Compounds > ethyl methanesulfonate
Page last updated: 2024-08-17

ethyl methanesulfonate and mitomycin

ethyl methanesulfonate has been researched along with mitomycin in 71 studies

Research

Studies (71)

TimeframeStudies, this research(%)All Research%
pre-199031 (43.66)18.7374
1990's23 (32.39)18.2507
2000's13 (18.31)29.6817
2010's4 (5.63)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anderson, RF; Denny, WA; Thompson, LH; Wilson, WR1
Deleener, A; Kirsch-Volders, M; Van Hummelen, P; Vanparys, P1
Cortés, F; Daza, P; Escalza, P; Mateos, S1
Cortés, F; Daza, P; Escalza, P; Piñero, J2
Harris, AL; Hickson, ID; Robson, CN1
Pattee, PA; Tam, JE1
Denko, N; Giaccia, A; Patil, P; Peters, B; Stamato, TD; Weinstein, R1
Ikushima, T1
Buchwald, M; Clarke, C; Duckworth-Rysiecki, G; Ng, J; Toji, L1
Das, RK1
Andriadze, MI; Mikhel'son, VM; Pleskach, NM; Zhestianikov, VD1
Koizumi, A; Miura, K; Morimoto, K1
Capuano, V; Guerra, BR; Mondello, C; Nuzzo, F; Stefanini, M; Tessera, L1
Iijima, K; Morimoto, K1
Christensen, EA; Ellingham, TJ; Maddock, MB1
Nuzzo, F; Orecchia, G; Rabbiosi, G; Stefanini, M1
Oikawa, A; Tohda, H1
Kaufman, ER1
Hickson, ID; Robson, CN1
Cox, R; Jones, NJ; Thacker, J1
Hashimoto, T; Komatsu, S; Ohno, S; Ohno, Y; Takeuchi, K1
Hunt, G; Lakshmi, MS; Sherbet, GV1
Bowring, SN; Morris, JG1
Dambly-Chaudière, C; Radman, M; Tenenbaum, L; Toman, Z1
Evans, HJ; Newton, MS1
Evans, HJ; Newton, MS; Pentland, B1
Evans, HJ; Newton, MS; Pentland, B; Steel, CM1
Balganesh, M; Setlow, JK1
Evans, HJ1
Ros, Y1
Colyer, SP; DuFrain, RJ; Littlefield, LG; Sayer, AM1
Morimoto, K1
Ohno, K; Takeshita, K1
Anderson, D; Richardson, CR1
Jones, S; Kefford, RF; Mann, GJ; McDonald, DA; McKay, MJ1
Hayashi, M; Sofuni, T; Suzuki, T1
Hayashi, M; Honma, M; Matsuoka, A; Sofuni, T; Suzuki, T; Zhang, LS1
Anderson, D; Davies, MJ; Phillips, BJ; Rumbsy, PC1
Davies, MJ; Phillips, BJ; Rumsby, PC1
de Vogel, N; Rompelberg, CJ; Schouten, A; Stenhuis, WH; van Osenbruggen, WA; Verhagen, H1
Antoccia, A; Creus, A; Degrassi, F; Marcos, R; Peris, F; Surrallés, J; Tanzarella, C; Xamena, N1
Bronzetti, G; Fiorio, R; Vellosi, R1
Dragonetti, E; Giordano, V; Mallardo, M; Quinto, I; Scala, G1
Baldassarre, F; Dragonetti, E; Mallardo, M; Quinto, I; Ruocco, MR; Scala, G1
Koppen, G; Verschaeve, L1
Grompe, M; Jakobs, PM; Joenje, H; Moses, RE; Olson, S; Reifsteck, C; Sahaayaruban, P; Saito, H1
Hayashi, M; Honma, M; Sofuni, T1
Albert, RB; Brookman, KW; Busch, DB; Collins, A; de Wit, J; Hoeijmakers, J; Mitchell, DL; Riboni, R; Stefanini, M; Thompson, LH; van Gool, AJ; van Vuuren, H; Zdzienicka, MZ1
Buschini, A; Candi, A; Poli, P; Rossi, C1
Gustafson, DL; Snead, D; Trotter, BK; Waldren, CA1
Bärtsch, S; Sengstag, C; Würgler, FE1
Bourner, C; Fedyk, J; Henderson, L; Windebank, S; Wolfreys, A1
Böttger, EC; Frischkorn, K; Prammananan, T; Sander, P; Scholz, M; Teschner, K1
Mitchell, SA; Subkhankulova, T; Willis, AE1
Busch, DB; Coleman, D; Jones, NJ; McDonough, HG; White Ziffer, D; Wills, L1
Hashem, VI; Sinden, RR1
Anderson, D; Bibby, MC; Fearnley, J; Loadman, PM; Phillips, RM; Suggitt, M; Swaine, DJ; Volpato, M1
Berti, F; Cantelli-Forti, G; Fimognari, C; Hrelia, P2
Allkvist, A; Bergman, A; Erixon, K; Helleday, T; Jenssen, D; Johansson, F; Malmvärn, A; Nilsson, R1
Shuai, PQ; Wang, YJ; Zhang, LS1
Ashizawa, T; Hashem, VI; Khajav, M; Khajavi, M; Klysik, EA; Pytlos, MJ; Sinden, RR; Tsuji, K1
Fox, MH; French, CT; Joshi, DD; Keysar, SB; Lim, CU; Ross, CD1
Amaral, VS; de Andrade, HH; Dihl, RR; Furlanetto, MP; Sinigaglia, M1
Gu, MB; Kim, BC; Niazi, JH1
Cannella, M; Frati, L; Li, GM; Maglione, V; Martino, T; Ragona, G; Squitieri, F1
Kuehner, S; Linsenmeyer, R; Schütz, P; Speit, G1
Honma, M; Kimura, A; Miyata, A1
Kasahara, T; Matsuda, S; Wanibuchi, S1
Itoh, K; Masumori, S; Mukai, D; Sakakibara, H; Shimoi, K; Yasuda, M1

Other Studies

71 other study(ies) available for ethyl methanesulfonate and mitomycin

ArticleYear
Hypoxia-selective antitumor agents. 2. Electronic effects of 4-substituents on the mechanisms of cytotoxicity and metabolic stability of nitracrine derivatives.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:1

    Topics: Aminoacridines; Animals; Cell Division; Cell Line; DNA; Nitracrine; Oxygen; Structure-Activity Relationship

1989
Discrimination of aneuploidogens from clastogens by C-banding, DNA and area measurements of micronuclei from mouse bone marrow.
    Mutation research, 1992, Volume: 271, Issue:1

    Topics: Aneuploidy; Animals; Azacitidine; Azathioprine; Bone Marrow; Chromosome Banding; Colchicine; Dioxolanes; DNA; Ethyl Methanesulfonate; Female; Hydroquinones; Male; Mice; Micronucleus Tests; Mitomycin; Mutagens; Procarbazine; Vinblastine

1992
Mitomycin C, 4-nitroquinoline-1-oxide and ethyl methanesulfonate induce long-lived lesions in DNA which result in SCEs during successive cell cycles in human lymphocytes.
    Mutation research, 1992, Nov-16, Volume: 270, Issue:2

    Topics: 4-Nitroquinoline-1-oxide; Cell Cycle; DNA; DNA Damage; Ethyl Methanesulfonate; Humans; Lymphocytes; Mitomycin; Mutagenesis; Mutagens; Sister Chromatid Exchange; Time Factors

1992
Different effectiveness of 4-nitroquinoline-1-oxide, mitomycin C and ethyl methanesulfonate to induce lesions in DNA leading to sister chromatid exchange throughout successive cell cycles in Chinese hamster ovary cells.
    Mutagenesis, 1992, Volume: 7, Issue:2

    Topics: 4-Nitroquinoline-1-oxide; Animals; Cell Cycle; CHO Cells; Cricetinae; DNA; DNA Damage; DNA Repair; Ethyl Methanesulfonate; Mitomycin; Sister Chromatid Exchange

1992
Isolation and characterization of Chinese hamster ovary cell lines sensitive to mitomycin C and bleomycin.
    Cancer research, 1985, Volume: 45, Issue:11 Pt 1

    Topics: Animals; Bleomycin; Carmustine; Cell Line; Cell Survival; Cisplatin; Cricetinae; Cricetulus; DNA Repair; Doxorubicin; Ethyl Methanesulfonate; Female; Mitomycin; Mitomycins; Mutation; Ovary; Ultraviolet Rays; X-Rays

1985
Characterization and genetic mapping of a mutation affecting apurinic endonuclease activity in Staphylococcus aureus.
    Journal of bacteriology, 1986, Volume: 168, Issue:2

    Topics: 4-Nitroquinoline-1-oxide; Chromosome Mapping; Chromosomes, Bacterial; Deoxyribonuclease IV (Phage T4-Induced); DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; Endodeoxyribonucleases; Ethyl Methanesulfonate; Genes, Bacterial; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Mutation; Nitrous Acid; Recombination, Genetic; Staphylococcus aureus; Ultraviolet Rays

1986
Isolation and characterization of bleomycin-sensitive Chinese hamster ovary cells.
    Cancer research, 1987, Mar-15, Volume: 47, Issue:6

    Topics: Aminacrine; Animals; Bleomycin; Cell Line; Cell Separation; Cell Survival; Cricetinae; Cricetulus; DNA Damage; Ethyl Methanesulfonate; Female; Mitomycin; Mitomycins; Mutation; Nitrogen Mustard Compounds

1987
Radio-adaptive response: characterization of a cytogenetic repair induced by low-level ionizing radiation in cultured Chinese hamster cells.
    Mutation research, 1989, Volume: 227, Issue:4

    Topics: Animals; Beta Particles; Cell Line; Cisplatin; Cricetinae; Cricetulus; DNA Repair; Dose-Response Relationship, Radiation; Ethyl Methanesulfonate; Gamma Rays; In Vitro Techniques; Micronucleus Tests; Mitomycin; Mitomycins; Sister Chromatid Exchange; Time Factors; Tritium; Ultraviolet Rays

1989
Characterization of a simian virus 40-transformed Fanconi anemia fibroblast cell line.
    Mutation research, 1986, Volume: 166, Issue:2

    Topics: Anemia, Aplastic; Cell Cycle; Cell Line; Cell Survival; Cell Transformation, Viral; Chromosomes; Cross-Linking Reagents; DNA Repair; Ethyl Methanesulfonate; Fanconi Anemia; Humans; Karyotyping; Mitomycin; Mitomycins; Simian virus 40; Transfection

1986
Mitomycin C and ethyl methanesulphonate-induced sister-chromatid exchanges in lymphocytes from individuals with Alzheimer's pre-senile dementia.
    Mutation research, 1986, Volume: 173, Issue:2

    Topics: Age Factors; Aged; Alzheimer Disease; Cells, Cultured; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Female; Humans; Lymphocytes; Male; Middle Aged; Mitomycin; Mitomycins; Mutagenicity Tests; Sister Chromatid Exchange

1986
[Spontaneous and induced sister chromatid exchanges in the blood lymphocytes of healthy persons and of xeroderma pigmentosum patients exposed to the inhibitors of DNA repair and replication caffeine, 3-methoxybenzamide and novobiocin].
    Tsitologiia, 1986, Volume: 28, Issue:1

    Topics: Adult; Benzamides; Caffeine; Cells, Cultured; DNA Repair; DNA Replication; Ethyl Methanesulfonate; Humans; Lymphocyte Activation; Lymphocytes; Middle Aged; Mitomycin; Mitomycins; Novobiocin; Phytohemagglutinins; Sister Chromatid Exchange; Ultraviolet Rays; Xeroderma Pigmentosum

1986
Effects of temperature on chemically induced sister-chromatid exchange in human lymphocytes.
    Mutation research, 1986, Volume: 174, Issue:1

    Topics: 4-Nitroquinoline-1-oxide; Cell Cycle; Ethyl Methanesulfonate; Humans; In Vitro Techniques; Mitomycin; Mitomycins; Mutagenicity Tests; Sister Chromatid Exchange; Temperature

1986
Sensitivity to DNA-damaging agents and mutation induction by UV light in UV-sensitive CHO cells.
    Mutation research, 1986, Volume: 174, Issue:2

    Topics: Animals; Cell Line; Cell Survival; Cricetinae; Cricetulus; Ethyl Methanesulfonate; Female; Hydrogen Peroxide; Lomustine; Mitomycin; Mitomycins; Mutation; Ovary; Ultraviolet Rays; X-Rays

1986
Cell-stage dependence of mutagen-induced sister-chromatid exchanges in human lymphocyte cultures.
    Mutation research, 1986, Volume: 162, Issue:1

    Topics: 4-Nitroquinoline-1-oxide; Adult; Cell Cycle; Cells, Cultured; Ethyl Methanesulfonate; Female; Humans; Lymphocytes; Mitomycin; Mitomycins; Mutagens; Sister Chromatid Exchange

1986
In vitro induction of sister chromatid exchanges and chromosomal aberrations in peripheral lymphocytes of the oyster toadfish and American eel.
    Environmental mutagenesis, 1986, Volume: 8, Issue:4

    Topics: Animals; Bromodeoxyuridine; Cell Division; Chromosome Aberrations; Dose-Response Relationship, Drug; Eels; Ethyl Methanesulfonate; Fishes; In Vitro Techniques; Lymphocytes; Metaphase; Mitomycin; Mitomycins; Sister Chromatid Exchange; Water Pollutants; Water Pollutants, Chemical

1986
Altered cellular response to UV irradiation in a patient affected by premature ageing.
    Human genetics, 1986, Volume: 73, Issue:3

    Topics: Adult; DNA Repair; DNA Replication; Ethyl Methanesulfonate; Fibroblasts; Humans; In Vitro Techniques; Lymphocytes; Male; Middle Aged; Mitomycin; Mitomycins; Progeria; Ultraviolet Rays

1986
Proliferation-dependent reduction of sister-chromatid exchange frequency induced by mitomycin C in human lymphoblastoid cells and its suppression by inhibitors of DNA replication.
    Mutation research, 1986, Volume: 163, Issue:2

    Topics: 4-Nitroquinoline-1-oxide; Cell Division; Cycloheximide; Cytarabine; Depression, Chemical; DNA Repair; DNA Replication; Ethyl Methanesulfonate; Humans; Hydroxyurea; Lymphocytes; Mitomycin; Mitomycins; Sister Chromatid Exchange

1986
Uncoupling of the induction of mutations and sister-chromatid exchanges by the replication of 5-bromouracil-substituted DNA.
    Mutation research, 1987, Volume: 176, Issue:1

    Topics: Animals; Bromodeoxyuridine; Cell Line; Cricetinae; DNA; DNA Repair; Ethyl Methanesulfonate; Mitomycin; Mitomycins; Mutation; Sister Chromatid Exchange

1987
Isolation of alkylating agent-sensitive Chinese hamster ovary cell lines.
    Carcinogenesis, 1987, Volume: 8, Issue:4

    Topics: Alkylating Agents; Animals; Cell Line; Cell Survival; Cricetinae; Cricetulus; DNA Damage; DNA Repair; Ethyl Methanesulfonate; Ethylnitrosourea; Melphalan; Methylnitrosourea; Mitomycin; Mitomycins; Mutation

1987
Isolation and cross-sensitivity of X-ray-sensitive mutants of V79-4 hamster cells.
    Mutation research, 1987, Volume: 183, Issue:3

    Topics: Animals; Cell Line; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; DNA Repair; Ethyl Methanesulfonate; Ethylnitrosourea; Karyotyping; Mitomycin; Mitomycins; Mutation; Ultraviolet Rays; X-Rays

1987
Cytogenic analysis of dominant lethal effects of mitomycin C and ethyl methanesulfonate.
    The Journal of toxicological sciences, 1987, Volume: 12, Issue:1

    Topics: Animals; Bone Marrow; Chromosome Aberrations; Ethyl Methanesulfonate; Female; Germ Cells; Male; Mice; Mice, Inbred ICR; Mitomycin; Mitomycins; Mutagens; Spermatocytes; Spermatogonia; Zygote

1987
Spontaneous sister chromatid exchange in metastatic variants of the murine B16 melanoma and human astrocytomas in culture.
    Invasion & metastasis, 1988, Volume: 8, Issue:4

    Topics: Animals; Astrocytoma; Ethyl Methanesulfonate; Humans; Melanoma, Experimental; Mice; Mitomycin; Mitomycins; Neoplasm Metastasis; Ploidies; Sister Chromatid Exchange; Tumor Cells, Cultured

1988
Mutagenesis of Clostridium acetobutylicum.
    The Journal of applied bacteriology, 1985, Volume: 58, Issue:6

    Topics: Clostridium; DNA Repair; Ethyl Methanesulfonate; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Mutation

1985
A system for detection of genetic and epigenetic alterations in Escherichia coli induced by DNA-damaging agents.
    Journal of molecular biology, 1985, Nov-05, Volume: 186, Issue:1

    Topics: Aflatoxin B1; Aflatoxins; Antibiotics, Antineoplastic; Carcinogens; DNA Repair; Escherichia coli; Ethyl Methanesulfonate; Galactokinase; Gamma Rays; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Mutagenicity Tests; Mutagens; Recombination, Genetic; Ultraviolet Rays

1985
The response of cells from patients with Huntington's chorea to mutagen-induced chromosome damage.
    Annals of human genetics, 1982, Volume: 46, Issue:2

    Topics: Cells, Cultured; Chromosome Aberrations; Chromosomes, Human; Crossing Over, Genetic; DNA; Ethyl Methanesulfonate; Female; Humans; Huntington Disease; Lymphocytes; Male; Mitomycin; Mitomycins; Mutagens; Sister Chromatid Exchange; Skin

1982
Mutagen hypersensitivity in Friedreich's ataxia.
    Annals of human genetics, 1983, Volume: 47, Issue:3

    Topics: Adult; Chromosome Aberrations; Crossing Over, Genetic; Ethyl Methanesulfonate; Female; Friedreich Ataxia; Humans; Lymphocytes; Male; Mitomycin; Mitomycins; Sister Chromatid Exchange

1983
Spontaneous and mutagen induced sister chromatid exchange in multiple sclerosis.
    Journal of medical genetics, 1983, Volume: 20, Issue:5

    Topics: Adult; Crossing Over, Genetic; DNA Repair; Ethyl Methanesulfonate; Female; Humans; In Vitro Techniques; Lymphocytes; Male; Middle Aged; Mitomycin; Mitomycins; Multiple Sclerosis; Mutagens; Sister Chromatid Exchange

1983
Prophage induction in Haemophilus influenzae and its relationship to mutation by chemical and physical agents.
    Mutation research, 1984, Volume: 125, Issue:1

    Topics: Bacteriophages; Ethyl Methanesulfonate; Haemophilus influenzae; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Mutagens; Mutation; Ultraviolet Rays; Virus Activation

1984
Induction of 6-thioguanine-resistant mutants and SCEs by 3 chemical mutagens (EMS, ENU and MMC) in cultured human blood lymphocytes.
    Mutation research, 1984, Volume: 129, Issue:2

    Topics: Cell Cycle; Cells, Cultured; Drug Resistance; Ethyl Methanesulfonate; Ethylnitrosourea; Humans; Hypoxanthine Phosphoribosyltransferase; Lymphocytes; Mitomycin; Mitomycins; Mutation; Nitrosourea Compounds; Sister Chromatid Exchange; Thioguanine

1984
[Use of in-vitro treated human blood cells for the detection of the potential genotoxicity of chemical agents].
    Archives belges = Belgisch archief, 1984, Volume: 42, Issue:5-6

    Topics: Acrylamides; Benzopyrenes; Carcinogens; Chromosome Aberrations; Cyclophosphamide; Ethyl Methanesulfonate; Humans; Lymphocyte Activation; Mitomycin; Mitomycins; Mutagens; Tetradecanoylphorbol Acetate

1984
Persistence of SCE-inducing lesions after G0 exposure of human lymphocytes to differing classes of DNA-damaging chemicals.
    Basic life sciences, 1984, Volume: 29 Pt B

    Topics: Alkylating Agents; Cells, Cultured; Cisplatin; DNA Repair; Ethyl Methanesulfonate; Humans; Interphase; Lymphocytes; Mitomycin; Mitomycins; Sister Chromatid Exchange; Thiotepa

1984
Proliferative kinetics and chemical-induced sister chromatid exchanges in human lymphocyte cultures.
    Basic life sciences, 1984, Volume: 29 Pt B

    Topics: 4-Nitroquinoline-1-oxide; Cell Cycle; Cell Division; Cells, Cultured; DNA Repair; DNA Replication; Ethyl Methanesulfonate; Humans; Lymphocytes; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Nitrosourea Compounds; Sister Chromatid Exchange

1984
Patients with tuberous sclerosis have fibroblasts with normal limits for growth characteristics and sensitivities to DNA alkylating agents.
    Jinrui idengaku zasshi. The Japanese journal of human genetics, 1984, Volume: 29, Issue:3

    Topics: 4-Nitroquinoline-1-oxide; Adolescent; Adult; Cell Division; Cell Survival; Cells, Cultured; Child; DNA Repair; Ethyl Methanesulfonate; Fibroblasts; Humans; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Skin; Tuberous Sclerosis

1984
Issues relevant to the assessment of chemically induced chromosome damage in vivo and their relationship to chemical mutagenesis.
    Mutation research, 1981, Volume: 90, Issue:3

    Topics: Animals; Benzene; Bone Marrow; Chromosome Aberrations; Chromosomes; Ethyl Methanesulfonate; Male; Mitomycin; Mitomycins; Mutagens; Rats; Vinyl Chloride

1981
Isolation and preliminary characterisation of an X-ray-sensitive mammalian mutant cell line (WMXRS-1).
    Mutation research, 1994, Volume: 314, Issue:3

    Topics: Animals; Bleomycin; Cell Cycle; Cell Line; Cell Survival; Cisplatin; DNA; DNA Damage; DNA Repair; Ethyl Methanesulfonate; Fibroblasts; Hydrogen Peroxide; Mice; Micronucleus Tests; Mitomycin; Mutagenesis; Mutation; Radiation Tolerance; Ultraviolet Rays

1994
Initial experiences and future directions for transgenic mouse mutation assays.
    Mutation research, 1994, Jun-01, Volume: 307, Issue:2

    Topics: Animals; Bone Marrow; Bone Marrow Cells; Color; Diethylnitrosamine; DNA Transposable Elements; Ethyl Methanesulfonate; Ethylnitrosourea; Lac Operon; Liver; Male; Mice; Mice, Transgenic; Micronucleus Tests; Mitomycin; Models, Genetic; Mutagenesis, Site-Directed; Mutagenicity Tests; Mutagens; Mutation

1994
Evidence that SCEs induced by mutagens do not occur at the same locus in successive cell cycles: lack of cancellation in three-way stained CHO chromosomes.
    Environmental and molecular mutagenesis, 1994, Volume: 24, Issue:3

    Topics: Animals; Bromodeoxyuridine; Cell Cycle; CHO Cells; Chromosomes; Cricetinae; DNA Damage; DNA Repair; Ethyl Methanesulfonate; Metaphase; Mitomycin; Mutagenesis; Mutagenicity Tests; Sister Chromatid Exchange; Staining and Labeling; Ultraviolet Rays

1994
A comparative study of TK6 human lymphoblastoid and L5178Y mouse lymphoma cell lines in the in vitro micronucleus test.
    Mutation research, 1995, Volume: 347, Issue:3-4

    Topics: Animals; B-Lymphocytes; Cell Line; Cell Survival; Demecolcine; Ethyl Methanesulfonate; Humans; Leukemia L5178; Lymphoma; Methyl Methanesulfonate; Mice; Micronucleus Tests; Mitomycin; Mutagens; Tumor Cells, Cultured; Vincristine; X-Rays

1995
Molecular analysis of mutation at the hprt locus of Chinese hamster V79 cells induced by ethyl methanesulphonate and mitomycin C.
    Mutation research, 1993, Volume: 291, Issue:2

    Topics: Animals; Blotting, Northern; Blotting, Southern; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; DNA Mutational Analysis; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Gene Deletion; Hypoxanthine Phosphoribosyltransferase; Lung; Mitomycin; Mutagenesis, Site-Directed; Mutagenicity Tests; Point Mutation; RNA, Messenger

1993
Molecular analysis of mutations at the tk locus of L5178Y mouse-lymphoma cells induced by ethyl methanesulphonate and mitomycin C.
    Mutation research, 1993, Volume: 290, Issue:2

    Topics: Animals; Blotting, Northern; Blotting, Southern; DNA Mutational Analysis; Ethyl Methanesulfonate; Gene Deletion; Leukemia L5178; Mice; Mitomycin; Mutagenesis; Mutagenicity Tests; Mutagens; Point Mutation; Thymidine Kinase; Tumor Cells, Cultured

1993
Antimutagenicity of eugenol in the rodent bone marrow micronucleus test.
    Mutation research, 1995, Volume: 346, Issue:2

    Topics: Administration, Oral; Animals; Antimutagenic Agents; Bone Marrow; Bone Marrow Cells; Cyclophosphamide; Ethyl Methanesulfonate; Eugenol; Male; Mice; Micronucleus Tests; Mitomycin; Mutagenesis

1995
The effect of cytochalasin-B concentration on the frequency of micronuclei induced by four standard mutagens. Results from two laboratories.
    Mutagenesis, 1994, Volume: 9, Issue:4

    Topics: Adult; Artifacts; Cells, Cultured; Colchicine; Cytochalasin B; Dose-Response Relationship, Drug; Drug Synergism; Ethyl Methanesulfonate; Humans; Lymphocytes; Male; Micronucleus Tests; Mitomycin; Mutagens; Vincristine

1994
Effects of spermine on formation of HGPRT- mutants induced by ethylmethanesulfonate, methylmethanesulfonate, and mitomycin C in V79 Chinese hamster cells.
    Environmental and molecular mutagenesis, 1994, Volume: 23, Issue:4

    Topics: Alkylation; Animals; Antimutagenic Agents; Binding, Competitive; Cells, Cultured; Cricetinae; Cricetulus; Ethyl Methanesulfonate; Glutathione; Glutathione Transferase; Hypoxanthine Phosphoribosyltransferase; Lung; Methyl Methanesulfonate; Mitomycin; Mutagenesis; Mutagenicity Tests; Mutagens; Spermine

1994
DNA damaging agents increase the stability of interleukin-1 alpha, interleukin-1 beta, and interleukin-6 transcripts and the production of the relative proteins.
    The Journal of biological chemistry, 1994, May-27, Volume: 269, Issue:21

    Topics: Carcinogens; Cells, Cultured; DNA Damage; Ethyl Methanesulfonate; Gene Expression Regulation; Humans; Interleukin-1; Interleukin-6; Methyl Methanesulfonate; Mitomycin; Monocytes; RNA, Messenger; Transcription, Genetic

1994
The human immunodeficiency virus type 1 long terminal repeat is activated by monofunctional and bifunctional DNA alkylating agents in human lymphocytes.
    The Journal of biological chemistry, 1993, Dec-15, Volume: 268, Issue:35

    Topics: Alkylating Agents; Base Sequence; Cell Line; Chloramphenicol O-Acetyltransferase; Ethyl Methanesulfonate; HIV Long Terminal Repeat; HIV-1; Humans; Lymphocytes; Methyl Methanesulfonate; Mitomycin; Molecular Sequence Data; Mutagens; NF-kappa B; Nuclear Proteins; Sp1 Transcription Factor; Virus Activation

1993
The alkaline comet test on plant cells: a new genotoxicity test for DNA strand breaks in Vicia faba root cells.
    Mutation research, 1996, Aug-08, Volume: 360, Issue:3

    Topics: Cadmium; Cadmium Chloride; Chlorides; Chromium Compounds; Cycloheximide; DNA Damage; Electrophoresis, Agar Gel; Ethyl Methanesulfonate; Fabaceae; Genetic Techniques; Methyl Methanesulfonate; Mitomycin; Models, Statistical; Mutagenicity Tests; Plant Roots; Plants, Medicinal; Protein Synthesis Inhibitors; Software

1996
Immortalization of four new Fanconi anemia fibroblast cell lines by an improved procedure.
    Somatic cell and molecular genetics, 1996, Volume: 22, Issue:2

    Topics: Cell Culture Techniques; Cell Fusion; Cell Line, Transformed; Cell Survival; Chromosome Aberrations; Epoxy Compounds; Ethyl Methanesulfonate; Fanconi Anemia; Fibroblasts; Genetic Complementation Test; Humans; Karyotyping; Mitomycin; Mutagens; Phenotype; Skin

1996
Cytotoxic and mutagenic responses to X-rays and chemical mutagens in normal and p53-mutated human lymphoblastoid cells.
    Mutation research, 1997, Mar-04, Volume: 374, Issue:1

    Topics: Cell Line; Chromosome Breakage; Chromosome Deletion; DNA Fingerprinting; Ethyl Methanesulfonate; Genes, p53; Humans; Lymphocytes; Methyl Methanesulfonate; Mitomycin; Mutagens; X-Rays

1997
Phenotypic heterogeneity in nucleotide excision repair mutants of rodent complementation groups 1 and 4.
    Mutation research, 1997, Mar-12, Volume: 383, Issue:2

    Topics: Acetoxyacetylaminofluorene; Adenine; Alleles; Animals; Cells, Cultured; CHO Cells; Cricetinae; DNA; DNA Repair; DNA-Binding Proteins; DNA, Complementary; Endonucleases; Ethyl Methanesulfonate; Gamma Rays; Genetic Complementation Test; HeLa Cells; Humans; Immunosorbent Techniques; Mitomycin; Mutagens; Proteins; RNA; Transfection; Ultraviolet Rays

1997
Modulation of mitomycin C mutagenicity on Saccharomyces cerevisiae by glutathione, cytochrome P-450, and mitochondria interactions.
    Mutation research, 1997, Apr-24, Volume: 390, Issue:1-2

    Topics: Buthionine Sulfoximine; Cytochrome P-450 Enzyme System; Ethyl Methanesulfonate; Gene Conversion; Glutathione; Hycanthone; Mitochondria; Mitomycin; Mutagenesis; Mutagens; Nucleic Acid Synthesis Inhibitors; Point Mutation; Saccharomyces cerevisiae

1997
Expression of human O6-methyl guanine methyl transferase (MGMT) in post replication repair (PRR) deficient CHO-UV-1 cells: compensation for hypersensitivity to methylating and ethylating agents but not to mitomycin C.
    Somatic cell and molecular genetics, 1997, Volume: 23, Issue:1

    Topics: Alkylating Agents; Animals; CHO Cells; Cricetinae; DNA Methylation; DNA Repair; Ethyl Methanesulfonate; Humans; Methylnitronitrosoguanidine; Methyltransferases; Mitomycin; O(6)-Methylguanine-DNA Methyltransferase

1997
A genetic system to detect mitotic recombination between repeated chromosomal sequences in Drosophila Schneider line 2 cells.
    Mutation research, 1997, Dec-05, Volume: 395, Issue:1

    Topics: Animals; beta-Galactosidase; Cells, Cultured; Chromosomes; Drosophila melanogaster; Drug Resistance; Escherichia coli; Ethyl Methanesulfonate; Flow Cytometry; Genes, Reporter; Gentamicins; Methyl Methanesulfonate; Mitomycin; Mitosis; Mutagenicity Tests; Mutagens; Polymerase Chain Reaction; Recombination, Genetic; Repetitive Sequences, Nucleic Acid; Transgenes

1997
The ability of the Comet assay to discriminate between genotoxins and cytotoxins.
    Mutagenesis, 1998, Volume: 13, Issue:1

    Topics: 4-Nitroquinoline-1-oxide; Aminacrine; Animals; Cell Extracts; Cell Line; Cell Survival; Cytotoxins; DNA; Electrophoresis, Agar Gel; Ethyl Methanesulfonate; Ethylnitrosourea; Glyoxal; Humans; Hydrogen Peroxide; Mitomycin; Mutagens

1998
Investigation of mycobacterial recA function: protein introns in the RecA of pathogenic mycobacteria do not affect competency for homologous recombination.
    Molecular microbiology, 1998, Volume: 29, Issue:5

    Topics: Alleles; Bacterial Proteins; Blotting, Southern; Cell Division; Cloning, Molecular; Ethyl Methanesulfonate; Gene Deletion; Genetic Vectors; Mitomycin; Mutagenesis, Insertional; Mutagens; Mycobacterium smegmatis; Mycobacterium tuberculosis; Phenotype; Protein Splicing; Rec A Recombinases; Recombination, Genetic; Transformation, Bacterial; Ultraviolet Rays

1998
Internal ribosome entry segment-mediated initiation of c-Myc protein synthesis following genotoxic stress.
    The Biochemical journal, 2001, Oct-01, Volume: 359, Issue:Pt 1

    Topics: 5' Untranslated Regions; Blotting, Northern; Blotting, Western; Cell Survival; DNA Damage; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Ethyl Methanesulfonate; HeLa Cells; Humans; Immunosuppressive Agents; Luciferases; Mitogen-Activated Protein Kinases; Mitomycin; p38 Mitogen-Activated Protein Kinases; Peptide Chain Initiation, Translational; Phosphorylation; Precipitin Tests; Protein Biosynthesis; Protein Kinases; Protein Synthesis Inhibitors; Proto-Oncogene Mas; Proto-Oncogene Proteins c-myc; Ribosomes; RNA, Messenger; Sirolimus; TOR Serine-Threonine Kinases; Transcription Factors

2001
Phenotype of FAECB (Facility for Automated Experiments in Cell Biology) Chinese hamster ovary mutants with minimal UV-sensitivity.
    Mutation research, 2001, Nov-01, Volume: 487, Issue:1-2

    Topics: Animals; Cell Division; Cell Survival; CHO Cells; Cricetinae; DNA; DNA Damage; Ethyl Methanesulfonate; Mitomycin; Phenotype; Ultraviolet Rays; X-Rays

2001
Chemotherapeutically induced deletion of expanded triplet repeats.
    Mutation research, 2002, Oct-31, Volume: 508, Issue:1-2

    Topics: Antineoplastic Agents; Cisplatin; Dactinomycin; DNA Repair; Escherichia coli; Ethyl Methanesulfonate; Ethylnitrosourea; Mitomycin; Mutagens; Oxidative Stress; Plasmids; Sequence Deletion; Trinucleotide Repeats; Ultraviolet Rays; X-Rays

2002
Comet assay and flow cytometry analysis of DNA repair in normal and cancer cells treated with known mutagens with different mechanisms of action.
    Teratogenesis, carcinogenesis, and mutagenesis, 2003, Volume: Suppl 2

    Topics: Cell Cycle; Cells, Cultured; Comet Assay; Cross-Linking Reagents; DNA; DNA Damage; DNA Repair; DNA, Neoplasm; Ethyl Methanesulfonate; Flow Cytometry; Humans; Lymphocytes; Micronuclei, Chromosome-Defective; Mitomycin; Mutagens; Neoplasms

2003
Effect of cyanidin 3-O-beta-glucopyranoside on micronucleus induction in cultured human lymphocytes by four different mutagens.
    Environmental and molecular mutagenesis, 2004, Volume: 43, Issue:1

    Topics: Adult; Anthocyanins; Antioxidants; Apoptosis; Cells, Cultured; Colchicine; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Humans; Hydrogen Peroxide; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mitomycin; Mutagens; T-Lymphocytes

2004
Screening for genotoxicity using the DRAG assay: investigation of halogenated environmental contaminants.
    Mutation research, 2004, Sep-12, Volume: 563, Issue:1

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Alkylating Agents; Animals; Biological Assay; Carcinogens; Cell Line; CHO Cells; Cricetinae; DNA Adducts; DNA Repair; Environmental Pollutants; Ethyl Methanesulfonate; Humans; Hydrogen Peroxide; Male; Mitomycin; Molecular Structure; Mutagenicity Tests; Mutagens; Oxidants

2004
[TK locus mutation assay: comparison of L5178Y and TK6 cell lines].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2004, Volume: 35, Issue:5

    Topics: Animals; Cell Line, Tumor; Ethyl Methanesulfonate; Humans; Leukemia L5178; Lymphoma; Methyl Methanesulfonate; Mice; Mitomycin; Mutagenicity Tests; Mutation; Thymidine Kinase

2004
Chemotherapeutic deletion of CTG repeats in lymphoblast cells from DM1 patients.
    Nucleic acids research, 2004, Volume: 32, Issue:21

    Topics: Alleles; Antineoplastic Agents, Alkylating; Cell Line; Doxorubicin; Ethyl Methanesulfonate; Humans; Lymphocytes; Mitomycin; Mitoxantrone; Myotonic Dystrophy; Trinucleotide Repeat Expansion

2004
Effect of sulforaphane on micronucleus induction in cultured human lymphocytes by four different mutagens.
    Environmental and molecular mutagenesis, 2005, Volume: 46, Issue:4

    Topics: Anticarcinogenic Agents; Apoptosis; Cell Division; Cells, Cultured; Ethyl Methanesulfonate; Humans; Hydrogen Peroxide; Isothiocyanates; Lymphocytes; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mitomycin; Mutagens; Phosphatidylinositols; Sulfoxides; Thiocyanates

2005
Comparison of the mutagenic potential of 17 physical and chemical agents analyzed by the flow cytometry mutation assay.
    Mutation research, 2006, Dec-01, Volume: 602, Issue:1-2

    Topics: Animals; CD59 Antigens; CHO Cells; Chromosomes, Human, Pair 11; Cricetinae; Cross-Linking Reagents; DNA Mutational Analysis; Ethyl Methanesulfonate; Flow Cytometry; Humans; Mitomycin; Mutagens; Organometallic Compounds; Radiation, Ionizing; Time Factors

2006
Effect of vanillin on toxicant-induced lethality in the Drosophila melanogaster DNA repair test.
    Environmental and molecular mutagenesis, 2007, Volume: 48, Issue:1

    Topics: Animals; Antimutagenic Agents; Benzaldehydes; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Drosophila melanogaster; Ethyl Methanesulfonate; Ethylnitrosourea; Female; Male; Mitomycin; Mutagens; Recombination, Genetic

2007
Characterization of superoxide-stress sensing recombinant Escherichia coli constructed using promoters for genes zwf and fpr fused to lux operon.
    Applied microbiology and biotechnology, 2007, Volume: 74, Issue:6

    Topics: Aliivibrio fischeri; Bacterial Proteins; Benzyl Viologen; Dose-Response Relationship, Drug; Escherichia coli; Ethyl Methanesulfonate; Gene Expression Regulation, Bacterial; Genes, Bacterial; Mitomycin; Oligonucleotide Array Sequence Analysis; Operon; Paraquat; Plasmids; Promoter Regions, Genetic; Recombinant Fusion Proteins; Superoxides

2007
DNA instability in replicating Huntington's disease lymphoblasts.
    BMC medical genetics, 2009, Feb-11, Volume: 10

    Topics: Cell Division; Cell Line; Cross-Linking Reagents; Ethidium; Ethyl Methanesulfonate; Female; Humans; Huntington Disease; Intercalating Agents; Lymphocytes; Male; Microsatellite Instability; Mitomycin; Mosaicism; Mutation; Trinucleotide Repeat Expansion

2009
Insensitivity of the in vitro cytokinesis-block micronucleus assay with human lymphocytes for the detection of DNA damage present at the start of the cell culture.
    Mutagenesis, 2012, Volume: 27, Issue:6

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Cell Culture Techniques; Cell Nucleus; Cells, Cultured; Comet Assay; Cytokinesis; DNA Damage; Epoxy Compounds; Ethyl Methanesulfonate; Ethylnitrosourea; Female; Humans; Lymphocytes; Male; Methyl Methanesulfonate; Micronucleus Tests; Mitomycin; Mutagenicity Tests; Mutagens

2012
A combination of in vitro comet assay and micronucleus test using human lymphoblastoid TK6 cells.
    Mutagenesis, 2013, Volume: 28, Issue:5

    Topics: Cell Survival; Cells, Cultured; Comet Assay; Cross-Linking Reagents; Cytotoxins; Ethyl Methanesulfonate; Gamma Rays; Humans; Hydrogen Peroxide; Methyl Methanesulfonate; Micronucleus Tests; Mitomycin; Mutagenicity Tests; Mutagens; Octoxynol; Sensitivity and Specificity

2013
Quantitative analysis of γH2AX reveals distinct responses in multiple mouse organs after administration of mitomycin C or ethyl methanesulfonate.
    Mutagenesis, 2018, 12-31, Volume: 33, Issue:5-6

    Topics: Animals; Bone Marrow; DNA Breaks, Double-Stranded; DNA Damage; Ethyl Methanesulfonate; Gene Expression Regulation; Histones; Kidney; Male; Mice; Mitomycin; Mutagens; Phosphorylation; Spleen; Testis

2018
Dosage time affects alkylating agents induced micronuclei in mouse peripheral blood reticulocytes through the function of erythropoietin.
    The Journal of toxicological sciences, 2019, Volume: 44, Issue:4

    Topics: Administration, Metronomic; Alkylating Agents; Animals; Apoptosis; bcl-X Protein; Bone Marrow Cells; Cell Nucleolus; Circadian Rhythm; Cyclophosphamide; Darkness; DNA Damage; Erythropoietin; Ethyl Methanesulfonate; Light; Male; Methylnitrosourea; Mice, Inbred C3H; Mitomycin; Reticulocytes; Time; Vincristine

2019