etomoxir has been researched along with perhexiline in 11 studies
| Studies (etomoxir) | Trials (etomoxir) | Recent Studies (post-2010) (etomoxir) | Studies (perhexiline) | Trials (perhexiline) | Recent Studies (post-2010) (perhexiline) |
|---|---|---|---|---|---|
| 260 | 8 | 93 | 572 | 92 | 83 |
| Protein | Taxonomy | etomoxir (IC50) | perhexiline (IC50) |
|---|---|---|---|
| Epidermal growth factor receptor | Homo sapiens (human) | 1.4852 | |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | 4.064 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 3.2942 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 3.5919 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 1.0932 | |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | 6.38 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 0.9408 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 2.7105 | |
| D | Rattus norvegicus (Norway rat) | 7.7625 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 7.7625 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 3.1186 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 7.7625 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 7.7625 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 3.2942 | |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | 7.7625 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 7.7687 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 2.5992 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 6 (54.55) | 29.6817 |
| 2010's | 4 (36.36) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arduini, A; Ceccarelli, SM; Chomienne, O; Gubler, M | 1 |
| Chirkov, YY; Chirkova, LP; Horowitz, JD; Kennedy, JA; Murphy, GA; Willoughby, SR | 1 |
| Frenneaux, M; Horowitz, J; Lee, L | 1 |
| Inglis, S; Stewart, S | 1 |
| Abozguia, K; Clarke, K; Frenneaux, M; Lee, L | 1 |
| Celik, T; Iyisoy, A; Jata, B; Kursaklioglu, H | 1 |
| Marazzi, G; Rosano, GM; Volterrani, M | 1 |
| Di Napoli, P | 1 |
| Mellana, WM; Mohan, D; Palaniswamy, C; Selvaraj, DR | 1 |
| Broom, OJ; Nordström, A; Stäubert, C | 1 |
| Heggermont, WA; Heymans, S; Papageorgiou, AP; van Bilsen, M | 1 |
5 review(s) available for etomoxir and perhexiline
| Article | Year |
|---|---|
Metabolic manipulation in ischaemic heart disease, a novel approach to treatment.
Topics: Acetanilides; Adrenergic beta-Antagonists; Angina Pectoris; Cardiovascular Agents; Drug Therapy, Combination; Enzyme Inhibitors; Epoxy Compounds; Glucose; Humans; Hypoglycemic Agents; Insulin; Myocardial Ischemia; Myocardium; Perhexiline; Piperazines; Potassium; Ranolazine; Trimetazidine | 2004 |
Metabolic therapeutics in angina pectoris: history revisited with perhexiline.
Topics: Acetanilides; Angina Pectoris; Calcium Channel Blockers; Cardiovascular Agents; Carnitine O-Palmitoyltransferase; Drug Monitoring; Epoxy Compounds; Fatty Acids; Half-Life; Humans; Metabolic Clearance Rate; Nurse's Role; Nursing Assessment; Patient Education as Topic; Patient Selection; Perhexiline; Piperazines; Randomized Controlled Trials as Topic; Ranolazine; Treatment Outcome; Trimetazidine; Vasodilator Agents | 2006 |
Modification of myocardial substrate use as a therapy for heart failure.
Topics: Acetanilides; Adrenergic beta-Antagonists; Animals; Cardiac Output, Low; Cardiovascular Agents; Energy Metabolism; Epoxy Compounds; Fatty Acids, Nonesterified; Glycine; Heart; Humans; Myocardium; Oxygen; Perhexiline; Piperazines; Ranolazine; Trimetazidine | 2006 |
Metabolic modulation: a new therapeutic target in treatment of heart failure.
Topics: Acetanilides; Carnitine O-Palmitoyltransferase; Enzyme Inhibitors; Epoxy Compounds; Fatty Acids; Glucose; Heart Failure; Humans; Mitochondria, Heart; Myocytes, Cardiac; Perhexiline; Piperazines; Ranolazine; Trimetazidine; Vasodilator Agents | 2011 |
Metabolic support for the heart: complementary therapy for heart failure?
Topics: Acetyl-CoA C-Acyltransferase; Cardiovascular Agents; Carnitine; Carnitine O-Palmitoyltransferase; Dichloroacetic Acid; Energy Metabolism; Enzyme Inhibitors; Epoxy Compounds; Fatty Acids; Glucose; Heart Failure; Humans; Myocardium; Myocytes, Cardiac; Oxidation-Reduction; Perhexiline; Ranolazine; Stroke Volume; Trimetazidine | 2016 |
6 other study(ies) available for etomoxir and perhexiline
| Article | Year |
|---|---|
Carnitine palmitoyltransferase (CPT) modulators: a medicinal chemistry perspective on 35 years of research.
Topics: Animals; Carnitine; Carnitine O-Palmitoyltransferase; Catalytic Domain; Diabetes Mellitus, Type 2; Energy Metabolism; Enzyme Activators; Ethylene Oxide; Heart Failure; Humans; Insulin Resistance; Isoenzymes; Lipid Metabolism; Myocardial Ischemia; Organ Specificity; Protein Conformation; Sequence Homology, Amino Acid; Stereoisomerism | 2011 |
Inhibition of long-chain fatty acid metabolism does not affect platelet aggregation responses.
Topics: Adult; Aged; Amiodarone; Blood Platelets; Cardiovascular Agents; Carnitine O-Palmitoyltransferase; Case-Control Studies; Enzyme Inhibitors; Epoxy Compounds; Fatty Acids; Female; Humans; Male; Middle Aged; Perhexiline; Platelet Aggregation; Trimetazidine; Vasodilator Agents | 1998 |
Metabolic agents in the management of diabetic coronary patients: a new era.
Topics: Carnitine; Coronary Disease; Diabetes Mellitus; Diabetic Angiopathies; Dichloroacetic Acid; Enzyme Inhibitors; Epoxy Compounds; Humans; Perhexiline; Trimetazidine; Vasodilator Agents; Vitamin B Complex | 2008 |
Metabolic agents in the management of diabetic coronary patients: a new era.
Topics: Acetanilides; Citric Acid Cycle; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Dichloroacetic Acid; Enzyme Inhibitors; Epoxy Compounds; Humans; Insulin Resistance; Perhexiline; Piperazines; Ranolazine; Trimetazidine; Vasodilator Agents | 2008 |
The metabolic treatment of coronary artery disease and heart failure.
Topics: Carnitine O-Palmitoyltransferase; Coronary Artery Disease; Epoxy Compounds; Heart Failure; Humans; Perhexiline; Trimetazidine; Vasodilator Agents | 2009 |
Hydroxycarboxylic acid receptors are essential for breast cancer cells to control their lipid/fatty acid metabolism.
Topics: Breast Neoplasms; Carnitine O-Palmitoyltransferase; Cell Death; Cell Line, Tumor; Cell Proliferation; Chromatography, Liquid; Enzyme Inhibitors; Epoxy Compounds; Fatty Acids; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; HEK293 Cells; Humans; Lipid Metabolism; Oxidation-Reduction; Perhexiline; Receptors, G-Protein-Coupled; Receptors, Nicotinic; RNA Interference; RNA, Messenger; Signal Transduction; Tandem Mass Spectrometry; Time Factors; Transfection; Tumor Cells, Cultured | 2015 |