Compounds > etomoxir
Page last updated: 2024-09-03

etomoxir and sirolimus

etomoxir has been researched along with sirolimus in 3 studies

Compound Research Comparison

Studies
(etomoxir)		Trials
(etomoxir)		Recent Studies (post-2010)
(etomoxir)		Studies
(sirolimus)		Trials
(sirolimus)		Recent Studies (post-2010) (sirolimus)
26089320,7112,36811,516

Protein Interaction Comparison

ProteinTaxonomyetomoxir (IC50)sirolimus (IC50)
Bile salt export pumpHomo sapiens (human)10
ATP-dependent translocase ABCB1Homo sapiens (human)1.25
Cytochrome P450 3A4Homo sapiens (human)2
Cytochrome P450 2C9 Homo sapiens (human)2
Peptidyl-prolyl cis-trans isomerase FKBP1AMus musculus (house mouse)0.001
Cytochrome P450 2C19Homo sapiens (human)4
Serine/threonine-protein kinase mTORHomo sapiens (human)0.0897
Peptidyl-prolyl cis-trans isomerase FKBP1AHomo sapiens (human)0.0042
Regulatory-associated protein of mTORHomo sapiens (human)0.225
Target of rapamycin complex subunit LST8Homo sapiens (human)0.225
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)1.9
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)1.1

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Cruz-Garcia, L; Gutiérrez, J; Navarro, I; Sánchez-Gurmaches, J1
Feng, Y; Huang, Y; Wang, F; Wang, P; Wang, Y1

Other Studies

3 other study(ies) available for etomoxir and sirolimus

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Endocrine control of oleic acid and glucose metabolism in rainbow trout (Oncorhynchus mykiss) muscle cells in culture.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2010, Volume: 299, Issue:2

    Topics: Animals; Carbon Dioxide; Carnitine O-Palmitoyltransferase; Catecholamines; Cells, Cultured; Energy Metabolism; Epoxy Compounds; Glucose; Glycogen; Hypoglycemic Agents; Insulin; Insulin-Like Growth Factor I; Intracellular Signaling Peptides and Proteins; Muscle Fibers, Skeletal; Oleic Acid; Oncorhynchus mykiss; Oxidation-Reduction; PPAR gamma; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Rosiglitazone; Sirolimus; Thiazolidinediones; TOR Serine-Threonine Kinases; Triglycerides

2010
Short-Chain Fatty Acids Manifest Stimulative and Protective Effects on Intestinal Barrier Function Through the Inhibition of NLRP3 Inflammasome and Autophagy.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 49, Issue:1

    Topics: Autophagy; Beclin-1; Caco-2 Cells; Cytokines; Energy Metabolism; Epoxy Compounds; Fatty Acids, Volatile; Humans; Hydroxamic Acids; Inflammasomes; Intestinal Mucosa; Lipopolysaccharides; Microtubule-Associated Proteins; NLR Family, Pyrin Domain-Containing 3 Protein; Occludin; Permeability; Reactive Oxygen Species; Sirolimus; Tight Junctions; Zonula Occludens-1 Protein

2018