatid Exchange; Topoisomerase I Inhibitors

1994
[The current chemotherapy of acute myeloid leukemias in adults].
    Terapevticheskii arkhiv, 1993, Volume: 65, Issue:7

    Topics: Aclarubicin; Acute Disease; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Humans; Idarubicin; Leukemia, Myeloid; Mitoxantrone; Prognosis; Remission Induction; Time Factors

1993
[Short-term intensive consolidation chemotherapy in the treatment of acute nonlymphocytic leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:2

    Topics: Aclarubicin; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Prognosis; Survival Rate; Vinblastine; Vincristine

1994
Difference between the resistance mechanisms of aclacinomycin- and adriamycin-resistant P388 cell lines.
    Oncology research, 1995, Volume: 7, Issue:5

    Topics: Aclarubicin; Animals; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Nucleus; DNA Topoisomerases, Type II; DNA, Neoplasm; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Humans; Immunoblotting; Leukemia P388; Tumor Cells, Cultured; Verapamil; Vincristine

1995
Double mutations of the N-ras gene in a patient with acute myelomonocytic leukemia.
    International journal of hematology, 1995, Volume: 61, Issue:4

    Topics: Aclarubicin; Alleles; Antineoplastic Combined Chemotherapy Protocols; Chromosome Deletion; Chromosomes, Human, Pair 12; Chromosomes, Human, Pair 9; Codon; Cytarabine; Daunorubicin; Disease Progression; Doxorubicin; Etoposide; Fatal Outcome; Genes, ras; Genetic Vectors; Humans; Karyotyping; Leukemia, Myelomonocytic, Acute; Male; Mercaptopurine; Middle Aged; Mitoxantrone; Point Mutation; Prednisolone; Vinblastine; Vincristine

1995
Pneumocystis carinii pneumonia in adults with acute leukaemia: is there a need for primary chemoprophylaxis?
    European journal of haematology, 1996, Volume: 56, Issue:3

    Topics: Aclarubicin; Acute Disease; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cohort Studies; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Etoposide; Female; Finland; Humans; Immunocompromised Host; Incidence; Leukemia; Male; Mercaptopurine; Methotrexate; Middle Aged; Mitoxantrone; Pneumonia, Pneumocystis; Prednisone; Premedication; Retrospective Studies; Thioguanine; Trimethoprim, Sulfamethoxazole Drug Combination; Vincristine

1996
Mapping of DNA topoisomerase II poisons (etoposide, clerocidin) and catalytic inhibitors (aclarubicin, ICRF-187) to four distinct steps in the topoisomerase II catalytic cycle.
    Biochemical pharmacology, 1996, Apr-12, Volume: 51, Issue:7

    Topics: Aclarubicin; Blotting, Western; Diterpenes; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Etoposide; Humans; Lung Neoplasms; Razoxane; Tumor Cells, Cultured

1996
Topoisomerase II inhibitors affect entry into mitosis and chromosome condensation in BHK cells.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1996, Volume: 7, Issue:1

    Topics: Aclarubicin; Alkenes; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Cycle Proteins; Cell Line; Chromosomes; Cricetinae; DNA-Binding Proteins; Enzyme Inhibitors; Etoposide; G2 Phase; Guanine Nucleotide Exchange Factors; Kidney; Mitosis; Nuclear Proteins; Okadaic Acid; Phosphoprotein Phosphatases; Polyenes; Pyrones; Razoxane; Temperature; Thiobarbiturates; Topoisomerase II Inhibitors

1996
In vitro drug sensitivity testing can predict induction failure and early relapse of childhood acute lymphoblastic leukemia.
    Blood, 1997, Apr-15, Volume: 89, Issue:8

    Topics: Aclarubicin; Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bleomycin; Bone Marrow; Cell Survival; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Etoposide; Follow-Up Studies; Humans; Infant; Infant, Newborn; Life Tables; Melphalan; Methotrexate; Mitomycin; Mitoxantrone; Neoplastic Stem Cells; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Recurrence; Remission Induction; Tumor Cells, Cultured; Vincristine

1997
Characterization of a Chinese hamster ovary cell line with acquired resistance to the bisdioxopiperazine dexrazoxane (ICRF-187) catalytic inhibitor of topoisomerase II.
    Biochemical pharmacology, 1997, Jun-15, Volume: 53, Issue:12

    Topics: Aclarubicin; Animals; CHO Cells; Cricetinae; DNA Topoisomerases, Type II; Drug Resistance; Ethylenediamines; Etoposide; Glycine; Mutation; Razoxane; Thiobarbiturates; Topoisomerase II Inhibitors; Verapamil

1997
MDR1 gene expression and drug resistance of AML cells.
    British journal of haematology, 1998, Volume: 100, Issue:3

    Topics: Aclarubicin; Acute Disease; Antineoplastic Agents; Cytarabine; Daunorubicin; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Gene Expression; Genes, MDR; Humans; Lethal Dose 50; Leukemia, Myeloid; Mitoxantrone; Tumor Cells, Cultured

1998
Aclarubicin inhibits etoposide induced apoptosis through inhibition of RNA synthesis in P388 murine leukemic cells.
    Journal of experimental & clinical cancer research : CR, 1998, Volume: 17, Issue:4

    Topics: Aclarubicin; Animals; Antibiotics, Antineoplastic; Apoptosis; DNA Damage; DNA, Neoplasm; Drug Interactions; Etoposide; Flow Cytometry; G1 Phase; Leukemia P388; Mice; Neoplasm Proteins; Nucleic Acid Synthesis Inhibitors; RNA, Neoplasm; Tumor Cells, Cultured

1998
Molecular effects of topoisomerase II inhibitors in AML cell lines: correlation of apoptosis with topoisomerase II activity but not with DNA damage.
    Leukemia, 1999, Volume: 13, Issue:11

    Topics: Aclarubicin; Acute Disease; Antineoplastic Agents; Apoptosis; Cell Nucleus; Comet Assay; Daunorubicin; DNA; DNA Damage; DNA Topoisomerases, Type II; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Etoposide; fas Receptor; Genes, p53; Humans; Intercalating Agents; Leukemia, Myeloid; Mitochondria; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1999
F 11782, a dual inhibitor of topoisomerases I and II with an original mechanism of action in vitro, and markedly superior in vivo antitumour activity, relative to three other dual topoisomerase inhibitors, intoplicin, aclarubicin and TAS-103.
    Cancer chemotherapy and pharmacology, 2000, Volume: 46, Issue:2

    Topics: Aclarubicin; Aminoquinolines; Animals; Antineoplastic Agents; Cell Division; Enzyme Inhibitors; Etoposide; Humans; Indenes; Indoles; Leukemia L1210; Leukemia P388; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Naphthalenes; Pyrans; Pyridines; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Urinary Bladder Neoplasms

2000
Pretreatment leukaemia cell drug resistance is correlated to clinical outcome in acute myeloid leukaemia.
    European journal of haematology, 2001, Volume: 66, Issue:3

    Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neoplastic Stem Cells; Prognosis; Remission Induction; Survival Analysis; Thioguanine; Treatment Outcome; Tumor Cells, Cultured

2001
FAB M4 and high CD14 surface expression is associated with high cellular resistance to Ara-C and daunorubicin: implications for clinical outcome in acute myeloid leukaemia.
    European journal of haematology, 2001, Volume: 67, Issue:4

    Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Amsacrine; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cohort Studies; Cytarabine; Daunorubicin; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid; Leukemia, Myelomonocytic, Acute; Lipopolysaccharide Receptors; Male; Middle Aged; Mitoxantrone; Multivariate Analysis; Neoplastic Stem Cells; Thioguanine; Treatment Outcome

2001
BRCA1- and BRCA2-deficient cells are sensitive to etoposide-induced DNA double-strand breaks via topoisomerase II.
    Cancer research, 2007, Aug-01, Volume: 67, Issue:15

    Topics: Aclarubicin; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; BRCA1 Protein; BRCA2 Protein; Cells, Cultured; DNA Breaks, Double-Stranded; DNA Topoisomerases, Type II; Etoposide; Fibroblasts; Humans

2007
Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin.
    Nature communications, 2013, Volume: 4

    Topics: Aclarubicin; Animals; Anthracyclines; Antineoplastic Agents; Apoptosis; Blast Crisis; Cell Line, Tumor; Cell Survival; Chromatin; DNA; DNA Damage; Doxorubicin; Etoposide; Heart; Histones; Humans; Intercalating Agents; Leukemia, Myeloid, Acute; Mice; Mice, Nude; Nucleic Acid Conformation; Nucleosomes; Organ Specificity; Transcriptome

2013
Chemical profiling of the genome with anti-cancer drugs defines target specificities.
    Nature chemical biology, 2015, Volume: 11, Issue:7

    Topics: Aclarubicin; Antineoplastic Agents; Cell Line, Tumor; Chromatin; Daunorubicin; DNA Damage; DNA, Neoplasm; Etoposide; Gene Expression Regulation, Neoplastic; Genome, Human; Histones; Humans; Molecular Targeted Therapy; Neoplasms; Organ Specificity; Protein Transport; Structure-Activity Relationship; Topoisomerase Inhibitors; Topotecan

2015
Efficacy of common salvage chemotherapy regimens in patients with refractory or relapsed acute myeloid leukemia: A retrospective cohort study.
    Medicine, 2018, Volume: 97, Issue:39

    Topics: Aclarubicin; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cohort Studies; Cytarabine; Daunorubicin; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Harringtonines; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Retrospective Studies; Salvage Therapy; Survival Rate; Treatment Outcome; Vidarabine; Young Adult

2018