ethylene oxide has been researched along with n(7)-hydroxyethylguanine in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (7.69) | 18.7374 |
| 1990's | 14 (53.85) | 18.2507 |
| 2000's | 9 (34.62) | 29.6817 |
| 2010's | 1 (3.85) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fennell, TR; Prevost, V; Shuker, DE; Skopek, TR; Swenberg, JA; Upton, PB; Walker, VE | 1 |
| Baan, RA; van Delft, JH; van Weert, EJ; van Winden, MJ | 1 |
| Brimer, PA; Generoso, EE; Sega, GA | 1 |
| Allam, K; Giese, RW; Saha, M | 1 |
| Föst, U; Kasemann, R; Marczynski, B; Peter, H | 1 |
| Ashby, J; Greatbanks, D; Paton, D; Styles, JA; Wright, B | 1 |
| Abushamaa, A; Giese, RW; Saha, M | 1 |
| Skopek, TR; Walker, VE | 1 |
| Baan, RA; Luiten-Schuite, A; Ribeiro, LR; van Delft, JH; van Winden, MJ | 1 |
| Fennell, TR; MacNeela, JP; Swenberg, JA; Upton, PB; Walker, VE | 1 |
| Bolt, HM | 1 |
| De Pauw, E; Laurent, C; Leclercq, L | 1 |
| Bolt, HM; Golka, K; Leutbecher, M | 1 |
| Giese, R; Ranasinghe, A; Sangaiah, R; Scheller, N; Swenberg, JA; Wu, KY; Yen, TY | 1 |
| Ranasinghe, A; Swenberg, JA; Upton, PB; Walker, VE; Wu, KY | 1 |
| Ham, A; Koc, H; Morinello, E; Ranasinghe, A; Swenberg, JA; Tretyakova, N; Upton, PB; Wu, K | 1 |
| de Zwart, FA; Magnusson, AL; Natarajan, AT; Nilsen, A; Nilsen, OG; Tates, AD; Törnqvist, M; van Dam, FJ; van Sittert, NJ; van Teylingen, CM; Zahlsen, K; Zwinderman, AH | 1 |
| Boogaard, PJ; Ehrenberg, LG; Natarajan, AT; Tates, AD; Törnqvist, MA; van Sittert, NJ | 1 |
| Cho, MH; Ranasinghe, A; Scheller, N; Skopek, TR; Swenberg, JA; Upton, PB; Vergnes, JS; Walker, VE; Wu, KY | 1 |
| Chen, SH; Hung, CW; Li, CM; Liao, PC | 1 |
| Asakura, S; Koc, H; Kosyk, O; Li, Y; Nakamura, J; Rusyn, I; Swenberg, JA; Upton, PB | 1 |
| Brown, K; Farmer, PB; Jones, DJ; Lamb, JH; Marsden, DA; Tompkins, EM | 1 |
| Boeniger, MF; Giese, RW; Kao, CY; Petersen, MR; Schulte, PA; Strauss, GH; Wiencke, JK; Yong, LC | 1 |
| Chen, MF; Chen, YL; Huang, CC; Lin, YH; Shih, WC; Wu, CF; Wu, KY | 1 |
| Britton, RG; Brown, K; Farmer, PB; Johnson, GE; Jones, DJ; Marsden, DA; Ognibene, T; Ubick, E | 1 |
| Chen, CY; Chen, MF; Chiang, SY; Chien, YC; Huang, CC; Liou, SH; Shih, WC; Wu, CF; Wu, KY | 1 |
1 review(s) available for ethylene oxide and n(7)-hydroxyethylguanine
| Article | Year |
|---|---|
Quantification of endogenous carcinogens. The ethylene oxide paradox.
Topics: Animals; Carcinogens; DNA; Ethylene Oxide; Guanine; Hemoglobins; Humans; Valine | 1996 |
25 other study(ies) available for ethylene oxide and n(7)-hydroxyethylguanine
| Article | Year |
|---|---|
Molecular dosimetry of ethylene oxide: formation and persistence of 7-(2-hydroxyethyl)guanine in DNA following repeated exposures of rats and mice.
Topics: Administration, Inhalation; Animals; Chromatography, High Pressure Liquid; DNA; Dose-Response Relationship, Drug; Ethylene Oxide; Guanine; Male; Mice; Mice, Inbred C3H; Rats; Rats, Inbred F344; Tissue Distribution | 1992 |
Determination of N7-(2-hydroxyethyl)guanine by HPLC with electrochemical detection.
Topics: Animals; Chromatography, High Pressure Liquid; DNA; Dose-Response Relationship, Drug; Ethylene Oxide; Guanine; Salmon | 1991 |
Ethylene oxide inhalation at different exposure-rates affects binding levels in mouse germ cells and hemoglobin. Possible explanation for the effect.
Topics: Administration, Inhalation; Alkylation; Animals; Chromatography, High Pressure Liquid; DNA; DNA Repair; Ethylene Oxide; Guanine; Hemoglobins; Male; Mice; Spermatozoa; Testis | 1991 |
Preparation of electrophoric derivatives of N7-(2-hydroxyethyl)guanine, an ethylene oxide DNA adduct.
Topics: Chromatography, Gas; DNA; Electrons; Ethylene Oxide; Guanine; Humans | 1990 |
Determination of 7-(2-hydroxyethyl)guanine with gas chromatography/mass spectrometry as a parameter for genotoxicity of ethylene oxide.
Topics: Acetylcysteine; Alkylation; Animals; DNA; Ethylene Oxide; Gas Chromatography-Mass Spectrometry; Guanine; Histidine; Humans; Male; Mutagens; Rats; Rats, Inbred Strains | 1989 |
Synthesis of N7-hydroxyethylguanine and O6-hydroxyethylguanine. Markers for the reaction of ethylene oxide (EO) with DNA.
Topics: Chemical Phenomena; Chemistry; DNA; Ethylene Oxide; Guanine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mutagens | 1982 |
General method for determining ethylene oxide and related N7-guanine DNA adducts by gas chromatography-electron capture mass spectrometry.
Topics: DNA; DNA Adducts; Ethylene Oxide; Gas Chromatography-Mass Spectrometry; Guanine; Reference Standards | 1995 |
A mouse model for the study of in vivo mutational spectra: sequence specificity of ethylene oxide at the hprt locus.
Topics: Animals; Base Sequence; Cloning, Molecular; DNA; DNA Mutational Analysis; Electrophoresis, Polyacrylamide Gel; Ethylene Oxide; Exons; Female; Guanine; Hypoxanthine Phosphoribosyltransferase; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutagenicity Tests; Mutagens; Nucleic Acid Denaturation; Nucleic Acid Heteroduplexes; Point Mutation; Polymerase Chain Reaction; T-Lymphocytes | 1993 |
Comparison of various immunochemical assays for the detection of ethylene oxide-DNA adducts with monoclonal antibodies against imidazole ring-opened N7-(2-hydroxyethyl)guanosine: application in a biological monitoring study.
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Cell Nucleus; DNA; DNA Adducts; DNA Damage; Enzyme-Linked Immunosorbent Assay; Ethylene Oxide; Guanine; Humans; Immunohistochemistry; Leukocytes; Male; Mice; Mice, Inbred Strains; Microscopy, Fluorescence; Occupational Exposure; Sensitivity and Specificity | 1994 |
Molecular dosimetry of DNA and hemoglobin adducts in mice and rats exposed to ethylene oxide.
Topics: Animals; DNA; DNA Damage; Dose-Response Relationship, Drug; Ethylene Oxide; Guanine; Hemoglobins; Male; Mice; Rats; Rats, Inbred F344; Time Factors; Valine | 1993 |
High-performance liquid chromatography/electrospray mass spectrometry for the analysis of modified bases in DNA: 7-(2-hydroxyethyl)guanine, the major ethylene oxide-DNA adduct.
Topics: Animals; Cattle; Chromatography, High Pressure Liquid; DNA; DNA Adducts; Ethylene Oxide; Guanine; Humans; Lymphocytes; Mass Spectrometry | 1997 |
A note on the physiological background of the ethylene oxide adduct 7-(2-hydroxyethyl)guanine in DNA from human blood.
Topics: Chromatography, High Pressure Liquid; DNA Adducts; Ethylene Oxide; Guanine; Humans; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1997 |
A gas chromatography/electron capture/negative chemical ionization high-resolution mass spectrometry method for analysis of endogenous and exogenous N7-(2-hydroxyethyl)guanine in rodents and its potential for human biological monitoring.
Topics: Animals; Calibration; Chromatography, High Pressure Liquid; DNA; DNA Adducts; Ethylene Oxide; Gas Chromatography-Mass Spectrometry; Guanine; Humans; Hydroxylamines; Indicators and Reagents; Lymphocytes; Mice; Rats; Reference Standards; Spectrophotometry, Ultraviolet | 1999 |
Molecular dosimetry of endogenous and ethylene oxide-induced N7-(2-hydroxyethyl) guanine formation in tissues of rodents.
Topics: Animals; Brain Chemistry; Carcinogens; Chromatography, High Pressure Liquid; DNA; DNA Adducts; Dose-Response Relationship, Drug; Ethylene Oxide; Guanine; Liver; Lung; Male; Mice; Organ Specificity; Rats; Rats, Inbred F344; Spleen | 1999 |
DNA adducts: effects of low exposure to ethylene oxide, vinyl chloride and butadiene.
Topics: Animals; Butadienes; Carcinogens; DNA Adducts; Dose-Response Relationship, Drug; Ethylene Oxide; Gas Chromatography-Mass Spectrometry; Guanine; Mice; Mice, Inbred Strains; Organ Specificity; Rats; Rats, Inbred Strains; Vinyl Chloride | 2000 |
Measurement of HPRT mutations in splenic lymphocytes and haemoglobin adducts in erythrocytes of Lewis rats exposed to ethylene oxide.
Topics: Administration, Inhalation; Administration, Oral; Animals; Carcinogens; Chromosome Aberrations; DNA Adducts; Erythrocytes; Ethylene Oxide; Ethylnitrosourea; Guanine; Hemoglobins; Hypoxanthine Phosphoribosyltransferase; Injections, Intraperitoneal; Lymphocytes; Male; Micronucleus Tests; Mutation; Rats; Rats, Inbred Lew; Sister Chromatid Exchange; Spleen | 1999 |
Formation of DNA adducts and induction of mutagenic effects in rats following 4 weeks inhalation exposure to ethylene oxide as a basis for cancer risk assessment.
Topics: Administration, Inhalation; Animals; Chromosome Aberrations; DNA Adducts; Ethylene Oxide; Guanine; Hemoglobins; Humans; Hypoxanthine Phosphoribosyltransferase; Liver; Male; Micronucleus Tests; Mutagens; Mutation; Neoplasms, Experimental; Rats; Rats, Inbred Lew; Risk Assessment; Sister Chromatid Exchange | 2000 |
Biomarkers of exposure and effect as indicators of potential carcinogenic risk arising from in vivo metabolism of ethylene to ethylene oxide.
Topics: Animals; Biomarkers; Biotransformation; Carcinogens; DNA; DNA Damage; Dose-Response Relationship, Drug; Ethylene Oxide; Ethylenes; Guanine; Hemoglobins; Hypoxanthine Phosphoribosyltransferase; Inhalation Exposure; Male; Mice; Mice, Inbred Strains; Mutation; Rats; Rats, Inbred F344; T-Lymphocytes; Valine | 2000 |
Quantitative detection of N(7)-(2-hydroxyethyl)guanine adducts in DNA using high-performance liquid chromatography/electrospray ionization tandem mass spectrometry.
Topics: Carcinoma, Hepatocellular; Chromatography, High Pressure Liquid; DNA Adducts; DNA, Neoplasm; Dose-Response Relationship, Drug; Ethylene Oxide; Guanine; Humans; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tumor Cells, Cultured | 2001 |
Effects of ethylene oxide and ethylene inhalation on DNA adducts, apurinic/apyrimidinic sites and expression of base excision DNA repair genes in rat brain, spleen, and liver.
Topics: Administration, Inhalation; Animals; Apoptosis; Brain; Brain Chemistry; DNA; DNA Adducts; DNA Repair; Ethylene Oxide; Ethylenes; Gene Expression; Guanine; Liver; Male; Rats; Rats, Inbred F344; Spleen | 2005 |
Determination of endogenous and exogenously derived N7-(2-hydroxyethyl)guanine adducts in ethylene oxide-treated rats.
Topics: Animals; Chromatography, Liquid; DNA Adducts; Dose-Response Relationship, Drug; Ethylene Oxide; Guanine; Injections, Intraperitoneal; Male; Molecular Structure; Rats; Rats, Inbred F344; Sensitivity and Specificity; Tandem Mass Spectrometry; Time Factors; Tissue Distribution | 2007 |
DNA adducts in granulocytes of hospital workers exposed to ethylene oxide.
Topics: Adult; DNA Adducts; Ethylene Oxide; Female; Gas Chromatography-Mass Spectrometry; Genotype; Granulocytes; Guanine; Humans; Male; Mexico; Middle Aged; Occupational Exposure; Personnel, Hospital; Pilot Projects; United States | 2007 |
Rapid and sensitive on-line liquid chromatographic/tandem mass spectrometric determination of an ethylene oxide-DNA adduct, N7-(2-hydroxyethyl)guanine, in urine of nonsmokers.
Topics: Air Pollutants; Biomarkers; Chromatography, High Pressure Liquid; DNA; DNA Adducts; Ethylene Oxide; Guanine; Humans; Reference Values; Smoking; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2008 |
Dose-response relationships for N7-(2-hydroxyethyl)guanine induced by low-dose [14C]ethylene oxide: evidence for a novel mechanism of endogenous adduct formation.
Topics: Amino Acids, Cyclic; Animals; Biomarkers; Carbon Radioisotopes; Chromatography, High Pressure Liquid; DNA Adducts; Dose-Response Relationship, Drug; Ethylene Oxide; Guanine; Male; Oxidative Stress; Rats; Rats, Inbred F344; Tandem Mass Spectrometry; Tissue Distribution | 2009 |
Comparative analysis of urinary N7-(2-hydroxyethyl)guanine for ethylene oxide- and non-exposed workers.
Topics: Adult; Biomarkers; Disinfectants; DNA Adducts; Environmental Monitoring; Ethylene Oxide; Female; Guanine; High-Throughput Screening Assays; Humans; Industry; Male; Occupational Exposure; Personnel, Hospital; Solid Phase Extraction | 2011 |