ethylisopropylamiloride has been researched along with amiloride in 568 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 49 (8.63) | 18.7374 |
| 1990's | 277 (48.77) | 18.2507 |
| 2000's | 164 (28.87) | 29.6817 |
| 2010's | 75 (13.20) | 24.3611 |
| 2020's | 3 (0.53) | 2.80 |
| Authors | Studies |
|---|---|
| Cala, PM; King, SA; Nygaard, EB; Pedersen, SF; Rigor, RR | 1 |
| Balkovetz, DF; Takaichi, K; Wang, D; Warnock, DG | 1 |
| Clément, O; Pucéat, M; Scamps, F; Terzic, A; Vassort, G | 1 |
| Montrose, MH; Murer, H; Zimolo, Z | 1 |
| Guerra, L; Helmle-Kolb, C; Murer, H; Vilella, S | 1 |
| Bolard, J; Cybulska, B; Czerwinski, A; Henry-Toulme, N; Seksek, O | 1 |
| Blair, IA; Cragoe, EJ; Limbird, LE; Prakash, C; Wilson, AL; Womble, SW | 1 |
| Inariba, H; Inoue, T; Kanayama, Y; Negoro, N; Takaori, K; Takeda, T | 1 |
| Barber, DL; Ganz, MB | 1 |
| Albus, U; Lang, HJ; Linz, W; Martorana, P; Schölkens, BA; Scholz, W | 1 |
| Horvat, B; Salihagić, A; Taheri, S | 1 |
| Capogrossi, MC; Carbonin, P; Gambassi, G | 1 |
| Casavola, V; Guerra, L; Helmle-Kolb, C; Murer, H; Reshkin, SJ | 1 |
| Andreeva, N; Cragoe, E; Khodorov, B; Sokolova, S; Stelmashook, E; Victorov, I | 1 |
| Camps, M; Furriols, M; Gumà, A; Muñoz, P; Palacín, M; Testar, X; Zorzano, A | 1 |
| Allen, JC; Bishara, M; Cragoe, EJ; Kahn, AM; McCarty, NA; Navran, SS; O'Neil, RG; Seidel, CL; Shelat, H | 1 |
| Cragoe, EJ; Gu, H; Momma, K; Nakanishi, T; Seguchi, M | 1 |
| Newton, RC; Orlinska, U | 2 |
| Bianchi, G; Ferrandi, M; Ferrari, P; Hanozet, GM; Parenti, P | 1 |
| Cragoe, EJ; Heagerty, AM; Izzard, AS | 1 |
| Kroll, MH; Luzzatto, G; Schafer, AI; Zavoico, GB | 1 |
| Cragoe, EJ; Hamm, LL; Hering-Smith, KS; Weiner, D | 1 |
| Casavola, V; Helmle-Kolb, C; Montrose, MH; Murer, H | 1 |
| Bastl, CP; Bressler, L; Cragoe, EJ; Mendez, M; Schulman, G | 1 |
| Benos, DJ; Bubien, JK; Robinson, DH; Smith, PR | 1 |
| Alpern, RJ; Cano, A; Horie, S; Miller, RT; Moe, OW; Preisig, PA | 1 |
| Baier, W; Della Bruna, R; Kurtz, A; Scholz, H | 1 |
| Arkhammar, P; Berggren, PO; Juntti-Berggren, L; Nilsson, T; Rorsman, P | 1 |
| Gesek, FA; Mishkind, MT; Schoolwerth, AC | 1 |
| Adelberg, EA; Aronson, PS; Haggerty, JG; Reilly, RF; Slayman, CW | 1 |
| Gesek, FA; Schoolwerth, AC | 4 |
| Ghysel-Burton, J; Godfraind, T | 1 |
| Cingolani, HE; Gende, OA | 3 |
| Gold, MR; Strichartz, GR | 1 |
| Brown, CE; Cragoe, EJ; Duff, HJ; Rahmberg, M | 1 |
| Ganz, MB; Vignery, A; Wang, F | 1 |
| Cragoe, EJ; Hamm, LL; Herndon, J; Merli, C; Simon, EE | 2 |
| Dhar, H; Frighi, V; Lewis, A; Ng, LL | 1 |
| Ishikawa, Y; Ogawa, A; Sasakawa, S | 2 |
| Cragoe, EJ; Fukunaka, M; Imamura, H; Kagawa, K; Kato, Y; Ko, T; Otani, H; Sakurai, Y; Tanaka, K | 1 |
| Gesek, FA; Strandhoy, JW | 1 |
| Benos, DJ; Bridges, RJ; Matalon, S | 1 |
| Bobik, A; Cragoe, EJ; Grinpukel, S; Grooms, A; Little, PJ | 1 |
| Dart, AM; Riemersma, RA | 1 |
| Buckler, KJ; Nye, PC; Peers, C; Vaughan-Jones, RD | 1 |
| Chan, YL; Wang, T | 2 |
| Batlle, DC; Rombola, G; Saleh, A | 1 |
| Battle-Tracy, KM; Owen, NE; Zaragoza, R | 1 |
| Cragoe, EJ; Deth, RC; Jagadeesh, G | 1 |
| Binder, HJ; Rajendran, VM | 1 |
| Montrose, MH; Murer, H | 2 |
| Allen, JC; Cragoe, EJ; Halligan, RD; Kahn, AM; Shelat, H | 1 |
| Bomford, J; Frighi, V; Garrido, MC; Ng, LL; Simmons, D | 1 |
| Boron, WF; Boyarsky, G; Cragoe, EJ; Ganz, MB | 1 |
| Bobik, A; Cragoe, EJ; Little, PJ; Neylon, CB | 1 |
| Avanzi, GC; Bosia, A; Brizzi, MF; Bussolino, F; Costamagna, C; Garbarino, G; Ghigo, D; Pegoraro, L | 1 |
| Brock, TA; Cragoe, EJ; Danthuluri, NR; Escobales, N; Longo, E | 1 |
| Berk, BC; Elder, E; Mitsuka, M | 1 |
| Helmle-Kolb, C; Montrose, MH; Murer, H | 1 |
| Käsmayr, J; Theisen, K; Wehling, M | 1 |
| Bobik, A; Cragoe, EJ; Little, PJ; Neylon, CB; Weissberg, PL | 1 |
| Boeynaems, JM; Boutherin-Falson, O; Cragoe, EJ; Demolle, D; Lecomte, M; Nairn, AC | 1 |
| Cragoe, EJ; Jamieson, GP; Jopson, M; Mayger, W; Wiley, JS | 1 |
| Cragoe, EJ; Mandel, LJ; Soltoff, SP | 1 |
| Bobik, A; Cragoe, EJ; Little, PJ | 1 |
| Finet, M; Godfraind, T | 1 |
| Cragoe, EJ; Kim, D; Smith, TW | 1 |
| Allen, JC; Cragoe, EJ; Kahn, AM; Shelat, H; Zimmer, R | 1 |
| Cragoe, EJ; Lake, JR; Renner, EL; Scharschmidt, BF | 1 |
| Alessi, D; Bosia, A; Bussolino, F; Costamagna, C; Ghigo, D; Mantovani, A; Pescarmona, G; Turrini, F; Wang, JM | 1 |
| Boeynaems, JM; Cragoe, EJ; Demolle, D; Lagneau, C | 1 |
| Bergui, L; Bosia, A; Cappio, FC; Gaidano, G; Ghigo, D; Schena, M; Treves, S; Turrini, F | 1 |
| Cragoe, EJ; Deth, RC; Gupta, S | 1 |
| Gorman, RR; Knapik, J; Owen, NE; Strebel, F; Tarpley, WG | 1 |
| Cragoe, EJ; Gerritsen, ME; Medow, MS; Moatter, T; Perry, CA | 1 |
| Cragoe, EJ; Manejwala, FM; Schultz, RM | 1 |
| Khodorov, BI; Mokh, VP; Vasilets, LA | 1 |
| Cook, CA; Holmsen, H; Steen, VM; Tysnes, OB | 1 |
| Allen, JC; Cragoe, EJ; Kahn, AM; Shelat, H | 1 |
| Alvarez, J; García-Sancho, J; Mollinedo, F; Sanchez, A | 1 |
| Hockaday, TD; Ruiz Palomo, F; Toledo, T | 1 |
| Blazer-Yost, BL; Cox, M; Furlanetto, R | 1 |
| Binder, HJ; Kashgarian, M; Rajendran, VM | 1 |
| Kaesler, B; Schönheit, P | 1 |
| Michael-Hepp, J; Schömig, E; Schönfeld, CL | 1 |
| Bastl, CP; Cragoe, EJ; Schulman, G | 1 |
| Hambleton, S; Watson, SP | 1 |
| Damais, C; Frelin, C; Krawice, I; Ladoux, A | 1 |
| Boron, WF; Boyarsky, G; Cragoe, EJ; Ransom, B; Schlue, WR | 1 |
| Cragoe, EJ; Friesen, HG; Jacobs, HK; Murphy, PR; Too, CK; Walker, A | 1 |
| Cragoe, EJ; Friesen, HG; Too, CK | 1 |
| Blair, IA; Cragoe, EJ; Frazer, M; Limbird, LE; Reed, PW; Schwartzberg, MS; Sweatt, JD | 1 |
| Cragoe, EJ; Gárdos, G; Hunyady, L; Sarkadi, B; Spät, A | 1 |
| Alonso, MT; Collazos, JM; Sanchez, A | 1 |
| Cragoe, EJ; Zavoico, GB | 1 |
| Adelberg, EA; Agarwal, N; Cragoe, EJ; Haggerty, JG; Slayman, CW | 1 |
| Biber, TU; Cragoe, EJ; Drewnowska, K | 1 |
| Bosia, A; Bussolino, F; Cragoe, EJ; Garbarino, G; Ghigo, D; Heller, R; Pegoraro, L; Pescarmona, G; Turrini, F | 1 |
| Asher, C; Cragoe, EJ; Garty, H; Moran, A | 1 |
| Boron, WF; Boyarsky, G; Ganz, MB; Sterzel, RB | 2 |
| Burckhardt, G; Friedrich, T | 1 |
| Benos, DJ; Bridges, RJ; Cragoe, EJ; Frizzell, RA | 1 |
| Frelin, C; Lazdunski, M; Vigne, P | 1 |
| Cragoe, EJ; Johnson, SL; Limbird, LE; Sweatt, JD | 1 |
| Blair, IA; Cragoe, EJ; Limbird, LE; Sweatt, JD | 1 |
| Akkerman, JW; Gorter, G; Riemens, T; Scheid, P; Siffert, G; Siffert, W | 1 |
| Scheid, P; Siffert, G; Siffert, W | 1 |
| Cook, JS; Cragoe, EJ; Shaffer, C | 1 |
| Cragoe, EJ; Frelin, C; Lazdunski, M; Vigne, P | 1 |
| Calonge, ML; Ilundáin, AA; Peral, MJ | 2 |
| Czachurski, J; König, SA; Offner, B; Seller, H | 1 |
| Biber, TU; Lyall, V | 1 |
| Cáceres-Cortés, J; Dumouchel, J; Haddad, P; Hoang, T; Rajotte, D | 1 |
| Chang, E; Kleyman, TR; Lin, C; Meo, P; Musch, M; Zebrowitz, J | 1 |
| Kawai, N; McCarron, RM; Spatz, M; Yamamoto, H; Yamamoto, T | 1 |
| Highsmith, RF; Hubel, CA | 1 |
| Ikeda, T; Noël, J; Orlowski, J; Pouysségur, J; Schmitt, B; Shigekawa, M; Wakabayashi, S | 1 |
| Komano, Y; Nakamura, T; Unemoto, T | 1 |
| Alpern, RJ; Amemiya, M; Cano, A; Moe, OW; Yamaji, Y | 1 |
| Arruda, JA; Pahlavan, P; Ruiz, OS; Wang, LJ | 1 |
| Balkovetz, DF; Wang, D; Warnock, DG | 1 |
| Donowitz, M; Levine, SA; Little, PJ; Montrose, MH; Pouyssegur, J; Tse, CM; Yun, CH | 1 |
| Arrieta, J; Battle, DC; Daugirdas, JT; Flores, G; Ye, M | 1 |
| Capasso, G; Ciani, F; De Santo, NG; De Tommaso, G; Russo, F; Unwin, R; Vinciguerra, M | 1 |
| Barry, WH; Livsey, C; Matsui, H; Spitzer, KW | 1 |
| Bobik, A; Cragoe, EJ; Farrelly, CA; Little, PJ; Neylon, CB; Weissberg, PL | 1 |
| Rosskopf, D; Schröder, KJ; Siffert, W | 1 |
| Bugge, E; Ytrehus, K | 1 |
| Capogrossi, MC | 1 |
| Baron, R; Boron, WF; Eisen, T; Ravesloot, JH | 1 |
| Camilión de Hurtado, MC; Cingolani, HE; Pérez, NG | 1 |
| Baker, RR; Benos, DJ; Bradford, AL; Ismailov, I; Matalon, S; Senyk, O | 1 |
| Abriel, H; Katz, U; Kucera, P | 1 |
| Cohen, SM; Maron, R; Navon, G; Werrmann, JG | 1 |
| Avkiran, M; Hearse, DJ; Ibuki, C; Yasutake, M | 1 |
| Bechtner, G; Christ, M; Douwes, K; Eisen, C; Theisen, K; Wehling, M | 1 |
| Eastman, A; Li, J | 1 |
| Hasuda, K; Lee, C; Tannock, IF | 1 |
| Bova, S; Cannas, S; Cargnelli, G; Debetto, P; Luciani, S | 1 |
| Civati, G; Colussi, G; Guastoni, C; Minetti, L; Rombolà, G | 1 |
| Collado-Escobar, D; Mollinedo, F; Pérez-Sala, D | 1 |
| Grady, C; Gupta, S; McArthur, C; Ruderman, NB | 1 |
| Abrahamse, SL; Bindels, RJ; van Os, CH; Vis, A | 1 |
| Cragoe, EJ; Griffin, RJ; Kim, GE; Lyons, JC; Makepeace, CM; Rao, GH; Song, CW | 1 |
| Cragoe, EJ; Fu, WJ; Kuwahara, M; Marumo, F | 1 |
| Haigney, MC; Lakatta, EG; Silverman, HS; Stern, MD | 1 |
| Matalon, S; Shoemaker, RL; Yue, G | 1 |
| Good, DW; Watts, BA | 1 |
| Cragoe, EJ; Griffin, RJ; Lyons, JC; Makepeace, CM; Song, CW | 1 |
| Soares-da-Silva, P | 1 |
| Albrecht, T; Altamirano, AA; Cragoe, EJ; Fons, MP; Russell, JM | 1 |
| Grace, AA; Metcalfe, JC; Vandenberg, JI | 1 |
| Negulyaev, YA; Vedernikova, EA | 1 |
| Alton, EW; Geddes, DM; Graham, A; Steel, DM | 1 |
| Griffin, RJ; Lyons, JC; Makepeace, CM; Song, CW | 1 |
| Benos, DJ; Cragoe, EJ; Hu, P; Jilling, T; Matalon, S; Oh, Y; Shoemaker, RL; Yue, G | 1 |
| Marcus, DC; Shiga, N; Wangemann, P | 1 |
| Dobrowsky, E; Karuri, AR; Tannock, IF | 1 |
| Crevat, A; Gallice, P; Kovacic, H; Sarrazin, M | 1 |
| Clark, MD; Cragoe, EJ; Kirk, KA; Kitakaze, M; Luo, CS; Madden, MC; Pike, MM; Pohost, GM | 1 |
| Ayuso, MS; Butta, N; Ciprés, G; Martín-Requero, A; Parrilla, R; Urcelay, E | 1 |
| Boron, WF; Kaplan, DL | 1 |
| Novak, I; Pahl, C | 1 |
| Cragoe, EJ; Kuwahara, M; Marumo, F; Sasaki, S; Uchida, S | 1 |
| Astashkin, EI; Khodorova, AB; Surin, AM | 1 |
| Albus, U; Englert, HC; Lang, HJ; Linz, W; Martorana, PA; Schölkens, BA; Scholz, W | 1 |
| Fernandes, MH; Pestana, M; Soares-da-Silva, P | 1 |
| Cragoe, EJ; Maidorn, RP; Tannock, IF | 1 |
| Bosia, A; Ghigo, D; Ginsburg, H; Nissani, E; Pescarmona, GP; Turrini, F | 1 |
| Davies, JE; Ng, LL; Quinn, P | 1 |
| Cragoe, EJ; David, P; Karlish, SJ; Mayan, H | 1 |
| Mayer, SE; Sanders-Bush, E | 1 |
| Asher, C; Barbry, P; Clauss, W; Cragoe, E; Garty, H; Goldstein, O | 1 |
| Agulian, SK; Aronson, PS; Giebisch, G; Wang, T | 1 |
| Greco, NJ; Jamieson, GA; Jones, GD; Kitagawa, S; Tandon, NN; Tenner, TE | 1 |
| Kleyman, TR; Marunaka, Y; O'Brodovich, H; Tohda, H; Wang, X | 1 |
| Chan, YL; Giebisch, G; Malnic, G; Wang, T | 1 |
| Alpern, RJ; Baum, M; Cano, A | 1 |
| Acevedo, M; Steele, LW | 1 |
| Kranzhöfer, R; Kübler, W; Lang, HJ; Metz, J; Pestel, E; Schirmer, J; Schömig, A; von Hodenberg, E | 1 |
| Berk, BC; Mitsuka, M; Nagae, M | 1 |
| Dimroth, P; Kluge, C | 1 |
| Dobrovinskaya, OR; Gukovskaya, AS; Korystov, YN; Shaposhnikova, VV; Trepakova, ES | 1 |
| Cragoe, EJ; Keku, TO; Orlando, RC; Reddy, SP; Tobey, NA | 1 |
| Boron, WF; Boyarsky, G; Davis, MB; Ransom, B; Schlue, WR | 1 |
| Cragoe, EJ; Fliegel, L; Haworth, RS | 1 |
| Donowitz, M; Levine, SA; Little, PJ; Nath, SK; Pouyssegur, J; Tse, CM; Yun, CH | 1 |
| Batlle, D; Flores, G; Ye, M | 1 |
| Astashkin, EN; Diachenko, VI; Fokin, AV; Khodorova, AB; Kolomiets, AF; Surin, AM | 1 |
| Hill, RP; Liu, FF; Sherar, MD | 1 |
| George, T; Good, DW; Watts, BA | 2 |
| Asano, Y; Kawakami, K; Muto, S; Nagano, K; Nemoto, J; Ohtaka, A; Watanabe, Y; Yamaki, M | 1 |
| Incerpi, S; Leoni, S; Spagnuolo, S; Terenzi, F | 1 |
| Tannock, IF; Yamagata, M | 1 |
| Anderie, I; Thévenod, F | 1 |
| Katz, AI; Ominato, M; Satoh, T | 1 |
| Kandasamy, RA; Orlowski, J | 1 |
| Burnard, SL; Head, RJ; Leifert, WR; McMurchie, EJ; Patten, GS | 1 |
| Pappas, CA; Pizzonia, JH; Ransom, BR | 1 |
| Bethell, HW; Grace, AA; Metcalfe, JC; Vandenberg, JI; Weissberg, PL | 1 |
| Abbiati, T; Aronson, PS; Egbert, AL; Giebisch, G; Wang, T | 1 |
| Alvarez, B; Cingolani, HE; Mattiazzi, A; Pérez, GN; Vila-Petroff, M | 1 |
| Liu, J; Shiga, N; Wangemann, P | 1 |
| Civelek, VN; Corkey, BE; Hamilton, JA; Kelly, KL; Tornheim, K | 1 |
| Gekle, M; Golenhofen, N; Oberleithner, H; Silbernagl, S | 1 |
| Diep, K; Hill, RP; Liu, FF | 1 |
| Chapman, RA; Chatamra, KR | 1 |
| Bertsch, G; Hoppe, J; Leicht, M; Simm, A | 1 |
| Ko, Y; Sachinidis, A; Seewald, S; Seul, C; Vetter, H | 1 |
| Bril, A; Khandoudi, N; Laville, MP | 1 |
| Bosia, A; Ghigo, D; Giorgianni, A; Pannocchia, A; Revelli, S; Tamponi, G; Todde, R | 1 |
| Batlle, D; Fioretto, P; LaPointe, MS; Lurbe, A; Mauer, M | 1 |
| Ghosh, TK; Mathew, OP; Van Scott, MR | 1 |
| Alzola, E; Chaib, N; Dehaye, JP; Grosfils, K; Kabré, E; Lachish, M; Marino, A; Métioui, M; Moran, A | 1 |
| Lanzer, M; Sanchez, CP; Wünsch, S | 1 |
| Endoh, M; Talukder, MA | 1 |
| Iturriaga, R; Lahiri, S; Mokashi, A | 1 |
| Kuo, SH; Liaw, YS; Lin, YJ; Luh, KT; Wu, ML; Yang, PC; Yu, CJ | 1 |
| Bembry, J; Kawai, N; McCarron, RM; Merkel, N; Spatz, M | 1 |
| Hamm, PH; Jackson, DC; Lawler, RG; Meyers, RS; Shi, H | 1 |
| Berka, JL; Cooper, ME; Harris, PJ; Hiranyachattada, S; Kelly, DJ; Nobes, M; Wookey, PJ | 1 |
| Anderson, KM; Bonomi, P; Buyn, T; Dudeja, P; Harris, JE; Meng, J; Ou, D; Sawlani, D; Seed, T | 1 |
| Medzihradsky, F; Yabaluri, N | 1 |
| Ikeda, T; Pouysségur, J; Schmitt, B; Shigekawa, M; Wakabayashi, S | 1 |
| Asano, Y; Hiramoto, K; Kikugawa, K; Tomiyama, S | 1 |
| Ciampolillo, F; Green, RB; Stanton, BA; Vandorpe, DH | 1 |
| Desoignie, R; Sellin, JH | 1 |
| Matalon, S; Yue, G | 1 |
| Li, JH; Liu, FF | 1 |
| Brew, BK; Cook, DI; Field, MJ; Györy, AZ; Johnson, DW; Pollock, CA; Poronnik, P | 1 |
| Calonge, ML; de la Horra, MC; Ilundáin, AA | 1 |
| Ramasamy, R; Schaefer, S | 2 |
| Dagher, G; Griffiths, N; Sauterey, C; Siaume-Perez, S; Thomas, SR | 1 |
| Fung, ML; Haddad, GG | 1 |
| Anderson, SE; Cala, PM; Liu, H | 1 |
| Dukhanin, AS; Galenko-Iaroshevskiĭ, PA; Khankoeva, AI | 1 |
| Greksák, M; Majerník, A; Smigán, P | 1 |
| Milton, AE; Weiner, ID | 1 |
| Soares-da-Silva, P; Vieira-Coelho, MA | 1 |
| Kawakita, M; Suzuki, T; Yoshioka, S | 1 |
| Cox, T | 1 |
| Chaturapanich, G; Cook, DI; Dinudom, A; Ishibashi, H; Young, JA | 1 |
| Giebisch, G; Lu, M; Wang, W | 1 |
| Cook, DI; Field, MJ; Johnson, DW; Pollock, CA; Poronnik, P; Saunders, HJ | 1 |
| Alpern, RJ; Ambühl, P; Amemiya, M; Moe, OW; Preisig, PA | 1 |
| Abbott, DE; Brokl, OH; Dantzler, WH; Martinez, CL; Shuprisha, A | 2 |
| Gekle, M; Grosse-Wortmann, L; Lanzer, M; Sanchez, CP; Wiesner, J; Wünsch, S | 1 |
| Aksentsev, SL; Hamet, P; Orlov, SN; Pokudin, NI; Tremblay, J | 1 |
| Ando, H; Fujita, M; Hotta, Y; Ishikawa, N; Nakagawa, J; Sakakibara, J; Takeya, K | 1 |
| Cohen, MV; Downey, JM; Liu, GS; Miki, T; Sato, H; Vallabhapurapu, RP; Wang, P | 1 |
| Audette, M; Charest-Gaudreault, R; Poulin, R; Verma, S; Zhao, C | 1 |
| Alvarez, BV; Camilión de Hurtado, MC; Cingolani, HE; Ennis, IL; Pérez, NG | 2 |
| Damgaard, I; Hoffmann, EK; Jørgensen, NK; Pedersen, SF; Schousboe, A | 1 |
| Ruigrok, TJ; Schreur, JH; Van Echteld, CJ; Van Emous, JG | 1 |
| Barbry, P; Champigny, G; Coscoy, S; Darboux, I; Lazdunski, M; Lingueglia, E | 1 |
| Wesson, DE | 1 |
| Du, HK; Hales, CA; Quinn, DA; Thompson, BT | 1 |
| Lee, AH; Tannock, IF | 1 |
| Mori, N; Wu, D | 1 |
| Anderie, I; Blum, R; Grinstein, S; Haase, W; Thévenod, F | 1 |
| Engler, RL; Gottlieb, RA; Karwatowska-Prokopczuk, E; Li, HL; Nordberg, JA | 1 |
| Fitzgerald, RC; Omary, MB; Triadafilopoulos, G | 1 |
| Gekle, M; Silbernagl, S; Wünsch, S | 1 |
| Hamet, P; Kuznetsov, SR; Orlov, SN; Pokudin, NI; Tremblay, J | 1 |
| Faber, S; Hock, FJ; Lang, HJ; Mutschler, E; Schölkens, BA | 1 |
| Banerjee, A; Cain, BS; Cleveland, JC; Harken, AH; Meldrum, DR; Rehring, TF; Shapiro, JI | 1 |
| Marin-Grez, M; Wimberger, P | 1 |
| Pi, Y; Walker, JW | 1 |
| Fitz, JG; Garnovskaya, MN; Liddle, RA; Prpic, V; Raymond, JR; Wang, Y | 1 |
| Brunette, MG; Claveau, D; Leclerc, M; Pellerin, I | 1 |
| Bugge, E; Løkebø, JE; Munch-Ellingsen, J; Ytrehus, K | 1 |
| Alvarez, BV; Camilión de Hurtado, MC; Cingolani, HE; Ennis, IL | 1 |
| Giebisch, G; Shirley, DG; Unwin, RJ; Walter, SJ | 1 |
| O'Regan, MH; Phillis, JW; Song, D | 1 |
| Hoffmann, EK; Lambert, IH; Pedersen, S; Pedersen, SF | 1 |
| Baltz, JM; Bavister, BD; Lane, M | 2 |
| Bell, PD; Peti-Peterdi, J | 1 |
| Cheng, CP; Little, WC; Ohte, N; Suzuki, M; Wang, ZM; Williams, DL | 1 |
| Butterfield, I; Sandle, GI | 1 |
| De Vito, P; Farias, RN; Incerpi, S; Luly, P | 1 |
| Amsallem, H; Chaib, N; Dehaye, JP; Kabré, E; Moran, A; Vandermeers, MC | 1 |
| Attaphitaya, S; Melvin, JE; Park, K | 1 |
| Bookstein, C; Chang, EB; Melvin, JE; Olschowka, JA; Park, K; Richardson, LA | 1 |
| Abdulnour-Nakhoul, S; Bor, S; Imeryuz, N; Orlando, RC | 1 |
| Bashi, E; Bevensee, MO; Boron, WF; Boyarsky, G; Schlue, WR | 1 |
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| Hershfinkel, M; Lewis, EC; Nita, II; Sekler, I | 1 |
| Boyle, D; Dymowska, AK; Goss, GG; Schultz, AG | 1 |
| Brines, L; Calvo, C; Canto, ID; Chorro, FJ; Soler, C; Such, L; Such-Miquel, L; Tormos, Á; Trapero, I; Zarzoso, M | 1 |
| Fliegel, L; Goss, GG; Guffey, SC | 1 |
| Acevedo-Olvera, LF; Caceres-Cortes, JR; Caceres-Perez, AA; Diaz-Garcia, H; Gutierrez-Iglesias, G; Parra-Barrera, A; Rangel-Corona, R | 1 |
| Du, X; Li, J; Xu, B; Yamagata, N; Zhou, J | 1 |
| Amelkina, GA; Genrikhs, EE; Isaev, NK; Ivashkin, EG; Khaspekov, LG; Novikova, SV; Stelmashook, EV | 1 |
| Aoki, W; Imazawa, R; Ito, M; Sano, M; Takahashi, Y | 1 |
| Jiang, H; Lade, J; Shimoda, LA; Undem, C; Walker, J; Yun, X | 1 |
| Artursson, P; Miyake, M; Nakai, D; Ragnarsson, E | 1 |
| Akao, Y; Kumazaki, M; Kuranaga, Y; Shinohara, H; Taniguchi, K; Tsujimura, N; Yamada, NO | 1 |
| Du, Y; Li, L; Li, Y; Shang, BY; Xu, XD; Zhen, YS; Zhu, BY | 1 |
| Black, KM; Delpeut, S; Richardson, CD; Sisson, G | 1 |
| Ding, Z; Han, C; Hou, X; Jiang, Y; Lin, R; Qian, W; Shi, H; Zhao, X | 1 |
| Brauner, CJ; Brix, KV; Schluter, D; Wood, CM | 1 |
| Alesi, N; Belaid, A; Filippakis, H; Henske, EP; Hougard, T; Lam, HC; Nijmeh, J; Siroky, B; Wu, C | 1 |
| Chu, JJH; Lee, CHR; Mohamed Hussain, K | 1 |
| Bleich, M; Himmerkus, N; Hu, MY; Melzner, F; Ramesh, K | 1 |
| Barber, DL; Kisor, K; Manoli, SS; Webb, BA | 1 |
| Balza, E; Carlone, S; Carta, S; Castellani, P; Cossu, V; Marini, C; Piccioli, P; Rubartelli, A; Sambuceti, G | 1 |
3 review(s) available for ethylisopropylamiloride and amiloride
| Article | Year |
|---|---|
Na+/H+ antiporter, chloroquine uptake and drug resistance: inconsistencies in a newly proposed model.
Topics: Amiloride; Animals; Antimalarials; Chloroquine; Drug Resistance; Humans; Malaria, Falciparum; Plasmodium falciparum; Sodium-Hydrogen Exchangers; Vacuoles | 1999 |
Ion exchangers mediating NaCl transport in the renal proximal tubule.
Topics: Absorption; Amiloride; Animals; Anions; Biological Transport, Active; Formates; Ion Transport; Kidney Tubules, Proximal; Microvilli; Oxalates; Sodium Chloride; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers | 2002 |
Sodium-proton exchange in crayfish.
Topics: Adaptation, Physiological; Amiloride; Animals; Astacoidea; Models, Animal; Sodium; Sodium Channels; Sodium-Hydrogen Exchangers; Vacuolar Proton-Translocating ATPases | 2002 |
565 other study(ies) available for ethylisopropylamiloride and amiloride
| Article | Year |
|---|---|
NHE1 inhibition by amiloride- and benzoylguanidine-type compounds. Inhibitor binding loci deduced from chimeras of NHE1 homologues with endogenous differences in inhibitor sensitivity.
Topics: Amiloride; Animals; Binding Sites; Cation Transport Proteins; Cell Line; Cricetinae; Cricetulus; Flounder; Guanidines; Humans; Mutation; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sodium Channel Blockers; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Species Specificity; Sulfones; Urodela | 2007 |
Cloning, sequencing, and expression of Na(+)-H+ antiporter cDNAs from human tissues.
Topics: Amiloride; Base Sequence; Carrier Proteins; Cloning, Molecular; DNA; Humans; Kidney; Molecular Sequence Data; Sodium-Hydrogen Exchangers | 1992 |
Alpha 1-adrenergic effects on intracellular pH and calcium and on myofilaments in single rat cardiac cells.
Topics: Amiloride; Animals; Calcium; Hydrogen-Ion Concentration; Myocardial Contraction; Myocardium; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1992 |
H+ extrusion by an apical vacuolar-type H(+)-ATPase in rat renal proximal tubules.
Topics: Adenosine Triphosphate; Amiloride; Animals; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Antifungal Agents; Biological Transport; Carrier Proteins; Cell Fractionation; Cytophotometry; Electrophoresis; Fluorescence; Hydrogen; Hydrogen-Ion Concentration; Kidney Tubules, Proximal; Macrolides; Male; Proton-Translocating ATPases; Rats; Rats, Inbred Strains; Sodium-Hydrogen Exchangers | 1992 |
Characterization of basolateral Na/H exchange (Na/H-1) in MDCK cells.
Topics: Amiloride; Animals; Calibration; Carrier Proteins; Cell Line; Dogs; Fluorescence; Hydrogen-Ion Concentration; Kinetics; Perfusion; Sodium; Sodium-Hydrogen Exchangers | 1992 |
Polyene macrolide antibiotics: indirect stimulation of the Na+/H+ exchanger of BALB/c B lymphoid cell line, A20.
Topics: Amiloride; Animals; Anti-Bacterial Agents; B-Lymphocytes; Candicidin; Carrier Proteins; Cell Division; Dose-Response Relationship, Drug; Fluoresceins; Fluorescence; Hydrogen-Ion Concentration; Mice; Mice, Inbred BALB C; Polyenes; Sodium-Hydrogen Exchangers; Tumor Cells, Cultured | 1992 |
Novel amiloride analog allosterically modulates the alpha 2-adrenergic receptor but does not inhibit Na+/H+ exchange.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Carrier Proteins; Cells, Cultured; Kidney; Protein Conformation; Receptors, Adrenergic, alpha; Sodium-Hydrogen Exchangers; Swine; Tritium; Yohimbine | 1992 |
Increased Na+/H+ exchange activity in vascular smooth muscle cells of spontaneously hypertensive rats and possible involvement of protein kinase C.
Topics: Amiloride; Animals; Calcium; Calmodulin; Carrier Proteins; Cells, Cultured; Hypertension; Male; Muscle, Smooth, Vascular; Protein Kinase C; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium; Sodium Radioisotopes; Sodium-Hydrogen Exchangers | 1992 |
Guanine nucleotides regulate beta-adrenergic activation of Na-H exchange independently of receptor coupling to Gs.
Topics: Amiloride; Animals; Carrier Proteins; Cells, Cultured; Cricetinae; Dogs; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Hydrogen-Ion Concentration; Ileum; Intestinal Mucosa; Isoproterenol; Kinetics; L Cells; Meglumine; Mice; Propranolol; Receptors, Adrenergic, beta; Sodium; Sodium Fluoride; Sodium-Hydrogen Exchangers; Thionucleotides; Transfection | 1992 |
Effects of Na+/H+ exchange inhibitors in cardiac ischemia.
Topics: Amiloride; Animals; Carrier Proteins; Erythrocytes; Hydrogen; In Vitro Techniques; Ion Transport; Male; Myocardial Ischemia; Rabbits; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Hydrogen Exchangers | 1992 |
Tumour cell proliferation is abolished by inhibitors of Na+/H+ and HCO3-/Cl- exchange.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Biological Transport, Active; Carrier Proteins; Cell Division; Chloride-Bicarbonate Antiporters; Mice; Mitosis; Sodium-Hydrogen Exchangers; Tumor Cells, Cultured | 1992 |
[The arrhythmogenicity of alpha 1-adrenergic stimulation following myocardial acidosis].
Topics: Acidosis; Amiloride; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzopyrans; Cardiomyopathies; Fluorescence; Fluorescent Dyes; Heart; Hydrogen-Ion Concentration; In Vitro Techniques; Myocardial Contraction; Rats; Receptors, Adrenergic, alpha | 1992 |
Na+/H(+)-exchange in A6 cells: polarity and vasopressin regulation.
Topics: Amiloride; Amphibians; Animals; Anti-Arrhythmia Agents; Arginine Vasopressin; Carrier Proteins; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Hydrogen-Ion Concentration; Inositol 1,4,5-Trisphosphate; Nephrons; Protein Kinase C; Protein Kinases; Sodium; Sodium-Hydrogen Exchangers | 1992 |
5-(N-ethyl-N-isopropyl)amiloride and mild acidosis protect cultured cerebellar granule cells against glutamate-induced delayed neuronal death.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Aspartic Acid; Cell Death; Cells, Cultured; Cerebellum; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Magnesium; Membrane Potentials; Neurons; Quisqualic Acid; Rats; Rats, Wistar | 1992 |
Vanadate stimulates system A amino acid transport activity in skeletal muscle. Evidence for the involvement of intracellular pH as a mediator of vanadate action.
Topics: Amiloride; Amino Acids; Animals; beta-Alanine; Biological Transport, Active; Cell Membrane; Glucose; Gramicidin; Hydrogen-Ion Concentration; Insulin; Kinetics; Lactates; Male; Muscles; Protein-Tyrosine Kinases; Rats; Rats, Inbred Strains; Receptor, Insulin; Vanadates | 1992 |
Effects of serotonin on intracellular pH and contraction in vascular smooth muscle.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Bicarbonates; Cells, Cultured; Chlorides; Dogs; Female; HEPES; Hydrogen-Ion Concentration; Male; Muscle Contraction; Muscle, Smooth, Vascular; Serotonin; Sodium; Stimulation, Chemical | 1992 |
HCO3(-)-dependent intracellular pH regulation in the premature myocardium.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Acidosis, Respiratory; Age Factors; Amiloride; Animals; Animals, Newborn; Bicarbonates; Chlorides; Heart; Hydrogen-Ion Concentration; In Vitro Techniques; Myocardium; Rabbits; Sodium | 1992 |
Effects of intracellular ions on interleukin-1 beta production by lipopolysaccharide-activated human monocytes.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Bicarbonates; Chlorides; Culture Media; Extracellular Space; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Interleukin-1; Intracellular Membranes; Lipopolysaccharides; Monensin; Monocytes; Protein Biosynthesis; Sodium | 1992 |
Effect of amiloride analogues on sodium transport in renal brush border membrane vesicles from Milan hypertensive rats.
Topics: Amiloride; Animals; Biological Transport, Active; Hypertension; Kidney; Membrane Potentials; Microvilli; Rats; Rats, Mutant Strains; Sodium | 1992 |
Intracellular pH in human resistance arteries in essential hypertension.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adipose Tissue; Amiloride; Anti-Arrhythmia Agents; Arteries; Bicarbonates; Biological Transport; Calibration; Carrier Proteins; Female; Fluoresceins; Homeostasis; Humans; Hydrogen-Ion Concentration; Hypertension; Male; Middle Aged; Norepinephrine; Potassium; Skin; Sodium-Hydrogen Exchangers; Vascular Resistance | 1991 |
Regulation of the phosphoinositide cycle by Na+/H+ exchange and intracellular pH in human platelets.
Topics: Amiloride; Blood Platelets; Carrier Proteins; Diglycerides; Enzyme Activation; Humans; Hydrogen-Ion Concentration; Nigericin; Phorbol Esters; Phosphatidic Acids; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Phosphorylation; Platelet Aggregation; Protein Kinase C; Sodium-Hydrogen Exchangers; Thrombin | 1991 |
Inner medullary collecting duct Na(+)-H+ exchanger.
Topics: Amiloride; Animals; Carrier Proteins; Cell Membrane; Cells, Cultured; Epithelium; Hydrogen-Ion Concentration; Kidney Medulla; Kidney Tubules, Collecting; Kinetics; Rabbits; Sodium; Sodium-Hydrogen Exchangers | 1991 |
Polarized expression of Na+/H+ exchange activities in clonal LLC-PK1 cells (Clone4 and PKE20) I. Basic characterization.
Topics: Amiloride; Ammonium Chloride; Carrier Proteins; Cell Line; Cell Membrane; Clone Cells; Fluoresceins; Fluorescent Dyes; Hydrogen-Ion Concentration; Kinetics; Sodium; Sodium-Hydrogen Exchangers; Spectrometry, Fluorescence | 1991 |
Low-dose glucocorticoids maintain Na-H exchange in distal colon of adrenalectomized rats.
Topics: Adrenalectomy; Aldosterone; Amiloride; Animals; Biological Transport; Carrier Proteins; Chlorides; Colon; Dexamethasone; Hydrogen-Ion Concentration; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Muscle, Smooth; Rats; Rectum; Reference Values; Sodium; Sodium-Hydrogen Exchangers | 1991 |
Epithelial sodium conductance in rabbit preimplantation trophectodermal cells.
Topics: Amiloride; Animals; Biological Transport, Active; Dose-Response Relationship, Drug; Electric Conductivity; Immunohistochemistry; In Vitro Techniques; Meglumine; Rabbits; Sodium; Sodium Channels; Trophoblasts | 1991 |
Differential regulation of Na/H antiporter by acid in renal epithelial cells and fibroblasts.
Topics: Acidosis; Amiloride; Animals; Carrier Proteins; Cells, Cultured; Epithelium; Kidney; Mice; Phosphoenolpyruvate Carboxykinase (GTP); Rabbits; RNA, Messenger; Sodium-Hydrogen Exchangers | 1991 |
Amiloride enhances the secretion but not the synthesis of renin in renal juxtaglomerular cells.
Topics: Amiloride; Animals; Carrier Proteins; Cells, Cultured; Juxtaglomerular Apparatus; Renin; Saralasin; Sodium-Hydrogen Exchangers | 1991 |
Glucose-induced increase in cytoplasmic pH in pancreatic beta-cells is mediated by Na+/H+ exchange, an effect not dependent on protein kinase C.
Topics: Amiloride; Ammonium Chloride; Animals; Calcium; Carrier Proteins; Cells, Cultured; Glucose; Hydrogen-Ion Concentration; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Membrane Potentials; Mice; Mice, Obese; Potassium; Protein Kinase C; Sodium; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Tolbutamide | 1991 |
Hormonal regulation of renal ammonium and glucose production are modulated by Na+/H+ exchange.
Topics: Amiloride; Ammonia; Angiotensin II; Animals; Carrier Proteins; Glucose; Hydrogen-Ion Concentration; Kidney; Male; Rats; Rats, Inbred Strains; Sodium-Hydrogen Exchangers | 1991 |
Increased Na(+)-H+ antiporter activity in apical membrane vesicles from mutant LLC-PK1 cells.
Topics: Amiloride; Animals; Carrier Proteins; Cell Fractionation; Cell Line; Cell Membrane; Clone Cells; Electrophoresis, Polyacrylamide Gel; gamma-Glutamyltransferase; Kinetics; Membrane Proteins; Mutation; Sodium; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase | 1991 |
Insulin increases Na(+)-H+ exchange activity in proximal tubules from normotensive and hypertensive rats.
Topics: Adrenergic alpha-Agonists; Amiloride; Angiotensin II; Animals; Blood Pressure; Carrier Proteins; Cyclic AMP; Dopamine; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Hypertension; Insulin; Kidney Tubules, Proximal; Parathyroid Hormone; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium; Sodium-Hydrogen Exchangers | 1991 |
Role of Na-H exchange in the inotropic action of Bay K 8644 and of ouabain in guinea-pig isolated atria.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acidosis; Amiloride; Animals; Calcium; Guinea Pigs; Heart; Hydrogen; Hydrogen-Ion Concentration; In Vitro Techniques; Ion Exchange; Myocardial Contraction; Myocardium; Ouabain; Sodium | 1990 |
The Na+/H+ exchanger role in the intracellular pH regulation of human platelets.
Topics: Acid-Base Equilibrium; Amiloride; Blood Platelets; Carrier Proteins; Cytoplasm; Humans; Hydrogen-Ion Concentration; Sodium; Sodium-Hydrogen Exchangers | 1991 |
Use-dependent block of atrial sodium current by ethylisopropylamiloride.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Chick Embryo; Dose-Response Relationship, Drug; Electrophysiology; Heart; Heart Atria; Membrane Potentials; Sodium; Sodium Channels | 1991 |
Antiarrhythmic activity of amiloride: mechanisms.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Barium; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiology; Magnesium; Potassium; Ryanodine; Tachycardia; Ventricular Function; Verapamil | 1991 |
Hormone responses of proximal Na(+)-H+ exchanger in spontaneously hypertensive rats.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic alpha-Agonists; Aging; Amiloride; Angiotensin II; Animals; Azepines; Blood Pressure; Carrier Proteins; Cyclic AMP; Dopamine; Hydrogen-Ion Concentration; Imidazoles; In Vitro Techniques; Nephrons; Norepinephrine; Parathyroid Hormone; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium; Sodium-Hydrogen Exchangers | 1991 |
Macrophages express functional receptors for calcitonin-gene-related peptide.
Topics: 1-Methyl-3-isobutylxanthine; Amiloride; Animals; Calcitonin; Calcitonin Gene-Related Peptide; Carrier Proteins; Cyclic AMP; Hydrogen-Ion Concentration; Macrophages; Peritoneal Cavity; Rats; Receptors, Calcitonin; Receptors, Cell Surface; Sodium-Hydrogen Exchangers; Sphingosine; Tetradecanoylphorbol Acetate | 1991 |
Effects of barium and 5-(N-ethyl-N-isopropyl)-amiloride on proximal tubule ammonia transport.
Topics: Amiloride; Ammonia; Animals; Barium; Biological Transport; Drug Combinations; Kidney Tubules, Proximal; Osmolar Concentration; Rats; Rats, Inbred Strains | 1992 |
Na+/H+ antiport and buffering capacity in human polymorphonuclear and mononuclear leucocytes.
Topics: Adult; Amiloride; Anti-Arrhythmia Agents; Buffers; Carrier Proteins; Female; Humans; Hydrogen; Hydrogen-Ion Concentration; In Vitro Techniques; Leukocytes; Lymphocytes; Male; Meglumine; Neutrophils; Sodium Chloride; Sodium-Hydrogen Exchangers | 1991 |
Changes of platelet functions by extracellular sodium ion.
Topics: Amiloride; Arachidonic Acids; Blood Platelets; Calcimycin; Cytoplasm; Humans; Hydrogen-Ion Concentration; Indomethacin; Platelet Aggregation; Serotonin; Sodium; Thrombin; Tissue Plasminogen Activator | 1991 |
Effects of amiloride and an analogue on ventricular arrhythmias, contracture and cellular injury during reperfusion in isolated and perfused guinea pig heart.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Calcium; Contracture; Coronary Circulation; Guinea Pigs; In Vitro Techniques; Myocardial Reperfusion Injury; Myocardium; Sodium | 1991 |
Hormonal interactions with the proximal Na(+)-H+ exchanger.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amiloride; Angiotensin II; Animals; Carrier Proteins; Dopamine; Hormones; In Vitro Techniques; Kidney Tubules; Norepinephrine; Parathyroid Hormone; Rats; Sodium; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 1990 |
Dual interactions between alpha 2-adrenoceptor agonists and the proximal Na(+)-H+ exchanger.
Topics: Adrenergic alpha-Agonists; Amiloride; Animals; Azepines; Carrier Proteins; Dose-Response Relationship, Drug; Guanabenz; Kidney Tubules, Proximal; Male; Pertussis Toxin; Rats; Rats, Inbred Strains; Sodium; Sodium-Hydrogen Exchangers; Trypsin; Virulence Factors, Bordetella | 1990 |
Amiloride-inhibitable Na+ conductive pathways in alveolar type II pneumocytes.
Topics: Alkaline Phosphatase; Amiloride; Animals; Biological Transport, Active; Cell Membrane; Cell Separation; Cells, Cultured; Hydrogen-Ion Concentration; Kinetics; Macrophages; Pulmonary Alveoli; Rabbits; Sodium; Time Factors; Valinomycin | 1991 |
Ethylisopropylamiloride-sensitive pH control mechanisms modulate vascular smooth muscle cell growth.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Aorta; Blood; Cattle; Cell Division; Cells, Cultured; Culture Media; DNA Replication; Hydrogen-Ion Concentration; Kinetics; Muscle, Smooth, Vascular; Protein Biosynthesis; Rats; Rats, Inbred Strains | 1991 |
Noradrenaline release from the rat heart during anoxia: effects of changes in extracellular sodium concentration and inhibition of sodium uptake mechanisms.
Topics: Amiloride; Animals; Extracellular Space; Hypoxia; In Vitro Techniques; Lidocaine; Male; Myocardium; Norepinephrine; Rats; Rats, Inbred Strains; Sodium | 1991 |
Intracellular pH and its regulation in isolated type I carotid body cells of the neonatal rat.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Animals, Newborn; Bicarbonates; Buffers; Carotid Body; Hydrogen-Ion Concentration; Meglumine; Rats; Sodium; Spectrometry, Fluorescence | 1991 |
Time- and dose-dependent effects of protein kinase C on proximal bicarbonate transport.
Topics: Amiloride; Animals; Bicarbonates; Biological Transport; Carbon Dioxide; Enzyme Activation; Glucose; Ion Exchange; Kidney Tubules, Proximal; Male; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Time Factors | 1990 |
Reduced intracellular pH in lymphocytes from the spontaneously hypertensive rat.
Topics: Amiloride; Animals; Bicarbonates; Body Fluids; Carbon Dioxide; Carrier Proteins; Homeostasis; Hydrogen; Hydrogen-Ion Concentration; Intracellular Fluid; Lymphocytes; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Sodium; Sodium-Hydrogen Exchangers | 1990 |
Heparin inhibits Na(+)-H+ exchange in vascular smooth muscle cells.
Topics: Amiloride; Angiotensin II; Animals; Aorta, Thoracic; Carrier Proteins; Cattle; Cells, Cultured; Endothelium, Vascular; Epidermal Growth Factor; Glycosaminoglycans; Heparin; Hydrogen-Ion Concentration; Inositol; Inositol 1,4,5-Trisphosphate; Kinetics; Male; Mice; Mice, Inbred Strains; Muscle, Smooth, Vascular; Ouabain; Platelet-Derived Growth Factor; Rats; Rats, Inbred WF; Sodium; Sodium-Hydrogen Exchangers | 1990 |
Modulation of bovine aortic alpha-2 receptors by Na+, 5'-guanylylimidodiphosphate, amiloride and ethylisopropylamiloride: evidence for receptor G-protein precoupling.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Binding, Competitive; Cattle; Cell Membrane; GTP-Binding Proteins; Guanylyl Imidodiphosphate; In Vitro Techniques; Kinetics; Muscle, Smooth, Vascular; Receptors, Adrenergic, alpha; Sodium; Yohimbine | 1990 |
Characterization of Na-H exchange in apical membrane vesicles of rat colon.
Topics: Amiloride; Animals; Carrier Proteins; Cations; Cell Membrane; Colon; Hydrogen-Ion Concentration; Kinetics; Magnesium; Muscle, Smooth; Rats; Rats, Inbred Strains; Sodium; Sodium Radioisotopes; Sodium-Hydrogen Exchangers | 1990 |
Polarity and kinetics of Na(+)-H+ exchange in cultured opossum kidney cells.
Topics: Amiloride; Animals; Carrier Proteins; Cell Line; Cells, Cultured; Fluoresceins; Fluorescent Dyes; Hydrogen-Ion Concentration; Kidney; Kinetics; Mathematics; Models, Biological; Opossums; Quaternary Ammonium Compounds; Sodium; Sodium-Hydrogen Exchangers; Spectrometry, Fluorescence | 1990 |
Na(+)-H+ and Na(+)-dependent Cl(-)-HCO3- exchange control pHi in vascular smooth muscle.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Bicarbonates; Cells, Cultured; Chlorides; Dogs; Female; Femoral Artery; Fluoresceins; Fluorescent Dyes; Hydrogen-Ion Concentration; Kinetics; Male; Muscle, Smooth, Vascular; Sodium; Spectrometry, Fluorescence | 1990 |
Effect of protein kinase C modulators on the leucocyte Na+/H+ antiport in type 1 (insulin-dependent) diabetic subjects with albuminuria.
Topics: Albuminuria; Alkaloids; Amiloride; Blood Glucose; Carrier Proteins; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Glycated Hemoglobin; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Insulin; Kinetics; Leukocytes; Protein Kinase C; Sodium-Hydrogen Exchangers; Staurosporine | 1990 |
Intracellular-pH dependence of Na-H exchange and acid loading in quiescent and arginine vasopressin-activated mesangial cells.
Topics: Amiloride; Animals; Arginine Vasopressin; Carrier Proteins; Cells, Cultured; Glomerular Mesangium; Hydrogen-Ion Concentration; Kinetics; Mitogens; Rats; Sodium; Sodium-Hydrogen Exchangers | 1990 |
Intracellular pH in human arterial smooth muscle. Regulation by Na+/H+ exchange and a novel 5-(N-ethyl-N-isopropyl)amiloride-sensitive Na(+)- and HCO3(-)-dependent mechanism.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Acid-Base Equilibrium; Adenosine Triphosphate; Aged; Amiloride; Ammonium Chloride; Bicarbonates; Buffers; Cells, Cultured; Energy Metabolism; Fluoresceins; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Mammary Arteries; Middle Aged; Muscle, Smooth, Vascular; Protons; Sodium; Sodium Radioisotopes | 1990 |
Evidence for a role of the Na+/H+ exchanger in the colony-stimulating-factor-induced ornithine decarboxylase activity and proliferation of the human cell line M-07e.
Topics: Amiloride; Carrier Proteins; Cell Division; Cell Line; DNA Replication; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hydrogen-Ion Concentration; Interleukin-3; Ornithine Decarboxylase; Protein Kinase C; Sodium-Hydrogen Exchangers; Subcellular Fractions; Tetradecanoylphorbol Acetate; Thymidine; Tritium | 1990 |
Osmotic activation of Na(+)-H+ exchange in human endothelial cells.
Topics: Amiloride; Carrier Proteins; Cells, Cultured; Endothelium, Vascular; Humans; Hydrogen-Ion Concentration; Kinetics; Osmolar Concentration; Sodium; Sodium-Hydrogen Exchangers | 1990 |
Hypertrophy and hyperplasia cause differing effects on vascular smooth muscle cell Na+/H+ exchange and intracellular pH.
Topics: Amiloride; Angiotensin II; Animals; Aorta, Thoracic; Blood; Cell Division; Hydrogen-Ion Concentration; Hyperplasia; Hypertrophy; Kinetics; Male; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Protein Kinase C; Protons; Rats; Rats, Inbred Strains; Sodium | 1990 |
Parathyroid hormone regulation of Na+/H+ exchange in opossum kidney cells: polarity and mechanisms.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Carrier Proteins; Cell Line; Colforsin; Dose-Response Relationship, Drug; Enzyme Activation; Fluorometry; Hydrogen-Ion Concentration; Kidney; Opossums; Parathyroid Hormone; Protein Kinases; Sodium; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 1990 |
Aldosterone influences free intracellular calcium in human mononuclear leukocytes in vitro.
Topics: Adolescent; Adult; Aged; Aldosterone; Amiloride; Calcium; Canrenoic Acid; Canrenone; Corticosterone; Cycloheximide; Dactinomycin; Humans; Hydrocortisone; Leukocytes, Mononuclear; Middle Aged | 1990 |
Mechanism of angiotensin II action on proximal tubular transport.
Topics: Amiloride; Angiotensin II; Animals; Biological Transport; Dose-Response Relationship, Drug; Kidney Tubules, Proximal; Male; Protein Kinase C; Rats; Rats, Inbred Strains; Sodium; Tetradecanoylphorbol Acetate | 1990 |
Sodium-dependent, ethylisopropylamiloride-sensitive mechanisms regulate intracellular pH in human vascular smooth muscle.
Topics: Acid-Base Equilibrium; Amiloride; Bicarbonates; Body Fluids; Cells, Cultured; Humans; Intracellular Fluid; Muscle, Smooth, Vascular; Sodium | 1990 |
Amiloride analogs induce the phosphorylation of elongation factor-2 in vascular endothelial cells.
Topics: Amiloride; Animals; Cattle; Cells, Cultured; Endothelium, Vascular; Hydrogen-Ion Concentration; Kinetics; Methionine; Molecular Weight; Peptide Elongation Factor 2; Peptide Elongation Factors; Phosphorylation; Reticulocytes; Ribonucleoproteins | 1990 |
Extracellular ATP stimulates an amiloride-sensitive sodium influx in human lymphocytes.
Topics: Adenosine Triphosphate; Amiloride; Biological Transport; Dose-Response Relationship, Drug; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Membrane Potentials; Sodium; Thymine Nucleotides; Uridine Triphosphate | 1990 |
Regulation of intracellular pH by cultured opossum kidney cells.
Topics: Amiloride; Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Line; Cells, Cultured; Chlorides; Culture Media; Homeostasis; Hydrogen-Ion Concentration; Kidney; Kinetics; Monensin; Opossums; Ouabain; Potassium; Quaternary Ammonium Compounds | 1990 |
Amiloride analogues inhibit proximal tubule metabolism.
Topics: Adenine Nucleotides; Amiloride; Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Ion Channels; Kidney Tubules, Proximal; Nystatin; Ouabain; Oxygen Consumption; Rabbits; Sodium; Sodium-Potassium-Exchanging ATPase | 1986 |
Na-H exchange is a major pathway for Na influx in rat vascular smooth muscle.
Topics: Amiloride; Animals; Aorta, Thoracic; Carrier Proteins; Cells, Cultured; Hydrogen-Ion Concentration; Ion Channels; Muscle, Smooth, Vascular; Ouabain; Potassium; Rats; Rats, Inbred Strains; Sodium; Sodium-Hydrogen Exchangers | 1986 |
Selective inhibition by ethylisopropylamiloride of the positive inotropic effect evoked by low concentrations of ouabain in rat isolated ventricles.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amiloride; Animals; Heart Ventricles; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Ouabain; Rats; Rats, Inbred Strains | 1986 |
Relations among sodium pump inhibition, Na-Ca and Na-H exchange activities, and Ca-H interaction in cultured chick heart cells.
Topics: Amiloride; Animals; Calcium; Cells, Cultured; Cytosol; Drug Interactions; Hydrogen; Hydrogen-Ion Concentration; Ion Channels; Myocardium; Ouabain; Sodium | 1987 |
Sodium-lithium exchange in sarcolemmal vesicles from canine superior mesenteric artery.
Topics: Amiloride; Animals; Biological Transport, Active; Cell Membrane Permeability; Dogs; Female; Ion Channels; Lithium; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Phloretin; Quinidine; Sarcolemma; Sodium | 1988 |
Amiloride and amiloride analogs inhibit Na+/K+-transporting ATPase and Na+-coupled alanine transport in rat hepatocytes.
Topics: Adenosine Triphosphate; Alanine; Amiloride; Animals; Biological Transport; Cell Membrane; Cells, Cultured; Ion Channels; Liver; Male; Ouabain; Rats; Rats, Inbred Strains; Rubidium Radioisotopes; Sodium; Sodium Radioisotopes; Sodium-Potassium-Exchanging ATPase | 1988 |
Stimulation of the Na+/H+ exchanger in human endothelial cells activated by granulocyte- and granulocyte-macrophage-colony-stimulating factor. Evidence for a role in proliferation and migration.
Topics: Amiloride; Carrier Proteins; Cell Division; Cell Movement; Colony-Stimulating Factors; Endothelium, Vascular; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; Sodium; Sodium-Hydrogen Exchangers; Umbilical Veins | 1989 |
Effects of amiloride analogues on the production of prostacyclin by aortic endothelial cells.
Topics: Adenosine Triphosphate; Amiloride; Animals; Aorta, Thoracic; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cattle; Cells, Cultured; Dinoprost; Endothelium, Vascular; Epoprostenol; Hydrogen-Ion Concentration; Radioimmunoassay | 1989 |
Na+/H+ exchange activation mediates the lipopolysaccharide-induced proliferation of human B lymphocytes and is impaired in malignant B-chronic lymphocytic leukemia lymphocytes.
Topics: Aged; Amiloride; B-Lymphocytes; Carrier Proteins; Child; Female; Humans; Hydrogen-Ion Concentration; Interleukin-4; Interleukins; Leukemia, Lymphocytic, Chronic, B-Cell; Lipopolysaccharides; Lymphocyte Activation; Male; Middle Aged; Sodium-Hydrogen Exchangers | 1989 |
Influence of atrial natriuretic factor on 5-(N-ethyl-N-isopropyl)amiloride-sensitive 22Na+ uptake in rabbit aorta.
Topics: Amiloride; Animals; Aorta, Thoracic; Atrial Natriuretic Factor; Cyclic GMP; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Nitroprusside; Phorbol 12,13-Dibutyrate; Rabbits; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface; Sodium; Vasodilation | 1989 |
Regulation of Na+-H+ exchange in normal NIH-3T3 cells and in NIH-3T3 cells expressing the ras oncogene.
Topics: Amiloride; Aminoquinolines; Animals; Biological Transport; Blood; Calcium; Calmodulin; Cell Line; Diglycerides; Enzyme Activation; Fibroblasts; Gallic Acid; Genes, ras; Humans; Inositol Phosphates; Mice; Platelet-Derived Growth Factor; Protein Kinase C; Protons; Sodium; Tetradecanoylphorbol Acetate; Transfection; Trifluoperazine; Urinary Bladder | 1989 |
Agonist-specific role for Na+-H+ antiport in prostaglandin release from microvessel endothelium.
Topics: Adenosine Triphosphate; Amiloride; Animals; Biological Transport; Calcimycin; Carrier Proteins; Cells, Cultured; Coronary Vessels; Dinoprostone; Endothelium, Vascular; Epoprostenol; Fluoresceins; Fluorescent Dyes; Hydrogen-Ion Concentration; Microcirculation; Prostaglandins; Protons; Rabbits; Sodium; Sodium-Hydrogen Exchangers; Thrombin | 1989 |
Blastocoel expansion in the preimplantation mouse embryo: role of extracellular sodium and chloride and possible apical routes of their entry.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Amiloride; Animals; Biological Transport; Blastocyst; Carrier Proteins; Chloride Channels; Chloride-Bicarbonate Antiporters; Chlorides; Cytochalasin D; Cytochalasins; Ectoderm; Epithelium; Kinetics; Membrane Proteins; Mice; Nitrobenzoates; Potassium; Sodium; Sodium Channels; Sodium-Hydrogen Exchangers | 1989 |
[Prevention of reperfusion-induced arrhythmia by Na+/H+ exchange block].
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Hydrogen-Ion Concentration; In Vitro Techniques; Ion Exchange; Myocardial Reperfusion Injury; Myocardium; Rats; Sodium Channels | 1989 |
Potentiation by adrenaline of thrombin-induced elevation of pHi is not essential for synergistic activation of human platelets.
Topics: Amiloride; Blood Platelets; Carrier Proteins; Drug Synergism; Epinephrine; Fluorescence; Humans; Hydrogen-Ion Concentration; Sodium-Hydrogen Exchangers; Thrombin | 1989 |
Sodium-lithium exchange and sodium-proton exchange are mediated by the same transport system in sarcolemmal vesicles from bovine superior mesenteric artery.
Topics: Amiloride; Animals; Carrier Proteins; Cattle; Erythrocytes; Humans; Kinetics; Lithium; Mesenteric Arteries; Muscle, Smooth, Vascular; Sarcolemma; Sodium; Sodium-Hydrogen Exchangers | 1989 |
Intracellular Ca2+ potentiates Na+/H+ exchange and cell differentiation induced by phorbol ester in U937 cells.
Topics: Amiloride; Calcium; Carrier Proteins; Cell Differentiation; Cell Line; Ethers; Flow Cytometry; Humans; Hydrogen-Ion Concentration; Ionomycin; Kinetics; Macrophages; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 1989 |
The Na+/H+ exchange is required for platelet aggregation induced by AVP (arginine-vasopressin).
Topics: Adult; Amiloride; Arginine Vasopressin; Carrier Proteins; Humans; In Vitro Techniques; Middle Aged; Platelet Aggregation; Protons; Sodium; Sodium-Hydrogen Exchangers | 1989 |
Insulin and IGF I receptor-mediated Na+ transport in toad urinary bladders.
Topics: Amiloride; Animals; Binding, Competitive; Bufo marinus; Cell Membrane; Female; Humans; In Vitro Techniques; Insulin; Insulin-Like Growth Factor I; Kinetics; Placenta; Pregnancy; Receptor, Insulin; Receptors, Cell Surface; Receptors, Somatomedin; Recombinant Proteins; Sodium; Somatomedins; Urinary Bladder | 1989 |
Aldosterone induction of electrogenic sodium transport in the apical membrane vesicles of rat distal colon.
Topics: Aldosterone; Amiloride; Animals; Cell Membrane; Colon; Diffusion; Electrochemistry; Fluorescent Antibody Technique; Kinetics; Microscopy, Electron; Potassium; Protons; Rats; Rats, Inbred Strains; Sodium; Sodium Radioisotopes; Valinomycin | 1989 |
The sodium cycle in methanogenesis. CO2 reduction to the formaldehyde level in methanogenic bacteria is driven by a primary electrochemical potential of Na+ generated by formaldehyde reduction to CH4.
Topics: Amiloride; Carbon Dioxide; Carrier Proteins; Euryarchaeota; Formaldehyde; Hydrogen; Methane; Oxidation-Reduction; Salicylanilides; Sodium; Sodium Channels; Sodium-Hydrogen Exchangers | 1989 |
Inhibition of neuronal noradrenaline transport (uptake1) and desipramine binding by amiloride and ethylisopropylamiloride.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Desipramine; Hydrogen-Ion Concentration; Kinetics; Neurons; Norepinephrine; Pheochromocytoma; Sodium; Synaptic Transmission; Tritium | 1989 |
Effects of alpha-adrenergic agonists on intracellular and intramitochondrial pH in rat proximal nephrons.
Topics: Adrenergic alpha-Agonists; Amiloride; Animals; Carrier Proteins; Cytosol; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney Tubules, Proximal; Kinetics; Male; Mitochondria; Nephrons; Prazosin; Rats; Rats, Inbred Strains; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 1989 |
Low-dose glucocorticoids stimulate electroneutral NaCl absorption in rat colon.
Topics: Adrenalectomy; Aldosterone; Amiloride; Androstanols; Animals; Chlorides; Colon; Dexamethasone; Intestinal Absorption; Male; Membrane Potentials; Muscle, Smooth; Rats; Rats, Inbred Strains; Reference Values; Sodium; Sodium Chloride | 1989 |
Phosphorylation-dependent and -independent pathways of platelet aggregation.
Topics: Alkaloids; Amiloride; Calcium; Cytosol; Humans; Phosphorylation; Platelet Aggregation; Protein Kinase C; Staurosporine; Thrombin | 1989 |
Determinants of ammonia entry along the rat proximal tubule during chronic metabolic acidosis.
Topics: Acidosis; Amiloride; Ammonia; Animals; Bicarbonates; Kidney Tubules, Proximal; Perfusion; Rats; Rats, Inbred Strains | 1989 |
Phorbol esters and chemotactic factor induce distinct changes in cytoplasmic Ca2+ and pH in granulocytic like HL60 cells.
Topics: Amiloride; Calcium; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Granulocytes; Humans; Hydrogen-Ion Concentration; Kinetics; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Effect of ethylisopropyl amiloride on intracellular pH regulation in cultured rat astrocytes.
Topics: Amiloride; Animals; Animals, Newborn; Astrocytes; Body Fluids; Cells, Cultured; Hydrogen-Ion Concentration; Intracellular Fluid; Rats; Sodium | 1989 |
Identification of amiloride-sensitive Na+/H+ exchange in rat NB2 node lymphoma cells. Stimulation by 12-O-tetradecanoyl-phorbol-13-acetate.
Topics: Amiloride; Animals; Carrier Proteins; Cell Division; Cell Line; Humans; Hydrogen-Ion Concentration; Lymphoma; Phorbol Esters; Prolactin; Protein Kinase Inhibitors; Rats; Sodium-Hydrogen Exchangers; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1987 |
Amiloride-sensitive Na+/H+ exchange in rat NB2 node lymphoma cells. Stimulation by prolactin and other mitogens.
Topics: Amiloride; Animals; Carrier Proteins; Humans; Hydrogen-Ion Concentration; Lymphoma; Mitogens; Osmotic Pressure; Prolactin; Rats; Sodium; Sodium-Hydrogen Exchangers; Stimulation, Chemical | 1987 |
Evidence for a role for Na+-H+ exchange in activation of human platelets by PAF.
Topics: Amiloride; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Fatty Acids, Unsaturated; Humans; Hydrazines; Indomethacin; Platelet Activating Factor; Platelet Aggregation; Protons; Serotonin; Sodium; Thromboxane A2; Thromboxane B2 | 1987 |
Activation of sodium-proton exchange is not a prerequisite for Ca2+ mobilization and aggregation in human platelets.
Topics: Amiloride; Blood Platelets; Calcium; Carrier Proteins; Humans; Platelet Aggregation; Protons; Sodium; Sodium-Hydrogen Exchangers; Thrombin | 1987 |
Thrombin-induced changes of intracellular [Ca2+] and pH in human platelets. Cytoplasmic alkalinization is not a prerequisite for calcium mobilization.
Topics: Amiloride; Blood Platelets; Calcium; Carrier Proteins; Cytoplasm; Ethers; Humans; Hydrogen-Ion Concentration; Ionomycin; Protein Kinase C; Sodium-Hydrogen Exchangers; Sphingosine; Thrombin | 1988 |
Ca2+ mobilization can occur independent of acceleration of Na+/H+ exchange in thrombin-stimulated human platelets.
Topics: Amiloride; Benzofurans; Blood Platelets; Calcium; Carrier Proteins; Fluoresceins; Fluorescent Dyes; Fura-2; Humans; Hydrogen-Ion Concentration; Nigericin; Sodium-Hydrogen Exchangers; Spectrometry, Fluorescence; Thrombin | 1988 |
LLC-PK1 mutant with increased Na+-H+ exchange and decreased sensitivity to amiloride.
Topics: Amiloride; Animals; Carrier Proteins; Cell Line; Cell Survival; Harmaline; Hydrogen-Ion Concentration; Kinetics; Models, Biological; Mutation; Rubidium; Sodium; Sodium-Hydrogen Exchangers | 1988 |
pH in principal cells of frog skin (Rana pipiens): dependence on extracellular Na+.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Cell Membrane; Dimethyl Sulfoxide; Hydrogen-Ion Concentration; Membrane Potentials; Protons; Rana pipiens; Skin; Skin Physiological Phenomena; Sodium | 1988 |
Role of Na+/H+ exchange in thrombin-induced platelet-activating factor production by human endothelial cells.
Topics: Acetyltransferases; Amiloride; Calcium; Carrier Proteins; Cells, Cultured; Endothelium, Vascular; Humans; Hydrogen-Ion Concentration; Kinetics; Monensin; Platelet Activating Factor; Sodium-Hydrogen Exchangers; Thrombin; Umbilical Veins | 1988 |
Conductive sodium pathway with low affinity to amiloride in LLC-PK1 cells and other epithelia.
Topics: Amiloride; Animals; Cell Line; Cell Membrane; Epithelium; Erythrocyte Membrane; Female; Humans; Kidney Cortex; Kinetics; Male; Membrane Potentials; Microvilli; Rabbits; Rana ridibunda; Rats; Rats, Inbred Strains; Sodium; Sodium Channels; Valinomycin | 1988 |
pH regulation in single glomerular mesangial cells. I. Acid extrusion in absence and presence of HCO3-.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Amiloride; Ammonia; Animals; Bicarbonates; Cells, Cultured; Glomerular Mesangium; Hydrogen-Ion Concentration; Kinetics; Rats; Spectrometry, Fluorescence | 1988 |
Inhibition and labeling of the rat renal Na+/H+-exchanger by an antagonist of muscarinic acetylcholine receptors.
Topics: Acridine Orange; Affinity Labels; Amiloride; Animals; Carrier Proteins; Choline; Diazomethane; Dicyclohexylcarbodiimide; Iodocyanopindolol; Kidney; Lithium; Male; Microvilli; Pindolol; Propranolol; Propylbenzilylcholine Mustard; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Sodium; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase | 1988 |
Inhibition of colonic Na+ transport by amiloride analogues.
Topics: Amiloride; Animals; Biological Transport; Colon; Dexamethasone; Electric Conductivity; Electrophysiology; Epithelium; Female; Kinetics; Rats; Rats, Inbred Strains; Sodium | 1989 |
The role of the Na+/H+ exchange system in the regulation of the internal pH in cultured cardiac cells.
Topics: Amiloride; Ammonia; Animals; Cations; Cells, Cultured; Chick Embryo; Cytoplasm; Hydrogen-Ion Concentration; Myocardium; Potassium; Protons; Sodium | 1985 |
Inhibitors of Na+/H+ exchange block stimulus-provoked arachidonic acid release in human platelets. Selective effects on platelet activation by epinephrine, ADP, and lower concentrations of thrombin.
Topics: Adenosine Diphosphate; Amiloride; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Carrier Proteins; Epinephrine; Humans; Hydrogen-Ion Concentration; Male; Platelet Aggregation; Serotonin; Sodium; Sodium-Hydrogen Exchangers; Thrombin; Thromboxanes | 1985 |
Inhibitors of Na+/H+ exchange block epinephrine- and ADP-induced stimulation of human platelet phospholipase C by blockade of arachidonic acid release at a prior step.
Topics: Adenosine Diphosphate; Amiloride; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Carrier Proteins; Diglycerides; Enzyme Activation; Epinephrine; Humans; Inositol Phosphates; Kinetics; Male; Platelet Aggregation; Sodium-Hydrogen Exchangers; Tritium; Type C Phospholipases | 1986 |
Inhibition of Na+/H+ exchange reduces Ca2+ mobilization without affecting the initial cleavage of phosphatidylinositol 4,5-bisphosphate in thrombin-stimulated platelets.
Topics: Amiloride; Blood Platelets; Calcium; Cytosol; Humans; Hydrogen; Hydrogen-Ion Concentration; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Sodium; Thrombin | 1987 |
pH regulation in single glomerular mesangial cells. II. Na+-dependent and -independent Cl(-)-HCO3- exchangers.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Alanine; Amiloride; Animals; Carrier Proteins; Cations, Divalent; Cells, Cultured; Chloride-Bicarbonate Antiporters; Chlorides; Glomerular Mesangium; Glucose; Hydrogen-Ion Concentration; Kinetics; Membrane Proteins; Rats; Sodium | 1988 |
Activation of Na+/H+ exchange in human platelets stimulated by thrombin and a phorbol ester.
Topics: Amiloride; Biological Transport; Blood Platelets; Cytoplasm; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Ion Exchange; Sodium; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Thrombin | 1987 |
Inhibition by amiloride analogues of Na+-dependent hexose uptake in LLC-PK1/Cl4 cells.
Topics: Amiloride; Animals; Clone Cells; Dose-Response Relationship, Drug; Hexoses; Kidney; Phlorhizin; Sodium | 1987 |
Ethylisopropyl-amiloride: a new and highly potent derivative of amiloride for the inhibition of the Na+/H+ exchange system in various cell types.
Topics: Amiloride; Animals; Carrier Proteins; Cells, Cultured; Chickens; Dose-Response Relationship, Drug; Mice; Pyrazines; Sodium-Hydrogen Exchangers; Structure-Activity Relationship | 1983 |
Na+-HCO3(-) cotransporter and intracellular pH regulation in chicken enterocytes.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Carrier Proteins; Chickens; Digestive System; Homeostasis; Hydrogen-Ion Concentration; Kinetics; Sodium; Sodium-Bicarbonate Symporters; Solutions | 1995 |
Effects of inhibitors of enzymatic and cellular pH-regulating systems on central sympathetic chemosensitivity.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetazolamide; Amiloride; Animals; Autonomic Fibers, Preganglionic; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Cats; Chemoreceptor Cells; Denervation; Diethyl Pyrocarbonate; Female; Hydrogen-Ion Concentration; Male; Medulla Oblongata; Perfusion; Sympathetic Nervous System | 1995 |
pH modulates cAMP-induced increase in Na+ transport across frog skin epithelium.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Biological Transport; Cadmium; Chlorides; Cyclic AMP; Hydrogen-Ion Concentration; Intracellular Fluid; Membrane Potentials; Patch-Clamp Techniques; Potassium; Rana pipiens; Skin; Sodium; Zinc | 1995 |
Product of the steel locus suppresses apoptosis in hemopoietic cells. Comparison with pathways activated by granulocyte macrophage colony-stimulating factor.
Topics: Alkaloids; Amiloride; Animals; Apoptosis; Bone Marrow; Bone Marrow Cells; Catechols; Cell Division; Cell Line; Cell Survival; DNA; DNA Damage; Fusion Proteins, bcr-abl; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Cell Growth Factors; Hematopoietic Stem Cells; Humans; Hydrogen-Ion Concentration; Interleukin-3; Leukemia, Myeloid, Acute; Nitriles; Protein Kinase Inhibitors; Recombinant Proteins; Staurosporine; Stem Cell Factor; Thymidine; Transfection; Tyrphostins | 1994 |
Anti-idiotypic antibodies to delineate epitope specificity of anti-amiloride antibodies.
Topics: Amiloride; Animals; Antibodies; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal; Biological Transport; Cell Line; Chickens; Enzyme-Linked Immunosorbent Assay; Epitopes; Immunoglobulin Idiotypes; Intestine, Small; Microvilli; Sodium; Sodium-Hydrogen Exchangers | 1994 |
Endothelin 1 stimulates Na+,K(+)-ATPase and Na(+)-K(+)-Cl- cotransport through ETA receptors and protein kinase C-dependent pathway in cerebral capillary endothelium.
Topics: Amiloride; Animals; Calcium; Capillaries; Carrier Proteins; Cells, Cultured; Cerebrovascular Circulation; Endothelin Receptor Antagonists; Endothelins; Endothelium, Vascular; Extracellular Space; Potassium; Protein Kinase C; Rats; Receptors, Endothelin; Sodium-Potassium-Chloride Symporters; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate | 1995 |
Endothelin-induced changes in intracellular pH and Ca2+ in coronary smooth muscle: role of Na(+)-H+ exchange.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Calcium; Cells, Cultured; Choline; Coronary Vessels; Endothelins; Hydrogen-Ion Concentration; Kinetics; Meglumine; Muscle, Smooth, Vascular; Sodium; Sodium-Hydrogen Exchangers; Swine | 1995 |
Modification of tumor necrosis factor-alpha (TNF-alpha) production by the Na(+)-dependent HCO3- cotransport in lipopolysaccharide-activated human monocytes.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adjuvants, Immunologic; Amiloride; Bicarbonates; Carrier Proteins; Culture Media; Humans; Hydrogen-Ion Concentration; Kinetics; Lipopolysaccharides; Macrophage Activation; Monocytes; Phloretin; Protein Biosynthesis; Sodium; Sodium-Bicarbonate Symporters; Tumor Necrosis Factor-alpha | 1995 |
Cytoplasmic domain of the ubiquitous Na+/H+ exchanger NHE1 can confer Ca2+ responsiveness to the apical isoform NHE3.
Topics: Amiloride; Amino Acid Sequence; Animals; Binding Sites; Biological Transport; Calcium; Calmodulin; Cell Line; Cytoplasm; Humans; Hydrogen-Ion Concentration; Immunoblotting; Ionomycin; Kinetics; Molecular Sequence Data; Mutagenesis; Rats; Recombinant Fusion Proteins; Second Messenger Systems; Sequence Deletion; Sequence Homology, Amino Acid; Sodium; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Thrombin; Transfection | 1995 |
Three aspartic residues in membrane-spanning regions of Na+/H+ antiporter from Vibrio alginolyticus play a role in the activity of the carrier.
Topics: Amiloride; Aspartic Acid; Base Sequence; Biological Transport; Escherichia coli; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Secondary; Protons; Recombinant Proteins; Sodium; Sodium Cyanide; Sodium-Hydrogen Exchangers; Structure-Activity Relationship; Vibrio | 1995 |
Acid incubation increases NHE-3 mRNA abundance in OKP cells.
Topics: Acids; Amiloride; Amino Acid Sequence; Animals; Base Sequence; Cell Line; Drug Resistance; Hydrogen-Ion Concentration; Kidney; Molecular Probes; Molecular Sequence Data; Oocytes; Opossums; RNA, Messenger; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Xenopus laevis | 1995 |
Regulation of renal Na-HCO3 cotransporter: III. Presence and modulation by glucocorticoids in primary cultures of the proximal tubule.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Carrier Proteins; Cells, Cultured; Dexamethasone; Glucocorticoids; Hydrocortisone; Kidney; Kidney Tubules; Rabbits; Sodium-Bicarbonate Symporters | 1995 |
Mutational analysis of transmembrane histidines in the amiloride-sensitive Na+/H+ exchanger.
Topics: Amiloride; Amino Acids; Animals; Base Sequence; Cell Line; Cimetidine; Diethyl Pyrocarbonate; Dose-Response Relationship, Drug; Histidine; Hydroxylamine; Hydroxylamines; Kinetics; Membranes; Mice; Molecular Probes; Molecular Sequence Data; Mutagenesis, Site-Directed; Sodium-Hydrogen Exchangers | 1995 |
Cloning and expression of a rabbit cDNA encoding a serum-activated ethylisopropylamiloride-resistant epithelial Na+/H+ exchanger isoform (NHE-2).
Topics: Adenocarcinoma; Amiloride; Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Carrier Proteins; Cloning, Molecular; Colonic Neoplasms; DNA; Drug Resistance; Epithelium; Gene Expression; Humans; Intestinal Mucosa; Molecular Sequence Data; Molecular Weight; Organ Specificity; Poly A; Rabbits; Rats; Restriction Mapping; RNA; RNA, Messenger; Sequence Homology, Amino Acid; Sodium; Sodium-Hydrogen Exchangers; Transfection; Tumor Cells, Cultured | 1993 |
Intracellular acidification associated with changes in free cytosolic calcium. Evidence for Ca2+/H+ exchange via a plasma membrane Ca(2+)-ATPase in vascular smooth muscle cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acids; Alkalies; Amiloride; Angiotensin II; Animals; Aorta; Biological Transport; Cadmium; Calcium; Calcium-Transporting ATPases; Cell Membrane; Cytosol; Egtazic Acid; Enzyme Activation; Ionomycin; Male; Muscle, Smooth, Vascular; Protons; Rats; Sarcoplasmic Reticulum | 1995 |
The effect of acute metabolic alkalosis on bicarbonate transport along the loop of Henle. The role of active transport processes and passive paracellular backflux.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acute Disease; Alkalosis; Amiloride; Animals; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Bicarbonates; Biological Transport, Active; Carbon Dioxide; Loop of Henle; Macrolides; Male; Proton-Translocating ATPases; Rats; Rats, Sprague-Dawley | 1994 |
Angiotensin II stimulates sodium-hydrogen exchange in adult rabbit ventricular myocytes.
Topics: Amiloride; Angiotensin II; Animals; Anti-Arrhythmia Agents; Benzopyrans; Calcium; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug; Electric Stimulation; Fluorescent Dyes; Hydrogen-Ion Concentration; Myocardium; Rabbits; Sodium-Hydrogen Exchangers; Stimulation, Chemical | 1995 |
Intracellular pH in vascular smooth muscle: regulation by sodium-hydrogen exchange and multiple sodium dependent HCO3- mechanisms.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Adenosine Triphosphate; Amiloride; Animals; Antiporters; Bicarbonates; Carrier Proteins; Cells, Cultured; Chloride-Bicarbonate Antiporters; Hydrogen-Ion Concentration; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Sodium-Bicarbonate Symporters; Sodium-Hydrogen Exchangers | 1995 |
Role of sodium-hydrogen exchange in the proliferation of immortalised lymphoblasts from patients with essential hypertension and normotensive subjects.
Topics: Amiloride; Anti-Arrhythmia Agents; Cell Cycle; Cell Division; Cell Line; Humans; Hydrogen-Ion Concentration; Hypertension; Lymphocytes; Sodium-Hydrogen Exchangers | 1995 |
Inhibition of sodium-hydrogen exchange reduces infarct size in the isolated rat heart--a protective additive to ischaemic preconditioning.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Male; Myocardial Infarction; Myocardial Ischemia; Myocardium; Perfusion; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers | 1995 |
Stimulation of sarcolemmal sodium-hydrogen exchange in cardiac myocytes as a mediator of the positive inotropic action of alpha 1 adrenergic agonists.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amiloride; Animals; Anti-Arrhythmia Agents; Dioxanes; Hydrogen-Ion Concentration; Myocardial Contraction; Myocardium; Protein Kinase C; Rabbits; Sarcolemma; Sodium-Hydrogen Exchangers; Stimulation, Chemical | 1995 |
Role of Na-H exchangers and vacuolar H+ pumps in intracellular pH regulation in neonatal rat osteoclasts.
Topics: 4-Chloro-7-nitrobenzofurazan; Acid-Base Equilibrium; Amiloride; Animals; Animals, Newborn; Buffers; Cell Membrane; Fluoresceins; Hydrogen-Ion Concentration; Osteoclasts; Proton Pumps; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Sodium; Sodium-Hydrogen Exchangers; Vacuoles | 1995 |
An electrogenic sodium-bicarbonate cotransport in the regulation of myocardial intracellular pH.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Amiloride; Animals; Anti-Arrhythmia Agents; Bicarbonates; Carrier Proteins; Cats; Homeostasis; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Membrane Potentials; Myocardium; Papillary Muscles; Potassium; Sodium; Sodium-Bicarbonate Symporters; Time Factors | 1995 |
Reconstitution of immunopurified alveolar type II cell Na+ channel protein into planar lipid bilayers.
Topics: Adenosine Triphosphate; Amiloride; Animals; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Epithelium; Immunologic Techniques; Lipid Bilayers; Male; Pulmonary Alveoli; Rabbits; Sodium Channels | 1995 |
Ion transport across the early chick embryo: II. Characterization and pH sensitivity of the transembryonic short-circuit current.
Topics: Amiloride; Animals; Blastoderm; Cell Membrane; Chick Embryo; Ectoderm; Electric Conductivity; Electrophysiology; Glucose; Hydrogen-Ion Concentration; Membrane Potentials; Organ Culture Techniques; Phlorhizin; Time Factors | 1994 |
31P NMR and triple quantum filtered 23Na NMR studies of the effects of inhibition of Na+/H+ exchange on intracellular sodium and pH in working and ischemic hearts.
Topics: Acidosis; Amiloride; Animals; Biological Transport, Active; Cardiac Output; Coronary Circulation; Energy Metabolism; Heart Rate; Hydrogen; Hydrogen-Ion Concentration; Ion Transport; Magnetic Resonance Spectroscopy; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Phosphorus Isotopes; Rats; Rats, Sprague-Dawley; Sodium; Sodium Channels; Sodium Isotopes | 1994 |
Na+/H+ exchange and reperfusion arrhythmias: protection by intracoronary infusion of a novel inhibitor.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Circulation; Electrocardiography; Guanidines; Heart Rate; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; Sulfones; Ventricular Fibrillation | 1994 |
Rapid effects of aldosterone on sodium transport in vascular smooth muscle cells.
Topics: Aldosterone; Amiloride; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Inositol 1,4,5-Trisphosphate; Ion Transport; Leukocytes, Mononuclear; Male; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Hydrogen Exchangers | 1995 |
Apoptosis in an interleukin-2-dependent cytotoxic T lymphocyte cell line is associated with intracellular acidification. Role of the Na(+)/H(+)-antiport.
Topics: Amiloride; Animals; Apoptosis; Calcium; Cell Cycle; Cell Line; DNA; Egtazic Acid; Flow Cytometry; Fluorescent Dyes; Interleukin-2; Mice; Sodium-Hydrogen Exchangers; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate | 1995 |
Antitumor activity of nigericin and 5-(N-ethyl-N-isopropyl)amiloride: an approach to therapy based on cellular acidification and the inhibition of regulation of intracellular pH.
Topics: Amiloride; Animals; Cell Hypoxia; Cell Survival; Combined Modality Therapy; Drug Screening Assays, Antitumor; Drug Synergism; Female; Fibrosarcoma; Glucose; Hydralazine; Hydrogen-Ion Concentration; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neoplasm Transplantation; Nigericin; Organoids; Protons; Sarcoma, Experimental | 1994 |
Effect of amiloride on inotropic and toxic actions of ouabain in guinea-pig left atria.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Atrial Function, Left; Drug Synergism; Electric Stimulation; Guinea Pigs; Heart; Heart Atria; Heart Diseases; In Vitro Techniques; Myocardial Contraction; Ouabain; Sodium-Hydrogen Exchangers; Stimulation, Chemical | 1994 |
Lymphocytic intracellular pH and Na+/H+ exchanger activity in hemodialysis patients.
Topics: Adult; Aged; Amiloride; Cell Separation; Female; Flow Cytometry; Fluoresceins; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Sodium Bicarbonate; Sodium-Hydrogen Exchangers; T-Lymphocytes | 1995 |
Intracellular alkalinization suppresses lovastatin-induced apoptosis in HL-60 cells through the inactivation of a pH-dependent endonuclease.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Apoptosis; Cell Cycle; Cell Line; Cycloheximide; DNA, Neoplasm; Endodeoxyribonucleases; Fluoresceins; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Isoquinolines; Kinetics; Leukemia, Promyelocytic, Acute; Lovastatin; Mevalonic Acid; Piperazines; Protein Kinase C; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1995 |
Stimulation of vascular Na(+)-K(+)-ATPase activity by nitric oxide: a cGMP-independent effect.
Topics: Amiloride; Aminoquinolines; Animals; Aorta, Thoracic; Biological Transport; Cyclic GMP; Endothelium, Vascular; Guanylate Cyclase; In Vitro Techniques; Kinetics; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; Ouabain; Rabbits; Rubidium; Sodium-Potassium-Exchanging ATPase | 1994 |
Regulation of intracellular pH in crypt cells from rabbit distal colon.
Topics: Amiloride; Ammonia; Animals; Anti-Bacterial Agents; Buffers; Colon; Female; Fluoresceins; Fluorescent Dyes; Hydrogen-Ion Concentration; Imidazoles; Intracellular Membranes; Macrolides; Male; Quaternary Ammonium Compounds; Rabbits; Sodium | 1994 |
Thermosensitization by increasing intracellular acidity with amiloride and its analogs.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Cell Division; Cell Line; Dose-Response Relationship, Drug; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Mammary Neoplasms, Experimental; Mice; Mice, Inbred A; Structure-Activity Relationship; Tumor Cells, Cultured | 1994 |
Mechanisms of regulatory volume increase in collecting duct cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Biological Transport; Cell Membrane; Chlorides; Female; Hydrogen-Ion Concentration; Kidney Tubules, Collecting; Osmolar Concentration; Rabbits; Sodium; Time Factors; Vasopressins | 1993 |
Sodium channel blockade reduces hypoxic sodium loading and sodium-dependent calcium loading.
Topics: Amiloride; Animals; Benzofurans; Benzothiazoles; Calcium; Calcium Channel Blockers; Cell Separation; Ethers, Cyclic; Fluorescent Dyes; Hypoxia; Lidocaine; Myocardial Contraction; Myocardium; Piperidines; Rats; Sodium; Sodium Channel Blockers; Sodium-Hydrogen Exchangers; Tetrodotoxin; Thiazoles | 1994 |
Regulation of low-amiloride-affinity sodium channels in alveolar type II cells.
Topics: Amiloride; Animals; Binding, Competitive; Cells, Cultured; Electrophysiology; Lectins; Macrophages, Alveolar; Male; Plant Lectins; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Sodium Channels; Terbutaline | 1994 |
Apical membrane Na+/H+ exchange in rat medullary thick ascending limb. pH-dependence and inhibition by hyperosmolality.
Topics: Amiloride; Animals; Buffers; Hydrogen-Ion Concentration; Kidney Medulla; Male; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers | 1994 |
Effects of HMA, an analog of amiloride, on the thermosensitivity of tumors in vivo.
Topics: Amiloride; Animals; Cell Death; Cell Division; Hydrogen-Ion Concentration; Hyperthermia, Induced; Mammary Neoplasms, Experimental; Mice; Mice, Inbred A; Sodium-Hydrogen Exchangers; Spectrometry, Fluorescence; Tumor Cells, Cultured | 1994 |
Renal tubular dopamine outward transfer during Na(+)-H+ exchange activation by alpha 1- and alpha 2-adrenoceptor agonists.
Topics: Adrenergic alpha-Agonists; Amiloride; Animals; Bucladesine; Colforsin; Dopamine; Hydrogen; In Vitro Techniques; Kidney Tubules; Levodopa; Phenylephrine; Phorbol 12,13-Dibutyrate; Quinoxalines; Rats; Sodium; Sphingosine | 1993 |
Human cytomegalovirus infection increases the number of ouabain-binding sites in human fibroblasts.
Topics: Amiloride; Binding Sites; Cell Line; Culture Media; Cytomegalovirus; Fibroblasts; Humans; Ouabain; Sodium-Potassium-Exchanging ATPase; Virus Replication; Water | 1994 |
Intracellular pH recovery during respiratory acidosis in perfused hearts.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetazolamide; Acidosis, Respiratory; Amiloride; Animals; Bicarbonates; Buffers; Female; Ferrets; Hydrogen-Ion Concentration; Intracellular Membranes; Male; Myocardium; Perfusion; Pressure; Sodium-Hydrogen Exchangers; Ventricular Function, Left | 1994 |
Sodium-selective channels in membranes of rat macrophages.
Topics: Amiloride; Animals; Cells, Cultured; Female; Ion Channel Gating; Macrophages, Peritoneal; Male; Membrane Potentials; Rats; Rats, Wistar; Sodium Channel Blockers; Sodium Channels | 1994 |
Characterization and comparison of ion transport across sheep and human airway epithelium.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Acetazolamide; Action Potentials; Amiloride; Animals; Bronchi; Bumetanide; Epithelium; Humans; Ion Transport; Ouabain; Phlorhizin; Sheep; Trachea | 1994 |
Thermosensitization by lowering intracellular pH with 5-(N-ethyl-N-isopropyl) amiloride.
Topics: Amiloride; Animals; Hot Temperature; Hydrogen-Ion Concentration; Mice; Sensitivity and Specificity; Tumor Cells, Cultured | 1993 |
Culture-induced alterations in alveolar type II cell Na+ conductance.
Topics: Amiloride; Animals; Blotting, Western; Cell Membrane; Cells, Cultured; Electric Conductivity; Electrophysiology; Fluorescent Antibody Technique; Male; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Sodium | 1993 |
Comparison between sodium-hydrogen ion and lithium-hydrogen ion exchange in human platelets.
Topics: Amiloride; Antiporters; Biotransformation; Blood Platelets; Cell Membrane; Humans; Hydrogen-Ion Concentration; Lithium; Sodium; Sodium-Hydrogen Exchangers; Thrombin | 1993 |
The Na+/H+ exchanger in transitional cells of the inner ear.
Topics: Amiloride; Animals; Calibration; Cytosol; Ear, Inner; Fluoresceins; Fluorescent Dyes; Gerbillinae; Hydrogen-Ion Concentration; In Vitro Techniques; Sodium-Hydrogen Exchangers; Spectrometry, Fluorescence | 1993 |
Selective cellular acidification and toxicity of weak organic acids in an acidic microenvironment.
Topics: Amiloride; Animals; Butyrates; Butyric Acid; Carboxylic Acids; Cell Hypoxia; Cell Survival; Female; Fluoresceins; Humans; Hydrogen-Ion Concentration; Malonates; Mammary Neoplasms, Experimental; Mice; Propionates; Sarcoma, Experimental; Sodium-Hydrogen Exchangers; Succinates; Succinic Acid; Tumor Cells, Cultured; Urinary Bladder Neoplasms | 1993 |
Chloride dependent intracellular pH increase induced by bepridil in human red blood cells: a possible involvement in correction of ischemic acidosis.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acidosis; Amiloride; Bepridil; Calcium; Carbonic Anhydrases; Chlorides; Erythrocytes; Humans; Hydrogen-Ion Concentration; Intracellular Fluid; Ischemia; Magnetic Resonance Spectroscopy; Membrane Potentials; Methazolamide; Phosphorus; Potassium; Sodium; Sodium-Hydrogen Exchangers | 1993 |
NMR measurements of Na+ and cellular energy in ischemic rat heart: role of Na(+)-H+ exchange.
Topics: Amiloride; Animals; Energy Metabolism; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Male; Myocardial Ischemia; Myocardium; Phosphates; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Hydrogen Exchangers; Ventricular Function | 1993 |
Functional coupling of Na+/H+ and Na+/Ca2+ exchangers in the alpha 1-adrenoreceptor-mediated activation of hepatic metabolism.
Topics: Amiloride; Animals; Calcium; Carrier Proteins; Hydrogen-Ion Concentration; Liver; Membrane Potentials; Monensin; Ouabain; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Sodium; Sodium-Calcium Exchanger; Sodium-Hydrogen Exchangers; Vasopressins | 1994 |
Long-term expression of c-H-ras stimulates Na-H and Na(+)-dependent Cl-HCO3 exchange in NIH-3T3 fibroblasts.
Topics: 3T3 Cells; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Antiporters; Bicarbonates; Biological Transport, Active; Chlorides; Genes, ras; Growth Substances; Hydrogen-Ion Concentration; In Vitro Techniques; Mice; Proto-Oncogene Proteins p21(ras); Sodium | 1994 |
Effect of secretin and inhibitors of HCO3-/H+ transport on the membrane voltage of rat pancreatic duct cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Anti-Arrhythmia Agents; Antiporters; Bicarbonates; Buffers; Chloride-Bicarbonate Antiporters; Electrophysiology; Ethoxzolamide; Female; In Vitro Techniques; Pancreatic Ducts; Rats; Rats, Wistar; Secretin | 1993 |
Different development of apical and basolateral Na-H exchangers in LLC-PK1 renal epithelial cells: characterization by inhibitors and antisense oligonucleotide.
Topics: Amiloride; Animals; Base Sequence; Cell Line; Epithelium; Hydrogen-Ion Concentration; Kidney; Molecular Sequence Data; Oligonucleotides, Antisense; Sodium-Hydrogen Exchangers; Swine | 1994 |
Arachidonic acid abolishes the mitogen-induced increase in cytosolic free Ca2+ and intracellular pHi in rat thymocytes.
Topics: Amiloride; Animals; Arachidonic Acid; Calcium; Concanavalin A; Cytosol; Fluoresceins; Fluorescent Dyes; Fura-2; Hydrogen-Ion Concentration; Mitogens; Phytohemagglutinins; Rats; Rats, Wistar; Thymus Gland | 1993 |
Hoe 694, a new Na+/H+ exchange inhibitor and its effects in cardiac ischaemia.
Topics: Adenosine Triphosphate; Amiloride; Anesthesia; Animals; Blood Platelets; Cattle; Endothelium, Vascular; Erythrocyte Membrane; Female; Glycogen; Guanidines; In Vitro Techniques; Ion Exchange; Male; Myocardial Ischemia; Phosphocreatine; Potassium; Rabbits; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sodium; Sulfones | 1993 |
Studies on the role of sodium on the synthesis of dopamine in the rat kidney.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amiloride; Amphotericin B; Animals; Biological Transport; Carrier Proteins; Dopamine; Extracellular Space; Kidney; Kidney Tubules; Kinetics; Levodopa; Male; Monoamine Oxidase Inhibitors; Ouabain; Rats; Rats, Wistar; Sodium; Sodium-Hydrogen Exchangers | 1993 |
Therapeutic potential of analogues of amiloride: inhibition of the regulation of intracellular pH as a possible mechanism of tumour selective therapy.
Topics: Amiloride; Animals; Carrier Proteins; Cell Survival; Cricetinae; Cricetulus; Fluorometry; Humans; Hydrogen-Ion Concentration; Intracellular Fluid; Mice; Neoplasms, Experimental; Sodium; Sodium Radioisotopes; Sodium-Hydrogen Exchangers; Tumor Cells, Cultured | 1993 |
Kinetic characterization of Na+/H+ antiport of Plasmodium falciparum membrane.
Topics: Amiloride; Animals; Carrier Proteins; Cell Membrane; Culture Media; Cytoplasm; Hydrogen; Hydrogen-Ion Concentration; Kinetics; Plasmodium falciparum; Sodium; Sodium-Hydrogen Exchangers | 1993 |
Intracellular pH regulation in isolated myocytes from adult rat heart in HCO3(-)-containing and HCO3(-)-free media.
Topics: Amiloride; Animals; Benzenesulfonates; Bicarbonates; Carrier Proteins; Cells, Cultured; Fluorometry; Hydrogen-Ion Concentration; Intracellular Fluid; Isothiocyanates; Myocardium; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; Thiocyanates | 1993 |
Structure-activity relations of amiloride derivatives, acting as antagonists of cation binding on Na+/K(+)-ATPase.
Topics: Amiloride; Animals; Binding Sites; Binding, Competitive; Cations; Guanidine; Guanidines; Hydrogen-Ion Concentration; Kidney Medulla; Protein Conformation; Rubidium; Sodium-Potassium-Exchanging ATPase; Structure-Activity Relationship; Swine; Temperature | 1993 |
Sodium-dependent antiporters in choroid plexus epithelial cultures from rabbit.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Ammonium Chloride; Animals; Antiporters; Bicarbonates; Carrier Proteins; Cells, Cultured; Chlorides; Choroid Plexus; Epithelium; Hydrogen-Ion Concentration; Male; Rabbits; Sodium | 1993 |
An epithelial high-affinity amiloride-binding site, different from the Na+ channel.
Topics: Aldosterone; Amiloride; Animals; Binding Sites; Binding, Competitive; Bufo marinus; Cell Membrane; Chickens; Colon; Epithelium; Intestine, Large; Kinetics; Sodium; Sodium Channels; Sodium, Dietary; Urinary Bladder | 1993 |
Effects of formate and oxalate on chloride absorption in rat distal tubule.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Absorption; Amiloride; Animals; Anti-Arrhythmia Agents; Biological Transport; Carrier Proteins; Chlorides; Formates; Kidney Tubules, Distal; Male; Oxalates; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers | 1993 |
Changes in cytoplasmic pH in platelets activated through the high- and moderate-affinity receptor pathways by highly purified human alpha-thrombin.
Topics: Amiloride; Blood Platelets; Cytoplasm; Humans; Hydrogen-Ion Concentration; Platelet Activation; Receptors, Cell Surface; Receptors, Thrombin; Thrombin | 1993 |
5-(N-Ethyl-N-isopropyl)amiloride sensitive Na+ currents in intact fetal distal lung epithelial cells.
Topics: Adenine; Amiloride; Animals; Anti-Arrhythmia Agents; Cell Membrane; Epithelium; Female; Fetus; Lung; Nystatin; Pregnancy; Pulmonary Alveoli; Rats; Rats, Wistar; Sodium Channels | 1993 |
Renal bicarbonate reabsorption in the rat. IV. Bicarbonate transport mechanisms in the early and late distal tubule.
Topics: Acid-Base Equilibrium; Amiloride; Animals; Bicarbonates; Biological Transport, Active; Blood Chemical Analysis; Chlorides; In Vitro Techniques; Kidney Concentrating Ability; Kidney Tubules, Distal; Male; Perfusion; Potassium; Protons; Rats; Rats, Sprague-Dawley; Urine | 1993 |
Na+/H+ exchange activity induced by thrombin is not inhibited by protein kinase inhibitors, staurosporine, K-252a, H-7 and sphingosine, in human platelets.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amiloride; Blood Platelets; Carbazoles; Carrier Proteins; Humans; Hydrogen; Indole Alkaloids; Isoquinolines; Phosphorylation; Piperazines; Protein Kinase C; Protein Processing, Post-Translational; Sodium; Sodium-Hydrogen Exchangers; Sphingosine; Staurosporine; Thrombin | 1993 |
Glucocorticoids stimulate Na+/H+ antiporter in OKP cells.
Topics: Amiloride; Animals; Carrier Proteins; Cell Line; Cycloheximide; Dexamethasone; Drug Resistance; Glucocorticoids; Hydrogen-Ion Concentration; Kidney; Sodium-Hydrogen Exchangers | 1993 |
Na(+)-H+ exchanger in isolated epithelial tracheal cells from sheep. Involvement in tracheal proton secretion.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Carrier Proteins; Dose-Response Relationship, Drug; Epithelial Cells; Epithelium; Fluoresceins; Fluorescence; Hydrogen-Ion Concentration; Protons; Sheep; Sodium; Sodium-Hydrogen Exchangers; Trachea | 1993 |
Suppression of neointimal thickening and smooth muscle cell proliferation after arterial injury in the rat by inhibitors of Na(+)-H+ exchange.
Topics: Amiloride; Animals; Arteries; Carrier Proteins; Catheterization; Cell Division; Guanidines; Male; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Sulfones; Wounds, Nonpenetrating | 1993 |
Na(+)-H+ exchange inhibitors decrease neointimal formation after rat carotid injury. Effects on smooth muscle cell migration and proliferation.
Topics: Amiloride; Animals; Carotid Arteries; Carotid Artery Injuries; Carrier Proteins; Catheterization; Cell Division; Cell Movement; Male; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Wounds, Nonpenetrating | 1993 |
Kinetics of inactivation of the F1Fo ATPase of Propionigenium modestum by dicyclohexylcarbodiimide in relationship to H+ and Na+ concentration: probing the binding site for the coupling ions.
Topics: Adenosine Triphosphate; Amiloride; Bacteria, Anaerobic; Binding Sites; Binding, Competitive; Dicyclohexylcarbodiimide; Hydrogen-Ion Concentration; Kinetics; Proton-Translocating ATPases; Protons; Sodium | 1993 |
On the role of intracellular concentration of Ca2+ and H+ in thymocyte death after irradiation.
Topics: Amiloride; Animals; Antiporters; Biological Transport; Calcium; Calmodulin; Cell Death; Concanavalin A; DNA Damage; Hydrogen-Ion Concentration; Imidazoles; Male; Radiation Injuries, Experimental; Rats; Rats, Wistar; Thymus Gland; Time Factors | 1993 |
Mechanisms of HCl-induced lowering of intracellular pH in rabbit esophageal epithelial cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Anti-Arrhythmia Agents; Antiporters; Cells, Cultured; Chloride-Bicarbonate Antiporters; Cytophotometry; Epithelial Cells; Epithelium; Esophagus; Fluoresceins; Hydrochloric Acid; Hydrogen-Ion Concentration; Rabbits; Sodium; Sodium-Hydrogen Exchangers; Time Factors | 1993 |
Intracellular pH regulation in single cultured astrocytes from rat forebrain.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Ammonia; Animals; Animals, Newborn; Anti-Arrhythmia Agents; Astrocytes; Bicarbonates; Cells, Cultured; Fluorescent Dyes; Hydrogen-Ion Concentration; Potassium; Prosencephalon; Rats; Sodium; Sodium-Hydrogen Exchangers; Solutions | 1993 |
Amiloride and 5-(N-ethyl-N-isopropyl) amiloride inhibit medium acidification and glucose metabolism by the fission yeast Schizosaccharomyces pombe.
Topics: Amiloride; Culture Media; Dose-Response Relationship, Drug; Glucose; Glycolysis; Hydrogen-Ion Concentration; Schizosaccharomyces | 1993 |
Leu143 in the putative fourth membrane spanning domain is critical for amiloride inhibition of an epithelial Na+/H+ exchanger isoform (NHE-2).
Topics: Amiloride; Amino Acid Sequence; Animals; Carrier Proteins; Cloning, Molecular; Cricetinae; Cricetulus; Fibroblasts; Kinetics; Leucine; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Rabbits; Recombinant Proteins; Sodium-Hydrogen Exchangers; Transfection | 1993 |
Angiotensin II and angiotensin-(1-7) effects on free cytosolic sodium, intracellular pH, and the Na(+)-H+ antiporter in vascular smooth muscle.
Topics: Amiloride; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Anti-Arrhythmia Agents; Cells, Cultured; Cytosol; Hydrogen-Ion Concentration; Intracellular Membranes; Male; Muscle, Smooth, Vascular; Ouabain; Peptide Fragments; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Hydrogen Exchangers | 1996 |
[Effect of inhibitors of lipoxygenase oxidation of arachidonic acid and phenofluorazole on rat thymocyte cytoplasmic pH and on the change of this parameter induced by concanavalin A].
Topics: Amiloride; Animals; Arachidonic Acid; Benzimidazoles; Concanavalin A; Cytoplasm; Gossypol; Hydrogen-Ion Concentration; Kinetics; Lipoxygenase Inhibitors; Masoprocol; Oxidation-Reduction; Rats; Sodium-Hydrogen Exchangers; Thymus Gland | 1992 |
The relationship between intracellular pH and heat sensitivity in a thermoresistant cell line.
Topics: Amiloride; Animals; Antiporters; Bicarbonates; Cell Line; Chloride-Bicarbonate Antiporters; Hot Temperature; Hydrogen-Ion Concentration; Mice; Sodium-Hydrogen Exchangers | 1996 |
Identification of a sodium-bicarbonate symport in human platelets.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Amiloride; Bicarbonates; Biological Transport; Blood Platelets; Carrier Proteins; Chlorides; Humans; Hydrogen-Ion Concentration; Potassium; Sodium; Sodium-Bicarbonate Symporters | 1996 |
Basolateral membrane Na+/H+ exchange enhances HCO3- absorption in rat medullary thick ascending limb: evidence for functional coupling between basolateral and apical membrane Na+/H+ exchangers.
Topics: Absorption; Amiloride; Animals; Bicarbonates; Cell Membrane; Diuretics; Epithelium; In Vitro Techniques; Kidney Medulla; Kidney Tubules; Kinetics; Male; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Hydrogen Exchangers | 1995 |
Differential regulation of Na+-K+-ATPase gene expression by corticosteriods in vascular smooth muscle cells.
Topics: Adrenal Cortex Hormones; Aldosterone; Amiloride; Analysis of Variance; Animals; Aorta, Thoracic; Cells, Cultured; Dexamethasone; Gene Expression Regulation, Enzymologic; Kinetics; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase; Spironolactone | 1996 |
EGF modulation of Na+/H+ antiport in rat hepatocytes: different sensitivity in adult and fetal cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Cells, Cultured; Enzyme Inhibitors; Epidermal Growth Factor; Fetus; Fluoresceins; Fluorescent Dyes; GTP-Binding Proteins; Hydroquinones; Kinetics; Liver; Ouabain; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 1996 |
The chronic administration of drugs that inhibit the regulation of intracellular pH: in vitro and anti-tumour effects.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Antineoplastic Agents; Antiporters; Bicarbonates; Cell Line; Cell Survival; Chloride-Bicarbonate Antiporters; Chlorides; Female; Fibrosarcoma; Hydralazine; Hydrogen-Ion Concentration; Kinetics; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Nigericin; Sarcoma, Experimental; Sodium-Hydrogen Exchangers; Tumor Cells, Cultured | 1996 |
Evidence for involvement of a zymogen granule Na+/H+ exchanger in enzyme secretion from rat pancreatic acinar cells.
Topics: Adenine Nucleotides; Amiloride; Amylases; Animals; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cations, Monovalent; Cytoplasmic Granules; Electric Conductivity; Hydrogen-Ion Concentration; Intracellular Membranes; Kinetics; Lithium; Magnesium; Male; Membrane Potentials; Pancreas; Rats; Rats, Wistar; Sodium; Sodium-Hydrogen Exchangers; Valinomycin | 1996 |
Regulation of Na-K-ATPase activity in the proximal tubule: role of the protein kinase C pathway and of eicosanoids.
Topics: Amiloride; Animals; Dopamine; Eicosanoids; Enzyme Inhibitors; Estrenes; Homeostasis; Indomethacin; Kidney Tubules, Proximal; Kinetics; Male; Masoprocol; Models, Biological; Naphthalenes; Neomycin; Nystatin; Oxazines; Parathyroid Hormone; Peptide Fragments; Protein Kinase C; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Teriparatide; Type C Phospholipases | 1996 |
Delineation of transmembrane domains of the Na+/H+ exchanger that confer sensitivity to pharmacological antagonists.
Topics: Amiloride; Animals; Biological Transport; Cimetidine; DNA, Complementary; Enzyme Inhibitors; Guanidines; Kinetics; Ligands; Membrane Glycoproteins; Rats; Recombinant Fusion Proteins; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Structure-Activity Relationship; Sulfones | 1996 |
Stimulation of human cheek cell Na+/H+ antiporter activity by saliva and salivary electrolytes: amplification by nigericin.
Topics: Adult; Amiloride; Cheek; Electrolytes; Gramicidin; Humans; In Vitro Techniques; Ionophores; Kinetics; Mouth Mucosa; Nigericin; Potassium; Saliva; Sodium; Sodium-Hydrogen Exchangers; Valinomycin | 1996 |
Characterization of Na+/H+ exchange activity in cultured rat hippocampal astrocytes.
Topics: Amiloride; Animals; Animals, Newborn; Astrocytes; Bicarbonates; Cell Membrane; Cells, Cultured; Gene Expression; Hippocampus; Hydrogen-Ion Concentration; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers | 1996 |
Angiotensin II stimulates sodium-dependent proton extrusion in perfused ferret heart.
Topics: Alkalosis; Amiloride; Angiotensin II; Animals; Bicarbonates; Female; Ferrets; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Perfusion; Pressure; Protons; Sodium; Ventricular Function, Left | 1996 |
Mechanisms of stimulation of proximal tubule chloride transport by formate and oxalate.
Topics: Amiloride; Animals; Biological Transport; Chlorides; Formates; Kidney Tubules, Proximal; Male; Oxalates; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Sulfates | 1996 |
Mechanism of negative lusitropic effect of alpha 1-adrenoceptor stimulation in cat papillary muscles.
Topics: Actin Cytoskeleton; Amiloride; Animals; Anti-Arrhythmia Agents; Calcium; Cats; Hydrogen-Ion Concentration; In Vitro Techniques; Intracellular Membranes; Myocardial Contraction; Papillary Muscles; Phenylephrine; Protein Kinase C; Receptors, Adrenergic, alpha | 1996 |
Vestibular dark cells contain the Na+/H+ exchanger NHE-1 in the basolateral membrane.
Topics: Amiloride; Animals; Basilar Membrane; Cell Size; Corpus Striatum; Diuretics; Epithelium; Fluoresceins; Fluorescent Dyes; Fluorometry; Gerbillinae; Guanidines; Hydrogen-Ion Concentration; Propionates; Sodium-Hydrogen Exchangers; Structure-Activity Relationship; Sulfones; Vestibule, Labyrinth | 1996 |
Intracellular pH in adipocytes: effects of free fatty acid diffusion across the plasma membrane, lipolytic agonists, and insulin.
Topics: Adipocytes; Amiloride; Animals; Cell Membrane; Cells, Cultured; Colforsin; Diffusion; Fatty Acids, Nonesterified; Fluoresceins; Fluorescent Dyes; Hydrogen-Ion Concentration; Insulin; Isoproterenol; Kinetics; Lipolysis; Male; Models, Biological; Norepinephrine; Rats; Rats, Sprague-Dawley; Serum Albumin, Bovine; Sodium; Time Factors | 1996 |
Rapid activation of Na+/H+ exchange by aldosterone in renal epithelial cells requires Ca2+ and stimulation of a plasma membrane proton conductance.
Topics: Aldosterone; Amiloride; Animals; Calcium; Cell Membrane; Clone Cells; Dogs; Electric Conductivity; Epithelium; Hydrogen-Ion Concentration; Kidney; Kinetics; Models, Biological; Sodium | 1996 |
The relationship between thermosensitivity and intracellular pH in cells deficient in Na+/H+ antiport function.
Topics: Amiloride; Animals; Cell Line; Cell Survival; Cricetinae; Hot Temperature; Hydrogen-Ion Concentration; Hyperthermia, Induced; Sodium Bicarbonate; Sodium-Hydrogen Exchangers | 1996 |
The effects of sodium-calcium exchange inhibitors on protein loss associated with the calcium paradox of the isolated Langendorff perfused guinea-pig heart.
Topics: Amiloride; Amines; Animals; Bepridil; Calcium; Calcium Channel Blockers; Calcium Channels; Carrier Proteins; Enzyme Inhibitors; Guinea Pigs; In Vitro Techniques; Isradipine; Male; Manganese; Myocardium; Myoglobin; Nickel; Perfusion; Sodium-Calcium Exchanger | 1996 |
Okadaic acid induces cellular hypertrophy in AKR-2B fibroblasts: involvement of the p70S6 kinase in the onset of protein and rRNA synthesis.
Topics: Adenine Nucleotides; Amiloride; Animals; Becaplermin; CDC2 Protein Kinase; CDC2-CDC28 Kinases; Cell Line; Cell Size; Chloride Channels; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Gene Expression Regulation; Guanosine Triphosphate; Mice; Mice, Inbred AKR; Nitrobenzoates; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Platelet-Derived Growth Factor; Polyenes; Protein Biosynthesis; Protein Serine-Threonine Kinases; Proteins; Proto-Oncogene Proteins c-sis; Ribosomal Protein S6 Kinases; RNA, Ribosomal; Signal Transduction; Sirolimus; Sodium-Hydrogen Exchangers | 1996 |
Activation of Na+/H+ exchanger is not involved in the PDGF-BB-induced DNA-synthesis in vascular smooth muscle cells.
Topics: Amiloride; Animals; Aorta, Thoracic; Becaplermin; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Guanidines; Hydrogen-Ion Concentration; Kinetics; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Rats; Rats, Inbred WKY; Recombinant Proteins; Sodium; Sodium-Hydrogen Exchangers; Sulfones | 1996 |
Protective effect of the sodium/hydrogen exchange inhibitors during global low-flow ischemia.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Cardiac Output; Energy Metabolism; Guanidines; Heart; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; Sulfones | 1996 |
Reversal of doxorubicin resistance by the amiloride analogue EIPA in multidrug resistant human colon carcinoma cells.
Topics: Adenocarcinoma; Amiloride; Anti-Arrhythmia Agents; Antibiotics, Antineoplastic; Cell Division; Colonic Neoplasms; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Tumor Cells, Cultured; Verapamil | 1996 |
Growth phenotype of cultured skin fibroblasts from IDDM patients with and without nephropathy and overactivity of the Na+/H+ antiporter.
Topics: Adult; Albuminuria; Amiloride; Anti-Arrhythmia Agents; Cell Division; Cells, Cultured; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Female; Fibroblasts; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Phenotype; Skin; Sodium-Hydrogen Exchangers; Thymidine | 1996 |
Activation of water-responsive laryngeal afferents: role of epithelial ion transport.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Afferent Pathways; Amiloride; Animals; Bumetanide; Calcium Channel Blockers; Cats; Chloride Channels; Enzyme Inhibitors; Epithelium; Ion Transport; Laryngeal Nerves; Models, Biological; ortho-Aminobenzoates; Ouabain; Sodium; Sodium-Potassium-Exchanging ATPase; Water | 1996 |
Intracellular pH regulation in chicken enterocytes: the importance of extracellular pH.
Topics: Acids; Amiloride; Animals; Carrier Proteins; Chickens; Extracellular Space; Hydrogen; Hydrogen-Ion Concentration; Intestinal Mucosa; Intestines; Intracellular Membranes; Potassium; Sodium; Sodium-Bicarbonate Symporters | 1995 |
Study of nonspecific cation channel coupled to P2z purinergic receptors using an acid load technique.
Topics: Amiloride; Animals; Cations; Fluoresceins; Fluorescent Dyes; Hydrogen-Ion Concentration; Ion Channels; Ion Transport; Male; Rats; Rats, Wistar; Receptors, Purinergic P2; Submandibular Gland | 1996 |
Identification of a chloroquine importer in Plasmodium falciparum. Differences in import kinetics are genetically linked with the chloroquine-resistant phenotype.
Topics: Amiloride; Animals; Binding, Competitive; Biological Transport; Chloroquine; Crosses, Genetic; Drug Resistance; Erythrocytes; Humans; Kinetics; Phenotype; Plasmodium falciparum; Sodium-Hydrogen Exchangers; Temperature | 1997 |
Pharmacological differentiation of synergistic contribution of L-type Ca2+ channels and Na+/H+ exchange to the positive inotropic effect of phenylephrine, endothelin-3 and angiotensin II in rabbit ventricular myocardium.
Topics: Amiloride; Angiotensin II; Animals; Calcium Channels; Carrier Proteins; Endothelin-3; Male; Myocardial Contraction; Phenylephrine; Rabbits; Receptors, Adrenergic, alpha-1; Sodium-Calcium Exchanger; Sodium-Hydrogen Exchangers; Stimulation, Chemical; Verapamil | 1997 |
The coupling between intracellular pH, ion transport, and chemosensory discharge.
Topics: Amiloride; Animals; Biological Transport, Active; Carbon Dioxide; Carotid Body; Carrier Proteins; Cats; Cell Hypoxia; Glossopharyngeal Nerve; Hydrogen-Ion Concentration; Intracellular Fluid; Ion Transport; Nerve Tissue Proteins; Nicotine; Oxygen; Signal Transduction; Sodium; Sodium Cyanide; Sodium-Calcium Exchanger; Sodium-Hydrogen Exchangers | 1996 |
Intracellular pH regulation in cultured human pleural mesothelial cells.
Topics: Amiloride; Anti-Arrhythmia Agents; Buffers; Cells, Cultured; Epithelium; Humans; Hydrogen-Ion Concentration; Ion Exchange; Pleura; Sodium Bicarbonate; Sodium-Hydrogen Exchangers | 1997 |
Functional properties of cultured endothelial cells derived from large microvessels of human brain.
Topics: Amiloride; Carrier Proteins; Cell Division; Cells, Cultured; Cerebrovascular Circulation; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Humans; Inositol 1,4,5-Trisphosphate; Microcirculation; Ouabain; Potassium; Sodium-Potassium-Chloride Symporters; Sodium-Potassium-Exchanging ATPase; Staurosporine; Tetradecanoylphorbol Acetate; Thymidine | 1997 |
Mechanisms of pHi recovery from NH4Cl-induced acidosis in anoxic isolated turtle heart: a 31P-NMR study.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acidosis; Amiloride; Ammonium Chloride; Animals; Bicarbonates; Buffers; Carbon Dioxide; Female; Hydrogen; Hydrogen-Ion Concentration; Hypoxia; In Vitro Techniques; Intracellular Membranes; Magnetic Resonance Spectroscopy; Male; Myocardium; Phosphorus; Sodium; Temperature | 1997 |
Amylin stimulates proximal tubular sodium transport and cell proliferation in the rat kidney.
Topics: Absorption; Amiloride; Amyloid; Animals; Autoradiography; Biological Transport; Body Fluids; Capillaries; Cell Division; Islet Amyloid Polypeptide; Kidney; Kidney Tubules, Proximal; Mitogens; Perfusion; Punctures; Rats; Rats, Sprague-Dawley; Sodium | 1997 |
A 5-lipoxygenase inhibitor at micromolar concentration raises intracellular calcium in U937 cells prior to their physiologic cell death.
Topics: Amiloride; Apoptosis; Calcium; Cell Survival; DNA; Fluoresceins; Fura-2; Humans; Hydrogen-Ion Concentration; Indoles; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lipoxygenase Inhibitors; Male; Prostate; Trypsin; Tumor Cells, Cultured | 1997 |
Regulation of mu-opioid receptor in neural cells by extracellular sodium.
Topics: Adenylyl Cyclase Inhibitors; Amiloride; Cyclic AMP; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Extracellular Space; Humans; Intracellular Membranes; Monensin; Naltrexone; Neurons; Osmolar Concentration; Ouabain; Receptors, Opioid, mu; Sodium; Tumor Cells, Cultured | 1997 |
Identification of cytoplasmic subdomains that control pH-sensing of the Na+/H+ exchanger (NHE1): pH-maintenance, ATP-sensitive, and flexible loop domains.
Topics: Adenosine Triphosphate; Amiloride; Anti-Arrhythmia Agents; Binding Sites; Calcium; Calmodulin; Cells, Cultured; Cytoplasm; Humans; Hydrogen-Ion Concentration; Ionomycin; Ionophores; Kinetics; Protein Structure, Secondary; Sequence Deletion; Sodium; Sodium-Hydrogen Exchangers; Thrombin | 1997 |
beta-Carotene effectively scavenges toxic nitrogen oxides: nitrogen dioxide and peroxynitrous acid.
Topics: Amiloride; Ascorbic Acid; beta Carotene; Docosahexaenoic Acids; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Nitrates; Nitrogen Dioxide; Vitamin E | 1997 |
Cyclic nucleotide-gated cation channels mediate sodium absorption by IMCD (mIMCD-K2) cells.
Topics: Amiloride; Amino Acid Sequence; Animals; Biological Transport, Active; Calcium; Clone Cells; Cyclic GMP; Diltiazem; Ion Channel Gating; Ion Channels; Kidney Medulla; Kidney Tubules, Collecting; Magnesium; Membrane Potentials; Mice; Molecular Sequence Data; Nucleotides, Cyclic; Patch-Clamp Techniques; Sodium; Sodium Channels | 1997 |
Differing mechanisms of stimulation of Na+ absorption in rabbit proximal colon.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Bicarbonates; Cell Polarity; Colon; Electrophysiology; Epinephrine; Hydrogen-Ion Concentration; Intestinal Absorption; Male; Rabbits; Sodium; Sodium-Hydrogen Exchangers | 1997 |
Mechanisms and sequelae of increased alveolar fluid clearance in hyperoxic rats.
Topics: Amiloride; Animals; Dextrans; Hyperoxia; Lung; Lung Injury; Male; Pulmonary Alveoli; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Sodium; Sodium Channels; Water-Electrolyte Balance | 1997 |
Intracellular pH and heat sensitivity in two human cancer cell lines.
Topics: Amiloride; Antiporters; Breast Neoplasms; Cell Survival; Female; Humans; Hydrogen-Ion Concentration; Hyperthermia, Induced; Ion Transport; Nasopharyngeal Neoplasms; Protons; Sodium Channels; Tumor Cells, Cultured | 1997 |
Insulin-like growth factor I stimulates apical sodium/hydrogen exchange in human proximal tubule cells.
Topics: Adult; Amiloride; Cell Division; Cells, Cultured; Culture Media, Serum-Free; DNA; Female; Fluoresceins; Fluorescent Dyes; Guanidines; Humans; Insulin-Like Growth Factor I; Kidney Tubules, Proximal; Kinetics; Male; Middle Aged; Sodium; Sodium-Hydrogen Exchangers; Spectrometry, Fluorescence; Sulfones; Thymidine | 1997 |
Na+-H+ exchange and intracellular pH regulation in colonocytes from the chick.
Topics: Amiloride; Animals; Cell Membrane; Cells, Cultured; Chickens; Colon; Fluoresceins; Fluorescent Dyes; Hydrogen-Ion Concentration; Sodium-Hydrogen Exchangers | 1997 |
Short-term inhibition of the Na-H exchanger limits acidosis and reduces ischemic injury in the rat heart.
Topics: Acidosis; Adenosine Triphosphate; Amiloride; Ammonium Chloride; Animals; Anti-Arrhythmia Agents; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Male; Myocardial Ischemia; Myocardium; Perfusion; Phosphocreatine; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Time Factors | 1997 |
Calcitonin activates an Na(+)-independent HCO3(-)-dependent pathway in the rabbit distal convoluted tubule.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Bicarbonates; Calcitonin; Carbon Dioxide; Chlorides; Cyclic AMP; Ethylmaleimide; Glutamine; Homeostasis; Hydrogen-Ion Concentration; Imidazoles; In Vitro Techniques; Ketoglutaric Acids; Kidney Tubules, Distal; Male; Microscopy, Fluorescence; Quaternary Ammonium Compounds; Rabbits; Sodium; Sodium-Hydrogen Exchangers | 1997 |
Anoxia-induced depolarization in CA1 hippocampal neurons: role of Na+-dependent mechanisms.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Diuretics; Electrophysiology; Hippocampus; Hypoxia, Brain; Membrane Potentials; Neurons; Oxygen; Rats; Rats, Sprague-Dawley; Sodium; Sodium Channels; Tetrodotoxin | 1997 |
Ethylisopropylamiloride diminishes changes in intracellular Na, Ca and pH in ischemic newborn myocardium.
Topics: Adenosine Triphosphate; Age Factors; Amiloride; Animals; Animals, Newborn; Anti-Arrhythmia Agents; Calcium; Creatine Kinase; Heart; Hydrogen; Hydrogen-Ion Concentration; Ion Channel Gating; Ion Transport; Magnetic Resonance Spectroscopy; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Phosphates; Rabbits; Sodium; Sodium-Hydrogen Exchangers | 1997 |
[A study of the mechanism of lidocaine and befol effects on Na-exchange in normal cardiomyocytes and in the experimental model of hypoxia in vitro].
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Benzamides; Benzofurans; Cell Hypoxia; Cells, Cultured; Enzyme Inhibitors; Heart; Lidocaine; Morpholines; Myocardium; Ouabain; Rats; Sodium; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase; Spectrometry, Fluorescence | 1996 |
A study of the Na+/H+ antiport in the archaeon Methanobacterium thermoautotrophicum strain delta H.
Topics: Amiloride; Calcium; Dicyclohexylcarbodiimide; Egtazic Acid; Hydrogen; Hydrogen-Ion Concentration; Kinetics; Magnesium; Membrane Potentials; Methanobacterium; Sodium; Sodium-Hydrogen Exchangers; Temperature | 1997 |
Intracellular pH regulation in the rabbit cortical collecting duct A-type intercalated cell.
Topics: Amiloride; Animals; Anti-Bacterial Agents; Enzyme Inhibitors; Female; Homeostasis; Hydrogen-Ion Concentration; Imidazoles; In Vitro Techniques; Intracellular Fluid; Kidney Cortex; Kidney Tubules, Collecting; Kinetics; Macrolides; Perfusion; Proton Pump Inhibitors; Proton-Translocating ATPases; Rabbits; Sodium | 1997 |
Nonneuronal dopamine.
Topics: Adrenergic alpha-Agonists; Amiloride; Animals; Benserazide; Biological Transport; Brimonidine Tartrate; Catechol O-Methyltransferase; Dopamine; Kidney; Kidney Cortex; Kidney Tubules; Levodopa; Models, Biological; Monoamine Oxidase; Phenylephrine; Quinoxalines; Sodium-Hydrogen Exchangers | 1998 |
Analysis of the distribution of Na+/H+ exchanger isoforms among the plasma membrane subfractions of bovine kidney cortex: reevaluation of methods for fractionating the brush-border and the basolateral membranes.
Topics: Amiloride; Amino Acid Sequence; Animals; Antibodies; Antibody Formation; Antibody Specificity; Basement Membrane; Cattle; Cell Fractionation; Cell Membrane; Centrifugation, Density Gradient; Cross Reactions; Humans; Isomerism; Kidney Cortex; Microvilli; Molecular Sequence Data; Rabbits; Sensitivity and Specificity; Sequence Homology, Amino Acid; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase; Subcellular Fractions | 1997 |
Amiloride analog stimulation of short-circuit current in larval frog skin epithelium.
Topics: Amiloride; Animals; In Vitro Techniques; Ion Channels; Ion Transport; Larva; Nystatin; Rana catesbeiana; Skin; Structure-Activity Relationship | 1997 |
H+ transporters in the main excretory duct of the mouse mandibular salivary gland.
Topics: Amiloride; Ammonium Chloride; Animals; Anti-Arrhythmia Agents; Antiporters; Bicarbonates; Biological Transport; Buffers; Carrier Proteins; Chloride-Bicarbonate Antiporters; Chlorides; Diuretics; Fluoresceins; Fluorescent Dyes; Hydrogen-Ion Concentration; Male; Mice; Potassium; Potassium Channels; Potassium-Hydrogen Antiporters; Rabbits; Sodium; Sodium-Bicarbonate Symporters; Sodium-Hydrogen Exchangers; Submandibular Gland | 1997 |
Nitric oxide links the apical Na+ transport to the basolateral K+ conductance in the rat cortical collecting duct.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Biological Transport; Calcium; Cyclic GMP; Diuretics; Enzyme Inhibitors; Kidney Tubules, Collecting; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Patch-Clamp Techniques; Penicillamine; Potassium; Potassium Channels; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Sodium; Sodium Channels; Specific Pathogen-Free Organisms | 1997 |
Physiological changes in extracellular sodium directly control human proximal tubule growth and transport.
Topics: Aged; Amiloride; Biological Transport; Cell Division; Cells, Cultured; Culture Media, Serum-Free; DNA; Extracellular Space; Female; Growth Substances; Humans; Insulin-Like Growth Factor I; Kidney Tubules, Proximal; Male; Middle Aged; Platelet-Derived Growth Factor; Protein Biosynthesis; Sodium; Sodium-Hydrogen Exchangers; Transforming Growth Factor beta | 1998 |
Chronic hyperosmolality increases NHE3 activity in OKP cells.
Topics: Amiloride; Animals; Cell Line; Culture Media; Glucose; Hypertonic Solutions; Kidney; Mannitol; Opossums; Osmolar Concentration; Raffinose; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Urea | 1998 |
Regulation of intracellular pH in proximal tubules of avian loopless reptilian-type nephrons.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Ammonium Chloride; Animals; Antiporters; Cell Membrane; Chickens; Female; Fluoresceins; Fluorescent Dyes; Homeostasis; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney Tubules, Distal; Kidney Tubules, Proximal; Male; Nephrons; Rabbits; Snakes | 1997 |
Differential stimulation of the Na+/H+ exchanger determines chloroquine uptake in Plasmodium falciparum.
Topics: Amiloride; Animals; Antimalarials; Chloroquine; Cytoplasm; Drug Resistance; Fluorometry; Humans; Hydrogen-Ion Concentration; Phenotype; Plasmodium falciparum; Sodium-Hydrogen Exchangers | 1998 |
Na+/H+ exchange in vascular smooth muscle cells is controlled by GTP-binding proteins.
Topics: Aluminum Chloride; Aluminum Compounds; Amiloride; Animals; Aorta; Biological Transport; Calcium; Cell Membrane Permeability; Cells, Cultured; Chlorides; Cyclic AMP; Deferoxamine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Hydrogen-Ion Concentration; Isoproterenol; Kinetics; Male; Muscle, Smooth, Vascular; Oligonucleotides, Antisense; Potassium; Rats; Rats, Inbred BN; Sodium; Sodium Fluoride; Thionucleotides | 1998 |
Contribution of cytosolic ionic and energetic milieu change to ischemia- and reperfusion-induced injury in guinea pig heart: fluorometry and nuclear magnetic resonance studies.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Calcium; Cytosol; Enzyme Inhibitors; Female; Fluorometry; Guinea Pigs; Heart; Hydrogen-Ion Concentration; Ion Transport; Magnetic Resonance Spectroscopy; Male; Mitochondria, Heart; Omeprazole; Ouabain; Phosphates; Reperfusion Injury | 1998 |
The mechanism of protection from 5 (N-ethyl-N-isopropyl)amiloride differs from that of ischemic preconditioning in rabbit heart.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Cells, Cultured; Female; Heart; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Myocardium; Protein Kinase C; Rabbits; Sodium-Hydrogen Exchangers | 1997 |
Dependence of mammalian putrescine and spermidine transport on plasma-membrane potential: identification of an amiloride binding site on the putrescine carrier.
Topics: Amiloride; Animals; Binding Sites; Biological Transport; Breast Neoplasms; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Membrane; Female; Humans; Indicators and Reagents; Kinetics; Mammals; Membrane Potentials; Onium Compounds; Organophosphorus Compounds; Potassium; Putrescine; Sodium-Hydrogen Exchangers; Spermidine; Tumor Cells, Cultured; Valinomycin | 1998 |
Angiotensin II activates Na+-independent Cl--HCO3- exchange in ventricular myocardium.
Topics: Alkaloids; Amiloride; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antiporters; Benzophenanthridines; Bicarbonates; Cats; Chloride-Bicarbonate Antiporters; Chlorides; Enzyme Inhibitors; Heart Ventricles; Hydrogen-Ion Concentration; In Vitro Techniques; Losartan; Myocardium; Phenanthridines; Protein Kinase C; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Signal Transduction; Sodium; Sodium-Hydrogen Exchangers | 1998 |
Mechanisms of pHi regulation studied in individual neurons cultured from mouse cerebral cortex.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acids; Alkalies; Amiloride; Ammonium Chloride; Animals; Cells, Cultured; Cerebral Cortex; Chlorides; Fetus; Fluoresceins; Fluorescent Dyes; Hydrogen-Ion Concentration; Intracellular Fluid; Mice; Neurons; Sodium; Sodium Acetate | 1998 |
Both Na+-K+ ATPase and Na +-H+ exchanger are immediately active upon post-ischemic reperfusion in isolated rat hearts.
Topics: Amiloride; Animals; Enzyme Inhibitors; Heart; In Vitro Techniques; Kinetics; Magnetic Resonance Spectroscopy; Male; Myocardial Reperfusion Injury; Myocardium; Ouabain; Perfusion; Rats; Rats, Wistar; Sodium; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase | 1998 |
dGNaC1, a gonad-specific amiloride-sensitive Na+ channel.
Topics: Amiloride; Amino Acid Sequence; Animals; Caenorhabditis elegans; Cations; Drosophila melanogaster; Drosophila Proteins; Embryo, Nonmammalian; Epithelial Sodium Channels; Female; Helix, Snails; Humans; Male; Membrane Potentials; Molecular Sequence Data; Multigene Family; Oocytes; Rabbits; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Sex Characteristics; Sodium; Sodium Channels; Sperm-Ovum Interactions; Testis; Xenopus laevis | 1998 |
Na/H exchange and H-K ATPase increase distal tubule acidification in chronic alkalosis.
Topics: Acid-Base Equilibrium; Acids; Aldosterone; Alkalosis; Amiloride; Animals; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Bicarbonates; Endothelins; Enzyme Inhibitors; Female; H(+)-K(+)-Exchanging ATPase; Imidazoles; Kidney Tubules, Distal; Macrolides; Male; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers | 1998 |
Amiloride analogs inhibit chronic hypoxic pulmonary hypertension.
Topics: Amiloride; Animals; Blood Pressure; Cell Division; Chronic Disease; Hematocrit; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Muscle, Smooth, Vascular; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Vascular Resistance | 1998 |
Heterogeneity of intracellular pH and of mechanisms that regulate intracellular pH in populations of cultured cells.
Topics: Amiloride; Animals; Antiporters; Bicarbonates; Breast Neoplasms; Chloride-Bicarbonate Antiporters; CHO Cells; Cricetinae; Cricetulus; Female; Flow Cytometry; Fluoresceins; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Mammary Neoplasms, Animal; Mice; Potassium; Sarcoma; Sodium-Hydrogen Exchangers; Tumor Cells, Cultured | 1998 |
Evidence for the presence of a Na+-H+ exchanger in the endolymphatic sac epithelium of guinea-pigs.
Topics: Amiloride; Animals; Buffers; Endolymphatic Sac; Epithelium; Female; Fluoresceins; Fluorescent Dyes; Guinea Pigs; Hydrogen-Ion Concentration; Kinetics; Male; Quaternary Ammonium Compounds; Sodium; Sodium-Hydrogen Exchangers | 1998 |
Regulation of intracellular pH in proximal tubules of avian long-looped mammalian-type nephrons.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Ammonia; Ammonium Chloride; Animals; Barium; Chickens; Chlorides; Female; Hydrogen; Hydrogen-Ion Concentration; In Vitro Techniques; Intracellular Membranes; Kidney Tubules, Proximal; Loop of Henle; Nephrons; Permeability; Sodium; Sodium Chloride | 1998 |
Expression of NHE1 and NHE4 in rat pancreatic zymogen granule membranes.
Topics: Amiloride; Animals; Base Sequence; Cell Line; Cytoplasmic Granules; DNA Primers; DNA, Complementary; Enzyme Precursors; Gene Expression; Intracellular Membranes; Male; Microscopy, Immunoelectron; Pancreas; Polymerase Chain Reaction; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers | 1998 |
Effect of vacuolar proton ATPase on pHi, Ca2+, and apoptosis in neonatal cardiomyocytes during metabolic inhibition/recovery.
Topics: Amiloride; Animals; Animals, Newborn; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Apoptosis; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Energy Metabolism; Enzyme Inhibitors; Hydrogen-Ion Concentration; Macrolides; Muscle Fibers, Skeletal; Myocardium; Proton-Translocating ATPases; Rats; Rats, Sprague-Dawley; Sodium-Calcium Exchanger; Sodium-Hydrogen Exchangers; Vacuoles | 1998 |
Altered sodium-hydrogen exchange activity is a mechanism for acid-induced hyperproliferation in Barrett's esophagus.
Topics: Amiloride; Barrett Esophagus; Cell Division; Cell Line; Esophagus; Humans; Hydrogen-Ion Concentration; Kinetics; Mucous Membrane; Organ Culture Techniques; Sodium; Sodium-Hydrogen Exchangers | 1998 |
Non-genomic action of the mineralocorticoid aldosterone on cytosolic sodium in cultured kidney cells.
Topics: Aldosterone; Amiloride; Animals; Cell Line; Cell Membrane; Cytosol; Dogs; Epithelial Cells; Hydrogen-Ion Concentration; Kidney; Kinetics; Models, Biological; Ouabain; Sodium; Zinc | 1998 |
Can we use erythrocytes for the study of the activity of the ubiquitous Na+/H+ exchanger (NHE-1) in essential hypertension?
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Amiloride; Animals; Anti-Arrhythmia Agents; Antiporters; Cell Size; Cytosol; Diuretics; Erythrocyte Aging; Erythrocytes; Extracellular Space; Hydrogen-Ion Concentration; Hypertension; Ion Transport; Male; Rabbits; Rats; Rats, Wistar; Sodium; Sodium-Hydrogen Exchangers; Species Specificity | 1998 |
Intracellular pH regulation in bovine aortic endothelial cells: evidence of both Na+/H+ exchange and Na+-dependent Cl-/HCO3- exchange.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Ammonium Chloride; Animals; Antiporters; Aorta; Bicarbonates; Carbon Dioxide; Cattle; Cells, Cultured; Chloride-Bicarbonate Antiporters; Chlorides; Endothelium, Vascular; Hydrogen-Ion Concentration; Sodium; Sodium-Hydrogen Exchangers | 1998 |
Mechanisms of pH preservation during global ischemia in preconditioned rat heart: roles for PKC and NHE.
Topics: Acidosis; Adenosine Triphosphate; Adrenergic alpha-Agonists; Amiloride; Animals; Guanidines; Hydrogen-Ion Concentration; Ischemic Preconditioning, Myocardial; Kinetics; Male; Myocardial Ischemia; Phenylephrine; Phosphates; Protein Kinase C; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium-Hydrogen Exchangers; Sulfones | 1998 |
Influence of extracellular pH on intracellular pH in arterioles and skeletal muscle of spontaneously hypertensive and Wistar-Kyoto rats.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Arterioles; Blood Pressure; Extracellular Space; Hydrogen-Ion Concentration; Kidney; Male; Mesenteric Arteries; Muscle, Skeletal; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium | 1998 |
Role of intracellular Ca2+ and pH in positive inotropic response of cardiomyocytes to diacylglycerol.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Calcium; Calibration; Cells, Cultured; Diastole; Diglycerides; Electric Stimulation; Fluorescent Dyes; Heart Ventricles; Hydrogen-Ion Concentration; Male; Myocardial Contraction; Myocardium; Rats; Sarcoplasmic Reticulum; Spectrometry, Fluorescence; Systole; Time Factors | 1998 |
Inhibition of Na+/H+ exchange stimulates CCK secretion in STC-1 cells.
Topics: Amiloride; Animals; Antigens, Polyomavirus Transforming; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell Membrane; Cell Membrane Permeability; Cholecystokinin; Diltiazem; Hydrogen-Ion Concentration; Insulin; Intestinal Neoplasms; Mice; Mice, Transgenic; Polyomavirus; Potassium; Potassium Channels; Promoter Regions, Genetic; Rats; Simian virus 40; Sodium; Sodium-Hydrogen Exchangers | 1998 |
Characterization of the Na+/H+ exchanger in the luminal membrane of the distal nephron.
Topics: Amiloride; Animals; Biological Transport; Bucladesine; Cell Membrane; Cimetidine; Clonidine; Cyclic AMP-Dependent Protein Kinases; In Vitro Techniques; Kidney Tubules, Distal; Kidney Tubules, Proximal; Kinetics; Nephrons; Rabbits; Rats; Sodium; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 1998 |
Equal reduction in infarct size by ethylisopropyl-amiloride pretreatment and ischemic preconditioning in the in situ rabbit heart.
Topics: Amiloride; Animals; Female; Ion Transport; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Rabbits; Rats; Sodium; Sodium-Calcium Exchanger; Sodium-Hydrogen Exchangers | 1998 |
Stretch-induced alkalinization of feline papillary muscle: an autocrine-paracrine system.
Topics: Alkalies; Alkaloids; Amiloride; Angiotensin II; Animals; Anti-Arrhythmia Agents; Autocrine Communication; Benzophenanthridines; Cats; Endothelin Receptor Antagonists; Endothelins; Enzyme Inhibitors; Heart; Hydrogen-Ion Concentration; Losartan; Muscle Contraction; Muscle Fibers, Skeletal; Oligopeptides; Papillary Muscles; Paracrine Communication; Peptides, Cyclic; Phenanthridines; Protein Kinase C; Sodium-Hydrogen Exchangers | 1998 |
Contribution of Na+-H+ exchange to sodium reabsorption in the loop of henle: a microperfusion study in rats.
Topics: Amiloride; Anesthesia; Animals; Anti-Arrhythmia Agents; Bicarbonates; Bumetanide; Diuretics; Glomerular Filtration Rate; In Vitro Techniques; Kidney Tubules, Proximal; Loop of Henle; Male; Perfusion; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Hydrogen Exchangers | 1998 |
5-(N-Ethyl-N-isopropyl)-amiloride inhibits amino acid release from the ischemic rat cerebral cortex: role of Na+-H+ exchange.
Topics: Amiloride; Amino Acids; Animals; Brain Ischemia; Male; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers | 1998 |
P2 receptor-mediated signal transduction in Ehrlich ascites tumor cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Amiloride; Animals; Calcium Signaling; Carcinoma, Ehrlich Tumor; Cell Size; Enzyme Inhibitors; Estrenes; Hydrogen-Ion Concentration; Mice; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyrrolidinones; Receptors, Purinergic P2; Signal Transduction; Sodium-Hydrogen Exchangers; Suramin; Thapsigargin; Type C Phospholipases; Uridine Triphosphate | 1998 |
Regulation of intracellular pH in hamster preimplantation embryos by the sodium hydrogen (Na+/H+) antiporter.
Topics: Acid-Base Equilibrium; Acidosis; Amiloride; Animals; Antiporters; Chloride-Bicarbonate Antiporters; Cleavage Stage, Ovum; Cricetinae; Culture Media; Culture Techniques; Embryo, Mammalian; Embryonic Development; Female; Hydrogen-Ion Concentration; Mesocricetus; Pregnancy; Proton-Translocating ATPases; Sodium; Sodium-Hydrogen Exchangers | 1998 |
Regulation of macula densa Na:H exchange by angiotensin II.
Topics: Acids; Alkalies; Amiloride; Angiotensin II; Animals; Dose-Response Relationship, Drug; Fluoresceins; Fluorescent Dyes; Hydrogen-Ion Concentration; In Vitro Techniques; Intracellular Membranes; Loop of Henle; Microscopy, Fluorescence; Osmolar Concentration; Rabbits; Sodium Chloride; Sodium-Hydrogen Exchangers | 1998 |
Altered inotropic response of endothelin-1 in cardiomyocytes from rats with isoproterenol-induced cardiomyopathy.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Anti-Arrhythmia Agents; Calcium; Cardiotonic Agents; Cell Size; Cells, Cultured; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Heart Failure; Hemodynamics; Isoproterenol; Male; Myocardial Contraction; Myocardium; Peptides, Cyclic; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptors, Endothelin; Sodium-Hydrogen Exchangers; Staurosporine | 1998 |
Potassium secretion in rat distal colon during dietary potassium loading: role of pH regulated apical potassium channels.
Topics: Amiloride; Animals; Cell Culture Techniques; Colon; Hydrogen-Ion Concentration; Male; Patch-Clamp Techniques; Potassium; Potassium Channels; Potassium, Dietary; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers | 1999 |
Short-term effects of thyroid hormones on the Na/H antiport in L-6 myoblasts: high molecular specificity for 3,3',5-triiodo-L-thyronine.
Topics: Amiloride; Animals; Antimetabolites; Cell Line; Hydrogen-Ion Concentration; Intracellular Membranes; Muscle, Skeletal; Osmolar Concentration; Propylthiouracil; Rats; Sodium-Hydrogen Exchangers; Thyroxine; Time Factors; Triiodothyronine | 1999 |
Effect of PACAP-27 on adenylate cyclase in ductal and acinar cells of rat submandibular gland.
Topics: Adenylyl Cyclases; Amiloride; Animals; Calcium; Carrier Proteins; Epinephrine; In Vitro Techniques; Isoproterenol; Kinetics; Male; Neuropeptides; Ouabain; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Wistar; Sodium-Potassium-Chloride Symporters; Submandibular Gland; Thapsigargin | 1998 |
Molecular cloning and functional expression of a rat Na+/H+ exchanger (NHE5) highly expressed in brain.
Topics: Amiloride; Amino Acid Sequence; Animals; Base Sequence; Brain Chemistry; Cloning, Molecular; Dentate Gyrus; Humans; Membrane Proteins; Molecular Sequence Data; Polymerase Chain Reaction; Rats; Sequence Alignment; Sodium-Hydrogen Exchangers | 1999 |
Expression of multiple Na+/H+ exchanger isoforms in rat parotid acinar and ductal cells.
Topics: Amiloride; Animals; Blotting, Western; Culture Techniques; Immunohistochemistry; Isomerism; Male; Parotid Gland; Rats; Rats, Wistar; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sodium-Hydrogen Exchangers; Tissue Distribution | 1999 |
Mechanisms of basolateral Na+ transport in rabbit esophageal epithelial cells.
Topics: Amiloride; Ammonia; Animals; Bicarbonates; Biological Transport; Bumetanide; Chlorides; Epithelial Cells; Esophagus; Homeostasis; Hydrogen-Ion Concentration; In Vitro Techniques; Intracellular Membranes; Isotonic Solutions; Rabbits; Sodium | 1999 |
Shrinkage-induced activation of Na+/H+ exchange in rat renal mesangial cells.
Topics: Amiloride; Animals; Cells, Cultured; Chlorides; Fluoresceins; Fluorescent Dyes; Glomerular Mesangium; Homeostasis; Hydrogen-Ion Concentration; Osmolar Concentration; Potassium; Rats; Sodium; Sodium-Hydrogen Exchangers | 1999 |
Effects of arginine vasopressin on cell volume regulation in brain astrocyte in culture.
Topics: Amiloride; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Astrocytes; Brain; Cells, Cultured; Culture Media; Deamino Arginine Vasopressin; Female; Hypotonic Solutions; Rats; Receptors, Vasopressin; Time Factors | 1999 |
Influence of Bretschneider's cardioplegia on norepinephrine release from isolated perfused guinea-pig hearts.
Topics: Adrenergic Uptake Inhibitors; Amiloride; Animals; Desipramine; Dose-Response Relationship, Drug; Fever; Glucose; Guinea Pigs; Heart Arrest, Induced; Hypothermia; Ion Exchange; Mannitol; Myocardial Ischemia; Myocardium; Norepinephrine; Perfusion; Potassium Chloride; Procaine; Reperfusion; Temperature; Time Factors | 1999 |
Nerve growth factor inhibits HCO3- absorption in renal thick ascending limb through inhibition of basolateral membrane Na+/H+ exchange.
Topics: Absorption; Amiloride; Animals; Basement Membrane; Bicarbonates; Epithelium; Kidney Medulla; Loop of Henle; Male; Nerve Growth Factors; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers | 1999 |
Na+/H+ antiporter activity in hamster embryos is activated during fertilization.
Topics: Amiloride; Animals; Antiporters; Calcium; Chelating Agents; Chloride-Bicarbonate Antiporters; Cricetinae; Egtazic Acid; Embryo, Mammalian; Fertilization; Hydrogen-Ion Concentration; Mesocricetus; Oocytes; Protein Kinase C; Protein Synthesis Inhibitors; Sodium; Sodium-Hydrogen Exchangers; Sphingosine; Tetradecanoylphorbol Acetate | 1999 |
Calcium-calmodulin modulation of the activity of Na+/H+ exchanger in human platelets.
Topics: Amiloride; Blood Platelets; Calcium; Calmodulin; Dose-Response Relationship, Drug; Humans; Hydrogen-Ion Concentration; Sodium-Hydrogen Exchangers; Thrombin; Time Factors; Trifluoperazine | 1998 |
Ethyl isopropylamiloride downregulates Na,K-ATPase gene expression which confers cytotoxicity in primary proximal tubule cell cultures.
Topics: Acidosis; Amiloride; Animals; Anti-Arrhythmia Agents; Blotting, Northern; Cell Survival; Cells, Cultured; Enzyme Activation; Gene Expression Regulation, Enzymologic; Hydrogen-Ion Concentration; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Rabbits; RNA, Messenger; Sodium-Potassium-Exchanging ATPase | 1998 |
Targeted disruption of the murine Nhe1 locus induces ataxia, growth retardation, and seizures.
Topics: Amiloride; Animals; Ataxia; Base Sequence; Body Weight; Chimera; Crosses, Genetic; Death; Embryonic and Fetal Development; Exons; Female; Gastric Mucosa; Growth Disorders; Homozygote; Lacrimal Apparatus; Male; Mice; Mice, Knockout; Seizures; Sodium-Hydrogen Exchangers; Transcription, Genetic | 1999 |
Cellular uptake of chloroquine is dependent on binding to ferriprotoporphyrin IX and is independent of NHE activity in Plasmodium falciparum.
Topics: Amiloride; Animals; Antimalarials; Bicarbonates; Biological Transport; Chloroquine; Erythrocyte Membrane; Erythrocytes; Hemin; Hemoglobins; Humans; Hydrogen-Ion Concentration; Kinetics; Leupeptins; Plasmodium falciparum; Sodium-Hydrogen Exchangers; Verapamil | 1999 |
Inhibition of Na+-H+ exchanger protects diabetic and non-diabetic hearts from ischemic injury: insight into altered susceptibility of diabetic hearts to ischemic injury.
Topics: Acidosis; Adenosine Triphosphate; Amiloride; Animals; Calcium; Diabetes Mellitus, Type 1; Hydrogen-Ion Concentration; In Vitro Techniques; Intracellular Fluid; Magnetic Resonance Spectroscopy; Myocardial Reperfusion Injury; Phosphocreatine; Quaternary Ammonium Compounds; Rats; Rats, Inbred BB; Sodium; Sodium-Hydrogen Exchangers | 1999 |
Increases in [Ca2+]i and changes in intracellular pH during chemical anoxia in mouse neocortical neurons in primary culture.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amiloride; Animals; Calcium; Cell Hypoxia; Cells, Cultured; Excitatory Amino Acid Antagonists; Extracellular Space; Female; Fluoresceins; Fura-2; Glucose; Hydrogen-Ion Concentration; Mice; Mice, Inbred Strains; Neocortex; Neurons; Sodium Azide; Sodium-Hydrogen Exchangers | 1999 |
Neonatal rabbit proximal tubule basolateral membrane Na+/H+ antiporter and Cl-/base exchange.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetazolamide; Aging; Amiloride; Animals; Animals, Newborn; Antiporters; Bicarbonates; Chloride-Bicarbonate Antiporters; Cyanides; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney Tubules, Proximal; Rabbits; Sodium-Hydrogen Exchangers | 1999 |
Rapid effects of aldosterone on sodium-hydrogen exchange in isolated colonic crypts.
Topics: Aldosterone; Amiloride; Animals; Arachidonic Acid; Bicarbonates; Colon; Diuretics; Extracellular Space; Fluoresceins; Fluorescent Dyes; Hydrogen-Ion Concentration; Ion Exchange; Ion Transport; Leukotriene Antagonists; Male; Mineralocorticoid Receptor Antagonists; Phospholipases; Prostaglandin Antagonists; Protein Biosynthesis; Protein Kinase Inhibitors; Protein Kinases; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Hydrogen Exchangers; Spironolactone; Transcription, Genetic | 1999 |
Basolateral regulation of pHi in proximal tubules of avian loopless and long-looped nephrons in bicarbonate.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Ammonia; Ammonium Chloride; Animals; Barium; Bicarbonates; Chickens; Chlorides; Female; Hydrogen-Ion Concentration; Kidney Tubules, Proximal; Potassium; Sodium | 1999 |
Essential requirement of cytosolic phospholipase A(2) for activation of the H(+) channel in phagocyte-like cells.
Topics: Amiloride; Anti-Arrhythmia Agents; Calcitriol; Cell Differentiation; Cell Line; Cytosol; Dimethyl Sulfoxide; Humans; Hydrogen-Ion Concentration; Neutrophils; Phagocytes; Phospholipases A; Proton Pumps; Recombinant Proteins; Sodium-Hydrogen Exchangers; Superoxides; Tetradecanoylphorbol Acetate; Transfection; Zinc | 1999 |
Mechanism of proximal tubule bicarbonate absorption in NHE3 null mice.
Topics: Absorption; Amiloride; Animals; Anti-Bacterial Agents; Bicarbonates; Enzyme Inhibitors; H(+)-K(+)-Exchanging ATPase; Imidazoles; Kidney Tubules, Proximal; Macrolides; Mice; Mice, Knockout; Reference Values; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers | 1999 |
5-(N-Ethyl-N-isopropyl)-amiloride, an Na(+)-H(+) exchange inhibitor, protects gerbil hippocampal neurons from ischemic injury.
Topics: Amiloride; Animals; Brain Ischemia; Gerbillinae; Hippocampus; Male; Neurons; Neuroprotective Agents; Reperfusion Injury; Sodium-Hydrogen Exchangers | 1999 |
Intracellular pH regulation of CA1 neurons in Na(+)/H(+) isoform 1 mutant mice.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Ammonium Chloride; Animals; Ataxia; Benzopyrans; Bicarbonates; Carbon Dioxide; Coloring Agents; Guanidines; Hydrogen-Ion Concentration; Intracellular Fluid; Ion Transport; Mice; Mice, Knockout; Mice, Neurologic Mutants; Microscopy, Confocal; Naphthols; Neurons; Protein Isoforms; Protons; Rhodamines; Sodium; Sodium-Hydrogen Exchangers; Sulfones | 1999 |
Regulation of acidification and apoptosis by SHP-1 and Bcl-2.
Topics: Amiloride; Apoptosis; bcl-2-Associated X Protein; Cyclin D1; Fas Ligand Protein; Humans; Hydrogen-Ion Concentration; Intracellular Signaling Peptides and Proteins; Membrane Glycoproteins; Membrane Proteins; Mutation; Octreotide; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Receptors, Somatostatin; SH2 Domain-Containing Protein Tyrosine Phosphatases; Signal Transduction; Somatostatin; src Homology Domains; Time Factors; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1999 |
Mechanisms underlying the increase in force and Ca(2+) transient that follow stretch of cardiac muscle: a possible explanation of the Anrep effect.
Topics: Amiloride; Angiotensin Receptor Antagonists; Animals; Bicarbonates; Calcium; Endothelin Receptor Antagonists; Hydrogen-Ion Concentration; Intracellular Membranes; Models, Cardiovascular; Myocardial Contraction; Papillary Muscles; Physical Stimulation; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Endothelin A; Sodium; Sodium-Hydrogen Exchangers | 1999 |
LLC-PK(1) cells stably expressing the human norepinephrine transporter: A functional model of carrier-mediated norepinephrine release in protracted myocardial ischemia.
Topics: 1-Methyl-4-phenylpyridinium; Amiloride; Animals; Biological Transport, Active; Desipramine; Drug Interactions; Gramicidin; Humans; Imidazoline Receptors; LLC-PK1 Cells; Mazindol; Models, Biological; Myocardial Ischemia; Nigericin; Norepinephrine; Receptors, Drug; Sodium; Swine; Time Factors | 1999 |
Inhibition of Na+-H+ exchange impairs receptor-mediated albumin endocytosis in renal proximal tubule-derived epithelial cells from opossum.
Topics: Amiloride; Animals; Binding Sites; Cell Membrane; Cytosol; Endocytosis; Endosomes; Epithelial Cells; Guanidines; Hydrogen-Ion Concentration; Kidney Tubules, Proximal; Lysosomes; Opossums; Propionates; Receptors, Cell Surface; Serum Albumin; Sodium; Sodium-Hydrogen Exchangers; Sulfones | 1999 |
A role for Na+/H+ exchange in pH regulation in Helix neurones.
Topics: Acids; Amiloride; Animals; Antiporters; Chloride-Bicarbonate Antiporters; Helix, Snails; Hydrogen; Hydrogen-Ion Concentration; Isotonic Solutions; Neurons; Ringer's Solution; Sodium; Sodium-Hydrogen Exchangers | 1999 |
The paracellular permeability of opossum kidney cells, a proximal tubule cell line.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Calcium; Carcinogens; Cell Culture Techniques; Cell Membrane Permeability; Clone Cells; Kidney Tubules, Proximal; LLC-PK1 Cells; Mannitol; Nephrons; Opossums; Sodium; Swine; Tetradecanoylphorbol Acetate; Tight Junctions; Tritium; Urothelium | 1999 |
Influence of a Na+-H+ exchange inhibitor ethylisopropylamiloride, a Na+-Ca2+ exchange inhibitor KB-R7943 and their combination on the increases in contractility and Ca2+ transient induced by angiotensin II in isolated adult rabbit ventricular myocytes.
Topics: Amiloride; Angiotensin II; Animals; Calcium; Calcium Signaling; Drug Interactions; Heart; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Rabbits; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sodium-Calcium Exchanger; Sodium-Hydrogen Exchangers; Thiourea | 1999 |
NBC3 expression in rabbit collecting duct: colocalization with vacuolar H+-ATPase.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Bicarbonates; Carrier Proteins; Immunohistochemistry; In Vitro Techniques; Kidney; Kidney Medulla; Kidney Tubules, Collecting; Kinetics; Male; Membrane Proteins; Perfusion; Proton Pumps; Proton-Translocating ATPases; Rabbits; Sodium-Bicarbonate Symporters; Vacuolar Proton-Translocating ATPases | 1999 |
Cardioprotection of SM-15681, an Na+/H+ exchange inhibitor in ischemic and hypoxic isolated perfused rat hearts.
Topics: Amides; Amiloride; Animals; Anti-Arrhythmia Agents; Hydrogen; Indoles; Ion Transport; Myocardial Ischemia; Myocardial Reperfusion Injury; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sodium; Sodium-Hydrogen Exchangers | 1999 |
Increased Na(+)/H(+) exchanger isoform 1 activity in spontaneously hypertensive rats: lack of mutations within the coding region of NHE1.
Topics: Amiloride; Animals; Aorta; Cells, Cultured; Crosses, Genetic; DNA Mutational Analysis; DNA, Complementary; Female; Genetic Variation; Hypertension; Ion Transport; Male; Muscle Proteins; Muscle, Smooth, Vascular; Ouabain; Polymorphism, Single-Stranded Conformational; Protein Isoforms; Protons; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium; Sodium-Hydrogen Exchangers | 2000 |
NHE1, NHE2, and NHE3 contribute to regulation of intracellular pH in murine duodenal epithelial cells.
Topics: Amiloride; Ammonia; Animals; Blotting, Western; Duodenum; Epithelial Cells; Extracellular Space; Homeostasis; Hydrogen-Ion Concentration; Kinetics; Mice; Mice, Inbred C57BL; Quaternary Ammonium Compounds; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium; Sodium-Hydrogen Exchangers; Spectrometry, Fluorescence | 2000 |
Kinetic and pharmacological properties of human brain Na(+)/H(+) exchanger isoform 5 stably expressed in Chinese hamster ovary cells.
Topics: Adenosine Triphosphate; Amiloride; Animals; Brain; CHO Cells; Cimetidine; Cricetinae; Guanidines; Harmaline; Humans; Hydrogen-Ion Concentration; Kinetics; Lithium; Membrane Proteins; Potassium; Protein Isoforms; Sodium Radioisotopes; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sulfones; Transfection | 2000 |
Allosteric interactions between the antagonist prazosin and amiloride analogs at the human alpha(1A)-adrenergic receptor.
Topics: Adrenergic alpha-Antagonists; Allosteric Regulation; Amiloride; Animals; Binding, Competitive; CHO Cells; Cricetinae; Diuretics; Humans; Prazosin; Radioligand Assay; Receptors, Adrenergic, alpha-1; Tritium | 2000 |
Intracellular pH in mammalian stages of Trypanosoma cruzi is K+-dependent and regulated by H+-ATPases.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Amiloride; Animals; Bicarbonates; Buffers; Chlorides; Enzyme Inhibitors; Gene Expression Regulation; H(+)-K(+)-Exchanging ATPase; Homeostasis; Hydrogen-Ion Concentration; Potassium; Proton Pump Inhibitors; Protons; Sodium; Trypanosoma cruzi | 2000 |
Estradiol-17beta-BSA stimulates Ca(2+) uptake through nongenomic pathways in primary rabbit kidney proximal tubule cells: involvement of cAMP and PKC.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Amiloride; Animals; Anti-Arrhythmia Agents; Biological Transport; Calcium; Cells, Cultured; Cyclic AMP; Cycloheximide; Dactinomycin; Enzyme Inhibitors; Estradiol; Estrenes; Estrogens, Conjugated (USP); Gallopamil; Kidney Tubules, Proximal; Kinetics; Male; Parathyroid Hormone; Phosphodiesterase Inhibitors; Protein Kinase C; Pyrrolidinones; Rabbits; Serum Albumin, Bovine; Tamoxifen; Tetradecanoylphorbol Acetate | 2000 |
[The role of sodium-proton exchange in the regulation of the electric and contractile activity of smooth muscles].
Topics: Action Potentials; Amiloride; Animals; Calcium Chloride; Cell Membrane; Gramicidin; Hydrogen-Ion Concentration; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Potassium; Rabbits; Sodium-Hydrogen Exchangers; Taenia; Ureter | 2000 |
Regulation of NHE3 activity by G protein subunits in renal brush-border membranes.
Topics: Adrenergic alpha-Agonists; Amiloride; Animals; Benzazepines; Brimonidine Tartrate; Cell Line, Transformed; Dopamine Agonists; Dose-Response Relationship, Drug; Enzyme Activation; Fenoldopam; GTP-Binding Protein alpha Subunits; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein beta Subunits; GTP-Binding Protein gamma Subunits; GTP-Binding Proteins; Heterotrimeric GTP-Binding Proteins; Kidney Tubules, Proximal; Male; Microvilli; Neuroprotective Agents; Pertussis Toxin; Quinoxalines; Rats; Rats, Inbred WKY; Receptors, Dopamine D1; Second Messenger Systems; Sodium Radioisotopes; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Virulence Factors, Bordetella | 2000 |
Novel amiloride-sensitive sodium-dependent proton secretion in the mouse proximal convoluted tubule.
Topics: Amiloride; Animals; Guanidines; Kidney Tubules, Proximal; Mice; Mice, Inbred C57BL; Mice, Knockout; Protons; Sodium; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sulfones | 2000 |
Polarization of Na(+)/H(+) and Cl(-)/HCO (3)(-) exchangers in migrating renal epithelial cells.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Antiporters; Biological Transport; Cell Line; Cell Movement; Cell Polarity; Cell Size; Chloride-Bicarbonate Antiporters; Dogs; Epithelial Cells; Guanidines; Hydrogen-Ion Concentration; Intercellular Signaling Peptides and Proteins; Kidney; Osmotic Pressure; Peptides; Salts; Sodium-Hydrogen Exchangers; Spider Venoms; Sulfones; Water | 2000 |
Extracellular Cl(-) modulates shrinkage-induced activation of Na(+)/H(+) exchanger in rat mesangial cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Cell Size; Cells, Cultured; Chlorides; Colchicine; Fluoresceins; Glomerular Mesangium; Hydrogen-Ion Concentration; Hypertonic Solutions; Male; Nitrobenzoates; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers | 2000 |
Slowly inactivating component of sodium current in ventricular myocytes is decreased by diabetes and partially inhibited by known Na(+)-H(+)Exchange blockers.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Cells, Cultured; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Guanidines; Heart Ventricles; Lysophosphatidylcholines; Male; Myocardium; Patch-Clamp Techniques; Rats; Rats, Wistar; Sodium Channels; Sodium-Hydrogen Exchangers; Streptozocin; Sulfones; Tetrodotoxin; Veratrine | 2000 |
Intracellular pH in isolated rat renal papillary thin limbs of Henle's loop.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acid-Base Equilibrium; Amiloride; Ammonia; Ammonium Chloride; Animals; Bicarbonates; Carrier Proteins; Cell Membrane Permeability; Chlorides; Fluoresceins; Fluorescent Dyes; In Vitro Techniques; Intracellular Fluid; Loop of Henle; Male; Perfusion; Potassium; Rats; Rats, Wistar; Sodium; Sodium-Bicarbonate Symporters; Sodium-Hydrogen Exchangers | 2000 |
Cloning and expression of a FMRFamide-gated Na(+) channel from Helisoma trivolvis and comparison with the native neuronal channel.
Topics: Amiloride; Animals; Cells, Cultured; Cloning, Molecular; FMRFamide; Gene Expression; Ion Channel Gating; Molecular Sequence Data; Neurons; Neuroprotective Agents; Oocytes; Patch-Clamp Techniques; Sequence Homology, Amino Acid; Snails; Sodium Channels; Transfection; Xenopus | 2000 |
Inhibition of both Na/H and bicarbonate-dependent exchange is required to prevent recovery of intracellular pH in single cardiomyocytes exposed to metabolic stress.
Topics: 2,4-Dinitrophenol; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Benzopyrans; Bicarbonates; Biological Transport; Cell Hypoxia; Fluorescent Dyes; Guinea Pigs; Hydrogen; Hydrogen-Ion Concentration; Myocardium; Naphthols; Oxygen; Rhodamines; Sodium; Sodium-Hydrogen Exchangers; Stress, Physiological; Uncoupling Agents | 1999 |
Role of Na+/H+ exchange and HCO3- transport in pHi recovery from intracellular acid load in cultured epithelial cells of sheep rumen.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acidosis; Amiloride; Animals; Anti-Arrhythmia Agents; Bicarbonates; Biological Transport; Butyrates; Carbon Dioxide; Cell Culture Techniques; Cells, Cultured; Epithelial Cells; Fluoresceins; Guanidines; Hydrogen-Ion Concentration; Rumen; Sheep; Sodium-Hydrogen Exchangers; Sulfones | 2000 |
Comparison of the protective effects of ischemic preconditioning and the Na+/H+ exchanger blockade.
Topics: Adenosine Triphosphate; Amiloride; Animals; Anti-Arrhythmia Agents; Blood Pressure; Enzyme Inhibitors; Guanidines; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Myocardial Contraction; Myocardium; Protein Kinase C; Rats; Sodium-Hydrogen Exchangers; Sulfones; Ventricular Function, Left | 2000 |
Dopamine inhibits na,h-exchanger via D1-like receptor-mediated stimulation of protein kinase a in renal proximal tubules.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amiloride; Animals; Bucladesine; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dopamine; Dopamine Agonists; Enzyme Inhibitors; Kidney Tubules, Proximal; Male; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Sodium-Hydrogen Exchangers | 2000 |
Differential regulation of norepinephrine- and prostaglandin F2alpha-induced contraction by extracellular Na+ in rat aorta.
Topics: Amiloride; Animals; Aorta, Thoracic; Calcium; Dinoprost; Dose-Response Relationship, Drug; HEPES; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Sodium; Vasoconstriction | 2000 |
pH(i) responses to osmotic cell shrinkage in the presence of open-system buffers.
Topics: Amiloride; Animals; Anti-Bacterial Agents; Buffers; Cell Size; Cells, Cultured; Hydrogen-Ion Concentration; Hypertonic Solutions; Kinetics; Macrolides; Macrophages, Alveolar; Mannitol; Models, Biological; Propionates; Rabbits; Saline Solution, Hypertonic; Sucrose | 2000 |
Mechanisms of endothelial cell swelling from lactacidosis studied in vitro.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acidosis, Lactic; Amiloride; Animals; Bicarbonates; Biological Transport; Buffers; Cattle; Cells, Cultured; Culture Media; Endothelium, Vascular; HEPES; Hydrogen-Ion Concentration; Signal Processing, Computer-Assisted; Sodium-Hydrogen Exchangers | 2000 |
Regulation of the formation of tumor cell pseudopodia by the Na(+)/H(+) exchanger NHE1.
Topics: Actin Cytoskeleton; Actins; Amiloride; Animals; Cell Adhesion; Cell Line; Cell Line, Transformed; Cell Movement; Cell Size; Cell Transformation, Neoplastic; Dogs; Fluorescent Antibody Technique, Indirect; Hydrogen-Ion Concentration; Microscopy, Video; Nocodazole; Phenotype; Pseudopodia; Sodium-Hydrogen Exchangers; Stress Fibers | 2000 |
Inhibition of NHE protects reoxygenated cardiomyocytes independently of anoxic Ca(2+) overload and acidosis.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Calcium; Carrier Proteins; Cell Hypoxia; Cells, Cultured; Cytosol; Fluorescent Dyes; Guanidines; Hydrogen-Ion Concentration; Magnesium; Male; Myocardial Contraction; Myocardial Ischemia; Myocardium; Oxygen; Rats; Rats, Wistar; Sodium; Sodium-Bicarbonate Symporters; Sodium-Hydrogen Exchangers; Sulfones | 2000 |
Na(+)/H(+) exchange in mosquito Malpighian tubules.
Topics: Aedes; Amiloride; Ammonium Chloride; Animals; Cell Membrane; Clonidine; Harmaline; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Malpighian Tubules; Sodium; Sodium-Hydrogen Exchangers | 2000 |
Evidence for a direct correlation between c-Jun NH2 terminal kinase 1 activation, cyclin D2 expression, and G(1)/S phase transition in the murine hybridoma 7TD1 cells.
Topics: Amiloride; Animals; Cell Cycle; Cyclin D2; Cyclins; Enzyme Activation; Enzyme Inhibitors; Ethylamines; G1 Phase; Humans; Hybridomas; Imidazoles; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Pyridines; Recombinant Proteins; S Phase | 2000 |
Inhibition of Na(+)/H(+) exchange by 5-(N-ethyl-N-isopropyl)-amiloride reduces free fatty acid efflux from the ischemic reperfused rat cerebral cortex.
Topics: Acidosis; Amiloride; Animals; Brain Ischemia; Cardiovascular Physiological Phenomena; Cerebral Cortex; Electroencephalography; Fatty Acids, Nonesterified; Glucose; Lactic Acid; Male; Neuroprotective Agents; Phospholipases; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sodium-Hydrogen Exchangers | 2000 |
The shrinkage-activated Na(+) conductance of rat hepatocytes and its possible correlation to rENaC.
Topics: Amiloride; Animals; Cell Size; Cells, Cultured; DNA, Complementary; Epithelial Sodium Channels; Hepatocytes; Humans; Immediate-Early Proteins; Immunoblotting; Inhibitory Concentration 50; Ion Channel Gating; Microinjections; Nuclear Proteins; Oocytes; Osmolar Concentration; Osmotic Pressure; Patch-Clamp Techniques; Protein Serine-Threonine Kinases; Protein Subunits; Rats; RNA, Messenger; Sodium; Sodium Channels; Xenopus | 2000 |
Effect of SMP-300, a new Na+/H+ exchange inhibitor, on myocardial ischemia and experimental angina models in rats.
Topics: Amiloride; Angina Pectoris; Animals; Azocines; Blood Pressure; Disease Models, Animal; Electrocardiography; Heart; Heart Rate; Isoproterenol; Male; Myocardial Ischemia; Myocardium; Neuroprotective Agents; Pyrroles; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Vasopressins | 2000 |
HCO3- salvage mechanisms in the submandibular gland acinar and duct cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Alternative Splicing; Amiloride; Animals; Bicarbonates; Biological Transport; Carrier Proteins; Cell Membrane; Dose-Response Relationship, Drug; Epithelial Cells; Hydrogen; Hydrogen-Ion Concentration; Immunohistochemistry; Inhibitory Concentration 50; Ion Transport; Male; Mice; Mice, Knockout; Microscopy, Fluorescence; Neuroprotective Agents; Perfusion; Potassium; Protons; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Submandibular Gland | 2001 |
Inhibition of the NA(+)/H(+) exchanger reduces rat hepatic stellate cell activity and liver fibrosis: an in vitro and in vivo study.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Antineoplastic Agents; Ascorbic Acid; Carcinogens; Cell Division; Collagen; Diuretics; Ferric Compounds; Ferrous Compounds; Gene Expression; Hydrogen-Ion Concentration; In Situ Nick-End Labeling; Liver; Liver Cirrhosis; Male; Nitrilotriacetic Acid; Procollagen; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Messenger; Sodium-Hydrogen Exchangers; Thymidine Phosphorylase; Transforming Growth Factor beta | 2001 |
Characterization of apical membrane Cl-dependent Na/H exchange in crypt cells of rat distal colon.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Cell Membrane; Chloride Channels; Chlorides; Colon; Diet, Sodium-Restricted; Dose-Response Relationship, Drug; Guanidines; Intestinal Mucosa; Ion Transport; Nitrobenzoates; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Sulfones | 2001 |
Na+-overload during ischemia and reperfusion in rat hearts: comparison of the Na+/H+-exchange blockers EIPA, HOE642 and EMD96785.
Topics: Amiloride; Animals; Guanidines; In Vitro Techniques; Magnetic Resonance Spectroscopy; Myocardial Ischemia; Myocardial Reperfusion Injury; Rats; Sodium; Sodium-Hydrogen Exchangers; Sulfones | 2000 |
Effect of ethylisopropyl amiloride, a Na+ - H+ exchange inhibitor, on cardioprotective effect of ischaemic and angiotensin preconditioning.
Topics: Amiloride; Angiotensin II; Animals; Cardiovascular Agents; Creatine Kinase; Female; Hemodynamics; Ischemic Preconditioning, Myocardial; L-Lactate Dehydrogenase; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Rats; Sodium-Hydrogen Exchangers | 2000 |
Protective effect of SM-20550, a selective Na+ - H+ exchange inhibitor, on ischemia-reperfusion-injured hearts.
Topics: Adenosine Triphosphate; Amidines; Amiloride; Animals; Calcium; Female; Guinea Pigs; Hydrogen-Ion Concentration; Indoles; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Protective Agents; Sodium; Sodium-Hydrogen Exchangers; Ventricular Function, Left | 2001 |
Roles of ATP and cytoskeleton in the regulation of Na+/H+ exchanger along the nephron luminal membrane.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Triphosphate; Amiloride; Animals; Cytochalasin B; Cytoskeleton; Cytosol; Enzyme Inhibitors; Intracellular Membranes; Ion Transport; Kidney Tubules, Distal; Kidney Tubules, Proximal; Kinetics; Nephrons; Phosphorylation; Protein Isoforms; Rabbits; Sodium; Sodium-Hydrogen Exchangers; Thionucleotides | 2001 |
Inhibition of Na+-H+ exchanger-3 interferes with apical receptor-mediated endocytosis via vesicle fusion.
Topics: Adenosine Triphosphate; Amiloride; Animals; Cells, Cultured; Endocytosis; Exocytosis; Kidney Tubules, Proximal; Opossums; Receptors, Cell Surface; Serum Albumin; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Transferrin | 2001 |
Regulation of tubular cell MCP-1 production by intracellular ions: a role for sodium and calcium.
Topics: Acid-Base Equilibrium; Amiloride; Animals; Calcium; Cell Survival; Cells, Cultured; Chemokine CCL2; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme-Linked Immunosorbent Assay; Fluorescent Dyes; Hydrogen-Ion Concentration; Kidney Tubules, Proximal; Lipopolysaccharides; Male; Ouabain; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium; Sodium-Potassium-Exchanging ATPase; Spectrometry, Fluorescence | 2001 |
Bafilomycin A(1) inhibits rhinovirus infection in human airway epithelium: effects on endosome and ICAM-1.
Topics: Amiloride; Anti-Bacterial Agents; Benzyl Alcohols; Cells, Cultured; Cytokines; DNA; Dose-Response Relationship, Drug; Endosomes; Enzyme Inhibitors; Female; Guanidines; Humans; Hydrogen-Ion Concentration; Intercellular Adhesion Molecule-1; Macrolides; Male; Middle Aged; NF-kappa B; Protein Binding; Proton-Translocating ATPases; Respiratory Mucosa; Respiratory Tract Infections; Rhinovirus; RNA, Messenger; Sodium-Hydrogen Exchangers; Trachea; Vacuolar Proton-Translocating ATPases; Virus Replication | 2001 |
Effects of SM-20550, a selective Na+-H+ exchange inhibitor, on the ion transport of myocardial mitochondria.
Topics: Amidines; Amiloride; Animals; Anti-Arrhythmia Agents; Biological Transport, Active; Calcium; Dose-Response Relationship, Drug; Drug Interactions; Fluorometry; Guinea Pigs; Hydrogen-Ion Concentration; In Vitro Techniques; Indoles; Intracellular Membranes; Ion Transport; Mitochondria, Heart; Sarcolemma; Sodium; Sodium-Calcium Exchanger; Sodium-Hydrogen Exchangers | 2001 |
Inhibition of the Na(+)/H(+) antiporter suppresses IL-12 p40 production by mouse macrophages.
Topics: Amiloride; Animals; Chemokine CCL4; Chemokine CXCL2; Chemokines; Diuretics; Drug Interactions; Enzyme Activation; Gene Silencing; Interleukin-12; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Macrophage Inflammatory Proteins; Macrophages, Peritoneal; Male; Methacrylates; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Sodium-Hydrogen Exchangers | 2001 |
Propofol increases myofilament Ca2+ sensitivity and intracellular pH via activation of Na+-H+ exchange in rat ventricular myocytes.
Topics: Actin Cytoskeleton; Amiloride; Ammonium Chloride; Anesthetics, Intravenous; Animals; Biotransformation; Calcium; Dose-Response Relationship, Drug; Heart Ventricles; Hydrogen-Ion Concentration; In Vitro Techniques; Myocardial Contraction; Myocardium; Myosins; Neuroprotective Agents; Propofol; Protein Kinase C; Rats; Sodium-Hydrogen Exchangers; Spectrometry, Fluorescence | 2001 |
pH regulation and buffering power in gastric smooth muscle.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acid-Base Equilibrium; Amiloride; Animals; Anti-Arrhythmia Agents; Buffers; Butyrates; Diuretics; Gastric Emptying; Gastric Mucosa; Guanidines; Guinea Pigs; Hydrogen-Ion Concentration; Methylamines; Muscle, Smooth; Rats; Sodium; Sulfones | 2001 |
The Na(+)/H(+) exchanger SM-20220 attenuates ischemic injury in in vitro and in vivo models.
Topics: Amides; Amiloride; Animals; Brain Ischemia; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Indoles; Infarction, Middle Cerebral Artery; L-Lactate Dehydrogenase; Male; Neuroglia; Neurons; Neuroprotective Agents; Pregnancy; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers | 2001 |
Rapid acid extrusion response triggered by alpha(1) adrenoceptor in CHO cells.
Topics: Acids; Adrenergic alpha-Agonists; Amiloride; Animals; CHO Cells; Cricetinae; Guanidines; Humans; Norepinephrine; Receptors, Adrenergic, alpha; Sodium-Hydrogen Exchangers; Sulfones | 2001 |
Intracellular pH changes in human aortic smooth muscle cells in response to fluid shear stress.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Amiloride; Aorta; Humans; Hydrogen-Ion Concentration; Muscle, Smooth, Vascular; Pulsatile Flow; Regional Blood Flow; Signal Transduction; Stress, Mechanical | 1997 |
Localization and functional characterization of Na+/H+ exchanger isoform NHE4 in rat thick ascending limbs.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Biological Transport; Fluorescent Antibody Technique; Guanidines; Isomerism; Loop of Henle; Membrane Proteins; Nephrons; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Sulfones | 2001 |
Propofol protection of sodium-hydrogen exchange activity sustains glutamate uptake during oxidative stress.
Topics: Amiloride; Anesthetics, Intravenous; Animals; Astrocytes; Bicarbonates; Cells, Cultured; Free Radical Scavengers; Glutamic Acid; Glutathione; Hydrogen-Ion Concentration; Microscopy, Fluorescence; Neuroprotective Agents; Oxidative Stress; Propofol; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; tert-Butylhydroperoxide; Tritium; Vitamin E | 2001 |
Amiloride derivatives are potent blockers of KATP channels.
Topics: Amiloride; Animals; ATP-Binding Cassette Transporters; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Electrophysiology; Heart; KATP Channels; Membrane Potentials; Mice; Myocardium; Oocytes; Plasmids; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; RNA, Complementary; Sodium-Hydrogen Exchangers; Uncoupling Agents; Xenopus | 2001 |
Inhibition of Na superset+/H superset+ exchange decreases albumin-induced NF-kappaB activation in renal proximal tubular cell lines (OK and LLC-PK1 cells).
Topics: Amiloride; Animals; Cell Line; Chlorpromazine; DNA; Endocytosis; Guanidines; Kidney Tubules, Proximal; LLC-PK1 Cells; NF-kappa B; Opossums; Serum Albumin, Bovine; Sodium-Hydrogen Exchangers; Sulfones; Swine; Tetradecanoylphorbol Acetate | 2001 |
Role of NHE isoforms in mediating bicarbonate reabsorption along the nephron.
Topics: Absorption; Amiloride; Animals; Bicarbonates; Biological Transport; Culture Techniques; Guanidines; Kidney Tubules, Distal; Kidney Tubules, Proximal; Loop of Henle; Male; Methacrylates; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sulfones | 2001 |
Dehydroascorbic acid uptake by coronary artery smooth muscle: effect of intracellular acidification.
Topics: Adenosine Triphosphate; Amiloride; Animals; Anti-Arrhythmia Agents; Biological Transport; Carbon Radioisotopes; Cells, Cultured; Coronary Vessels; Dehydroascorbic Acid; Guanidines; Hydrogen-Ion Concentration; Kinetics; Muscle, Smooth, Vascular; Sulfones; Swine | 2002 |
Basolateral membrane Cl(-)-, Na(+)-, and K(+)-coupled base transport mechanisms in rat MTALH.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Barium; Biological Transport, Active; Buffers; Chloride-Bicarbonate Antiporters; Electrophysiology; Epithelial Cells; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Loop of Henle; Male; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Chloride Symporters | 2002 |
Intestinal NaCl transport in NHE2 and NHE3 knockout mice.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Biological Transport; Chlorine; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Gene Expression; Intestinal Absorption; Jejunum; Mice; Mice, Knockout; Radioisotopes; Sodium Chloride; Sodium Radioisotopes; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers | 2002 |
Inhibitors of NHE-1 Na+/H+ exchange reduce mouse intraocular pressure.
Topics: Administration, Topical; Amiloride; Animals; Antihypertensive Agents; Aqueous Humor; Bumetanide; Diuretics; Electrophysiology; Female; Intraocular Pressure; Male; Mice; Sodium-Hydrogen Exchangers; Sulfonamides; Thiophenes | 2002 |
Apical Na+/H+ exchange near the base of mouse colonic crypts.
Topics: Amiloride; Animals; Cell Membrane; Chlorides; Colon; Fatty Acids, Volatile; Fluoresceins; Fluorescent Antibody Technique; Hydrogen-Ion Concentration; Intestinal Mucosa; Mice; Mice, Inbred ICR; Sodium-Hydrogen Exchangers | 2002 |
Expression and function of sodium transporters in two opossum kidney cell clonal sublines.
Topics: Amiloride; Animals; Aromatic-L-Amino-Acid Decarboxylases; Biological Transport; Catechol O-Methyltransferase; Clone Cells; Diuretics; Epithelial Cells; Hypertension, Renal; Immunoblotting; Kidney; Leucine; Levodopa; LLC-PK1 Cells; Methylglucosides; Microscopy, Electron, Scanning; Opossums; p-Aminohippuric Acid; Parathyroid Hormone; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase; Swine | 2002 |
Mitochondrial damage during ischemia determines post-ischemic contractile dysfunction in perfused rat heart.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Cytochrome c Group; In Vitro Techniques; Male; Membrane Potentials; Mitochondria; Myocardial Ischemia; Myocardial Reperfusion; Oxidative Phosphorylation; Rats; Rats, Wistar; Sodium; Tetrodotoxin | 2002 |
Loss of cell volume regulation during metabolic inhibition in renal epithelial cells (A6): role of intracellular pH.
Topics: Acids; Amiloride; Ammonium Chloride; Animals; Antimetabolites; Biological Transport; Cell Line; Deoxyglucose; Epithelial Cells; Hydrogen-Ion Concentration; Hypotonic Solutions; Intracellular Membranes; Kidney; Sodium; Sodium Cyanide | 2002 |
Cytostatic potential of novel agents that inhibit the regulation of intracellular pH.
Topics: Adenocarcinoma; Amiloride; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Division; Chloride-Bicarbonate Antiporters; Drug Design; Drug Screening Assays, Antitumor; Guanidines; Humans; Hydrogen-Ion Concentration; Intracellular Fluid; Mammary Neoplasms, Experimental; Neoplasm Proteins; Sodium-Hydrogen Exchangers; Sulfones; Tumor Cells, Cultured; Tumor Stem Cell Assay | 2002 |
Glucose stimulates O2 consumption, NOS, and Na/H exchange in diabetic rat proximal tubules.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Citrulline; Diabetes Mellitus, Experimental; Diabetic Ketoacidosis; Enzyme Inhibitors; Glucose; Hyperglycemia; Kidney Tubules, Proximal; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oligomycins; Ouabain; Oxygen Consumption; Rats; Rats, Wistar; Rubidium Radioisotopes; Sodium-Hydrogen Exchangers; Uncoupling Agents | 2002 |
Apical H(+)/base transporters mediating bicarbonate absorption and pH(i) regulation in the OMCD.
Topics: Acid-Base Equilibrium; Acids; Amiloride; Animals; Bicarbonates; Biological Transport; H(+)-K(+)-Exchanging ATPase; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney Tubules, Collecting; Microscopy, Confocal; Proton-Translocating ATPases; Rabbits; Sodium; Sodium-Bicarbonate Symporters | 2002 |
PTH stimulates a Cl(-)-dependent and EIPA-sensitive current in chick proximal tubule cells in culture.
Topics: Amiloride; Animals; Animals, Newborn; Biological Transport; Calcium Channel Blockers; Cells, Cultured; Chickens; Chlorides; Electric Conductivity; Electrophysiology; Kidney Tubules, Proximal; Osmolar Concentration; Parathyroid Hormone; Sodium-Hydrogen Exchangers | 2003 |
Effect of protein kinase C activation on Na+-H+ exchange in erythrocytes of frog Rana temporaria.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Biological Transport; Carcinogens; Enzyme Activation; Enzyme Inhibitors; Erythrocytes; Phosphoprotein Phosphatases; Protein Kinase C; Rana temporaria; Sodium; Sodium Fluoride; Sodium Radioisotopes; Sodium-Hydrogen Exchangers; Staurosporine; Tetradecanoylphorbol Acetate | 2003 |
Antifibrogenic effects of canrenone, an antialdosteronic drug, on human hepatic stellate cells.
Topics: Aldosterone; Amiloride; Calcium; Canrenone; Cell Division; Cell Movement; Cells, Cultured; Extracellular Matrix Proteins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Guanidines; Humans; Hydrogen-Ion Concentration; Intracellular Membranes; Liver; Liver Cirrhosis; Mineralocorticoid Receptor Antagonists; Phosphatidylinositol 3-Kinases; Phosphorylation; Platelet-Derived Growth Factor; Protein-Tyrosine Kinases; Signal Transduction; Sodium-Hydrogen Exchangers; Sulfones; Thrombin | 2003 |
Mutations of Arg440 and Gly455/Gly456 oppositely change pH sensing of Na+/H+ exchanger 1.
Topics: Amiloride; Arginine; Biological Transport; Cell Line; Extracellular Space; Glycine; Humans; Hydrogen-Ion Concentration; Molecular Sequence Data; Mutagenesis; Neuroprotective Agents; Protein Structure, Tertiary; Protons; Sequence Homology, Amino Acid; Sodium; Sodium-Hydrogen Exchangers | 2003 |
[3H]-DA release evoked by low pH medium and internal H+ accumulation in rat hypothalamic synaptosomes: involvement of calcium ions.
Topics: Amiloride; Animals; Calcium; Dopamine; Extracellular Space; Hydrogen-Ion Concentration; Hypothalamus; In Vitro Techniques; Ionophores; Male; Neuroprotective Agents; Nigericin; Potassium Chloride; Protons; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; Synaptosomes | 2003 |
Role of Na+/H+ exchanger in acetylcholine-mediated pulmonary artery contraction of spontaneously hypertensive rats.
Topics: Acetylcholine; Amiloride; Animals; Calcium; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Female; Hypertension; Imidazoles; In Vitro Techniques; Indoles; Male; Maleimides; Muscarinic Agonists; Muscarinic Antagonists; Neostigmine; Protein Kinase C; Pulmonary Artery; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Muscarinic; Sodium; Sodium-Calcium Exchanger; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase; Species Specificity; Thiourea; Vasoconstriction; Vasodilator Agents | 2003 |
Differential sensitivity of human monocytes and macrophages to ANP: a role of intracellular pH on reactive oxygen species production through the phospholipase involvement.
Topics: Amiloride; Anti-Arrhythmia Agents; Atrial Natriuretic Factor; Cells, Cultured; Chromatography, Thin Layer; Diglycerides; DNA Primers; Guanylate Cyclase; Humans; Hydrogen-Ion Concentration; Macrophages; Monocytes; Phosphatidic Acids; Reactive Oxygen Species; Receptors, Atrial Natriuretic Factor; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sensitivity and Specificity; Sodium-Hydrogen Exchangers; Type C Phospholipases | 2003 |
Intracellular pH regulation in U937 human monocytes: roles of V-ATPase and Na+/H+ exchange.
Topics: Amiloride; Anti-Bacterial Agents; Cell Membrane; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Intracellular Fluid; Macrolides; Monocytes; Neuroprotective Agents; Sodium-Hydrogen Exchangers; U937 Cells; Vacuolar Proton-Translocating ATPases | 2003 |
Inhibition of erythrocyte cation channels and apoptosis by ethylisopropylamiloride.
Topics: Amiloride; Annexins; Apoptosis; Cations; Cell Size; Dose-Response Relationship, Drug; Erythrocytes; Guanidines; Humans; In Vitro Techniques; Ion Channels; Osmotic Pressure; Patch-Clamp Techniques; Sulfones | 2003 |
Non-genomic regulation of intermediate conductance potassium channels by aldosterone in human colonic crypt cells.
Topics: Aldosterone; Amiloride; Colon; Epithelial Cells; Gene Expression; Humans; Hydrogen-Ion Concentration; Intermediate-Conductance Calcium-Activated Potassium Channels; Intestinal Mucosa; Ion Channel Gating; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Calcium-Activated; RNA, Messenger; Sodium-Hydrogen Exchangers | 2003 |
Endolymphatic sodium homeostasis by Reissner's membrane.
Topics: Amiloride; Animals; Bumetanide; Cochlear Duct; Colforsin; Diuretics; Dose-Response Relationship, Drug; Drug Interactions; Electrochemistry; Electrodes; Endolymph; Enzyme Inhibitors; Epithelial Cells; Genistein; Gerbillinae; Homeostasis; In Vitro Techniques; Ion Transport; Membrane Potentials; Neuroprotective Agents; Ouabain; Potassium Channel Blockers; Sodium; Vibration | 2003 |
Critical role for NHE1 in intracellular pH regulation in pancreatic acinar cells.
Topics: Acids; Amiloride; Animals; Bicarbonates; Buffers; Calcium Signaling; Carbachol; Hydrogen-Ion Concentration; Intracellular Membranes; Mice; Mice, Knockout; Muscarinic Agonists; Pancreas; Protons; Sodium-Hydrogen Exchangers | 2003 |
Electrophysiological properties of the Plasmodium Falciparum-induced cation conductance of human erythrocytes.
Topics: Amiloride; Animals; Calcium Channels; Cations; Erythrocytes; Humans; Ion Transport; Patch-Clamp Techniques; Plasmodium falciparum | 2003 |
Ethyl isopropyl amiloride inhibits smooth muscle cell proliferation and migration by inducing apoptosis and antagonizing urokinase plasminogen activator activity.
Topics: Amiloride; Animals; Aorta, Abdominal; Apoptosis; Cell Movement; Dose-Response Relationship, Drug; Enzyme Inhibitors; Growth Inhibitors; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rabbits; Urokinase-Type Plasminogen Activator | 2003 |
Demonstration of a functional apical sodium hydrogen exchanger in isolated rat gastric glands.
Topics: Amiloride; Animals; Blotting, Western; Cell Membrane; Enzyme Inhibitors; Gastric Mucosa; Guanidines; H(+)-K(+)-Exchanging ATPase; Histamine; Hydrogen-Ion Concentration; Immunohistochemistry; In Vitro Techniques; Intracellular Membranes; Isoenzymes; Methacrylates; Omeprazole; Parietal Cells, Gastric; Perfusion; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers | 2003 |
Na+ overload during ischemia and reperfusion in rat hearts: comparison of the Na+/H+ exchange blockers EIPA, cariporide and eniporide.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Calcium; Guanidines; Hydrogen-Ion Concentration; Ischemia; Magnetic Resonance Spectroscopy; Male; Myocardial Contraction; Myocardium; Perfusion; Phosphates; Rats; Rats, Wistar; Reperfusion Injury; Sodium; Sodium-Hydrogen Exchangers; Sulfones; Time Factors | 2003 |
Dependence of Plasmodium falciparum in vitro growth on the cation permeability of the human host erythrocyte.
Topics: Amiloride; Animals; Calcium; Cations; Cell Membrane; Cell Membrane Permeability; Chlorides; Electric Conductivity; Erythrocytes; Humans; Iron Chelating Agents; Patch-Clamp Techniques; Phosphatidylserines; Plasmodium falciparum; Sodium | 2003 |
The Na+/H+ exchange inhibitor: a new therapeutic approach for hepatic ischemia injury in rats.
Topics: Adenosine Triphosphate; Amiloride; Animals; Hepatic Artery; Ischemia; Kinetics; Liver; Liver Circulation; Male; Portal Vein; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers | 2003 |
Sodium and chloride transport in soft water and hard water acclimated zebrafish (Danio rerio).
Topics: Amiloride; Animals; Biological Transport; Blotting, Western; Chlorides; Down-Regulation; Ethoxzolamide; Fresh Water; Gills; Immunohistochemistry; Kinetics; Macrolides; Proton Pump Inhibitors; Proton Pumps; Sodium; Zebrafish | 2003 |
Stimulation of NHE3 in OKP cells by an autocrine mechanism.
Topics: Acidosis; Amiloride; Angiotensin II; Animals; Autocrine Communication; Benzoquinones; Cell Line; Culture Media, Conditioned; Dose-Response Relationship, Drug; Endothelin B Receptor Antagonists; Endothelin-1; Hydrogen-Ion Concentration; Kidney; Lactams, Macrocyclic; Oligopeptides; Opossums; Piperidines; Potassium; Protein-Tyrosine Kinases; Quinones; Receptor, Endothelin B; Rifabutin; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Time Factors | 2004 |
Intracellular acidification by inhibition of the Na+/H+-exchanger leads to caspase-independent death of cerebellar granule neurons resembling paraptosis.
Topics: Acidosis; Adenoviridae; Amiloride; Animals; Apoptosis; Caspases; Cell Survival; Cells, Cultured; Cerebellum; Cycloheximide; Dose-Response Relationship, Drug; Guanidines; Hydrogen-Ion Concentration; Neurons; Potassium; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Sulfones | 2004 |
Cadmium induces both pyruvate kinase and Na+/H+ exchanger activity through protein kinase C mediated signal transduction, in isolated digestive gland cells of Mytilus galloprovincialis (L.).
Topics: Amiloride; Animals; Bivalvia; Cadmium; Digestive System; Epinephrine; Greece; Hydrogen-Ion Concentration; Isoproterenol; Naphthalenes; Phenylephrine; Phorbol Esters; Prazosin; Propranolol; Protein Kinase C; Pyruvate Kinase; Signal Transduction; Sodium-Hydrogen Exchangers; Staurosporine | 2004 |
Differential regulation of Na+/H+ exchange isoform activities by enteropathogenic E. coli in human intestinal epithelial cells.
Topics: Amiloride; Caco-2 Cells; Cell Membrane; Enteritis; Escherichia coli Infections; Escherichia coli Proteins; Humans; Intestinal Absorption; Intestinal Mucosa; Intracellular Membranes; Osmotic Pressure; Protein Isoforms; Sodium; Sodium-Hydrogen Exchangers; Time Factors | 2004 |
Inhibition of carcinogen-bioactivating cytochrome P450 1 isoforms by amiloride derivatives.
Topics: Amiloride; Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Enzyme Inhibitors; Gene Expression; Isoenzymes; Male; Rats; Rats, Sprague-Dawley | 2004 |
Activation of the apical Na+/H+ exchanger NHE3 by formate: a basis of enhanced fluid and electrolyte reabsorption by formate in the kidney.
Topics: Absorption; Acetates; Acids; Alkalies; Amiloride; Animals; Bicarbonates; Body Fluids; Carbon Dioxide; Cell Membrane; Chlorides; Electrolytes; Formates; Hydrogen-Ion Concentration; Kidney; Kidney Medulla; Kidney Tubules, Collecting; Kidney Tubules, Proximal; Mice; Sodium; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers | 2004 |
CD44 interaction with Na+-H+ exchanger (NHE1) creates acidic microenvironments leading to hyaluronidase-2 and cathepsin B activation and breast tumor cell invasion.
Topics: Amides; Amiloride; Animals; Breast Neoplasms; Cathepsin B; Caveolin 1; Caveolins; Cell Line, Tumor; Endosomes; Enzyme Inhibitors; Humans; Hyaluronan Receptors; Hyaluronic Acid; Hyaluronoglucosaminidase; Hydrogen-Ion Concentration; Immunoglobulin G; Intracellular Signaling Peptides and Proteins; Lysosomes; Membrane Microdomains; Membrane Proteins; Neoplasm Invasiveness; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; Rats; rho-Associated Kinases; RNA, Small Interfering; Sodium-Hydrogen Exchangers | 2004 |
Inhibition of bicarbonate reabsorption in the rat proximal tubule by activation of luminal P2Y1 receptors.
Topics: Adenine; Amiloride; Animals; Bicarbonates; Dose-Response Relationship, Drug; Enzyme Inhibitors; Kidney Tubules, Proximal; Macrolides; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Signal Transduction; Uridine | 2004 |
Endocardial endothelium modulates subendocardial pH(i) of rabbit papillary muscles: role of transendothelial HCO(3)(-) transport.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Ammonium Chloride; Animals; Anti-Arrhythmia Agents; Bicarbonates; Endocardium; Endothelial Cells; Hydrogen-Ion Concentration; In Vitro Techniques; Ion Channels; Myocytes, Cardiac; Papillary Muscles; Rabbits; Signal Transduction | 2004 |
Acidification reduces mitochondrial calcium uptake in rat cardiac mitochondria.
Topics: Acids; Amiloride; Animals; Anti-Arrhythmia Agents; Calcium; Choline; Cytosol; Hydrogen-Ion Concentration; Male; Membrane Potentials; Mitochondria; Myocytes, Cardiac; Potassium Chloride; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers | 2004 |
Rapid nongenomic effects of 3,5,3'-triiodo-L-thyronine on the intracellular pH of L-6 myoblasts are mediated by intracellular calcium mobilization and kinase pathways.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Calcium; Cells, Cultured; Enzyme Inhibitors; Hydrogen-Ion Concentration; MAP Kinase Signaling System; Muscle, Skeletal; Myoblasts; Protein Kinase C; Rats; Sodium-Hydrogen Exchangers; Triiodothyronine | 2004 |
Bidirectional regulation of renal cortical Na+,K+-ATPase by protein kinase C.
Topics: Amiloride; Animals; Arachidonic Acids; Brefeldin A; Cytochrome P-450 Enzyme System; Endocytosis; Enzyme Activation; Enzyme Inhibitors; Kidney Cortex; Kinetics; Male; Models, Biological; Nocodazole; Okadaic Acid; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylinositol 3-Kinases; Protein Kinase C; Rats; Rats, Wistar; Sodium; Sodium-Potassium-Exchanging ATPase; Staurosporine; Tetradecanoylphorbol Acetate | 2004 |
Involvement of Na+/H+ exchanger in desmopressin-induced platelet procoagulant response.
Topics: Amiloride; Blood Coagulation; Blood Platelets; Cell Membrane; Cell Size; Collagen; Deamino Arginine Vasopressin; Humans; In Vitro Techniques; Monensin; Phosphatidylserines; Platelet Activation; Platelet Count; Sodium-Hydrogen Exchangers; Thrombin | 2004 |
An IkappaB-beta COOH terminal region protein is essential for the proliferation of CHO cells under acidic stress.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acids; Adaptation, Physiological; Amiloride; Animals; Anti-Arrhythmia Agents; Base Sequence; Cell Division; Chlorocebus aethiops; CHO Cells; Clone Cells; COS Cells; Cricetinae; Cricetulus; Cytosol; DNA, Complementary; Female; Homeostasis; Hydrogen-Ion Concentration; I-kappa B Proteins; Macrolides; Molecular Sequence Data; Mutagenesis; Ovary; Protein Structure, Tertiary; Transfection | 2005 |
Novel antiinflammatory vascular benefits of systemic and stent-based delivery of ethylisopropylamiloride.
Topics: Amiloride; Animals; Anti-Inflammatory Agents; Aorta; Apolipoproteins E; Arteriosclerosis; Cell Adhesion; Cell Line; Cell Nucleus; Constriction, Pathologic; Dietary Fats; Down-Regulation; Endothelial Cells; Iliac Artery; Mice; Mice, Knockout; Monocytes; NF-kappa B; Protein Transport; Rabbits; Stents; Tunica Intima; Vascular Cell Adhesion Molecule-1 | 2004 |
Muscarinic activation of Na+-dependent ion transporters and modulation by bicarbonate in rat submandibular gland acinus.
Topics: Acetylcholine; Amiloride; Animals; Bicarbonates; Bumetanide; Carrier Proteins; Cholinergic Agents; Electrophysiology; In Vitro Techniques; Intracellular Membranes; Ion Transport; Ions; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Sodium; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Hydrogen Exchangers; Sodium-Potassium-Chloride Symporters; Submandibular Gland | 2005 |
Different contributions of endothelin-A and endothelin-B receptors in postischemic cardiac dysfunction and norepinephrine overflow in rat hearts.
Topics: Amiloride; Animals; Animals, Genetically Modified; Atrasentan; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Gene Deletion; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Norepinephrine; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Regional Blood Flow; Ventricular Pressure | 2005 |
Na+/H+ exchanger activity is increased in doxorubicin-resistant human colon cancer cells and its modulation modifies the sensitivity of the cells to doxorubicin.
Topics: Amiloride; Colonic Neoplasms; Doxorubicin; Drug Resistance, Neoplasm; HT29 Cells; Humans; Hydrogen-Ion Concentration; Monensin; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 2005 |
Heat-induced changes in intracellular Na+, pH and bioenergetic status in superfused RIF-1 tumour cells determined by 23Na and 31P magnetic resonance spectroscopy.
Topics: Amiloride; Cell Line, Tumor; Fibrosarcoma; Humans; Hydrogen-Ion Concentration; Hyperthermia, Induced; Magnetic Resonance Spectroscopy; Phosphorus Isotopes; Sodium; Sodium-Hydrogen Exchangers | 2005 |
Impaired regulation of pH homeostasis by oxidative stress in rat brain capillary endothelial cells.
Topics: Acidosis; Amiloride; Ammonium Chloride; Animals; Blood-Brain Barrier; Buffers; Cells, Cultured; Culture Media; Endothelial Cells; HEPES; Homeostasis; Hydrogen Peroxide; Hydrogen-Ion Concentration; Neuroprotective Agents; Oxidants; Oxidative Stress; Rats; Rats, Inbred Lew; Sodium; Sodium-Hydrogen Exchangers | 2005 |
Dual modes of 5-(N-ethyl-N-isopropyl)amiloride modulation of apical dipeptide uptake in the human small intestinal epithelial cell line Caco-2.
Topics: Amiloride; Analysis of Variance; Biological Transport; Caco-2 Cells; Cation Transport Proteins; Cell Survival; Dipeptides; Dose-Response Relationship, Drug; Epithelial Cells; Guanidines; Humans; Hydrogen-Ion Concentration; Intestine, Small; Membrane Potentials; Membrane Proteins; Methacrylates; Peptide Transporter 1; Protein Isoforms; Protons; Sodium; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sulfones; Symporters | 2005 |
Zinc and 17beta-estradiol induce modifications in Na+/H+ exchanger and pyruvate kinase activity through protein kinase C in isolated mantle/gonad cells of Mytilus galloprovincialis.
Topics: Amiloride; Animal Structures; Animals; Bivalvia; Cells, Cultured; Drug Combinations; Enzyme Activation; Estradiol; Female; Ovary; Protein Kinase C; Pyruvate Kinase; Signal Transduction; Sodium-Hydrogen Exchangers; Water Pollutants, Chemical; Zinc | 2005 |
Properties of motility in Bacillus subtilis powered by the H+-coupled MotAB flagellar stator, Na+-coupled MotPS or hybrid stators MotAS or MotPB.
Topics: Amiloride; Bacillus subtilis; Bacterial Proteins; Flagella; Ion Channel Gating; Ion Channels; Molecular Motor Proteins; Mutation; Protons; Sodium | 2005 |
Rho GTPases dictate the mobility of the Na/H exchanger NHE3 in epithelia: role in apical retention and targeting.
Topics: Amiloride; Animals; Cell Membrane; Cells, Cultured; Cytoskeleton; Dogs; Epithelial Cells; Fluorescence Recovery After Photobleaching; Hydrogen-Ion Concentration; Kidney Tubules; Microscopy, Electron; Models, Molecular; Protein Transport; rho GTP-Binding Proteins; Sodium; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers | 2005 |
Axial flow modulates proximal tubule NHE3 and H-ATPase activities by changing microvillus bending moments.
Topics: Amiloride; Animals; Bicarbonates; Biological Transport; Cytochalasin D; In Vitro Techniques; Kidney Tubules, Proximal; Macrolides; Mice; Mice, Inbred C57BL; Mice, Knockout; Microvilli; Perfusion; Proton-Translocating ATPases; Sodium; Sodium Channel Blockers; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Torque | 2006 |
Differential contribution of troponin I phosphorylation sites to the endothelin-modulated contractile response.
Topics: Actin Cytoskeleton; Adenoviridae; Alanine; Amiloride; Animals; Binding Sites; Calcium; Cells, Cultured; Cluster Analysis; Cyclic AMP-Dependent Protein Kinases; DNA, Complementary; Endothelins; Hydrogen-Ion Concentration; Models, Statistical; Muscle Cells; Mutagenesis; Myocardial Contraction; Myocardium; Phosphorylation; Protein Kinase C; Rats; Sarcomeres; Serine; Threonine; Time Factors; Troponin I | 2005 |
Mechanisms for nongenomic and genomic effects of aldosterone on Na+/H+ exchange in vascular smooth muscle cells.
Topics: Aldosterone; Amiloride; Animals; Cells, Cultured; Eplerenone; Fluorescent Dyes; Genome; Hydrogen-Ion Concentration; Ion Transport; Kinetics; Mineralocorticoid Receptor Antagonists; Muscle, Smooth, Vascular; Rats; Sodium-Hydrogen Exchangers; Spironolactone | 2005 |
Control of intracellular trafficking of ICAM-1-targeted nanocarriers by endothelial Na+/H+ exchanger proteins.
Topics: Amiloride; Biological Transport; Egtazic Acid; Endocytosis; Endothelium, Vascular; Humans; Intercellular Adhesion Molecule-1; Kinetics; Nanostructures; Sodium-Hydrogen Exchangers; Thapsigargin | 2006 |
Chronic high glucose inhibits albumin reabsorption by lysosomal alkalinization in cultured porcine proximal tubular epithelial cells (LLC-PK1).
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Albumins; Amiloride; Animals; Epithelial Cells; Fluorescein-5-isothiocyanate; Glucose; Hydrogen-Ion Concentration; Kidney Tubules, Proximal; LLC-PK1 Cells; Lysosomes; Macrolides; Sus scrofa | 2006 |
Involvement of the Na+/H+ exchanger in membrane phosphatidylserine exposure during human platelet activation.
Topics: Amiloride; Blood Platelets; Calcium; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Membrane Lipids; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylserines; Platelet Activation; Receptor, PAR-1; Sodium; Sodium-Hydrogen Exchangers | 2006 |
The effect of acidosis on adenosine release from cultured rat forebrain neurons.
Topics: Acetates; Acidosis; Adenosine; Amiloride; Analysis of Variance; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Agonists; Fluoresceins; Hydrogen-Ion Concentration; Methylamines; Models, Biological; N-Methylaspartate; Neurons; Neuroprotective Agents; Prosencephalon; Purines; Rats; Time Factors; Tritium | 2006 |
Involvement of Na+/H+ exchanger in the calcium signaling in epimastigotes of Trypanosoma cruzi.
Topics: Amiloride; Animals; Calcium; Calcium Signaling; Hydrogen-Ion Concentration; Sodium-Calcium Exchanger; Tetradecanoylphorbol Acetate; Trypanosoma cruzi | 2006 |
NHE2 is the main apical NHE in mouse colonic crypts but an alternative Na+-dependent acid extrusion mechanism is upregulated in NHE2-null mice.
Topics: Acids; Amiloride; Animals; Cation Transport Proteins; Colon; Gene Expression Regulation; Membrane Proteins; Mice; Mice, Knockout; Sodium; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Up-Regulation | 2006 |
Cytotoxic mechanisms of Zn2+ and Cd2+ involve Na+/H+ exchanger (NHE) activation by ROS.
Topics: Acetylcysteine; Amiloride; Animals; Antimycin A; Antioxidants; Cadmium; Cadmium Poisoning; Cell Survival; Gills; Hydrogen-Ion Concentration; Mytilus; Naphthalenes; Oxidants; PPAR gamma; Protein Kinase Inhibitors; Pyruvic Acid; Reactive Oxygen Species; Receptors, Adrenergic; Rosiglitazone; Rotenone; Sodium-Hydrogen Exchangers; Thiazolidinediones; Water Pollutants, Chemical; Zinc | 2006 |
Effects of bafilomycin A1, a vacuolar type H+ ATPase inhibitor, on the thermosensitivity of a human pancreatic cancer cell line.
Topics: Amiloride; Animals; Antineoplastic Combined Chemotherapy Protocols; Body Temperature Regulation; Cell Line, Tumor; Cell Membrane; Combined Modality Therapy; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Hyperthermia, Induced; Macrolides; Male; Mice; Mice, Nude; Pancreatic Neoplasms; Proton-Translocating ATPases; Sodium-Hydrogen Exchangers; Transplantation, Heterologous | 2006 |
PGE2-induced apoptotic cell death in K562 human leukaemia cells.
Topics: Acid Sensing Ion Channels; Amiloride; Annexin A5; Apoptosis; Calcium; Caspases; Cell Death; Cell Size; Cytosol; Dinoprostone; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Activation; Gene Silencing; Humans; Ion Channels; K562 Cells; Membrane Potentials; Membrane Proteins; Mitochondria; Nerve Tissue Proteins; Phosphatidylserines; Sodium Channels; TRPC Cation Channels | 2006 |
Reduction of intracellular pH inhibits the expression of VEGF in K562 cells after targeted inhibition of the Na+/H+ exchanger.
Topics: Amiloride; Blotting, Western; Gene Expression; Humans; Hydrogen-Ion Concentration; Immunoenzyme Techniques; K562 Cells; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium-Hydrogen Exchangers; Vascular Endothelial Growth Factor A | 2007 |
Apical electrolyte concentration modulates barrier function and tight junction protein localization in bovine mammary epithelium.
Topics: Amiloride; Animals; Biological Transport; Cattle; Cell Membrane; Cell Membrane Permeability; Cells, Cultured; Culture Media; Electric Impedance; Electrolytes; Epithelium; Female; Mammary Glands, Animal; Membrane Proteins; Occludin; Osmolar Concentration; Phosphoproteins; Sodium; Sodium Channel Blockers; Tight Junctions; Tissue Distribution; Tumor Necrosis Factor-alpha; Zonula Occludens-1 Protein | 2007 |
Transporters involved in regulation of intracellular pH in primary cultured rat brain endothelial cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Ammonium Chloride; Animals; Blood-Brain Barrier; Cells, Cultured; Chloride-Bicarbonate Antiporters; Endothelium, Vascular; Hydrogen-Ion Concentration; Mathematics; Neuroprotective Agents; Rats; Rats, Wistar; Sodium Chloride Symporters; Sodium-Bicarbonate Symporters; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase | 2006 |
Molecular characterization of sodium/proton exchanger 3 (NHE3) from the yellow fever vector, Aedes aegypti.
Topics: Aedes; Amiloride; Amino Acid Sequence; Animals; Animals, Genetically Modified; Cell Line; Cricetinae; Cricetulus; Genetic Complementation Test; Hydrogen-Ion Concentration; Immunohistochemistry; Insect Proteins; Insect Vectors; Ion Transport; Larva; Malpighian Tubules; Molecular Sequence Data; Protein Structure, Tertiary; Saccharomyces cerevisiae; Sequence Alignment; Sodium; Sodium Channel Blockers; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers | 2006 |
Relative contribution of V-H+ATPase and NA+/H+ exchanger to bicarbonate reabsorption in proximal convoluted tubules of old rats.
Topics: Aging; Amiloride; Animals; Bicarbonates; Blotting, Western; Hydrogen-Ion Concentration; Kidney Tubules, Proximal; Microvilli; Rats; Sodium Channel Blockers; Sodium-Hydrogen Exchangers; Vacuolar Proton-Translocating ATPases | 2006 |
Effects of Na+/H+ exchanger inhibitors on subcellular localisation of endocytic organelles and intracellular dynamics of protein transduction domains HIV-TAT peptide and octaarginine.
Topics: Amiloride; Cell Survival; Dose-Response Relationship, Drug; Endocytosis; Endosomes; Flow Cytometry; Fluorescent Dyes; Gene Products, tat; HeLa Cells; Humans; Lysosomal Membrane Proteins; Lysosomal-Associated Membrane Protein 2; Lysosomes; Membrane Proteins; Microscopy, Confocal; Microscopy, Fluorescence; Oligopeptides; Pinocytosis; Sodium-Hydrogen Exchangers; Time Factors; Vesicular Transport Proteins | 2006 |
Positive inotropic effects of carbon monoxide-releasing molecules (CO-RMs) in the isolated perfused rat heart.
Topics: Alkaloids; Amiloride; Animals; Benzophenanthridines; Boranes; Calcium Channel Blockers; Carbon Monoxide; Carbonates; Cardiotonic Agents; Enzyme Inhibitors; Heart; Kinetics; Male; Myocardium; Nifedipine; Organometallic Compounds; Rats; Rats, Inbred Lew; Signal Transduction | 2006 |
Colony-stimulating factor-1 increases osteoclast intracellular pH and promotes survival via the electroneutral Na/HCO3 cotransporter NBCn1.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Alkalies; Amiloride; Animals; Bicarbonates; Carbon Dioxide; Caspase Inhibitors; Cell Separation; Cell Survival; Cells, Cultured; Enzyme Inhibitors; Hydrogen-Ion Concentration; Intracellular Fluid; Macrolides; Macrophage Colony-Stimulating Factor; Mice; Mice, Inbred Strains; Osteoclasts; Protons; Rats; Sodium; Sodium-Bicarbonate Symporters | 2007 |
Vectorial bicarbonate transport by Capan-1 cells: a model for human pancreatic ductal secretion.
Topics: Adenosine Triphosphate; Amiloride; Animals; Antiporters; Bicarbonates; Cells, Cultured; Chlorine; Epithelial Cells; Guinea Pigs; Humans; Membrane Proteins; Models, Biological; Occludin; Pancreatic Ducts; Protons; RNA, Messenger; Sodium; Sodium Bicarbonate; Uridine Triphosphate | 2006 |
Delay of acute intracellular pH recovery after acidosis decreases endothelial cell activation.
Topics: Acidosis; Amiloride; Calcium; Cell Adhesion; Cells, Cultured; Chloride-Bicarbonate Antiporters; Cyclic AMP; Endothelial Cells; Endothelium, Vascular; Exocytosis; Guanidines; Histamine; Humans; Hydrogen-Ion Concentration; Interleukin-8; Intracellular Fluid; Kinetics; Linear Models; Methacrylates; P-Selectin; Platelet Adhesiveness; Reperfusion Injury; Sodium-Hydrogen Exchangers; Sulfones; Umbilical Veins; von Willebrand Factor | 2007 |
The role played by endocytosis in albumin-induced secretion of TGF-beta1 by proximal tubular epithelial cells.
Topics: Amiloride; Animals; Cell Line; Clone Cells; Endocytosis; Epithelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney Tubules, Proximal; Low Density Lipoprotein Receptor-Related Protein-2; Opossums; Receptors, Transforming Growth Factor beta; Serum Albumin; Simvastatin; Sodium-Hydrogen Exchangers; Transforming Growth Factor beta1 | 2007 |
Vitamin C transport and SVCT1 transporter expression in chick renal proximal tubule cells in culture.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Ascorbic Acid; Cells, Cultured; Chickens; Electrophysiology; Gene Expression Regulation; Humans; Kidney Tubules, Proximal; Nitrobenzoates; Organic Anion Transporters, Sodium-Dependent; Quercetin; Sodium-Coupled Vitamin C Transporters; Symporters; Tetradecanoylphorbol Acetate | 2007 |
An improved in vitro model of human intestinal follicle-associated epithelium to study nanoparticle transport by M cells.
Topics: Amiloride; B-Lymphocytes; Caco-2 Cells; Cell Differentiation; Coculture Techniques; Drug Carriers; Epithelial Cells; Humans; Immunohistochemistry; Intestinal Mucosa; Microscopy, Confocal; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nanoparticles; Nystatin; Peyer's Patches; Pinocytosis; Polystyrenes; Reproducibility of Results; Temperature | 2007 |
Loss of calcineurin homologous protein-1 in chicken B lymphoma DT40 cells destabilizes Na+/H+ exchanger isoform-1 protein.
Topics: Amiloride; Animals; Calcium; Calcium-Binding Proteins; Cation Transport Proteins; Chickens; Down-Regulation; Gene Deletion; HeLa Cells; Humans; Lymphoma, B-Cell; Mutation; Myristic Acid; Opossums; Protein Binding; Protein Isoforms; Protein Processing, Post-Translational; RNA Interference; RNA, Messenger; RNA, Small Interfering; Sodium; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers | 2007 |
A vacuolar-type H+-ATPase and a Na+/H+ exchanger contribute to intracellular pH regulation in cockroach salivary ducts.
Topics: Acid-Base Equilibrium; Amiloride; Ammonium Chloride; Analysis of Variance; Animals; Cytophotometry; Dopamine; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Intracellular Fluid; Macrolides; Microelectrodes; Periplaneta; Salivary Ducts; Sodium-Hydrogen Exchangers; Vacuolar Proton-Translocating ATPases | 2007 |
Role of Na+/H+ exchanger in the pathogenesis of ischemic acute renal failure in mice.
Topics: Acute Kidney Injury; Amiloride; Animals; Endothelin-1; Kidney; Kidney Tubular Necrosis, Acute; Kidney Tubules; Male; Mice; Protective Agents; Reperfusion Injury; Sodium-Hydrogen Exchangers | 2007 |
Bicarbonate-dependent pH(i) regulation by chondrocytes within the superficial zone of bovine articular cartilage.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Ammonium Chloride; Animals; Bicarbonates; Cartilage, Articular; Cattle; Cells, Cultured; Chondrocytes; Fluorescent Antibody Technique; Hydrogen-Ion Concentration; Intracellular Fluid; Microscopy, Fluorescence; Sodium-Bicarbonate Symporters; Time Factors; Tissue Culture Techniques | 2007 |
pH-dependent toxicity of sulphur mustard in vitro.
Topics: Adaptation, Physiological; Amiloride; Animals; Caspase 3; Cell Death; Chemical Warfare Agents; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Extracellular Fluid; Female; Hydrogen-Ion Concentration; Intracellular Fluid; Mustard Gas; Sodium-Hydrogen Exchangers | 2007 |
The alpha2-adrenergic receptor agonist UK 14,304 inhibits secretin-stimulated ductal secretion by downregulation of the cAMP system in bile duct-ligated rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Amiloride; Animals; Anti-Arrhythmia Agents; Bicarbonates; Bile; Bile Duct Diseases; Bile Ducts, Intrahepatic; Brimonidine Tartrate; Chloride-Bicarbonate Antiporters; Chlorides; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Hepatocytes; Ligation; Liver; Male; Quinoxalines; Rats; Rats, Inbred F344; Receptors, Adrenergic, alpha-2; Secretin; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Yohimbine | 2007 |
Enhanced Na+/H+ exchange activity contributes to the pathogenesis of muscular dystrophy via involvement of P2 receptors.
Topics: Adenosine Triphosphate; Amiloride; Animals; Calcium; Cations, Divalent; Cells, Cultured; Cricetinae; Guanidines; Ion Transport; Mice; Mice, Inbred mdx; Muscle Fibers, Skeletal; Muscular Dystrophy, Animal; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Sodium; Sodium-Calcium Exchanger; Sodium-Hydrogen Exchangers; Sulfones | 2007 |
5-(N-ethyl-N-isopropyl)-amiloride enhances SMN2 exon 7 inclusion and protein expression in spinal muscular atrophy cells.
Topics: Alternative Splicing; Amiloride; Cell Line; Cell Survival; Cyclic AMP Response Element-Binding Protein; Enzyme Inhibitors; Exons; Humans; Hydrogen-Ion Concentration; Lymphocytes; Molecular Biology; Motor Neurons; Muscular Atrophy, Spinal; Nerve Tissue Proteins; Neuroprotective Agents; RNA Precursors; RNA Splicing; RNA-Binding Proteins; SMN Complex Proteins; Sodium-Hydrogen Exchangers; Survival of Motor Neuron 1 Protein; Survival of Motor Neuron 2 Protein; Transcription, Genetic | 2008 |
Lysophosphatidylserine increases membrane potentials in rat C6 glioma cells.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Amiloride; Animals; Cell Line, Tumor; Glioma; GTP-Binding Proteins; Lysophospholipids; Membrane Potentials; Rats; Receptors, G-Protein-Coupled | 2007 |
Cellular uptake of cell-penetrating peptides pVEC and transportan in plants.
Topics: Amiloride; Cell Membrane; Cell Membrane Permeability; Cells; Cytochalasins; Edible Grain; Endocytosis; Fluorescent Dyes; Galanin; Microscopy, Fluorescence; Nocodazole; Peptides; Protein Transport; Protoplasts; Recombinant Fusion Proteins; Seedlings; Sodium Azide; Wasp Venoms | 2008 |
Amiloride derivatives inhibit coxsackievirus B3 RNA replication.
Topics: Amiloride; Antiviral Agents; DNA-Directed RNA Polymerases; Enterovirus B, Human; Humans; Viral Proteins; Virus Replication | 2008 |
Impaired acid secretion in cortical collecting duct intercalated cells from H-K-ATPase-deficient mice: role of HKalpha isoforms.
Topics: Acids; Amiloride; Animals; Anti-Arrhythmia Agents; Diet; Female; Genotype; H(+)-K(+)-Exchanging ATPase; Hydrogen-Ion Concentration; Kidney Tubules, Collecting; Macrolides; Mice; Mice, Inbred C57BL; Mice, Knockout; Protein Isoforms; Proton-Translocating ATPases; Protons | 2008 |
Oxidative stress and the genomic regulation of aldosterone-stimulated NHE1 activity in SHR renal proximal tubular cells.
Topics: Aldosterone; Amiloride; Animals; Cell Line; Cytochalasin B; Dactinomycin; Gene Expression Regulation; Genome; Guanidines; Hydrogen Peroxide; Hydrogen-Ion Concentration; Immunoblotting; Kidney Tubules, Proximal; Methacrylates; Mifepristone; Oxidative Stress; Protein Isoforms; Rats; Rats, Inbred SHR; Receptors, Mineralocorticoid; RNA, Messenger; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Spironolactone; Sulfones | 2008 |
Transport activities involved in intracellular pH recovery following acid and alkali challenges in rat brain microvascular endothelial cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acids; Adenosine Triphosphate; Alkalies; Amiloride; Animals; Biological Transport; Brain; Carbonates; Cells, Cultured; Chlorides; Deoxyglucose; Endothelial Cells; Hydrogen-Ion Concentration; Microcirculation; Neuroprotective Agents; Rats; Rats, Wistar; Sodium; Vacuolar Proton-Translocating ATPases | 2008 |
Targeting splicing in spinal muscular atrophy.
Topics: Amiloride; Cyclic AMP Response Element-Binding Protein; Exons; Gene Expression Regulation; Genetic Predisposition to Disease; Genetic Therapy; Humans; Muscular Atrophy, Spinal; Nerve Tissue Proteins; RNA Splicing; RNA-Binding Proteins; Serine-Arginine Splicing Factors; SMN Complex Proteins | 2008 |
Blockade of epithelial sodium channels improves sperm motility in asthenospermia patients.
Topics: Amiloride; Animals; Asthenozoospermia; Blotting, Western; Case-Control Studies; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Fertility Agents, Male; Humans; Immunohistochemistry; Male; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Sperm Motility; Spermatozoa; Testis | 2009 |
Mitochondrial Complex I superoxide production is attenuated by uncoupling.
Topics: Amiloride; Animals; Cell Respiration; Dose-Response Relationship, Drug; Electron Transport Complex I; Glutamic Acid; Hydrogen Peroxide; Malates; Mitochondria, Liver; Models, Biological; Proton Pumps; Rats; Rats, Wistar; Succinic Acid; Superoxides; Uncoupling Agents | 2008 |
Lidocaine increases intracellular sodium concentration through a Na+-H+ exchanger in an identified Lymnaea neuron.
Topics: Amiloride; Anesthetics, Local; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Lidocaine; Lymnaea; Mepivacaine; Microscopy, Fluorescence; Neurons; Prilocaine; Sodium; Sodium-Hydrogen Exchangers; Up-Regulation | 2008 |
Late expression of Na+/H+ exchanger 1 (NHE1) and neuroprotective effects of NHE inhibitor in the gerbil hippocampal CA1 region induced by transient ischemia.
Topics: Amiloride; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Gerbillinae; Glial Fibrillary Acidic Protein; Hippocampus; Integrins; Ischemic Attack, Transient; Pyramidal Cells; Reperfusion; Sodium-Hydrogen Exchangers; Time Factors | 2008 |
Increased colonic sodium absorption in rats with chronic renal failure is partially mediated by AT1 receptor agonism.
Topics: Amiloride; Angiotensin II; Animals; Colon; Epithelial Sodium Channels; Intestinal Absorption; Kidney Failure, Chronic; Losartan; Male; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Sodium; Sodium-Hydrogen Exchangers; Water-Electrolyte Balance | 2008 |
Mutations alter the sodium versus proton use of a Bacillus clausii flagellar motor and confer dual ion use on Bacillus subtilis motors.
Topics: Amiloride; Bacillus; Bacillus subtilis; Bacterial Proteins; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Flagella; Hydrogen-Ion Concentration; Ions; Molecular Motor Proteins; Movement; Mutation; Protons; Sodium; Uncoupling Agents | 2008 |
Activation of Na+/H+ and K+/H+ exchange by calyculin A in Amphiuma tridactylum red blood cells: implications for the control of volume-induced ion flux activity.
Topics: Amiloride; Animals; Cell Size; Dose-Response Relationship, Drug; Enzyme Inhibitors; Erythrocytes; Marine Toxins; Osmotic Pressure; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Potassium; Potassium-Hydrogen Antiporters; Protein Kinases; Ruthenium; Sodium; Sodium-Hydrogen Exchangers; Time Factors; Urodela | 2008 |
Luminal hydrochloric acid stimulates rapid transepithelial ion fluxes in rodent esophageal stratified squamous epithelium.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adolescent; Aged; Amiloride; Animals; Autonomic Pathways; Bicarbonates; Buffers; Capsaicin; Cystic Fibrosis Transmembrane Conductance Regulator; Diffusion Chambers, Culture; Epithelium; Esophagus; Humans; Hydrochloric Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Ions; Male; Middle Aged; Neurons, Afferent; Parasympathetic Nervous System; Rats; Rats, Wistar; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers | 2008 |
The Na+/H+ exchanger modulates long-term potentiation in rat hippocampal slices.
Topics: Aging; Amiloride; Animals; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Neuroprotective Agents; Rats; Rats, Inbred BN; Rats, Inbred F344; Rats, Wistar; Sodium-Hydrogen Exchangers | 2009 |
Troglitazone induced cytosolic acidification via extracellular signal-response kinase activation and mitochondrial depolarization: complex I proton pumping regulates ammoniagenesis in proximal tubule-like LLC-PK1 cells.
Topics: Amiloride; Ammonia; Animals; Blotting, Western; Cell Line; Chromans; Cytochromes c; Cytosol; Electron Transport Complex I; Electron Transport Complex IV; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Hydrogen-Ion Concentration; Kidney Tubules, Proximal; Membrane Potential, Mitochondrial; Proton Pumps; Subcellular Fractions; Swine; Thiazolidinediones; Troglitazone | 2008 |
Identification of the Na+/H+ exchanger 1 in dorsal root ganglion and spinal cord: its possible role in inflammatory nociception.
Topics: Amiloride; Animals; Behavior, Animal; Blotting, Western; Dose-Response Relationship, Drug; Female; Ganglia, Spinal; Pain; Protein Isoforms; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium Channel Blockers; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Spinal Cord; Time Factors | 2009 |
Kaposi's sarcoma-associated herpesvirus utilizes an actin polymerization-dependent macropinocytic pathway to enter human dermal microvascular endothelial and human umbilical vein endothelial cells.
Topics: Acetophenones; Actins; Amiloride; Benzopyrans; Cells, Cultured; Chlorpromazine; Clathrin; Cytochalasin D; DNA, Viral; Endothelial Cells; Fibroblasts; Filipin; Gene Expression Regulation, Viral; Herpesvirus 8, Human; Humans; Hydrogen-Ion Concentration; Immediate-Early Proteins; Pinocytosis; rab GTP-Binding Proteins; Trans-Activators; Umbilical Veins; Virus Internalization | 2009 |
Amiloride derivatives induce apoptosis by depleting ER Ca(2+) stores in vascular endothelial cells.
Topics: Amiloride; Antigens, Differentiation; Apoptosis; Calcium; Cell Cycle Proteins; Diuretics; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Endothelial Cells; Enzyme Inhibitors; Guanidines; HeLa Cells; Humans; Hydrogen-Ion Concentration; Kinetics; Protein Phosphatase 1; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Sodium-Hydrogen Exchangers; Sulfones; Thapsigargin; Transcription Factor CHOP; Transcription, Genetic | 2009 |
Role of the sodium hydrogen exchanger in maitotoxin-induced cell death in cultured rat cortical neurons.
Topics: Acidosis; Amiloride; Animals; Antimetabolites, Antineoplastic; Calcium; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Female; Fluorometry; Marine Toxins; Methotrexate; Necrosis; Neurons; Neuroprotective Agents; Oxocins; Pregnancy; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Sodium-Hydrogen Exchangers | 2009 |
The Na+/H+ exchanger NHE1 is required for directional migration stimulated via PDGFR-alpha in the primary cilium.
Topics: Amiloride; Animals; Cation Transport Proteins; Cell Line; Cell Movement; Cilia; Interphase; Mice; NIH 3T3 Cells; Platelet-Derived Growth Factor; Receptor, Platelet-Derived Growth Factor alpha; RNA, Messenger; Signal Transduction; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Up-Regulation | 2009 |
Nhe1 is a luminal Na+/H+ exchanger in mouse choroid plexus and is targeted to the basolateral membrane in Ncbe/Nbcn2-null mice.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Bicarbonates; Cation Transport Proteins; Cell Membrane; Cell Polarity; Chloride-Bicarbonate Antiporters; Choroid Plexus; Fluoresceins; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Fluorescence; Protein Transport; Sodium; Sodium-Bicarbonate Symporters; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers | 2009 |
Protein transport in human cells mediated by covalently and noncovalently conjugated arginine-rich intracellular delivery peptides.
Topics: Amiloride; Arginine; beta-Cyclodextrins; Cell Line, Tumor; Cell Membrane; Cell Survival; Chlorates; Cytochalasin D; Drug Carriers; Fluorescence Resonance Energy Transfer; Green Fluorescent Proteins; Humans; Luminescent Proteins; Lysosomes; Mitochondria; Nocodazole; Oligopeptides; Peptides; Pinocytosis; Plasmids; Protein Transport; Recombinant Fusion Proteins; Red Fluorescent Protein; Temperature | 2009 |
pH regulating transporters in neurons from various chemosensitive brainstem regions in neonatal rats.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Ammonium Chloride; Animals; Animals, Newborn; Anti-Arrhythmia Agents; Brain Stem; Female; Guanidines; Hydrogen-Ion Concentration; Hypercapnia; Locus Coeruleus; Male; Membrane Transport Proteins; Neurons; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Sodium-Bicarbonate Symporters; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Solitary Nucleus; Sulfones | 2009 |
Bicarbonate transport by the human pancreatic ductal cell line HPAF.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenocarcinoma; Adenosine Triphosphate; Amiloride; Bicarbonates; Biological Transport; Bumetanide; Cell Line, Tumor; Chlorides; Cytophotometry; Fluoresceins; Humans; Hydrogen-Ion Concentration; Intracellular Space; Ion Transport; Membrane Potentials; Pancreatic Ducts; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2 | 2009 |
Ammonium-dependent sodium uptake in mitochondrion-rich cells of medaka (Oryzias latipes) larvae.
Topics: Amiloride; Ammonia; Animals; Biological Transport; Cation Transport Proteins; Dose-Response Relationship, Drug; Fish Proteins; Hydrogen-Ion Concentration; In Situ Hybridization; Ion-Selective Electrodes; Kinetics; Larva; Macrolides; Membrane Glycoproteins; Membrane Transport Modulators; Mitochondria; Oryzias; Quaternary Ammonium Compounds; Reverse Transcriptase Polymerase Chain Reaction; Rh-Hr Blood-Group System; RNA, Messenger; Sodium; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Water-Electrolyte Balance; Yolk Sac | 2010 |
Internalization of coxsackievirus A9 is mediated by {beta}2-microglobulin, dynamin, and Arf6 but not by caveolin-1 or clathrin.
Topics: ADP-Ribosylation Factor 6; ADP-Ribosylation Factors; Amiloride; beta 2-Microglobulin; Caveolae; Caveolin 1; Cell Line, Tumor; Clathrin; Dynamin II; Endocytosis; Enterovirus B, Human; Humans; Pinocytosis; RNA, Small Interfering; Virus Internalization | 2010 |
AE2 Cl-/HCO3- exchanger is required for normal cAMP-stimulated anion secretion in murine proximal colon.
Topics: 1-Methyl-3-isobutylxanthine; 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Acetazolamide; Amiloride; Animals; Animals, Newborn; Anion Transport Proteins; Anions; Antiporters; Bicarbonates; Bumetanide; Carbonic Anhydrase II; Carbonic Anhydrase III; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cation Transport Proteins; Cecum; Chlorides; Colforsin; Colon; Cyclic AMP; Electrophysiological Phenomena; Gene Expression; Ion Channels; Ion Pumps; Mice; Mice, Inbred Strains; Mice, Knockout; SLC4A Proteins; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2 | 2010 |
A role for Na+/H+ exchangers and intracellular pH in regulating vitamin C-driven electron transport across the plasma membrane.
Topics: Amiloride; Animals; Animals, Newborn; Ascorbic Acid; Astrocytes; Cell Line, Tumor; Cell Membrane; Cells, Cultured; Dehydroascorbic Acid; Electron Transport; Ferricyanides; Fluorometry; Humans; Hydrogen-Ion Concentration; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers | 2010 |
Inhibition of Na(+)/H(+) exchanger 1 by 5-(N-ethyl-N-isopropyl) amiloride reduces hypoxia-induced hepatocellular carcinoma invasion and motility.
Topics: Amiloride; Carcinoma, Hepatocellular; Cation Transport Proteins; Cell Hypoxia; Cell Movement; Extracellular Signal-Regulated MAP Kinases; Hep G2 Cells; Humans; Hydrogen-Ion Concentration; Liver Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Vascular Endothelial Growth Factor A | 2010 |
Ouabain stimulates Na-K-ATPase through a sodium/hydrogen exchanger-1 (NHE-1)-dependent mechanism in human kidney proximal tubule cells.
Topics: Adenosine Triphosphate; Amiloride; Animals; Blood Pressure; Cation Transport Proteins; Cell Line; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Hydrolysis; Kidney Tubules, Proximal; Opossums; Ouabain; Phosphorylation; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase; Time Factors; Transfection; Tyrosine | 2010 |
Sodium hydrogen exchanger as a mediator of hydrostatic edema-induced intestinal contractile dysfunction.
Topics: Amiloride; Analysis of Variance; Animals; Disease Models, Animal; Edema; Fluorescent Antibody Technique; Gastrointestinal Motility; Hydrostatic Pressure; Intestinal Diseases; Laparotomy; Male; Muscle Contraction; Muscle, Smooth; Polymerase Chain Reaction; Random Allocation; Rats; Reference Values; RNA, Messenger; Sensitivity and Specificity; Signal Transduction; Sodium-Hydrogen Exchangers; STAT3 Transcription Factor | 2011 |
A clathrin independent macropinocytosis-like entry mechanism used by bluetongue virus-1 during infection of BHK cells.
Topics: Amiloride; Animals; Bluetongue virus; Cell Line; Cholesterol; Clathrin; Cricetinae; Cytochalasin D; Endocytosis; Hydrogen-Ion Concentration; Membrane Fusion; Microscopy, Confocal; Microscopy, Fluorescence; Pinocytosis | 2010 |
Larvae of the midge Chironomus riparius possess two distinct mechanisms for ionoregulation in response to ion-poor conditions.
Topics: Amiloride; Animals; Body Water; Carbonic Anhydrase Inhibitors; Chironomidae; Chlorides; Hemolymph; Homeostasis; Hydrogen-Ion Concentration; Ion Transport; Larva; Methazolamide; Potassium; Protons; Sodium; Sodium Channel Blockers; Sodium Chloride; Time Factors; Water | 2010 |
Ammonia uptake in Manduca sexta midgut is mediated by an amiloride sensitive cation/proton exchanger: Transport studies and mRNA expression analysis of NHE7, 9, NHE8, and V-ATPase (subunit D).
Topics: Amiloride; Amino Acid Motifs; Amino Acid Sequence; Ammonia; Animals; Base Sequence; Biological Transport; Blotting, Northern; Cations; Cloning, Molecular; Gastrointestinal Tract; Gene Expression Profiling; Gene Expression Regulation; Humans; Manduca; Molecular Sequence Data; Phylogeny; Potassium; Protein Structure, Secondary; Protons; RNA, Messenger; Sodium-Hydrogen Exchangers; Vacuolar Proton-Translocating ATPases | 2010 |
Effect of metabolic acidosis on neonatal proximal tubule acidification.
Topics: Acidosis; Adaptation, Physiological; Amiloride; Animals; Animals, Newborn; Bicarbonates; Disease Models, Animal; Gene Expression Regulation; Hydrogen-Ion Concentration; Kidney Tubules, Proximal; Mice; Mice, Inbred C57BL; Microvilli; Rats; RNA, Messenger; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Time Factors | 2010 |
Cellular entry of ebola virus involves uptake by a macropinocytosis-like mechanism and subsequent trafficking through early and late endosomes.
Topics: Alcohol Oxidoreductases; Amiloride; Animals; Blotting, Western; Caveolae; Cells, Cultured; Chlorocebus aethiops; Clathrin; DNA-Binding Proteins; Ebolavirus; Endocytosis; Endosomes; Hemorrhagic Fever, Ebola; Humans; Kidney; Membrane Fusion; Membrane Microdomains; p21-Activated Kinases; Phosphorylation; Pinocytosis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Vero Cells; Virus Internalization; Virus Replication | 2010 |
Expression and modulation of Na(+) /H(+) exchanger 1 gene in hepatocellular carcinoma: A potential therapeutic target.
Topics: Adult; Aged; Aged, 80 and over; Amiloride; Animals; Apoptosis; Carcinoma, Hepatocellular; Cation Transport Proteins; Cell Proliferation; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; Genetic Therapy; Hep G2 Cells; Humans; Hydrogen-Ion Concentration; Immunohistochemistry; Liver Neoplasms; Male; Mice; Mice, Nude; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; RNA Interference; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Spectrometry, Fluorescence; Time Factors; Transfection; Tumor Burden; Up-Regulation; Xenograft Model Antitumor Assays | 2011 |
Decoupling of the catalytic and transport activities of complex I from Rhodothermus marinus by sodium/proton antiporter inhibitor.
Topics: Amiloride; Biological Transport; Catalysis; Electron Transport Complex I; Hydrogen; Hydrogen-Ion Concentration; Ion Transport; Membrane Potentials; Quinone Reductases; Rhodothermus; Sodium; Sodium-Hydrogen Exchangers; Valinomycin | 2011 |
[Comparison of mechanisms and cellular uptake of cell-penetrating peptide on different cell lines].
Topics: Adsorption; Amiloride; Cell Line, Tumor; Cell Membrane; Cell-Penetrating Peptides; Chloroquine; Chlorpromazine; Dose-Response Relationship, Drug; Exocytosis; Heparin; Humans; Proteoglycans; Temperature; Time Factors | 2010 |
Dissection of the influenza A virus endocytic routes reveals macropinocytosis as an alternative entry pathway.
Topics: Actomyosin; Amiloride; Cell Line, Tumor; Clathrin; Dynamins; Endocytosis; Fetal Blood; Gene Silencing; HeLa Cells; Host-Pathogen Interactions; Humans; Hydrazones; Influenza A virus; Pinocytosis; Receptor Protein-Tyrosine Kinases; RNA, Small Interfering; Virus Internalization | 2011 |
Plasma-accessible carbonic anhydrase at the tissue of a teleost fish may greatly enhance oxygen delivery: in vitro evidence in rainbow trout, Oncorhynchus mykiss.
Topics: Amiloride; Animals; Carbonic Anhydrases; Catecholamines; Erythrocytes; Hydrochloric Acid; Hydrogen-Ion Concentration; Isoproterenol; Models, Biological; Oncorhynchus mykiss; Organ Specificity; Oxygen; Sodium-Hydrogen Exchangers | 2011 |
Role of the spinal Na+/H+ exchanger in formalin-induced nociception.
Topics: Amiloride; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Female; Formaldehyde; Guanidines; Neurons; Pain; Pain Measurement; Pain Threshold; Pyrazoles; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sodium-Hydrogen Exchangers; Spinal Cord | 2011 |
Mechanism of ribonuclease A endocytosis: analogies to cell-penetrating peptides.
Topics: Amiloride; Animals; Cattle; Cell-Penetrating Peptides; Chlorpromazine; Cytochalasin D; Endocytosis; HeLa Cells; Humans; Hydrazones; Nystatin; Peptide Fragments; Ribonuclease, Pancreatic; tat Gene Products, Human Immunodeficiency Virus | 2011 |
Ammonia excretion via Rhcg1 facilitates Na⁺ uptake in larval zebrafish, Danio rerio, in acidic water.
Topics: Amiloride; Ammonia; Animals; Biological Transport; Buffers; Cation Transport Proteins; Gene Knockdown Techniques; Gills; Hydrogen-Ion Concentration; Kinetics; Larva; Macrolides; Proton-Translocating ATPases; Sodium; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Zebrafish; Zebrafish Proteins | 2011 |
The cardioprotective effect of brief acidic reperfusion after ischemia in perfused rat hearts is not mimicked by inhibition of the Na(+)/H(+) exchanger NHE1.
Topics: Acids; Amiloride; Animals; Apoptosis; Cells, Cultured; Hydrogen-Ion Concentration; Ischemic Postconditioning; Male; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Models, Biological; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocytes, Cardiac; Necrosis; Neuroprotective Agents; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers | 2011 |
Presynaptic regulation of quantal size: K+/H+ exchange stimulates vesicular glutamate transport.
Topics: Amiloride; Analysis of Variance; Animals; Animals, Newborn; Arthropod Proteins; Aspartic Acid; Biological Transport; Biophysical Phenomena; Brain; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cations; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Postsynaptic Potentials; Gluconates; Glutamic Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Ionophores; Membrane Potential, Mitochondrial; Monensin; Oligopeptides; Potassium; Presynaptic Terminals; Radionuclide Imaging; Rats; Rats, Wistar; Sodium Isotopes; Synapses; Synaptic Vesicles; Synaptosomes; Tritium; Vesicular Glutamate Transport Proteins | 2011 |
Bicarbonate, NBCe1, NHE, and carbonic anhydrase activity enhance lactate-H+ transport in bovine corneal endothelium.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Bicarbonates; Blotting, Western; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cattle; Cells, Cultured; Endothelium, Corneal; Fluorescent Antibody Technique, Indirect; Hydrogen-Ion Concentration; Lactic Acid; Monocarboxylic Acid Transporters; Niflumic Acid; Real-Time Polymerase Chain Reaction; Sodium-Bicarbonate Symporters; Sodium-Hydrogen Exchangers | 2011 |
The Ebola virus glycoprotein mediates entry via a non-classical dynamin-dependent macropinocytic pathway.
Topics: Actins; Amiloride; Animals; Cell Line; Chlorocebus aethiops; Dendritic Cells; Dynamin II; Ebolavirus; Humans; Hydrazones; Mice; Microscopy, Electron; Pinocytosis; Vero Cells; Vesiculovirus; Viral Envelope Proteins; Virus Internalization | 2011 |
Contribution of the amiloride-sensitive component and the Na+/H+ exchanger to renal responsiveness to vasoconstrictors.
Topics: Amiloride; Animals; Diuretics; Endothelium, Vascular; In Vitro Techniques; Kidney; Male; Rats; Rats, Wistar; Sodium Channel Blockers; Sodium-Hydrogen Exchangers; Vasoconstriction; Vasoconstrictor Agents | 2011 |
Ebola virus enters host cells by macropinocytosis and clathrin-mediated endocytosis.
Topics: Actins; Amiloride; Androstadienes; Animals; Bridged Bicyclo Compounds, Heterocyclic; Caveolin 1; Cell Line; Clathrin; Ebolavirus; Endocytosis; Epithelial Cells; Gene Silencing; Host-Pathogen Interactions; Humans; RNA, Small Interfering; Signal Transduction; Thiazolidines; Virus Internalization; Virus Replication; Wortmannin | 2011 |
Effect of aldosterone on the amplification of oncolytic vaccinia virus in human cancer lines.
Topics: Aldosterone; Amiloride; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Humans; Hydrocortisone; Hydrogen-Ion Concentration; Liver Neoplasms; Mineralocorticoid Receptor Antagonists; Neuroprotective Agents; Oncolytic Virotherapy; Rabbits; Spironolactone; Vaccinia virus; Virus Replication | 2011 |
The Na+/H+ exchanger NHE1, but not the Na+, HCO3(-) cotransporter NBCn1, regulates motility of MCF7 breast cancer cells expressing constitutively active ErbB2.
Topics: Amiloride; Benzamides; Breast Neoplasms; Cation Transport Proteins; Cell Adhesion; Cell Line, Tumor; Cell Movement; Chromones; Culture Media, Serum-Free; Cytoskeletal Proteins; Enzyme Inhibitors; Female; Humans; Hydrogen-Ion Concentration; Immunoblotting; Integrin beta1; Membrane Proteins; Microfilament Proteins; Morpholines; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptor, ErbB-2; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sodium-Bicarbonate Symporters; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Sulfonamides | 2012 |
Flow cytometry analysis reveals a decrease in intracellular sodium during sperm capacitation.
Topics: Amiloride; Animals; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Epithelial Sodium Channel Blockers; Flow Cytometry; Genistein; Male; Mice; Sodium; Sperm Capacitation; Spermatozoa | 2012 |
Performance of cell-penetrating peptide-linked polymers physically mixed with poorly membrane-permeable molecules on cell membranes.
Topics: Acetamides; Acrylates; Amiloride; Caco-2 Cells; Cell Membrane; Cell Membrane Permeability; Cell-Penetrating Peptides; Fluoresceins; Fluorescent Dyes; Humans; Microscopy, Confocal; Oligopeptides; Pinocytosis; Polyvinyls; Rhodamines; Time Factors | 2012 |
Plasma membrane-associated glycohydrolases activation by extracellular acidification due to proton exchangers.
Topics: Acetazolamide; Amiloride; beta-Galactosidase; beta-Glucosidase; beta-N-Acetylhexosaminidases; Cell Line, Tumor; Cell Membrane; Cells, Cultured; Egtazic Acid; Enzyme Activation; Fibroblasts; Glioma; Humans; Hydrogen-Ion Concentration; Neuroblastoma; Omeprazole; Protons | 2012 |
Anti-proliferative effect of atrial natriuretic peptide on colorectal cancer cells: evidence for an Akt-mediated cross-talk between NHE-1 activity and Wnt/β-catenin signaling.
Topics: Adenocarcinoma; Amiloride; Animals; Atrial Natriuretic Factor; beta Catenin; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Hydrogen-Ion Concentration; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Wnt Signaling Pathway | 2012 |
Comparative characterization of Na+ transport in Cyprinodon variegatus variegatus and Cyprinodon variegatus hubbsi: a model species complex for studying teleost invasion of freshwater.
Topics: Acclimatization; Amiloride; Animals; Cell Size; Chlorides; Epithelium; Fresh Water; Gills; Introduced Species; Ion Transport; Killifishes; Kinetics; Macrolides; Metolazone; Mitochondria; Models, Animal; Sodium; Species Specificity; Time Factors | 2012 |
Intracellular pH regulation in unstimulated Calliphora salivary glands is Na+ dependent and requires V-ATPase activity.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Alkalies; Amiloride; Amino Acid Sequence; Ammonium Chloride; Animals; Biological Transport; Chlorides; Diptera; Excitatory Amino Acid Transporter 1; Glutamic Acid; Hydrogen-Ion Concentration; Intracellular Space; Models, Biological; Molecular Sequence Data; Rest; Salivary Glands; Sodium; Solutions; Vacuolar Proton-Translocating ATPases | 2012 |
Uptake of ricinB-quantum dot nanoparticles by a macropinocytosis-like mechanism.
Topics: Actins; Amiloride; Cholesterol; Clathrin; Dynamins; HeLa Cells; Humans; Nanoparticles; Pinocytosis; Quantum Dots; rhoA GTP-Binding Protein; Ricin | 2012 |
Blockade of peripheral and spinal Na+/H+ exchanger increases formalin-induced long-lasting mechanical allodynia and hyperalgesia in rats.
Topics: Amiloride; Animals; Female; Hyperalgesia; Injections, Spinal; Pain Measurement; Peripheral Nerves; Physical Stimulation; Rats; Rats, Wistar; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Spinal Cord | 2012 |
Suppression of mammalian bone growth by membrane transport inhibitors.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Anion Transport Proteins; Antiporters; Bone and Bones; Bone Development; Cell Differentiation; Chondrocytes; Growth Plate; Membrane Transport Modulators; Metatarsal Bones; Organ Culture Techniques; Osteogenesis; Rats; Rats, Sprague-Dawley; SLC4A Proteins; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers | 2013 |
An inhibitor of Na(+)/H(+) exchanger (NHE), ethyl-isopropyl amiloride (EIPA), diminishes proliferation of MKN28 human gastric cancer cells by decreasing the cytosolic Cl(-) concentration via DIDS-sensitive pathways.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Antineoplastic Agents; Cell Proliferation; Chloride Channels; Chlorides; Cytosol; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Phosphoproteins; Sodium-Hydrogen Exchangers; Stomach Neoplasms; Structure-Activity Relationship; Tumor Cells, Cultured | 2012 |
Mechanisms of transepithelial ammonia excretion and luminal alkalinization in the gut of an intestinal air-breathing fish, Misgurnus anguilliacaudatus.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Air; Alkalies; Amiloride; Ammonia; Animals; Carbonic Anhydrase Inhibitors; Cypriniformes; Electrophysiological Phenomena; Epithelium; Ethoxzolamide; Intestinal Mucosa; Intestines; Membrane Fluidity; Models, Biological; Respiration; Serous Membrane; Sodium-Hydrogen Exchangers | 2013 |
Na(+)-H+ exchange inhibition attenuates ischemic injury in rat random pattern skin flap: the role of mitochondrial ATP-sensitive potassium channels.
Topics: Amiloride; Animals; Dermatologic Surgical Procedures; Diazoxide; Glyburide; Ion Channel Gating; Ischemia; KATP Channels; Male; Mitochondria; Postoperative Complications; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Surgical Flaps; Tissue Survival | 2013 |
A. actinomycetemcomitans LPS enhances foam cell formation induced by LDL.
Topics: Acid Sensing Ion Channel Blockers; Aggregatibacter actinomycetemcomitans; Amiloride; Animals; Cell Line; Drug Synergism; Foam Cells; Lipopolysaccharides; Lipoproteins, LDL; Macrophages; Mice; Microtubules; Nocodazole; Periodontitis; Pinocytosis; Receptors, LDL; Sodium-Hydrogen Exchangers; Tubulin Modulators | 2013 |
Oncogenic activation of Pak1-dependent pathway of macropinocytosis determines BCG entry into bladder cancer cells.
Topics: Amiloride; BCG Vaccine; cdc42 GTP-Binding Protein; Cell Line, Tumor; Clathrin; Cytochalasin D; Dynamins; Humans; p21-Activated Kinases; Phosphatidylinositol 3-Kinases; Pinocytosis; PTEN Phosphohydrolase; rac1 GTP-Binding Protein; ras Proteins; Staurosporine; Urinary Bladder Neoplasms | 2013 |
Proton-facilitated ammonia excretion by ionocytes of medaka (Oryzias latipes) acclimated to seawater.
Topics: Acclimatization; Amiloride; Ammonia; Animals; Buffers; Electrodes; Epithelial Sodium Channel Blockers; Glycine; Glycoproteins; Immunohistochemistry; In Situ Hybridization; Larva; Oryzias; Protons; Real-Time Polymerase Chain Reaction; RNA; Seawater; Skin; Sodium-Hydrogen Exchangers; Yolk Sac | 2013 |
Effect of NSAIDs on Na⁺/H⁺ exchanger activity in rat colonic crypts.
Topics: Amiloride; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colon; Epithelial Sodium Channel Blockers; Gene Expression Regulation; Guanidines; Humans; Hydrogen-Ion Concentration; Indomethacin; Ion Transport; Male; Pyrazoles; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers | 2013 |
The Na⁺/H⁺ exchanger isoform 3 is required for active paracellular and transcellular Ca²⁺ transport across murine cecum.
Topics: Amiloride; Animals; Calcium; Calcium Channels; Cecum; Female; Gene Expression Regulation; Intestinal Absorption; Intestinal Mucosa; Ion Transport; Male; Membrane Potentials; Membrane Transport Modulators; Mice; Mice, Knockout; Patch-Clamp Techniques; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Ruthenium Red; Sodium; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; TRPV Cation Channels; Water | 2013 |
SLC4A11 is an EIPA-sensitive Na(+) permeable pHi regulator.
Topics: Amiloride; Amino Acid Sequence; Ammonium Chloride; Animals; Anion Transport Proteins; Antiporters; Cell Membrane Permeability; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Epithelial Sodium Channel Blockers; HEK293 Cells; Humans; Hydrogen-Ion Concentration; Ion Transport; Molecular Sequence Data; Sodium; Sodium Hydroxide; Time Factors; Transfection | 2013 |
A presynaptic ENaC channel drives homeostatic plasticity.
Topics: Amiloride; Animals; Animals, Genetically Modified; Calcium; Central Nervous System; Dose-Response Relationship, Drug; Drosophila melanogaster; Drosophila Proteins; Epithelial Sodium Channels; Excitatory Postsynaptic Potentials; Homeostasis; Larva; Mutation; Nerve Tissue Proteins; Neuromuscular Junction; Neuronal Plasticity; Neuroprotective Agents; Nicotinic Antagonists; Patch-Clamp Techniques; Polyamines; Presynaptic Terminals; Sodium Channels | 2013 |
Elevated carbon dioxide upregulates NBCn1 Na+/HCO3(-) cotransporter in human embryonic kidney cells.
Topics: Amiloride; Bicarbonates; Carbon Dioxide; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Hydrogen-Ion Concentration; Sodium-Bicarbonate Symporters; Time Factors; Up-Regulation | 2013 |
Sodium-hydrogen exchanger inhibitory potential of Malus domestica, Musa × paradisiaca, Daucus carota, and Symphytum officinale.
Topics: Amiloride; Blood Platelets; Comfrey; Daucus carota; Humans; In Vitro Techniques; Inhibitory Concentration 50; Malus; Musa; Plant Extracts; Sodium-Hydrogen Exchangers | 2014 |
BI-1 enhances Fas-induced cell death through a Na+/H+-associated mechanism.
Topics: Amiloride; Antibodies; Apoptosis; Apoptosis Regulatory Proteins; Calcium; Caspase 3; Cell Line, Tumor; Cytosol; fas Receptor; Humans; Hydrogen-Ion Concentration; Membrane Proteins; RNA Interference; RNA, Small Interfering; Sodium-Hydrogen Exchangers | 2014 |
Na+/H+ and Na+/NH+4 activities of zebrafish NHE3b expressed in Xenopus oocytes.
Topics: Acid Sensing Ion Channel Blockers; Amiloride; Ammonium Compounds; Animals; Electrophysiological Phenomena; Fresh Water; Gene Expression Regulation; Hydrogen-Ion Concentration; Microelectrodes; Oocytes; Sodium; Sodium-Hydrogen Exchangers; Thermodynamics; Xenopus; Zebrafish | 2014 |
Characterization of the Na/HCO3(-) cotransport in human neutrophils.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Amiloride; Ammonium Chloride; Benzamides; Bicarbonates; Cytochalasin B; HEK293 Cells; Humans; Hydrogen-Ion Concentration; Ion Transport; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Protein Isoforms; RNA, Messenger; Sodium-Bicarbonate Symporters; Sodium-Hydrogen Exchangers; Sulfonamides | 2014 |
Acid-sensing ion channels are involved in epithelial Na+ uptake in the rainbow trout Oncorhynchus mykiss.
Topics: Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Amiloride; Amino Acid Sequence; Animals; Antibodies; Biological Transport, Active; Cloning, Molecular; Diminazene; Gills; Indoles; Oncorhynchus mykiss; Sequence Alignment; Sodium; Sodium-Potassium-Exchanging ATPase; Trypanocidal Agents | 2014 |
Repeated administration of inhibitors for ion pumps reduce markedly tumor growth in vivo.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Cell Division; Cell Proliferation; Hydrogen-Ion Concentration; Ion Pumps; Mastocytoma; Mice; Mice, Inbred DBA; Peritoneal Neoplasms; Tumor Burden; Tumor Microenvironment | 2014 |
An in vitro investigation of gastrointestinal Na(+) uptake mechanisms in freshwater rainbow trout.
Topics: Amiloride; Animals; Biological Transport; Fresh Water; Furosemide; Gastrointestinal Tract; Hydrochlorothiazide; In Vitro Techniques; Kinetics; Macrolides; Models, Biological; Oncorhynchus mykiss; Osmolar Concentration; Osmoregulation; Regression Analysis; Sodium Radioisotopes | 2014 |
Transport pathways of solid lipid nanoparticles across Madin-Darby canine kidney epithelial cell monolayer.
Topics: Amiloride; Animals; Biological Transport; Cell Line; Dogs; Endocytosis; Exocytosis; Madin Darby Canine Kidney Cells; Nanoparticles | 2014 |
Energy independent uptake and release of polystyrene nanoparticles in primary mammalian cell cultures.
Topics: Amiloride; Animals; Biological Transport; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Caveolin 1; Cell Membrane; Cells, Cultured; Colon; Drug Delivery Systems; Endocytosis; Epithelial Cells; Female; Fibroblasts; Humans; Hydrazones; Microscopy, Confocal; Nanoparticles; Neoplasms; Oviducts; Particle Size; Polystyrenes; Primary Cell Culture; Spectrometry, Fluorescence; Sucrose; Thiazolidines | 2015 |
Sequence-dependent internalization of aggregating peptides.
Topics: Actin Cytoskeleton; Amiloride; Amino Acid Sequence; Cytochalasin D; DNA-Binding Proteins; Endocytosis; Endosomes; Heat Shock Transcription Factors; HEK293 Cells; HSP70 Heat-Shock Proteins; Humans; Hydrazones; Hydrogen-Ion Concentration; Kinetics; Lovastatin; Lysosomes; Molecular Sequence Data; Peptides; Protein Aggregates; Protein Binding; Protein Folding; Protein Transport; Proteolysis; Structure-Activity Relationship; Transcription Factors | 2015 |
A crosstalk between Na⁺ channels, Na⁺/K⁺ pump and mitochondrial Na⁺ transporters controls glucose-dependent cytosolic and mitochondrial Na⁺ signals.
Topics: Amiloride; Animals; Cells, Cultured; Cytosol; Female; Glucose; Insulin-Secreting Cells; Mice; Mice, Inbred DBA; Mitochondria; Ouabain; RNA Interference; RNA, Small Interfering; Signal Transduction; Sodium; Sodium Channels; Sodium-Calcium Exchanger; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase; Tetrodotoxin | 2015 |
The role of acid-sensing ion channels in epithelial Na+ uptake in adult zebrafish (Danio rerio).
Topics: Acclimatization; Acid Sensing Ion Channels; Amiloride; Animals; Biological Transport, Active; Epithelium; Gene Expression Profiling; Gills; Indoles; Sodium; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase; Vacuolar Proton-Translocating ATPases; Water; Zebrafish; Zebrafish Proteins | 2015 |
Experimental Study of the Effects of EIPA, Losartan, and BQ-123 on Electrophysiological Changes Induced by Myocardial Stretch.
Topics: Amiloride; Angiotensin II Type 1 Receptor Blockers; Animals; Endothelin Receptor Antagonists; Epithelial Sodium Channel Blockers; Heart; Losartan; Myocardium; Peptides, Cyclic; Rabbits; Sodium-Hydrogen Exchangers; Stress, Physiological; Ventricular Fibrillation | 2015 |
Cloning and characterization of Na(+)/H(+) Exchanger isoforms NHE2 and NHE3 from the gill of Pacific dogfish Squalus suckleyi.
Topics: Amiloride; Animals; Biological Transport, Active; Cell Line; Cloning, Molecular; Cricetinae; Dogfish; Epithelial Sodium Channel Blockers; Fish Proteins; Gills; Inhibitory Concentration 50; Protein Isoforms; Sodium-Hydrogen Exchangers | 2015 |
Inhibition of the Na+/H+ antiporter induces cell death in TF-1 erythroleukemia cells stimulated by the stem cell factor.
Topics: Amiloride; Apoptosis; Autophagy; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Separation; Cell Survival; Fluorescent Dyes; Gene Expression Regulation, Leukemic; Humans; Hydrogen-Ion Concentration; Leukemia; Leukemia, Erythroblastic, Acute; Membrane Potentials; Mitochondrial Membranes; Proto-Oncogene Proteins c-bcl-2; Sodium-Hydrogen Exchangers; Stem Cell Factor | 2015 |
Taurine Boosts Cellular Uptake of Small D-Peptides for Enzyme-Instructed Intracellular Molecular Self-Assembly.
Topics: 4-Chloro-7-nitrobenzofurazan; Amiloride; Amino Acids; Buffers; Cell-Penetrating Peptides; Endocytosis; Esters; Fluorescence; HeLa Cells; Humans; Microscopy, Electron, Transmission; Taurine | 2015 |
Acidosis and 5-(N-ethyl-N-isopropyl)amiloride (EIPA) Attenuate Zinc/Kainate Toxicity in Cultured Cerebellar Granule Neurons.
Topics: Acidosis; Amiloride; Animals; Calcium; Cations, Divalent; Cell Death; Cells, Cultured; Cerebellum; Cytoplasmic Granules; Drug Interactions; Kainic Acid; Neurons; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Sodium-Hydrogen Exchangers; Zinc | 2015 |
A novel type bacterial flagellar motor that can use divalent cations as a coupling ion.
Topics: Amiloride; Amino Acid Sequence; Bacterial Proteins; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cations, Divalent; Cations, Monovalent; Flagella; Intracellular Space; Magnesium; Molecular Motor Proteins; Movement; Mutation; Paenibacillus; Phylogeny; Protein Subunits | 2016 |
Role of Rho kinase and Na+/H+ exchange in hypoxia-induced pulmonary arterial smooth muscle cell proliferation and migration.
Topics: Amides; Amiloride; Animals; Cation Transport Proteins; Cell Hypoxia; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Enzyme Activation; Hydrogen-Ion Concentration; Hypertension, Pulmonary; Hypoxia; Male; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Protein Kinase Inhibitors; Pulmonary Artery; Pyridines; Rats, Wistar; rho-Associated Kinases; Signal Transduction; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Vascular Remodeling | 2016 |
The Pro-inflammatory Cytokine Interleukin-6 Regulates Nanoparticle Transport Across Model Follicle-Associated Epithelium Cells.
Topics: Amiloride; B-Lymphocytes; Caco-2 Cells; Dose-Response Relationship, Drug; Epithelial Cells; Hair Follicle; Humans; Immunoglobulin A; Interleukin-6; Intestinal Mucosa; Mannitol; Nanoparticles; Permeability; Tumor Necrosis Factor-alpha | 2016 |
A Novel Role of Dickkopf-Related Protein 3 in Macropinocytosis in Human Bladder Cancer T24 Cells.
Topics: Adaptor Proteins, Signal Transducing; Adenine; Amiloride; Autophagy; Cell Line, Tumor; Cell Proliferation; Chemokines; Epithelial Cells; G1 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Intercellular Signaling Peptides and Proteins; Lysosomal Membrane Proteins; MAP Kinase Kinase 4; MicroRNAs; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Pinocytosis; rab5 GTP-Binding Proteins; rac1 GTP-Binding Protein; RNA, Small Interfering; Signal Transduction; Urinary Bladder | 2016 |
A new HDAC inhibitor cinnamoylphenazine shows antitumor activity in association with intensive macropinocytosis.
Topics: A549 Cells; Amiloride; Animals; Blotting, Western; Cell Line, Tumor; Cinnamates; Colonic Neoplasms; Epithelial Sodium Channel Blockers; Female; HCT116 Cells; Histone Deacetylase Inhibitors; HT29 Cells; Humans; Mice, Inbred BALB C; Mice, Nude; Microscopy, Confocal; Pancreatic Neoplasms; Phenazines; Pinocytosis; Xenograft Model Antitumor Assays | 2017 |
Measles Virus Enters Breast and Colon Cancer Cell Lines through a PVRL4-Mediated Macropinocytosis Pathway.
Topics: Actins; Amiloride; Animals; Breast Neoplasms; Cell Adhesion Molecules; Cell Line; Chlorocebus aethiops; Colonic Neoplasms; Epithelial Cells; Female; Humans; MCF-7 Cells; Measles virus; Oncolytic Viruses; p21-Activated Kinases; Pinocytosis; RNA, Small Interfering; Vero Cells; Virus Internalization | 2017 |
Na+/H+ Exchanger Regulates Amino Acid-Mediated Autophagy in Intestinal Epithelial Cells.
Topics: Alanine; Amiloride; Amino Acids; Animals; Autophagy; Autophagy-Related Proteins; Cell Line; Epithelial Cells; Intestinal Mucosa; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Microtubule-Associated Proteins; Proline; Rats; Real-Time Polymerase Chain Reaction; Sodium-Hydrogen Exchangers; Up-Regulation | 2017 |
Pharmacological evidence that DAPI inhibits NHE2 in Fundulus heteroclitus acclimated to freshwater.
Topics: Acclimatization; Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Amiloride; Animals; Aquaculture; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Enzyme Inhibitors; Ethoxzolamide; Fish Proteins; Fresh Water; Fundulidae; Indoles; Macrolides; Membrane Transport Modulators; Osmolar Concentration; Osmoregulation; Protein Isoforms; Proton-Translocating ATPases; Reproducibility of Results; Sodium-Hydrogen Exchangers | 2018 |
Vps34-mediated macropinocytosis in Tuberous Sclerosis Complex 2-deficient cells supports tumorigenesis.
Topics: Amiloride; Animals; Autophagy; Autophagy-Related Protein 5; Carcinogenesis; Cell Line; Cell Proliferation; Class III Phosphatidylinositol 3-Kinases; Dextrans; Down-Regulation; Mice; Mice, Inbred NOD; Mice, SCID; Pinocytosis; Protein Kinase Inhibitors; Tuberous Sclerosis; Tuberous Sclerosis Complex 2 Protein; Up-Regulation | 2018 |
Macropinocytosis dependent entry of Chikungunya virus into human muscle cells.
Topics: Amiloride; Animals; Cadaverine; Cell Line; Cell Survival; Chikungunya Fever; Chikungunya virus; Clathrin; Endocytosis; Filipin; Gene Knockdown Techniques; Humans; Hydrazones; Kinetics; Muscles; Pinocytosis; Rhabdomyosarcoma; RNA, Small Interfering; Sorting Nexins; Viral Load; Viral Plaque Assay; Virus Internalization | 2019 |
Intracellular pH regulation in mantle epithelial cells of the Pacific oyster, Crassostrea gigas.
Topics: Acetazolamide; Amiloride; Animals; Calcification, Physiologic; Carbonic Anhydrase Inhibitors; Crassostrea; Cytophotometry; Epithelial Cells; Hydrogen-Ion Concentration; Ion Transport; Sodium Channel Blockers; Sodium-Hydrogen Exchangers | 2020 |
Ethyl isopropyl amiloride decreases oxidative phosphorylation and increases mitochondrial fusion in clonal untransformed and cancer cells.
Topics: Amiloride; Cell Line; Cell Line, Tumor; Clone Cells; Epithelial Cells; Epithelial Sodium Channel Blockers; Gene Expression; Glycolysis; Humans; Hydrogen-Ion Concentration; Lactic Acid; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Dynamics; Oxidative Phosphorylation; Oxygen Consumption; Phosphofructokinase-1; Pyruvic Acid; Sodium-Hydrogen Exchanger 1 | 2021 |
Therapeutic efficacy of proton transport inhibitors alone or in combination with cisplatin in triple negative and hormone sensitive breast cancer models.
Topics: Amiloride; Animals; Antineoplastic Combined Chemotherapy Protocols; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Cell Proliferation; Cisplatin; Esomeprazole; Female; Humans; Hydrogen-Ion Concentration; Mice, Inbred BALB C; Proton Pump Inhibitors; Sodium-Hydrogen Exchanger 1; Triple Negative Breast Neoplasms; Tumor-Associated Macrophages; Vacuolar Proton-Translocating ATPases | 2022 |