etomoxir has been researched along with troglitazone in 2 studies
| Studies (etomoxir) | Trials (etomoxir) | Recent Studies (post-2010) (etomoxir) | Studies (troglitazone) | Trials (troglitazone) | Recent Studies (post-2010) (troglitazone) |
|---|---|---|---|---|---|
| 260 | 8 | 93 | 1,857 | 146 | 287 |
| Protein | Taxonomy | etomoxir (IC50) | troglitazone (IC50) |
|---|---|---|---|
| Bile salt export pump | Rattus norvegicus (Norway rat) | 3.9 | |
| Bile salt export pump | Homo sapiens (human) | 5.05 | |
| Carbonic anhydrase 2 | Homo sapiens (human) | 0.97 | |
| Adenosine receptor A3 | Homo sapiens (human) | 5.208 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 4 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 5.208 | |
| Thromboxane-A synthase | Homo sapiens (human) | 2.966 | |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | 2.07 | |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | 1.238 | |
| Peroxisome proliferator-activated receptor gamma | Homo sapiens (human) | 1.03 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 1.312 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 5.208 | |
| ATP-binding cassette sub-family C member 8 | Homo sapiens (human) | 1.285 | |
| ATP-sensitive inward rectifier potassium channel 11 | Homo sapiens (human) | 1.285 | |
| Indoleamine 2,3-dioxygenase 2 | Mus musculus (house mouse) | 4.5 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y | 1 |
2 other study(ies) available for etomoxir and troglitazone
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index | 2014 |