Compounds > ethylene dimethanesulfonate
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ethylene dimethanesulfonate and pregnenolone

ethylene dimethanesulfonate has been researched along with pregnenolone in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hoogerbrugge, JW; Rommerts, FF; Teerds, KJ1
Grootenhuis, AJ; Hoogerbrugge, JW; Rommerts, FF; van der Molen, HJ1
de Rooij, DG; Molenaar, R; Reuvers, PJ; Rommerts, FF; van der Molen, HJ1
de Rooij, DG; Molenaar, R; Rommerts, FF; van der Molen, HJ1
Huhtaniemi, IT; Kero, J; Rannikko, A; Tena-Sempere, M; Zhang, FP1

Other Studies

5 other study(ies) available for ethylene dimethanesulfonate and pregnenolone

ArticleYear
In vitro effects of ethylene-dimethane sulfonate (EDS) on Leydig cells: inhibition of steroid production and cytotoxic effects are dependent on species and age of rat.
    Molecular and cellular endocrinology, 1988, Volume: 55, Issue:1

    Topics: Adenosine Triphosphate; Aging; Alkylating Agents; Animals; Cells, Cultured; Hydroxycholesterols; Leydig Cell Tumor; Leydig Cells; Liver; Luteinizing Hormone; Male; Mesylates; Mice; Pregnenolone; Proteins; Rats; Sertoli Cells; Sexual Maturation; Species Specificity; Testicular Neoplasms; Testis

1988
Ethane dimethane sulphonate (EDS) specifically inhibits LH stimulated steroidogenesis in Leydig cells isolated from mature rats but not in cells from immature rats.
    Molecular and cellular endocrinology, 1985, Volume: 42, Issue:2

    Topics: Alkylating Agents; Animals; Leydig Cells; Luteinizing Hormone; Male; Mesylates; Pregnenolone; Protein Biosynthesis; Rats; Sexual Maturation; Structure-Activity Relationship

1985
Specific destruction of Leydig cells in mature rats after in vivo administration of ethane dimethyl sulfonate.
    Biology of reproduction, 1985, Volume: 33, Issue:5

    Topics: 3-Hydroxysteroid Dehydrogenases; Age Factors; Animals; Busulfan; Cell Survival; Chorionic Gonadotropin; Esterases; Ethyl Methanesulfonate; Leydig Cells; Male; Mesylates; Mice; Pregnenolone; Rats; Testosterone; Time Factors

1985
Repopulation of Leydig cells in mature rats after selective destruction of the existent Leydig cells with ethylene dimethane sulfonate is dependent on luteinizing hormone and not follicle-stimulating hormone.
    Endocrinology, 1986, Volume: 118, Issue:6

    Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Chorionic Gonadotropin; Follicle Stimulating Hormone; Hypophysectomy; Infertility, Male; Kinetics; Leydig Cells; Luteinizing Hormone; Male; Mesylates; Pregnenolone; Rats; Rats, Inbred Strains; Testosterone

1986
Molecular mechanisms of reappearance of luteinizing hormone receptor expression and function in rat testis after selective Leydig cell destruction by ethylene dimethane sulfonate.
    Endocrinology, 1997, Volume: 138, Issue:8

    Topics: Analysis of Variance; Animals; Blotting, Northern; Cell Death; Cyclic AMP; Dose-Response Relationship, Drug; Follicle Stimulating Hormone; Gene Expression Regulation, Developmental; Humans; Leydig Cells; Luteinizing Hormone; Male; Mesylates; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, LH; Recombinant Proteins; RNA, Messenger; Stem Cells; Testis; Testosterone

1997