ethyl methanesulfonate has been researched along with thioguanine anhydrous in 44 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (68.18) | 18.7374 |
| 1990's | 13 (29.55) | 18.2507 |
| 2000's | 1 (2.27) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Coffino, P; Friedrich, U | 1 |
| Brimer, PA; Gosslee, DG; Hsie, AW; Mitchell, TJ | 1 |
| Brimmer, PA; Hsie, AW; Hsie, MH; Machanoff, R | 1 |
| Arlett, CF; Cole, J | 2 |
| Hsie, AW; O'Neill, JP | 1 |
| Henderson, JF; Lomax, CA | 1 |
| Sekiguchi, F; Sekiguchi, T; Tomii, S | 1 |
| Knaap, AG; Simons, JW | 1 |
| Mirzayans, F; Mirzayans, R; Parry, JM | 1 |
| Kuroda, Y; Tamai, K; Tezuka, H | 1 |
| Jansson, K; Jansson, V | 1 |
| Ferguson, LR; Hill, CL; Morecombe, P | 1 |
| Boyes, BG; Rogers, CG; Stapley, R | 1 |
| Boyes, BG; Karpinsky, K; Rogers, CG; Stapley, R | 1 |
| Arlett, CF; Masters, JR; Parris, CN; Walker, MC | 1 |
| Ivarie, R; Morris, JA | 1 |
| Kreipe, H; Parwaresch, MR; Radzun, HJ | 1 |
| Koizumi, A; Kuroda, Y; Morimoto, K; Tachi-Shinkawa, K | 1 |
| Yamashina, K | 1 |
| Bradley, WE; Laviolette, F | 1 |
| Heppner, GH; Yamashina, K | 1 |
| Gupta, RS; Siminovitch, L; Srinivasan, PR | 1 |
| Bauer, E; Cefalu, W; Frost, P; Kerbel, RS; Tartamella-Biondo, R | 1 |
| Evans, HJ | 1 |
| Adair, GM; Carver, JH; Wandres, DL | 1 |
| Sakaguchi, K; Sono, A | 2 |
| Brown, R; Thacker, J | 1 |
| Kaina, B | 1 |
| Colella, CM; Piras, A; Rainaldi, G | 1 |
| Hsie, AW; Machanoff, R; O'Neill, JP | 1 |
| Boyle, JM; Durrant, L; Fox, M; McMillan, S | 1 |
| Morry, DW; Ts'o, PO | 1 |
| Meyers, MB; Shin, S; van Diggelen, M; van Diggelen, OP | 1 |
| Balint, RF; Levine, AJ; Rosenstraus, MJ | 1 |
| Jansen, JG; Mohn, GR; Tates, AD; van Teijlingen, CM; van Zeeland, AA; Vrieling, H | 1 |
| Hoff, E; Klungland, A; Laake, K; Seeberg, E | 1 |
| Blickensderfer, DB; Branda, RF | 1 |
| Branda, RF; Lafayette, AR; Nicklas, JA; O'Neill, JP | 2 |
| Anderson, D; Plewa, MJ; Rayburn, AL; Wagner, ED | 1 |
| Kaji, K; Kuroda, Y; Shima, N; Yazawa, K | 1 |
| Fox, M; Hodgkiss, RJ | 1 |
44 other study(ies) available for ethyl methanesulfonate and thioguanine anhydrous
| Article | Year |
|---|---|
Mutagenesis in S49 mouse lymphoma cells: induction of resistance to ouabain, 6-thioguanine, and dibutyryl cyclic AMP.
Topics: Bucladesine; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance; Ethyl Methanesulfonate; Kinetics; Lymphoma; Methylnitronitrosoguanidine; Mutagens; Mutation; Ouabain; Thioguanine | 1977 |
The dose-response relationship for ethyl methanesulfonate-induced mutations at the hypoxanthine-guanine phosphoribosyl transferase locus in Chinese hamster ovary cells.
Topics: Animals; Cell Survival; Cells, Cultured; Chromosome Mapping; Cricetinae; Dose-Response Relationship, Drug; Drug Resistance; Ethyl Methanesulfonate; Genetic Variation; Hypoxanthine Phosphoribosyltransferase; In Vitro Techniques; Mesylates; Mutation; Probability; Thioguanine | 1975 |
Further evidence for the genetic origin of mutations in mammalian somatic cells: the effects of ploidy level and selection stringency on dose-dependent chemical mutagenesis to purine analogue resistance in Chinese hamster ovary cells.
Topics: Azaguanine; Cell Line; Dose-Response Relationship, Drug; Drug Resistance; Ethyl Methanesulfonate; Mesylates; Mutagens; Mutation; Ploidies; Selection, Genetic; Thioguanine | 1977 |
Methyl methanesulphonate mutagenesis in L5178Y mouse lymphoma cells.
Topics: Cell Line; Dose-Response Relationship, Drug; Drug Resistance; Ethyl Methanesulfonate; Lymphoma; Mesylates; Methyl Methanesulfonate; Mutagens; Mutation; Neoplasms, Experimental; Ouabain; Thioguanine; Thymidine | 1978 |
Chemical mutagenesis of mammalian cells can be quantified.
Topics: Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Hypoxanthine Phosphoribosyltransferase; Mutagens; Thioguanine; Time Factors | 1977 |
Isolation of drug-resistant clones of Ehrlich ascites tumor cells.
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Clone Cells; Drug Resistance; Ethyl Methanesulfonate; Guanosine; Mutagens; Neoplasm Transplantation; Thioguanine | 1976 |
Genetic complementation in hybrid cells derived from mutagen-induced mouse clones deficient in HGPRT activity.
Topics: Adenocarcinoma; Animals; Autoradiography; Azaguanine; Cell Line; Cell Survival; Chromosomes; Clone Cells; Ethyl Methanesulfonate; Genes; Genetic Complementation Test; Hybrid Cells; Hypoxanthine Phosphoribosyltransferase; Methylnitronitrosoguanidine; Mice; Mice, Inbred C3H; Mutation; Polyploidy; Temperature; Thioguanine | 1975 |
A mutational assay system for L5178Y mouse lymphoma cells, using hypoxanthine-guanine-phosphoribosyl-transferase (HGPRT) -deficiency as marker. The occurrence of a long expression time for mutations induced by X-rays and EMS.
Topics: Animals; Cell Line; Drug Resistance; Ethyl Methanesulfonate; Gene Frequency; Hypoxanthine Phosphoribosyltransferase; Lymphoma; Mice; Mutagens; Mutation; Radiation Genetics; Thioguanine; X-Rays | 1975 |
Ethyl methanesulphonate mutagenesis with L5178Y mouse lymphoma cells: a comparison of ouabain, thioguanine and excess thymidine resistance.
Topics: Animals; Cell Survival; Clone Cells; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance; Ethyl Methanesulfonate; Genetic Variation; Methotrexate; Mice; Mice, Inbred DBA; Mutation; Ouabain; Thioguanine; Thymidine | 1976 |
Application of the standard mutagenesis assay results in underestimation of ethyl methanesulphonate-induced mutations to ouabain-resistance in Chinese hamster cells.
Topics: Animals; Azaguanine; Cells, Cultured; Cricetinae; Drug Resistance; Ethyl Methanesulfonate; Mutagenicity Tests; Mutation; Ouabain; Thioguanine | 1992 |
Different modifications by vanillin in cytotoxicity and genetic changes induced by EMS and H2O2 in cultured Chinese hamster cells.
Topics: Animals; Benzaldehydes; Cells, Cultured; Chi-Square Distribution; Chromosome Aberrations; Cricetinae; Cricetulus; DNA Repair; Ethyl Methanesulfonate; Flavoring Agents; Hydrogen Peroxide; Male; Mutagenesis; Mutagenicity Tests; Mutation; Thioguanine | 1992 |
Genotoxicity of 2,4,6-trichlorophenol in V79 Chinese hamster cells.
Topics: Animals; Carcinogens; Cell Line; Cell Survival; Chlorophenols; Chromosome Aberrations; Cricetinae; Cricetulus; Diploidy; Dose-Response Relationship, Drug; Drug Resistance; Ethyl Methanesulfonate; Hypoxanthine Phosphoribosyltransferase; Micronucleus Tests; Mutagenicity Tests; Mutagens; Thioguanine | 1992 |
Induction of resistance to 6-thioguanine and cytarabine by a range of anticancer drugs in Chinese hamster AA8 cells.
Topics: Amsacrine; Animals; Antineoplastic Agents; Bleomycin; Carmustine; CHO Cells; Clone Cells; Cricetinae; Cytarabine; Daunorubicin; DNA Damage; Drug Resistance; Ethyl Methanesulfonate; Micronuclei, Chromosome-Defective; Stem Cells; Thioguanine; Time Factors; Topoisomerase I Inhibitors; Tumor Stem Cell Assay | 1992 |
Genotoxicity of 1-nitronaphthalene in Chinese hamster V79 cells.
Topics: Animals; Benz(a)Anthracenes; Biotransformation; Cell Line; Cricetinae; Drug Resistance; Ethyl Methanesulfonate; Liver; Mutagenicity Tests; Mutagens; Naphthalenes; Rats; Sister Chromatid Exchange; Thioguanine | 1991 |
A statistical evaluation of the reproducibility of micronucleus, sister-chromatid exchange, thioguanine-resistance and ouabain-resistance assays in V79 cells exposed to ethyl methanesulfonate and 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Cell Line; Cells, Cultured; Drug Resistance; Ethyl Methanesulfonate; Liver; Male; Micronucleus Tests; Mutagenicity Tests; Mutagens; Ouabain; Rats; Rats, Inbred F344; Sister Chromatid Exchange; Statistics as Topic; Thioguanine | 1990 |
Inherent sensitivity and induced resistance to chemotherapeutic drugs and irradiation in human cancer cell lines: relationship to mutation frequencies.
Topics: Antineoplastic Agents; Cisplatin; DNA; Dose-Response Relationship, Drug; Drug Resistance; Ethyl Methanesulfonate; Humans; Hypoxanthine Phosphoribosyltransferase; In Vitro Techniques; Male; Mutation; Testicular Neoplasms; Thioguanine; Urinary Bladder Neoplasms | 1990 |
Activation of a nonexpressed hypoxanthine phosphoribosyltransferase allele in mutant H23 HeLa cells by agents that inhibit DNA methylation.
Topics: Alleles; Azacitidine; Azaserine; Ethyl Methanesulfonate; Genes; HeLa Cells; Humans; Hypoxanthine Phosphoribosyltransferase; Methylation; Methylnitronitrosoguanidine; Mutation; Thioguanine | 1986 |
Induction of hypoxanthine phosphoribosyltransferase deficiency in human U-937 cells.
Topics: Autoradiography; Cell Division; Drug Resistance; Ethyl Methanesulfonate; Humans; Hybrid Cells; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Macrophages; Monocytes; Mutation; Phenotype; Scintillation Counting; Thioguanine | 1986 |
Enhancing effects of cytosine arabinoside on ethyl methanesulfonate-induced 6-thioguanine resistance mutations in Chinese hamster V79 cells.
Topics: Animals; Cell Line; Cell Survival; Cricetinae; Cytarabine; Drug Resistance; Drug Synergism; Ethyl Methanesulfonate; Mutation; Thioguanine | 1987 |
[Macrophage-mediated induction of drug-resistance variants in a mouse mammary tumor cell line].
Topics: Animals; Cell Line; Cells, Cultured; Drug Resistance; Ethyl Methanesulfonate; Female; Macrophage Activation; Macrophages; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mutation; Thioguanine | 1986 |
Increased persistence of induced mutants of Chinese hamster cells by 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Cells, Cultured; Cricetinae; Cricetulus; Culture Media; Ethyl Methanesulfonate; Female; Mutation; Ovary; Phorbols; Probability; Tetradecanoylphorbol Acetate; Thioguanine | 1986 |
Correlation of frequency of induced mutation and metastatic potential in tumor cell lines from a single mouse mammary tumor.
Topics: Animals; Cell Count; Cell Line; Drug Resistance; Ethyl Methanesulfonate; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mutation; Neoplasm Metastasis; Ouabain; Thioguanine | 1985 |
Studies on temperature-sensitive mutants of Chinese hamster ovary cells affected in DNA synthesis.
Topics: Alkylating Agents; Animals; Cell Division; Cell Line; Cell Survival; Cricetinae; Cricetulus; DNA; DNA Replication; Drug Resistance; Ethyl Methanesulfonate; Female; Genetic Complementation Test; Genetic Linkage; Hybrid Cells; Methyl Methanesulfonate; Mutation; Ouabain; Ovary; Protein Biosynthesis; RNA; Temperature; Thioguanine | 1980 |
Mutagen treatment as a means for selecting immunogenic variants from otherwise poorly immunogenic malignant murine tumors.
Topics: Adenocarcinoma; Animals; Ethyl Methanesulfonate; Mammary Neoplasms, Experimental; Mast-Cell Sarcoma; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Mutagens; Ouabain; Thioguanine | 1983 |
Induction of 6-thioguanine-resistant mutants and SCEs by 3 chemical mutagens (EMS, ENU and MMC) in cultured human blood lymphocytes.
Topics: Cell Cycle; Cells, Cultured; Drug Resistance; Ethyl Methanesulfonate; Ethylnitrosourea; Humans; Hypoxanthine Phosphoribosyltransferase; Lymphocytes; Mitomycin; Mitomycins; Mutation; Nitrosourea Compounds; Sister Chromatid Exchange; Thioguanine | 1984 |
Mutagenicity testing in mammalian cells. II. Validation of multiple drug-resistance markers having practical application for screening potential mutagens.
Topics: 4-Nitroquinoline-1-oxide; Adenine; Adenine Phosphoribosyltransferase; Animals; Benzopyrenes; Biotransformation; Cricetinae; Cricetulus; Dimethylnitrosamine; Drug Resistance; Ethyl Methanesulfonate; Floxuridine; Genetic Markers; Methylnitronitrosoguanidine; Microsomes, Liver; Mutagenicity Tests; Ouabain; Pentosyltransferases; Rats; Thioguanine; Thymidine Kinase | 1980 |
Isolation of Chinese hamster cells hyposensitive to ethyl methanesulfonate and their characterization in induction and antagonization of sister-chromatid exchanges.
Topics: Animals; Bromodeoxyuridine; Cell Line; Cricetinae; Cricetulus; Cycloheximide; Drug Resistance; Ethyl Methanesulfonate; Female; Mutation; Ovary; Recombination, Genetic; Sister Chromatid Exchange; Thioguanine | 1984 |
The nature of mutants induced by ionising radiation in cultured hamster cells. I. Isolation and initial characterisation of spontaneous, ionising radiation-induced, and ethyl methanesulphonate-induced mutants resistant to 6-thioguanine.
Topics: Animals; Cricetinae; Cricetulus; Drug Resistance; Ethyl Methanesulfonate; Gamma Rays; Glucosephosphate Dehydrogenase; Hypoxanthine Phosphoribosyltransferase; Karyotyping; Male; Mutation; Radiation, Ionizing; Thioguanine | 1984 |
Cross-resistance studies with V79 Chinese hamster cells adapted to the mutagenic or clastogenic effect of N-methyl-N'-nitro-N-nitrosoguanidine.
Topics: Animals; Cell Line; Cell Survival; Cricetinae; Cricetulus; Drug Resistance; Ethyl Methanesulfonate; Ethylnitrosourea; Lung; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Methylnitrosourea; Mutagens; Thioguanine; Ultraviolet Rays | 1983 |
8-Azaguanine versus 6-thioguanine: influence on frequency and expression time of induced HGPRT- mutations in Chinese hamster V79 cells.
Topics: Animals; Azaguanine; Cell Survival; Clone Cells; Cricetinae; Cricetulus; Drug Resistance; Ethyl Methanesulfonate; Hypoxanthine Phosphoribosyltransferase; Mutation; Phenotype; Thioguanine; Time Factors | 1983 |
Antagonization by cycloheximide of ethyl methanesulfonate-induced 6-thioguanine-resistant mutation and sister-chromatid exchanges.
Topics: Animals; Cells, Cultured; Cricetinae; Cricetulus; Crossing Over, Genetic; Cycloheximide; Drug Resistance; Ethyl Methanesulfonate; Female; Mutagens; Mutation; Ovary; Protein Biosynthesis; Sister Chromatid Exchange; Thioguanine | 1982 |
Phenotypic expression time of mutagen-induced 6-thioguanine resistance in Chinese hamster ovary cells (CHO/HGPRT system): expression in division-arrested cell cultures.
Topics: Animals; Cell Division; Cells, Cultured; Cricetinae; Cricetulus; Culture Media; Drug Resistance; Ethyl Methanesulfonate; Female; Hypoxanthine Phosphoribosyltransferase; Mutation; Ovary; Phenotype; Proteins; Thioguanine | 1982 |
Relative sensitivity of V79 and V79/79 cells to spontaneous and induced mutation to 6-thioguanine and ouabain resistance.
Topics: Animals; Cell Line; Cricetinae; Cricetulus; Drug Resistance; Ethyl Methanesulfonate; Lung; Methylnitrosourea; Mutagens; Mutation; Ouabain; Phenotype; Species Specificity; Thioguanine; Ultraviolet Rays | 1982 |
Ploidy dependence of induced mutation frequency in transformed Syrian hamster cells.
Topics: Aneuploidy; Animals; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Drug Resistance; Embryo, Mammalian; Ethyl Methanesulfonate; Gene Frequency; Genes, Dominant; Genes, Recessive; Hypoxanthine Phosphoribosyltransferase; Mesocricetus; Mutagens; Ouabain; Phenotype; Thioguanine; Time Factors | 1980 |
Isolation of somatic cell mutants with specified alterations in hypoxanthine phosphoribosyltransferase.
Topics: Animals; Azaguanine; Cell Line; Drug Resistance; Ethyl Methanesulfonate; Genes; Hypoxanthine Phosphoribosyltransferase; Methylnitronitrosoguanidine; Mice; Thioguanine | 1980 |
Pluripotency of somatic cell hybrids between nullipotent and pluripotent embryonal carcinoma cells.
Topics: Animals; Cell Differentiation; Drug Resistance; Ethyl Methanesulfonate; Genes, Dominant; Hybrid Cells; Male; Mice; Neoplasms, Experimental; Ouabain; Phenotype; Teratoma; Thioguanine | 1980 |
Marked differences in the role of O6-alkylguanine in hprt mutagenesis in T-lymphocytes of rats exposed in vivo to ethylmethanesulfonate, N-(2-hydroxyethyl)-N-nitrosourea, or N-ethyl-N-nitrosourea.
Topics: Adenine; Animals; Base Composition; Base Sequence; Carcinogens; DNA Adducts; DNA, Complementary; Drug Resistance; Ethyl Methanesulfonate; Ethylnitrosourea; Guanine; Hypoxanthine Phosphoribosyltransferase; In Vitro Techniques; Male; Molecular Sequence Data; Mutagenesis; Point Mutation; Polymerase Chain Reaction; Rats; Rats, Inbred Lew; T-Lymphocytes; Thioguanine; Thymidine | 1995 |
Spectrum of mutations induced by methyl and ethyl methanesulfonate at the hprt locus of normal and tag expressing Chinese hamster fibroblasts.
Topics: Alkylation; Animals; Base Sequence; Cell Line; Cricetinae; Cricetulus; DNA Glycosylases; DNA Primers; DNA Repair; Ethyl Methanesulfonate; Hypoxanthine Phosphoribosyltransferase; Methyl Methanesulfonate; Molecular Sequence Data; Mutagenesis; N-Glycosyl Hydrolases; Thioguanine; Transfection | 1995 |
Folate deficiency increases genetic damage caused by alkylating agents and gamma-irradiation in Chinese hamster ovary cells.
Topics: Animals; Cell Survival; CHO Cells; Cricetinae; Diphtheria Toxin; DNA; DNA Damage; Ethyl Methanesulfonate; Folic Acid Deficiency; Hypoxanthine Phosphoribosyltransferase; Methylnitrosourea; Point Mutation; Thioguanine | 1993 |
Effect of folate deficiency on mutations at the hprt locus in Chinese hamster ovary cells exposed to monofunctional alkylating agents.
Topics: Alkylating Agents; Animals; CHO Cells; Cricetinae; Ethyl Methanesulfonate; Ethylnitrosourea; Folic Acid Deficiency; Hypoxanthine Phosphoribosyltransferase; Mutation; Polymerase Chain Reaction; Thioguanine | 1997 |
Calibration of the single cell gel electrophoresis assay, flow cytometry analysis and forward mutation in Chinese hamster ovary cells.
Topics: Animals; Calibration; Cell Survival; CHO Cells; Clone Cells; Cricetinae; DNA Damage; Electrophoresis, Agar Gel; Ethyl Methanesulfonate; Flow Cytometry; Mutagenicity Tests; Point Mutation; Thioguanine | 1998 |
The effect of folate deficiency on the hprt mutational spectrum in Chinese hamster ovary cells treated with monofunctional alkylating agents.
Topics: Alkylating Agents; Animals; Base Pairing; CHO Cells; Cricetinae; DNA Mutational Analysis; DNA Primers; DNA Repair; Ethyl Methanesulfonate; Ethylnitrosourea; Folic Acid Deficiency; Guanine; Hypoxanthine Phosphoribosyltransferase; Mutagens; Mutation; Polymerase Chain Reaction; Thioguanine | 1999 |
Desmutagenic and bio-antimutagenic activity of docosahexaenoic acid and eicosapentaenoic acid in cultured Chinese hamster V79 cells.
Topics: Animals; Antimutagenic Agents; Cell Line; Cell Survival; Colony-Forming Units Assay; Cricetinae; Docosahexaenoic Acids; Eicosapentaenoic Acid; Ethyl Methanesulfonate; Mutagenicity Tests; Thioguanine | 2001 |
Characteristics of revertants induced by EMS and u.v. light from a 6-thioguanine resistant HGPRT deficient V79 Chinese hamster cell line.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Survival; CHO Cells; Cricetinae; Cricetulus; Drug Resistance; Ethyl Methanesulfonate; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Mutagenesis; Mutagens; Mutation; Phenotype; Thioguanine; Ultraviolet Rays | 1980 |