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ethylphenylhydantoin and phenobarbital

ethylphenylhydantoin has been researched along with phenobarbital in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's2 (40.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Devor, DE; Diwan, BA; Dragnev, KH; Jones, CR; Lubet, RA; Miller, MS; Nims, RW; Rice, JM; Ward, JM1
Diwan, BA; Hu, H; Lubet, RA; Nims, RW; Rice, JM; Ward, JM1
Roeda, D; Westera, G1
Diwan, BA; Lubet, RA; Mellini, DW; Nims, RW; Thomas, PE; Utermahlen, WE1
Jones, JP; Kneller, MB; Rettie, AE; Rock, DA; Suzuki, H; Trager, WF1

Other Studies

5 other study(ies) available for ethylphenylhydantoin and phenobarbital

ArticleYear
A markedly diminished pleiotropic response to phenobarbital and structurally-related xenobiotics in Zucker rats in comparison with F344/NCr or DA rats.
    Biochemical pharmacology, 1992, Mar-03, Volume: 43, Issue:5

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Barbital; Base Sequence; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Induction; Epoxide Hydrolases; Female; Glutathione Transferase; Liver; Mephenytoin; Molecular Sequence Data; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred F344; Rats, Zucker; Steroid Hydroxylases; Xenobiotics

1992
P-450 enzyme induction by 5-ethyl-5-phenylhydantoin and 5,5-diethylhydantoin, analogues of barbiturate tumor promoters phenobarbital and barbital, and promotion of liver and thyroid carcinogenesis initiated by N-nitrosodiethylamine in rats.
    Cancer research, 1988, May-01, Volume: 48, Issue:9

    Topics: Animals; Barbital; Barbiturates; Body Weight; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Enzyme Induction; Hydantoins; Liver; Liver Neoplasms, Experimental; Male; Mephenytoin; Organ Size; Phenobarbital; Rats; Rats, Inbred F344; Thyroid Neoplasms

1988
The synthesis of some 11C-labelled antiepileptic drugs with potential utility as radiopharmaceuticals: hydantoins and barbiturates.
    The International journal of applied radiation and isotopes, 1981, Volume: 32, Issue:11

    Topics: Anticonvulsants; Barbital; Barbiturates; Carbon Radioisotopes; Hydantoins; Isotope Labeling; Mephenytoin; Phenobarbital; Phenytoin

1981
Hepatic cytochrome P450 2B induction by ethyl/phenyl-substituted congeners of phenobarbital in the B6C3F1 mouse.
    Journal of biochemical toxicology, 1994, Volume: 9, Issue:5

    Topics: Animals; Anticonvulsants; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Induction; Liver; Male; Mephenytoin; Mice; Phenobarbital; Phenols; Rats; Rats, Inbred F344; Species Specificity; Structure-Activity Relationship

1994
Active-site characteristics of CYP2C19 and CYP2C9 probed with hydantoin and barbiturate inhibitors.
    Archives of biochemistry and biophysics, 2004, Sep-01, Volume: 429, Issue:1

    Topics: Aryl Hydrocarbon Hydroxylases; Barbiturates; Binding Sites; Computer Simulation; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Drug Design; Enzyme Activation; Hydantoins; Mephenytoin; Mixed Function Oxygenases; Models, Chemical; Models, Molecular; Phenobarbital; Phenytoin; Protein Binding

2004