Page last updated: 2024-09-03

etomoxir and trimetazidine

etomoxir has been researched along with trimetazidine in 14 studies

Compound Research Comparison

Studies
(etomoxir)
Trials
(etomoxir)
Recent Studies (post-2010)
(etomoxir)
Studies
(trimetazidine)
Trials
(trimetazidine)
Recent Studies (post-2010) (trimetazidine)
260893970226341

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.14)18.2507
2000's7 (50.00)29.6817
2010's4 (28.57)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Arduini, A; Ceccarelli, SM; Chomienne, O; Gubler, M1
Chirkov, YY; Chirkova, LP; Horowitz, JD; Kennedy, JA; Murphy, GA; Willoughby, SR1
Maisch, B; Rupp, H; Zarain-Herzberg, A1
Frenneaux, M; Horowitz, J; Lee, L1
Inglis, S; Stewart, S1
Abozguia, K; Clarke, K; Frenneaux, M; Lee, L1
Celik, T; Iyisoy, A; Jata, B; Kursaklioglu, H1
Marazzi, G; Rosano, GM; Volterrani, M1
Di Napoli, P1
Mellana, WM; Mohan, D; Palaniswamy, C; Selvaraj, DR1
Heggermont, WA; Heymans, S; Papageorgiou, AP; van Bilsen, M1
Devarakonda, T; Fang, X; Ma, Y; Salloum, FN; Spiegel, S; Wang, W; Wang, XY; Zhou, H1
Dash, D; Ekhlak, M; Kailashiya, V; Kulkarni, PP; Singh, N; Singh, V1

Reviews

6 review(s) available for etomoxir and trimetazidine

ArticleYear
The use of partial fatty acid oxidation inhibitors for metabolic therapy of angina pectoris and heart failure.
    Herz, 2002, Volume: 27, Issue:7

    Topics: Acetanilides; Angina Pectoris; Animals; Calcium; Cardiovascular Agents; Clinical Trials as Topic; Enzyme Inhibitors; Epoxy Compounds; Fatty Acids; Gene Expression; Glucose; Heart Failure; Humans; Hypoglycemic Agents; Methylhydrazines; Myocytes, Cardiac; Oxidation-Reduction; Piperazines; Ranolazine; Rats; Rats, Wistar; Sarcoplasmic Reticulum; Trimetazidine; Up-Regulation; Vasodilator Agents

2002
Metabolic manipulation in ischaemic heart disease, a novel approach to treatment.
    European heart journal, 2004, Volume: 25, Issue:8

    Topics: Acetanilides; Adrenergic beta-Antagonists; Angina Pectoris; Cardiovascular Agents; Drug Therapy, Combination; Enzyme Inhibitors; Epoxy Compounds; Glucose; Humans; Hypoglycemic Agents; Insulin; Myocardial Ischemia; Myocardium; Perhexiline; Piperazines; Potassium; Ranolazine; Trimetazidine

2004
Metabolic therapeutics in angina pectoris: history revisited with perhexiline.
    European journal of cardiovascular nursing, 2006, Volume: 5, Issue:2

    Topics: Acetanilides; Angina Pectoris; Calcium Channel Blockers; Cardiovascular Agents; Carnitine O-Palmitoyltransferase; Drug Monitoring; Epoxy Compounds; Fatty Acids; Half-Life; Humans; Metabolic Clearance Rate; Nurse's Role; Nursing Assessment; Patient Education as Topic; Patient Selection; Perhexiline; Piperazines; Randomized Controlled Trials as Topic; Ranolazine; Treatment Outcome; Trimetazidine; Vasodilator Agents

2006
Modification of myocardial substrate use as a therapy for heart failure.
    Nature clinical practice. Cardiovascular medicine, 2006, Volume: 3, Issue:9

    Topics: Acetanilides; Adrenergic beta-Antagonists; Animals; Cardiac Output, Low; Cardiovascular Agents; Energy Metabolism; Epoxy Compounds; Fatty Acids, Nonesterified; Glycine; Heart; Humans; Myocardium; Oxygen; Perhexiline; Piperazines; Ranolazine; Trimetazidine

2006
Metabolic modulation: a new therapeutic target in treatment of heart failure.
    American journal of therapeutics, 2011, Volume: 18, Issue:6

    Topics: Acetanilides; Carnitine O-Palmitoyltransferase; Enzyme Inhibitors; Epoxy Compounds; Fatty Acids; Glucose; Heart Failure; Humans; Mitochondria, Heart; Myocytes, Cardiac; Perhexiline; Piperazines; Ranolazine; Trimetazidine; Vasodilator Agents

2011
Metabolic support for the heart: complementary therapy for heart failure?
    European journal of heart failure, 2016, Volume: 18, Issue:12

    Topics: Acetyl-CoA C-Acyltransferase; Cardiovascular Agents; Carnitine; Carnitine O-Palmitoyltransferase; Dichloroacetic Acid; Energy Metabolism; Enzyme Inhibitors; Epoxy Compounds; Fatty Acids; Glucose; Heart Failure; Humans; Myocardium; Myocytes, Cardiac; Oxidation-Reduction; Perhexiline; Ranolazine; Stroke Volume; Trimetazidine

2016

Other Studies

8 other study(ies) available for etomoxir and trimetazidine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Carnitine palmitoyltransferase (CPT) modulators: a medicinal chemistry perspective on 35 years of research.
    Journal of medicinal chemistry, 2011, May-12, Volume: 54, Issue:9

    Topics: Animals; Carnitine; Carnitine O-Palmitoyltransferase; Catalytic Domain; Diabetes Mellitus, Type 2; Energy Metabolism; Enzyme Activators; Ethylene Oxide; Heart Failure; Humans; Insulin Resistance; Isoenzymes; Lipid Metabolism; Myocardial Ischemia; Organ Specificity; Protein Conformation; Sequence Homology, Amino Acid; Stereoisomerism

2011
Inhibition of long-chain fatty acid metabolism does not affect platelet aggregation responses.
    European journal of pharmacology, 1998, Sep-04, Volume: 356, Issue:2-3

    Topics: Adult; Aged; Amiodarone; Blood Platelets; Cardiovascular Agents; Carnitine O-Palmitoyltransferase; Case-Control Studies; Enzyme Inhibitors; Epoxy Compounds; Fatty Acids; Female; Humans; Male; Middle Aged; Perhexiline; Platelet Aggregation; Trimetazidine; Vasodilator Agents

1998
Metabolic agents in the management of diabetic coronary patients: a new era.
    International journal of cardiology, 2008, Jun-23, Volume: 127, Issue:1

    Topics: Carnitine; Coronary Disease; Diabetes Mellitus; Diabetic Angiopathies; Dichloroacetic Acid; Enzyme Inhibitors; Epoxy Compounds; Humans; Perhexiline; Trimetazidine; Vasodilator Agents; Vitamin B Complex

2008
Metabolic agents in the management of diabetic coronary patients: a new era.
    International journal of cardiology, 2008, Jun-23, Volume: 127, Issue:1

    Topics: Acetanilides; Citric Acid Cycle; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Dichloroacetic Acid; Enzyme Inhibitors; Epoxy Compounds; Humans; Insulin Resistance; Perhexiline; Piperazines; Ranolazine; Trimetazidine; Vasodilator Agents

2008
The metabolic treatment of coronary artery disease and heart failure.
    Current pharmaceutical design, 2009, Volume: 15, Issue:8

    Topics: Carnitine O-Palmitoyltransferase; Coronary Artery Disease; Epoxy Compounds; Heart Failure; Humans; Perhexiline; Trimetazidine; Vasodilator Agents

2009
Functional analysis of molecular and pharmacological modulators of mitochondrial fatty acid oxidation.
    Scientific reports, 2020, 01-29, Volume: 10, Issue:1

    Topics: Animals; Energy Metabolism; Epoxy Compounds; Fatty Acids; Female; Glycine; Humans; MCF-7 Cells; Mice; Mice, Inbred C57BL; Mitochondria; Oxidation-Reduction; PPAR alpha; Ranolazine; Trimetazidine

2020
Fatty acid oxidation fuels agonist-induced platelet activation and thrombus formation: Targeting β-oxidation of fatty acids as an effective anti-platelet strategy.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2023, Volume: 37, Issue:2

    Topics: Adenosine Triphosphate; Animals; Blood Platelets; Collagen; Fatty Acids; Glucose; Mice; Oxidative Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombosis; Trimetazidine

2023