Compounds > etomoxir
Page last updated: 2024-09-03

etomoxir and diclofenac

etomoxir has been researched along with diclofenac in 3 studies

Compound Research Comparison

Studies
(etomoxir)		Trials
(etomoxir)		Recent Studies (post-2010)
(etomoxir)		Studies
(diclofenac)		Trials
(diclofenac)		Recent Studies (post-2010) (diclofenac)
2608938,8741,8743,616

Protein Interaction Comparison

ProteinTaxonomyetomoxir (IC50)diclofenac (IC50)
Aldo-keto reductase family 1 member B10Homo sapiens (human)1.9
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.003
Prostaglandin G/H synthase 1Ovis aries (sheep)1.3376
Interleukin-8Homo sapiens (human)0.008
Prostaglandin G/H synthase 1Homo sapiens (human)0.0415
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)0.5
C-X-C chemokine receptor type 1Homo sapiens (human)0.012
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)0.5
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.5
Prostaglandin G/H synthase 2Homo sapiens (human)0.4165
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.5
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.5
Prostaglandin G/H synthase 2Ovis aries (sheep)1.6867
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.0502
Solute carrier family 22 member 6Homo sapiens (human)4
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.5
P2Y purinoceptor 12Rattus norvegicus (Norway rat)0.02

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y1
Bakhteeva, VT; Fedorova, EV; Fok, EM; Lavrova, EA; Parnova, RG1

Other Studies

3 other study(ies) available for etomoxir and diclofenac

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
    Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index

2014
[Deposition of exogenous and endogenously generated unsaturated fatty acids in lipid droplets triacylglycerol as a mechanism of its sequestration in epithelial cells].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2014, Volume: 100, Issue:8

    Topics: Animals; Arachidonic Acid; Biological Transport; Carnitine O-Palmitoyltransferase; Cholesterol Esters; Cyclooxygenase 1; Cyclooxygenase 2; Diclofenac; Dinoprostone; Enzyme Inhibitors; Epithelial Cells; Epoxy Compounds; Lipid Droplets; Lipid Metabolism; Oleic Acid; Primary Cell Culture; Rana temporaria; Triglycerides; Tritium; Urinary Bladder; Urothelium

2014