ethylene chlorohydrin has been researched along with trichloroacetic acid in 72 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (30.56) | 18.7374 |
| 1990's | 22 (30.56) | 18.2507 |
| 2000's | 18 (25.00) | 29.6817 |
| 2010's | 9 (12.50) | 24.3611 |
| 2020's | 1 (1.39) | 2.80 |
| Authors | Studies |
|---|---|
| Escudero, AG; González, MP; Pérez-Garrido, A | 1 |
| Mantel, M; Nothmann, R | 1 |
| Gorczak, J; Krasts, M; Vesterberg, O | 2 |
| Brodersen, R; Onks, DL; Robertson, AF | 1 |
| Deyashiki, Y; Hara, A; Nakayama, T; Oritani, H; Sawada, H; Yamamoto, H | 1 |
| Fujiki, Y; Jyoyama, Y; Michitsuji, H; Ohara, A; Yamaguchi, K | 1 |
| Ekataksin, W; Kawakami, T; Miyazaki, Y; Motohashi, Y; Takano, T | 1 |
| Gorecki, DK; Hall, CA; Hindmarsh, KW; Mayers, DJ; Sankaran, K | 1 |
| Bull, RJ; Larson, JL | 1 |
| Buben, JA; O'Flaherty, EJ | 1 |
| Hobara, T; Iwamoto, S; Kawamoto, T; Kobayashi, H; Sakai, T | 4 |
| Buur, T; Larsson, R; Norlander, B | 1 |
| Hobara, T; Iwamoto, S; Kawamoto, T; Kobayashi, H; Ogino, K; Sakai, T | 1 |
| Hobara, T; Imamura, A; Iwamoto, S; Kawamoto, T; Kobayashi, H; Koshiro, A; Sakai, T | 1 |
| Lowry, LK | 1 |
| Hirota, S; Hobara, T; Iwamoto, S; Kawamoto, T; Kobayashi, H; Sakai, T; Shimazu, W | 1 |
| Carlson, GP; White, JF | 1 |
| Higashihara, E; Hobara, T; Kawamoto, T; Kobayashi, H; Sakai, T | 1 |
| Fujita, H; Ikeda, M; Koizumi, A; Kumai, M; Sadamoto, T; Yamamoto, M | 1 |
| Carlson, GP | 1 |
| Crovato, E; Re, MR | 1 |
| Fu, PP; Kadlubar, FF; Ni, YC | 1 |
| Horiguchi, S; Ikeda, M; Kawai, T; Mizunuma, K | 1 |
| Bonate, PL; Bull, RJ; Stenner, RD; Stevens, DK; Templin, MV; Tuman, D | 1 |
| Bantle, JA; Fort, DJ; Hull, M; Rayburn, JR; Stover, EL | 1 |
| Brodeur, J; Laparé, S; Tardif, R | 1 |
| Bédouin, J; Gaillard, Y; Garnier, R; Pépin, G | 1 |
| Benane, SG; Blackman, CF; House, DE | 1 |
| Casciano, D; Fu, PP; Heinze, TM; Kadlubar, FF; Lloyd, RV; Ni, YC; Shelton, S; Wong, TY | 1 |
| Fukabori, S; Hara, K; Nakaaki, K; Yamamura, Y; Yoshida, K; Yoshida, M; Yuasa, H | 1 |
| Bull, RJ; Merdink, JL; Springer, DL; Stenner, RD; Stevens, DK | 1 |
| Abbas, R; Fisher, JW | 1 |
| Gotoh, M; Hobara, T; Kobayashi, H; Okuda, M | 1 |
| Dawson, BV; Goldberg, SJ; Johnson, PD | 1 |
| Bull, RJ; Gonzalez-Leon, A; Merdink, JL; Schultz, IR | 1 |
| Abbas, R; Fisher, JW; Mahle, D | 1 |
| Burton, GA; Fisher, JW; Greenberg, MS | 1 |
| Henderson, GN; James, MO; Stacpoole, PW; Yan, Z | 1 |
| Blaszkewicz, M; Bolt, HM; Brüning, T; De Smet, K; Rogiers, V; Vercruysse, A | 1 |
| Bloemen, LJ; Commandeur, JN; Kezic, S; Monster, AC; Vermeulen, NP; Veulemans, H; Wilmer, JW | 1 |
| Brüning, T; Fels, LM; Fricke, HH; Mensing, T; Voss, B; Welge, P; Wilhelm, M | 1 |
| Bucci, TJ; Chou, MW; Fu, PP; Kadlubar, FF; Samokyszyn, VM; Von Tungeln, LS; Yi, P | 1 |
| Forkert, PG; Lash, LH; Nadeau, V; Simmonds, A; Tardif, R | 1 |
| Deng, YY; Huang, JX; Li, LY; Tang, XJ | 1 |
| MARSHALL, EK; OWENS, AH | 1 |
| MEDEK, V | 1 |
| BARTONICEK, V | 1 |
| Edwards, RA; Ladner, CL; Turner, RJ; Yang, J | 1 |
| Igisu, H; Narimatsu, H | 1 |
| Dills, RL; Johns, DO; Morgan, MS | 1 |
| Anand, SS; Mehendale, HM; Mumtaz, MM | 1 |
| Ikeda, M; Inoue, O; Ukai, H | 1 |
| Bronley-DeLancey, A; Hoel, DG; Jollow, DJ; McMillan, DC; McMillan, JM; Mohr, LC | 1 |
| Chiu, WA; Clewell, HJ; Hack, CE; Jay Zhao, Q | 1 |
| Lock, EA; McMillan, JM; Oatis, JE; Reed, CJ; Schnellmann, RG | 1 |
| Bartolucci, GB; Carrieri, M; Magosso, D; Piccoli, P; Trevisan, A; Zanetti, E | 1 |
| Bull, RJ; Hu, M; Merdink, JL; Parker, JC; Robison, LM; Stevens, DK | 1 |
| Arndt, T; Gierten, B; Grüner, J; Güssregen, B; Werle, A | 1 |
| Bonvallot, N; Cordier, S; Dananché, B; Garlantézec, R; Labat, L; Monfort, C; Multigner, L; Pulkkinen, J; Rouget, F | 1 |
| Bin, P; Dai, Y; Dong, H; Duan, H; Liu, Q; Niu, Y; Yang, H; Zang, D; Zheng, Y | 1 |
| Evans, AR; Lock, EA; Yaqoob, N | 1 |
| Hibino, Y; Huang, H; Huang, Y; Ito, Y; Jia, X; Kamijima, M; Li, H; Liu, L; Naito, H; Nakajima, T; Song, X; Wang, D; Wang, H; Zhao, N | 1 |
| Ball, LM; Bodnar, WM; Bradford, BU; Collins, LB; Gold, A; Kosyk, O; Rusyn, I; Shymonyak, S; Uehara, T; Yoo, HS | 2 |
| Alexander, K; McAuley, KB; Nasr, AT; Schreiner, LJ | 1 |
| Charest-Tardif, G; Haddad, S; Rouhou, MC | 1 |
| Hashimoto, S; Inoue, M; Ito, Y; Kamijima, M; Nakahira, Y; Nakajima, T; Sato, H | 1 |
| Cai, T; Huang, H; Huang, Y; Ito, Y; Kamijima, M; Li, H; Liu, L; Lu, F; Naito, H; Nakajima, T; Song, X; Wang, H; Zhao, N | 1 |
1 review(s) available for ethylene chlorohydrin and trichloroacetic acid
| Article | Year |
|---|---|
[Trichloroacetic acid and trichloroethanol in urine].
Topics: Biomarkers; Chromatography, Gas; Environmental Exposure; Environmental Monitoring; Ethylene Chlorohydrin; Reference Values; Solvents; Specimen Handling; Tetrachloroethylene; Trichloroacetic Acid; Trichloroethanes; Trichloroethylene | 2004 |
1 trial(s) available for ethylene chlorohydrin and trichloroacetic acid
| Article | Year |
|---|---|
A human physiologically based pharmacokinetic model for trichloroethylene and its metabolites, trichloroacetic acid and free trichloroethanol.
Topics: Administration, Inhalation; Adult; Ethylene Chlorohydrin; Female; Humans; Male; Models, Biological; Sex Factors; Solvents; Time Factors; Tissue Distribution; Trichloroacetic Acid; Trichloroethylene | 1998 |
70 other study(ies) available for ethylene chlorohydrin and trichloroacetic acid
| Article | Year |
|---|---|
Halogenated derivatives QSAR model using spectral moments to predict haloacetic acids (HAA) mutagenicity.
Topics: Acetates; Chloroacetates; Computer Simulation; Data Collection; Hydrocarbons, Brominated; Models, Chemical; Models, Molecular; Mutagenicity Tests; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Reproducibility of Results; Sensitivity and Specificity; Structure-Activity Relationship; Trichloroacetic Acid | 2008 |
Rapid determination of trichloroethanol and trichloroacetic acid in urine.
Topics: Chlorohydrins; Ethylene Chlorohydrin; Methods; Spectrophotometry; Trichloroacetic Acid | 1977 |
Exposure to trichloroethylene II. Metabolites in blood and urine.
Topics: Chlorohydrins; Dose-Response Relationship, Drug; Environmental Exposure; Ethylene Chlorohydrin; Humans; Male; Occupational Medicine; Physical Exertion; Trichloroacetic Acid; Trichloroethylene | 1976 |
Methods for measuring trichloroethanol and trichloroacetic acid in blood and urine after exposure to trichloroethylene.
Topics: Biotransformation; Chlorohydrins; Environmental Exposure; Ethylene Chlorohydrin; Humans; Trichloroacetic Acid; Trichloroethylene | 1975 |
The effect of chloral hydrate and its metabolites, trichloroethanol and trichloroacetic acid, on bilirubin-albumin binding.
Topics: Bilirubin; Chloral Hydrate; Ethylene Chlorohydrin; Humans; Oxidation-Reduction; Protein Binding; Regression Analysis; Serum Albumin; Spectrophotometry, Ultraviolet; Trichloroacetic Acid | 1992 |
Aldehyde dismutation catalyzed by pulmonary carbonyl reductase: kinetic studies of chloral hydrate metabolism to trichloroacetic acid and trichloroethanol.
Topics: Alcohol Oxidoreductases; Aldehydes; Animals; Catalysis; Chloral Hydrate; Ethylene Chlorohydrin; Guinea Pigs; Kinetics; Liver; Lung; Male; Mice; Oxidation-Reduction; Trichloroacetic Acid | 1991 |
[Determination of trichloroacetic acid and trichloroethanol by head-space gas chromatography (HS.GC)].
Topics: Chromatography, Gas; Ethylene Chlorohydrin; Humans; Methods; Reproducibility of Results; Trichloroacetic Acid | 1991 |
Circadian variations in trichloroethylene toxicity under a 12:12 hr light-dark cycle and their alterations under constant darkness in rats.
Topics: Animals; Body Temperature; Body Weight; Circadian Rhythm; Darkness; Ethylene Chlorohydrin; Kidney; Lighting; Liver; Male; Necrosis; Organ Size; Rats; Rats, Inbred Strains; Time Factors; Trichloroacetic Acid; Trichloroethylene | 1990 |
Determination of chloral hydrate metabolism in adult and neonate biological fluids after single-dose administration.
Topics: Adult; Body Fluids; Chloral Hydrate; Chromatography, Gas; Ethylene Chlorohydrin; Humans; Infant; Male; Trichloroacetic Acid | 1990 |
Effect of ethanol on the metabolism of trichloroethylene.
Topics: Animals; Biotransformation; Drug Interactions; Ethanol; Ethylene Chlorohydrin; Male; Rats; Rats, Inbred Strains; Trichloroacetic Acid; Trichloroethylene | 1989 |
Delineation of the role of metabolism in the hepatotoxicity of trichloroethylene and perchloroethylene: a dose-effect study.
Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Ethylene Chlorohydrin; Glucose-6-Phosphatase; Liver Diseases; Male; Mice; Organ Size; Tetrachloroethylene; Trichloroacetic Acid; Trichloroethylene; Triglycerides | 1985 |
The absorption of trichloroethylene and its metabolites from the urinary bladder of anesthetized dogs.
Topics: Animals; Bile; Chloral Hydrate; Dogs; Dose-Response Relationship, Drug; Ethylene Chlorohydrin; Female; Male; Trichloroacetic Acid; Trichloroethylene; Urinary Bladder | 1988 |
Pharmacokinetics of chloral hydrate poisoning treated with hemodialysis and hemoperfusion.
Topics: Adult; Chloral Hydrate; Ethylene Chlorohydrin; Female; Hemoperfusion; Humans; Renal Dialysis; Trichloroacetic Acid | 1988 |
Intestinal absorption of chloral hydrate, free trichloroethanol and trichloroacetic acid in dogs.
Topics: Animals; Chloral Hydrate; Chlorohydrins; Colon; Dogs; Ethylene Chlorohydrin; Female; Ileum; Intestinal Absorption; Jejunum; Male; Trichloroacetic Acid | 1988 |
The cholecystohepatic circulation of trichloroethylene and its metabolites in dogs.
Topics: Absorption; Animals; Bile; Chloral Hydrate; Dogs; Ethylene Chlorohydrin; Female; Gallbladder; Inactivation, Metabolic; Liver; Male; Trichloroacetic Acid; Trichloroethylene | 1987 |
Alteration of chloral hydrate metabolism in rats with carbon tetrachloride-induced liver damage.
Topics: Animals; Bile; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chloral Hydrate; Ethylene Chlorohydrin; Liver Diseases; Male; Metabolic Clearance Rate; Perfusion; Rats; Rats, Inbred Strains; Trichloroacetic Acid | 1987 |
The metabolism of trichloroethylene and its metabolites in the perfused liver.
Topics: Animals; Bile; Chloral Hydrate; Ethylene Chlorohydrin; Liver; Male; Perfusion; Rats; Rats, Inbred Strains; Trichloroacetic Acid; Trichloroethylene | 1987 |
Extrahepatic metabolism of chloral hydrate, trichloroethanol and trichloroacetic acid in dogs.
Topics: Animals; Chloral Hydrate; Chlorohydrins; Dogs; Ethylene Chlorohydrin; Male; Trichloroacetic Acid | 1987 |
The biological exposure index: its use in assessing chemical exposures in the workplace.
Topics: Acetates; Butanones; Environmental Exposure; Environmental Monitoring; Ethylene Chlorohydrin; Ethylene Glycols; Humans; Industry; Maximum Allowable Concentration; National Institute for Occupational Safety and Health, U.S.; Paint; Trichloroacetic Acid; Trichloroethylene; United States | 1987 |
Extrahepatic organs metabolism of inhaled trichloroethylene.
Topics: Administration, Inhalation; Animals; Dogs; Ethylene Chlorohydrin; Female; Leukocyte Count; Liver; Male; Trichloroacetic Acid; Trichloroethylene | 1986 |
Cardiac arrhythmogenic action of benzo(a)pyrene in the rabbit.
Topics: Animals; Arrhythmias, Cardiac; Benzo(a)pyrene; Benzopyrenes; Epinephrine; Ethylene Chlorohydrin; Halothane; Male; Methylcholanthrene; Phenobarbital; Rabbits; Time Factors; Trichloroacetic Acid; Trichloroethylene | 1983 |
[Experimental studies of trichloroethylene toxicity. II. Changes in trichloroethylene metabolites in blood serum and in urine during and after exposure to trichloroethylene].
Topics: Animals; Chlorohydrins; Dogs; Environmental Exposure; Ethylene Chlorohydrin; Trichloroacetic Acid; Trichloroethylene | 1983 |
Inhibition of delta-aminolevulinic acid dehydratase by trichloroethylene.
Topics: 5-Aminolevulinate Synthetase; Animals; Bone Marrow; Erythrocytes; Ethylene Chlorohydrin; In Vitro Techniques; Liver; Male; Phenobarbital; Porphobilinogen Synthase; Rats; Rats, Inbred Strains; Trichloroacetic Acid; Trichloroethanes; Trichloroethylene | 1984 |
Effect of alterations in drug metabolism on epinephrine-induced cardiac arrhythmias in rabbits exposed to methylchloroform.
Topics: Animals; Antimetabolites; Arrhythmias, Cardiac; Biphenyl Compounds; Cytochrome P-450 Enzyme System; Diethylamines; Epinephrine; Ethylene Chlorohydrin; Hydrocarbons, Chlorinated; Male; Phenobarbital; Proadifen; Rabbits; Trichloroacetic Acid; Trichloroethanes | 1981 |
[Percutaneous absorption of trieline with warning levels of the biological indices].
Topics: Air Pollutants, Occupational; Environmental Exposure; Ethylene Chlorohydrin; Humans; Risk; Skin Absorption; Trichloroacetic Acid; Trichloroethylene | 1981 |
Formation of malondialdehyde-modified 2'-deoxyguanosinyl adduct from metabolism of chloral hydrate by mouse liver microsomes.
Topics: Animals; Cattle; Chloral Hydrate; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA; DNA Adducts; Ethylene Chlorohydrin; Isotope Labeling; Lipid Peroxidation; Male; Malondialdehyde; Mice; Microsomes, Liver; Phosphorus Radioisotopes; Trichloroacetic Acid | 1995 |
Urinary methylchloroform rather than urinary metabolites as an indicator of occupational exposure to methylchloroform.
Topics: Chemical Industry; Chromatography, Gas; Colorimetry; Environmental Monitoring; Ethylene Chlorohydrin; Humans; Male; Occupational Exposure; Regression Analysis; Sensitivity and Specificity; Trichloroacetic Acid; Trichloroethanes; Urinalysis | 1995 |
Factors affecting species differences in the kinetics of metabolites of trichloroethylene.
Topics: Adult; Animals; Blood Proteins; Dogs; Ethylene Chlorohydrin; Humans; Male; Protein Binding; Rats; Rats, Inbred F344; Species Specificity; Trichloroacetic Acid; Trichloroethylene | 1995 |
Evaluation of the developmental toxicity of trichloroethylene and detoxification metabolites using Xenopus.
Topics: Animals; Carbon Monoxide; Cyclohexanes; Cyclohexenes; Dichloroacetic Acid; Epoxide Hydrolases; Ethylene Chlorohydrin; In Vitro Techniques; Inactivation, Metabolic; Male; Mixed Function Oxygenases; Oxalates; Oxalic Acid; Rats; Rats, Sprague-Dawley; Teratogens; Trichloroacetic Acid; Trichloroethylene; Xenopus laevis | 1993 |
Effect of various exposure scenarios on the biological monitoring of organic solvents in alveolar air. II. 1,1,1-Trichloroethane and trichloroethylene.
Topics: Adult; Air Pollutants, Occupational; Environmental Monitoring; Ethylene Chlorohydrin; Female; Humans; Male; Middle Aged; Occupational Exposure; Physical Exertion; Pulmonary Alveoli; Solvents; Time Factors; Trichloroacetic Acid; Trichloroethanes; Trichloroethylene | 1995 |
Coin-operated dry cleaning machines may be responsible for acute tetrachloroethylene poisoning: report of 26 cases including one death.
Topics: Adult; Child, Preschool; Ethylene Chlorohydrin; Fatal Outcome; Female; Humans; Laundering; Male; Middle Aged; Poison Control Centers; Poisoning; Retrospective Studies; Tetrachloroethylene; Tissue Distribution; Trichloroacetic Acid | 1996 |
Effect of perchloroethylene and its metabolites on intercellular communication in clone 9 rat liver cells.
Topics: Analysis of Variance; Animals; Chloral Hydrate; Clone Cells; Dichloroacetic Acid; Ethylene Chlorohydrin; Gap Junctions; Liver; Male; Rats; Rats, Sprague-Dawley; Tetrachloroethylene; Trichloroacetic Acid; Water Pollutants | 1996 |
Mouse liver microsomal metabolism of chloral hydrate, trichloroacetic acid, and trichloroethanol leading to induction of lipid peroxidation via a free radical mechanism.
Topics: Allopurinol; Animals; Catalysis; Cell Line; Chloral Hydrate; Ethylene Chlorohydrin; Free Radicals; Gas Chromatography-Mass Spectrometry; Horseradish Peroxidase; Humans; Lipid Peroxidation; Male; Mice; Microsomes, Liver; NAD; NADP; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Trichloroacetic Acid; Xanthine Oxidase | 1996 |
Concentrations of trichloroethylene and its metabolites in blood and urine after acute poisoning by ingestion.
Topics: Accidents, Home; Administration, Oral; Ethylene Chlorohydrin; Humans; Male; Middle Aged; Trichloroacetic Acid; Trichloroethylene | 1996 |
Enterohepatic recirculation of trichloroethanol glucuronide as a significant source of trichloroacetic acid. Metabolites of trichloroethylene.
Topics: Animals; Bile; Chromatography, Gas; Enterohepatic Circulation; Ethylene Chlorohydrin; Glucuronates; Male; Rats; Rats, Inbred F344; Trichloroacetic Acid; Trichloroethylene | 1997 |
A physiologically based pharmacokinetic model for trichloroethylene and its metabolites, chloral hydrate, trichloroacetate, dichloroacetate, trichloroethanol, and trichloroethanol glucuronide in B6C3F1 mice.
Topics: Administration, Oral; Animals; Chloral Hydrate; Dichloroacetic Acid; Ethylene Chlorohydrin; Feces; Glucuronates; Liver; Male; Mice; Mice, Inbred Strains; Models, Biological; Solvents; Tissue Distribution; Trichloroacetic Acid; Trichloroethylene | 1997 |
Pollution due to trichloroacetic acid in clams (Tapes japonica) in an estuary adjacent to industrial areas.
Topics: Animals; Bivalvia; Environmental Monitoring; Ethylene Chlorohydrin; Industry; Japan; Seawater; Shellfish; Trichloroacetic Acid; Volatilization; Water Pollutants, Chemical | 1998 |
Cardiac teratogenicity of trichloroethylene metabolites.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Acetates; Animals; Chloral Hydrate; Cystine; Dichloroethylenes; Embryonic and Fetal Development; Environmental Pollutants; Ethylene Chlorohydrin; Female; Heart; Heart Defects, Congenital; Humans; Maternal Exposure; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Teratogens; Trichloroacetic Acid; Trichloroethylene; Water Pollutants, Chemical; Water Supply | 1998 |
The extent of dichloroacetate formation from trichloroethylene, chloral hydrate, trichloroacetate, and trichloroethanol in B6C3F1 mice.
Topics: Animals; Biological Availability; Chloral Hydrate; Dichloroacetic Acid; Ethylene Chlorohydrin; Half-Life; Male; Metabolic Clearance Rate; Mice; Models, Biological; Trichloroacetic Acid; Trichloroethylene | 1998 |
Physiologically based pharmacokinetic modeling of inhaled trichloroethylene and its oxidative metabolites in B6C3F1 mice.
Topics: Adipose Tissue; Administration, Inhalation; Animals; Chloral Hydrate; Dichloroacetic Acid; Ethylene Chlorohydrin; Kidney; Liver; Lung; Male; Metabolic Clearance Rate; Mice; Mice, Inbred Strains; Models, Biological; Oxidation-Reduction; Sensitivity and Specificity; Solvents; Tissue Distribution; Trichloroacetic Acid; Trichloroethylene | 1999 |
Determination of chloral hydrate metabolites in human plasma by gas chromatography-mass spectrometry.
Topics: Acetals; Acetates; Acidosis, Lactic; Administration, Oral; Child; Chloral Hydrate; Dichloroacetic Acid; Ethylene Chlorohydrin; Evaluation Studies as Topic; Gas Chromatography-Mass Spectrometry; Glucuronates; Glucuronides; Humans; Hydroxamic Acids; Reproducibility of Results; Sensitivity and Specificity; Trichloroacetic Acid | 1999 |
Biotransformation of trichloroethylene in collagen gel sandwich cultures of rat hepatocytes.
Topics: Animals; Animals, Outbred Strains; Biotransformation; Cells, Cultured; Chromatography, Gas; Collagen; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP2E1; Ethylene Chlorohydrin; Extracellular Matrix; Hepatocytes; Male; Models, Biological; Rats; Rats, Sprague-Dawley; Trichloroacetic Acid; Trichloroethylene | 2000 |
Study on the cytochrome P-450- and glutathione-dependent biotransformation of trichloroethylene in humans.
Topics: Adult; Air Pollutants, Occupational; Biomarkers; Biotransformation; Cytochrome P-450 Enzyme System; Ethylene Chlorohydrin; Glutathione; Humans; Male; Middle Aged; Occupational Exposure; Trichloroacetic Acid; Trichloroethylene | 2001 |
Renal toxicity after chronic inhalation exposure of rats to trichloroethylene.
Topics: Acetylglucosaminidase; Albuminuria; Animals; Comet Assay; DNA Fragmentation; Ethylene Chlorohydrin; Histocytochemistry; Inhalation Exposure; Kidney Diseases; Male; Rats; Rats, Long-Evans; Trichloroacetic Acid; Trichloroethylene | 2002 |
Tumorigenicity of chloral hydrate, trichloroacetic acid, trichloroethanol, malondialdehyde, 4-hydroxy-2-nonenal, crotonaldehyde, and acrolein in the B6C3F(1) neonatal mouse.
Topics: Acrolein; Aldehydes; Animals; Animals, Newborn; Carcinogenicity Tests; Carcinogens; Chloral Hydrate; Chromatography, High Pressure Liquid; Crosses, Genetic; DNA; DNA Adducts; Electrochemistry; Ethylene Chlorohydrin; Female; Lipid Peroxidation; Liver; Liver Neoplasms, Experimental; Male; Malondialdehyde; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Microsomes, Liver; Phosphorus Radioisotopes; Trichloroacetic Acid | 2002 |
Metabolism and toxicity of trichloroethylene in epididymis and testis.
Topics: Administration, Inhalation; Animals; Blotting, Western; Chloral Hydrate; Cytochrome P-450 CYP2E1; Epididymis; Ethylene Chlorohydrin; Immunohistochemistry; Male; Mice; Microsomes; Occupational Exposure; Testis; Trichloroacetic Acid; Trichloroethylene | 2002 |
Guinea pig maximization test for trichloroethylene and its metabolites.
Topics: Allergens; Animals; Chloral Hydrate; Dermatitis, Allergic Contact; Dermatitis, Irritant; Ethylene Chlorohydrin; Guinea Pigs; Skin; Toxicity Tests; Trichloroacetic Acid; Trichloroethylene | 2002 |
Further studies on the metabolic fate of chloral hydrate and trichloroethanol.
Topics: Biochemical Phenomena; Blood; Chloral Hydrate; Ethanol; Ethylene Chlorohydrin; Humans; Trichloroacetic Acid; Trichloroethylene | 1955 |
[Relation between the content of trichloroethanol and trichloroacetic acid in the urine and the trichloroethylene content of the atmosphere, as determined by field work].
Topics: Atmosphere; Ethanol; Ethylene Chlorohydrin; Humans; Trichloroacetic Acid; Trichloroethylene | 1958 |
[The effect of various substances on urinary excretion of trichlorethanol and trichloroacetic acid in the rabbit].
Topics: Animals; Ethanol; Ethylene Chlorohydrin; Rabbits; Trichloroacetic Acid | 1960 |
Visible fluorescent detection of proteins in polyacrylamide gels without staining.
Topics: Acrylic Resins; Electrophoresis, Gel, Two-Dimensional; Ethylene Chlorohydrin; Fluorescence; Proteins; Rosaniline Dyes; Staining and Labeling; Trichloroacetic Acid | 2004 |
Evaluation of dynamic headspace with gas chromatography/mass spectrometry for the determination of 1,1,1-trichloroethane, trichloroethanol, and trichloroacetic acid in biological samples.
Topics: Ethylene Chlorohydrin; Gas Chromatography-Mass Spectrometry; Humans; Trichloroacetic Acid; Trichloroethanes | 2005 |
Dose-dependent liver regeneration in chloroform, trichloroethylene and allyl alcohol ternary mixture hepatotoxicity in rats.
Topics: Administration, Oral; Animals; Chloroform; D-Alanine Transaminase; Drug Interactions; Ethylene Chlorohydrin; Injections, Intraperitoneal; Liver; Liver Regeneration; Male; Propanols; Rats; Rats, Sprague-Dawley; Trichloroacetic Acid; Trichloroethylene | 2005 |
Green chemistry in urinalysis for trichloroethanol and trichloroacetic acid as markers of exposure to chlorinated hydrocarbon solvents.
Topics: Biomarkers; Ethylene Chlorohydrin; Female; Humans; Hydrocarbons, Chlorinated; Male; Occupational Exposure; Solvents; Trichloroacetic Acid | 2006 |
Application of cryopreserved human hepatocytes in trichloroethylene risk assessment: relative disposition of chloral hydrate to trichloroacetate and trichloroethanol.
Topics: Adult; Aged; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Animals; Chloral Hydrate; Cryopreservation; Ethylene Chlorohydrin; Female; Genotype; Hepatocytes; Humans; In Vitro Techniques; Kinetics; Male; Middle Aged; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Risk Assessment; Solvents; Trichloroacetic Acid; Trichloroethylene | 2006 |
Bayesian population analysis of a harmonized physiologically based pharmacokinetic model of trichloroethylene and its metabolites.
Topics: Animals; Bayes Theorem; Chloral Hydrate; Dichloroacetic Acid; Dose-Response Relationship, Drug; Ethylene Chlorohydrin; Humans; Kinetics; Markov Chains; Mice; Models, Biological; Monte Carlo Method; Rats; Sulfhydryl Compounds; Trichloroacetic Acid; Trichloroethylene | 2006 |
Lack of formic acid production in rat hepatocytes and human renal proximal tubule cells exposed to chloral hydrate or trichloroacetic acid.
Topics: Adolescent; Adult; Animals; Chemical and Drug Induced Liver Injury; Chloral Hydrate; Chromatography, Gas; Ethylene Chlorohydrin; Formates; Hepatocytes; Humans; Kidney Diseases; Kidney Tubules, Proximal; Liver Diseases; Magnetic Resonance Spectroscopy; Male; Rats; Trichloroacetic Acid | 2007 |
Acute, nonfatal intoxication with trichloroethylene.
Topics: Acetylglucosaminidase; Acute Disease; Biomarkers; Ethylene Chlorohydrin; Glutamate-Ammonia Ligase; Humans; Inhalation Exposure; Kidney Diseases; Male; Middle Aged; Occupational Diseases; Proteinuria; Solvents; Trichloroacetic Acid; Trichloroethylene | 2007 |
Kinetics of chloral hydrate and its metabolites in male human volunteers.
Topics: Adult; Chloral Hydrate; Dichloroacetic Acid; Ethylene Chlorohydrin; Glucuronates; Humans; Liver; Male; Middle Aged; Time Factors; Trichloroacetic Acid | 2008 |
False-positive ethyl glucuronide immunoassay screening associated with chloral hydrate medication as confirmed by LC-MS/MS and self-medication.
Topics: Adult; Biomarkers; Chloral Hydrate; Chromatography, Liquid; Cross Reactions; Ethylene Chlorohydrin; False Positive Reactions; Female; Forensic Toxicology; Glucuronates; Humans; Hypnotics and Sedatives; Immunoassay; Mass Spectrometry; Self Medication; Trichloroacetic Acid | 2009 |
Urinary biomarkers of exposure to glycol ethers and chlorinated solvents during pregnancy: determinants of exposure and comparison with indirect methods of exposure assessment.
Topics: Adult; Biomarkers; Carboxylic Acids; Cohort Studies; Ethylene Chlorohydrin; Female; Humans; Maternal Exposure; Occupational Exposure; Pregnancy; Solvents; Surveys and Questionnaires; Trichloroacetic Acid | 2012 |
Trichloroethanol up-regulates matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in HaCaT cells.
Topics: Air Pollutants, Occupational; Cell Line; Cell Survival; Ethylene Chlorohydrin; Humans; Hypersensitivity; Keratinocytes; Matrix Metalloproteinase 9; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Trichloroacetic Acid; Trichloroethylene; Up-Regulation | 2011 |
Trichloroethylene-induced formic aciduria: effect of dose, sex and strain of rat.
Topics: Animals; Cytochrome P-450 CYP2E1; Dose-Response Relationship, Drug; Enzyme Induction; Ethylene Chlorohydrin; Female; Formates; Kidney; Male; Rats; Rats, Inbred F344; Rats, Wistar; Sex Factors; Solvents; Species Specificity; Time Factors; Trichloroacetic Acid; Trichloroethylene | 2013 |
Sex differences in metabolism of trichloroethylene and trichloroethanol in guinea pigs.
Topics: Allergens; Animals; Dermatitis, Allergic Contact; Ethylene Chlorohydrin; Female; Gas Chromatography-Mass Spectrometry; Guinea Pigs; Injections, Intramuscular; Male; Trichloroacetic Acid; Trichloroethylene | 2013 |
Comparative analysis of the relationship between trichloroethylene metabolism and tissue-specific toxicity among inbred mouse strains: liver effects.
Topics: Administration, Oral; Animals; Carcinogens; Cell Proliferation; Cysteine; Cytochrome P-450 Enzyme System; Dichloroacetic Acid; Dose-Response Relationship, Drug; Ethylene Chlorohydrin; Gene Expression; Glutathione; Hepatocytes; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Oxidation-Reduction; Oxidative Stress; Real-Time Polymerase Chain Reaction; Solvents; Trichloroacetic Acid; Trichloroethylene | 2015 |
Comparative analysis of the relationship between trichloroethylene metabolism and tissue-specific toxicity among inbred mouse strains: kidney effects.
Topics: Animals; Carcinogens; Cell Proliferation; Cysteine; Cytochrome P-450 Enzyme System; Dichloroacetic Acid; Ethylene Chlorohydrin; Glutathione; Hepatitis A Virus Cellular Receptor 1; Kidney; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Oxidation-Reduction; PPAR alpha; Trichloroacetic Acid; Trichloroethylene | 2015 |
Leuco-crystal-violet micelle gel dosimeters: I. Influence of recipe components and potential sensitizers.
Topics: Cetrimonium; Cetrimonium Compounds; Dose-Response Relationship, Radiation; Ethylene Chlorohydrin; Gels; Gentian Violet; Hydrogen-Ion Concentration; Micelles; Octoxynol; Radiometry; Rosaniline Dyes; Surface-Active Agents; Trichloroacetic Acid | 2015 |
In vivo effects of naproxen, salicylic acid, and valproic acid on the pharmacokinetics of trichloroethylene and metabolites in rats.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Ethylene Chlorohydrin; Male; Models, Theoretical; Naproxen; Rats; Rats, Sprague-Dawley; Risk Assessment; Salicylic Acid; Solvents; Trichloroacetic Acid; Trichloroethylene; Valproic Acid | 2015 |
Simple method to detect triclofos and its metabolites in plasma of children by combined use of liquid chromatography tandem-mass spectrometry and gas chromatography-mass spectrometry.
Topics: Child, Preschool; Chloral Hydrate; Chromatography, Liquid; Ethylene Chlorohydrin; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydrolysis; Hypnotics and Sedatives; Infant; Japan; Limit of Detection; Male; Mass Spectrometry; Organophosphates; Reproducibility of Results; Tandem Mass Spectrometry; Trichloroacetic Acid | 2019 |
Trichloroethylene and trichloroethanol induce skin sensitization with focal hepatic necrosis in guinea pigs.
Topics: Animals; Chemical and Drug Induced Liver Injury; Ethylene Chlorohydrin; Female; Guinea Pigs; Hypersensitivity; Necrosis; Occupational Exposure; Skin Diseases; Trichloroacetic Acid; Trichloroethylene | 2020 |