etomoxir has been researched along with oleic acid in 14 studies
| Studies (etomoxir) | Trials (etomoxir) | Recent Studies (post-2010) (etomoxir) | Studies (oleic acid) | Trials (oleic acid) | Recent Studies (post-2010) (oleic acid) |
|---|---|---|---|---|---|
| 260 | 8 | 93 | 8,768 | 248 | 3,051 |
| Protein | Taxonomy | etomoxir (IC50) | oleic acid (IC50) |
|---|---|---|---|
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | 6.2 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (28.57) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 5 (35.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Björntorp, P; Lönnroth, P; Smith, U; Svedberg, J | 2 |
| Grill, VE; Zhou, YP | 1 |
| Brandt, JM; Djouadi, F; Kelly, DP | 1 |
| Cnop, M; Eizirik, DL; Hannaert, JC; Hoorens, A; Pipeleers, DG | 1 |
| Biden, TJ; Cazzolli, R; Craig, DL; Schmitz-Peiffer, C | 1 |
| Mishra, R; Simonson, MS | 1 |
| Hermansen, K; Hong, J; Jeppesen, PB; Nordentoft, I | 1 |
| Boysen, G; Brooks, NL; Carling, D; Combs, TP; Flurkey, K; Harrison, DE; Jeong, YC; Khodush, VR; Klebanov, S; Kupper, LL; Patel, KB; Perfetti, MT; Raetzsch, CF; Swenberg, JA; Trent, CM | 1 |
| Cruz-Garcia, L; Gutiérrez, J; Navarro, I; Sánchez-Gurmaches, J | 1 |
| Czaja, MJ; Fiel, MI; Friedman, SL; Ghiassi-Nejad, Z; Gordon, R; Hernández-Gea, V; Rozenfeld, R; Yue, Z | 1 |
| Huang, G; Li, J; Liu, J; Miao, P; Song, S; Sun, X; Zhang, T; Zhao, L; Zhao, S; Zhao, X; Zhou, X | 1 |
| Bakhteeva, VT; Fedorova, EV; Fok, EM; Lavrova, EA; Parnova, RG | 1 |
14 other study(ies) available for etomoxir and oleic acid
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Effect of free fatty acids on insulin receptor binding and tyrosine kinase activity in hepatocytes isolated from lean and obese rats.
Topics: Animals; Cells, Cultured; Epoxy Compounds; Fatty Acids, Nonesterified; Hypoglycemic Agents; Insulin; Kinetics; Liver; Male; Obesity; Oleic Acid; Oleic Acids; Protein-Tyrosine Kinases; Rats; Rats, Inbred Strains; Receptor, Insulin; Reference Values | 1992 |
Prevention of inhibitory effect of free fatty acids on insulin binding and action in isolated rat hepatocytes by etomoxir.
Topics: Aminoisobutyric Acids; Animals; Biological Transport; Cells, Cultured; Dose-Response Relationship, Drug; Epoxy Compounds; Hypoglycemic Agents; Insulin; Kinetics; Liver; Male; Oleic Acid; Oleic Acids; Rats; Rats, Inbred Strains; Receptor, Insulin | 1991 |
Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle.
Topics: Animals; Caprylates; Carnitine O-Palmitoyltransferase; Cells, Cultured; Epoxy Compounds; Ethanol; Fatty Acids, Nonesterified; Glucose; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Kinetics; Male; Oleic Acid; Oleic Acids; Palmitic Acid; Palmitic Acids; Proinsulin; Protein Biosynthesis; Proteins; Rats; Rats, Sprague-Dawley; Time Factors | 1994 |
Fatty acids activate transcription of the muscle carnitine palmitoyltransferase I gene in cardiac myocytes via the peroxisome proliferator-activated receptor alpha.
Topics: Animals; Animals, Newborn; Base Sequence; Carnitine O-Palmitoyltransferase; Cells, Cultured; Cloning, Molecular; Epoxy Compounds; Fatty Acids, Nonesterified; Genes, Reporter; Humans; Luciferases; Mice; Mice, Knockout; Muscle, Skeletal; Myocardium; Oleic Acid; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; Repetitive Sequences, Nucleic Acid; RNA, Messenger; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection | 1998 |
Inverse relationship between cytotoxicity of free fatty acids in pancreatic islet cells and cellular triglyceride accumulation.
Topics: Animals; Apoptosis; Carnitine O-Palmitoyltransferase; Cell Survival; Cells, Cultured; Cytoplasm; Enzyme Inhibitors; Epoxy Compounds; Fatty Acids, Nonesterified; Islets of Langerhans; Kinetics; Male; Oleic Acid; Palmitic Acid; Palmitic Acids; Rats; Rats, Wistar; Time Factors; Triglycerides | 2001 |
Inhibition of glycogen synthesis by fatty acid in C(2)C(12) muscle cells is independent of PKC-alpha, -epsilon, and -theta.
Topics: Animals; Cell Line; Enzyme Activation; Enzyme Inhibitors; Epoxy Compounds; Fatty Acids, Unsaturated; Gene Expression; Glycogen; Immunoblotting; Insulin; Isoenzymes; Kinetics; Lipid Metabolism; Mice; Mitochondria; Muscles; Mutation; Oleic Acid; Oxidation-Reduction; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; Protein Kinase C-theta; Transfection | 2002 |
Saturated free fatty acids and apoptosis in microvascular mesangial cells: palmitate activates pro-apoptotic signaling involving caspase 9 and mitochondrial release of endonuclease G.
Topics: Apoptosis; Blotting, Western; Caspase 9; Caspases; Cells, Cultured; Cytochromes c; Endodeoxyribonucleases; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Epoxy Compounds; Humans; Linoleic Acid; Mesangial Cells; Mitochondria; Oleic Acid; Palmitates; Signal Transduction; Stearates | 2005 |
Fatty acid-induced effect on glucagon secretion is mediated via fatty acid oxidation.
Topics: Animals; Carnitine O-Palmitoyltransferase; DNA; Epoxy Compounds; Fatty Acids; Gene Expression Regulation; Glucagon; Glucagon-Secreting Cells; Mice; Oleic Acid; Oxidation-Reduction; Palmitic Acid; Triglycerides; Tumor Cells, Cultured | 2007 |
Low utilization of circulating glucose after food withdrawal in Snell dwarf mice.
Topics: Animals; Aorta; Body Composition; Cattle; Coumaric Acids; Epoxy Compounds; Fatty Acids; Female; Food Deprivation; Glucose; Glycogenolysis; Mice; Mice, Inbred C57BL; Mutation; Oleic Acid; Oxygen; Reactive Oxygen Species; Triglycerides | 2007 |
Endocrine control of oleic acid and glucose metabolism in rainbow trout (Oncorhynchus mykiss) muscle cells in culture.
Topics: Animals; Carbon Dioxide; Carnitine O-Palmitoyltransferase; Catecholamines; Cells, Cultured; Energy Metabolism; Epoxy Compounds; Glucose; Glycogen; Hypoglycemic Agents; Insulin; Insulin-Like Growth Factor I; Intracellular Signaling Peptides and Proteins; Muscle Fibers, Skeletal; Oleic Acid; Oncorhynchus mykiss; Oxidation-Reduction; PPAR gamma; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Rosiglitazone; Sirolimus; Thiazolidinediones; TOR Serine-Threonine Kinases; Triglycerides | 2010 |
Autophagy releases lipid that promotes fibrogenesis by activated hepatic stellate cells in mice and in human tissues.
Topics: Adenine; Adenosine Triphosphate; Animals; Autophagy; Autophagy-Related Protein 5; Autophagy-Related Protein 7; Carbon Tetrachloride; Cell Line; Energy Metabolism; Epoxy Compounds; Fibroblasts; Hepatic Stellate Cells; Humans; Idiopathic Pulmonary Fibrosis; Kidney; Lipid Metabolism; Liver; Liver Cirrhosis, Experimental; Lung; Mice; Mice, Inbred C57BL; Mice, Knockout; Microtubule-Associated Proteins; Oleic Acid; RNA Interference; Thioacetamide | 2012 |
Inhibition of lipolysis by mercaptoacetate and etomoxir specifically sensitize drug-resistant lung adenocarcinoma cell to paclitaxel.
Topics: Adenocarcinoma; Antineoplastic Agents; Carbon Dioxide; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Enzyme Inhibitors; Epoxy Compounds; Glucose; Glycolysis; Humans; Lipolysis; Lung Neoplasms; Oleic Acid; Oxidative Phosphorylation; Paclitaxel; Thioglycolates | 2013 |
[Deposition of exogenous and endogenously generated unsaturated fatty acids in lipid droplets triacylglycerol as a mechanism of its sequestration in epithelial cells].
Topics: Animals; Arachidonic Acid; Biological Transport; Carnitine O-Palmitoyltransferase; Cholesterol Esters; Cyclooxygenase 1; Cyclooxygenase 2; Diclofenac; Dinoprostone; Enzyme Inhibitors; Epithelial Cells; Epoxy Compounds; Lipid Droplets; Lipid Metabolism; Oleic Acid; Primary Cell Culture; Rana temporaria; Triglycerides; Tritium; Urinary Bladder; Urothelium | 2014 |