Page last updated: 2024-08-21

ethylnitrosourea and thymine

ethylnitrosourea has been researched along with thymine in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19906 (46.15)18.7374
1990's5 (38.46)18.2507
2000's2 (15.38)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jensen, DE; Reed, DJ1
Bronstein, SM; Skopek, TR; Swenberg, JA1
Drinkwater, NR; Eckert, KA; Ingle, CA1
Rajewsky, MF; Samson, L; Thomale, J1
Burns, PA; Glickman, BW; Gordon, AJ; Kunsmann, K1
De Brij, RJ; De Graaf, A; Den Engelse, L; Menkveld, GJ1
Huh, N; Rajewsky, MF1
Burkhart, BA; Burkhart, JG; Malling, HV; Sampson, KS1
Arezina, J; Musarrat, J; Uddin, S; Wani, AA1
Koszewski, NJ; Notides, AC; Obourn, JD1
Jansen, JG; Op het Veld, CW; van Hees-Stuivenberg, S; van Zeeland, AA1
Cai, Z; Fix, D1
Bentley, L; Browne, M; Cox, RD; Goldsworthy, M; Haynes, A; Hough, T; Hugill, A; Hunter, AJ; Mijat, V; Moir, L; Quarterman, J; Spurr, N; Toye, AA1

Other Studies

13 other study(ies) available for ethylnitrosourea and thymine

ArticleYear
Reaction of DNA with alkylating agents. Quantitation of alkylation by ethylnitrosourea of oxygen and nitrogen sites on poly[dA-dT] including phosphotriester formation.
    Biochemistry, 1978, Nov-28, Volume: 17, Issue:24

    Topics: Adenine; Alkylation; Binding Sites; Deoxyribonucleases; Ethylnitrosourea; Exonucleases; Magnesium; Nitrogen; Nitrosourea Compounds; Organophosphates; Organophosphorus Compounds; Osmolar Concentration; Oxygen; Poly dA-dT; Polydeoxyribonucleotides; Sodium; Thymine

1978
Efficient repair of O6-ethylguanine, but not O4-ethylthymine or O2-ethylthymine, is dependent upon O6-alkylguanine-DNA alkyltransferase and nucleotide excision repair activities in human cells.
    Cancer research, 1992, Apr-01, Volume: 52, Issue:7

    Topics: B-Lymphocytes; Cell Line; DNA Repair; Ethylnitrosourea; Guanine; Humans; Kinetics; Methyltransferases; Models, Biological; O(6)-Methylguanine-DNA Methyltransferase; Pyrimidine Dimers; Substrate Specificity; Thymine; Time Factors

1992
N-ethyl-N-nitrosourea induces A:T to C:G transversion mutations as well as transition mutations in SOS-induced Escherichia coli.
    Carcinogenesis, 1989, Volume: 10, Issue:12

    Topics: Adenine; Base Composition; Base Sequence; Chromosome Deletion; Cytosine; DNA Damage; DNA Repair; DNA, Bacterial; Escherichia coli; Ethylnitrosourea; Genes, Bacterial; Guanine; Molecular Sequence Data; Mutation; SOS Response, Genetics; Thymine

1989
Alternative pathways for the in vivo repair of O6-alkylguanine and O4-alkylthymine in Escherichia coli: the adaptive response and nucleotide excision repair.
    The EMBO journal, 1988, Volume: 7, Issue:7

    Topics: Alkylation; DNA Repair; DNA, Bacterial; Escherichia coli; Ethylnitrosourea; Guanine; Kinetics; Methylnitrosourea; Mutation; Thymine

1988
Influence of neighboring base sequence on the distribution and repair of N-ethyl-N-nitrosourea-induced lesions in Escherichia coli.
    Cancer research, 1988, Aug-15, Volume: 48, Issue:16

    Topics: Base Sequence; DNA Repair; Escherichia coli; Ethylnitrosourea; Guanine; Methylnitronitrosoguanidine; Mutation; Thymine

1988
O2- and O4-ethylthymine and the ethylphosphotriester dTp(Et)dT are highly persistent DNA modifications in slowly dividing tissues of the ethylnitrosourea-treated rat.
    Carcinogenesis, 1987, Volume: 8, Issue:6

    Topics: Animals; Cell Division; Dinucleoside Phosphates; DNA; DNA Damage; Ethylnitrosourea; Kinetics; Male; Rats; Rats, Inbred Strains; Thymine; Thymine Nucleotides; Tissue Distribution

1987
Enzymatic elimination of O6-ethylguanine and stability of O4-ethylthymine in the DNA of malignant neural cell lines exposed to N-ethyl-N-nitrosourea in culture.
    Carcinogenesis, 1986, Volume: 7, Issue:3

    Topics: Animals; Cells, Cultured; Clone Cells; DNA Repair; Ethylnitrosourea; Guanine; Kinetics; Neurons; Rats; Thymine

1986
ENU-induced mutagenesis at a single A: T base pair in transgenic mice containing phi X174.
    Mutation research, 1993, Volume: 292, Issue:1

    Topics: Adenine; Animals; Bacteriophage phi X 174; Base Sequence; Dinucleoside Phosphates; DNA; Ethylnitrosourea; Female; Homozygote; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutagenicity Tests; Mutagens; Thymine

1993
Induction and processing of promutagenic O4-ethylthymine lesion in specific gene segments of plasmid DNA.
    Biochimica et biophysica acta, 1995, Feb-21, Volume: 1260, Issue:3

    Topics: Alkylation; DNA Adducts; DNA Damage; DNA Repair; DNA, Recombinant; Escherichia coli; Ethylnitrosourea; Plasmids; Thymine

1995
Hormone- and DNA-binding mechanisms of the recombinant human estrogen receptor.
    Biochemistry, 1993, Jun-22, Volume: 32, Issue:24

    Topics: Animals; Baculoviridae; Base Sequence; Binding Sites; Cells, Cultured; Chickens; Cloning, Molecular; DNA; Estradiol; Ethylnitrosourea; Humans; Molecular Sequence Data; Moths; Polytetrafluoroethylene; Receptors, Estrogen; Recombinant Proteins; Thymine

1993
Effect of nucleotide excision repair on hprt gene mutations in rodent cells exposed to DNA ethylating agents.
    Mutagenesis, 1997, Volume: 12, Issue:6

    Topics: Alkylating Agents; Animals; CHO Cells; Cricetinae; DNA; DNA Damage; DNA Mutational Analysis; DNA Repair; Ethyl Methanesulfonate; Ethylnitrosourea; Genes; Guanine; Hypoxanthine Phosphoribosyltransferase; Mutagenicity Tests; Mutagens; Mutation; Species Specificity; Thymine

1997
Neighboring base identity affects N-ethyl-N-nitrosourea-induced mutagenesis in Escherichia coli.
    Mutation research, 2002, Oct-31, Volume: 508, Issue:1-2

    Topics: Bacterial Proteins; Base Pairing; Codon, Nonsense; Escherichia coli; Ethylnitrosourea; Multienzyme Complexes; Mutagenesis; Thymine

2002
A new mouse model of type 2 diabetes, produced by N-ethyl-nitrosourea mutagenesis, is the result of a missense mutation in the glucokinase gene.
    Diabetes, 2004, Volume: 53, Issue:6

    Topics: Adenine; Amino Acid Sequence; Amino Acid Substitution; Animals; Chromosome Mapping; Diabetes Mellitus, Type 2; Disease Models, Animal; Ethylnitrosourea; Glucokinase; Glucose; Glucose Intolerance; Heterozygote; Homozygote; Isoleucine; Male; Mice; Mice, Mutant Strains; Molecular Sequence Data; Mutagens; Mutation, Missense; Phenylalanine; Phosphorylation; Thymine

2004