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ethylketocyclazocine and enkephalin, ala(2)-mephe(4)-gly(5)-

ethylketocyclazocine has been researched along with enkephalin, ala(2)-mephe(4)-gly(5)- in 60 studies

Research

Studies (60)

Timeframe	Studies, this research(%)	All Research%
pre-1990	35 (58.33)	18.7374
1990's	21 (35.00)	18.2507
2000's	4 (6.67)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Akil, H; Goldstein, A; Mansour, A; Meng, F; Thompson, RC; Watson, SJ; Xie, GX	1
Gannon, RL; Terrian, DM	1
Besse, D; Besson, JM; Lombard, MC	1
Bhargava, HN; Gulati, A	1
Gudehithlu, KP; McDonald, JS; Rattan, AK; Tejwani, GA	1
Duckles, SP; Li, YJ	1
Benyhe, S; Borsodi, A; Varga, E; Wollemann, M	1
Bettaney, J; Dray, A; James, IF; Ketchum, SB; Perkins, MN	1
Hanissian, SH; Tejwani, GA	1
Magnan, J; Tiberi, M	1
Besse, D; Besson, JM; Lombard, MC; Roques, BP; Zajac, JM	1
Fedynyshyn, JP; Kwiat, G; Lee, NM	1
Bueno, L; Gué, M; Junien, JL	1
Brantl, V; Liebmann, C; Schrader, U	1
Bhargava, HN; Gulati, A; Ramarao, P	2
Bhargava, HN; Ramarao, P	1
Frey, EA; Jacobson, AE; Rice, KC; Tocque, B	1
Burks, TF; Fox, DA	1
Bertelli, GM; Borea, PA; Gilli, G	1
Cicero, TJ; Nock, B; O'Connor, LH; Rajpara, A	1
Ho, BY; Naeseth, JS; Portoghese, PS; Takemori, AE	1
Dougall, IG; Leff, P	1
Dashwood, MR; Muddle, JR; Spyer, KM	1
Geppert, M; Illes, P; Jackisch, R	1
Brenner, AS; Geppert, M; Illes, P; Jackisch, R	1
Kirby, GC; McQueen, DS	1
Russell, NJ; Schaible, HG; Schmidt, RF	1
Benyhe, S; Borsodi, A; Hepp, J; Khan, A; Medzihradszky, K; Simon, J; Szücs, M; Wollemann, M	1
Belisle, S; Bellabarba, D; Gallo-Payet, N; Lehoux, JG; Lemaire, S; Petit, A	1
Alvinerie, M; Bueno, L; Gue, M; Honde, C; Junien, JL; Pascaud, X	1
Goodman, SR; McLaughlin, PJ; Zagon, IS	1
Coscia, CJ; Roth, BL; Spain, JW	1
Benyhe, S; Borsodi, A; Simon, J; Szücs, M; Wollemann, M	1
Brown, SR; Cox, BM; Werling, LL; Zarr, GD	2
Bunn, SJ; Hanley, MR; Wilkin, GP	1
Itzhak, Y; Pasternak, GW	1
Glasel, JA; Myers, WE	1
Faden, AI; Krumins, SA	1
Brown, SR; Cote, TE; Cox, BM; Puttfarcken, P; Werling, LL	1
Brown, SR; Cox, BM; Puttfarcken, P; Werling, LL	1
Liu-Chen, LY; Tam, SW	1
Krumins, SA	1
Delay-Goyet, P; Roques, BP; Zajac, JM	1
Burkard, WP; Flück, N; Müller, PM	1
Bélisle, S; Bellabarba, D; Gallo-Payet, N; Lehoux, JG; Petit, A	1
Castanas, E; Gravanis, A; Hatzoglou, A; Margioris, AN; Zoumakis, E	1
Fukuda, K; Kato, S; Mori, K	1
Barnard, EA; Benyhe, S; Borsodi, A; Simon, J; Wollemann, M	1
Cotter, P; Deviche, P; Gulledge, CC	1
Bhargava, HN; Reddy, PL	1
Bakogeorgou, E; Castanas, E; Hatzoglou, A	1
Akil, H; Fine, JL; Hoversten, MT; Mansour, A; Mosberg, HI; Taylor, LP; Thompson, RC; Watson, SJ	1
Hogenboom, F; Mulder, AH; Schoffelmeer, AN	1
Castanas, E; Denizot, A; Dermitzaki, I; Gravanis, A; Hatzoglou, A; Henry, JF; Kampa, M; Margioris, AN; Oliver, C	1
Cheong, YP; Cho, KP; Kim, CJ; Kim, JK; Kim, KW; Kwun, J; Woo, RS	1
Bartolini, A; Bianchi, E; Bracci, L; Galeotti, N; Ghelardini, C; Guarna, M; Neri, C; Sonetti, D; Stefano, G	1
Castanas, E; Kampa, M; Kouroumalis, E; Nifli, AP; Notas, G; Papasava, D; Thermos, K; Xidakis, K	1
Benaderet, TS; Bishop-Mathis, K; Dersch, CM; Partilla, JS; Prisinzano, TE; Rothman, RB; Simpson, DS; Wang, X; Xu, H	1

Other Studies

60 other study(ies) available for ethylketocyclazocine and enkephalin, ala(2)-mephe(4)-gly(5)-

Article	Year
Cloning and pharmacological characterization of a rat kappa opioid receptor. Proceedings of the National Academy of Sciences of the United States of America, 1993, Nov-01, Volume: 90, Issue:21 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Amino Acid Sequence; Analgesics; Animals; Benzeneacetamides; Cell Line; Cell Membrane; Cloning, Molecular; Corpus Striatum; Cyclic AMP; DNA Primers; DNA, Complementary; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Gene Library; In Situ Hybridization; Inositol 1,4,5-Trisphosphate; Kinetics; Ligands; Molecular Sequence Data; Pyrrolidines; Rats; Receptors, Opioid, kappa; Restriction Mapping; RNA, Messenger; Transfection	1993
Kappa opioid agonists inhibit transmitter release from guinea pig hippocampal mossy fiber synaptosomes. Neurochemical research, 1992, Volume: 17, Issue:8 Topics: Animals; Azocines; Calcium; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ethylketocyclazocine; Glutamates; Glutamic Acid; Guinea Pigs; Hippocampus; Male; Potassium; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Synaptosomes	1992
Autoradiographic distribution of mu, delta and kappa opioid binding sites in the superficial dorsal horn, over the rostrocaudal axis of the rat spinal cord. Brain research, 1991, May-10, Volume: 548, Issue:1-2 Topics: Animals; Autoradiography; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Ethylketocyclazocine; Kinetics; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord; Tritium	1991
The effect of morphine tolerance-dependence and abstinence on mu, delta, and kappa opiate receptors of discrete brain regions and spinal cord of the rat. NIDA research monograph, 1990, Volume: 105 Topics: Animals; Brain Chemistry; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Ethylketocyclazocine; In Vitro Techniques; Male; Morphine; Morphine Dependence; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord; Substance Withdrawal Syndrome	1990
Modulation of mu, kappa and delta opioid receptors in the rat brain by isoflurane and enflurane. Neuropharmacology, 1991, Volume: 30, Issue:6 Topics: Analgesics; Animals; Brain Chemistry; Cerebral Cortex; Enflurane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Ethylketocyclazocine; In Vitro Techniques; Isoflurane; Male; Mesencephalon; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord	1991
Differential effects of neuropeptide Y and opioids on neurogenic responses of the perfused rat mesentery. European journal of pharmacology, 1991, Apr-03, Volume: 195, Issue:3 Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ethylketocyclazocine; Guanethidine; In Vitro Techniques; Male; Methoxamine; Muscle, Smooth, Vascular; Narcotics; Neuropeptide Y; Rats; Rats, Inbred Strains; Splanchnic Circulation; Vasoconstriction; Vasodilation	1991
The occurrence of different kappa opioid receptors (K1 and K2) in frog (Rana esculenta) brain membranes. Acta physiologica Hungarica, 1990, Volume: 76, Issue:4 Topics: Animals; Binding Sites; Binding, Competitive; Brain; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Ligands; Morphinans; Rana esculenta; Receptors, Opioid; Receptors, Opioid, kappa	1990
Opioid receptor ligands in the neonatal rat spinal cord: binding and in vitro depression of the nociceptive responses. British journal of pharmacology, 1990, Volume: 99, Issue:3 Topics: Animals; Animals, Newborn; Benzeneacetamides; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ethylketocyclazocine; In Vitro Techniques; Kinetics; Ligands; Morphine; Muscle, Smooth, Vascular; Naloxone; Narcotics; Nociceptors; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Spinal Cord	1990
Modulation of mu, delta and kappa opioid receptors in rat brain by metal ions and histidine. Neuropharmacology, 1990, Volume: 29, Issue:5 Topics: Animals; Brain Chemistry; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Ethylketocyclazocine; Histidine; Kinetics; Male; Membranes; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sulfhydryl Reagents; Trace Elements; Zinc	1990
Demonstration of the heterogeneity of the kappa-opioid receptors in guinea-pig cerebellum using selective and nonselective drugs. European journal of pharmacology, 1990, Jun-12, Volume: 188, Issue:6 Topics: Animals; Benzeneacetamides; Benzomorphans; Binding, Competitive; Cerebellum; Computers; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ethylketocyclazocine; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Membranes; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu	1990
Pre- and postsynaptic distribution of mu, delta and kappa opioid receptors in the superficial layers of the cervical dorsal horn of the rat spinal cord. Brain research, 1990, Jun-25, Volume: 521, Issue:1-2 Topics: Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Ethylketocyclazocine; Male; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord	1990
Characterization of high affinity opioid binding sites in rat periaqueductal gray P2 membrane. European journal of pharmacology, 1989, Jan-02, Volume: 159, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ethylketocyclazocine; In Vitro Techniques; Male; Membranes; Periaqueductal Gray; Pyrrolidines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Opioid	1989
Central and peripheral opioid modulation of gastric relaxation induced by feeding in dogs. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 250, Issue:3 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzomorphans; Cyclazocine; Dogs; Dose-Response Relationship, Drug; Eating; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ethylketocyclazocine; Morphine; Muscle Relaxation; Naloxone; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Stomach; Vagotomy; Vagus Nerve	1989
Opioid receptor affinities of the blood-derived tetrapeptides hemorphin and cytochrophin. European journal of pharmacology, 1989, Aug-03, Volume: 166, Issue:3 Topics: Animals; Brain Chemistry; Cyclazocine; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Female; Guinea Pigs; Hemoglobins; In Vitro Techniques; Male; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu	1989
Changes in multiple opioid receptors in regions of the brain in rats treated chronically with thyroxine. Neuropharmacology, 1989, Volume: 28, Issue:9 Topics: Animals; Blood Pressure; Body Weight; Brain; Chromatography, High Pressure Liquid; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Ethylketocyclazocine; Heart Rate; Hyperthyroidism; Male; Membranes; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Thyroxine	1989
Antagonism of kappa opioid mediated effects in the rat by cyclo(Leu-Gly). Life sciences, 1989, Volume: 45, Issue:26 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Cerebral Cortex; Cyclazocine; Diuresis; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Male; Neuropeptides; Peptides, Cyclic; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Spinal Cord	1989
The mu-opioid receptor in the 7315c tumor cell. European journal of pharmacology, 1987, Nov-03, Volume: 143, Issue:1 Topics: Cell Membrane; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; Ethylketocyclazocine; Oligopeptides; Receptors, Opioid; Receptors, Opioid, mu; Tumor Cells, Cultured	1987
Roles of central and peripheral mu, delta and kappa opioid receptors in the mediation of gastric acid secretory effects in the rat. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 244, Issue:2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Brain; Cyclazocine; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ethylketocyclazocine; Gastric Acid; Male; Morphine; Naltrexone; Pyrrolidines; Quaternary Ammonium Compounds; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu	1988
Temperature dependence of the binding of mu, delta and kappa agonists to the opiate receptors in guinea-pig brain. European journal of pharmacology, 1988, Feb-09, Volume: 146, Issue:2-3 Topics: Animals; Brain; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Guinea Pigs; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Temperature	1988
[3H]U-69593 labels a subtype of kappa opiate receptor with characteristics different from that labeled by [3H]ethylketocyclazocine. Life sciences, 1988, Volume: 42, Issue:23 Topics: Animals; Benzeneacetamides; Binding, Competitive; Brain; Cell Membrane; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Male; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Sodium Chloride; Temperature; Tritium	1988
Nor-binaltorphimine, a highly selective kappa-opioid antagonist in analgesic and receptor binding assays. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Animals; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Guinea Pigs; Male; Mice; Morphine; Naltrexone; Oligopeptides; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa	1988
Estimation of opioid receptor agonist dissociation constants with beta-chlornaltrexamine, an irreversible ligand which also displays agonism. British journal of pharmacology, 1988, Volume: 95, Issue:1 Topics: Animals; Cyclazocine; Drug Interactions; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Ethylketocyclazocine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphinans; Muscle, Smooth; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu	1988
Opiate receptor subtypes in the nucleus tractus solitarii of the cat: the effect of vagal section. European journal of pharmacology, 1988, Oct-11, Volume: 155, Issue:1-2 Topics: Animals; Autoradiography; Cats; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ethylketocyclazocine; Female; Male; Medulla Oblongata; Naloxone; Receptors, Opioid; Vagotomy	1988
Effect of methimazole-induced hypothyroidism on multiple opioid receptors in rat brain regions. Pharmacology, 1988, Volume: 37, Issue:6 Topics: Animals; Body Temperature; Body Weight; Brain Chemistry; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Ethylketocyclazocine; Heart Rate; Hypothyroidism; Male; Methimazole; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Triiodothyronine	1988
Characterization of opioid receptors modulating noradrenaline release in the hippocampus of the rabbit. Journal of neurochemistry, 1986, Volume: 46, Issue:6 Topics: Animals; Benzomorphans; Clonidine; Cyclazocine; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Ethylketocyclazocine; Hippocampus; Morphine; Norepinephrine; Rabbits; Receptors, Opioid	1986
Presynaptic opioid receptors modulating acetylcholine release in the hippocampus of the rabbit. Naunyn-Schmiedeberg's archives of pharmacology, 1986, Volume: 332, Issue:2 Topics: Acetylcholine; Animals; Benzomorphans; Choline; Cyclazocine; Dose-Response Relationship, Drug; Dynorphins; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Hippocampus; Naloxone; Peptide Fragments; Rabbits; Receptors, Opioid; Receptors, Opioid, kappa; Synapses	1986
Characterization of opioid receptors in the cat carotid body involved in chemosensory depression in vivo. British journal of pharmacology, 1986, Volume: 88, Issue:4 Topics: Animals; Carotid Body; Cats; Chemoreceptor Cells; Cyclazocine; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Ethylketocyclazocine; Hypercapnia; Hypoxia; Peptide Fragments; Receptors, Opioid	1986
Opiates inhibit the discharges of fine afferent units from inflamed knee joint of the cat. Neuroscience letters, 1987, Apr-23, Volume: 76, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Arthritis; Cats; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Ethylketocyclazocine; Morphine; Naloxone; Nociceptors; Pain; Peripheral Nerves; Pyrrolidines	1987
Purification of a kappa-opioid receptor subtype from frog brain. Neuropeptides, 1987, Volume: 10, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Brain Chemistry; Chromatography, Gel; Cyclazocine; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Membranes; Molecular Weight; Naloxone; Peptide Fragments; Pyrrolidines; Rana esculenta; Receptors, Opioid; Receptors, Opioid, kappa; Solubility	1987
Functional opioid receptor sites in human placentas. The Journal of clinical endocrinology and metabolism, 1988, Volume: 66, Issue:2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Cyclazocine; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Ethylketocyclazocine; Gonadotropin-Releasing Hormone; Humans; Kinetics; Placenta; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Thyrotropin-Releasing Hormone	1988
CNS blockade of acoustic stress-induced gastric motor inhibition by kappa-opiate agonists in dogs. The American journal of physiology, 1988, Volume: 254, Issue:6 Pt 1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acoustic Stimulation; Adrenocorticotropic Hormone; Analgesics; Animals; Cyclazocine; Dogs; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Ethylketocyclazocine; Gastrointestinal Motility; Hydrocortisone; Pyrrolidines; Stress, Physiological	1988
Characterization of opioid binding sites in murine neuroblastoma. Brain research, 1988, May-24, Volume: 449, Issue:1-2 Topics: Analgesics, Opioid; Animals; Binding, Competitive; Cell Line; Clone Cells; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Kinetics; Ligands; Mice; Neuroblastoma; Receptors, Opioid	1988
Differential ontogeny of multiple opioid receptors (mu, delta, and kappa). The Journal of neuroscience : the official journal of the Society for Neuroscience, 1985, Volume: 5, Issue:3 Topics: Animals; Animals, Newborn; Brain; Computers; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tritium	1985
Separation of kappa-opioid receptor subtype from frog brain. FEBS letters, 1985, Apr-22, Volume: 183, Issue:2 Topics: Animals; Brain Chemistry; Centrifugation, Density Gradient; Chromatography, Gel; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; Ethylketocyclazocine; Rana esculenta; Receptors, Opioid; Receptors, Opioid, kappa	1985
Opioid binding to rat and guinea-pig neural membranes in the presence of physiological cations at 37 degrees C. The Journal of pharmacology and experimental therapeutics, 1985, Volume: 233, Issue:3 Topics: Animals; Brain; Cations; Cyclazocine; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Guanosine Triphosphate; Guinea Pigs; In Vitro Techniques; Male; Narcotics; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Temperature; Tritium	1985
Evidence for a kappa-opioid receptor on pituitary astrocytes: an autoradiographic study. Neuroscience letters, 1985, Apr-19, Volume: 55, Issue:3 Topics: Animals; Astrocytes; Autoradiography; Binding Sites; Binding, Competitive; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Etorphine; Pituitary Gland; Rats; Receptors, Opioid; Receptors, Opioid, kappa	1985
Kappa-opiate binding to rat brain and guinea pig cerebellum: sensitivity towards ions and nucleotides. Neuroscience letters, 1986, Feb-14, Volume: 64, Issue:1 Topics: Animals; Brain; Cerebellum; Cyclazocine; Electrolytes; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Guanine Nucleotides; Guinea Pigs; Rats; Receptors, Opioid; Receptors, Opioid, kappa	1986
Subclass specificity of anti-idiotypic anti-opiate receptor antibodies in rat brain, guinea pig cerebellum, & neuroblastoma x glioma (NG 108-15). Life sciences, 1986, May-12, Volume: 38, Issue:19 Topics: Animals; Antibodies, Anti-Idiotypic; Binding, Competitive; Cell Line; Cerebellum; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Guinea Pigs; Morphine; Neurilemma; Neurons; Rats; Receptors, Opioid	1986
Traumatic injury alters opiate receptor binding in rat spinal cord. Annals of neurology, 1986, Volume: 19, Issue:5 Topics: Animals; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Male; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord; Spinal Cord Injuries	1986
Sodium regulation of agonist binding at opioid receptors. I. Effects of sodium replacement on binding at mu- and delta-type receptors in 7315c and NG108-15 cells and cell membranes. Molecular pharmacology, 1986, Volume: 30, Issue:2 Topics: Adenylyl Cyclase Inhibitors; Animals; Cell Line; Cell Membrane; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Etorphine; Glioma; Guinea Pigs; Monensin; Naloxone; Neuroblastoma; Pituitary Neoplasms; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sodium	1986
Sodium regulation of agonist binding at opioid receptors. II. Effects of sodium replacement on opioid binding in guinea pig cortical membranes. Molecular pharmacology, 1986, Volume: 30, Issue:2 Topics: Animals; Cell Membrane; Cerebral Cortex; Cyclazocine; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Etorphine; Guinea Pigs; Male; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sodium	1986
Opioid ligand binding sites in the spinal cord of the guinea-pig. Neuropharmacology, 1986, Volume: 25, Issue:5 Topics: Animals; Binding, Competitive; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Membranes; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord	1986
Reversible and irreversible binding of beta-funaltrexamine to mu, delta and kappa opioid receptors in guinea pig brain membranes. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:2 Topics: Animals; Brain; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Ethylmaleimide; Guinea Pigs; Kinetics; Male; Membranes; Naloxone; Naltrexone; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sodium Chloride	1986
Opioid receptor binding in rat spinal cord. Neurochemical research, 1987, Volume: 12, Issue:3 Topics: Animals; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Ligands; Male; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord	1987
Differences of binding characteristics of non-selective opiates towards mu and delta receptor types. Life sciences, 1987, Aug-10, Volume: 41, Issue:6 Topics: Animals; Binding, Competitive; Brain; Cell Membrane; Cerebellum; Cyclazocine; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Ethylketocyclazocine; Etorphine; Male; Oligopeptides; Rabbits; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu	1987
Characteristics of 3H-tifluadom binding in guinea-pig brain membranes. Journal of receptor research, 1984, Volume: 4, Issue:1-6 Topics: Animals; Benzodiazepines; Benzomorphans; Binding Sites; Brain; Cyclazocine; Dihydromorphine; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Guinea Pigs; In Vitro Techniques; Male; Morphine; Receptors, Opioid	1984
The modulation of placental lactogen release by opioids: a role for extracellular calcium. Molecular and cellular endocrinology, 1993, Volume: 90, Issue:2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenylate Cyclase Toxin; Analgesics; Calcium; Cells, Cultured; Dopamine; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Ethylketocyclazocine; Gene Expression Regulation; Humans; Ionomycin; Naloxone; Naltrexone; Narcotics; Pertussis Toxin; Placental Lactogen; Pyrrolidines; Time Factors; Trophoblasts; Virulence Factors, Bordetella	1993
Identification and characterization of opioid-binding sites present in the Ishikawa human endometrial adenocarcinoma cell line. The Journal of clinical endocrinology and metabolism, 1995, Volume: 80, Issue:2 Topics: Acids; Adenocarcinoma; Binding Sites; Endometrial Neoplasms; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Female; Humans; Narcotics; Tumor Cells, Cultured	1995
Location of regions of the opioid receptor involved in selective agonist binding. The Journal of biological chemistry, 1995, Mar-24, Volume: 270, Issue:12 Topics: Animals; Binding Sites; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ethylketocyclazocine; Narcotics; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Recombinant Fusion Proteins	1995
[3H]dynorphin1-8 binding sites in frog (Rana esculenta) brain membranes. Neuropeptides, 1994, Volume: 26, Issue:5 Topics: Amino Acid Sequence; Animals; Brain; Cell Membrane; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Ethylketocyclazocine; Guanylyl Imidodiphosphate; Molecular Sequence Data; Naloxone; Peptide Fragments; Rana esculenta; Receptors, Opioid; Sodium Chloride; Tritium	1994
Identification, partial characterization, and hypothalamic distribution of kappa, mu, and delta opioid receptors in a passerine songbird (Junco hyemalis). Brain research, 1993, Jun-18, Volume: 614, Issue:1-2 Topics: Animals; Autoradiography; Binding, Competitive; Birds; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ethylketocyclazocine; Feeding Behavior; Hypothalamic Area, Lateral; Hypothalamus; In Vitro Techniques; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Thermodynamics; Ventromedial Hypothalamic Nucleus	1993
Effect of low pH treatment on opioid peptides binding to their receptors and functional coupling of G-proteins to adenylyl cyclase in the rat spinal cord. Peptides, 1996, Volume: 17, Issue:4 Topics: Adenylyl Cyclases; Analgesics; Animals; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Ethylketocyclazocine; GTP-Binding Proteins; Hydrogen-Ion Concentration; Kinetics; Male; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sodium Fluoride; Spinal Cord	1996
The antiproliferative effect of opioid receptor agonists on the T47D human breast cancer cell line, is partially mediated through opioid receptors. European journal of pharmacology, 1996, Jan-25, Volume: 296, Issue:2 Topics: Adenocarcinoma; Amino Acid Sequence; Binding Sites; Breast Neoplasms; Cell Division; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Etorphine; Humans; Molecular Sequence Data; Morphine; Narcotic Antagonists; Opioid Peptides; Receptors, Opioid; Tumor Cells, Cultured	1996
Key residues defining the mu-opioid receptor binding pocket: a site-directed mutagenesis study. Journal of neurochemistry, 1997, Volume: 68, Issue:1 Topics: Animals; Binding, Competitive; COS Cells; Drug Residues; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Ethylketocyclazocine; Immunohistochemistry; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Rats; Receptors, Opioid, mu	1997
Kappa1- and kappa2-opioid receptors mediating presynaptic inhibition of dopamine and acetylcholine release in rat neostriatum. British journal of pharmacology, 1997, Volume: 122, Issue:3 Topics: Acetylcholine; Animals; Benzeneacetamides; Dopamine; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ethylketocyclazocine; In Vitro Techniques; Male; N-Methylaspartate; Naloxone; Neostriatum; Neural Inhibition; Peptide Fragments; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu	1997
Kappa1-opioid binding sites are the dominant opioid binding sites in surgical specimens of human pheochromocytomas and in a human pheochromocytoma (KAT45) cell line. European journal of pharmacology, 1999, Jan-08, Volume: 364, Issue:2-3 Topics: Analgesics, Opioid; Binding Sites; Binding, Competitive; Catecholamines; Cell Membrane; Diprenorphine; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Epinephrine; Ethylketocyclazocine; Humans; Narcotic Antagonists; Norepinephrine; Opioid Peptides; Pheochromocytoma; Radioligand Assay; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tritium; Tumor Cells, Cultured	1999
Receptor selectivity of Met-enkephalin-Arg6-Phe7, an endogenous opioid peptide, in cerebral cortex of human and rat. Life sciences, 2000, May-26, Volume: 67, Issue:1 Topics: Adult; Animals; Benzeneacetamides; Benzomorphans; Binding Sites; Cerebral Cortex; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Ethylketocyclazocine; Female; Humans; Male; Naloxone; Naltrexone; Norepinephrine; Oligopeptides; Peptide Fragments; Peptides; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin	2000
Endogenous morphine modulates acute thermonociception in mice. Journal of neurochemistry, 2002, Volume: 80, Issue:2 Topics: Acute Disease; Analgesics, Opioid; Animals; Buffers; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Ethylketocyclazocine; Gas Chromatography-Mass Spectrometry; Hyperalgesia; Immunoglobulin G; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Morphine; Motor Activity; Nociceptors; Opioid Peptides; Skin Temperature	2002
The inhibitory effect of opioids on HepG2 cells is mediated via interaction with somatostatin receptors. European journal of pharmacology, 2007, Jan-19, Volume: 555, Issue:1 Topics: Analgesics, Opioid; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Humans; Narcotic Antagonists; Octreotide; Receptors, Opioid; Receptors, Somatostatin; RNA, Messenger; Somatostatin	2007
Differential effects of opioid agonists on G protein expression in CHO cells expressing cloned human opioid receptors. Brain research bulletin, 2008, Sep-05, Volume: 77, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Benzamides; Blotting, Western; CHO Cells; Cricetinae; Cricetulus; Diterpenes, Clerodane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Etorphine; Female; Furans; Gene Expression; GTP-Binding Protein alpha Subunits, G12-G13; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Morphine; Oligopeptides; Piperazines; Pyrones; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu	2008