Page last updated: 2024-09-03

etomoxir and lovastatin

etomoxir has been researched along with lovastatin in 3 studies

Compound Research Comparison

Studies
(etomoxir)
Trials
(etomoxir)
Recent Studies (post-2010)
(etomoxir)
Studies
(lovastatin)
Trials
(lovastatin)
Recent Studies (post-2010) (lovastatin)
2608934,828698873

Protein Interaction Comparison

ProteinTaxonomyetomoxir (IC50)lovastatin (IC50)
Chain A, Antigen Cd11a (p180)Homo sapiens (human)2.4
3-hydroxy-3-methylglutaryl-coenzyme A reductaseHomo sapiens (human)0.0261
Integrin beta-2Homo sapiens (human)3.09
Intercellular adhesion molecule 1Homo sapiens (human)3.78
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)8.753
ATP-dependent translocase ABCB1Homo sapiens (human)10
Neutrophil elastaseHomo sapiens (human)0.027
Insulin receptor Rattus norvegicus (Norway rat)0.02
Integrin alpha-LHomo sapiens (human)3.09
Sodium-dependent noradrenaline transporter Homo sapiens (human)8.753
Prostaglandin G/H synthase 2Homo sapiens (human)0.02
3-hydroxy-3-methylglutaryl-coenzyme A reductase Rattus norvegicus (Norway rat)0.0529

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y1
Dolovcak, S; Emmett, D; Esser, V; Fitz, JG; Kilic, G; Parameswara, V; Puljak, L; Waldrop, SL1

Other Studies

3 other study(ies) available for etomoxir and lovastatin

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
    Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index

2014
Evidence for AMPK-dependent regulation of exocytosis of lipoproteins in a model liver cell line.
    Experimental cell research, 2008, Jun-10, Volume: 314, Issue:10

    Topics: Aminoimidazole Carboxamide; Amiodarone; AMP-Activated Protein Kinases; Animals; Apolipoproteins B; Cell Line; Enzyme Inhibitors; Epoxy Compounds; Exocytosis; Fatty Acids; Hepatocytes; Humans; Hypoglycemic Agents; Lipid Metabolism; Lovastatin; Metformin; Multienzyme Complexes; Oxidation-Reduction; Patch-Clamp Techniques; Protein Serine-Threonine Kinases; Rats; Ribonucleotides; Sterol Regulatory Element Binding Protein 1; Triglycerides

2008