Page last updated: 2024-08-17

ethylene oxide and valine

ethylene oxide has been researched along with valine in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19903 (10.71)18.7374
1990's13 (46.43)18.2507
2000's6 (21.43)29.6817
2010's4 (14.29)24.3611
2020's2 (7.14)2.80

Authors

AuthorsStudies
Denk, B; Ehrenberg, L; Filser, JG; Kessler, W; Törnqvist, M1
Fennell, TR; MacNeela, JP; Swenberg, JA; Turner, MJ; Walker, VE1
Attewell, R; Hagmar, L; Lindén, K; Osterman-Golkar, S; Törnqvist, M; Welinder, H1
Törnqvist, M2
Almberg, JG; Bergmark, EN; Nilsson, S; Osterman-Golkar, SM; Törnqvist, MA1
Ehrenberg, L; Granath, F; Gustafsson, B; Harms-Ringdahl, M; Kautiainen, A; Törnqvist, M1
Bailey, E; Brooks, AG; Dollery, CT; Farmer, PB; Passingham, BJ; Sleightholm, MA; Yates, DW1
Boogaard, PJ; Caubo, ME; Darroudi, F; Natarajan, AT; Tates, AD; van Sittert, NJ1
Fennell, TR; MacNeela, JP; Swenberg, JA; Upton, PB; Walker, VE1
Beulink, GD; van der Waal, H; van Sittert, NJ; van Vliet, EW1
Bolt, HM1
Angerer, J; Bader, M; Krämer, A1
Angerer, J; Hallier, E; Krämer, A; Müller, M1
Bono, R; Giachino, O; Meineri, V; Pignata, C; Saglia, U; Scursatone, E; Vincenti, M1
Boogaard, PJ; Rocchi, PS; van Sittert, NJ1
Cho, MH; Ranasinghe, A; Scheller, N; Skopek, TR; Swenberg, JA; Upton, PB; Vergnes, JS; Walker, VE; Wu, KY1
Balkenhol, H; Bolt, HM; Dommermuth, A; Lewalter, J; Selinski, S; Thier, R1
Angerer, J; Broding, HC; Drexler, H; Schettgen, T1
Chen, YL; Chiang, SY; Hsieh, CL; Huang, TH; Kuo, HW; Tseng, YS; Wu, KY1
Ali, MY; Hurst, HE1
Ahn, HS; Shin, HS1
Bader, M; Frey, G; Nasterlack, M; Will, W1
Boogaard, PJ; Urbanus, JH; van Puijvelde, MJ1
Hays, SM; Kirman, CR1
Dabrowská, L; Dušková, Š; Hanzlíková, I; Hejl, K; Linhart, I; Mráz, J1
Buchanan, S; Friedman, L; Szwiec, E1
Bus, JS; Hays, SM; Kirman, CR; Lewis, RC; Li, AA; Sheehan, PJ1

Reviews

3 review(s) available for ethylene oxide and valine

ArticleYear
Quantification of endogenous carcinogens. The ethylene oxide paradox.
    Biochemical pharmacology, 1996, Jul-12, Volume: 52, Issue:1

    Topics: Animals; Carcinogens; DNA; Ethylene Oxide; Guanine; Hemoglobins; Humans; Valine

1996
Ethylene oxide as a biological reactive intermediate of endogenous origin.
    Advances in experimental medicine and biology, 1996, Volume: 387

    Topics: Animals; Ethylene Oxide; Hemoglobins; Humans; Neoplasms; Reactive Oxygen Species; Valine

1996
Ethylene oxide review: characterization of total exposure via endogenous and exogenous pathways and their implications to risk assessment and risk management.
    Journal of toxicology and environmental health. Part B, Critical reviews, 2021, 01-02, Volume: 24, Issue:1

    Topics: Animals; Environmental Exposure; Environmental Monitoring; Ethylene Oxide; Female; Humans; Male; Risk Assessment; Risk Factors; Risk Management; Valine

2021

Trials

1 trial(s) available for ethylene oxide and valine

ArticleYear
Ambient and biochemical effect monitoring of workers exposed to ethylene oxide.
    International archives of occupational and environmental health, 1998, Volume: 71, Issue:1

    Topics: Air Pollution, Indoor; Environment, Controlled; Environmental Monitoring; Ethylene Oxide; Gas Chromatography-Mass Spectrometry; Humans; Male; Occupational Exposure; Reproducibility of Results; Sensitivity and Specificity; Valine

1998

Other Studies

24 other study(ies) available for ethylene oxide and valine

ArticleYear
Pharmacokinetics of ethylene in man; body burden with ethylene oxide and hydroxyethylation of hemoglobin due to endogenous and environmental ethylene.
    Archives of toxicology, 1992, Volume: 66, Issue:3

    Topics: Adult; Aged; Alkylation; Body Burden; Environmental Exposure; Ethylene Oxide; Ethylenes; Female; Hemoglobins; Humans; Hydroxylation; Male; Middle Aged; Valine

1992
Molecular dosimetry of ethylene oxide: formation and persistence of N-(2-hydroxyethyl)valine in hemoglobin following repeated exposures of rats and mice.
    Cancer research, 1992, Aug-15, Volume: 52, Issue:16

    Topics: Administration, Inhalation; Animals; Dose-Response Relationship, Drug; Drug Administration Schedule; Erythrocyte Aging; Ethylene Oxide; Formamides; Globins; Hemoglobin A; Male; Mice; Mice, Inbred C3H; Rats; Rats, Inbred F344; Valine

1992
An epidemiological study of cancer risk among workers exposed to ethylene oxide using hemoglobin adducts to validate environmental exposure assessments.
    International archives of occupational and environmental health, 1991, Volume: 63, Issue:4

    Topics: Adult; Aged; Cohort Studies; Environmental Monitoring; Epidemiological Monitoring; Ethylene Oxide; Female; Hemoglobins; Humans; Male; Middle Aged; Morbidity; Neoplasms; Occupational Diseases; Occupational Exposure; Risk Factors; Valine

1991
Formation of reactive species that lead to hemoglobin adducts during storage of blood samples.
    Carcinogenesis, 1990, Volume: 11, Issue:1

    Topics: Alkylation; Blood Preservation; Cell Separation; Erythrocytes; Ethylene Oxide; Freeze Drying; Globins; Hemoglobins; Hemolysis; Histidine; Humans; Valine

1990
Ethylene oxide doses in ethene-exposed fruit store workers.
    Scandinavian journal of work, environment & health, 1989, Volume: 15, Issue:6

    Topics: Air Pollutants, Occupational; Ethylene Oxide; Ethylenes; Food Handling; Fruit; Hemoglobins; Humans; Valine

1989
Unsaturated lipids and intestinal bacteria as sources of endogenous production of ethene and ethylene oxide.
    Carcinogenesis, 1989, Volume: 10, Issue:1

    Topics: Animals; Dietary Fats; Ethylene Oxide; Ethylenes; Fatty Acids, Unsaturated; Intestinal Mucosa; Intestines; Lipid Peroxides; Male; Mice; Mice, Inbred CBA; Valine

1989
Hydroxyethylvaline adduct formation in haemoglobin as a biological monitor of cigarette smoke intake.
    Archives of toxicology, 1988, Volume: 62, Issue:4

    Topics: Biomarkers; Cotinine; Ethylene Oxide; Hemoglobins; Humans; Nicotiana; Plants, Toxic; Smoke; Valine

1988
Biological effect monitoring in industrial workers following incidental exposure to high concentrations of ethylene oxide.
    Mutation research, 1995, Volume: 329, Issue:1

    Topics: Accidents, Occupational; Adult; Case-Control Studies; Chemical Industry; DNA Adducts; Environmental Monitoring; Erythrocytes; Ethylene Oxide; Hemoglobins; Humans; Hypoxanthine Phosphoribosyltransferase; Lymphocytes; Micronuclei, Chromosome-Defective; Middle Aged; Mutation; Netherlands; Occupational Exposure; Sister Chromatid Exchange; Valine

1995
Molecular dosimetry of DNA and hemoglobin adducts in mice and rats exposed to ethylene oxide.
    Environmental health perspectives, 1993, Volume: 99

    Topics: Animals; DNA; DNA Damage; Dose-Response Relationship, Drug; Ethylene Oxide; Guanine; Hemoglobins; Male; Mice; Rats; Rats, Inbred F344; Time Factors; Valine

1993
Monitoring occupational exposure to ethylene oxide by the determination of hemoglobin adducts.
    Environmental health perspectives, 1993, Volume: 99

    Topics: Chemical Industry; Environmental Monitoring; Ethylene Oxide; Hemoglobins; Humans; Occupational Exposure; Valine

1993
Ethylene oxide-protein adduct formation in humans: influence of glutathione-S-transferase polymorphisms.
    International archives of occupational and environmental health, 1998, Volume: 71, Issue:7

    Topics: Case-Control Studies; DNA Adducts; Environmental Exposure; Ethylene Oxide; Female; Genotype; Glutathione Transferase; Humans; Male; Polymerase Chain Reaction; Polymorphism, Genetic; Smoking; Statistics, Nonparametric; Substrate Specificity; Surveys and Questionnaires; Valine

1998
Formation of N-(2-hydroxyethyl)valine due to exposure to ethylene oxide via tobacco smoke: A risk factor for onset of cancer.
    Environmental research, 1999, Volume: 81, Issue:1

    Topics: Adolescent; Adult; Biomarkers; Carcinogens; Cotinine; Ethylene Oxide; Female; Gas Chromatography-Mass Spectrometry; Hemoglobins; Humans; Male; Risk Factors; Smoking; Surveys and Questionnaires; Tobacco Smoke Pollution; Urban Population; Valine

1999
Biomonitoring of exposure to ethylene oxide and propylene oxide by determination of hemoglobin adducts: correlations between airborne exposure and adduct levels.
    International archives of occupational and environmental health, 1999, Volume: 72, Issue:3

    Topics: Air Pollutants, Occupational; Biomarkers; Carcinogens; Chromatography, Gas; Environmental Monitoring; Epoxy Compounds; Ethylene Oxide; Gas Chromatography-Mass Spectrometry; Hemoglobins; Humans; Male; Occupational Exposure; Valine

1999
Biomarkers of exposure and effect as indicators of potential carcinogenic risk arising from in vivo metabolism of ethylene to ethylene oxide.
    Carcinogenesis, 2000, Volume: 21, Issue:9

    Topics: Animals; Biomarkers; Biotransformation; Carcinogens; DNA; DNA Damage; Dose-Response Relationship, Drug; Ethylene Oxide; Ethylenes; Guanine; Hemoglobins; Hypoxanthine Phosphoribosyltransferase; Inhalation Exposure; Male; Mice; Mice, Inbred Strains; Mutation; Rats; Rats, Inbred F344; T-Lymphocytes; Valine

2000
Influence of polymorphisms of the human glutathione transferases and cytochrome P450 2E1 enzyme on the metabolism and toxicity of ethylene oxide and acrylonitrile.
    Mutation research, 2001, Oct-01, Volume: 482, Issue:1-2

    Topics: Acrylonitrile; Carcinogens; Cytochrome P-450 CYP2E1; DNA Adducts; Ethylene Oxide; Glutathione S-Transferase pi; Glutathione Transferase; Hemoglobins; Humans; Isoenzymes; Occupational Exposure; Polymorphism, Genetic; Valine

2001
Hemoglobin adducts of ethylene oxide, propylene oxide, acrylonitrile and acrylamide-biomarkers in occupational and environmental medicine.
    Toxicology letters, 2002, Aug-05, Volume: 134, Issue:1-3

    Topics: Acrylamide; Acrylonitrile; Adult; Biomarkers; Diet; Epoxy Compounds; Ethylene Oxide; Gas Chromatography-Mass Spectrometry; Hemoglobins; Humans; Middle Aged; Occupational Exposure; Smoking; Valine

2002
Formation of N-(2-hydroxyethyl)valine in human hemoglobin-effect of lifestyle factors.
    Mutation research, 2004, Apr-11, Volume: 559, Issue:1-2

    Topics: Adult; Age Factors; Alcohol Drinking; Analysis of Variance; Biomarkers; Ethylene Oxide; Ethylenes; Female; Gas Chromatography-Mass Spectrometry; Hemoglobins; Humans; Life Style; Male; Risk Factors; Sex Factors; Smoking; Taiwan; Tea; Valine

2004
Analyses of (1-chloroethenyl)oxirane headspace and hemoglobin N-valine adducts in erythrocytes indicate selective detoxification of (1-chloroethenyl)oxirane enantiomers.
    Chemico-biological interactions, 2007, Mar-20, Volume: 166, Issue:1-3

    Topics: Animals; Chromatography, Gas; Erythrocytes; Ethylene Oxide; Glutathione; Glutathione Transferase; Hemoglobins; Inactivation, Metabolic; Kinetics; Mass Spectrometry; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Stereoisomerism; Valine; Volatilization

2007
Determination of ethylene oxide-hemoglobin adduct by silylation and gas chromatography-electron impact-mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2006, Nov-07, Volume: 843, Issue:2

    Topics: Biomarkers; Environmental Exposure; Ethylene Oxide; Gas Chromatography-Mass Spectrometry; Hemoglobins; Humans; Reproducibility of Results; Trimethylsilyl Compounds; Valine

2006
Analysis of protein adducts as biomarkers of short-term exposure to ethylene oxide and results of follow-up biomonitoring.
    Arhiv za higijenu rada i toksikologiju, 2012, Jun-01, Volume: 63, Issue:2

    Topics: Accidents, Occupational; Biomarkers; Carcinogens; Chemical Industry; Cotinine; Ethylene Oxide; Humans; Male; Occupational Exposure; Smoking; Valine

2012
Biological monitoring to assess dermal exposure to ethylene oxide vapours during an incidental release.
    Toxicology letters, 2014, Dec-15, Volume: 231, Issue:3

    Topics: Adult; Chemical Hazard Release; Environmental Monitoring; Ethylene Oxide; Humans; Male; Models, Biological; Netherlands; Occupational Exposure; Skin Absorption; Valine

2014
Derivation of endogenous equivalent values to support risk assessment and risk management decisions for an endogenous carcinogen: Ethylene oxide.
    Regulatory toxicology and pharmacology : RTP, 2017, Volume: 91

    Topics: Animals; Biomarkers; Carcinogens; Dose-Response Relationship, Drug; Ethylene Oxide; Humans; Occupational Exposure; Risk Assessment; Risk Management; Valine

2017
N-(2-Hydroxyethyl)-L-valyl-L-leucine in rat urine as a hydrolytic cleavage product of ethylene oxide adduct with globin.
    Archives of toxicology, 2019, Volume: 93, Issue:3

    Topics: Animals; Biomarkers; Dipeptides; Environmental Monitoring; Erythrocytes; Ethylene Oxide; Globins; Hazardous Substances; Hydrolysis; Leucine; Rats; Valine

2019
Levels of Ethylene Oxide Biomarker in an Exposed Residential Community.
    International journal of environmental research and public health, 2020, 11-21, Volume: 17, Issue:22

    Topics: Adolescent; Adult; Aged; Biomarkers; Carcinogens; Child; Child, Preschool; Cotinine; Environmental Exposure; Ethylene Oxide; Female; Hemoglobin A; Hemoglobins; Humans; Infant; Infant, Newborn; Male; Middle Aged; North Carolina; Public Health Surveillance; Residence Characteristics; Smoking; Surveys and Questionnaires; Valine; Young Adult

2020