Page last updated: 2024-08-17

ethylene oxide and 2-cyanoethylene oxide

ethylene oxide has been researched along with 2-cyanoethylene oxide in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19908 (27.59)18.7374
1990's15 (51.72)18.2507
2000's2 (6.90)29.6817
2010's3 (10.34)24.3611
2020's1 (3.45)2.80

Authors

AuthorsStudies
Wong, JL; Yuan, B1
Kedderis, GL; Rickert, DE; Roberts, AE; Swenberg, JA; Turner, MJ1
Cochrane, J; Liber, H; Recio, L; Simpson, D; Skopek, TR1
Guengerich, FP; Hogy, LL1
Segal, A; Solomon, JJ1
Boreiko, CJ; Kodama, Y; Recio, L; Skopek, TR1
Recio, L; Skopek, TR1
Linhart, I; Novák, J; Smejkal, J1
Geiger, LE; Guengerich, FP; Hogy, LL; Wright, PL1
Appel, KE; Bolt, HM; Mathiasch, B; Peter, H; Schwarz, M1
Holecek, V; Kopecký, J1
Batra, R; Kedderis, GL; Turner, MJ1
Andersen, ME; Batra, R; Fennell, TR; Gargas, ML; Kedderis, GL; Teo, SK1
Batra, R; Kedderis, GL; Kim, SG; Novak, RF1
Gargas, ML; Kedderis, GL; Teo, SK1
Fennell, TR; Recio, L; Sumner, SC; Turner, MJ; Yates, JM1
Fennell, TR; Recio, L; Summer, SC; Turner, MJ; Yates, JM1
Batra, R; Held, SD; Kedderis, GL; Loos, MA; Teo, SK1
Segal, A; Singh, US; Solomon, JJ1
Batra, R; Kedderis, GL1
Batra, R; Fennell, TR; Held, SD; Kedderis, GL; Roberts, AE; Sumner, SC; Turner, MJ1
Batra, R; Gargas, ML; Held, SD; Kedderis, GL; Teo, SK1
Gargas, ML; Hays, SM; Kedderis, GL; Kirman, CR; Strother, DE1
Arrhenius, G; Bauder, A; Dickens, JE; Eschenmoser, A; Irvine, WM; Muller, F; Ohishi, M; Pitsch, S1
Gargas, ML; Kedderis, GL; Strother, DE; Sweeney, LM1
Li, Y; Tan, W; Xue, J; Zhang, X; Zhu, B; Zhu, Z1
Bertram, J; Kraus, T; Schettgen, T1
Bren, U; Gladovic, M; Spaninger, E1
Bren, U; Furlan, V1

Other Studies

29 other study(ies) available for ethylene oxide and 2-cyanoethylene oxide

ArticleYear
Inactivity of acrylonitrile epoxide to modify a Ha-ras DNA in a non-focus transfection-transformation assay.
    Carcinogenesis, 1991, Volume: 12, Issue:5

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Blotting, Southern; Carcinogens; Cell Line; Cell Transformation, Neoplastic; DNA; Ethylene Oxide; Genes, ras; Humans; Methylnitrosourea; Plasmids; Proto-Oncogene Mas; Transfection; Transformation, Genetic

1991
Species comparison of acrylonitrile epoxidation by microsomes from mice, rats and humans: relationship to epoxide concentrations in mouse and rat blood.
    Carcinogenesis, 1991, Volume: 12, Issue:3

    Topics: Acrylonitrile; Animals; Carcinogens; Dose-Response Relationship, Drug; Epoxy Compounds; Ethylene Oxide; Humans; Kinetics; Lung; Male; Mice; Mice, Inbred Strains; Microsomes; Microsomes, Liver; Oxidation-Reduction; Rats; Rats, Inbred F344; Species Specificity

1991
Molecular analysis of hprt mutants induced by 2-cyanoethylene oxide in human lymphoblastoid cells.
    Mutation research, 1990, Volume: 242, Issue:3

    Topics: Base Composition; Base Sequence; Blotting, Southern; Carcinogens; Cell Line; Chromosome Deletion; Cloning, Molecular; Ethylene Oxide; Exons; Humans; Hypoxanthine Phosphoribosyltransferase; Molecular Sequence Data; Mutagenicity Tests; Mutation; Polymerase Chain Reaction

1990
In vivo interaction of acrylonitrile and 2-cyanoethylene oxide with DNA in rats.
    Cancer research, 1986, Volume: 46, Issue:8

    Topics: Acrylonitrile; Alkylation; Animals; DNA; DNA Repair; DNA Replication; Ethylene Oxide; Liver; Male; Mutagens; Nitriles; Perfusion; Rats; Rats, Inbred F344; RNA

1986
DNA adducts of propylene oxide and acrylonitrile epoxide: hydrolytic deamination of 3-alkyl-dCyd to 3-alkyl-dUrd.
    Environmental health perspectives, 1989, Volume: 81

    Topics: Acrylonitrile; Animals; Carcinogens; Cattle; Chemical Phenomena; Chemistry; Deamination; Deoxycytidine; Deoxyuridine; DNA; Epoxy Compounds; Ethers, Cyclic; Ethylene Oxide; Hydrogen-Ion Concentration; Nitriles

1989
Cytogenetic analysis of spontaneous and 2-cyanoethylene oxide-induced tk-/- mutants in TK6 human lymphoblastoid cultures.
    Environmental and molecular mutagenesis, 1989, Volume: 14, Issue:3

    Topics: Cell Division; Cell Line; Chromosome Aberrations; Ethylene Oxide; Humans; Karyotyping; Mutation; Phenotype; Thymidine Kinase

1989
Mutagenicity of acrylonitrile and its metabolite 2-cyanoethylene oxide in human lymphoblasts in vitro.
    Mutation research, 1988, Volume: 206, Issue:2

    Topics: Acrylonitrile; Animals; Biotransformation; Cells, Cultured; Ethylene Oxide; Genetic Markers; Humans; Lymphocytes; Male; Microsomes, Liver; Mutagenicity Tests; Mutagens; Nitriles; Rats; Rats, Inbred Strains; Thymidine Kinase

1988
N-acetyl-S-(1-cyano-2-hydroxyethyl)-L-cysteine, a new urinary metabolite of acrylonitrile and oxiranecarbonitrile.
    Archives of toxicology, 1988, Volume: 61, Issue:6

    Topics: Acetylcysteine; Acrylonitrile; Animals; Biotransformation; Ethylene Oxide; Female; Nitriles; Rats; Rats, Inbred Strains; Stereoisomerism; Thiazines

1988
In vitro metabolism of acrylonitrile to 2-cyanoethylene oxide, reaction with glutathione, and irreversible binding to proteins and nucleic acids.
    Cancer research, 1981, Volume: 41, Issue:12 Pt 1

    Topics: Acrylonitrile; Animals; Biotransformation; DNA; Ethylene Oxide; Glutathione; Hydrogen Cyanide; Inactivation, Metabolic; Male; Microsomes, Liver; Mixed Function Oxygenases; Nitriles; Protein Binding; Rats

1981
A note on synthesis and reactivity towards DNA of glycidonitrile, the epoxide of acrylonitrile.
    Carcinogenesis, 1983, Volume: 4, Issue:2

    Topics: Acrylonitrile; DNA Replication; DNA, Viral; Epoxy Compounds; Ethylene Oxide; Magnetic Resonance Spectroscopy; Nitriles; Simian virus 40; Structure-Activity Relationship

1983
Conjugations of acrylonitrile and glycidonitrile with glutathione--a contribution to problems of metabolism of acrylonitrile.
    Czechoslovak medicine, 1983, Volume: 6, Issue:2

    Topics: Acrylonitrile; Animals; Chemical Phenomena; Chemistry; Ethylene Oxide; Glutathione; Guinea Pigs; Humans; In Vitro Techniques; Liver; Mice; Nitriles; Rabbits; Rats

1983
Conjugation of acrylonitrile and 2-cyanoethylene oxide with hepatic glutathione.
    Toxicology and applied pharmacology, 1995, Volume: 135, Issue:1

    Topics: Acrylonitrile; Animals; Carcinogens; Cytosol; Ethylene Oxide; Glutathione; Humans; Mice; Microsomes, Liver; Rats; Rats, Inbred F344; Subcellular Fractions

1995
A physiologically based dosimetry description of acrylonitrile and cyanoethylene oxide in the rat.
    Toxicology and applied pharmacology, 1995, Volume: 134, Issue:2

    Topics: Acrylonitrile; Animals; Carcinogens; Dose-Response Relationship, Drug; Ethylene Oxide; Glutathione; Male; Rats; Rats, Inbred F344

1995
Induction of rat liver microsomal epoxide hydrolase by thiazole and pyrazine: hydrolysis of 2-cyanoethylene oxide.
    Carcinogenesis, 1993, Volume: 14, Issue:8

    Topics: Animals; Base Sequence; Carcinogens; DNA; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Epoxide Hydrolases; Ethylene Oxide; Gene Amplification; Hydrolysis; Kinetics; Male; Microsomes, Liver; Molecular Sequence Data; Nucleic Acid Hybridization; Polymerase Chain Reaction; Pyrazines; Rats; Rats, Sprague-Dawley; RNA; RNA, Messenger; Sodium Dodecyl Sulfate; Thiazoles

1993
Determination of tissue partition coefficients for volatile tissue-reactive chemicals: acrylonitrile and its metabolite 2-cyanoethylene oxide.
    Toxicology and applied pharmacology, 1994, Volume: 128, Issue:1

    Topics: Acrylonitrile; Animals; Carcinogens; Ethylene Oxide; Liver; Male; Models, Biological; Rats; Rats, Inbred F344; Solubility; Tissue Distribution

1994
Characterization of phosphodiester adducts produced by the reaction of cyanoethylene oxide with nucleotides.
    Carcinogenesis, 1994, Volume: 15, Issue:2

    Topics: Chromatography, High Pressure Liquid; DNA; Esters; Ethylene Oxide; Magnetic Resonance Spectroscopy; Mutagens; Nucleotides; Plasmids; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Ultraviolet

1994
Characterization of an adduct and its degradation product produced by the reaction of cyanoethylene oxide with deoxythymidine and DNA.
    Carcinogenesis, 1993, Volume: 14, Issue:7

    Topics: Animals; Cattle; Chromatography, High Pressure Liquid; DNA; DNA Damage; Ethylene Oxide; Magnetic Resonance Spectroscopy; Mutagens; Spectrometry, Mass, Fast Atom Bombardment; Thymidine

1993
Rodent tissue distribution of 2-cyanoethylene oxide, the epoxide metabolite of acrylonitrile.
    Toxicology letters, 1993, Volume: 69, Issue:1

    Topics: Acrylonitrile; Administration, Oral; Animals; Brain Chemistry; Carcinogens; Ethylene Oxide; Male; Mice; Rats; Rats, Inbred F344; Species Specificity; Tissue Distribution

1993
In vitro reactions of 2-cyanoethylene oxide with calf thymus DNA.
    Chemico-biological interactions, 1993, Volume: 88, Issue:2-3

    Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Chromatography, Paper; Deoxyribonucleosides; DNA; Ethylene Oxide; In Vitro Techniques; Magnetic Resonance Spectroscopy; Mass Spectrometry; Thymus Gland

1993
Species differences in the hydrolysis of 2-cyanoethylene oxide, the epoxide metabolite of acrylonitrile.
    Carcinogenesis, 1993, Volume: 14, Issue:4

    Topics: Animals; Carcinogens; Chromatography, High Pressure Liquid; Enzyme Induction; Epoxide Hydrolases; Ethylene Oxide; Hydrolysis; Male; Mice; Microsomes, Liver; Rats; Rats, Inbred F344; Species Specificity

1993
Dose-dependent urinary excretion of acrylonitrile metabolites by rats and mice.
    Toxicology and applied pharmacology, 1993, Volume: 120, Issue:2

    Topics: Acrylonitrile; Administration, Oral; Animals; Carcinogens; Chromatography, High Pressure Liquid; Ethylene Oxide; Male; Mice; Rats; Rats, Inbred F344; Species Specificity

1993
Refinement and verification of the physiologically based dosimetry description for acrylonitrile in rats.
    Toxicology and applied pharmacology, 1996, Volume: 140, Issue:2

    Topics: Acrylonitrile; Administration, Inhalation; Administration, Oral; Animals; Brain Chemistry; Dose-Response Relationship, Drug; Ethylene Oxide; Injections, Intravenous; Kinetics; Liver; Male; Organ Specificity; Rats; Rats, Inbred F344; Sensitivity and Specificity

1996
Improving cancer dose-response characterization by using physiologically based pharmacokinetic modeling: an analysis of pooled data for acrylonitrile-induced brain tumors to assess cancer potency in the rat.
    Risk analysis : an official publication of the Society for Risk Analysis, 2000, Volume: 20, Issue:1

    Topics: Acrylonitrile; Air Pollutants; Animals; Biological Assay; Brain; Brain Neoplasms; Carcinogens; Databases as Topic; Dose-Response Relationship, Drug; Environmental Exposure; Ethylene Oxide; Forecasting; Guidelines as Topic; Linear Models; Models, Biological; Nonlinear Dynamics; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Risk Assessment; United States; United States Environmental Protection Agency; Water Pollutants, Chemical

2000
A search for interstellar oxiranecarbonitrile (C3H3NO).
    Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 1996, Volume: 26, Issue:2

    Topics: Astronomy; Ethylene Oxide; Evolution, Chemical; Extraterrestrial Environment; Hot Temperature; Organic Chemicals; Origin of Life

1996
Physiologically based pharmacokinetic model parameter estimation and sensitivity and variability analyses for acrylonitrile disposition in humans.
    Toxicological sciences : an official journal of the Society of Toxicology, 2003, Volume: 71, Issue:1

    Topics: Acrylonitrile; Administration, Inhalation; Administration, Oral; Animals; Area Under Curve; Carcinogens; Drinking; Ethylene Oxide; Female; Genetic Variation; Humans; In Vitro Techniques; Inhalation Exposure; Male; Models, Biological; Rats; Sensitivity and Specificity

2003
A simple but highly sensitive and selective colorimetric and fluorescent probe for Cu2+ in aqueous media.
    The Analyst, 2011, Mar-21, Volume: 136, Issue:6

    Topics: Amines; Cations, Divalent; Colorimetry; Copper; Ethylene Oxide; Fluorescent Dyes; Picolinic Acids; Sensitivity and Specificity; Solutions; Spectrophotometry, Atomic; Water; Water Pollutants, Chemical

2011
Accurate quantification of the mercapturic acids of acrylonitrile and its genotoxic metabolite cyanoethylene-epoxide in human urine by isotope-dilution LC-ESI/MS/MS.
    Talanta, 2012, Aug-30, Volume: 98

    Topics: Acetylcysteine; Acrylonitrile; Adult; Aged; Chromatography, Liquid; Ethylene Oxide; Female; Humans; Indicator Dilution Techniques; Limit of Detection; Male; Middle Aged; Occupational Exposure; Smoking; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2012
Nucleic Bases Alkylation with Acrylonitrile and Cyanoethylene Oxide: A Computational Study.
    Chemical research in toxicology, 2018, 02-19, Volume: 31, Issue:2

    Topics: Acrylonitrile; Adenine; Alkylation; Cytosine; Density Functional Theory; Ethylene Oxide; Guanine; Kinetics; Nucleic Acid Conformation; Thymine

2018
Protective Effects of [6]-Gingerol Against Chemical Carcinogens: Mechanistic Insights.
    International journal of molecular sciences, 2020, Jan-21, Volume: 21, Issue:3

    Topics: Aflatoxin B1; Alkylation; Anticarcinogenic Agents; Carcinogens; Catechols; Cell Line; Chemoprevention; Epoxy Compounds; Ethylene Oxide; Fatty Alcohols; Humans; Propiolactone; Urethane; Zingiber officinale

2020