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ethylphenylhydantoin and hydantoins

ethylphenylhydantoin has been researched along with hydantoins in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199016 (88.89)18.7374
1990's1 (5.56)18.2507
2000's1 (5.56)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
MacMillan, SF; Raisys, VA; Zebelman, AM1
Bircher, J; Küpfer, A; Preisig, R1
Pezeshk, A; Pezeshk, V1
Diwan, BA; Hu, H; Lubet, RA; Nims, RW; Rice, JM; Ward, JM1
Alpin, RS; Day, PA; Hall, IH; Maguire, JH; Wong, OT1
Inaba, T1
Inaba, T; Jurima, M; Kalow, W1
Desai, BT; Kupferberg, HJ; Newmark, ME; Penry, JK; Porter, RJ; Theodore, WH; Yonekawa, WD1
Küpfer, A; Preisig, R1
Branch, RA; McAllister, CB; Sweetman, BJ; Wedlund, PJ; Wilkinson, GR1
Branch, RA; Küpfer, A; Patwardhan, R; Preisig, R; Schenker, S; Ward, S1
Harbison, RD; Küpfer, A; Lawson, JA; Wells, PG1
Roeda, D; Westera, G1
BUTLER, TC2
BUTLER, TC; WADDELL, WJ1
CRAVIOTTO, C1
Jones, JP; Kneller, MB; Rettie, AE; Rock, DA; Suzuki, H; Trager, WF1

Reviews

1 review(s) available for ethylphenylhydantoin and hydantoins

ArticleYear
Genetic polymorphism of mephenytoin metabolism.
    Progress in clinical and biological research, 1986, Volume: 214

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Chemical Phenomena; Chemistry; China; Cytochrome P-450 CYP2C19; Debrisoquin; Dogs; Ethnicity; Humans; Hydantoins; Hydroxylation; Japan; Kinetics; Liver; Mephenytoin; Mephobarbital; Mice; Mixed Function Oxygenases; Ontario; Phenotype; Polymorphism, Genetic; Sparteine; Tennessee; White People

1986

Other Studies

17 other study(ies) available for ethylphenylhydantoin and hydantoins

ArticleYear
Gas-chromatographic determination of mephenytoin and desmethylmephenytoin, after off-column alkylation.
    Clinical chemistry, 1979, Volume: 25, Issue:1

    Topics: Alkylation; Chromatography, Gas; Humans; Hydantoins; Mephenytoin

1979
Stereoselective metabolism, pharmacokinetics and biliary elimination of phenylethylhydantoin (Nirvanol) in the dog.
    The Journal of pharmacology and experimental therapeutics, 1977, Volume: 203, Issue:3

    Topics: Animals; Bile; Chromatography, Gas; Dogs; Female; Hydantoins; Kinetics; Mephenytoin; Stereoisomerism

1977
Drug-metal interactions: spectroscopic studies of copper hydantoin complexes.
    Journal of inorganic biochemistry, 1991, Volume: 42, Issue:4

    Topics: Copper; Crystallization; Electron Spin Resonance Spectroscopy; Hydantoins; Mephenytoin; Molecular Structure; Phenytoin; Pyridines; Spectrophotometry, Infrared

1991
P-450 enzyme induction by 5-ethyl-5-phenylhydantoin and 5,5-diethylhydantoin, analogues of barbiturate tumor promoters phenobarbital and barbital, and promotion of liver and thyroid carcinogenesis initiated by N-nitrosodiethylamine in rats.
    Cancer research, 1988, May-01, Volume: 48, Issue:9

    Topics: Animals; Barbital; Barbiturates; Body Weight; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Enzyme Induction; Hydantoins; Liver; Liver Neoplasms, Experimental; Male; Mephenytoin; Organ Size; Phenobarbital; Rats; Rats, Inbred F344; Thyroid Neoplasms

1988
A comparison of the S(+) and R(-) enantiomers of 5-ethyl-5-phenylhydantoin as hypolipidemic agents in rodents.
    Biomedica biochimica acta, 1987, Volume: 46, Issue:7

    Topics: Administration, Oral; Animals; Cholesterol; Feces; Hydantoins; Hypolipidemic Agents; Injections, Intraperitoneal; Intestine, Small; Isomerism; Lipid Metabolism; Lipoproteins; Liver; Male; Mephenytoin; Mice; Rats; Rats, Inbred Strains; Reference Values; Structure-Activity Relationship; Triglycerides

1987
Family studies of mephenytoin hydroxylation deficiency.
    American journal of human genetics, 1986, Volume: 38, Issue:5

    Topics: Adolescent; Adult; Female; Genes, Recessive; Humans; Hydantoins; Hydroxylation; Male; Mephenytoin; Middle Aged; Pedigree; Phenotype

1986
Disposition of mephenytoin and its metabolite, nirvanol, in epileptic patients.
    Neurology, 1984, Volume: 34, Issue:8

    Topics: Adolescent; Adult; Epilepsies, Partial; Female; Humans; Hydantoins; Male; Mephenytoin

1984
Pharmacogenetics of mephenytoin: a new drug hydroxylation polymorphism in man.
    European journal of clinical pharmacology, 1984, Volume: 26, Issue:6

    Topics: Adult; Debrisoquin; Female; Humans; Hydantoins; Hydroxylation; Male; Mephenytoin; Phenotype; Polymorphism, Genetic

1984
Direct enantiomeric resolution of mephenytoin and its N-demethylated metabolite in plasma and blood using chiral capillary gas chromatography.
    Journal of chromatography, 1984, Apr-13, Volume: 307, Issue:1

    Topics: Anticonvulsants; Chromatography, Gas; Half-Life; Humans; Hydantoins; Mephenytoin; Stereoisomerism

1984
Stereoselective metabolism and pharmacogenetic control of 5-phenyl-5-ethylhydantoin (nirvanol) in humans.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 230, Issue:1

    Topics: Adolescent; Adult; Anticonvulsants; Half-Life; Humans; Hydantoins; Male; Mephenytoin; Stereoisomerism; Time Factors

1984
Relation of in vivo drug metabolism to stereoselective fetal hydantoin toxicology in mouse: evaluation of mephenytoin and its metabolite, nirvanol.
    The Journal of pharmacology and experimental therapeutics, 1982, Volume: 221, Issue:1

    Topics: Animals; Embryo, Mammalian; Female; Fetus; Hydantoins; Mephenytoin; Mice; Mice, Inbred ICR; Pregnancy; Stereoisomerism

1982
The synthesis of some 11C-labelled antiepileptic drugs with potential utility as radiopharmaceuticals: hydantoins and barbiturates.
    The International journal of applied radiation and isotopes, 1981, Volume: 32, Issue:11

    Topics: Anticonvulsants; Barbital; Barbiturates; Carbon Radioisotopes; Hydantoins; Isotope Labeling; Mephenytoin; Phenobarbital; Phenytoin

1981
Quantitative studies of the physiological disposition of 3-methyl-5-ethyl-5-phenyl hydantoin (mesantoin) and 5-ethyl-5-phenyl hydantoin (nirvanol).
    The Journal of pharmacology and experimental therapeutics, 1953, Volume: 109, Issue:3

    Topics: Anticonvulsants; Blood; Humans; Hydantoins; Imidazoles; Mephenytoin

1953
A pharmacological comparison of the optical isomers of 5-ethyl-5-phenyl hydantoin (nirvanol) and of 3-methyl-5-ethyl-5-phenyl hydantoin (mesantoin).
    The Journal of pharmacology and experimental therapeutics, 1954, Volume: 110, Issue:1

    Topics: Anticonvulsants; Hydantoins; Imidazoles; Mephenytoin

1954
The metabolic conversion of 3-methyl-5-ethyl-5-phenyl hydantoin (mesantoin) and of 5-ethyl-5-phenyl hydantoin (nirvanol) to 5 - ethyl -5- (p-hydroxyphenyl) hydantoin.
    The Journal of pharmacology and experimental therapeutics, 1956, Volume: 117, Issue:2

    Topics: Anticonvulsants; Hydantoins; Imidazoles; Mephenytoin

1956
[Experimental ophthalmopathic syndrome in guinea pigs caused by prolonged administration of 3-methyl-5-ethylphenylhydantoin].
    Rivista di anatomia patologica e di oncologia, 1961, Volume: 19

    Topics: Animals; Cataract; Eye Diseases; Guinea Pigs; Hydantoins; Keratitis; Mephenytoin

1961
Active-site characteristics of CYP2C19 and CYP2C9 probed with hydantoin and barbiturate inhibitors.
    Archives of biochemistry and biophysics, 2004, Sep-01, Volume: 429, Issue:1

    Topics: Aryl Hydrocarbon Hydroxylases; Barbiturates; Binding Sites; Computer Simulation; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Drug Design; Enzyme Activation; Hydantoins; Mephenytoin; Mixed Function Oxygenases; Models, Chemical; Models, Molecular; Phenobarbital; Phenytoin; Protein Binding

2004