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ethylene oxide and chloroethylene oxide

ethylene oxide has been researched along with chloroethylene oxide in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199015 (50.00)18.7374
1990's10 (33.33)18.2507
2000's4 (13.33)29.6817
2010's0 (0.00)24.3611
2020's1 (3.33)2.80

Authors

AuthorsStudies
Crawford, WM; Guengerich, FP; Watanabe, PG1
Elmore, JD; Laumbach, AD; Streips, UN; Wong, JL1
Border, EA; Webster, I1
Csanády, G; Peter, H1
Barbin, A; Bartsch, H; Béréziat, JC; Croisy, A; O'Neill, IK1
Laib, RJ1
Barbin, A; Bartsch, H1
Bolt, HM1
Barbin, A; Bartsch, H; Friesen, M; O'Neill, I1
Perrard, MH1
Barbin, A; Bartsch, H; Laib, RJ1
Bolt, HM; Filser, JG; Gwinner, LM; Laib, RJ1
Hussain, S; Osterman-Golkar, S1
Barbin, A; Bartsch, H; Leconte, P; Radman, M1
Emmelot, P; Gwinner, LM; Laib, RJ; Scherer, E; Van der Laken, CJ1
Rice, JM1
Barbin, A; Bartsch, H; Croisy, A; Malaveille, C; Tomatis, L; Zajdela, F1
Kuśmierek, JT; Mroczkowska-Słupska, MM1
Ballering, LA; Nivard, MJ; Vogel, EW1
Moriya, M; Pandya, GA1
Belas, F; Guengerich, FP; Müller, M; Ueno, H1
Belas, FJ; Blair, IA; Guengerich, FP; Müller, M1
Chiang, SY; Skopek, TR; Swenberg, JA; Weisman, WH1
Holt, S; Sangaiah, R; Swenberg, JA; Yen, TY1
Akasaka, S; Guengerich, FP; Langouët, S; Mican, AN; Müller, M; Persmark, M1
Harris, CM; Harris, TM; Nechev, LV1
Coleman, NV; Spain, JC1
Bren, U; Guengerich, FP; Mavri, J; Zupan, M1
Cheeseman, JR; Luderer, MR; Vaccaro, PH; Wang, YG; Wiberg, KB; Wilson, SM1
Bren, U; Furlan, V1

Reviews

2 review(s) available for ethylene oxide and chloroethylene oxide

ArticleYear
[Molecular basis of mutagenic activity of vinyl chloride].
    Postepy biochemii, 1994, Volume: 40, Issue:1

    Topics: Acetaldehyde; Animals; Carcinogens; Cytochrome P-450 Enzyme System; DNA Repair; Ethylene Oxide; Genetic Code; Humans; Mutagens; Nucleic Acids; Vinyl Chloride

1994
Formation of etheno adducts and their effects on DNA polymerases.
    IARC scientific publications, 1999, Issue:150

    Topics: Animals; Base Sequence; CHO Cells; Cricetinae; DNA; DNA Adducts; DNA-Directed DNA Polymerase; Dose-Response Relationship, Drug; Escherichia coli; Ethylene Oxide; Guanosine; Kinetics; Models, Chemical; Molecular Sequence Data; Mutation

1999

Other Studies

28 other study(ies) available for ethylene oxide and chloroethylene oxide

ArticleYear
Activation of vinyl chloride to covalently bound metabolites: roles of 2-chloroethylene oxide and 2-chloroacetaldehyde.
    Biochemistry, 1979, Nov-13, Volume: 18, Issue:23

    Topics: Acetaldehyde; Alcohol Oxidoreductases; Animals; Cytochrome P-450 Enzyme System; Epoxide Hydrolases; Ethylene Oxide; Kinetics; Male; Microsomes, Liver; Phenobarbital; Rats; Vinyl Chloride; Vinyl Compounds

1979
Vinyl chloride mutagenicity via the metabolites chlorooxirane and chloroacetaldehyde monomer hydrate.
    Biochimica et biophysica acta, 1976, Sep-06, Volume: 442, Issue:3

    Topics: Acetaldehyde; Bacillus subtilis; Carcinogens; Chlorohydrins; Dose-Response Relationship, Drug; Epichlorohydrin; Epoxy Compounds; Ethers, Cyclic; Ethylene Chlorohydrin; Ethylene Oxide; Models, Chemical; Mutagens; Mutation; Salmonella typhimurium; Species Specificity; Vinyl Chloride; Vinyl Compounds

1976
The effect of vinyl chloride monomer, chloroethylene oxide and chloracetaldehyde on DNA synthesis in regenerating rat liver.
    Chemico-biological interactions, 1977, Volume: 17, Issue:2

    Topics: Acetaldehyde; Animals; DNA; Ethylene Oxide; Kinetics; Liver; Liver Regeneration; Rats; Vinyl Chloride; Vinyl Compounds

1977
Note on the preference of aliphatic epoxides for the N-7 position of guanine in DNA.
    Archives of toxicology, 1990, Volume: 64, Issue:6

    Topics: Adenine; Alkylating Agents; Alkylation; DNA; Epoxy Compounds; Ethylene Oxide; Guanine; Hydrogen Bonding

1990
Nucleophilic selectivity and reaction kinetics of chloroethylene oxide assessed by the 4-(p-nitrobenzyl)pyridine assay and proton nuclear magnetic resonance spectroscopy.
    Chemico-biological interactions, 1990, Volume: 73, Issue:2-3

    Topics: Acetaldehyde; Anions; Carcinogens; Chemical Phenomena; Chemistry; Chlorides; Deuterium; Ethylene Oxide; Indicators and Reagents; Kinetics; Magnetic Resonance Spectroscopy; Pyridines; Temperature; Thiosulfates

1990
The role of cyclic base adducts in vinyl-chloride-induced carcinogenesis: studies on nucleic acid alkylation in vivo.
    IARC scientific publications, 1986, Issue:70

    Topics: Acetaldehyde; Adenine; Alkylation; Animals; Carcinogens; Cytosine; DNA; DNA Damage; Ethylene Oxide; Guanine; Microsomes, Liver; Rats; RNA; Vinyl Chloride; Vinyl Compounds

1986
Mutagenic and promutagenic properties of DNA adducts formed by vinyl chloride metabolites.
    IARC scientific publications, 1986, Issue:70

    Topics: Acetaldehyde; Adenine; Alkylating Agents; Animals; Carcinogens; Cytosine; DNA Damage; DNA Replication; Dose-Response Relationship, Drug; Escherichia coli; Ethylene Oxide; Guanine; Mutagens; Vinyl Chloride; Vinyl Compounds

1986
Metabolic activation of vinyl chloride, formation of nucleic acid adducts and relevance to carcinogenesis.
    IARC scientific publications, 1986, Issue:70

    Topics: Animals; Biotransformation; Carcinogens; Cytochrome P-450 Enzyme System; DNA; DNA Damage; Epoxy Compounds; Ethylene Oxide; Glutathione; Kinetics; Microsomes, Liver; Proteins; Vinyl Chloride; Vinyl Compounds

1986
Reaction kinetics and cytosine adducts of chloroethylene oxide and chloroacetaldehyde: direct observation of intermediates by FTNMR and GC-MS.
    IARC scientific publications, 1986, Issue:70

    Topics: 5-Methylcytosine; Acetaldehyde; Chemical Phenomena; Chemistry; Cytidine; Cytosine; DNA; DNA Damage; Ethylene Oxide; Gas Chromatography-Mass Spectrometry; Hydrolysis; Kinetics; Magnetic Resonance Spectroscopy; Uridine

1986
Mutagenicity and toxicity of chloroethylene oxide and chloroacetaldehyde.
    Experientia, 1985, May-15, Volume: 41, Issue:5

    Topics: Acetaldehyde; Escherichia coli; Ethylene Oxide; Mutagens; Tryptophan

1985
Lack of miscoding properties of 7-(2-oxoethyl)guanine, the major vinyl chloride-DNA adduct.
    Cancer research, 1985, Volume: 45, Issue:6

    Topics: Chromatography, High Pressure Liquid; Deoxyadenine Nucleotides; DNA; DNA Replication; Ethylene Oxide; Guanine; Polydeoxyribonucleotides; Thymidine Monophosphate; Vinyl Chloride

1985
Evidence of chloroethylene oxide being the reactive metabolite of vinyl chloride towards DNA: comparative studies with 2,2'-dichlorodiethylether.
    Carcinogenesis, 1983, Volume: 4, Issue:11

    Topics: Animals; Biotransformation; Carbon Radioisotopes; DNA; Ether; Ethyl Ethers; Ethylene Oxide; Kinetics; Liver; Male; Protein Binding; Proteins; Rats; Rats, Inbred Strains; RNA; Structure-Activity Relationship; Tissue Distribution; Vinyl Chloride; Vinyl Compounds

1983
Dose-response relationships for mutations induced in E. coli by some model compounds. With an addendum: Reaction kinetics in water of chloroethylene oxide, chloroacetaldehyde, and chloroacetone.
    Hereditas, 1984, Volume: 101, Issue:1

    Topics: Acetaldehyde; Acetone; Dose-Response Relationship, Drug; Escherichia coli; Ethylene Oxide; Kinetics; Mutagens; Water

1984
Studies on the miscoding properties of 1,N6-ethenoadenine and 3,N4-ethenocytosine, DNA reaction products of vinyl chloride metabolites, during in vitro DNA synthesis.
    Nucleic acids research, 1981, Jan-24, Volume: 9, Issue:2

    Topics: Acetaldehyde; Biotransformation; DNA Polymerase I; DNA Replication; DNA-Directed DNA Polymerase; Escherichia coli; Ethylene Oxide; Polydeoxyribonucleotides; Templates, Genetic; Vinyl Chloride; Vinyl Compounds

1981
Modification of deoxyguanosine by chloroethylene oxide.
    Carcinogenesis, 1981, Volume: 2, Issue:7

    Topics: Borohydrides; Chemical Phenomena; Chemistry; Deoxyguanosine; Ethylene Oxide; Spectrophotometry, Ultraviolet

1981
Prenatal susceptibility to carcinogenesis by xenobiotic substances including vinyl chloride.
    Environmental health perspectives, 1981, Volume: 41

    Topics: Animals; Biotransformation; Cercopithecidae; Ethylene Oxide; Ethylnitrosourea; Female; Maternal-Fetal Exchange; Mice; Neoplasms, Experimental; Pregnancy; Rats; Rats, Inbred Strains; Vinyl Chloride; Vinyl Compounds

1981
Carcinogenicity of chloroethylene oxide, an ultimate reactive metabolite of vinyl chloride, and bis(chloromethyl)ether after subcutaneous administration and in initiation-promotion experiments in mice.
    Cancer research, 1980, Volume: 40, Issue:2

    Topics: Animals; Bis(Chloromethyl) Ether; Ethylene Oxide; Female; Male; Methyl Ethers; Mice; Mutagens; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Soft Tissue Neoplasms; Tetradecanoylphorbol Acetate; Vinyl Chloride

1980
Characterization by two-endpoint comparisons of the genetic toxicity profiles of vinyl chloride and related etheno-adduct forming carcinogens in Drosophila.
    Carcinogenesis, 1996, Volume: 17, Issue:5

    Topics: Animals; Carcinogens; Cross-Linking Reagents; Drosophila melanogaster; Ethylene Oxide; Male; Mutagens; Mutation; Structure-Activity Relationship; Vinyl Chloride

1996
1,N6-ethenodeoxyadenosine, a DNA adduct highly mutagenic in mammalian cells.
    Biochemistry, 1996, Sep-03, Volume: 35, Issue:35

    Topics: Acetaldehyde; Animals; Base Sequence; Cell Line; Chromatography, High Pressure Liquid; Cloning, Molecular; Deoxyadenosines; Deoxycytidine; DNA Adducts; DNA, Single-Stranded; Escherichia coli; Ethylene Oxide; Humans; Molecular Sequence Data; Mutagens; Mutation; Nucleic Acid Conformation; Plasmids; Transformation, Genetic

1996
Development of a mass spectrometric assay for 5,6,7,9-tetrahydro-7-hydroxy-9-oximidazo[1,2-alpha] purine in DNA modified by 2-chloro-oxirane.
    Advances in experimental medicine and biology, 1996, Volume: 387

    Topics: Animals; Cattle; Chromatography, Liquid; DNA Adducts; Ethylene Oxide; Imidazoles; Indicators and Reagents; Isotope Labeling; Mass Spectrometry; Purines

1996
Analysis of 1,N2-ethenoguanine and 5,6,7,9-tetrahydro-7-hydroxy-9-oxoimidazo[1,2-a]purine in DNA treated with 2-chlorooxirane by high performance liquid chromatography/electrospray mass spectrometry and comparison of amounts to other DNA adducts.
    Chemical research in toxicology, 1997, Volume: 10, Issue:2

    Topics: Animals; Cattle; Chromatography, High Pressure Liquid; DNA; DNA Adducts; Ethylene Oxide; Fishes; Gas Chromatography-Mass Spectrometry; Guanosine; Imidazoles; Male; Purines; Spermatozoa; Thymus Gland

1997
Mutagenicity of vinyl chloride and its reactive metabolites, chloroethylene oxide and chloroacetaldehyde, in a metabolically competent human B-lymphoblastoid line.
    Carcinogenesis, 1997, Volume: 18, Issue:1

    Topics: Acetaldehyde; B-Lymphocytes; Cell Line; Dose-Response Relationship, Drug; Ethylene Oxide; Humans; Hypoxanthine Phosphoribosyltransferase; Mutagenicity Tests; Mutation; Time Factors; Vinyl Chloride

1997
Detection of 1,N6-ethenoadenine in rat urine after chloroethylene oxide exposure.
    Carcinogenesis, 1998, Volume: 19, Issue:10

    Topics: Adenine; Animals; Chromatography, Affinity; Chromatography, High Pressure Liquid; Ethylene Oxide; Injections, Intravenous; Male; Mass Spectrometry; Mutagens; Rats; Rats, Inbred F344; Spectrometry, Fluorescence

1998
Synthesis of nucleosides and oligonucleotides containing adducts of acrolein and vinyl chloride.
    Chemical research in toxicology, 2000, Volume: 13, Issue:5

    Topics: Acrolein; Chromatography, High Pressure Liquid; Deoxyadenosines; Deoxyguanosine; DNA; DNA Adducts; Ethylene Oxide; Mutagens; Nucleosides; Oligonucleotides; Vinyl Chloride

2000
Epoxyalkane: coenzyme M transferase in the ethene and vinyl chloride biodegradation pathways of mycobacterium strain JS60.
    Journal of bacteriology, 2003, Volume: 185, Issue:18

    Topics: Amino Acid Sequence; Biodegradation, Environmental; Carbon-Sulfur Lyases; Cell Division; Cloning, Molecular; DNA, Intergenic; Ethylene Oxide; Ethylenes; Gene Expression Regulation, Bacterial; Molecular Sequence Data; Mycobacterium; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Vinyl Chloride

2003
Chemical reactivity as a tool to study carcinogenicity: reaction between chloroethylene oxide and guanine.
    The Journal of organic chemistry, 2006, May-26, Volume: 71, Issue:11

    Topics: Carcinogens; Energy Transfer; Ethylene Oxide; Guanine; Molecular Structure; Structure-Activity Relationship; Thermodynamics

2006
Effect of substituents and conformations on the optical rotations of cyclic oxides and related compounds. relationship between the anomeric effect and optical rotation.
    The Journal of organic chemistry, 2007, Aug-03, Volume: 72, Issue:16

    Topics: Carbon; Chemistry, Organic; Chlorine; Cyclopropanes; Ethylene Oxide; Furans; Models, Chemical; Models, Statistical; Models, Theoretical; Molecular Conformation; Nitrogen; Oxides; Oxygen

2007
Protective Effects of [6]-Gingerol Against Chemical Carcinogens: Mechanistic Insights.
    International journal of molecular sciences, 2020, Jan-21, Volume: 21, Issue:3

    Topics: Aflatoxin B1; Alkylation; Anticarcinogenic Agents; Carcinogens; Catechols; Cell Line; Chemoprevention; Epoxy Compounds; Ethylene Oxide; Fatty Alcohols; Humans; Propiolactone; Urethane; Zingiber officinale

2020