Page last updated: 2024-08-17

ethylene oxide and acrylonitrile

ethylene oxide has been researched along with acrylonitrile in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199013 (37.14)18.7374
1990's11 (31.43)18.2507
2000's7 (20.00)29.6817
2010's4 (11.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vettorazzi, G1
Courtney, JM; Forbes, CD; Park, GB; Prentice, CR; Winchester, JF1
Courtney, J; Edwards, RO; Gilchrist, T; Lindsay, RM; Linton, AL; Reid, BD; Rourke, JT1
Kedderis, GL; Rickert, DE; Roberts, AE; Swenberg, JA; Turner, MJ1
Guengerich, FP; Hogy, LL1
Brodeur, J; Goyal, R; Tardif, R1
Segal, A; Solomon, JJ1
Recio, L; Skopek, TR1
Linhart, I; Novák, J; Smejkal, J1
Brodeur, J; Gérin, M; Tardif, R1
Geiger, LE; Guengerich, FP; Hogy, LL; Wright, PL1
Appel, KE; Bolt, HM; Mathiasch, B; Peter, H; Schwarz, M1
Holecek, V; Kopecký, J1
Muthu, M; Rajendran, S1
Batra, R; Kedderis, GL; Turner, MJ1
Andersen, ME; Batra, R; Fennell, TR; Gargas, ML; Kedderis, GL; Teo, SK1
Gargas, ML; Kedderis, GL; Teo, SK1
Batra, R; Held, SD; Kedderis, GL; Loos, MA; Teo, SK1
Batra, R; Fennell, TR; Held, SD; Kedderis, GL; Roberts, AE; Sumner, SC; Turner, MJ1
Batra, R; Gargas, ML; Held, SD; Kedderis, GL; Teo, SK1
Farmer, PB; Lawrence, RM; Sweetman, GM; Tavares, R1
Klaustermeyer, WB; Kraske, GK; Shinaberger, JH1
Bergmark, E1
Blair, A; Kazerouni, N1
Gargas, ML; Hays, SM; Kedderis, GL; Kirman, CR; Strother, DE1
Bell, DA; Fennell, TR; MacNeela, JP; Morris, RW; Thompson, CL; Watson, M1
Balkenhol, H; Bolt, HM; Dommermuth, A; Lewalter, J; Selinski, S; Thier, R1
Angerer, J; Broding, HC; Drexler, H; Schettgen, T1
Gargas, ML; Kedderis, GL; Strother, DE; Sweeney, LM1
de los Angeles Elías, M; Garcia, G; Herrero, VM; Martínez, SA; Morales, MA; Rodríguez, MG; Valdivieso, E1
Charrier, JG; Hafner, HR; McCarthy, MC; O'Brien, TE1
Angerer, J; Fromme, H; Müller, J; Schettgen, T1
Bertram, J; Kraus, T; Schettgen, T1
Bren, U; Gladovic, M; Spaninger, E1
Checkoway, H; Dell, LD; Gentry, PR; Lees, PSJ; Mundt, KA1

Reviews

3 review(s) available for ethylene oxide and acrylonitrile

ArticleYear
State of the art of the toxicological evaluation carried out by the joint FAO/WHO expert committee on pesticide residues. III. Miscellaneous pesticides used in agriculture and public health.
    Residue reviews, 1977, Volume: 66

    Topics: Acrylonitrile; Amitrole; Animals; Arsenates; Butylamines; Carbon Disulfide; Carbon Tetrachloride; Dinitrophenols; Ethoxyquin; Ethylene Oxide; Hydrocarbons, Brominated; Hydrogen Cyanide; Indoles; Nitrobenzenes; Organometallic Compounds; Pesticides; Piperonyl Butoxide; Pyridines; Quaternary Ammonium Compounds; Thiabendazole; Thiocarbamates; World Health Organization

1977
Reactive chemicals and cancer.
    Cancer causes & control : CCC, 1997, Volume: 8, Issue:3

    Topics: Acrylonitrile; Air Pollutants; Animals; Bis(Chloromethyl) Ether; Butadienes; Carcinogens; Cohort Studies; England; Environmental Exposure; Ethylene Oxide; Follow-Up Studies; Formaldehyde; Hemangiosarcoma; Humans; Laryngeal Neoplasms; Leukemia; Liver Neoplasms; Lung Neoplasms; Methyl Ethers; Mustard Gas; Nasopharyngeal Neoplasms; Neoplasms; Neoplasms, Experimental; Nose Neoplasms; Occupational Diseases; Occupational Exposure; Organic Chemicals; Risk Factors; Sulfuric Acids; Sweden; Vinyl Chloride

1997
Peak Exposures in Epidemiologic Studies and Cancer Risks: Considerations for Regulatory Risk Assessment.
    Risk analysis : an official publication of the Society for Risk Analysis, 2019, Volume: 39, Issue:7

    Topics: Acrylonitrile; Air Pollutants; Benzene; Environmental Exposure; Epidemiologic Studies; Ethylene Oxide; Formaldehyde; Humans; Leukemia; Lymphoma; Methylene Chloride; Neoplasms; Risk Assessment; Styrene; Trichloroethylene; United States; United States Environmental Protection Agency

2019

Other Studies

32 other study(ies) available for ethylene oxide and acrylonitrile

ArticleYear
Polymer modification and blood compatibility.
    Journal of bioengineering, 1978, Volume: 2, Issue:3-4

    Topics: Acrylonitrile; Biocompatible Materials; Blood; Chemical Phenomena; Chemistry; Chemistry, Physical; Ethylene Oxide; Heparin; Humans; Methacrylates; Molecular Conformation; Polymers

1978
The role of heparin on platelet retention by acrylonitrile co-polymer dialysis membranes.
    The Journal of laboratory and clinical medicine, 1977, Volume: 89, Issue:4

    Topics: Acrylates; Acrylonitrile; Blood Platelets; Ethylene Oxide; Heparin; Membranes, Artificial; Methacrylates; Nitriles; Platelet Adhesiveness

1977
Species comparison of acrylonitrile epoxidation by microsomes from mice, rats and humans: relationship to epoxide concentrations in mouse and rat blood.
    Carcinogenesis, 1991, Volume: 12, Issue:3

    Topics: Acrylonitrile; Animals; Carcinogens; Dose-Response Relationship, Drug; Epoxy Compounds; Ethylene Oxide; Humans; Kinetics; Lung; Male; Mice; Mice, Inbred Strains; Microsomes; Microsomes, Liver; Oxidation-Reduction; Rats; Rats, Inbred F344; Species Specificity

1991
In vivo interaction of acrylonitrile and 2-cyanoethylene oxide with DNA in rats.
    Cancer research, 1986, Volume: 46, Issue:8

    Topics: Acrylonitrile; Alkylation; Animals; DNA; DNA Repair; DNA Replication; Ethylene Oxide; Liver; Male; Mutagens; Nitriles; Perfusion; Rats; Rats, Inbred F344; RNA

1986
Influence of a cysteine prodrug, L-2-oxothiazolidine-4-carboxylic acid, on the urinary elimination of mercapturic acids of ethylene oxide, dibromoethane, and acrylonitrile: a dose-effect study.
    Canadian journal of physiology and pharmacology, 1989, Volume: 67, Issue:3

    Topics: Acetylcysteine; Acrylonitrile; Animals; Ethylene Dibromide; Ethylene Oxide; Glutathione; Hydrocarbons, Brominated; Kidney; Liver; Male; Nitriles; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines; Time Factors

1989
DNA adducts of propylene oxide and acrylonitrile epoxide: hydrolytic deamination of 3-alkyl-dCyd to 3-alkyl-dUrd.
    Environmental health perspectives, 1989, Volume: 81

    Topics: Acrylonitrile; Animals; Carcinogens; Cattle; Chemical Phenomena; Chemistry; Deamination; Deoxycytidine; Deoxyuridine; DNA; Epoxy Compounds; Ethers, Cyclic; Ethylene Oxide; Hydrogen-Ion Concentration; Nitriles

1989
Mutagenicity of acrylonitrile and its metabolite 2-cyanoethylene oxide in human lymphoblasts in vitro.
    Mutation research, 1988, Volume: 206, Issue:2

    Topics: Acrylonitrile; Animals; Biotransformation; Cells, Cultured; Ethylene Oxide; Genetic Markers; Humans; Lymphocytes; Male; Microsomes, Liver; Mutagenicity Tests; Mutagens; Nitriles; Rats; Rats, Inbred Strains; Thymidine Kinase

1988
N-acetyl-S-(1-cyano-2-hydroxyethyl)-L-cysteine, a new urinary metabolite of acrylonitrile and oxiranecarbonitrile.
    Archives of toxicology, 1988, Volume: 61, Issue:6

    Topics: Acetylcysteine; Acrylonitrile; Animals; Biotransformation; Ethylene Oxide; Female; Nitriles; Rats; Rats, Inbred Strains; Stereoisomerism; Thiazines

1988
Determination of specific urinary thioethers derived from acrylonitrile and ethylene oxide.
    IARC scientific publications, 1988, Issue:89

    Topics: Acetylcysteine; Acrylonitrile; Animals; Cysteine; Environmental Monitoring; Ethylene Oxide; Nitriles; Rats; Rats, Inbred Strains

1988
In vitro metabolism of acrylonitrile to 2-cyanoethylene oxide, reaction with glutathione, and irreversible binding to proteins and nucleic acids.
    Cancer research, 1981, Volume: 41, Issue:12 Pt 1

    Topics: Acrylonitrile; Animals; Biotransformation; DNA; Ethylene Oxide; Glutathione; Hydrogen Cyanide; Inactivation, Metabolic; Male; Microsomes, Liver; Mixed Function Oxygenases; Nitriles; Protein Binding; Rats

1981
A note on synthesis and reactivity towards DNA of glycidonitrile, the epoxide of acrylonitrile.
    Carcinogenesis, 1983, Volume: 4, Issue:2

    Topics: Acrylonitrile; DNA Replication; DNA, Viral; Epoxy Compounds; Ethylene Oxide; Magnetic Resonance Spectroscopy; Nitriles; Simian virus 40; Structure-Activity Relationship

1983
Conjugations of acrylonitrile and glycidonitrile with glutathione--a contribution to problems of metabolism of acrylonitrile.
    Czechoslovak medicine, 1983, Volume: 6, Issue:2

    Topics: Acrylonitrile; Animals; Chemical Phenomena; Chemistry; Ethylene Oxide; Glutathione; Guinea Pigs; Humans; In Vitro Techniques; Liver; Mice; Nitriles; Rabbits; Rats

1983
Detection of acrylonitrile and ethylene oxide in air and fumigated foodstuffs.
    Bulletin of environmental contamination and toxicology, 1981, Volume: 27, Issue:3

    Topics: Acrylonitrile; Air Pollutants; Chromatography, Gas; Ethylene Oxide; Food Analysis; Fumigation; Indicators and Reagents; Nitriles

1981
Conjugation of acrylonitrile and 2-cyanoethylene oxide with hepatic glutathione.
    Toxicology and applied pharmacology, 1995, Volume: 135, Issue:1

    Topics: Acrylonitrile; Animals; Carcinogens; Cytosol; Ethylene Oxide; Glutathione; Humans; Mice; Microsomes, Liver; Rats; Rats, Inbred F344; Subcellular Fractions

1995
A physiologically based dosimetry description of acrylonitrile and cyanoethylene oxide in the rat.
    Toxicology and applied pharmacology, 1995, Volume: 134, Issue:2

    Topics: Acrylonitrile; Animals; Carcinogens; Dose-Response Relationship, Drug; Ethylene Oxide; Glutathione; Male; Rats; Rats, Inbred F344

1995
Determination of tissue partition coefficients for volatile tissue-reactive chemicals: acrylonitrile and its metabolite 2-cyanoethylene oxide.
    Toxicology and applied pharmacology, 1994, Volume: 128, Issue:1

    Topics: Acrylonitrile; Animals; Carcinogens; Ethylene Oxide; Liver; Male; Models, Biological; Rats; Rats, Inbred F344; Solubility; Tissue Distribution

1994
Rodent tissue distribution of 2-cyanoethylene oxide, the epoxide metabolite of acrylonitrile.
    Toxicology letters, 1993, Volume: 69, Issue:1

    Topics: Acrylonitrile; Administration, Oral; Animals; Brain Chemistry; Carcinogens; Ethylene Oxide; Male; Mice; Rats; Rats, Inbred F344; Species Specificity; Tissue Distribution

1993
Dose-dependent urinary excretion of acrylonitrile metabolites by rats and mice.
    Toxicology and applied pharmacology, 1993, Volume: 120, Issue:2

    Topics: Acrylonitrile; Administration, Oral; Animals; Carcinogens; Chromatography, High Pressure Liquid; Ethylene Oxide; Male; Mice; Rats; Rats, Inbred F344; Species Specificity

1993
Refinement and verification of the physiologically based dosimetry description for acrylonitrile in rats.
    Toxicology and applied pharmacology, 1996, Volume: 140, Issue:2

    Topics: Acrylonitrile; Administration, Inhalation; Administration, Oral; Animals; Brain Chemistry; Dose-Response Relationship, Drug; Ethylene Oxide; Injections, Intravenous; Kinetics; Liver; Male; Organ Specificity; Rats; Rats, Inbred F344; Sensitivity and Specificity

1996
Synthesis and characterization of peptide adducts for use in monitoring human exposure to acrylonitrile and ethylene oxide.
    Teratogenesis, carcinogenesis, and mutagenesis, 1996, Volume: 16, Issue:3

    Topics: Acrylonitrile; Environmental Monitoring; Ethylene Oxide; Hemoglobins; Magnetic Resonance Spectroscopy; Mass Spectrometry; Peptides

1996
Severe hypersensitivity reaction during hemodialysis.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 1997, Volume: 78, Issue:2

    Topics: Acrylonitrile; Aged; Anaphylaxis; Ethylene Oxide; Humans; Hypersensitivity, Immediate; Male; Membranes, Artificial; Peritoneal Dialysis; Radioallergosorbent Test; Renal Dialysis; Sterilization

1997
Hemoglobin adducts of acrylamide and acrylonitrile in laboratory workers, smokers and nonsmokers.
    Chemical research in toxicology, 1997, Volume: 10, Issue:1

    Topics: Acrylamide; Acrylamides; Acrylonitrile; Adult; Ethylene Oxide; Female; Gas Chromatography-Mass Spectrometry; Hemoglobins; Humans; Laboratories; Male; Middle Aged; Occupational Exposure; Smoking

1997
Improving cancer dose-response characterization by using physiologically based pharmacokinetic modeling: an analysis of pooled data for acrylonitrile-induced brain tumors to assess cancer potency in the rat.
    Risk analysis : an official publication of the Society for Risk Analysis, 2000, Volume: 20, Issue:1

    Topics: Acrylonitrile; Air Pollutants; Animals; Biological Assay; Brain; Brain Neoplasms; Carcinogens; Databases as Topic; Dose-Response Relationship, Drug; Environmental Exposure; Ethylene Oxide; Forecasting; Guidelines as Topic; Linear Models; Models, Biological; Nonlinear Dynamics; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Risk Assessment; United States; United States Environmental Protection Agency; Water Pollutants, Chemical

2000
Hemoglobin adducts from acrylonitrile and ethylene oxide in cigarette smokers: effects of glutathione S-transferase T1-null and M1-null genotypes.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2000, Volume: 9, Issue:7

    Topics: Acrylonitrile; Carcinogens; Cross-Sectional Studies; Disinfectants; DNA Adducts; Ethylene Oxide; Genotype; Glutathione Transferase; Hemoglobins; Humans; Immunoassay; Polymorphism, Genetic; Smoking

2000
Influence of polymorphisms of the human glutathione transferases and cytochrome P450 2E1 enzyme on the metabolism and toxicity of ethylene oxide and acrylonitrile.
    Mutation research, 2001, Oct-01, Volume: 482, Issue:1-2

    Topics: Acrylonitrile; Carcinogens; Cytochrome P-450 CYP2E1; DNA Adducts; Ethylene Oxide; Glutathione S-Transferase pi; Glutathione Transferase; Hemoglobins; Humans; Isoenzymes; Occupational Exposure; Polymorphism, Genetic; Valine

2001
Hemoglobin adducts of ethylene oxide, propylene oxide, acrylonitrile and acrylamide-biomarkers in occupational and environmental medicine.
    Toxicology letters, 2002, Aug-05, Volume: 134, Issue:1-3

    Topics: Acrylamide; Acrylonitrile; Adult; Biomarkers; Diet; Epoxy Compounds; Ethylene Oxide; Gas Chromatography-Mass Spectrometry; Hemoglobins; Humans; Middle Aged; Occupational Exposure; Smoking; Valine

2002
Physiologically based pharmacokinetic model parameter estimation and sensitivity and variability analyses for acrylonitrile disposition in humans.
    Toxicological sciences : an official journal of the Society of Toxicology, 2003, Volume: 71, Issue:1

    Topics: Acrylonitrile; Administration, Inhalation; Administration, Oral; Animals; Area Under Curve; Carcinogens; Drinking; Ethylene Oxide; Female; Genetic Variation; Humans; In Vitro Techniques; Inhalation Exposure; Male; Models, Biological; Rats; Sensitivity and Specificity

2003
Cleaner production and methodological proposal of eco-efficiency measurement in a Mexican petrochemical complex.
    Water science and technology : a journal of the International Association on Water Pollution Research, 2006, Volume: 53, Issue:11

    Topics: Acetaldehyde; Acrylonitrile; Chemical Industry; Ecology; Energy-Generating Resources; Environmental Monitoring; Environmental Pollution; Ethylene Oxide; Ethylenes; Glycols; Mexico; Polyethylene; Polypropylenes; Water Purification

2006
Characterization of the chronic risk and hazard of hazardous air pollutants in the United States using ambient monitoring data.
    Environmental health perspectives, 2009, Volume: 117, Issue:5

    Topics: Acetaldehyde; Acrylonitrile; Air; Air Pollutants; Arsenic; Benzene; Butadienes; Carbon Tetrachloride; Chlorobenzenes; Environmental Monitoring; Ethylene Oxide; Risk Assessment; United States

2009
Simultaneous quantification of haemoglobin adducts of ethylene oxide, propylene oxide, acrylonitrile, acrylamide and glycidamide in human blood by isotope-dilution GC/NCI-MS/MS.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010, Oct-01, Volume: 878, Issue:27

    Topics: Acrylamide; Acrylonitrile; Calibration; Environmental Exposure; Epoxy Compounds; Ethylene Oxide; Gas Chromatography-Mass Spectrometry; Hemoglobins; Humans; Limit of Detection; Pilot Projects; Reference Standards; Reproducibility of Results; Tandem Mass Spectrometry

2010
Accurate quantification of the mercapturic acids of acrylonitrile and its genotoxic metabolite cyanoethylene-epoxide in human urine by isotope-dilution LC-ESI/MS/MS.
    Talanta, 2012, Aug-30, Volume: 98

    Topics: Acetylcysteine; Acrylonitrile; Adult; Aged; Chromatography, Liquid; Ethylene Oxide; Female; Humans; Indicator Dilution Techniques; Limit of Detection; Male; Middle Aged; Occupational Exposure; Smoking; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2012
Nucleic Bases Alkylation with Acrylonitrile and Cyanoethylene Oxide: A Computational Study.
    Chemical research in toxicology, 2018, 02-19, Volume: 31, Issue:2

    Topics: Acrylonitrile; Adenine; Alkylation; Cytosine; Density Functional Theory; Ethylene Oxide; Guanine; Kinetics; Nucleic Acid Conformation; Thymine

2018