Page last updated: 2024-09-03

etomoxir and malonyl coenzyme a

etomoxir has been researched along with malonyl coenzyme a in 15 studies

Compound Research Comparison

Studies
(etomoxir)
Trials
(etomoxir)
Recent Studies (post-2010)
(etomoxir)
Studies
(malonyl coenzyme a)
Trials
(malonyl coenzyme a)
Recent Studies (post-2010) (malonyl coenzyme a)
2608931,1697278

Protein Interaction Comparison

ProteinTaxonomyetomoxir (IC50)malonyl coenzyme a (IC50)
Carnitine O-palmitoyltransferase 1, muscle isoformRattus norvegicus (Norway rat)1.2

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (46.67)18.2507
2000's6 (40.00)29.6817
2010's2 (13.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Murthy, MS; Pande, SV1
Chen, S; Foster, DW; McGarry, JD; Ogawa, A; Ohneda, M; Unger, RH1
Bieber, LL; Gage, D; Kerner, J; Zaluzec, E1
Alam, N; Saggerson, ED1
Brown, NF; Foster, DW; McGarry, JD; Swanson, ST1
Adams, SH; Brown, NF; Esser, V; Foster, DW; Ing, NH; Johnson, L; McGarry, JD1
Elliott, KR; Krauss, S; New, KJ; Quant, PA1
Asins, G; Bach, M; Caudevilla, C; Codony, C; Hegardt, FG; Morillas, M; Serra, D1
Kuhajda, FP; Pinn, ML; Thupari, JN1
Kuhajda, FP; Landree, LE; Ronnett, GV; Thupari, JN1
Cortright, RN; Dudek, RW; Evans, JR; Lust, RM; Manning, SM; Noland, RC; Whitfield, BR; Woodlief, TL1
Chen, ZP; Dzamko, N; Jørgensen, SB; Kemp, BE; Lynch, GS; Macaulay, SL; Michell, BJ; Oakhill, JS; Ryall, JG; Schertzer, JD; Steel, R; Steinberg, GR; Watt, MJ; Wee, S1
Downs, SM; Klinger, J; Mosey, JL1
Gao, S; Hegardt, FG; Keung, W; Lopaschuk, GD; Serra, D1
Downs, SM; Valsangkar, D1

Other Studies

15 other study(ies) available for etomoxir and malonyl coenzyme a

ArticleYear
Characterization of a solubilized malonyl-CoA-sensitive carnitine palmitoyltransferase from the mitochondrial outer membrane as a protein distinct from the malonyl-CoA-insensitive carnitine palmitoyltransferase of the inner membrane.
    The Biochemical journal, 1990, Jun-15, Volume: 268, Issue:3

    Topics: Acyl Coenzyme A; Acyltransferases; Animals; Azetidines; Carnitine O-Palmitoyltransferase; Chromatography, High Pressure Liquid; Epoxy Compounds; Intracellular Membranes; Malonyl Coenzyme A; Membrane Proteins; Mitochondria, Liver; Palmitoyl Coenzyme A; Rats; Solubility

1990
More direct evidence for a malonyl-CoA-carnitine palmitoyltransferase I interaction as a key event in pancreatic beta-cell signaling.
    Diabetes, 1994, Volume: 43, Issue:7

    Topics: Animals; ATP Citrate (pro-S)-Lyase; Carnitine O-Palmitoyltransferase; Citrates; Epoxy Compounds; Glucose; Hypoglycemic Agents; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Malonyl Coenzyme A; Palmitates; Palmitic Acid; Palmitic Acids; Rats; Rats, Sprague-Dawley; Signal Transduction; Stearic Acids; Time Factors

1994
Characterization of the malonyl-CoA-sensitive carnitine palmitoyltransferase (CPTo) of a rat heart mitochondrial particle. Evidence that the catalytic unit is CPTi.
    The Journal of biological chemistry, 1994, Mar-18, Volume: 269, Issue:11

    Topics: Amino Acid Sequence; Animals; Blotting, Western; Carnitine O-Palmitoyltransferase; Cell Fractionation; Chromatography, Affinity; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Epoxy Compounds; Freezing; Kinetics; Macromolecular Substances; Malonyl Coenzyme A; Mass Spectrometry; Mitochondria, Heart; Molecular Weight; Peptide Fragments; Peptide Mapping; Rats; Submitochondrial Particles; Ultracentrifugation

1994
Malonyl-CoA and the regulation of fatty acid oxidation in soleus muscle.
    The Biochemical journal, 1998, Aug-15, Volume: 334 ( Pt 1)

    Topics: Acyl Coenzyme A; Animals; ATP Citrate (pro-S)-Lyase; Carboxy-Lyases; Carnitine O-Palmitoyltransferase; Enzyme Inhibitors; Epoxy Compounds; Fatty Acid Synthases; Glucose; In Vitro Techniques; Kinetics; Malate Dehydrogenase; Male; Malonyl Coenzyme A; Models, Biological; Muscle, Skeletal; Oxidation-Reduction; Palmitic Acid; Rats; Rats, Sprague-Dawley; Regression Analysis

1998
Roles of the N- and C-terminal domains of carnitine palmitoyltransferase I isoforms in malonyl-CoA sensitivity of the enzymes: insights from expression of chimaeric proteins and mutation of conserved histidine residues.
    The Biochemical journal, 1998, Nov-01, Volume: 335 ( Pt 3)

    Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Carnitine O-Palmitoyltransferase; Conserved Sequence; COS Cells; Epoxy Compounds; Histidine; Isoenzymes; Kinetics; Malonyl Coenzyme A; Mutagenesis, Site-Directed; Peptide Fragments; Point Mutation; Rats; Recombinant Fusion Proteins; Transfection

1998
Expression and possible role of muscle-type carnitine palmitoyltransferase I during sperm development in the rat.
    Biology of reproduction, 1998, Volume: 59, Issue:6

    Topics: Animals; Blotting, Northern; Carnitine; Carnitine O-Palmitoyltransferase; Enzyme Inhibitors; Epoxy Compounds; Gene Expression; In Situ Hybridization; Isoenzymes; Male; Malonyl Coenzyme A; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spermatogenesis; Spermatozoa; Testis

1998
Comparisons of flux control exerted by mitochondrial outer-membrane carnitine palmitoyltransferase over ketogenesis in hepatocytes and mitochondria isolated from suckling or adult rats.
    European journal of biochemistry, 1999, Volume: 259, Issue:3

    Topics: Animals; Animals, Suckling; Carbon Dioxide; Carnitine; Carnitine O-Palmitoyltransferase; Cells, Cultured; Energy Metabolism; Enzyme Inhibitors; Epoxy Compounds; Ketone Bodies; Liver; Malonyl Coenzyme A; Membrane Proteins; Mitochondria, Liver; Palmitic Acid; Palmitoyl Coenzyme A; Palmitoylcarnitine; Rats; Rats, Wistar

1999
Post-transcriptional regulation of rat carnitine octanoyltransferase.
    Biochemical Society transactions, 2001, Volume: 29, Issue:Pt 2

    Topics: Acyl Coenzyme A; Animals; Base Sequence; Carnitine Acyltransferases; Enzyme Inhibitors; Epoxy Compounds; Exons; Female; Male; Malonyl Coenzyme A; Mutation; Rats; RNA, Messenger; Trans-Splicing

2001
Fatty acid synthase inhibition in human breast cancer cells leads to malonyl-CoA-induced inhibition of fatty acid oxidation and cytotoxicity.
    Biochemical and biophysical research communications, 2001, Jul-13, Volume: 285, Issue:2

    Topics: Acetyl-CoA Carboxylase; Apoptosis; Breast Neoplasms; Carnitine O-Palmitoyltransferase; Cell Survival; Cerulenin; Enzyme Inhibitors; Epoxy Compounds; Fatty Acid Synthases; Fatty Acids; Female; Furans; Humans; Hypolipidemic Agents; Kinetics; Malonyl Coenzyme A; Models, Biological; Oxidation-Reduction; Tumor Cells, Cultured

2001
C75 increases peripheral energy utilization and fatty acid oxidation in diet-induced obesity.
    Proceedings of the National Academy of Sciences of the United States of America, 2002, Jul-09, Volume: 99, Issue:14

    Topics: 3T3 Cells; 4-Butyrolactone; Adenosine Triphosphate; Adipocytes; Animals; Carnitine O-Palmitoyltransferase; Diet; Energy Metabolism; Enzyme Inhibitors; Epoxy Compounds; Fatty Acid Synthases; Fatty Acids; Humans; Male; Malonyl Coenzyme A; Mice; Mice, Inbred C57BL; Obesity; Oxidation-Reduction; Tumor Cells, Cultured; Weight Loss

2002
Peroxisomal-mitochondrial oxidation in a rodent model of obesity-associated insulin resistance.
    American journal of physiology. Endocrinology and metabolism, 2007, Volume: 293, Issue:4

    Topics: Animals; Disease Models, Animal; Epoxy Compounds; Glucose Tolerance Test; Hypoglycemic Agents; Insulin Resistance; Lipids; Liver; Male; Malonyl Coenzyme A; Mitochondria, Liver; Mitochondria, Muscle; Obesity; Oxidation-Reduction; Peroxisomes; Rats; Rats, Sprague-Dawley; Rats, Zucker

2007
AMPK-independent pathways regulate skeletal muscle fatty acid oxidation.
    The Journal of physiology, 2008, Dec-01, Volume: 586, Issue:23

    Topics: Acetyl-CoA Carboxylase; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Carnitine O-Palmitoyltransferase; Enzyme Inhibitors; Epoxy Compounds; Fatty Acids; Immunoblotting; Malonyl Coenzyme A; Mice; Mice, Inbred Strains; Mice, Transgenic; Motor Activity; Muscle Contraction; Muscle, Skeletal; Oxidation-Reduction; Palmitic Acid; Phosphorylation; Ribonucleotides; Signal Transduction; Sterol Esterase

2008
Fatty acid oxidation and meiotic resumption in mouse oocytes.
    Molecular reproduction and development, 2009, Volume: 76, Issue:9

    Topics: 4-Butyrolactone; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Cerulenin; Cumulus Cells; Epoxy Compounds; Fatty Acids; Female; Malonyl Coenzyme A; Meiosis; Mice; Mice, Inbred C57BL; Oocytes; Oxidation-Reduction; Palmitic Acid; Ribonucleotides

2009
Important role of ventromedial hypothalamic carnitine palmitoyltransferase-1a in the control of food intake.
    American journal of physiology. Endocrinology and metabolism, 2013, Aug-01, Volume: 305, Issue:3

    Topics: Acyl Coenzyme A; Animals; Appetite Depressants; Arcuate Nucleus of Hypothalamus; Blotting, Western; Body Weight; Carnitine; Carnitine O-Palmitoyltransferase; Dependovirus; Eating; Enzyme Activation; Epoxy Compounds; Fasting; Genetic Vectors; Hypoglycemic Agents; Injections, Intraventricular; Male; Malonyl Coenzyme A; Rats; Rats, Sprague-Dawley; Ventromedial Hypothalamic Nucleus

2013
A requirement for fatty acid oxidation in the hormone-induced meiotic maturation of mouse oocytes.
    Biology of reproduction, 2013, Volume: 89, Issue:2

    Topics: Acyl Coenzyme A; Aminoimidazole Carboxamide; Aminophenols; AMP-Activated Protein Kinases; Amphiregulin; Animals; Cumulus Cells; EGF Family of Proteins; Epidermal Growth Factor; Epoxy Compounds; Fatty Acids; Female; Follicle Stimulating Hormone; Glycoproteins; Hydrazones; Intercellular Signaling Peptides and Proteins; Malonyl Coenzyme A; Meiosis; Mice; Oocytes; Ovarian Follicle; Oxidation-Reduction; Ribonucleotides; Thioglycolates

2013