etoposide has been researched along with abt-737 in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (31.25) | 29.6817 |
| 2010's | 11 (68.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aridoss, G; Bleeker, NP; Hermanson, DL; Xing, C; Zhou, B | 1 |
| Anderson, MG; Chen, J; Elmore, SW; Fesik, SW; Morgan-Lappe, SE; Ng, SC; Rosenberg, SH; Sarthy, AV; Tahir, SK; Tse, C; Warner, RB; Yang, X | 1 |
| Biesterfeld, S; Hoffarth, S; Huber, C; Kröll, M; Schuler, M; Wesarg, E; Wiewrodt, R | 1 |
| Carlson, N; Dal Cin, P; Deng, J; Letai, A; Shipp, M; Takeyama, K | 1 |
| Cope, L; Daniel, VC; Dobromilskaya, I; Hann, CL; Hierman, JS; Lin, X; Murphy, SC; Rudin, CM; Sugar, EA; Watkins, DN; Wilburn, DL | 1 |
| Chew, E; Fairlie, WD; Grigg, AP; Huang, DC; Khaw, SL; Lee, EF; Mason, KD; Rayeroux, KC; Roberts, AW; Seymour, JF; Szer, J | 1 |
| Carrier, M; Cencic, R; Minden, M; Pelletier, J; Porco, JA; Trnkus, A | 1 |
| Bazan, F; Dixit, VM; Dornan, D; Eastham-Anderson, J; Ferrando, R; French, DM; Huang, DC; Huang, X; Lill, JR; Liu, J; Maecker, H; O'Rourke, K; Schwickart, M; Yue, P | 1 |
| Hadjidaniel, MD; Reynolds, CP | 1 |
| Clifford, SC; Coyle, B; Grundy, R; Levesley, J; Lindsey, JC; Lusher, ME | 1 |
| Anderson, DJ; Belmont, LD; Bouillet, P; Campbell, KJ; Cory, S; Fairlie, WD; Glaser, SP; Huang, DC; Khaw, SL; Lee, EF; Ludlam, MJ; Mérino, D; Phipson, B; Robati, M; Roberts, AW; Vandenberg, CJ; Wong, C; Yue, P | 1 |
| Biémont-Trescol, MC; Bonnefoy, N; Debaud, AL; Duc Dodon, M; Gazzolo, L; Hermine, O; Macaire, H; Mahieux, R; Mesnard, JM; Moncollin, V; Pierre, M; Riquet, A; Valentin, H | 1 |
| Borst, J; Rooswinkel, RW; van de Kooij, B; Verheij, M | 1 |
| Akagi, J; Darzynkiewicz, Z; Dobrucki, J; Errington, R; Kordon, M; Matuszek, A; Smith, PJ; Takeda, K; Wlodkowic, D; Zhao, H | 1 |
| Connis, N; Cope, L; Dobromilskaya, I; Gallia, GL; Gardner, EE; Hann, CL; Poirier, JT; Rudin, CM | 1 |
| Cha, HJ; Go, YH; Hong, SK; Kwon, OS; Kwon, SJ; Oh, E | 1 |
16 other study(ies) available for etoposide and abt-737
| Article | Year |
|---|---|
Structure-activity relationship (SAR) study of ethyl 2-amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (CXL017) and the potential of the lead against multidrug resistance in cancer treatment.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzopyrans; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Proto-Oncogene Proteins c-bcl-2; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Structure-Activity Relationship | 2012 |
Influence of Bcl-2 family members on the cellular response of small-cell lung cancer cell lines to ABT-737.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Biphenyl Compounds; Carboplatin; Carcinoma, Small Cell; Cell Growth Processes; Cell Line, Tumor; Down-Regulation; Drug Synergism; Etoposide; Humans; Lung Neoplasms; Membrane Proteins; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Nitrophenols; Piperazines; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; RNA, Small Interfering; Sulfonamides; Transfection; Up-Regulation | 2007 |
Targeting BCL-2 family proteins to overcome drug resistance in non-small cell lung cancer.
Topics: Antineoplastic Agents; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; Biphenyl Compounds; Butylated Hydroxytoluene; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Doxorubicin; Drug Resistance, Neoplasm; Electrophoresis; Etoposide; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; Immunohistochemistry; Lung Neoplasms; Mitochondria; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Nitrophenols; Paclitaxel; Permeability; Piperazines; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Sulfonamides | 2007 |
BH3 profiling identifies three distinct classes of apoptotic blocks to predict response to ABT-737 and conventional chemotherapeutic agents.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; BH3 Interacting Domain Death Agonist Protein; Biphenyl Compounds; Blotting, Western; Doxorubicin; Etoposide; Humans; Immunoblotting; Immunoprecipitation; Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Membrane Proteins; Nitrophenols; Piperazines; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Sulfonamides; Tumor Cells, Cultured; Vincristine | 2007 |
Therapeutic efficacy of ABT-737, a selective inhibitor of BCL-2, in small cell lung cancer.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biphenyl Compounds; Carcinoma, Small Cell; Caspase 3; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Activation; Etoposide; Humans; Lung Neoplasms; Mice; Mice, Nude; Nitrophenols; Piperazines; Proto-Oncogene Proteins c-bcl-2; Sulfonamides; Xenograft Model Antitumor Assays | 2008 |
The BH3 mimetic compound, ABT-737, synergizes with a range of cytotoxic chemotherapy agents in chronic lymphocytic leukemia.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; bcl-X Protein; Biphenyl Compounds; Dexamethasone; Doxorubicin; Drug Synergism; Etoposide; Humans; In Vitro Techniques; Leukemia, Lymphocytic, Chronic, B-Cell; Molecular Mimicry; Nitrophenols; Piperazines; Prognosis; Proto-Oncogene Proteins c-bcl-2; Sulfonamides; Vidarabine | 2009 |
Synergistic effect of inhibiting translation initiation in combination with cytotoxic agents in acute myelogenous leukemia cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biphenyl Compounds; Cell Line, Tumor; Cytarabine; Cytotoxins; Daunorubicin; Drug Evaluation, Preclinical; Drug Synergism; Etoposide; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Models, Biological; Nitrophenols; Peptide Initiation Factors; Piperazines; Protein Biosynthesis; Protein Synthesis Inhibitors; Sulfonamides; Triterpenes; U937 Cells | 2010 |
Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival.
Topics: Animals; Apoptosis; Biphenyl Compounds; Cell Line; Cell Line, Tumor; Cell Survival; DNA Damage; Docetaxel; Etoposide; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Half-Life; Humans; Lysine; Mice; Mice, SCID; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasms; Nitrophenols; Phosphorylation; Piperazines; Polyubiquitin; Prognosis; Protein Binding; Protein Stability; Proto-Oncogene Proteins c-bcl-2; RNA Interference; Sulfonamides; Taxoids; Ubiquitin Thiolesterase; Ubiquitination; Ultraviolet Rays; Xenograft Model Antitumor Assays | 2010 |
Antagonism of cytotoxic chemotherapy in neuroblastoma cell lines by 13-cis-retinoic acid is mediated by the antiapoptotic Bcl-2 family proteins.
Topics: Alkylating Agents; Apoptosis; Biphenyl Compounds; Cell Line, Tumor; Cisplatin; Cytochromes c; Cytoprotection; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Isotretinoin; Melphalan; Membrane Potential, Mitochondrial; Mitochondria; Neuroblastoma; Nitrophenols; Piperazines; Protective Agents; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; Signal Transduction; Sulfonamides; Topoisomerase Inhibitors; Tumor Suppressor Protein p53 | 2010 |
RASSF1A and the BH3-only mimetic ABT-737 promote apoptosis in pediatric medulloblastoma cell lines.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Biphenyl Compounds; Blotting, Western; Caspases; Cell Line, Tumor; Cerebellar Neoplasms; Child; Cisplatin; Etoposide; Humans; Immunoenzyme Techniques; Medulloblastoma; Nitrophenols; Piperazines; Proto-Oncogene Proteins c-bcl-2; Sulfonamides; Tumor Suppressor Proteins | 2011 |
Bcl-2, Bcl-x(L), and Bcl-w are not equivalent targets of ABT-737 and navitoclax (ABT-263) in lymphoid and leukemic cells.
Topics: Aniline Compounds; Animals; Apoptosis Regulatory Proteins; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Bcl-2-Like Protein 11; bcl-X Protein; Biphenyl Compounds; Cell Death; Cytoprotection; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Leukemia; Lymphoma; Membrane Proteins; Mice; Molecular Targeted Therapy; Mutant Proteins; Myeloid Cell Leukemia Sequence 1 Protein; Nitrophenols; Piperazines; Protein Binding; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Sulfonamides | 2012 |
Tax protein-induced expression of antiapoptotic Bfl-1 protein contributes to survival of human T-cell leukemia virus type 1 (HTLV-1)-infected T-cells.
Topics: Adult; Antineoplastic Agents, Phytogenic; Basic-Leucine Zipper Transcription Factors; bcl-X Protein; Biphenyl Compounds; CD4-Positive T-Lymphocytes; Cell Survival; DNA-Binding Proteins; Etoposide; Female; Gene Knockdown Techniques; Gene Products, tax; Genes, jun; HeLa Cells; Human T-lymphotropic virus 1; Humans; Leukemia-Lymphoma, Adult T-Cell; Ligases; Male; Minor Histocompatibility Antigens; NF-kappa B p50 Subunit; Nitrophenols; Nuclear Proteins; Piperazines; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins c-rel; Retroviridae Proteins; Sulfonamides; Transcription Factor RelB; Transcription, Genetic; Viral Proteins | 2012 |
Bcl-2 is a better ABT-737 target than Bcl-xL or Bcl-w and only Noxa overcomes resistance mediated by Mcl-1, Bfl-1, or Bcl-B.
Topics: Antineoplastic Agents; Apoptosis Regulatory Proteins; bcl-X Protein; Biphenyl Compounds; Boronic Acids; Bortezomib; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; Etoposide; Humans; Minor Histocompatibility Antigens; Myeloid Cell Leukemia Sequence 1 Protein; Nitrophenols; Piperazines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Binding; Proto-Oncogene Proteins c-bcl-2; Pyrazines; Sulfonamides; T-Lymphocytes; Tumor Suppressor Protein p53 | 2012 |
Real-time cell viability assays using a new anthracycline derivative DRAQ7®.
Topics: Anthracyclines; Apoptosis; Benzamides; Biphenyl Compounds; Cell Line, Tumor; Cell Survival; Dactinomycin; DNA Damage; Etoposide; Flow Cytometry; Fluorescent Dyes; Histones; Humans; Inhibitory Concentration 50; Membrane Potential, Mitochondrial; Nitrophenols; Piperazines; Rhodamines; Staurosporine; Sulfonamides; Sulfones | 2013 |
Rapamycin rescues ABT-737 efficacy in small cell lung cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biphenyl Compounds; Cell Line, Tumor; Drug Synergism; Etoposide; Female; Humans; Lung Neoplasms; Mice; Mice, SCID; Nitrophenols; Piperazines; Proto-Oncogene Proteins c-bcl-2; Random Allocation; Sirolimus; Small Cell Lung Carcinoma; Sulfonamides; Xenograft Model Antitumor Assays | 2014 |
BCL2 induced by LAMTOR3/MAPK is a druggable target of chemoradioresistance in mesenchymal lung cancer.
Topics: A549 Cells; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenocarcinoma of Lung; Aniline Compounds; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Biphenyl Compounds; Cell Proliferation; Cell Survival; Chemoradiotherapy; Diphenylamine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Molecular Mimicry; Nitrophenols; Peptide Fragments; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Radiation Tolerance; RNA Interference; Signal Transduction; Sulfonamides; Transfection; Up-Regulation | 2017 |