etomoxir has been researched along with palmitic acid in 23 studies
| Studies (etomoxir) | Trials (etomoxir) | Recent Studies (post-2010) (etomoxir) | Studies (palmitic acid) | Trials (palmitic acid) | Recent Studies (post-2010) (palmitic acid) |
|---|---|---|---|---|---|
| 260 | 8 | 93 | 6,794 | 159 | 2,458 |
| Protein | Taxonomy | etomoxir (IC50) | palmitic acid (IC50) |
|---|---|---|---|
| Toll-like receptor 2 | Homo sapiens (human) | 5 | |
| Fatty acid-binding protein, intestinal | Homo sapiens (human) | 1.7 | |
| Fatty acid-binding protein, adipocyte | Homo sapiens (human) | 0.93 | |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | 8.8 | |
| Fatty acid-binding protein 5 | Homo sapiens (human) | 1.2 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (39.13) | 18.2507 |
| 2000's | 11 (47.83) | 29.6817 |
| 2010's | 2 (8.70) | 24.3611 |
| 2020's | 1 (4.35) | 2.80 |
| Authors | Studies |
|---|---|
| Agius, L; Peak, M; Sherratt, SA | 1 |
| Chiesi, M; Grueninger, S; Lesniak, W; Schaefer, C | 1 |
| Chen, S; Foster, DW; McGarry, JD; Ogawa, A; Ohneda, M; Unger, RH | 1 |
| Grill, VE; Zhou, YP | 1 |
| Agius, L; Pogson, CI; Sherratt, HA; Spurway, TD | 1 |
| Elliott, KR; New, KJ; Quant, PA | 1 |
| Brivet, M; Divry, P; Mathieu, M; Nada, M; Roe, C; Vianey-Saban, C; Zabot, MT | 1 |
| Alam, N; Saggerson, ED | 1 |
| Elliott, KR; Krauss, S; New, KJ; Quant, PA | 1 |
| Khan, M; Sandhir, R; Singh, I | 1 |
| Cnop, M; Eizirik, DL; Hannaert, JC; Hoorens, A; Pipeleers, DG | 1 |
| Antinozzi, PA; Asins, G; Hegardt, FG; Herrero, L; Ishihara, H; Maechler, P; Rubí, B; Serra, D; Wollheim, CB | 1 |
| Berge, K; Berge, RK; Bohov, P; Madsen, L; Tronstad, KJ | 1 |
| Cheng, H; Sharp, GW; Straub, SG | 1 |
| Asins, G; Bentebibel, A; Gómez-Puertas, P; Hegardt, FG; Herrero, L; López-Viñas, E; Sebastián, D; Serra, D | 1 |
| Hermansen, K; Hong, J; Jeppesen, PB; Nordentoft, I | 1 |
| Cooksey, RC; Landaker, E; McClain, D; Park, J; Patti, ME; Ruddock, MW; Stein, A | 1 |
| Chen, ZP; Dzamko, N; Jørgensen, SB; Kemp, BE; Lynch, GS; Macaulay, SL; Michell, BJ; Oakhill, JS; Ryall, JG; Schertzer, JD; Steel, R; Steinberg, GR; Watt, MJ; Wee, S | 1 |
| Masterson, C; Wood, C | 1 |
| Downs, SM; Klinger, J; Mosey, JL | 1 |
| Choi, SE; Han, SJ; Jung, IR; Kang, Y; Kim, DJ; Kim, HJ; Lee, JH; Lee, KW; Lee, SJ; Lee, SM | 1 |
| Krisher, RL; Paczkowski, M; Schoolcraft, WB | 1 |
| Hou, Y; Liu, S; Song, Q; Song, W; Tan, H; Wang, Y; Zhou, T | 1 |
23 other study(ies) available for etomoxir and palmitic acid
| Article | Year |
|---|---|
Differences between human, rat and guinea pig hepatocyte cultures. A comparative study of their rates of beta-oxidation and esterification of palmitate and their sensitivity to R-etomoxir.
Topics: Animals; Cells, Cultured; Disease Models, Animal; Epoxy Compounds; Esterification; Guinea Pigs; Humans; Hypoglycemic Agents; Liver; Male; Oxidation-Reduction; Palmitic Acid; Palmitic Acids; Rats; Rats, Inbred Strains; Species Specificity; Stereoisomerism | 1991 |
Effect of alpha adrenergic stimulation and carnitine palmitoyl transferase I inhibition on hypertrophying adult rat cardiomyocytes in culture.
Topics: Animals; Atrial Natriuretic Factor; Base Sequence; Cardiomegaly; Cell Division; Cells, Cultured; DNA; Epoxy Compounds; Gene Expression; Glucose; Molecular Sequence Data; Myocardium; Oxidation-Reduction; Palmitic Acid; Palmitic Acids; Phenylalanine; Phenylephrine; Protein Biosynthesis; Rats; Sodium Channels | 1995 |
More direct evidence for a malonyl-CoA-carnitine palmitoyltransferase I interaction as a key event in pancreatic beta-cell signaling.
Topics: Animals; ATP Citrate (pro-S)-Lyase; Carnitine O-Palmitoyltransferase; Citrates; Epoxy Compounds; Glucose; Hypoglycemic Agents; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Malonyl Coenzyme A; Palmitates; Palmitic Acid; Palmitic Acids; Rats; Rats, Sprague-Dawley; Signal Transduction; Stearic Acids; Time Factors | 1994 |
Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle.
Topics: Animals; Caprylates; Carnitine O-Palmitoyltransferase; Cells, Cultured; Epoxy Compounds; Ethanol; Fatty Acids, Nonesterified; Glucose; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Kinetics; Male; Oleic Acid; Oleic Acids; Palmitic Acid; Palmitic Acids; Proinsulin; Protein Biosynthesis; Proteins; Rats; Rats, Sprague-Dawley; Time Factors | 1994 |
The flux control coefficient of carnitine palmitoyltransferase I on palmitate beta-oxidation in rat hepatocyte cultures.
Topics: Animals; Carnitine O-Palmitoyltransferase; Cells, Cultured; Enzyme Inhibitors; Epoxy Compounds; Liver; Male; Oxidation-Reduction; Palmitic Acid; Rats; Rats, Wistar; Stereoisomerism | 1997 |
Quantitative analysis of control exerted by mitochondrial outer membrane carnitine palmitoyltransferase over carbon fluxes from palmitate in hepatocytes isolated from suckling rats.
Topics: Aging; Animals; Animals, Suckling; Carnitine O-Palmitoyltransferase; Cells, Cultured; Enzyme Inhibitors; Epoxy Compounds; Intracellular Membranes; Liver; Mitochondria, Liver; Palmitic Acid; Rats; Rats, Wistar | 1997 |
Mitochondrial very-long-chain acyl-coenzyme A dehydrogenase deficiency: clinical characteristics and diagnostic considerations in 30 patients.
Topics: Acyl-CoA Dehydrogenase, Long-Chain; Carnitine O-Palmitoyltransferase; Cells, Cultured; Enzyme Inhibitors; Epoxy Compounds; Fatty Acids; Female; Humans; Lipid Metabolism, Inborn Errors; Mitochondria; Oxidation-Reduction; Palmitic Acid; Pregnancy; Prenatal Diagnosis; Skin | 1998 |
Malonyl-CoA and the regulation of fatty acid oxidation in soleus muscle.
Topics: Acyl Coenzyme A; Animals; ATP Citrate (pro-S)-Lyase; Carboxy-Lyases; Carnitine O-Palmitoyltransferase; Enzyme Inhibitors; Epoxy Compounds; Fatty Acid Synthases; Glucose; In Vitro Techniques; Kinetics; Malate Dehydrogenase; Male; Malonyl Coenzyme A; Models, Biological; Muscle, Skeletal; Oxidation-Reduction; Palmitic Acid; Rats; Rats, Sprague-Dawley; Regression Analysis | 1998 |
Comparisons of flux control exerted by mitochondrial outer-membrane carnitine palmitoyltransferase over ketogenesis in hepatocytes and mitochondria isolated from suckling or adult rats.
Topics: Animals; Animals, Suckling; Carbon Dioxide; Carnitine; Carnitine O-Palmitoyltransferase; Cells, Cultured; Energy Metabolism; Enzyme Inhibitors; Epoxy Compounds; Ketone Bodies; Liver; Malonyl Coenzyme A; Membrane Proteins; Mitochondria, Liver; Palmitic Acid; Palmitoyl Coenzyme A; Palmitoylcarnitine; Rats; Rats, Wistar | 1999 |
Identification of the pathway of alpha-oxidation of cerebronic acid in peroxisomes.
Topics: Animals; Carbon Dioxide; Catalase; Cell Line; Electron Transport Complex IV; Epoxy Compounds; Fatty Acids; Fatty Acids, Unsaturated; Fibroblasts; Humans; NADH Dehydrogenase; Neuroglia; Oxygen; Palmitic Acid; Peroxisomal Disorders; Peroxisomes; Rats; Rats, Sprague-Dawley; Skin | 2000 |
Inverse relationship between cytotoxicity of free fatty acids in pancreatic islet cells and cellular triglyceride accumulation.
Topics: Animals; Apoptosis; Carnitine O-Palmitoyltransferase; Cell Survival; Cells, Cultured; Cytoplasm; Enzyme Inhibitors; Epoxy Compounds; Fatty Acids, Nonesterified; Islets of Langerhans; Kinetics; Male; Oleic Acid; Palmitic Acid; Palmitic Acids; Rats; Rats, Wistar; Time Factors; Triglycerides | 2001 |
Adenovirus-mediated overexpression of liver carnitine palmitoyltransferase I in INS1E cells: effects on cell metabolism and insulin secretion.
Topics: Adenosine Triphosphate; Adenoviridae; Animals; Blotting, Western; Carnitine O-Palmitoyltransferase; Cell Line; Cells, Cultured; DNA, Complementary; Enzyme Inhibitors; Epoxy Compounds; Fatty Acids; Glucose; Hypoglycemic Agents; Insulin; Islets of Langerhans; Liver; Mitochondria; Oxygen; Palmitic Acid; Potassium Chloride; Protein Isoforms; Rats; Triglycerides; Up-Regulation | 2002 |
Impact of mitochondrial beta-oxidation in fatty acid-mediated inhibition of glioma cell proliferation.
Topics: Animals; Apoptosis; Carnitine; Cell Division; Epoxy Compounds; Fatty Acids; Gas Chromatography-Mass Spectrometry; Glioma; Glutathione; Humans; Mitochondria; Oxidation-Reduction; Palmitic Acid; Rats; Sphingolipids; Sulfides; Tumor Cells, Cultured | 2003 |
Protein acylation in the inhibition of insulin secretion by norepinephrine, somatostatin, galanin, and PGE2.
Topics: Acylation; Acyltransferases; Animals; Cerulenin; Cyclic AMP; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Epoxy Compounds; Fatty Acids, Unsaturated; Galanin; GTP-Binding Proteins; Hypoglycemic Agents; Insulin; Insulin Secretion; Lipid Metabolism; Male; Norepinephrine; Oxidation-Reduction; Palmitates; Palmitic Acid; Proteins; Rats; Rats, Sprague-Dawley; Somatostatin | 2003 |
Novel effect of C75 on carnitine palmitoyltransferase I activity and palmitate oxidation.
Topics: 4-Butyrolactone; Acyl Coenzyme A; Animals; Carnitine O-Palmitoyltransferase; Cells, Cultured; Coenzyme A Ligases; Epoxy Compounds; Humans; Kinetics; Male; Mice; Mice, Inbred C57BL; Mitochondria, Liver; Mitochondria, Muscle; Oxidation-Reduction; Palmitic Acid; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2006 |
Fatty acid-induced effect on glucagon secretion is mediated via fatty acid oxidation.
Topics: Animals; Carnitine O-Palmitoyltransferase; DNA; Epoxy Compounds; Fatty Acids; Gene Expression Regulation; Glucagon; Glucagon-Secreting Cells; Mice; Oleic Acid; Oxidation-Reduction; Palmitic Acid; Triglycerides; Tumor Cells, Cultured | 2007 |
Saturated fatty acids inhibit hepatic insulin action by modulating insulin receptor expression and post-receptor signalling.
Topics: Aminoimidazole Carboxamide; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Enzyme Activation; Enzyme Inhibitors; Epoxy Compounds; Extracellular Signal-Regulated MAP Kinases; Fatty Acids; Fatty Acids, Nonesterified; Forkhead Transcription Factors; Glycogen Synthase Kinase 3; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Liver; Liver Neoplasms; Mice; Mice, Knockout; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Palmitic Acid; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Receptor, Insulin; Ribonucleotides; Signal Transduction; Triazenes | 2008 |
AMPK-independent pathways regulate skeletal muscle fatty acid oxidation.
Topics: Acetyl-CoA Carboxylase; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Carnitine O-Palmitoyltransferase; Enzyme Inhibitors; Epoxy Compounds; Fatty Acids; Immunoblotting; Malonyl Coenzyme A; Mice; Mice, Inbred Strains; Mice, Transgenic; Motor Activity; Muscle Contraction; Muscle, Skeletal; Oxidation-Reduction; Palmitic Acid; Phosphorylation; Ribonucleotides; Signal Transduction; Sterol Esterase | 2008 |
Influence of mitochondrial β-oxidation on early pea seedling development.
Topics: Carbon Radioisotopes; Carnitine; Carnitine O-Palmitoyltransferase; Chlorophyll; Cotyledon; Epoxy Compounds; Lipid Metabolism; Microscopy, Electron, Transmission; Mitochondria; Oxidation-Reduction; Palmitic Acid; Peroxisomes; Pisum sativum; Seedlings; Spectrometry, Mass, Electrospray Ionization; Starch | 2009 |
Fatty acid oxidation and meiotic resumption in mouse oocytes.
Topics: 4-Butyrolactone; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Cerulenin; Cumulus Cells; Epoxy Compounds; Fatty Acids; Female; Malonyl Coenzyme A; Meiosis; Mice; Mice, Inbred C57BL; Oocytes; Oxidation-Reduction; Palmitic Acid; Ribonucleotides | 2009 |
Toxicity generated through inhibition of pyruvate carboxylase and carnitine palmitoyl transferase-1 is similar to high glucose/palmitate-induced glucolipotoxicity in INS-1 beta cells.
Topics: Animals; Apoptosis; Calcium; Carnitine O-Palmitoyltransferase; Cell Line, Tumor; Citric Acid Cycle; Endoplasmic Reticulum Stress; Epoxy Compounds; Gene Expression Regulation; Glucose; Insulin-Secreting Cells; Male; MAP Kinase Kinase 4; Mitochondria; Palmitic Acid; Phenylacetates; Primary Cell Culture; Proto-Oncogene Proteins c-akt; Pyruvate Carboxylase; Rats; RNA, Small Interfering; Signal Transduction | 2014 |
Fatty acid metabolism during maturation affects glucose uptake and is essential to oocyte competence.
Topics: Animals; Biological Transport; Carnitine; Carnitine O-Palmitoyltransferase; Cells, Cultured; Coculture Techniques; Cumulus Cells; Energy Metabolism; Enzyme Inhibitors; Epoxy Compounds; Female; Fertilization in Vitro; Gene Expression Regulation, Developmental; Glucose; In Vitro Oocyte Maturation Techniques; Mice; Oocytes; Oxidation-Reduction; Palmitic Acid; Time Factors; Zygote | 2014 |
Molecular Mechanism of Palmitic Acid on Myocardial Contractility in Hypertensive Rats and Its Relationship with Neural Nitric Oxide Synthase Protein in Cardiomyocytes.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Carnitine O-Palmitoyltransferase; Epoxy Compounds; Hypertension; Male; Muscle Contraction; Myocytes, Cardiac; Nitric Oxide Synthase Type I; Palmitic Acid; Rats, Inbred SHR; Rats, Sprague-Dawley | 2021 |