ethylketocyclazocine has been researched along with naloxone in 190 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 163 (85.79) | 18.7374 |
| 1990's | 26 (13.68) | 18.2507 |
| 2000's | 1 (0.53) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Akil, H; Goldstein, A; Mansour, A; Meng, F; Thompson, RC; Watson, SJ; Xie, GX | 1 |
| Bell, GI; Breder, CD; Kong, H; Raynor, K; Reisine, T; Takeda, J; Yasuda, K | 1 |
| Chen, C; Li, JG; Liu-Chen, LY; Luo, LY; Zhu, J | 1 |
| Bélisle, S; Bellabarba, D; Gallo-Payet, N; Lehoux, JG; Petit, A | 2 |
| Chiba, S; Nishida, N; Yasuhara, Y | 1 |
| Gent, JP; Goodchild, CS; Serrao, JM | 1 |
| Negus, SS; Picker, MJ; Powell, KR | 1 |
| Benyhe, S; Maderspach, K; Németh, K; Simon, J; Szücs, M; Wollemann, M | 1 |
| Kornetsky, C; Pollock, J | 1 |
| Bartness, TJ; Billington, CJ; Herman, BH; Levine, AS; Morley, JE | 1 |
| Bettaney, J; Dray, A; James, IF; Ketchum, SB; Perkins, MN | 1 |
| Doty, P; Dykstra, LA; Mattox, SR; Negus, SS; Picker, MJ | 1 |
| Benyhe, S; Borsodi, A; Hepp, J; Magyar, A; Varga, E; Wollemann, M | 1 |
| Goldberg, SR; Schindler, CW; White, MF | 1 |
| Clark, WC; Haertzen, CA; Janal, MN; Kumor, KM | 1 |
| Goldberg, SR; Katz, JL; Schindler, CW; Su, TP; Wu, XZ | 1 |
| Chahl, LA | 1 |
| Ahmed, MS; Cavinato, AG; Maulik, D; Zhou, DH | 1 |
| deGroat, WC; Hisamitsu, T; Nagel, J; Roppolo, JR; Thor, KB; Tuttle, P | 1 |
| Bueno, L; Gué, M; Junien, JL | 1 |
| Clark, JA; Edelson, M; Hersh, B; Liu, L; Pasternak, GW; Price, M | 1 |
| Cornfeldt, M; Fielding, S; Gorney, B; Locke, KW | 1 |
| Dykstra, LA; Picker, MJ | 1 |
| Dick, W; Jakob, H; Mertzlufft, F; Nawrath, H; Rupp, J; Sack, U | 1 |
| Kameyama, T; Ukai, M | 1 |
| Deviche, P; Moore, FL | 1 |
| Dykstra, LA; Massie, CA; Picker, M | 1 |
| Ishizuka, Y; Oka, T | 1 |
| Cowan, A; Gmerek, DE | 3 |
| Dashwood, MR; Muddle, JR; Spyer, KM | 1 |
| Bicknell, RJ; Chapman, C; Leng, G | 1 |
| Bryant, HU; Lowy, MT; Malven, PV; Steele, TD; Yim, GK | 1 |
| Martin, WR; Wettstein, JG | 1 |
| Falke, NE; Fischer, EG; Martin, R | 1 |
| Cho, N; Hirobe, M; Koike, K; Konno, F; Okumura, K; Takayanagi, I | 1 |
| Buder, M; Fuder, H; Riers, HD; Rothacher, G | 1 |
| Brenner, AS; Geppert, M; Illes, P; Jackisch, R | 1 |
| Burks, TF; Deupree, D; Hruby, V; Hsiao, S; Mosberg, HI; Porreca, F; Spencer, RL | 1 |
| Inoki, R; Kudo, T; Ohkubo, T; Shibata, M; Takahashi, H | 1 |
| Lipkowski, AW; Portoghese, PS; Takemori, AE | 1 |
| Itoh, Y; Nishibori, M; Oishi, R; Saeki, K | 1 |
| Russell, NJ; Schaible, HG; Schmidt, RF | 1 |
| Dickenson, AH; Knox, RJ | 1 |
| Katz, JL | 1 |
| Benyhe, S; Borsodi, A; Hepp, J; Khan, A; Medzihradszky, K; Simon, J; Szücs, M; Wollemann, M | 1 |
| Inoki, R; Maeda, S; Nakamae, J | 1 |
| Buéno, L; Gué, M; Hondé, C; Junien, JL; Pascaud, X | 1 |
| Bianchi, C; Siniscalchi, A | 1 |
| Abbott, FV | 1 |
| Agbas, A; Avni Oktem, H; Borsodi, A; Simon, J; Varga, E | 1 |
| Adler, MW; Geller, EB; Rowan, CH | 1 |
| George, R; Pechnick, R; Poland, RE | 1 |
| Hirst, M; Kavaliers, M | 1 |
| Portoghese, PS; Takemori, AE | 2 |
| Ensinger, HA | 2 |
| Adler, MW; Geller, EB; Kirby, A; Messner, S; Robin, M | 1 |
| Neil, A | 1 |
| Hayes, A; Kelly, A | 1 |
| Eisenberg, RM | 2 |
| Grace, M; Kneip, J; Levine, AS; Morley, JE; Shearman, GT; Zeugner, H | 1 |
| Bucarelli, A; De Montis, MG; Devoto, P; Tagliamonte, A | 1 |
| Gosnell, BA; Levine, AS; Morley, JE; Waggoner, DW | 1 |
| DeRossett, SE; Holtzman, SG | 2 |
| Kameyama, T; Matsuno, K; Nabeshima, T | 1 |
| Barber, DJ; Cooper, SJ; Jackson, A; Moores, WR | 1 |
| Bidlack, JM; Denton, RR | 1 |
| Malone, MH; Matos, FF | 1 |
| Bettermann, R; Illes, P | 1 |
| Aoki, K; Ishii, K; Kajiwara, M; Matsumiya, T; Numata, H; Oka, T | 1 |
| Kamei, H; Kameyama, T; Matsuno, K; Nabeshima, T | 1 |
| Su, TP; Weissman, AD; Yeh, SY | 1 |
| Brown, SR; Cote, TE; Cox, BM; Puttfarcken, P; Werling, LL | 1 |
| Goldberg, S; Haertzen, C; Johnson, RE; Kumor, K; Su, TP; Vaupel, B | 1 |
| Seelhorst, A; Starke, K | 1 |
| Hiramatsu, M; Kameyama, T; Nabeshima, T | 1 |
| Liu-Chen, LY; Tam, SW | 1 |
| Abbott, FV; Franklin, KB; Libman, RB | 1 |
| Hölting, T; Limberger, N; Späth, L; Starke, K | 1 |
| Barr, GA; Giordano, J | 1 |
| Poncet, J; Reny-Palasse, V; Rips, R | 1 |
| Gardner, EL; Vaysse, PJ; Zukin, RS | 1 |
| Bagley, RB; Compton, DR; Katzen, JS; Martin, BR | 1 |
| Catt, KJ; Dufau, ML; Stojilković, SS | 1 |
| Gosnell, BA; Levine, AS; Morley, JE; Romsos, DR | 2 |
| Fujii, A; Ishizuka, Y; Kenjo, T; Oka, T | 1 |
| Haertzen, CA; Jasinski, DR; Johnson, RE; Kumor, KM | 1 |
| Benyhe, S; Wollemann, M | 1 |
| Gormezano, I; Harvey, JA; Schindler, CW | 1 |
| Dykstra, LA; Picker, M | 1 |
| Goldberg, SR; Katz, JL | 1 |
| Spoerlein, MT; Szewczak, MR | 1 |
| Blackburn, TP; Borkowski, KR; Friend, J; Rance, MJ | 1 |
| Dykstra, LA; Heise, JW; Picker, M | 1 |
| Costa, T; Dunn, LL; Hubbell, CL; Hunter, GA; Reid, LD | 1 |
| Collins, RJ; Tang, AH | 1 |
| Bergman, J; Hassoun, J; Schuster, CR | 1 |
| Levine, AS; Morley, JE; Wager-Srdar, S | 1 |
| Cooper, SJ; Turkish, S | 1 |
| Fitzjarrell, AT; Heath, RG; Walker, CF | 1 |
| Leander, JD | 3 |
| Bryant, HU; Malven, PV; Yim, GK | 1 |
| Ensinger, H; Hedler, L; Schurr, C; Starke, K | 1 |
| Gosnell, BA; Levine, AS; Morley, JE | 2 |
| Huidobro-Toro, JP; Parada, S | 1 |
| Corbett, AD; Gillan, MG; Kosterlitz, HW; McKnight, AT; Paterson, SJ; Robson, LE | 1 |
| Aceto, MD | 1 |
| Buchan, P; Smith, TW | 1 |
| Adler, MW; Cowan, A; Tortella, FC | 1 |
| Chavkin, C; Goldstein, A; James, IF | 1 |
| Miller, RJ | 1 |
| Huidobro-Toro, JP; Lee, NM; Löh, HH; Way, EL; Yoshimura, K | 1 |
| Cowan, A; Porreca, F; Raffa, RB; Tallarida, RJ | 1 |
| Tung, AS; Yaksh, TL | 1 |
| Huidobro-Toro, JP; Way, EL; Yoshimura, K | 1 |
| Garzón, J; Jen, MF; Lee, NM | 1 |
| Kamerling, SG; Martin, WR; Wettstein, JG; Wu, KM | 1 |
| Huidobro-Toro, JP; Lee, NM; Loh, HH; Way, EL; Zhu, YX | 1 |
| Enger, M; Grynne, BH; Holmen, AT; Maurset, AR | 1 |
| Garzón, J; Gerhart, J; Lee, NM; Loh, HH; Sánchez-Blázquez, P | 1 |
| Billington, CJ; Gerritsen, GC; Levine, AS; Morley, JE | 1 |
| Gautret, B; Schmitt, H | 1 |
| Pairet, M; Ruckebusch, Y | 1 |
| Rezvani, A; Way, EL | 1 |
| Gosnell, BA; Grace, M; Kneip, J; Levine, AS; Morley, JE | 1 |
| Han, JS; Xie, GX | 2 |
| Livingston, A; Morris, B | 1 |
| Pasternak, GW | 1 |
| Akkerman, AM; Bakel, HC; Büscher, H; Hill, RC; Maurer, R; Petcher, TJ; Römer, D; Welle, HB | 1 |
| Chang, KJ; Cuatrecasas, P; Hazum, E | 1 |
| Lajtha, A; Reith, ME; Sershen, H | 1 |
| Kosterlitz, HW; Paterson, SJ; Robson, LE | 1 |
| Lajtha, A; Reith, ME; Sershen, H; Vadasz, C | 1 |
| Fujino, M; Negishi, K; Oka, T; Sawa, A; Suda, M; Wakimasu, M | 1 |
| Herz, A; Shearman, GT | 1 |
| Harris, RA; Snell, D | 1 |
| Nishimura, S; Pasternak, GW; Wolozin, BL | 1 |
| Ishizuka, Y; Kajiwara, M; Matsumiya, T; Negishi, K; Oka, T; Watanabe, Y | 1 |
| Itzhak, Y; Keren, O; Sarne, Y | 1 |
| Nishimura, S; Pasternak, GW | 1 |
| Bearden, LJ; Snead, OC | 1 |
| Grace, M; Kniep, J; Levine, AS; Morley, JE | 1 |
| Hirst, M; Tepperman, FS | 1 |
| Brown, DR; Holtzman, SG; Locke, KW | 1 |
| Kandasamy, SB; Williams, BA | 1 |
| Cicero, TJ; Meyer, ER; Owens, DP; Schmoeker, PF | 1 |
| Johnson, N; Pasternak, GW | 1 |
| Martin, WR; Wu, KM | 1 |
| Tam, SW | 1 |
| Grace, M; Kneip, J; Levine, AS; Morley, JE; Zeugner, H | 1 |
| Boublik, JH; Clements, JA; Funder, JW; Herington, AC | 1 |
| Ahmed, MS | 1 |
| Kattau, RW; Leander, JD; Rathbun, RC | 1 |
| Code, RA; Tang, AH | 1 |
| Laurent, S; Schmitt, H | 1 |
| Levine, AS; Morley, JE | 1 |
| Dykstra, LA | 2 |
| Johnson, KM; Leventer, SM | 1 |
| Goldstein, A; Han, JS; Xie, GX | 1 |
| Herling, S; Solomon, RE; Valentino, RJ; Woods, JH | 1 |
| Aleman, DO; Carr, KD; Holland, MJ; Simon, EJ | 1 |
| Commissaris, RL; Henck, JW; Mokler, DJ; Rech, RH | 1 |
| Haertzen, CA; Henningfield, JE; Hickey, JE; Jasinski, DR; Johnson, RE; Kumor, K | 1 |
| Chaillet, P; Costentin, J; Marçais-Collado, H | 1 |
| Colpaert, FC; Janssen, PA | 1 |
| McCarthy, PS; Sanger, DJ | 1 |
| Dykstra, LA; Milar, KS | 1 |
| Herling, S; Woods, JH; Young, AM | 1 |
| Castañeda-Hernández, G; Flores-Murrieta, FJ; Granados-Soto, V; Hong, E; López-Muñoz, FJ | 1 |
| Fan, XT; Kitamura, K; Liu, XF; Oka, T; Taniguchi, T | 1 |
| Kromer, W | 1 |
| Barnard, EA; Benyhe, S; Borsodi, A; Simon, J; Wollemann, M | 1 |
| Barg, J; Nah, SY; Saya, D; Vogel, Z | 1 |
| Fan, SH; Ho, BT; Huo, YY; Levin, VA; Lu, JG; Meyers, CA; Payne, R; Tansey, LW | 1 |
| Lin, CE; Mello, NK; Negus, SS; Portoghese, PS | 1 |
| Hogenboom, F; Mulder, AH; Schoffelmeer, AN | 1 |
| Mello, NK; Negus, SS | 1 |
| Cheong, YP; Cho, KP; Kim, CJ; Kim, JK; Kim, KW; Kwun, J; Woo, RS | 1 |
1 review(s) available for ethylketocyclazocine and naloxone
| Article | Year |
|---|---|
Multiple opiate receptors for multiple opioid peptides.
Topics: Animals; beta-Endorphin; Brain; Cyclazocine; Dogs; Drug Tolerance; Dynorphins; Endorphins; Ethylketocyclazocine; Male; Mice; Morphine; Naloxone; Neuromuscular Junction; Phenazocine; Rabbits; Radioligand Assay; Rats; Receptors, Opioid; Synaptic Transmission | 1982 |
2 trial(s) available for ethylketocyclazocine and naloxone
| Article | Year |
|---|---|
Multidimensional scaling of subjective judgements of drug similarities among ketocyclazocine, morphine, cyclazocine, naloxone and placebo.
Topics: Adult; Cyclazocine; Ethylketocyclazocine; Generalization, Stimulus; Humans; Male; Models, Psychological; Morphine; Naloxone | 1990 |
The psychopharmacologic and prolactin response after large doses of naloxone in man.
Topics: Adult; Blood Pressure; Body Temperature; Cyclazocine; Discrimination, Psychological; Ethylketocyclazocine; Humans; Male; Models, Theoretical; Morphine; Naloxone; Prolactin; Pulse; Pupil; Respiration | 1988 |
187 other study(ies) available for ethylketocyclazocine and naloxone
| Article | Year |
|---|---|
Cloning and pharmacological characterization of a rat kappa opioid receptor.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Amino Acid Sequence; Analgesics; Animals; Benzeneacetamides; Cell Line; Cell Membrane; Cloning, Molecular; Corpus Striatum; Cyclic AMP; DNA Primers; DNA, Complementary; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Gene Library; In Situ Hybridization; Inositol 1,4,5-Trisphosphate; Kinetics; Ligands; Molecular Sequence Data; Pyrrolidines; Rats; Receptors, Opioid, kappa; Restriction Mapping; RNA, Messenger; Transfection | 1993 |
Cloning and functional comparison of kappa and delta opioid receptors from mouse brain.
Topics: Amino Acid Sequence; Animals; Base Sequence; Brain Chemistry; Cloning, Molecular; In Situ Hybridization; Mice; Molecular Sequence Data; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Somatostatin; RNA, Messenger; Sequence Homology, Amino Acid; Substrate Specificity; Tissue Distribution | 1993 |
Activation of the cloned human kappa opioid receptor by agonists enhances [35S]GTPgammaS binding to membranes: determination of potencies and efficacies of ligands.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenylate Cyclase Toxin; Animals; Binding Sites; Cell Membrane; CHO Cells; Cholera Toxin; Cloning, Molecular; Cricetinae; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Humans; Kinetics; Magnesium; Pertussis Toxin; Pyrrolidines; Receptors, Opioid, kappa; Recombinant Proteins; Sodium; Sulfur Radioisotopes; Virulence Factors, Bordetella | 1997 |
Adenosine 3':5'-cyclic monophosphate (cAMP) is not the mediator of kappa opiate effect on human placental lactogen release.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Cyclic AMP; Dose-Response Relationship, Drug; Ethylketocyclazocine; Female; Humans; Naloxone; Pertussis Toxin; Placenta; Placental Lactogen; Pregnancy; Receptors, Opioid; Receptors, Opioid, kappa; Virulence Factors, Bordetella | 1991 |
[Evaluation of the discriminative stimulus effect of an enkephalin analog, EK-399, in the rat].
Topics: Animals; Discrimination, Psychological; Enkephalins; Ethylketocyclazocine; Male; Morphine; Naloxone; Phenazocine; Rats; Rats, Inbred Strains; Receptors, Opioid | 1991 |
Reversal by naloxone of spinal antinociceptive effects of fentanyl, ketocyclazocine and midazolam.
Topics: Analgesia, Epidural; Animals; Catheters, Indwelling; Dose-Response Relationship, Drug; Drug Tolerance; Electric Stimulation; Ethylketocyclazocine; Fentanyl; Flumazenil; Injections, Spinal; Lumbar Vertebrae; Male; Midazolam; Naloxone; Nociceptors; Pain; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Opioid; Sensory Thresholds | 1991 |
Differential cross-tolerance to mu and kappa opioid agonists in morphine-tolerant rats responding under a schedule of food presentation.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzomorphans; Chlorpromazine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Tolerance; Ethylketocyclazocine; Fentanyl; Food; Male; Methadone; Morphine; Naloxone; Narcotics; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reinforcement Schedule | 1991 |
A monoclonal antibody recognizing kappa- but not mu- and delta-opioid receptors.
Topics: Animals; Antibodies, Monoclonal; Ascitic Fluid; Binding Sites; Brain; Cells, Cultured; Chick Embryo; Ethylketocyclazocine; Membranes; Naloxone; Neurons; Precipitin Tests; Rana esculenta; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa | 1991 |
Pharmacologic evidence for nociception resulting from noncontingent "rewarding" brain stimulation.
Topics: Analgesics, Opioid; Animals; Arousal; Cyclazocine; Dose-Response Relationship, Drug; Electric Stimulation; Escape Reaction; Ethylketocyclazocine; Hypothalamic Area, Lateral; Male; Medial Forebrain Bundle; Motivation; Naloxone; Nociceptors; Rats; Rats, Inbred F344; Receptors, Opioid; Sensory Thresholds | 1990 |
Effects of the opiate antagonists diprenorphine and naloxone and of selected opiate agonists on feeding behavior in guinea pigs.
Topics: Animals; Butorphanol; Circadian Rhythm; Cyclazocine; Diprenorphine; Ethylketocyclazocine; Feeding Behavior; Guinea Pigs; Morphinans; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1990 |
Opioid receptor ligands in the neonatal rat spinal cord: binding and in vitro depression of the nociceptive responses.
Topics: Animals; Animals, Newborn; Benzeneacetamides; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ethylketocyclazocine; In Vitro Techniques; Kinetics; Ligands; Morphine; Muscle, Smooth, Vascular; Naloxone; Narcotics; Nociceptors; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Spinal Cord | 1990 |
Discriminative stimulus properties of U50,488 and morphine: effects of training dose on stimulus substitution patterns produced by mu and kappa opioid agonists.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Benzomorphans; Cyclazocine; Discrimination Learning; Dose-Response Relationship, Drug; Ethylketocyclazocine; Fentanyl; Male; Methadone; Morphine; Naloxone; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1990 |
Characterization of kappa 1 and kappa 2 opioid binding sites in frog (Rana esculenta) brain membrane preparation.
Topics: Amino Acid Sequence; Animals; Brain; Ethylketocyclazocine; Female; In Vitro Techniques; Male; Membranes; Molecular Sequence Data; Naloxone; Rana esculenta; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Tritium | 1990 |
Effects of morphine, ethylketocyclazocine, N-allylnormetazocine and naloxone on locomotor activity in the rabbit.
Topics: Animals; Cyclazocine; Ethylketocyclazocine; Female; Male; Morphine; Motor Activity; Naloxone; Nictitating Membrane; Phenazocine; Rabbits | 1990 |
Enhanced sensitivity to behavioral effects of naltrexone in rats.
Topics: Animals; Conditioning, Psychological; Cyclazocine; Dose-Response Relationship, Drug; Ethylketocyclazocine; Male; Morphine; Naloxone; Naltrexone; Rats; Salivation | 1990 |
Withdrawal responses of guinea-pig isolated ileum following brief exposure to opiates and opioid peptides.
Topics: Animals; Benzomorphans; Buprenorphine; Cyclazocine; Endorphins; Ethylketocyclazocine; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Naloxone; Narcotics; Substance P; Substance Withdrawal Syndrome | 1986 |
Opioid binding properties of the purified kappa receptor from human placenta.
Topics: Benzomorphans; Binding, Competitive; Chromatography; Cyclazocine; Electrophoresis, Polyacrylamide Gel; Ethylketocyclazocine; Etorphine; Humans; Molecular Weight; Naloxone; Narcotics; Placenta; Radioligand Assay; Receptors, Opioid; Receptors, Opioid, kappa | 1989 |
Selective inhibitory effects of ethylketocyclazocine on reflex pathways to the external urethral sphincter of the cat.
Topics: Animals; Cats; Cyclazocine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Female; Morphine; Naloxone; Oligopeptides; Receptors, Opioid; Receptors, Opioid, kappa; Reflex; Urethra; Urinary Bladder; Urinary Incontinence | 1989 |
Central and peripheral opioid modulation of gastric relaxation induced by feeding in dogs.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzomorphans; Cyclazocine; Dogs; Dose-Response Relationship, Drug; Eating; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ethylketocyclazocine; Morphine; Muscle Relaxation; Naloxone; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Stomach; Vagotomy; Vagus Nerve | 1989 |
Kappa opiate receptor multiplicity: evidence for two U50,488-sensitive kappa 1 subtypes and a novel kappa 3 subtype.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Binding Sites; Cattle; Cerebellum; Cyclazocine; Edetic Acid; Ethylketocyclazocine; Guinea Pigs; In Vitro Techniques; Naloxone; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1989 |
Mu-opioid component of the ethylketocyclazocine (EKC) discriminative stimulus in the rat.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Cyclazocine; Discrimination, Psychological; Dose-Response Relationship, Drug; Ethylketocyclazocine; Fentanyl; Male; Morphine; Naloxone; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, mu | 1989 |
Discriminative stimulus effects of mu and kappa opioids in the pigeon: analysis of the effects of full and partial mu and kappa agonists.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzodiazepines; Benzomorphans; Columbidae; Cyclazocine; Discrimination Learning; Ethylketocyclazocine; Fentanyl; Morphinans; Naloxone; Narcotics; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1989 |
Failure of opioids to affect excitation and contraction in isolated ventricular heart muscle.
Topics: Acetylcholine; Action Potentials; Animals; Cyclazocine; Ethylketocyclazocine; Guinea Pigs; Humans; Morphine; Myocardial Contraction; Naloxone; Norepinephrine; Papillary Muscles; Rabbits; Synapses | 1989 |
Effects of ethylketocyclazocine on behaviors in mice using multi-dimensional behavioral analyses.
Topics: Analysis of Variance; Animals; Behavior, Animal; Cyclazocine; Dose-Response Relationship, Drug; Ethylketocyclazocine; Grooming; Male; Mice; Motor Activity; Naloxone; Receptors, Opioid; Receptors, Opioid, kappa; Time Factors | 1987 |
Opioid kappa-receptor agonists suppress sexual behaviors in male rough-skinned newts (Taricha granulosa).
Topics: Analgesics; Animals; Benzomorphans; Cyclazocine; Ethylketocyclazocine; Male; Morphinans; Morphine; Naloxone; Receptors, Opioid; Salamandridae; Sexual Behavior, Animal | 1987 |
Evaluation of the effects of opioid agonists and antagonists under a delayed matching-to-sample procedure in pigeons.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Columbidae; Cyclazocine; Discrimination Learning; Endorphins; Ethylketocyclazocine; Female; Methadone; Morphine; Naloxone; Phencyclidine; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Receptors, sigma | 1987 |
Relation of diltiazem binding sites to opioid receptor subtypes in the guinea-pig brain.
Topics: Animals; Binding, Competitive; Brain; Cyclazocine; Dihydromorphine; Diltiazem; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Guinea Pigs; Naloxone; Radioligand Assay; Receptors, Opioid | 1987 |
Role of opioid receptors in bombesin-induced grooming.
Topics: Animals; Benzodiazepines; Bombesin; Cyclazocine; Drug Tolerance; Ethylketocyclazocine; Grooming; Molecular Conformation; Naloxone; Narcotics; Receptors, Opioid | 1988 |
Opiate receptor subtypes in the nucleus tractus solitarii of the cat: the effect of vagal section.
Topics: Animals; Autoradiography; Cats; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ethylketocyclazocine; Female; Male; Medulla Oblongata; Naloxone; Receptors, Opioid; Vagotomy | 1988 |
Effects of opioid agonists and antagonists on oxytocin and vasopressin release in vitro.
Topics: Animals; Arginine Vasopressin; Benzomorphans; beta-Endorphin; Cyclazocine; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Male; Naloxone; Oxytocin; Peptide Fragments; Pituitary Gland, Posterior; Rats; Rats, Inbred Strains | 1985 |
Effects of 2% sodium chloride imbibition on various opiate related hyperphagic conditions.
Topics: Animals; Cyclazocine; Deoxyglucose; Dynorphins; Ethylketocyclazocine; Feeding Behavior; Insulin; Male; Naloxone; Narcotics; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium Chloride; Time Factors | 1985 |
An analysis of naltrexone and naloxone's possible agonistic actions in the dog.
Topics: Analgesics, Opioid; Animals; Cyclazocine; Dogs; Drug Synergism; Electroencephalography; Ethylketocyclazocine; Evoked Potentials; Female; Fentanyl; Morphine; Naloxone; Naltrexone; Reaction Time; Reflex; Reflex, Pupillary | 1985 |
Stereospecific opiate binding in living human polymorphonuclear leucocytes.
Topics: Analgesics, Opioid; Cyclazocine; Diprenorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Granulocytes; Humans; Kinetics; Naloxone; Neutrophils; Receptors, Opioid | 1985 |
Intrinsic activity and effects of guanyl-5'-yl imidodiphosphate, Gpp(NH)p and sodium ion on the affinity of dynorphin 1-13, nalorphine and nalorphine-7,8-oxide to kappa-opioid receptor.
Topics: Animals; Binding, Competitive; Brain; Cyclazocine; Dynorphins; Ethylketocyclazocine; Guanosine Triphosphate; Guanylyl Imidodiphosphate; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Muscle Contraction; Muscle, Smooth; Nalorphine; Naloxone; Peptide Fragments; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Sodium; Synaptosomes; Vas Deferens | 1985 |
On the opioid receptor subtype inhibiting the evoked release of 3H-noradrenaline from guinea-pig atria in vitro.
Topics: Animals; Atropine; Benzomorphans; Binding, Competitive; Corticosterone; Cyclazocine; Desipramine; Dynorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Etorphine; Guinea Pigs; Heart Atria; In Vitro Techniques; Morphine; Myocardium; Naloxone; Norepinephrine; Peptide Fragments; Phentolamine; Receptors, Opioid; Receptors, Opioid, kappa; Synapses | 1986 |
Presynaptic opioid receptors modulating acetylcholine release in the hippocampus of the rabbit.
Topics: Acetylcholine; Animals; Benzomorphans; Choline; Cyclazocine; Dose-Response Relationship, Drug; Dynorphins; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Hippocampus; Naloxone; Peptide Fragments; Rabbits; Receptors, Opioid; Receptors, Opioid, kappa; Synapses | 1986 |
Centrally-administered opioid selective agonists inhibit drinking in the rat.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Brain; Cyclazocine; Drinking Behavior; Dynorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ethylketocyclazocine; Male; Morphine; Naloxone; Peptide Fragments; Pyrrolidines; Rats; Receptors, Opioid | 1986 |
[Peripheral analgesic actions of opioid peptides and morphine analogues].
Topics: Analgesics, Opioid; Animals; Cyclazocine; Dynorphins; Enkephalin, Methionine; Ethylketocyclazocine; Levallorphan; Lidocaine; Male; Mice; Morphine; Naloxone; Pain; Peptide Fragments | 1986 |
Binaltorphimine and nor-binaltorphimine, potent and selective kappa-opioid receptor antagonists.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Chemical Phenomena; Chemistry; Cyclazocine; Dynorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Guinea Pigs; Male; Mice; Morphine; Naloxone; Naltrexone; Pyrrolidines; Rabbits; Receptors, Opioid; Receptors, Opioid, kappa | 1987 |
Involvement of opioid receptors in phencyclidine-induced enhancement of brain histamine turnover in mice.
Topics: Analgesics, Opioid; Animals; Brain; Cyclazocine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Haloperidol; Histamine; Histidine Decarboxylase; Ketamine; Male; Methylhistidines; Mice; Naloxone; Pargyline; Phenazocine; Phencyclidine; Receptors, Opioid | 1987 |
Opiates inhibit the discharges of fine afferent units from inflamed knee joint of the cat.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Arthritis; Cats; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Ethylketocyclazocine; Morphine; Naloxone; Nociceptors; Pain; Peripheral Nerves; Pyrrolidines | 1987 |
Effects of selective and non-selective kappa-opioid receptor agonists on cutaneous C-fibre-evoked responses of rat dorsal horn neurones.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Action Potentials; Animals; Cyclazocine; Dose-Response Relationship, Drug; Dynorphins; Electric Stimulation; Ethylketocyclazocine; Injections, Spinal; Male; Naloxone; Nerve Fibers; Pain; Peptide Fragments; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Skin; Spinal Cord; Time Factors | 1987 |
Effects of ethylketazocine and morphine alone and in combination with naloxone on schedule-controlled behavior in pigeons.
Topics: Analgesics, Opioid; Animals; Columbidae; Conditioning, Operant; Cyclazocine; Dose-Response Relationship, Drug; Drug Interactions; Ethylketocyclazocine; Male; Morphine; Naloxone; Reinforcement Schedule | 1987 |
Purification of a kappa-opioid receptor subtype from frog brain.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Brain Chemistry; Chromatography, Gel; Cyclazocine; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Membranes; Molecular Weight; Naloxone; Peptide Fragments; Pyrrolidines; Rana esculenta; Receptors, Opioid; Receptors, Opioid, kappa; Solubility | 1987 |
Inhibition of cardiac Na+, K+-ATPase activity by dynorphin-A and ethylketocyclazocine.
Topics: Adenosine Triphosphate; Animals; Cyclazocine; Dynorphins; Enzyme Activation; Ethylketocyclazocine; Male; Myocardium; Naloxone; Peptide Fragments; Potassium; Rats; Rats, Inbred Strains; Sodium; Sodium-Potassium-Exchanging ATPase | 1988 |
Peripheral antagonistic action of trimebutine and kappa opioid substances on acoustic stress-induced gastric motor inhibition in dogs.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acoustic Stimulation; Analgesics; Analgesics, Opioid; Animals; Benzoates; Benzomorphans; Cyclazocine; Dogs; Ethylketocyclazocine; Gastrointestinal Motility; Injections, Intravenous; Injections, Intraventricular; Naloxone; Narcotic Antagonists; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Stress, Psychological; Trimebutine | 1988 |
Effect of ethylketocyclazocine on acetylcholine release in guinea-pig brain slices.
Topics: Acetylcholine; Analgesics, Opioid; Animals; Brain; Cyclazocine; Ethylketocyclazocine; Guinea Pigs; In Vitro Techniques; Morphine; Naloxone | 1988 |
Peripheral and central antinociceptive actions of ethylketocyclazocine in the formalin test.
Topics: Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Cyclazocine; Ethylketocyclazocine; Formaldehyde; Injections, Intraventricular; Male; Naloxone; Pain; Rats | 1988 |
Characterization of human placental opioid receptors by 3H-ethylketocyclazocine and 3H-naloxone binding.
Topics: Analgesics, Opioid; Binding, Competitive; Cell Membrane; Cyclazocine; Ethylketocyclazocine; Female; Humans; Kinetics; Naloxone; Placenta; Pregnancy; Receptors, Opioid; Receptors, Opioid, kappa | 1988 |
Body temperature effects of opioids in rats: intracerebroventricular administration.
Topics: Animals; beta-Endorphin; Body Temperature; Cyclazocine; Dose-Response Relationship, Drug; Endorphins; Ethylketocyclazocine; Etorphine; Heroin; Injections, Intraventricular; Injections, Subcutaneous; Male; Morphine; Naloxone; Narcotics; Pentazocine; Phenazocine; Rats; Rats, Inbred Strains | 1986 |
Identification of multiple opiate receptors through neuroendocrine responses. II. Antagonism of mu, kappa and sigma agonists by naloxone and WIN 44,441-3.
Topics: Animals; Azocines; Corticosterone; Cyclazocine; Drug Interactions; Ethylketocyclazocine; Growth Hormone; Luteinizing Hormone; Male; Morphine; Naloxone; Narcotic Antagonists; Phenazocine; Pituitary Hormones, Anterior; Prolactin; Rats; Rats, Inbred Strains; Receptors, Opioid | 1985 |
The influence of opiate agonists on day-night feeding rhythms in young and old mice.
Topics: Aging; Animals; Cyclazocine; Endorphins; Ethylketocyclazocine; Feeding Behavior; Male; Mice; Morphine; Naloxone; Periodicity; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1985 |
TENA, a selective kappa opioid receptor antagonist.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Azocines; Benzomorphans; Cyclazocine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Guinea Pigs; Ileum; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Vas Deferens | 1985 |
Differentiating aspects of opioid receptor binding by [3H](-) (1R,5R,9R,2''S)-5,9-dimethyl-2-tetrahydrofurfuryl-2'-hydroxy-6,7- benzomorphan hydrochloride ([3H]Mr 2034), a drug preferentially acting on kappa-receptors.
Topics: Animals; Benzomorphans; Binding, Competitive; Cyclazocine; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; In Vitro Techniques; Kinetics; Male; Morphinans; Naloxone; Rats; Receptors, Opioid; Receptors, Opioid, kappa | 1985 |
Differentiating opioids by their pupillary effects in the rat.
Topics: Animals; Cyclazocine; Dose-Response Relationship, Drug; Ethylketocyclazocine; Male; Methadone; Motor Activity; Naloxone; Narcotics; Nystagmus, Physiologic; Phenazocine; Pupil; Rats; Rats, Inbred Strains; Receptors, Opioid; Stereoisomerism | 1985 |
Detection and characterization of four binding sites for opioids in the mouse brain.
Topics: Animals; Binding Sites; Brain Chemistry; Cyclazocine; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Models, Biological; Naloxone; Receptors, Opioid; Software; Tritium | 1985 |
Profile of activity of kappa receptor agonists in the rabbit vas deferens.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Benzodiazepines; Benzomorphans; Butorphanol; Cyclazocine; Ethylketocyclazocine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nalorphine; Naloxone; Pyrrolidines; Rabbits; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Vas Deferens | 1985 |
Plasma corticosterone changes in response to central or peripheral administration of kappa and sigma opiate agonists.
Topics: Animals; Brain; Corticosterone; Cyclazocine; Ethylketocyclazocine; Humans; Hypothalamo-Hypophyseal System; Male; Morphine; Naloxone; Naltrexone; Opioid-Related Disorders; Phenazocine; Pituitary-Adrenal System; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Receptors, sigma | 1985 |
The kappa opioid receptor and food intake.
Topics: Animals; Benzodiazepines; Benzomorphans; Butorphanol; Cyclazocine; Diprenorphine; Eating; Ethylketocyclazocine; Haloperidol; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Stereoisomerism; Time Factors | 1985 |
Opioid activity of lefetamine.
Topics: Anesthetics, Local; Animals; Binding, Competitive; Brain; Cyclazocine; Enkephalin, Methionine; Ethylketocyclazocine; Lethal Dose 50; Male; Methadone; Mice; Morphine; Naloxone; Phenethylamines; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Opioid | 1985 |
The pineal gland and opiate-induced feeding.
Topics: Animals; Butorphanol; Cyclazocine; Endorphins; Ethylketocyclazocine; Feeding Behavior; Male; Melatonin; Morphine; Naloxone; Pineal Gland; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa | 1985 |
Effects of opiate antagonists and putative kappa agonists on unpunished and punished operant behavior in the rat.
Topics: Animals; Conditioning, Operant; Cyclazocine; Diprenorphine; Ethylketocyclazocine; Male; Naloxone; Narcotic Antagonists; Punishment; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa | 1985 |
Involvement of different opioid receptor subtypes in electric shock-induced analgesia and motor suppression in the rat.
Topics: Animals; Cyclazocine; Electroshock; Enkephalin, Methionine; Ethylketocyclazocine; Male; Motor Activity; Naloxone; Pain; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, Opioid; Time Factors | 1985 |
Effects of tifluadom on food consumption compared with chlordiazepoxide and kappa agonists in the rat.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzodiazepines; Benzodiazepinones; Benzomorphans; Chlordiazepoxide; Convulsants; Cyclazocine; Drug Interactions; Eating; Ethylketocyclazocine; Flumazenil; Male; Naloxone; Pyrazoles; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, kappa | 1985 |
A monoclonal antibody capable of modulating opioid binding to rat neural membranes.
Topics: Animals; Antibodies, Monoclonal; Cell Line; Cyclazocine; Dihydromorphine; Diprenorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Flunitrazepam; Immunoglobulin M; Kinetics; Male; Mice; Mice, Inbred BALB C; Molecular Weight; Naloxone; Narcotics; Nerve Tissue; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Opioid | 1985 |
Voltage dependent changes in opiate inhibition of electrically-driven guinea pig ileum longitudinal muscle.
Topics: Animals; Cyclazocine; Electric Stimulation; Ethylketocyclazocine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine Derivatives; Muscle, Smooth; Naloxone; Narcotics; Receptors, Opioid | 1985 |
Classification of presynaptic opioid receptors in the rabbit ear artery by competitive antagonists.
Topics: Animals; Arteries; Benzomorphans; Binding, Competitive; Biological Assay; Cyclazocine; Ear; Enkephalin, Leucine; Ethylketocyclazocine; In Vitro Techniques; Naloxone; Rabbits; Receptors, Opioid; Synaptic Membranes | 1986 |
Agonist and antagonist actions of buprenorphine on three types of opioid receptor in isolated preparations.
Topics: Animals; Benzomorphans; Buprenorphine; Cyclazocine; Electric Stimulation; Ethylketocyclazocine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Morphinans; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Rabbits; Rats; Rats, Inbred Strains; Receptors, Opioid; Species Specificity; Time Factors; Vas Deferens | 1986 |
Discriminative stimulus effects of the opioid antagonist diprenorphine in the squirrel monkey.
Topics: Animals; Cyclazocine; Diprenorphine; Discrimination Learning; Dose-Response Relationship, Drug; Ethylketocyclazocine; Generalization, Stimulus; Morphinans; Naloxone; Narcotic Antagonists; Phenazocine; Psychotropic Drugs; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Saimiri | 1986 |
Conditioned suppression and opioid kappa receptor in mice.
Topics: Animals; Conditioning, Operant; Cyclazocine; Drug Tolerance; Ethylketocyclazocine; Male; Mice; Motor Activity; Naloxone; Narcotic Antagonists; Phencyclidine; Receptors, Opioid; Receptors, Opioid, kappa; Synaptic Membranes | 1986 |
Endogenous ligands for sigma opioid receptors in the brain ("sigmaphin"): evidence from binding assays.
Topics: Animals; Binding, Competitive; Brain; Chromatography, Gel; Cyclazocine; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Guinea Pigs; Kinetics; Male; Naloxone; Phenazocine; Phencyclidine; Radioligand Assay; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Receptors, Phencyclidine; Receptors, sigma | 1986 |
Sodium regulation of agonist binding at opioid receptors. I. Effects of sodium replacement on binding at mu- and delta-type receptors in 7315c and NG108-15 cells and cell membranes.
Topics: Adenylyl Cyclase Inhibitors; Animals; Cell Line; Cell Membrane; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Etorphine; Glioma; Guinea Pigs; Monensin; Naloxone; Neuroblastoma; Pituitary Neoplasms; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sodium | 1986 |
Studies of kappa agonist.
Topics: Animals; Brain; Cyclazocine; Enkephalin, Methionine; Enkephalins; Ethylketocyclazocine; Humans; Morphine; Naloxone; Receptors, Opioid; Receptors, Opioid, kappa | 1986 |
Prejunctional opioid receptors in the pulmonary artery of the rabbit.
Topics: Animals; Cyclazocine; Electric Stimulation; Ethylketocyclazocine; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Naloxone; Narcotics; Norepinephrine; Pulmonary Artery; Rabbits; Receptors, Opioid; Tetrodotoxin | 1986 |
Involvement of opioid receptors in hypo- and hyperthermic effects induced by phencyclidine in mice.
Topics: Animals; Benzomorphans; Body Temperature; Cyclazocine; Ethylketocyclazocine; Hyperthermia, Induced; Hypothermia, Induced; Male; Mice; Morphine; Naloxone; Narcotic Antagonists; Phenazocine; Phencyclidine; Receptors, Opioid | 1986 |
Reversible and irreversible binding of beta-funaltrexamine to mu, delta and kappa opioid receptors in guinea pig brain membranes.
Topics: Animals; Brain; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Ethylmaleimide; Guinea Pigs; Kinetics; Male; Membranes; Naloxone; Naltrexone; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sodium Chloride | 1986 |
A dose-ratio comparison of mu and kappa agonists in formalin and thermal pain.
Topics: Analgesia; Animals; Benzomorphans; Cyclazocine; Dose-Response Relationship, Drug; Ethylketocyclazocine; Fentanyl; Formaldehyde; Hot Temperature; Male; Naloxone; Pain; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sufentanil | 1986 |
Mutual interaction between presynaptic alpha 2-adrenoceptors and opioid kappa-receptors at the noradrenergic axons of rabbit brain cortex.
Topics: Animals; Axons; Cerebral Cortex; Clonidine; Cyclazocine; Ethylketocyclazocine; Female; Male; Naloxone; Norepinephrine; Rabbits; Receptors, Adrenergic, alpha; Receptors, Opioid; Yohimbine | 1986 |
Morphine- and ketocyclazocine-induced analgesia in the developing rat: differences due to type of noxious stimulus and body topography.
Topics: Age Factors; Analgesics; Animals; Animals, Suckling; Central Nervous System; Cyclazocine; Ethylketocyclazocine; Morphine; Naloxone; Pain; Pain Measurement; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1987 |
TRH-induced antinociception: interaction with the opioid systems?
Topics: Analgesia; Animals; Brain; Cyclazocine; Endorphins; Ethylketocyclazocine; Fentanyl; Male; Mice; Morphine; Naloxone; Receptors, Opioid; Thyrotropin-Releasing Hormone | 1987 |
Modulation of rat brain opioid receptors by cannabinoids.
Topics: Animals; Cannabinoids; Cyclazocine; Dihydromorphine; Dose-Response Relationship, Drug; Dronabinol; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ethylketocyclazocine; Etorphine; Male; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Spiperone | 1987 |
(+)- and (-)-N-allylnormetazocine binding sites in mouse brain: in vitro and in vivo characterization and regional distribution.
Topics: Animals; Binding, Competitive; Brain; Cyclazocine; Ethylketocyclazocine; Haloperidol; In Vitro Techniques; Mice; Naloxone; Phenazocine; Phencyclidine; Receptors, Opioid; Receptors, sigma; Stereoisomerism | 1987 |
Opiate receptor subtypes in the rat hypothalamus and neurointermediate lobe.
Topics: Animals; Binding, Competitive; Cyclazocine; Ethylketocyclazocine; Etorphine; Female; Hypothalamus; Kinetics; Naloxone; Phencyclidine; Pituitary Gland; Rats; Rats, Inbred Strains; Receptors, Opioid; Temperature | 1987 |
Opiates and medial hypothalamic knife cuts cause hyperphagia through different mechanisms.
Topics: Animals; Brain Mapping; Butorphanol; Cyclazocine; Dietary Carbohydrates; Dietary Fats; Eating; Ethylketocyclazocine; Hypothalamus, Middle; Male; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid | 1985 |
Characteristics of opioid receptors in guinea-pig cerebellum and human placenta.
Topics: Animals; Binding, Competitive; Cerebellum; Cyclazocine; Ethylketocyclazocine; Female; Guanylyl Imidodiphosphate; Guinea Pigs; Humans; In Vitro Techniques; Male; Naloxone; Placenta; Pregnancy; Receptors, Opioid; Receptors, Opioid, kappa; Sodium | 1986 |
Ethylketocyclazocine and N-cyclopropylmethyl-norazidomorphine are antagonists of morphine-induced analgesia in frog spinal cord.
Topics: Analgesia; Animals; Cyclazocine; Ethylketocyclazocine; Morphinans; Morphine; Naloxone; Narcotic Antagonists; Rana esculenta; Reflex; Spinal Cord | 1988 |
Effects of morphine, ethylketocyclazocine, U-50,488H and naloxone on the acquisition of a classically conditioned response in the rabbit.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Cerebellum; Conditioning, Classical; Cyclazocine; Dose-Response Relationship, Drug; Ethylketocyclazocine; Female; Male; Morphine; Naloxone; Pyrrolidines; Rabbits | 1987 |
Comparison of the discriminative stimulus properties of U50,488 and morphine in pigeons.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Columbidae; Cyclazocine; Dextroamphetamine; Discrimination Learning; Dose-Response Relationship, Drug; Ethylketocyclazocine; Female; Fentanyl; Methadone; Morphine; Naloxone; Phenazocine; Phencyclidine; Pyrrolidines; Time Factors | 1987 |
Effects of ethylketazocine and morphine on schedule-controlled behavior in pigeons and squirrel monkeys.
Topics: Animals; Columbidae; Conditioning, Operant; Cyclazocine; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Ethylketocyclazocine; Food; Male; Morphine; Naloxone; Saimiri; Time Factors | 1986 |
Opiate-induced turning in rats after injection into the ventral tegmental area.
Topics: Animals; Cyclazocine; Diprenorphine; Endorphins; Ethylketocyclazocine; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Stereotyped Behavior; Tegmentum Mesencephali | 1986 |
On the mechanisms of kappa-opioid-induced diuresis.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenal Medulla; Animals; Benzodiazepines; Catecholamines; Corticosterone; Cyclazocine; Diuresis; Ethylketocyclazocine; Male; Naloxone; Narcotics; Pyrrolidines; Rats; Sympatholytics | 1986 |
Effects of kappa opiate agonists, cholecystokinin and bombesin on intake of diets varying in carbohydrate-to-fat ratio in rats.
Topics: Animals; Body Weight; Bombesin; Butorphanol; Cyclazocine; Dietary Carbohydrates; Dietary Fats; Eating; Energy Intake; Ethylketocyclazocine; Food Preferences; Male; Naloxone; Rats; Rats, Inbred Strains; Sincalide | 1987 |
Evaluation of the effects of opioid agonists and antagonists under a fixed-consecutive-number schedule in rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzomorphans; Conditioning, Operant; Cyclazocine; Discrimination Learning; Ethylketocyclazocine; Male; Methadone; Morphine; Naloxone; Narcotics; Phenazocine; Pyrrolidines; Rats; Reinforcement Schedule | 1987 |
Selected opioids and responding for intracranial reinforcement.
Topics: Animals; Cyclazocine; Ethylketocyclazocine; Hypothalamic Area, Lateral; Naloxone; Phenazocine; Rats; Reinforcement, Psychology; Self Stimulation; Stereoisomerism | 1985 |
The occurrence of cross-tolerance between morphine and ethyl-ketocyclazocine using the tail-flick test: lack of effect of diazepam, phenobarbital, or amphetamine.
Topics: Amphetamine; Animals; Cyclazocine; Diazepam; Drug Interactions; Drug Tolerance; Ethylketocyclazocine; Male; Mice; Morphine; Naloxone; Phenobarbital; Time Factors | 1985 |
Behavioral effects of a novel kappa opioid analgesic, U-50488, in rats and rhesus monkeys.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Behavior, Animal; Cyclazocine; Discrimination, Psychological; Diuresis; Ethylketocyclazocine; Humans; Macaca mulatta; Male; Morphine; Naloxone; Pyrrolidines; Rats; Rats, Inbred Strains; Self Administration; Species Specificity; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors | 1985 |
Behavioral effects of selected opiates and phencyclidine in the nondependent and cyclazocine-dependent rhesus monkey.
Topics: Animals; Behavior, Animal; Cyclazocine; Dose-Response Relationship, Drug; Drug Tolerance; Ethylketocyclazocine; Food; Macaca mulatta; Male; Naloxone; Phenazocine; Phencyclidine; Stereoisomerism; Substance-Related Disorders | 1985 |
Food intake: opioid/purine interactions.
Topics: Animals; Butorphanol; Caffeine; Cyclazocine; Drug Interactions; Endorphins; Ethylketocyclazocine; Feeding Behavior; Male; Naloxone; Purines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa | 1984 |
Effects of a kappa receptor agonist, ethylketocyclazocine, on water consumption in water-deprived and nondeprived rats in diurnal and nocturnal tests.
Topics: Animals; Benzomorphans; Circadian Rhythm; Cyclazocine; Drinking Behavior; Ethylketocyclazocine; Male; Naloxone; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Water Deprivation | 1984 |
Kappa opiate receptor agonists: effects on behavior and on brain function and structure in rhesus monkeys.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Behavior, Animal; Benzomorphans; Brain; Computers; Cyclazocine; Dose-Response Relationship, Drug; Electroencephalography; Ethylketocyclazocine; Evoked Potentials; Macaca mulatta; Naloxone; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa | 1984 |
An in vivo pharmacological analysis of benzomorphan binding sites in rats.
Topics: Animals; Benzomorphans; Bombesin; Brain; Cyclazocine; Dose-Response Relationship, Drug; Ethylketocyclazocine; Grooming; Humans; Male; Morphinans; Morphine; Naloxone; Narcotics; Phenazocine; Rats; Rats, Inbred Strains; Receptors, Opioid; Stereoisomerism; Stereotyped Behavior | 1984 |
Kappa opioid agonists and antagonists: effects on drinking and urinary output.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzodiazepines; Benzomorphans; Butorphanol; Clonidine; Cyclazocine; Drinking; Ethylketocyclazocine; Naloxone; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Urination; Vasopressins | 1984 |
Comparative antagonism by naltrexone and naloxone of mu, kappa, and delta agonists.
Topics: Animals; Cyclazocine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Vas Deferens | 1984 |
Differential inhibition by propranolol of feeding induced in rats by various stimuli.
Topics: Animals; Cyclazocine; Deoxyglucose; Dose-Response Relationship, Drug; Eating; Ethylketocyclazocine; Insulin; Male; Naloxone; Propranolol; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa | 1984 |
Ethylketocyclazocine decreases noradrenaline release and blood pressure in the rabbit at a peripheral opioid receptor.
Topics: Animals; Blood Pressure; Cyclazocine; Decerebrate State; Electric Stimulation; Ethylketocyclazocine; Female; Heart Rate; Hemodynamics; Male; Naloxone; Norepinephrine; Rabbits; Receptors, Opioid | 1984 |
Lesions of the globus pallidus and striatum attenuate ketocyclazocine-induced feeding.
Topics: Animals; Brain Mapping; Corpus Striatum; Cyclazocine; Endorphins; Ethylketocyclazocine; Feeding Behavior; Globus Pallidus; Male; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa | 1984 |
Kappa-opiates and urination: pharmacological evidence for an endogenous role of the kappa-opiate receptor in fluid and electrolyte balance.
Topics: Animals; Azocines; Benzomorphans; Cyclazocine; Diuresis; Ethylketocyclazocine; Female; Injections, Intraperitoneal; Morphinans; Morphine; Naloxone; Potassium; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium; Water-Electrolyte Balance | 1984 |
Radioligands for probing opioid receptors.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzomorphans; Binding Sites; Brain; Cyclazocine; Diprenorphine; Enkephalin, Leucine; Enkephalins; Ethylketocyclazocine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Naloxone; Pro-Opiomelanocortin; Protein Precursors; Pyrrolidines; Radioligand Assay; Rats; Receptors, Opioid; Vas Deferens | 1984 |
Characterization of prototypical opioid antagonists, agonist-antagonists, and agonists in the morphine-dependent rhesus monkey.
Topics: Animals; Buprenorphine; Cyclazocine; Ethylketocyclazocine; Humans; Macaca mulatta; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Receptors, Opioid; Receptors, Opioid, mu; Substance Withdrawal Syndrome | 1984 |
Peripheral opioid receptors located on the rat saphenous nerve.
Topics: Animals; Cyclazocine; Ethylketocyclazocine; Lidocaine; Male; Morphine; Naloxone; Peripheral Nerves; Rats; Rats, Inbred Strains; Receptors, Opioid; Vasodilation | 1984 |
EEG and behavioral effects of ethylketocyclazocine, morphine and cyclazocine in rats: differential sensitivities towards naloxone.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Cyclazocine; Electroencephalography; Ethylketocyclazocine; Male; Morphine; Naloxone; Rats | 1980 |
Dynorphin is a specific endogenous ligand of the kappa opioid receptor.
Topics: Analgesics, Opioid; Animals; Binding, Competitive; Brain; Cyclazocine; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalins; Ethylketocyclazocine; Guinea Pigs; In Vitro Techniques; Ligands; Morphine Derivatives; Myenteric Plexus; Naloxone; Peptide Fragments; Receptors, Opioid | 1982 |
Kappa opioid properties of dynorphin and its peptide fragments on the guinea-pig Ileum.
Topics: Animals; Cyclazocine; Drug Interactions; Drug Tolerance; Dynorphins; Endorphins; Ethylketocyclazocine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Naloxone; Peptide Fragments; Receptors, Opioid; Receptors, Opioid, kappa | 1982 |
On the criteria for classifying opiate agonists in rats.
Topics: Analgesics; Animals; Charcoal; Cyclazocine; Ethylketocyclazocine; Gastrointestinal Motility; Male; Morphine; Naloxone; Narcotics; Rats; Rats, Inbred Strains | 1982 |
In vivo evidence for multiple opiate receptors mediating analgesia in the rat spinal cord.
Topics: Animals; Cyclazocine; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Injections, Spinal; Male; Naloxone; Pain; Phenazocine; Rats; Rats, Inbred Strains; Receptors, Opioid; Spinal Cord | 1982 |
Potency of three opiate antagonists to reverse the inhibitory activity of dynorphin, enkephalins and opioid-like alkaloids on the guinea pig ileum.
Topics: Animals; Azocines; Benzomorphans; Cyclazocine; Dynorphins; Endorphins; Enkephalins; Ethylketocyclazocine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine Derivatives; Muscle, Smooth; Naloxone; Narcotic Antagonists | 1982 |
Effects of ketazocine, ethylketazocine and phenazocine on schedule-controlled behavior: antagonism by naloxone.
Topics: Analgesics, Opioid; Animals; Columbidae; Conditioning, Psychological; Cyclazocine; Dose-Response Relationship, Drug; Ethylketocyclazocine; Male; Naloxone; Phenazocine | 1982 |
Differential modification of opiate receptor activity by arylsulfatase treatment.
Topics: Analgesia; Analgesics, Opioid; Animals; Arylsulfatases; beta-Endorphin; Cyclazocine; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Drug Antagonism; Endorphins; Enkephalin, Methionine; Enkephalins; Ethylketocyclazocine; Hormones; Kinetics; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Receptors, Opioid; Sulfatases | 1983 |
Further study of kappa opioids on increased urination.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzomorphans; Cyclazocine; Diuresis; Ethylketocyclazocine; Male; Morphinans; Naloxone; Narcotic Antagonists; Narcotics; Piperidines; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Urination | 1983 |
Possible medullary kappa hyperalgesic mechanism. I. A new potential role for endogenous opioid peptides in pain perception.
Topics: Animals; Cyclazocine; Dogs; Dynorphins; Endorphins; Ethylketocyclazocine; Medulla Oblongata; Naloxone; Pain; Receptors, Opioid; Reflex | 1983 |
Dynorphin inhibition of the neurotensin contractile activity on the myenteric plexus.
Topics: Animals; Atropine; Cyclazocine; Dose-Response Relationship, Drug; Drug Tolerance; Dynorphins; Endorphins; Ethylketocyclazocine; Guinea Pigs; Ileum; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Naloxone; Nerve Tissue Proteins; Neurotensin; Peptide Fragments; Receptors, Opioid; Tetrodotoxin | 1984 |
The effect of two different buffers on the high affinity 3H-ethylketocyclazocine and 3H-SKF10047 binding to guinea pig brain membranes.
Topics: Analgesics, Opioid; Animals; Brain; Cyclazocine; Ethylketocyclazocine; Guinea Pigs; HEPES; In Vitro Techniques; Morphine; Naloxone; Phenazocine; Piperazines; Receptors, Opioid; Tritium; Tromethamine | 1984 |
In vivo evidence for benzomorphan-selective receptors in rats.
Topics: Analgesics, Opioid; Animals; Benzomorphans; Bombesin; Buprenorphine; Cyclazocine; Dose-Response Relationship, Drug; Drug Tolerance; Ethylketocyclazocine; Male; Morphinans; Morphine; Naloxone; Phenazocine; Pruritus; Rats; Rats, Inbred Strains; Receptors, Opioid | 1984 |
Dynorphin A: inhibitory effect on other opiate ligand bindings in the mouse brain.
Topics: Animals; Brain; Cyclazocine; Dynorphins; Endorphins; Ethylketocyclazocine; In Vitro Techniques; Ligands; Male; Mice; Mice, Inbred ICR; Naloxone; Narcotics; Peptide Fragments; Receptors, Opioid; Sodium Chloride | 1984 |
Feeding systems in Chinese hamsters.
Topics: Animals; Brain; Calcitonin; Circadian Rhythm; Cricetinae; Cyclazocine; Diabetes Mellitus; Dynorphins; Eating; Endorphins; Ethylketocyclazocine; Feeding Behavior; Haloperidol; Mesocricetus; Naloxone; Peptide Fragments; Phenazocine; Sincalide; Starvation | 1984 |
Cardiac slowing induced by peripheral kappa-opiate receptor stimulation in rats.
Topics: Adrenergic beta-Antagonists; Animals; Benzomorphans; Cyclazocine; Electrocardiography; Ethylketocyclazocine; Heart Rate; Hemodynamics; Injections, Intravenous; Male; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Time Factors; Vagotomy | 1984 |
Opioid receptor agonists in the rabbit colon: comparison of in vivo and in vitro studies.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Colon; Cyclazocine; Dynorphins; Electric Conductivity; Enkephalins; Ethylketocyclazocine; Fentanyl; Male; Morphine; Naloxone; Narcotics; Pyrrolidines; Rabbits; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1984 |
Dynorphin-(1-13) restores the potency of morphine on the tolerant guinea pig ileum.
Topics: Animals; beta-Endorphin; Cyclazocine; Drug Interactions; Drug Tolerance; Dynorphins; Endorphins; Enkephalin, Leucine; Ethylketocyclazocine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Peptide Fragments | 1984 |
The effect of ovariectomy, estradiol and progesterone on opioid modulation of feeding.
Topics: Animals; Appetite Regulation; Brain; Castration; Cyclazocine; Dynorphins; Eating; Estradiol; Ethylketocyclazocine; Female; Naloxone; Progesterone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa | 1984 |
[Dynorphin: analgesic effect via kappa receptors in the spinal cord of rats].
Topics: Analgesics; Animals; Cyclazocine; Dynorphins; Ethylketocyclazocine; Female; Naloxone; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Spinal Cord | 1984 |
Binding of [3H]clonidine to membranes from cow neurohypophysis and cerebral cortex of the rat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Cattle; Cerebral Cortex; Clonidine; Cyclazocine; Enkephalin, Leucine; Ethylketocyclazocine; In Vitro Techniques; Kinetics; Male; Membranes; Morphine; Naloxone; Narcotics; Pituitary Gland, Posterior; Rats | 1984 |
[Dynorphin: analgesic effect via kappa receptors in spinal cord of the spinal cords of rats].
Topics: Analgesics; Animals; Cyclazocine; Dynorphins; Ethylketocyclazocine; Female; Morphine; Naloxone; Pain; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Sensory Thresholds; Spinal Cord | 1984 |
Multiple opiate receptors: [3H]ethylketocyclazocine receptor binding and ketocyclazocine analgesia.
Topics: Analgesics; Animals; Brain; Cyclazocine; Dihydromorphine; Dose-Response Relationship, Drug; Enkephalin, Methionine; Enkephalins; Ethylketocyclazocine; In Vitro Techniques; Mice; Morphine; Motor Activity; Naloxone; Rats; Receptors, Opioid; Receptors, Opioid, kappa | 1980 |
Bremazocine: a potent, long-acting opiate kappa-agonist.
Topics: Analgesia; Animals; Benzomorphans; Brain; Cyclazocine; Electric Stimulation; Ethylketocyclazocine; Guinea Pigs; Ileum; Macaca mulatta; Male; Mice; Morphinans; Morphine; Naloxone; Pentazocine; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Vas Deferens | 1980 |
Possible role of distinct morphine and enkephalin receptors in mediating actins of benzomorphan drugs (putative kappa and sigma agonists).
Topics: Animals; Benzomorphans; Brain; Cyclazocine; Diprenorphine; Endorphins; Enkephalins; Ethylketocyclazocine; Guanosine Triphosphate; Morphinans; Morphine; Naloxone; Neuroblastoma; Rats; Receptors, Opioid; Sodium; Synaptic Membranes | 1980 |
Endogenous peptide(s) inhibiting [3H]cocaine binding in mouse brain.
Topics: Animals; Binding Sites; Cell Membrane; Cerebral Cortex; Cocaine; Cyclazocine; Dihydromorphine; Dioxanes; Ethylketocyclazocine; Mice; Molecular Weight; Naloxone; Peptides; Receptors, Opioid; Spiperone | 1980 |
Characterization of the kappa-subtype of the opiate receptor in the guinea-pig brain.
Topics: Animals; Benzomorphans; Binding Sites; Binding, Competitive; Brain; Cyclazocine; Dihydromorphine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Guinea Pigs; Naloxone; Naltrexone; Narcotics; Phenoxybenzamine; Receptors, Opioid | 1981 |
Strain differences in opiate receptors in mouse brain.
Topics: Animals; Brain; Cyclazocine; Dihydromorphine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Naloxone; Receptors, Opioid; Species Specificity | 1981 |
Evidence that dynorphin-(1-13) acts as an agonist on opioid kappa-receptors.
Topics: Animals; Cyclazocine; Dynorphins; Electric Stimulation; Endorphins; Ethylketocyclazocine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Muscle Contraction; Muscle, Smooth; Naloxone; Peptide Fragments; Rabbits; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Vas Deferens | 1982 |
D-Ala2,D-Leu5-enkephalin generalizes to a discriminative stimulus produced by fentanyl but not ethylketocyclazocine.
Topics: Animals; Cyclazocine; Discrimination, Psychological; Endorphins; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Fentanyl; Generalization, Stimulus; Male; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid | 1982 |
Interactions between narcotic agonists, partial agonists andd antagonists evaluated by punished an unpunished behavior in the rat.
Topics: Animals; Conditioning, Psychological; Cyclazocine; Dose-Response Relationship, Drug; Ethylketocyclazocine; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Phenazocine; Punishment; Rats; Rats, Inbred Strains; Receptors, Opioid | 1982 |
The binding of kappa- and sigma-opiates in rat brain.
Topics: Animals; Binding Sites; Brain; Culture Techniques; Cyclazocine; Dihydromorphine; Enkephalins; Ethylketocyclazocine; Ligands; Male; Naloxone; Narcotics; Phenazocine; Rats; Rats, Inbred Strains; Receptors, Opioid; Tritium | 1982 |
The choice of opiate receptor subtype by neo-endorphins.
Topics: Animals; Benzomorphans; beta-Endorphin; Cyclazocine; Drug Interactions; Endorphins; Enkephalins; Ethylketocyclazocine; Guinea Pigs; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Naloxone; Protein Precursors; Rabbits; Receptors, Opioid | 1982 |
Differential effect of humoral endorphin on the binding of opiate agonists and antagonists.
Topics: Animals; Binding Sites; Binding, Competitive; Cyclazocine; Endorphins; Enkephalins; Ethylketocyclazocine; In Vitro Techniques; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Receptors, Opioid; Sodium | 1982 |
Opiate and opioid peptide binding in rat goldfish: further evidence for opiate receptor heterogeneity.
Topics: Animals; Brain; Cyclazocine; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Goldfish; Male; Naloxone; Narcotics; Phenazocine; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Receptors, sigma | 1982 |
The epileptogenic spectrum of opiate agonists.
Topics: Animals; Anticonvulsants; beta-Endorphin; Cyclazocine; Electroencephalography; Endorphins; Enkephalin, Leucine; Epilepsy; Ethylketocyclazocine; Injections, Intraventricular; Male; Naloxone; Narcotics; Phenazocine; Rats; Rats, Inbred Strains | 1982 |
An investigation of the role of kappa opiate receptor agonists in the initiation of feeding.
Topics: Animals; Circadian Rhythm; Cyclazocine; Eating; Ethylketocyclazocine; Male; Morphine; Naloxone; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Starvation; Time Factors | 1982 |
Concerning the specificity of the hypothalamic opiate receptor responsible for food intake in the rat.
Topics: Animals; Body Temperature Regulation; Codeine; Cyclazocine; Dextrorphan; Eating; Ethylketocyclazocine; Levorphanol; Male; Morphine; Naloxone; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Ventromedial Hypothalamic Nucleus | 1982 |
Effects of opiate antagonists and putative mu- and kappa-agonists on milk intake in rat and squirrel monkey.
Topics: Animals; Buprenorphine; Cyclazocine; Diazepam; Diprenorphine; Drinking; Ethylketocyclazocine; Etorphine; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Saimiri; Taste | 1982 |
Peptide and non-peptide opioid-induced hyperthermia in rabbits.
Topics: Animals; beta-Endorphin; Body Temperature; Cyclazocine; Endorphins; Enkephalin, Methionine; Enkephalins; Ethylketocyclazocine; Male; Morphine; Naloxone; Peptides; Phenazocine; Rats | 1983 |
[3H]Mr 2034 labels a high affinity opioid kappa-receptor not accessible to naloxazone.
Topics: Animals; Benzomorphans; Binding, Competitive; Brain; Cyclazocine; Ethylketocyclazocine; In Vitro Techniques; Kinetics; Morphinans; Naloxone; Rats; Receptors, Opioid; Receptors, Opioid, kappa | 1983 |
Opiate-induced enhancement of the effects of naloxone on serum luteinizing hormone levels in the male rat: specificity for Mu agonists.
Topics: Animals; Binding, Competitive; Cyclazocine; Ethanol; Ethylketocyclazocine; Kinetics; Luteinizing Hormone; Male; Morphine; Naloxone; Pentobarbital; Phenazocine; Rats; Rats, Inbred Strains; Receptors, Opioid | 1983 |
The binding to rat brain homogenates of Mr2034, a universal opiate.
Topics: Animals; Benzomorphans; Brain; Cyclazocine; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Male; Morphinans; Naloxone; Phenazocine; Rats; Rats, Inbred Strains; Receptors, Opioid | 1983 |
An analysis of nicotinic and opioid processes in the medulla oblongata and nucleus ambiguus of the dog.
Topics: Animals; Blood Pressure; Cyclazocine; Decerebrate State; Dogs; Electric Stimulation; Endorphins; Ethylketocyclazocine; Female; Fentanyl; Heart Rate; Male; Mecamylamine; Medulla Oblongata; Naloxone; Nicotine; Phenazocine; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Receptors, sigma | 1983 |
Naloxone-inaccessible sigma receptor in rat central nervous system.
Topics: Animals; Binding, Competitive; Brain; Cyclazocine; Enkephalins; Ethylketocyclazocine; Kinetics; Naloxone; Phenazocine; Phencyclidine; Rats; Receptors, Opioid; Receptors, sigma; Spinal Cord; Tissue Distribution | 1983 |
The effect of the opioid-benzodiazepine, tifluadom, on ingestive behaviors.
Topics: Animals; Benzodiazepines; Butorphanol; Cyclazocine; Drinking Behavior; Ethylketocyclazocine; Feeding Behavior; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa | 1983 |
Opiate binding sites in bovine adrenal medulla.
Topics: Adrenal Medulla; Animals; Binding Sites; Brain; Brain Chemistry; Cattle; Cyclazocine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; In Vitro Techniques; Ligands; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid | 1983 |
Characterization of solubilized opiate receptors from human placenta.
Topics: Binding, Competitive; Chemical Phenomena; Chemistry, Physical; Cyclazocine; Ethylketocyclazocine; Etorphine; Female; Humans; Naloxone; Placenta; Pregnancy; Receptors, Opioid; Solubility | 1983 |
N-allylnormetazocine (SKF-10,047): the induction of feeding by a putative sigma agonist.
Topics: Animals; Cyclazocine; Dose-Response Relationship, Drug; Drug Interactions; Eating; Ethylketocyclazocine; Male; Morphine; Naloxone; Phenazocine; Rats; Rats, Inbred Strains; Receptors, Opioid | 1983 |
Effects of mu- and kappa-opioid receptor agonists on urinary output in mice.
Topics: Animals; Benzomorphans; Cyclazocine; Dose-Response Relationship, Drug; Ethylketocyclazocine; Fentanyl; Male; Mice; Morphine; Naloxone; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Species Specificity; Stimulation, Chemical; Urination | 1983 |
Discriminative stimulus properties of nalorphine in the rhesus monkeys.
Topics: Animals; Benzodiazepines; Benzomorphans; Conditioning, Operant; Cyclazocine; Discrimination Learning; Dose-Response Relationship, Drug; Ethylketocyclazocine; Macaca mulatta; Male; Nalorphine; Naloxone; Phenazocine; Receptors, Opioid; Receptors, Opioid, kappa | 1983 |
Central cardiovascular effects of kappa agonists dynorphin-(1-13) and ethylketocyclazocine in the anaesthetized rat.
Topics: Animals; beta-Endorphin; Blood Pressure; Cyclazocine; Dynorphins; Endorphins; Enkephalin, Methionine; Ethylketocyclazocine; Fentanyl; Heart Rate; Male; Naloxone; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Vagus Nerve | 1983 |
Adrenal modulation of opiate induced feeding.
Topics: Adrenal Glands; Adrenalectomy; Animals; Butorphanol; Corticosterone; Cyclazocine; Endorphins; Ethylketocyclazocine; Feeding Behavior; Male; Naloxone; Rats; Rats, Inbred Strains | 1983 |
Effects of ketocyclazocine and ethylketocyclazocine on electric shock titration.
Topics: Animals; Behavior, Animal; Cyclazocine; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Electroshock; Ethylketocyclazocine; Morphine; Naloxone; Saimiri | 1983 |
Phencyclidine-induced inhibition of striatal acetylcholine release: comparisons with mu, kappa, and sigma opiate agonists.
Topics: Acetylcholine; Animals; Corpus Striatum; Cyclazocine; Ethylketocyclazocine; Haloperidol; Male; Morphine; Naloxone; Narcotic Antagonists; Phenazocine; Phencyclidine; Rats; Rats, Inbred Strains | 1984 |
Analgesia induced by intrathecal injection of dynorphin B in the rat.
Topics: Analgesics; Animals; Cyclazocine; Dose-Response Relationship, Drug; Drug Tolerance; Dynorphins; Endorphins; Enkephalin, Leucine; Ethylketocyclazocine; Female; Injections, Spinal; Morphine; Naloxone; Rats | 1984 |
Narcotic discrimination in pigeons: antagonism by naltrexone.
Topics: Animals; Columbidae; Cyclazocine; Discrimination, Psychological; Dose-Response Relationship, Drug; Ethylketocyclazocine; Meperidine; Morphine; Naloxone; Naltrexone; Narcotics | 1984 |
Analgesic effects of ethylketocyclazocine and morphine in rat and toad.
Topics: Analgesia; Animals; Brain; Bufo marinus; Cyclazocine; Dose-Response Relationship, Drug; Electroshock; Ethylketocyclazocine; Male; Morphine; Motor Activity; Naloxone; Rats; Rats, Inbred Strains | 1984 |
Behavioral interactions of opioid agonists and antagonists with serotonergic systems.
Topics: Animals; Brain; Conditioning, Operant; Cyclazocine; DOM 2,5-Dimethoxy-4-Methylamphetamine; Dose-Response Relationship, Drug; Ethylketocyclazocine; Lysergic Acid Diethylamide; Male; Metergoline; Naloxone; Narcotic Antagonists; Narcotics; Phenazocine; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Reinforcement Schedule | 1984 |
Progress report from the NIDA Addiction Research Center Baltimore, Maryland (1984).
Topics: Blood Pressure; Body Temperature; Compulsive Behavior; Cyclazocine; Discrimination Learning; Endorphins; Ethylketocyclazocine; Euphoria; Gambling; Glucose; Heart Rate; Humans; Morphine; Naloxone; Nicotine; Perception; Respiration; Substance-Related Disorders; Time Factors | 1984 |
Development of enhanced sensitivity to naloxone.
Topics: Animals; Buprenorphine; Cyclazocine; Diprenorphine; Dose-Response Relationship, Drug; Drug Interactions; Ethylketocyclazocine; Male; Meperidine; Naloxone; Phencyclidine; Reaction Time; Saimiri | 1983 |
Catatonic or hypotonic immobility induced in mice by intracerebroventricular injection of mu or kappa opioid receptor agonists as well as enkephalins or inhibitors of their degradation.
Topics: Animals; Benzomorphans; Catatonia; Cyclazocine; Enkephalins; Ethylketocyclazocine; Fentanyl; Humans; Immobilization; Injections, Intraventricular; Male; Mice; Morphine; Naloxone; Narcotic Antagonists; Narcotics | 1983 |
Agonist and antagonist effects of prototype opiate drugs in rats discriminating fentanyl from saline: characteristics of partial generalization.
Topics: Animals; Conditioning, Operant; Cyclazocine; Discrimination Learning; Ethylketocyclazocine; Fentanyl; Male; Morphine; Nalorphine; Naloxone; Narcotics; Phenazocine; Rats; Rats, Inbred Strains; Sodium Chloride | 1984 |
Increased food and water intake produced in rats by opiate receptor agonists.
Topics: Animals; Cyclazocine; Drinking; Drug Interactions; Eating; Enkephalins; Ethylketocyclazocine; Male; Morphine; Naloxone; Narcotics; Rats | 1981 |
Effects of ketocyclazocine alone and in combination with naloxone on schedule-controlled responding in squirrel monkeys.
Topics: Animals; Conditioning, Operant; Cyclazocine; Dose-Response Relationship, Drug; Ethylketocyclazocine; Male; Naloxone; Reinforcement Schedule; Saimiri | 1983 |
Classification of narcotics on the basis of their reinforcing, discriminative, and antagonist effects in rhesus monkeys.
Topics: Animals; Behavior, Animal; Conditioning, Operant; Cyclazocine; Discrimination, Psychological; Ethylketocyclazocine; Humans; Macaca; Macaca mulatta; Morphine; Naloxone; Naltrexone; Narcotics; Opioid-Related Disorders; Reinforcement, Psychology; Self Administration | 1982 |
Evidence against the participation of mu- and kappa-opioid receptors in the analgesic activity of ketorolac in rats.
Topics: Analgesics; Analgesics, Non-Narcotic; Animals; Ethylketocyclazocine; Female; Ketorolac; Morphine; Movement Disorders; Naloxone; Pain Measurement; Rats; Rats, Wistar; Receptors, Opioid, kappa; Receptors, Opioid, mu; Time Factors; Tolmetin | 1995 |
The modulation of placental lactogen release by opioids: a role for extracellular calcium.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenylate Cyclase Toxin; Analgesics; Calcium; Cells, Cultured; Dopamine; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Ethylketocyclazocine; Gene Expression Regulation; Humans; Ionomycin; Naloxone; Naltrexone; Narcotics; Pertussis Toxin; Placental Lactogen; Pyrrolidines; Time Factors; Trophoblasts; Virulence Factors, Bordetella | 1993 |
A method to estimate the potency of the mu-component of an opioid having mixed mu-, and kappa- and/or delta-agonist activities.
Topics: Animals; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Female; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Postural Balance; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reflex | 1995 |
Unexpected prosecretory action component of loperamide at mu-opioid receptors in the guinea-pig colonic mucosa in vitro.
Topics: Alprostadil; Amino Acid Sequence; Animals; Chlorides; Colon; Dose-Response Relationship, Drug; Ethylketocyclazocine; Guinea Pigs; Intestinal Mucosa; Loperamide; Male; Molecular Sequence Data; Naloxone; Naltrexone; Patch-Clamp Techniques; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin; Theophylline | 1995 |
[3H]dynorphin1-8 binding sites in frog (Rana esculenta) brain membranes.
Topics: Amino Acid Sequence; Animals; Brain; Cell Membrane; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Ethylketocyclazocine; Guanylyl Imidodiphosphate; Molecular Sequence Data; Naloxone; Peptide Fragments; Rana esculenta; Receptors, Opioid; Sodium Chloride; Tritium | 1994 |
Opiate receptor agonists regulate phosphorylation of synapsin I in cocultures of rat spinal cord and dorsal root ganglion.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Cell Communication; Cells, Cultured; Colforsin; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Ganglia, Spinal; Isoproterenol; Kinetics; Male; Morphine; Naloxone; Neurons; Phosphates; Phosphoproteins; Phosphorylation; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid; Serotonin; Spinal Cord; Synapsins; Synaptosomes | 1993 |
The opioid mechanism of interferon-alpha action.
Topics: Animals; Dextroamphetamine; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Drug Synergism; Ethylketocyclazocine; Extinction, Psychological; Generalization, Psychological; Interferon-alpha; Male; Naloxone; Rats; Rats, Wistar; Receptors, Opioid | 1994 |
Effects of kappa opioids on cocaine self-administration by rhesus monkeys.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Circadian Rhythm; Cocaine; Dose-Response Relationship, Drug; Ethylketocyclazocine; Female; Macaca mulatta; Male; Naloxone; Naltrexone; Pyrrolidines; Receptors, Opioid, kappa; Self Administration; Substance-Related Disorders | 1997 |
Kappa1- and kappa2-opioid receptors mediating presynaptic inhibition of dopamine and acetylcholine release in rat neostriatum.
Topics: Acetylcholine; Animals; Benzeneacetamides; Dopamine; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ethylketocyclazocine; In Vitro Techniques; Male; N-Methylaspartate; Naloxone; Neostriatum; Neural Inhibition; Peptide Fragments; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1997 |
Effects of kappa opioid agonists on the discriminative stimulus effects of cocaine in rhesus monkeys.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Cocaine; Discrimination Learning; Discrimination, Psychological; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Ethylketocyclazocine; Macaca mulatta; Male; Naloxone; Narcotic Antagonists; Receptors, Opioid, kappa; Salicylamides | 1999 |
Receptor selectivity of Met-enkephalin-Arg6-Phe7, an endogenous opioid peptide, in cerebral cortex of human and rat.
Topics: Adult; Animals; Benzeneacetamides; Benzomorphans; Binding Sites; Cerebral Cortex; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Ethylketocyclazocine; Female; Humans; Male; Naloxone; Naltrexone; Norepinephrine; Oligopeptides; Peptide Fragments; Peptides; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin | 2000 |