ethylnitrosourea has been researched along with thioguanine anhydrous in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (29.03) | 18.7374 |
| 1990's | 20 (64.52) | 18.2507 |
| 2000's | 2 (6.45) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bouffler, SD; Godfrey, DB; Johnson, RT; Musk, SR; Raman, MJ | 1 |
| Braun, R; Hüttner, E; Schöneich, J; Wielgosz, SM | 1 |
| Bodell, WJ | 1 |
| Aaron, CS; Albertini, RJ; O'Neill, JP; Zimmer, DM | 1 |
| Aidoo, A; Casciano, DA; Heflich, RH; Lyn-Cook, LE; Mittelstaedt, RA | 1 |
| Maher, VM; McCormick, JJ; Norimura, T | 2 |
| Imanishi, H; Matsumoto, K; Ohta, T; Sasaki, YF; Shirasu, Y; Tutikawa, K; Watanabe, M | 1 |
| Bignami, M; Calcagnile, A; Di Muccio, A; Dogliotti, E; Saffiotti, U; Terlizzese, M; Vitelli, A | 1 |
| Burkhart-Schultz, K; Crippen, TL; Jones, IM; Strout, CL | 1 |
| Burkhart-Schultz, K; Carrano, AV; Jones, IM | 2 |
| Evans, HJ | 1 |
| Kaina, B | 1 |
| Eckhardt, K; Gocke, E; King, MT; Wild, D | 1 |
| Burki, HJ; Goth-Goldstein, R | 1 |
| Brennand, J; Fox, M; McMillan, S | 1 |
| Sehlmeyer, U; Wobus, AM | 1 |
| Aidoo, A; Casciano, DA; George, EO; Heflich, RH; Lyn-Cook, LE | 1 |
| Jansen, JG; Mohn, GR; Tates, AD; van Teijlingen, CM; van Zeeland, AA; Vrieling, H | 1 |
| Aidoo, A; Lensing, S; Lyn-Cook, LE; Wamer, W | 1 |
| Heflich, RH; Mittelstaedt, RA; Smith, BA | 1 |
| Kunugita, N; Mei, N; Nomoto, S; Norimura, T | 1 |
| Horiya, N; Ikeda, H; Katoh, M; Matsui, M; Nohmi, T; Shibuya, T; Sofuni, T; Suzuki, H; Suzuki, M; Ueda, O; Watanabe, M; Yamada, M | 1 |
| Branda, RF; Lafayette, AR; Nicklas, JA; O'Neill, JP | 2 |
| Casciano, DA; Dass, SB; Heflich, RH | 1 |
| Donovan, PJ; Smith, GT | 1 |
| Chen, T; Dobrovolsky, VN; Heflich, RH | 1 |
| Hayashi, H; Kondo, H; Masumura, K; Nohmi, T; Shindo, Y | 1 |
| Donovan, PJ; Dove, LF; Klose, J; Powell, DA; Smith, GT | 1 |
31 other study(ies) available for ethylnitrosourea and thioguanine anhydrous
| Article | Year |
|---|---|
Mammalian cells share a common pathway for the relief of DNA replication arrest by O6-alkyl guanine, incorporated 6-thioguanine and UV photoproducts.
Topics: Alkylating Agents; Animals; Cell Survival; Deer; DNA Damage; DNA Replication; Ethylnitrosourea; Genes; Methylnitrosourea; Methyltransferases; Mice; Nitrogen Mustard Compounds; Sister Chromatid Exchange; Thioguanine; Transfection | 1992 |
Detection of 6-thioguanine-resistant spleen lymphocytes in different mouse strains by autoradiography.
Topics: Animals; Autoradiography; Cyclophosphamide; Ethylnitrosourea; Female; Lymphocytes; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mutation; Spleen; Thioguanine | 1991 |
Molecular dosimetry of sister chromatid exchange induction in 9L cells treated with 6-thioguanine.
Topics: Alkylating Agents; Animals; DNA Damage; Dose-Response Relationship, Drug; Ethylnitrosourea; Glioma; Nimustine; Rats; Sister Chromatid Exchange; Thioguanine; Tumor Cells, Cultured | 1991 |
Enumeration of 6-thioguanine-resistant T-lymphocytes in the peripheral blood of nonhuman primates (cynomolgus monkeys).
Topics: Animals; Cell Division; Cell Line; Clone Cells; Drug Resistance; Ethylnitrosourea; Female; Macaca fascicularis; Male; Models, Genetic; Mutagenesis; Phenotype; T-Lymphocytes; Thioguanine | 1991 |
Induction of 6-thioguanine-resistant lymphocytes in Fischer 344 rats following in vivo exposure to N-ethyl-N-nitrosourea and cyclophosphamide.
Topics: Actins; Animals; Blotting, Northern; Clone Cells; Cyclophosphamide; Drug Resistance; Ethylnitrosourea; Female; Hypoxanthine Phosphoribosyltransferase; Lymphocytes; Mutagenicity Tests; Rats; Rats, Inbred F344; RNA, Messenger; Thioguanine | 1991 |
A quantitative assay for measuring the induction of mutations in human peripheral blood T-lymphocytes.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Cell Division; Cells, Cultured; Drug Resistance; Ethylnitrosourea; Freezing; Humans; Interleukin-2; Mutagenicity Tests; Mutation; T-Lymphocytes; Thioguanine | 1990 |
Cytotoxic and mutagenic effect of UV, ethylnitrosourea and (+/-)-7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10-tetrahydrobenzo [a]pyrene in diploid human T lymphocytes in culture: comparison with fibroblasts.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adult; Cell Division; Cell Survival; Cells, Cultured; Drug Resistance; Ethylnitrosourea; Fibroblasts; Humans; Mutagenicity Tests; Mutation; T-Lymphocytes; Thioguanine; Ultraviolet Rays | 1990 |
Suppression of 6-TG-resistant mutations in V79 cells and recessive spot formations in mice by vanillin.
Topics: Acrolein; Animals; Benzaldehydes; Cells, Cultured; Coumarins; Drug Resistance; Ethylnitrosourea; Female; Male; Mice; Mice, Inbred C57BL; Mutagenicity Tests; Mutation; Pregnancy; Thioguanine; Ultraviolet Rays; X-Rays | 1990 |
Induction kinetics of mutations at two genetic loci, DNA damage and repair in CHO cells after different exposure times to N-ethyl-N-nitrosourea.
Topics: Animals; Chromosome Mapping; Cricetinae; Cricetulus; DNA; DNA Repair; Drug Resistance; Ethylnitrosourea; Hypoxanthine Phosphoribosyltransferase; Mutation; Nucleic Acid Conformation; Ouabain; Sodium-Potassium-Exchanging ATPase; Thioguanine | 1987 |
Factors that affect the frequency of thioguanine-resistant lymphocytes in mice following exposure to ethylnitrosourea.
Topics: Age Factors; Animals; Cell Division; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance; Ethylnitrosourea; Hypoxanthine Phosphoribosyltransferase; Lymphocytes; Male; Mice; Mutation; Sister Chromatid Exchange; Spleen; Thioguanine; Thymus Gland; Time Factors | 1987 |
A method to quantify spontaneous and in vivo induced thioguanine-resistant mouse lymphocytes.
Topics: Animals; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Drug Resistance; Ethylnitrosourea; Hypoxanthine Phosphoribosyltransferase; Male; Mice; Mutagenicity Tests; Mutation; Rats; T-Lymphocytes; Thioguanine | 1985 |
A study of the frequency of sister-chromatid exchange and of thioguanine-resistant cells in mouse spleen lymphocytes after in vivo exposure to ethylnitrosourea.
Topics: Animals; Drug Resistance; Ethylnitrosourea; Kinetics; Lymphocytes; Mice; Mutagenicity Tests; Nitrosourea Compounds; Sister Chromatid Exchange; Spleen; Thioguanine | 1985 |
Induction of 6-thioguanine-resistant mutants and SCEs by 3 chemical mutagens (EMS, ENU and MMC) in cultured human blood lymphocytes.
Topics: Cell Cycle; Cells, Cultured; Drug Resistance; Ethyl Methanesulfonate; Ethylnitrosourea; Humans; Hypoxanthine Phosphoribosyltransferase; Lymphocytes; Mitomycin; Mitomycins; Mutation; Nitrosourea Compounds; Sister Chromatid Exchange; Thioguanine | 1984 |
Cross-resistance studies with V79 Chinese hamster cells adapted to the mutagenic or clastogenic effect of N-methyl-N'-nitro-N-nitrosoguanidine.
Topics: Animals; Cell Line; Cell Survival; Cricetinae; Cricetulus; Drug Resistance; Ethyl Methanesulfonate; Ethylnitrosourea; Lung; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Methylnitrosourea; Mutagens; Thioguanine; Ultraviolet Rays | 1983 |
Autoradiographic detection of 6-thioguanine-resistant lymphocytes of mice. A novel system in somatic mutagenesis testing.
Topics: Animals; Autoradiography; Cells, Cultured; Dose-Response Relationship, Drug; Ethylnitrosourea; Lymphocytes; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mutagenicity Tests; Sister Chromatid Exchange; Thioguanine | 1983 |
Ethylnitrosourea-induced mutagenesis in asynchronous and synchronous Chinese hamster ovary cells.
Topics: Animals; Cell Cycle; Cell Line; Cricetinae; Cricetulus; Cytological Techniques; Drug Resistance; Ethylnitrosourea; Female; Mutagens; Mutation; Nitrosourea Compounds; Ouabain; Ovary; Thioguanine | 1980 |
Effects of metabolic inhibitors on cel lethality and mutation induction in Chinese hamster cells. II. The effect of posttreatment with non-toxic concentrations of thymidine.
Topics: Animals; Azaguanine; Cell Line; Cricetinae; Cricetulus; Deoxycytidine; Ethylnitrosourea; Lung; Methylnitrosourea; Mutation; Thioguanine; Thymidine; Ultraviolet Rays | 1981 |
Lower mutation frequencies are induced by ENU in undifferentiated embryonic cells than in differentiated cells of the mouse in vitro.
Topics: Animals; Cell Differentiation; Drug Resistance; Embryo, Mammalian; Ethylnitrosourea; Mice; Mutagenicity Tests; Mutation; Thioguanine; Tumor Cells, Cultured | 1994 |
The effect of time after treatment, treatment schedule and animal age on the frequency of 6-thioguanine-resistant T-lymphocytes induced in Fischer 344 rats by N-ethyl-N-nitrosourea.
Topics: Age Factors; Animals; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance; Ethylnitrosourea; Male; Mutagenesis; Rats; Rats, Inbred F344; T-Lymphocytes; Thioguanine; Time Factors | 1993 |
Marked differences in the role of O6-alkylguanine in hprt mutagenesis in T-lymphocytes of rats exposed in vivo to ethylmethanesulfonate, N-(2-hydroxyethyl)-N-nitrosourea, or N-ethyl-N-nitrosourea.
Topics: Adenine; Animals; Base Composition; Base Sequence; Carcinogens; DNA Adducts; DNA, Complementary; Drug Resistance; Ethyl Methanesulfonate; Ethylnitrosourea; Guanine; Hypoxanthine Phosphoribosyltransferase; In Vitro Techniques; Male; Molecular Sequence Data; Mutagenesis; Point Mutation; Polymerase Chain Reaction; Rats; Rats, Inbred Lew; T-Lymphocytes; Thioguanine; Thymidine | 1995 |
Ascorbic acid (vitamin C) modulates the mutagenic effects produced by an alkylating agent in vivo.
Topics: Administration, Oral; Analysis of Variance; Animals; Ascorbic Acid; Carcinogenicity Tests; Cells, Cultured; Dose-Response Relationship, Drug; Ethylnitrosourea; Injections, Intraperitoneal; Male; Mutagenesis; Mutagenicity Tests; Rats; Rats, Inbred F344; Spleen; T-Lymphocytes; Thioguanine; Thymus Gland; Time Factors | 1994 |
Analysis of in vivo mutation induced by N-ethyl-N-nitrosourea in the hprt gene of rat lymphocytes.
Topics: Animals; Base Composition; Base Sequence; DNA Primers; Drug Resistance; Ethylnitrosourea; Exons; Female; Hypoxanthine Phosphoribosyltransferase; Introns; Lymphocytes; Molecular Sequence Data; Mutagenesis; Point Mutation; Polymerase Chain Reaction; Rats; Rats, Inbred F344; Thioguanine | 1995 |
Comparison of the frequency of T-cell receptor mutants and thioguanine resistance induced by X-rays and ethylnitrosourea in cultured human blood T-lymphocytes.
Topics: Adult; Alkylating Agents; Ethylnitrosourea; Humans; Hypoxanthine Phosphoribosyltransferase; Immunologic Techniques; Male; Middle Aged; Mutagenicity Tests; Mutagens; Receptors, Antigen, T-Cell; T-Lymphocytes; Thioguanine; X-Rays | 1996 |
A new transgenic mouse mutagenesis test system using Spi- and 6-thioguanine selections.
Topics: Animals; Bacterial Proteins; Bacteriophage lambda; Blotting, Southern; Bone Marrow; Deoxyribonucleases, Type II Site-Specific; Drosophila Proteins; Epidermal Growth Factor; Escherichia coli; Escherichia coli Proteins; Ethylnitrosourea; Female; Gamma Rays; Genes, Reporter; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; Mutagenesis; Mutagenicity Tests; Mutagens; Pentosyltransferases; Point Mutation; Proteins; Recombination, Genetic; Selection, Genetic; Sequence Deletion; Spermatozoa; Spleen; Thioguanine | 1996 |
Effect of folate deficiency on mutations at the hprt locus in Chinese hamster ovary cells exposed to monofunctional alkylating agents.
Topics: Alkylating Agents; Animals; CHO Cells; Cricetinae; Ethyl Methanesulfonate; Ethylnitrosourea; Folic Acid Deficiency; Hypoxanthine Phosphoribosyltransferase; Mutation; Polymerase Chain Reaction; Thioguanine | 1997 |
The mutagenic response at the ouabain resistance locus in T cells of mice exposed to N-ethyl-N-nitrosourea parallels the response at the Hprt locus and correlates with mutation target size.
Topics: Animals; Chromosome Mapping; Ethylnitrosourea; Female; Hypoxanthine Phosphoribosyltransferase; Mice; Mice, Inbred C57BL; Mutagens; Mutation; Ouabain; T-Lymphocytes; Thioguanine | 1997 |
Cell sensitivity to transplacental mutagenesis by N-ethyl-N-nitrosourea is greatest during early gestation in the Syrian hamster.
Topics: Animals; Cell Division; Cells, Cultured; Cricetinae; Diphtheria Toxin; Ethylnitrosourea; Female; Gestational Age; Litter Size; Maternal-Fetal Exchange; Mesocricetus; Mutagenesis; Mutagenicity Tests; Mutagens; Mutation; Pregnancy; Thioguanine | 1999 |
The effect of folate deficiency on the hprt mutational spectrum in Chinese hamster ovary cells treated with monofunctional alkylating agents.
Topics: Alkylating Agents; Animals; Base Pairing; CHO Cells; Cricetinae; DNA Mutational Analysis; DNA Primers; DNA Repair; Ethyl Methanesulfonate; Ethylnitrosourea; Folic Acid Deficiency; Guanine; Hypoxanthine Phosphoribosyltransferase; Mutagens; Mutation; Polymerase Chain Reaction; Thioguanine | 1999 |
Molecular analysis of in vivo mutations induced by N-ethyl-N-nitrosourea in the autosomal Tk and the X-linked Hprt genes of mouse lymphocytes.
Topics: Amino Acid Substitution; Animals; Base Sequence; Bromodeoxyuridine; Carcinogens; DNA Mutational Analysis; DNA, Complementary; Drug Resistance; Ethylnitrosourea; Female; Gene Frequency; Genetic Linkage; Hypoxanthine Phosphoribosyltransferase; Loss of Heterozygosity; Lymphocytes; Male; Mice; Mice, Inbred C57BL; Mutagenicity Tests; Mutation; Point Mutation; Thioguanine; Thymidine Kinase; X Chromosome | 1999 |
Novel transgenic rat for in vivo genotoxicity assays using 6-thioguanine and Spi- selection.
Topics: Animals; Animals, Genetically Modified; Chromosome Mapping; Ethylnitrosourea; Mutagenicity Tests; Mutagens; Rats; Rats, Sprague-Dawley; Selection, Genetic; Thioguanine | 2003 |
HGPRT mutation induction by N-ethyl-N-nitrosourea as measured by 6-thioguanine resistance is higher in male than in female Syrian hamster fetuses.
Topics: Animals; Cells, Cultured; Cricetinae; Ethylnitrosourea; Female; Fetus; Hypoxanthine Phosphoribosyltransferase; Male; Mesocricetus; Mutagenesis; Pregnancy; Sex Characteristics; Thioguanine | 2006 |