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ethylketocyclazocine and naltrexone

ethylketocyclazocine has been researched along with naltrexone in 66 studies

Research

Studies (66)

Timeframe	Studies, this research(%)	All Research%
pre-1990	42 (63.64)	18.7374
1990's	21 (31.82)	18.2507
2000's	2 (3.03)	29.6817
2010's	1 (1.52)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bell, GI; Breder, CD; Kong, H; Raynor, K; Reisine, T; Takeda, J; Yasuda, K	1
Coale, EH; Hein, DW; Herling, S; Valentino, RJ; Woods, JH	2
Eades, CG; Gilbert, PE; Huppler, RE; Martin, WR; Thompson, JA	1
Craft, RM; Dykstra, LA	2
Hamann, SR; Martin, WR	1
Berzetei-Gurske, IP; Toll, L	1
Cone, EJ; Vaupel, DB	1
Abbott, FV	1
LoPresti, D; Porreca, F; Ward, SJ	1
Goldberg, SR; Katz, JL; Schindler, CW; Su, TP; Wu, XZ	1
Holtzman, SG	2
Dougall, IG; Leff, P	2
Brocklehurst, C; Devia, C; Faust, WB; Moerschbaecher, JM	1
Burks, TF; Fox, DA	1
Larson, DL; Lipkowski, AW; Nagase, H; Portoghese, PS; Takemori, AE	1
Nagase, H; Portoghese, PS; Takemori, AE	1
Ho, BY; Naeseth, JS; Portoghese, PS; Takemori, AE	1
Carino, MA; Horita, A; Yamawaki, S	1
Martin, WR; Wettstein, JG	1
Lipkowski, AW; Portoghese, PS; Takemori, AE	1
Portoghese, PS; Takemori, AE	2
Eisenberg, RM	1
Bell, RD; Cicero, TJ	1
Hiramatsu, M; Kameyama, T; Nabeshima, T	1
Hayes, AG; Skingle, M; Tyers, MB	1
Larson, DL; Portoghese, PS; Ronsisvalle, G; Takemori, AE	1
Liu-Chen, LY; Tam, SW	1
Bhargava, HN; Das, S	2
Hynes, MD; Leander, JD; Reel, JK; Zimmerman, DM	1
Portoghese, PS; Schoenecker, JW; Takemori, AE	1
Calcagnetti, DJ; Cramer, CP; Fanselow, MS; Helmstetter, FJ	1
Dykstra, LA; Gmerek, DE; Winger, G; Woods, JH	1
Brocklehurst, C; Devia, C; Moerschbaecher, JM	1
Leander, JD	1
Ludens, JH; Slizgi, GR	1
Stephens, KR; Young, AM	1
Holtzman, SG; Teal, JJ	1
Kosterlitz, HW; Paterson, SJ; Robson, LE	1
Harris, RA; Snell, D	1
Portoghese, PS; Takemori, AE; Ward, SJ	1
Takemori, AE; Ward, SJ	1
Brown, DR; Holtzman, SG; Locke, KW	1
Herling, S; Solomon, RE; Valentino, RJ; Woods, JH	1
Hein, DW; Herling, S; Woods, JH; Young, AM	1
Herling, S; Woods, JH; Young, AM	1
Duan, N; Kapusta, DR; Minor, LD; Mosaddeghi, M; Paul, D	1
Bélisle, S; Bellabarba, D; Gallo-Payet, N; Lehoux, JG; Petit, A	1
Kromer, W	1
Walker, EA; Young, AM	1
France, CP; Medzihradsky, F; Woods, JH	1
Gulati, K; Puri, S; Ray, A; Sen, P	1
Gulati, K	1
Lin, CE; Mello, NK; Negus, SS; Portoghese, PS	1
Makhay, MM; Poling, A; Young, AM	1
Fábián, G; Offermanns, S; Rottmann, M; Spicher, K; Szücs, M	1
Elde, R; Kshirsagar, T; Law, PY; Nakano, AH; Portoghese, PS	1
Holtzman, SG; Powell, KR	1
Cheong, YP; Cho, KP; Kim, CJ; Kim, JK; Kim, KW; Kwun, J; Woo, RS	1
Butelman, ER; Ko, MC; Kreek, MJ; Traynor, JR; Vivian, JA; Woods, JH	1
Li, M; McMillan, DE; Wessinger, WD	1

Other Studies

66 other study(ies) available for ethylketocyclazocine and naltrexone

Article	Year
Cloning and functional comparison of kappa and delta opioid receptors from mouse brain. Proceedings of the National Academy of Sciences of the United States of America, 1993, Jul-15, Volume: 90, Issue:14 Topics: Amino Acid Sequence; Animals; Base Sequence; Brain Chemistry; Cloning, Molecular; In Situ Hybridization; Mice; Molecular Sequence Data; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Somatostatin; RNA, Messenger; Sequence Homology, Amino Acid; Substrate Specificity; Tissue Distribution	1993
Narcotic drug discriminations by rhesus monkeys and pigeons. NIDA research monograph, 1979, Volume: 27 Topics: Animals; Columbidae; Cyclazocine; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Discrimination Learning; Dose-Response Relationship, Drug; Enkephalins; Ethylketocyclazocine; Etorphine; Hormones; Macaca; Macaca mulatta; Naltrexone; Narcotics; Phenazocine	1979
The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog. The Journal of pharmacology and experimental therapeutics, 1976, Volume: 197, Issue:3 Topics: Animals; Apomorphine; Cyclazocine; Cyclopropanes; Dextropropoxyphene; Dogs; Ethylketocyclazocine; Humans; Morphinans; Morphine; Morphine Dependence; Nalorphine; Naltrexone; Phenazocine; Spinal Cord	1976
Agonist and antagonist activity of kappa opioids in the squirrel monkey: I. Antinociception and urine output. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Behavior, Animal; Benzodiazepines; Benzomorphans; Drug Interactions; Ethylketocyclazocine; Male; Methadone; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Nociceptors; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Saimiri; Urination	1992
Agonist and antagonist activity of kappa opioids in the squirrel monkey: II. Effect of chronic morphine treatment. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Benzodiazepines; Benzomorphans; Drug Interactions; Drug Tolerance; Ethylketocyclazocine; Male; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Nociceptors; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Saimiri; Shock; Time Factors	1992
Opioid and nicotinic analgesic and hyperalgesic loci in the rat brain stem. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 261, Issue:2 Topics: Analgesia; Animals; Brain Stem; Dose-Response Relationship, Drug; Ethylketocyclazocine; Female; Mecamylamine; Microinjections; Naltrexone; Nicotine; Rats; Rats, Inbred Strains; Receptors, Opioid	1992
The mu-opioid activity of kappa-opioid receptor agonist compounds in the guinea pig ileum. European journal of pharmacology, 1992, Mar-03, Volume: 212, Issue:2-3 Topics: Animals; Ethylketocyclazocine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nalorphine; Naltrexone; Phenazocine; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu	1992
Pharmacodynamic and pharmacokinetic actions of ketocyclazocine enantiomers in the dog: absence of sigma- or phencyclidine-like activity. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 256, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Behavior, Animal; Dogs; Dose-Response Relationship, Drug; Drug Administration Schedule; Ethylketocyclazocine; Female; Morphine; Naltrexone; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, sigma; Stereoisomerism; Time Factors	1991
beta-Funaltrexamine antagonizes the analgesic effects of mu and kappa agonists in the formalin test. Pharmacology, biochemistry, and behavior, 1990, Volume: 37, Issue:4 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Dose-Response Relationship, Drug; Ethylketocyclazocine; Formaldehyde; Male; Morphine; Naltrexone; Narcotic Antagonists; Pain; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Urination	1990
Opioid agonist affinity in the guinea-pig ileum and mouse vas deferens. European journal of pharmacology, 1990, Apr-10, Volume: 179, Issue:1-2 Topics: Animals; Cyclazocine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Guinea Pigs; Ileum; Male; Methadone; Mice; Morphine; Morphine Derivatives; Naltrexone; Receptors, Opioid; Vas Deferens	1990
Enhanced sensitivity to behavioral effects of naltrexone in rats. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 252, Issue:1 Topics: Animals; Conditioning, Psychological; Cyclazocine; Dose-Response Relationship, Drug; Ethylketocyclazocine; Male; Morphine; Naloxone; Naltrexone; Rats; Salivation	1990
Opioid- and phencyclidine-like discriminative effects of ditolylguanidine, a selective sigma ligand. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:3 Topics: Animals; Benzomorphans; Cyclazocine; Discrimination Learning; Ethylketocyclazocine; Generalization, Psychological; Guanidines; Haloperidol; Levorphanol; Male; Naltrexone; Narcotics; Phencyclidine; Rats; Receptors, Opioid; Receptors, sigma; Stereoisomerism	1989
Estimation of affinities and efficacies for kappa-receptor agonists in guinea-pig ileum. British journal of pharmacology, 1989, Volume: 96, Issue:3 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Binding, Competitive; Cyclazocine; Electric Stimulation; Ethylketocyclazocine; Guinea Pigs; In Vitro Techniques; Male; Models, Biological; Morphinans; Muscle, Smooth; Naltrexone; Narcotic Antagonists; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa	1989
Effects of kappa agonists and dexoxadrol on the acquisition of conditional discriminations in monkeys. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:2 Topics: Analgesics; Animals; Benzomorphans; Conditioning, Psychological; Cyclazocine; Dioxolanes; Dioxoles; Discrimination Learning; Dose-Response Relationship, Drug; Erythrocebus patas; Ethylketocyclazocine; Female; Macaca fascicularis; Male; Naltrexone; Piperidines; Receptors, Opioid; Receptors, Opioid, kappa	1987
Roles of central and peripheral mu, delta and kappa opioid receptors in the mediation of gastric acid secretory effects in the rat. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 244, Issue:2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Brain; Cyclazocine; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ethylketocyclazocine; Gastric Acid; Male; Morphine; Naltrexone; Pyrrolidines; Quaternary Ammonium Compounds; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu	1988
Binaltorphimine-related bivalent ligands and their kappa opioid receptor antagonist selectivity. Journal of medicinal chemistry, 1988, Volume: 31, Issue:4 Topics: Animals; Chemical Phenomena; Chemistry; Cyclazocine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Guinea Pigs; Male; Mice; Models, Molecular; Morphine; Muscle, Smooth; Naltrexone; Receptors, Opioid; Receptors, Opioid, kappa; Structure-Activity Relationship	1988
Only one pharmacophore is required for the kappa opioid antagonist selectivity of norbinaltorphimine. Journal of medicinal chemistry, 1988, Volume: 31, Issue:7 Topics: Animals; Chemical Phenomena; Chemistry; Cyclazocine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Guinea Pigs; Ileum; Male; Mice; Morphine; Naltrexone; Receptors, Opioid; Receptors, Opioid, kappa; Stereoisomerism; Structure-Activity Relationship; Vas Deferens	1988
Nor-binaltorphimine, a highly selective kappa-opioid antagonist in analgesic and receptor binding assays. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Animals; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Guinea Pigs; Male; Mice; Morphine; Naltrexone; Oligopeptides; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa	1988
Estimation of opioid receptor agonist dissociation constants with beta-chlornaltrexamine, an irreversible ligand which also displays agonism. British journal of pharmacology, 1988, Volume: 95, Issue:1 Topics: Animals; Cyclazocine; Drug Interactions; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Ethylketocyclazocine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphinans; Muscle, Smooth; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu	1988
Analeptic effect of opiate receptor agonists in rabbits. Neuroscience letters, 1985, Mar-22, Volume: 55, Issue:1 Topics: Animals; Arousal; Brain; Central Nervous System Stimulants; Codeine; Cyclazocine; Dose-Response Relationship, Drug; Enkephalin, Methionine; Ethylketocyclazocine; Etorphine; Male; Meperidine; Methadone; Morphine; Naltrexone; Narcotics; Phenazocine; Rabbits; Receptors, Opioid; Reflex	1985
An analysis of naltrexone and naloxone's possible agonistic actions in the dog. Drug and alcohol dependence, 1985, Volume: 15, Issue:4 Topics: Analgesics, Opioid; Animals; Cyclazocine; Dogs; Drug Synergism; Electroencephalography; Ethylketocyclazocine; Evoked Potentials; Female; Fentanyl; Morphine; Naloxone; Naltrexone; Reaction Time; Reflex; Reflex, Pupillary	1985
Binaltorphimine and nor-binaltorphimine, potent and selective kappa-opioid receptor antagonists. Life sciences, 1987, Mar-30, Volume: 40, Issue:13 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Chemical Phenomena; Chemistry; Cyclazocine; Dynorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Guinea Pigs; Male; Mice; Morphine; Naloxone; Naltrexone; Pyrrolidines; Rabbits; Receptors, Opioid; Receptors, Opioid, kappa	1987
TENA, a selective kappa opioid receptor antagonist. Life sciences, 1985, Feb-25, Volume: 36, Issue:8 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Azocines; Benzomorphans; Cyclazocine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Guinea Pigs; Ileum; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Vas Deferens	1985
Plasma corticosterone changes in response to central or peripheral administration of kappa and sigma opiate agonists. The Journal of pharmacology and experimental therapeutics, 1985, Volume: 233, Issue:3 Topics: Animals; Brain; Corticosterone; Cyclazocine; Ethylketocyclazocine; Humans; Hypothalamo-Hypophyseal System; Male; Morphine; Naloxone; Naltrexone; Opioid-Related Disorders; Phenazocine; Pituitary-Adrenal System; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Receptors, sigma	1985
A radiolabeled-ligand-binding technique for the characterization of opioid receptors in the intact mouse vas deferens. Analytical biochemistry, 1985, Volume: 150, Issue:1 Topics: Animals; Binding, Competitive; Cyclazocine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; In Vitro Techniques; Kinetics; Male; Mice; Morphine; Naltrexone; Radioligand Assay; Receptors, Opioid; Vas Deferens	1985
Phencyclidine-induced stereotyped behaviors after injection of ethylketocyclazocine, Mr 2266 and naltrexone in rats. Brain research, 1986, Jul-23, Volume: 378, Issue:2 Topics: Animals; Benzomorphans; Cyclazocine; Drug Interactions; Ethylketocyclazocine; Male; Motor Skills; Naltrexone; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, Opioid; Stereotyped Behavior	1986
Reversal by beta-funaltrexamine of the antinociceptive effect of opioid agonists in the rat. British journal of pharmacology, 1986, Volume: 88, Issue:4 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzodiazepines; Buprenorphine; Cyclazocine; Ethylketocyclazocine; Fentanyl; Male; Naltrexone; Pain; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu	1986
Synthesis and opioid antagonist potencies of naltrexamine bivalent ligands with conformationally restricted spacers. Journal of medicinal chemistry, 1986, Volume: 29, Issue:9 Topics: Animals; Biological Assay; Chemical Phenomena; Chemistry; Cyclazocine; Endorphins; Ethylketocyclazocine; Guinea Pigs; Ileum; Molecular Conformation; Morphine; Muscle Contraction; Naltrexone; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Structure-Activity Relationship	1986
Reversible and irreversible binding of beta-funaltrexamine to mu, delta and kappa opioid receptors in guinea pig brain membranes. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:2 Topics: Animals; Brain; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Ethylmaleimide; Guinea Pigs; Kinetics; Male; Membranes; Naloxone; Naltrexone; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sodium Chloride	1986
Selective proliferation of brain kappa opiate receptors in spontaneously hypertensive rats. Life sciences, 1986, Dec-29, Volume: 39, Issue:26 Topics: Animals; Binding, Competitive; Brain; Cyclazocine; Enkephalin, Leucine; Ethylketocyclazocine; Kinetics; Male; Naltrexone; Oligopeptides; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Receptors, Opioid; Receptors, Opioid, kappa	1986
Unidirectional interaction between thyrotropin releasing hormone and opiates at the level of their brain receptors. General pharmacology, 1987, Volume: 18, Issue:1 Topics: Animals; Brain; Cyclazocine; Enkephalin, Leucine; Ethylketocyclazocine; Male; Naltrexone; Oligopeptides; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Opioid; Thyrotropin-Releasing Hormone	1987
Use of beta-funaltrexamine to determine mu opioid receptor involvement in the analgesic activity of various opioid ligands. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Animals; Biological Assay; Buprenorphine; Butorphanol; Cyclazocine; Dose-Response Relationship, Drug; Ethylketocyclazocine; Etorphine; Fentanyl; Methadone; Mice; Morphine; Muscle Contraction; Nalbuphine; Nalorphine; Naltrexone; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, mu	1987
Nonequilibrium opioid antagonist activity of 6,14-dideoxynaltrexone derivatives. Journal of medicinal chemistry, 1987, Volume: 30, Issue:6 Topics: Animals; Cyclazocine; Dose-Response Relationship, Drug; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Guinea Pigs; Mice; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Structure-Activity Relationship	1987
Ethylketocyclazocine and bremazocine analgesia in neonatal rats. Pharmacology, biochemistry, and behavior, 1988, Volume: 30, Issue:4 Topics: Analgesia; Analgesics; Animals; Animals, Newborn; Benzomorphans; Cyclazocine; Ethylketocyclazocine; Female; Male; Morphinans; Naltrexone; Narcotic Antagonists; Rats	1988
Kappa opioids in rhesus monkeys. II. Analysis of the antagonistic actions of quadazocine and beta-funaltrexamine. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Azocines; Benzomorphans; Cyclazocine; Diuresis; Endorphins; Ethylketocyclazocine; Female; Hot Temperature; Macaca mulatta; Male; Morphine; Naltrexone; Narcotic Antagonists; Pyrrolidines; Reaction Time; Tail	1987
Differential antagonism by naltrexone of the effects of opioids on a fixed-ratio discrimination in rats. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 244, Issue:1 Topics: Animals; Conditioning, Operant; Cyclazocine; Discrimination Learning; Dose-Response Relationship, Drug; Ethylketocyclazocine; Male; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Pentazocine; Rats	1988
Comparative antagonism by naltrexone and naloxone of mu, kappa, and delta agonists. European journal of pharmacology, 1984, Sep-03, Volume: 104, Issue:1-2 Topics: Animals; Cyclazocine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Vas Deferens	1984
Effects of full and partial kappa agonists and mu agonists on urine output of normally hydrated rats. Neuropeptides, 1984, Volume: 5, Issue:1-3 Topics: Animals; Benzomorphans; Cyclazocine; Diuresis; Ethylketocyclazocine; Naltrexone; Narcotics; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu	1984
Studies on the nature and mechanism of the diuretic activity of the opioid analgesic ethylketocyclazocine. The Journal of pharmacology and experimental therapeutics, 1982, Volume: 220, Issue:3 Topics: Analgesics, Opioid; Animals; Body Water; Bufo marinus; Cyclazocine; Diuretics; Dose-Response Relationship, Drug; Ethylketocyclazocine; Male; Naltrexone; Radioimmunoassay; Rats; Rats, Inbred Strains; Urinary Bladder; Vasopressins	1982
Antagonism of the discriminative effects of ethylketazocine, cyclazocine, and nalorphine in macaques. Psychopharmacology, 1984, Volume: 84, Issue:3 Topics: Analgesics, Opioid; Animals; Cyclazocine; Discrimination, Psychological; Ethylketocyclazocine; Macaca mulatta; Macaca nemestrina; Male; Nalorphine; Naltrexone; Narcotic Antagonists	1984
Discriminative stimulus effects of prototype opiate receptor agonists in monkeys. European journal of pharmacology, 1980, Nov-07, Volume: 68, Issue:1 Topics: Animals; Apomorphine; Cyclazocine; Ethylketocyclazocine; Female; Generalization, Stimulus; Haloperidol; Male; Models, Biological; Morphine; Naltrexone; Phenazocine; Prejudice; Receptors, Opioid; Saimiri	1980
Characterization of the kappa-subtype of the opiate receptor in the guinea-pig brain. British journal of pharmacology, 1981, Volume: 73, Issue:4 Topics: Animals; Benzomorphans; Binding Sites; Binding, Competitive; Brain; Cyclazocine; Dihydromorphine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Guinea Pigs; Naloxone; Naltrexone; Narcotics; Phenoxybenzamine; Receptors, Opioid	1981
Interactions between narcotic agonists, partial agonists andd antagonists evaluated by punished an unpunished behavior in the rat. Psychopharmacology, 1982, Volume: 76, Issue:2 Topics: Animals; Conditioning, Psychological; Cyclazocine; Dose-Response Relationship, Drug; Ethylketocyclazocine; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Phenazocine; Punishment; Rats; Rats, Inbred Strains; Receptors, Opioid	1982
Improved assays for the assessment of kappa- and delta-properties of opioid ligands. European journal of pharmacology, 1982, Nov-19, Volume: 85, Issue:2 Topics: Animals; Cyclazocine; Ethylketocyclazocine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Morphine; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Vas Deferens	1982
Relative involvement of receptor subtypes in opioid-induced inhibition of gastrointestinal transit in mice. The Journal of pharmacology and experimental therapeutics, 1983, Volume: 224, Issue:2 Topics: Animals; Charcoal; Cyclazocine; Drug Interactions; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Female; Gastrointestinal Motility; Male; Mice; Morphine; Nalorphine; Naltrexone; Receptors, Opioid	1983
Effects of opiate antagonists and putative mu- and kappa-agonists on milk intake in rat and squirrel monkey. Pharmacology, biochemistry, and behavior, 1982, Volume: 17, Issue:6 Topics: Animals; Buprenorphine; Cyclazocine; Diazepam; Diprenorphine; Drinking; Ethylketocyclazocine; Etorphine; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Saimiri; Taste	1982
Narcotic discrimination in pigeons: antagonism by naltrexone. European journal of pharmacology, 1984, Oct-01, Volume: 105, Issue:1-2 Topics: Animals; Columbidae; Cyclazocine; Discrimination, Psychological; Dose-Response Relationship, Drug; Ethylketocyclazocine; Meperidine; Morphine; Naloxone; Naltrexone; Narcotics	1984
Phencyclidine-like discriminative stimulus properties of psychotomimetic opioids. Annals of the New York Academy of Sciences, 1982, Volume: 398 Topics: Animals; Columbidae; Cyclazocine; Discrimination, Psychological; Ethylketocyclazocine; Generalization, Psychological; Generalization, Stimulus; Morphine; Naltrexone; Phencyclidine; Rats; Saimiri	1982
Narcotic discrimination in pigeons. The Journal of pharmacology and experimental therapeutics, 1980, Volume: 214, Issue:1 Topics: Animals; Clonidine; Codeine; Columbidae; Cyclazocine; Discrimination Learning; Dose-Response Relationship, Drug; Ethylketocyclazocine; Ketamine; Meperidine; Morphine; Nalorphine; Naltrexone; Narcotics; Pentazocine; Pentobarbital; Species Specificity	1980
Pharmacological analysis of the discriminative stimulus characteristics of ethylketazocine in the rhesus monkey. The Journal of pharmacology and experimental therapeutics, 1981, Volume: 218, Issue:1 Topics: Animals; Cyclazocine; Dextrorphan; Dose-Response Relationship, Drug; Ethylketocyclazocine; Ketamine; Macaca mulatta; Naltrexone; Narcotic Antagonists; Narcotics; Phencyclidine; Prejudice; Stereoisomerism	1981
Classification of narcotics on the basis of their reinforcing, discriminative, and antagonist effects in rhesus monkeys. Federation proceedings, 1982, Volume: 41, Issue:2 Topics: Animals; Behavior, Animal; Conditioning, Operant; Cyclazocine; Discrimination, Psychological; Ethylketocyclazocine; Humans; Macaca; Macaca mulatta; Morphine; Naloxone; Naltrexone; Narcotics; Opioid-Related Disorders; Reinforcement, Psychology; Self Administration	1982
Effects of kappa-opioid receptor agonists on stimulated phosphoinositide hydrolysis in rat kidney. European journal of pharmacology, 1995, May-26, Volume: 289, Issue:3 Topics: Animals; Carbachol; Ethylketocyclazocine; Hydrolysis; In Vitro Techniques; Kidney Cortex; Male; Naltrexone; Norepinephrine; Phosphatidylinositols; Rats; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Stimulation, Chemical	1995
The modulation of placental lactogen release by opioids: a role for extracellular calcium. Molecular and cellular endocrinology, 1993, Volume: 90, Issue:2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenylate Cyclase Toxin; Analgesics; Calcium; Cells, Cultured; Dopamine; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Ethylketocyclazocine; Gene Expression Regulation; Humans; Ionomycin; Naloxone; Naltrexone; Narcotics; Pertussis Toxin; Placental Lactogen; Pyrrolidines; Time Factors; Trophoblasts; Virulence Factors, Bordetella	1993
Unexpected prosecretory action component of loperamide at mu-opioid receptors in the guinea-pig colonic mucosa in vitro. British journal of pharmacology, 1995, Volume: 114, Issue:4 Topics: Alprostadil; Amino Acid Sequence; Animals; Chlorides; Colon; Dose-Response Relationship, Drug; Ethylketocyclazocine; Guinea Pigs; Intestinal Mucosa; Loperamide; Male; Molecular Sequence Data; Naloxone; Naltrexone; Patch-Clamp Techniques; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin; Theophylline	1995
Discriminative-stimulus effects of the low efficacy mu agonist nalbuphine. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Discrimination, Psychological; Dose-Response Relationship, Drug; Ethylketocyclazocine; Male; Nalbuphine; Nalorphine; Naltrexone; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Self Administration	1993
Comparison of kappa opioids in rhesus monkeys: behavioral effects and receptor binding affinities. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:1 Topics: Analgesics; Animals; Behavior, Animal; Binding Sites; Ethylketocyclazocine; Female; Macaca mulatta; Male; Molecular Structure; Naltrexone; Narcotics; Receptors, Opioid, kappa; Respiration	1994
Role of kappa opioid receptors during stress responsiveness in rats. Indian journal of experimental biology, 1993, Volume: 31, Issue:2 Topics: Animals; Benzomorphans; Corticosterone; Ethylketocyclazocine; Male; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Opioid, kappa; Stomach Ulcer; Stress, Physiological	1993
Differential effects of intrahypothalamic administration of opioids on food intake in naive and tolerant rats. Pharmacology, biochemistry, and behavior, 1995, Volume: 52, Issue:4 Topics: Animals; Eating; Ethylketocyclazocine; Hypothalamus; Male; Morphine; Naltrexone; Narcotics; Rats; Rats, Wistar; Time Factors	1995
Effects of kappa opioids on cocaine self-administration by rhesus monkeys. The Journal of pharmacology and experimental therapeutics, 1997, Volume: 282, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Circadian Rhythm; Cocaine; Dose-Response Relationship, Drug; Ethylketocyclazocine; Female; Macaca mulatta; Male; Naloxone; Naltrexone; Pyrrolidines; Receptors, Opioid, kappa; Self Administration; Substance-Related Disorders	1997
Establishing morphine and U-50,488H as discriminative stimuli in a three-choice assay with pigeons. Experimental and clinical psychopharmacology, 1998, Volume: 6, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Animals; Columbidae; Dextroamphetamine; Discrimination Learning; Discrimination, Psychological; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Ethylketocyclazocine; Generalization, Response; Morphine; Naltrexone; Narcotic Antagonists; Narcotics	1998
Receptor-mediated activation of G-proteins by kappa opioid agonists in frog (Rana esculenta) brain membranes. Brain research bulletin, 1998, Mar-15, Volume: 45, Issue:5 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Benzomorphans; Brain; Cell Membrane; Ethylketocyclazocine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Naltrexone; Narcotic Antagonists; Rana esculenta; Receptors, Opioid, kappa	1998
NTI4F: a non-peptide fluorescent probe selective for functional delta opioid receptors. Neuroscience letters, 1998, Jun-19, Volume: 249, Issue:2-3 Topics: Animals; Bridged-Ring Compounds; Cell Line; Dogs; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Fluorescent Dyes; Imides; Microscopy, Confocal; Microscopy, Fluorescence; Morphine; Naltrexone; Receptors, Opioid, delta; Transfection	1998
Differential antagonism of the rate-decreasing effects of kappa-opioid receptor agonists by naltrexone and norbinaltorphimine. European journal of pharmacology, 1999, Jul-14, Volume: 377, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Behavior, Animal; Benzeneacetamides; Benzofurans; Benzomorphans; Conditioning, Operant; Dose-Response Relationship, Drug; Ethylketocyclazocine; Nalorphine; Naltrexone; Narcotic Antagonists; Pyrroles; Pyrrolidines; Receptors, Opioid, kappa; Reinforcement Schedule; Saimiri; Thiophenes	1999
Receptor selectivity of Met-enkephalin-Arg6-Phe7, an endogenous opioid peptide, in cerebral cortex of human and rat. Life sciences, 2000, May-26, Volume: 67, Issue:1 Topics: Adult; Animals; Benzeneacetamides; Benzomorphans; Binding Sites; Cerebral Cortex; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Ethylketocyclazocine; Female; Humans; Male; Naloxone; Naltrexone; Norepinephrine; Oligopeptides; Peptide Fragments; Peptides; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin	2000
GR89,696: a potent kappa-opioid agonist with subtype selectivity in rhesus monkeys. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 298, Issue:3 Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Benzeneacetamides; Cerebral Cortex; Discrimination, Psychological; Diuresis; Ethylketocyclazocine; Female; Guanosine 5'-O-(3-Thiotriphosphate); Macaca mulatta; Male; Membranes; Muscle Relaxation; Naltrexone; Pain Measurement; Piperazines; Prolactin; Pyrrolidines; Radioligand Assay; Receptors, Opioid, kappa; Respiratory Mechanics	2001
Drug discrimination in pigeons trained to discriminate among morphine, U50488, a combination of these drugs, and saline. Behavioural pharmacology, 2011, Volume: 22, Issue:5-6 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Butorphanol; Columbidae; Discrimination Learning; Dose-Response Relationship, Drug; Ethylketocyclazocine; Male; Morphine; Naltrexone; Narcotic Antagonists; Pentazocine; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reinforcement Schedule; Sodium Chloride	2011