ethyl methanesulfonate has been researched along with methylnitronitrosoguanidine in 143 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 122 (85.31) | 18.7374 |
| 1990's | 13 (9.09) | 18.2507 |
| 2000's | 6 (4.20) | 29.6817 |
| 2010's | 2 (1.40) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Faulkner, GP; Follett, EA; Pringle, CR; Shirodaria, PV | 1 |
| Galloway, SM; Wolff, S | 1 |
| Sandberg, AA; Shiraishi, Y | 1 |
| Fahrig, R | 1 |
| Nakanishi, Y; Schneider, EL | 1 |
| Fraser, MJ | 1 |
| Nestmann, ER | 1 |
| Liwerant, IJ; Pereira da Silva, LH | 1 |
| Deen, D; Fritz, S; Morrow, J; Prickett, MS; Vernick, D | 1 |
| Iwahara, S; Kuroda, Y; Shibuya, T | 1 |
| Coffino, P; Friedrich, U | 1 |
| Bernstein, C; Bernstein, H; Johns, V | 1 |
| Boling, ME; Kimball, RF; Perdue, SW | 1 |
| Lemontt, JF | 1 |
| Katsuki, M; Otsuji, N; Sekiguchi, M; Yamamoto, Y | 1 |
| Cairns, J; Defais, M; Jeggo, P; Samson, L; Schendel, PF | 1 |
| Hackel, RA; Khan, NA | 1 |
| Griffin, DE; Hill, WE | 1 |
| Caten, CE; Simpson, IN | 1 |
| Breitbart, M; Mason, T; Meyers, J | 1 |
| Awerbuch, TE; Stark, AA | 1 |
| Sharma, VK | 1 |
| Huang, SL | 1 |
| Maizumi, H; Saito, M; Tsutsui, T; Umeda, M | 1 |
| Aron, GM; Battreall, CM; Friedrichs, WE; Reed, JP | 1 |
| Kuwata, T; Suzuki, N | 1 |
| Heddle, JA; Katz, M; Salamone, MF | 1 |
| Hsie, AW; O'Neill, JP; Schenley, RL | 1 |
| Barker, CJ; Rackham, BD | 1 |
| Bellett, AJ; Younghusband, HB | 1 |
| Burg, K; Dallmann, L; Raskó, I; Rétfalvi, T | 1 |
| Amemura, A; Harada, T; Hisamatsu, M | 1 |
| Harris, H; Nelson, RL | 1 |
| Heidelberger, C; Peterson, AR; Peterson, H | 2 |
| Moseley, BE; Sweet, DM | 1 |
| Novel, G; Novel, M | 1 |
| Wild, JR | 1 |
| Roth, R | 1 |
| Pantyukhova, VV; Pekhov, AP; Rudneva, SN | 1 |
| Attardi, G; England, JM; Mitchell, CH | 1 |
| Ahlquist, EF; Fewson, CA; Ritchie, DA | 1 |
| Macgregor, JT; Sacks, LE | 1 |
| Garner, RC; Martin, CN; McDermid, AC | 1 |
| Hannan, MA; Nasim, A | 1 |
| Buchwald, M | 1 |
| Brimer, PA; Couch, DB; Hsie, AW; Machanoff, R; O'Neill, JP; San Sebastian, JR | 1 |
| Hooykaas, PJ; Kester, HC; Klapwijk, PM; RORSCH, A; Schilperoort, RA | 1 |
| Fraenkel, DG; Hillman, JD | 1 |
| Mezger-Freed, L | 1 |
| Sekiguchi, F; Sekiguchi, T; Tomii, S | 1 |
| Kao, FT; Puck, T | 1 |
| Asita, AO; Hayashi, M; Kodama, Y; Matsuoka, A; Sofuni, T; Suzuki, T | 1 |
| Deorukhakar, VV; Murthy, MS | 1 |
| Berger, NA; Berger, SJ; Chatterjee, S; Cheng, MF | 1 |
| Lawrence, CW | 1 |
| Karwan, A; Klein, F; Wintersberger, U | 1 |
| Pattee, PA; Tam, JE | 1 |
| Ivarie, R; Morris, JA | 1 |
| Faustman, EM; Gage, D; Kirby, Z; Varnum, M | 1 |
| Pueyo, C; Roldán-Arjona, T; Ruiz-Rubio, M | 1 |
| Boerner, P; Chuman, L; Rindler, MJ; Saier, MH; U, HS | 1 |
| Murphy, CS; Steinberg, RA | 1 |
| Etkin, S; Kleinberger, T; Lavi, S | 1 |
| Hiwasa, T; Sakiyama, S; Tanigawara, C | 1 |
| Guan, WB; Yao, SN | 1 |
| Kohalmi, SE; Kunz, BA | 1 |
| Lubet, RA; McCarvill, JT; Putman, DL; Schechtman, LM; Schwartz, JL | 1 |
| Loeb, LA; Mita, S; Monnat, RJ | 1 |
| Hooley, P; Shawcross, SG; Strike, P | 1 |
| Karwan, A; Wintersberger, U | 1 |
| Barbé, J; Guerrero, R; Vericat, JA | 2 |
| Perozzi, G; Polakowska, R; Prakash, L | 1 |
| Awerbuch, TE; Lustman, L | 1 |
| Mitchel, RE; Morrison, DP | 1 |
| Deparis, P; Ferrier, V; Grinfeld, S; Jaylet, A; Siboulet, R | 1 |
| Stratford, IJ; Walling, JM | 1 |
| Cheng, SJ | 1 |
| Frosina, G; Laval, F | 1 |
| Kaufman, ER | 1 |
| Christensen, RB; Lawrence, CW; Nisson, PE | 1 |
| Ehling, UH; Mohn, GR; Neuhäuser-Klaus, A; van Zeeland, AA | 1 |
| Bowring, SN; Morris, JG | 1 |
| Dambly-Chaudière, C; Radman, M; Tenenbaum, L; Toman, Z | 1 |
| Afzal, V; Brown-Lindquist, P; Morgan, WF; Schwartz, JL; Weichselbaum, RR; Wolff, S | 1 |
| Malling, HV | 1 |
| Jeggo, PA; Kemp, LM | 1 |
| Donaghue, TP; Frost, P; Kerbel, RS; Liteplo, RG | 1 |
| Carlow, DA; Elliott, BE; Frost, P; Kerbel, RS; Liteplo, R | 1 |
| Barclay, BJ; Haynes, RH; Kunz, BA; Little, JG | 1 |
| Hankinson, O | 1 |
| Dively, C; Gallagher, MM; Kiss, E; Kouri, RE; Lubet, RA; Schechtman, LM | 1 |
| Coleman, KG; Hirschman, J; Kaback, DB; Oeller, PW; Pringle, JR; Ruezinsky, D; Yde Steensma, H | 1 |
| Bauer, E; Cefalu, W; Frost, P; Kerbel, RS; Tartamella-Biondo, R | 1 |
| Behlau, I; Rein, RP; Shanabruch, WG; Walker, GC | 1 |
| Balganesh, M; Setlow, JK | 1 |
| Mahna, SK | 1 |
| Morimoto, K | 1 |
| Ohno, K; Takeshita, K | 1 |
| Adair, GM; Carver, JH; Wandres, DL | 1 |
| Dewdney, RS; Soper, CJ | 1 |
| Dairkee, SH; Glaser, DA | 1 |
| Kaina, B | 1 |
| Ditta, GS; Leong, J; Magazin, M; Moores, JC | 1 |
| Evans, HH; Glazier, KG; Horng, MF; Weber, MC | 1 |
| Nakayasu, M; Rosenkranz, HS; Sakamoto, H; Sugimura, T; Terada, M; Wakabayashi, K | 1 |
| Brenner, S; Castagnoli, L; Cesareni, G | 1 |
| Heard, JT; Matney, TS | 1 |
| Terzi, M; Vergara, R | 1 |
| Abdukhalykova, GF; Andreeva, IV; Skavronskaia, AG | 1 |
| Sager, R; Smith, BL | 1 |
| Barfknecht, TR; Little, JB | 3 |
| Moseley, BE; Tempest, PR | 1 |
| Defais, M; Schendel, PF | 1 |
| Sklar, R; Strauss, B | 1 |
| Hannan, MA; Nasim, A; Nestmann, ER | 1 |
| Gregory, KF; Levadoux, WL; Taylor, A | 1 |
| Hieda-Shiomi, N; Sato, K; Shiomi, T | 2 |
| Li, AP | 1 |
| Abbondandolo, A; Berends, F; Dogliotti, E; Lohman, PH | 1 |
| Meyers, MB; Shin, S; van Diggelen, M; van Diggelen, OP | 1 |
| Goldstein, S; Gupta, RS | 1 |
| Peterson, AR | 1 |
| Goncharova, EI; Rossman, TG | 1 |
| Kohalmi, SE; Kunz, BA; Roche, HM | 1 |
| Mergeay, M; Sadouk, A | 1 |
| Furusho, K; Gerson, SL; Kubota, M; Liu, L; Wakazono, Y | 1 |
| Gustafson, DL; Snead, D; Trotter, BK; Waldren, CA | 1 |
| Berens, RL; Curiel, TJ; Krug, EC; Nash, PB | 1 |
| Furusho, K; Kubota, M; Wakazono, Y | 1 |
| Henson, ES; Karthikeyan, R; Kunz, BA; Kuschak, T; McQueen, SA; Scott, CA; Xiao, W | 1 |
| Ibrahim, SA; O'Sullivan, DJ | 1 |
| Abraham, SK | 1 |
| Barbour, L; Hanna, M; Xiao, W | 1 |
| Arimoto, S; Negishi, T; Okamoto, K; Takahashi, E; Yamanaka, H | 1 |
| Ali, S; Aslam, A; Qadeer, MA; ul-Haq, I | 1 |
| Charron, AJ; Cove, DJ; Khandelwal, A; McDaniel, SF; Perroud, PF; Quatrano, RS | 1 |
| Bultman, J; Fell, JW; Johnson, EA; Lin, G | 1 |
| Bergmann, A; Brynjolfsson, S; Fu, W; Ingthorsson, S; Rolfsson, O; Salehi-Ashtiani, K; Su, Y; Xu, M; Yi, Z | 1 |
1 review(s) available for ethyl methanesulfonate and methylnitronitrosoguanidine
| Article | Year |
|---|---|
Possible epigenetic mechanisms of tumor progression: induction of high-frequency heritable but phenotypically unstable changes in the tumorigenic and metastatic properties of tumor cell populations by 5-azacytidine treatment.
Topics: Animals; Azacitidine; DNA; Ethyl Methanesulfonate; Humans; Mammary Neoplasms, Experimental; Methylation; Methylnitronitrosoguanidine; Models, Genetic; Mutation; Neoplasm Metastasis; Neoplasms; Neoplastic Stem Cells; Phenotype; Stem Cells | 1984 |
142 other study(ies) available for ethyl methanesulfonate and methylnitronitrosoguanidine
| Article | Year |
|---|---|
Respiratory syncytial virus ts mutants and nuclear immunofluorescence.
Topics: Animals; Antigens, Viral; Azacitidine; Cell Line; Cell Nucleus; Cytopathogenic Effect, Viral; Ethyl Methanesulfonate; Fluorouracil; Genetic Complementation Test; Haplorhini; HeLa Cells; Methylnitronitrosoguanidine; Mutagens; Mutation; Respiratory Syncytial Viruses; Temperature; Virus Replication | 1976 |
The relation between chemically induced sister-chromatid exchanges and chromatid breakage.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bleomycin; Cell Line; Chromatids; Chromosome Aberrations; Chromosomes; Cricetinae; Cricetulus; Crossing Over, Genetic; Cyclophosphamide; Doxorubicin; Ethyl Methanesulfonate; Female; Methylnitronitrosoguanidine; Mitomycins; Ovary; X-Rays | 1979 |
Effects of various chemical agents on sister chromatid exchanges, chromosome aberrations, and DNA repair in normal and abnormal human lymphoid cell lines.
Topics: 4-Nitroquinoline-1-oxide; Animals; Cell Line; Cell Survival; Chromosome Aberrations; Crossing Over, Genetic; DNA Repair; Ethyl Methanesulfonate; Humans; Leukemia, Experimental; Lymphocytes; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mitomycins | 1979 |
Evidence that induction and suppression of mutations and recombinations by chemical mutagens in S. cerevisiae during mitosis are jointly correlated.
Topics: 4-Nitroquinoline-1-oxide; Acridine Orange; Chlorophenols; Dinitrofluorobenzene; Drug Interactions; Ethyl Methanesulfonate; Halogenated Diphenyl Ethers; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mitosis; Mutagens; Mutation; Phenyl Ethers; Recombination, Genetic; Saccharomyces cerevisiae; Sodium Nitrite; Triethylenemelamine | 1979 |
In vivo sister-chromatid exchange: a sensitive measure of DNA damage.
Topics: 4-Nitroquinoline-1-oxide; Animals; Bromodeoxyuridine; Caffeine; Chromosomes; Crossing Over, Genetic; Cytarabine; Daunorubicin; DNA; Drug Evaluation, Preclinical; Ethyl Methanesulfonate; Genetic Techniques; Male; Methylnitronitrosoguanidine; Mice; Mice, Inbred C57BL; Mitomycins; Mutagens; X-Rays | 1979 |
Enzymes of Neurospora crassa which attack UV-irradiated DNA.
Topics: Deoxyribonucleases; DNA; Endonucleases; Ethyl Methanesulfonate; Exonucleases; Methylnitronitrosoguanidine; Mutation; Neurospora; Neurospora crassa; Radiation Effects; Ultraviolet Rays | 1975 |
Mutagenesis by nitrosoguanidine, ethyl methanesulfonate, and mutator gene mutH in continuous cultures of Escherichia coli.
Topics: Bacteriological Techniques; DNA Replication; Escherichia coli; Ethyl Methanesulfonate; Genes, Regulator; Genetics, Microbial; Mesylates; Methylnitronitrosoguanidine; Mutagens; Mutation; Nitrosoguanidines; Time Factors | 1975 |
Comparative mutagenic effects of ethyl methane-sulfonate, n-methyl-n'-nitro-n-nitrosoguanidine, ultraviolet radiation and caffeine on Dictyostelium discoideum.
Topics: Caffeine; Dictyostelium; Ethyl Methanesulfonate; Mesylates; Methylnitronitrosoguanidine; Mutagens; Myxomycetes; Nitrosoguanidines; Phenotype; Radiation Effects; Temperature; Ultraviolet Rays | 1975 |
Mutagenesis studies on cultured mammalian cells. The sensitivity of the asparagine-requiring phenotype to several chemical agents.
Topics: Asparagine; Cell Line; Cell Survival; Ethyl Methanesulfonate; Genes; Mesylates; Methylnitronitrosoguanidine; Mutation; Nitrosoguanidines; Phenotype; Quinacrine | 1976 |
Studies on procedure for detecting mutagenicity of chemicals in Chinese hamster DON cells [proceedings].
Topics: Cell Line; Drug Resistance; Ethyl Methanesulfonate; Mesylates; Methods; Methylnitronitrosoguanidine; Mutation; Nitrosoguanidines | 1976 |
Mutagenesis in S49 mouse lymphoma cells: induction of resistance to ouabain, 6-thioguanine, and dibutyryl cyclic AMP.
Topics: Bucladesine; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance; Ethyl Methanesulfonate; Kinetics; Lymphoma; Methylnitronitrosoguanidine; Mutagens; Mutation; Ouabain; Thioguanine | 1977 |
Recombinational repair of alkylation lesions in phage T4. II. Ethyl methanesulfonate.
Topics: Alkylation; Coliphages; DNA Repair; Ethyl Methanesulfonate; Mesylates; Methylnitronitrosoguanidine; Mutation; Recombination, Genetic | 1978 |
Evidence that UV-inducible error-prone repair is absent in Haemophilus influenzae Rd, with a discussion of the relation to error-prone repair of alkylating-agent damage.
Topics: Alkylating Agents; DNA Repair; Ethyl Methanesulfonate; Haemophilus influenzae; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mutagens; Mutation; Nitrogen Mustard Compounds; Nitroso Compounds; Phenotype; Ultraviolet Rays; X-Rays | 1977 |
Mutagenesis of yeast by hydrazine: dependence upon post-treatment cell division.
Topics: Canavanine; Cell Division; Drug Resistance, Microbial; Ethyl Methanesulfonate; Genes; Hydrazines; Hydroxylamines; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mutagens; Mutation; Nitrous Acid; Saccharomyces cerevisiae; Ultraviolet Rays | 1977 |
Escherichia coli gene that controls sensitivity to alkylating agents.
Topics: Alkylating Agents; Conjugation, Genetic; Drug Resistance, Microbial; Escherichia coli; Ethyl Methanesulfonate; Genes; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mitomycins; Mutation; Transduction, Genetic | 1978 |
Pathways of mutagenesis and repair in Escherichia coli exposed to low levels of simple alkylating agents.
Topics: Alkylating Agents; DNA Repair; DNA, Bacterial; Escherichia coli; Ethyl Methanesulfonate; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mutation | 1978 |
Genetic control of invertase formation in Saccharomyces cerevisiae. II. Isolation and characterization of mutants conferring invertase hyperproduction in strain EK-6B carrying the SUC3 gene.
Topics: Enzyme Induction; Ethyl Methanesulfonate; Genes; Genes, Recessive; Genetic Linkage; Methylnitronitrosoguanidine; Mutagens; Mutation; Raffinose; Saccharomyces cerevisiae; Sucrase; Sucrose | 1978 |
In vitro breakage of plasmid DNA by mutagens and pesticides.
Topics: Aldrin; Chlordan; DDT; Dichlorvos; Dieldrin; DNA, Circular; Escherichia coli; Ethyl Methanesulfonate; Heptachlor; Malathion; Methyl Methanesulfonate; Methyl Parathion; Methylnitronitrosoguanidine; Mutagens; Pesticides; Plasmids; Toxaphene | 1978 |
Induced quantitative variation for penicillin titre in clonal populations of Aspergillus nidulans.
Topics: Aspergillus nidulans; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Genetic Variation; Methoxsalen; Methylnitronitrosoguanidine; Mutation; Penicillins | 1979 |
Temperature-sensitive mutations of Saccharomyces cerevisiae with defects in mitochondrial function.
Topics: Ethyl Methanesulfonate; Inositol; Manganese; Methods; Methylnitronitrosoguanidine; Mitochondria; Mutation; Saccharomyces cerevisiae; Species Specificity; Temperature | 1979 |
Plate diffusion assay as a rapid method for dosimetry of mutagens.
Topics: Biological Assay; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Methylnitronitrosoguanidine; Methylnitrosourea; Mutagens; Mutation; Mycotoxins; N-Nitrosopyrrolidine; Nitrosamines; Salmonella typhimurium | 1979 |
Action of alkylating agents on nitrogen fixation by clones of Anabaena doliolum Bharadwaja.
Topics: Alkylating Agents; Clone Cells; Cyanobacteria; Ethyl Methanesulfonate; Methylnitronitrosoguanidine; Nitrogen Fixation | 1977 |
The mutability of the minute loci and sex-linked recessive lethals in Drosophila melanogaster.
Topics: Animals; Crosses, Genetic; Drosophila melanogaster; Ethyl Methanesulfonate; Female; Gene Frequency; Genes, Lethal; Genes, Recessive; Genetic Linkage; Male; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Nitrosomethylurethane; Sex Chromosomes | 1977 |
Comparison of mutagenicity and inducibility of DNA single-strand breaks and chromosome aberrations in cultured mouse cells by potent mutagens.
Topics: 4-Nitroquinoline-1-oxide; Animals; Azaguanine; Cell Line; Centrifugation, Density Gradient; Chromosome Aberrations; DNA, Single-Stranded; Drug Evaluation, Preclinical; Drug Resistance; Ethyl Methanesulfonate; Mechlorethamine; Methylnitronitrosoguanidine; Mice; Mutagens; Mutation | 1977 |
Temperature-sensitive mutants of bacteriophage SH-133 specific for the hydrogen bacterium Pseudomonas facilis: isolation, complementation, and partial characterization.
Topics: Bacteriophages; Ethyl Methanesulfonate; Genes, Viral; Genetic Complementation Test; Methylnitronitrosoguanidine; Mutation; Pseudomonas; Temperature; Ultraviolet Rays; Viral Plaque Assay | 1979 |
Establishment of ultraviolet-resistant cells from the highly sensitive human clonal cell line, RSb.
Topics: Cell Line; Clone Cells; Ethyl Methanesulfonate; Humans; Methylnitronitrosoguanidine; Mutagens; Nitroquinolines; Phenotype; Radiation Tolerance; Ultraviolet Rays | 1979 |
The use of the Salmonella/microsomal assay to determine mutagenicity in paired chemical mixtures.
Topics: Benzopyrenes; Biological Assay; Ethyl Methanesulfonate; Methylnitronitrosoguanidine; Microsomes; Mutagens; Mutation; Salmonella | 1979 |
Cytotoxicity and mutagenicity of alkylating agents in cultured mammalian cells (CHO/HGPRT system): mutagen treatment in the presence or absence of serum.
Topics: Alkylating Agents; Animals; Cell Line; Cell Survival; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Female; Hypoxanthine Phosphoribosyltransferase; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mutagens; Mutation; Nitrosourea Compounds; Ovary | 1979 |
The induction of sister-chromatid exchanges in cultured fish cells (Ameca splendens) by carcinogenic mutagens.
Topics: Animals; Bromodeoxyuridine; Carcinogens; Cell Line; Cricetinae; Crossing Over, Genetic; Ethyl Methanesulfonate; Fibroblasts; Fishes; Humans; Karyotyping; Lymphocytes; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mutation; Sister Chromatid Exchange | 1979 |
Spontaneous, mutagen-induced and adenovirus-induced anchorage independent tumorigenic variants of mouse cells.
Topics: Adenoviruses, Human; Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Culture Media; Ethyl Methanesulfonate; Fibroblasts; Genetic Variation; Methylnitronitrosoguanidine; Mice; Mutagens; Mutation; Phenotype; Polysaccharides; Sepharose | 1979 |
Gene mutation and sister chromatid exchange in Chinese hamster cells.
Topics: Animals; Cell Line; Cell Survival; Cricetinae; Crossing Over, Genetic; Ethyl Methanesulfonate; Female; Genes; Hypoxanthine Phosphoribosyltransferase; Methylnitronitrosoguanidine; Mitomycins; Mutation; Ovary; Sister Chromatid Exchange; X-Rays | 1979 |
Spontaneous mutation of polysaccharide production in Alcaligenes faecalis var. myxogenes 10C3.
Topics: Alcaligenes; Culture Media; Ethyl Methanesulfonate; Methylnitronitrosoguanidine; Mutagens; Mutation; Polysaccharides, Bacterial; Ultraviolet Rays | 1977 |
The detection of mutation in human diploid fibroblasts after mutagen treatment using non-selective cloning and enzyme electrophoresis.
Topics: Clone Cells; Diploidy; Electrophoresis, Starch Gel; Ethyl Methanesulfonate; Fibroblasts; Humans; Methylnitronitrosoguanidine; Mutagens; Mutation | 1978 |
Oncogenesis, mutagenesis, DNA damage, and cytotoxicity in cultured mammalian cells treated with alkylating agents.
Topics: Alkylating Agents; Cell Line; Cell Survival; Cell Transformation, Neoplastic; DNA Repair; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mutagens | 1979 |
The resistance of Micrococcus radiodurans to killing and mutation by agents which damage DNA.
Topics: Escherichia coli; Ethyl Methanesulfonate; Gamma Rays; Hydroxylamines; Light; Methylnitronitrosoguanidine; Micrococcus; Mitomycins; Mutagens; Mutation; Nitrous Acid; Propiolactone; Radiation Genetics; Species Specificity; Ultraviolet Rays | 1976 |
Regulation of beta-glucuronidase synthesis in Escherichia coli K-12: constitutive mutants specifically derepressed for uidA expression.
Topics: Cell-Free System; Chromosome Mapping; Enzyme Repression; Escherichia coli; Ethyl Methanesulfonate; Genes; Genes, Regulator; Glucuronidase; Hexuronic Acids; Methylnitronitrosoguanidine; Mutagens; Mutation; Nitrites; Temperature; Ultraviolet Rays | 1976 |
Enhancement of base pair substitution induced by alkylating mutagens in simulated hyperbaric diving environments.
Topics: 2-Aminopurine; Atmosphere Exposure Chambers; Atmospheric Pressure; Base Sequence; Bromodeoxyuridine; DNA, Bacterial; Ethyl Methanesulfonate; Histidine; Methylnitronitrosoguanidine; Mutagens; Mutation; Nitrites; Salmonella typhimurium; Sodium | 1976 |
Temperature-sensitive yeast mutants defective in meiotic recombination and replication.
Topics: DNA Replication; Ethyl Methanesulfonate; Hot Temperature; Meiosis; Methylnitronitrosoguanidine; Mutation; Recombination, Genetic; Saccharomyces cerevisiae | 1976 |
Mutagenesis in the strains E. coli K-12 with different ability to genetic recombination.
Topics: Alleles; Amino Acids; Arginine; Escherichia coli; Ethyl Methanesulfonate; Genes; Histidine; Leucine; Methylnitronitrosoguanidine; Mitomycins; Mutagens; Mutation; Proline; Recombination, Genetic; Threonine | 1976 |
Isolation of chloramphenicol-resistant variants from a human cell line.
Topics: Cell Line; Chloramphenicol; DNA, Mitochondrial; Drug Resistance; Ethyl Methanesulfonate; Genetic Variation; Leucomycins; Methylnitronitrosoguanidine; Mitochondria; Mutation; Protein Biosynthesis; Virginiamycin | 1975 |
The induction of mutants of Acinetobacter calcoaceticus NCIB8250 and their selection by vancomycin.
Topics: Acinetobacter; Benzyl Alcohols; Carbenicillin; Cycloserine; Ethyl Methanesulfonate; Glutamates; Malates; Mesylates; Methoxsalen; Methylnitronitrosoguanidine; Mutagens; Mutation; Penicillin G; Penicillin Resistance; Penicillin V; Phenylacetates; Radiation Effects; Species Specificity; Succinates; Ultraviolet Rays; Vancomycin | 1975 |
The sporulation system of Bacillus subtilis as the basis of a multi-gene mutagen screening test.
Topics: Acridines; Acriflavine; Bacillus subtilis; Chromosomes, Bacterial; Drug Evaluation, Preclinical; Ethyl Methanesulfonate; Methylnitronitrosoguanidine; Mutagens; Mutation; Spores, Bacterial | 1976 |
Measurement of 'unscheduled' DNA synthesis in HeLa cells by liquid scintillation counting after carcinogen treatment.
Topics: Acetoxyacetylaminofluorene; Aflatoxins; Animals; Benz(a)Anthracenes; Carcinogens; DNA; DNA Repair; Ethyl Methanesulfonate; HeLa Cells; Liver; Methylnitronitrosoguanidine; Mixed Function Oxygenases; Rats; Thymidine | 1977 |
Induction of mutations by chemicals and gamma rays in mutants of yeast refractory to UV-mutagenesis.
Topics: Ascomycota; DNA Repair; Ethyl Methanesulfonate; Gamma Rays; Hydroxylamines; Methylnitronitrosoguanidine; Mutagens; Mutation; Schizosaccharomyces; Ultraviolet Rays | 1977 |
Mutagenesis at the ouabain-resistance locus in human diploid fibroblasts.
Topics: Drug Resistance; Ethyl Methanesulfonate; Fibroblasts; Gene Frequency; Genes; Humans; Methylnitronitrosoguanidine; Mutagens; Mutation; Ouabain; Ultraviolet Rays | 1977 |
A quantitative assay of mutation induction at the hypoxanthine-guanine phosphoribosyl transferase locus in Chinese hamster ovary cells (CHO/HGPRT system): utilization with a variety of mutagenic agents.
Topics: Acridines; Aminacrine; Animals; Cell Line; Dimethylnitrosamine; Drug Evaluation, Preclinical; Ethyl Methanesulfonate; Hypoxanthine Phosphoribosyltransferase; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Mice, Nude; Microsomes, Liver; Mutation; Nitrogen Mustard Compounds; Rats; Ultraviolet Rays; X-Rays | 1977 |
Isolation and characterization of Agrobacterium tumefaciens mutants affected in the utilization of octopine, octopinic acid and lysopine.
Topics: Amino Acids, Dicarboxylic; Arginine; Ethyl Methanesulfonate; Lysine; Methylnitronitrosoguanidine; Mutagens; Mutation; Ornithine; Plant Tumors; Plasmids; Rhizobium; Virulence | 1976 |
Glyceraldehyde 3-phosphate dehydrogenase mutants of Escherichia coli.
Topics: Chromosome Mapping; Crosses, Genetic; Escherichia coli; Ethyl Methanesulfonate; Glyceraldehyde-3-Phosphate Dehydrogenases; Methylnitronitrosoguanidine; Mutagens; Mutation; Temperature; Transduction, Genetic | 1975 |
Mutagenesis of haploid cultured frog cells.
Topics: Acridines; Animals; Anura; Cell Line; Cell Survival; Cells, Cultured; Clone Cells; Diploidy; Ethyl Methanesulfonate; Genotype; Haploidy; Methylnitronitrosoguanidine; Mutagens; Mutation; Phenotype | 1975 |
Reversion of the 8-azaguanine resistant phenotype of variant Chinese hamster cells treated with alkylating agents and 5-brono-2'-deoxyuridine.
Topics: Alkylating Agents; Analysis of Variance; Animals; Azaguanine; Bromodeoxyuridine; Carbon Radioisotopes; Cell Line; Cells, Cultured; Clone Cells; Cricetinae; Culture Media; Drug Resistance; Ethyl Methanesulfonate; Genetic Variation; Hypoxanthine Phosphoribosyltransferase; Lung; Methylnitronitrosoguanidine; Mutation; Phenotype; Probability | 1975 |
Genetic complementation in hybrid cells derived from mutagen-induced mouse clones deficient in HGPRT activity.
Topics: Adenocarcinoma; Animals; Autoradiography; Azaguanine; Cell Line; Cell Survival; Chromosomes; Clone Cells; Ethyl Methanesulfonate; Genes; Genetic Complementation Test; Hybrid Cells; Hypoxanthine Phosphoribosyltransferase; Methylnitronitrosoguanidine; Mice; Mice, Inbred C3H; Mutation; Polyploidy; Temperature; Thioguanine | 1975 |
Mutagenesis and genetic analysis with Chinese hamster auxotrophic cell markers.
Topics: Animals; Bromodeoxyuridine; Cell Line; Cells, Cultured; Cricetinae; Ethyl Methanesulfonate; Female; Humans; Hybridization, Genetic; Karyotyping; Light; Methylnitronitrosoguanidine; Molecular Biology; Mutagens; Mutation; Ovary; Ultraviolet Rays; X-Rays | 1975 |
Micronucleated reticulocyte induction by ethylating agents in mice.
Topics: Alkylating Agents; Animals; Epichlorohydrin; Ethyl Methanesulfonate; Ethylene Dibromide; Ethylnitrosourea; Evaluation Studies as Topic; Male; Methylnitronitrosoguanidine; Mice; Micronucleus Tests; Reticulocytes; Sulfuric Acid Esters | 1992 |
Influence of anoxia and respiratory deficiency on the genotoxicity of some direct-acting alkylating agents in yeast.
Topics: Alkylating Agents; Cell Hypoxia; Cell Survival; Ethyl Methanesulfonate; Ethylnitrosourea; Mesylates; Methylnitronitrosoguanidine; Methylnitrosourea; Oxygen; Saccharomyces cerevisiae | 1991 |
Alkylating agent hypersensitivity in poly(adenosine diphosphate-ribose) polymerase deficient cell lines.
Topics: 4-Nitroquinoline-1-oxide; Alkylating Agents; Animals; Cell Line; Cell Survival; Cricetinae; DNA Repair; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Ethylnitrosourea; Lethal Dose 50; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Poly(ADP-ribose) Polymerases; Sulfuric Acid Esters | 1991 |
Classical mutagenesis techniques.
Topics: Ethyl Methanesulfonate; Genetic Techniques; Methylnitronitrosoguanidine; Mutagenesis; Saccharomyces cerevisiae; Ultraviolet Rays | 1991 |
Pedigree analyses of yeast cells recovering from DNA damage allow assignment of lethal events to individual post-treatment generations.
Topics: DNA Damage; Ethyl Methanesulfonate; Genes, Fungal; Genes, Lethal; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mutagens; Mutation; Nitrous Acid; Probability; Saccharomyces cerevisiae | 1990 |
Characterization and genetic mapping of a mutation affecting apurinic endonuclease activity in Staphylococcus aureus.
Topics: 4-Nitroquinoline-1-oxide; Chromosome Mapping; Chromosomes, Bacterial; Deoxyribonuclease IV (Phage T4-Induced); DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; Endodeoxyribonucleases; Ethyl Methanesulfonate; Genes, Bacterial; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Mutation; Nitrous Acid; Recombination, Genetic; Staphylococcus aureus; Ultraviolet Rays | 1986 |
Activation of a nonexpressed hypoxanthine phosphoribosyltransferase allele in mutant H23 HeLa cells by agents that inhibit DNA methylation.
Topics: Alleles; Azacitidine; Azaserine; Ethyl Methanesulfonate; Genes; HeLa Cells; Humans; Hypoxanthine Phosphoribosyltransferase; Methylation; Methylnitronitrosoguanidine; Mutation; Thioguanine | 1986 |
In vitro developmental toxicity of five direct-acting alkylating agents in rodent embryos: structure-activity patterns.
Topics: Alkylating Agents; Analysis of Variance; Animals; Brain; Dose-Response Relationship, Drug; Embryo, Mammalian; Ethyl Methanesulfonate; Ethylnitrosourea; Female; In Vitro Techniques; Maternal-Fetal Exchange; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Methylnitrosourea; Pregnancy; Rats; Rats, Inbred Strains | 1989 |
Simple method for precise determination of chemical lethality in the L-arabinose resistance test of Salmonella typhimurium.
Topics: 2-Naphthylamine; Arabinose; Biotransformation; Drug Resistance, Microbial; Ethyl Methanesulfonate; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mutagenicity Tests; Mutagens; Salmonella typhimurium | 1989 |
Characterization of chemically and virally transformed variants of Madin-Darby canine kidney (MDCK) epithelial cells.
Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cyclic AMP; Dogs; Epithelial Cells; Epithelium; Ethyl Methanesulfonate; Kidney; Methylnitronitrosoguanidine; Mice; Mice, Nude; Ornithine Decarboxylase | 1985 |
Hotspots for spontaneous and mutagen-induced lesions in regulatory subunit of cyclic AMP-dependent protein kinase in S49 mouse lymphoma cells.
Topics: Animals; Bucladesine; Carrier Proteins; Cell Line; Electrophoresis, Polyacrylamide Gel; Ethyl Methanesulfonate; Intracellular Signaling Peptides and Proteins; Kinetics; Lymphoma; Methylnitronitrosoguanidine; Mice; Mutagens; Mutation; Peptide Fragments; Protein Kinases | 1985 |
Carcinogen-mediated methotrexate resistance and dihydrofolate reductase amplification in Chinese hamster cells.
Topics: Alkylating Agents; Animals; Carcinogens; Cell Cycle; Cell Line; Cricetinae; Dose-Response Relationship, Drug; Drug Resistance; Ethyl Methanesulfonate; Gene Amplification; Methotrexate; Methylnitronitrosoguanidine; Simian virus 40; Tetrahydrofolate Dehydrogenase; Ultraviolet Rays | 1986 |
Defects of cyclic adenosine 3':5'-monophosphate-dependent protein kinases in initiated clones derived from BALB/c 3T3 mouse fibroblasts.
Topics: 4-Nitroquinoline-1-oxide; Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Cyclic AMP; Ethyl Methanesulfonate; Fibroblasts; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Protein Kinases; Tetradecanoylphorbol Acetate | 1987 |
[Mutagenic effects of N-methyl-N-nitro-N-nitrosoguanidine (MNNG) and ethyl methanesulfonate (EMS) on chloroquine resistance in Plasmodium berghei ANKA strain].
Topics: Animals; Chloroquine; Drug Resistance; Ethyl Methanesulfonate; Female; Male; Methylnitronitrosoguanidine; Mice; Mutation; Plasmodium berghei; Serial Passage | 1988 |
Role of neighbouring bases and assessment of strand specificity in ethylmethanesulphonate and N-methyl-N'-nitro-N-nitrosoguanidine mutagenesis in the SUP4-o gene of Saccharomyces cerevisiae.
Topics: Base Sequence; DNA, Fungal; Ethyl Methanesulfonate; Genes, Fungal; Methylnitronitrosoguanidine; Molecular Sequence Data; Mutagens; Mutation; Saccharomyces cerevisiae | 1988 |
Effects of 3-aminobenzamide on the induction of morphologic transformation by diverse compounds in Balb/3T3 cells in vitro.
Topics: Aflatoxin B1; Aflatoxins; Animals; Benzamides; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; Ethyl Methanesulfonate; Kinetics; Methylcholanthrene; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C | 1986 |
Resistance of HeLa cell mitochondrial DNA to mutagenesis by chemical carcinogens.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Base Sequence; DNA Replication; DNA, Mitochondrial; Drug Resistance; Ethyl Methanesulfonate; HeLa Cells; Humans; Methylnitronitrosoguanidine; Mutation | 1988 |
Mutants of Aspergillus nidulans with increased resistance to the alkylating agent, N-methyl-N'-nitro-N-nitrosoguanidine.
Topics: Aspergillus nidulans; Drug Resistance, Microbial; Ethyl Methanesulfonate; Genes, Fungal; Methylnitronitrosoguanidine; Radiation Tolerance; Spores, Fungal; Ultraviolet Rays | 1988 |
Retardation of cell cycle progression in yeast cells recovering from DNA damage: a study at the single cell level.
Topics: Cell Cycle; Cell Nucleus; DNA Damage; DNA Repair; Dose-Response Relationship, Radiation; Ethyl Methanesulfonate; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Nitrous Acid; Saccharomyces cerevisiae | 1987 |
Effect of alkylating agents on the expression of inducible genes of Escherichia coli.
Topics: Alkylating Agents; DNA Damage; Escherichia coli; Ethyl Methanesulfonate; Gene Expression Regulation; Genes, Bacterial; Isopropyl Thiogalactoside; Lac Operon; Methylnitronitrosoguanidine; Sulfuric Acid Esters | 1986 |
Alkylation mutagenesis in Saccharomyces cerevisiae: lack of evidence for an adaptive response.
Topics: Adaptation, Physiological; Alkylation; Cell Cycle; Cycloheximide; DNA Repair; Ethyl Methanesulfonate; Genes, Fungal; Methylnitronitrosoguanidine; Mutation; Saccharomyces cerevisiae | 1986 |
A mathematical model for determining minimal inhibitory concentrations (MICs) via diffusion assays.
Topics: Diffusion; Ethyl Methanesulfonate; Mathematics; Methylnitronitrosoguanidine; Microbial Sensitivity Tests; Models, Biological | 1987 |
Inducible DNA-repair systems in yeast: competition for lesions.
Topics: DNA Damage; DNA Repair; Ethyl Methanesulfonate; Ethylnitrosourea; Gamma Rays; Methylnitronitrosoguanidine; Methylnitrosourea; Mutation; Saccharomyces cerevisiae; Ultraviolet Rays | 1987 |
A new micronucleus test using peripheral blood erythrocytes of the newt Pleurodeles waltl to detect mutagens in fresh-water pollution.
Topics: Animals; Benzo(a)pyrene; Cell Nucleus; Diethylstilbestrol; Dose-Response Relationship, Drug; Erythrocytes; Ethyl Methanesulfonate; Methylnitronitrosoguanidine; Mutagenicity Tests; Pleurodeles; Salamandridae; Water Pollutants | 1986 |
Chemosensitization by monofunctional alkylating agents.
Topics: Animals; Antineoplastic Agents; Cell Line; Cisplatin; Cricetinae; Drug Synergism; Ethyl Methanesulfonate; In Vitro Techniques; Melphalan; Methyl Methanesulfonate; Methylnitronitrosoguanidine | 1986 |
[Micronucleus test in cultured cells--preliminary study].
Topics: Animals; Benzo(a)pyrene; Bone Marrow; Cells, Cultured; Cricetinae; Ethyl Methanesulfonate; Male; Mesocricetus; Methylnitronitrosoguanidine; Mice; Mutagenicity Tests | 1986 |
The O6-methylguanine-DNA-methyltransferase activity of rat hepatoma cells is increased after a single exposure to alkylating agents.
Topics: Alkylating Agents; Animals; Cell Line; Ethyl Methanesulfonate; Liver Neoplasms, Experimental; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Rats | 1987 |
Reversion analysis of mutations induced by 5-bromodeoxyuridine mutagenesis in mammalian cells.
Topics: Animals; Bromodeoxyuridine; Cell Line; Cricetinae; Deoxyribonucleotides; DNA Replication; Ethyl Methanesulfonate; Hypoxanthine Phosphoribosyltransferase; Melanoma; Mesocricetus; Methylnitronitrosoguanidine; Mutation | 1985 |
UV and chemical mutagenesis in rev7 mutants of yeast.
Topics: Alleles; Diploidy; Ethyl Methanesulfonate; Genes, Fungal; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mutagens; Mutation; Saccharomyces cerevisiae; Ultraviolet Rays | 1985 |
Quantitative comparison of genetic effects of ethylating agents on the basis of DNA adduct formation. Use of O6-ethylguanine as molecular dosimeter for extrapolation from cells in culture to the mouse.
Topics: Alkylating Agents; Animals; Cell Line; Cells, Cultured; Cricetinae; Cricetulus; DNA; Environmental Exposure; Escherichia coli; Ethyl Methanesulfonate; Ethylnitrosourea; Guanine; Lung; Methylnitronitrosoguanidine; Mice; Mutation; Structure-Activity Relationship; Sulfuric Acid Esters | 1985 |
Mutagenesis of Clostridium acetobutylicum.
Topics: Clostridium; DNA Repair; Ethyl Methanesulfonate; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Mutation | 1985 |
A system for detection of genetic and epigenetic alterations in Escherichia coli induced by DNA-damaging agents.
Topics: Aflatoxin B1; Aflatoxins; Antibiotics, Antineoplastic; Carcinogens; DNA Repair; Escherichia coli; Ethyl Methanesulfonate; Galactokinase; Gamma Rays; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Mutagenicity Tests; Mutagens; Recombination, Genetic; Ultraviolet Rays | 1985 |
Comutagenic effects of 3-aminobenzamide in Chinese hamster ovary cells.
Topics: Animals; Benzamides; Cell Survival; Cells, Cultured; Chromosome Aberrations; Cricetinae; Cricetulus; DNA; Drug Synergism; Ethyl Methanesulfonate; Female; Methylnitronitrosoguanidine; Mutagens; Mutation; Ovary | 1985 |
Hydroxylamine-induced purple mutants (ad-3) in Neurospora crassa. II. Identification of genetic alteration at the molecular level.
Topics: Base Sequence; Chromosome Mapping; Ethyl Methanesulfonate; Genetic Complementation Test; Hydroxylamines; Methylnitronitrosoguanidine; Mutagens; Mutation; Neurospora; Neurospora crassa; Nitrogen Mustard Compounds; Nitrous Acid | 1971 |
Discriminated induction of SOS functions in Escherichia coli by alkylating agents.
Topics: Alkylating Agents; Bacteriophage lambda; Bleomycin; Cell Division; DNA, Bacterial; Escherichia coli; Ethyl Methanesulfonate; Methylnitronitrosoguanidine; Oxygen Consumption; Rec A Recombinases; Sulfuric Acid Esters; Ultraviolet Rays; Virus Activation | 1983 |
X-ray-sensitive mutants of Chinese hamster ovary cell line. Isolation and cross-sensitivity to other DNA-damaging agents.
Topics: Animals; Bleomycin; Cell Line; Cricetinae; Cricetulus; DNA Repair; Ethyl Methanesulfonate; Female; Methods; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mutation; Ovary; Ultraviolet Rays; X-Rays | 1983 |
Selection of strongly immunogenic "tum-" variants from tumors at high frequency using 5-azacytidine.
Topics: 5-Methylcytosine; Animals; Antigens, Neoplasm; Azacitidine; Cell Transformation, Neoplastic; Cytosine; DNA; Ethyl Methanesulfonate; Mammary Neoplasms, Experimental; Mast-Cell Sarcoma; Methylnitronitrosoguanidine; Mice; Mice, Inbred A; Mice, Inbred DBA; Mice, Nude; Mutagens; Neoplasm Transplantation; Phenotype | 1984 |
Genetic and biochemical consequences of thymidylate stress.
Topics: Chromosome Aberrations; DNA Repair; DNA, Fungal; DNA, Mitochondrial; Ethyl Methanesulfonate; Floxuridine; Methotrexate; Methylnitronitrosoguanidine; Models, Biological; Mutation; Recombination, Genetic; Saccharomyces cerevisiae; Sister Chromatid Exchange; Sulfanilamides; Thymidine Monophosphate; Thymine Nucleotides | 1982 |
Evidence that Benzo(a) pyrene-resistant, aryl hydrocarbon hydroxylase-deficient variants of mouse hepatoma line, Hepa-1, are mutational in origin.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzopyrenes; Cell Line; Drug Resistance; Ethyl Methanesulfonate; Genetic Variation; Liver Neoplasms, Experimental; Methylnitronitrosoguanidine; Mice; Mutagens; Mutation; Phenotype | 1981 |
Induction of neoplastic transformation and DNA single-strand breaks in C3H/10T1/2 clone 8 cells by polycyclic hydrocarbons and alkylating agents.
Topics: Alkylating Agents; Animals; Benzo(a)pyrene; Benzopyrenes; Cell Survival; Cell Transformation, Neoplastic; Clone Cells; DNA Repair; Drug Evaluation, Preclinical; Ethyl Methanesulfonate; Methylcholanthrene; Methylnitronitrosoguanidine; Mice; Polycyclic Compounds | 1983 |
Temperature-sensitive lethal mutations on yeast chromosome I appear to define only a small number of genes.
Topics: Chromosome Mapping; Chromosomes; Crosses, Genetic; Diploidy; Ethyl Methanesulfonate; Genes, Fungal; Genes, Lethal; Genetic Complementation Test; Genotype; Haploidy; Methylnitronitrosoguanidine; Saccharomyces cerevisiae; Temperature | 1984 |
Mutagen treatment as a means for selecting immunogenic variants from otherwise poorly immunogenic malignant murine tumors.
Topics: Adenocarcinoma; Animals; Ethyl Methanesulfonate; Mammary Neoplasms, Experimental; Mast-Cell Sarcoma; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Mutagens; Ouabain; Thioguanine | 1983 |
Mutagenesis, by methylating and ethylating agents, in mutH, mutL, mutS, and uvrD mutants of Salmonella typhimurium LT2.
Topics: 4-Nitroquinoline-1-oxide; Alkylating Agents; DNA Repair; Ethyl Methanesulfonate; Genes, Bacterial; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Methylnitrosourea; Models, Genetic; Mutagens; Mutation; Recombination, Genetic; Salmonella typhimurium; Ultraviolet Rays | 1983 |
Prophage induction in Haemophilus influenzae and its relationship to mutation by chemical and physical agents.
Topics: Bacteriophages; Ethyl Methanesulfonate; Haemophilus influenzae; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Mutagens; Mutation; Ultraviolet Rays; Virus Activation | 1984 |
Transfection assay test system: assay of four chemical mutagens.
Topics: Bacillus subtilis; Bacteriophages; DNA, Viral; Ethyl Methanesulfonate; Hydroxylamine; Hydroxylamines; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mutagenicity Tests; Mutagens; Transfection | 1984 |
Proliferative kinetics and chemical-induced sister chromatid exchanges in human lymphocyte cultures.
Topics: 4-Nitroquinoline-1-oxide; Cell Cycle; Cell Division; Cells, Cultured; DNA Repair; DNA Replication; Ethyl Methanesulfonate; Humans; Lymphocytes; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Nitrosourea Compounds; Sister Chromatid Exchange | 1984 |
Patients with tuberous sclerosis have fibroblasts with normal limits for growth characteristics and sensitivities to DNA alkylating agents.
Topics: 4-Nitroquinoline-1-oxide; Adolescent; Adult; Cell Division; Cell Survival; Cells, Cultured; Child; DNA Repair; Ethyl Methanesulfonate; Fibroblasts; Humans; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Skin; Tuberous Sclerosis | 1984 |
Mutagenicity testing in mammalian cells. II. Validation of multiple drug-resistance markers having practical application for screening potential mutagens.
Topics: 4-Nitroquinoline-1-oxide; Adenine; Adenine Phosphoribosyltransferase; Animals; Benzopyrenes; Biotransformation; Cricetinae; Cricetulus; Dimethylnitrosamine; Drug Resistance; Ethyl Methanesulfonate; Floxuridine; Genetic Markers; Methylnitronitrosoguanidine; Microsomes, Liver; Mutagenicity Tests; Ouabain; Pentosyltransferases; Rats; Thioguanine; Thymidine Kinase | 1980 |
A mutagenesis-enhancing activity of 12-O-tetradecanoylphorbol 13-acetate detected in Chinese hamster ovary cells.
Topics: Animals; Cells, Cultured; Chromosome Aberrations; Cricetinae; Cricetulus; Drug Synergism; Ethyl Methanesulfonate; Female; Methylnitronitrosoguanidine; Mutation; Ovary; Phorbols; Sister Chromatid Exchange; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1984 |
A mutagen-testing assay based on heterogeneity in diameter and integrated optical density of mammalian cell colonies.
Topics: Aminacrine; Animals; Cell Division; Cell Line; Cell Survival; Clone Cells; Cricetinae; Cricetulus; Cyclophosphamide; Dimethyl Sulfoxide; Ethyl Methanesulfonate; Female; Methylnitronitrosoguanidine; Mutagenicity Tests; Mutagens; Mutation; Nitrogen Mustard Compounds; Ovary; Urethane | 1984 |
Cross-resistance studies with V79 Chinese hamster cells adapted to the mutagenic or clastogenic effect of N-methyl-N'-nitro-N-nitrosoguanidine.
Topics: Animals; Cell Line; Cell Survival; Cricetinae; Cricetulus; Drug Resistance; Ethyl Methanesulfonate; Ethylnitrosourea; Lung; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Methylnitrosourea; Mutagens; Thioguanine; Ultraviolet Rays | 1983 |
Cloning of genes involved in the biosynthesis of pseudobactin, a high-affinity iron transport agent of a plant growth-promoting Pseudomonas strain.
Topics: Cloning, Molecular; DNA, Bacterial; Ethyl Methanesulfonate; Genes, Bacterial; Genetic Complementation Test; Ionophores; Methylnitronitrosoguanidine; Mutation; Oligopeptides; Plasmids; Pseudomonas; Ultraviolet Rays | 1984 |
Isolation and characterization of BHK cells sensitive to ionizing radiation and alkylating agents.
Topics: Alkylating Agents; Animals; Cell Line; Cell Survival; Cricetinae; Dose-Response Relationship, Drug; Drug Tolerance; Ethyl Methanesulfonate; Kidney; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Radiation Tolerance | 1984 |
Potent mutagenic activity of nitropyrenes on Chinese hamster lung cells with diphtheria toxin resistance as a selective marker.
Topics: Animals; Biotransformation; Cells, Cultured; Cricetinae; Cricetulus; Diphtheria Toxin; Ethyl Methanesulfonate; Lung; Methylnitronitrosoguanidine; Mutagenicity Tests; Mutagens; Pyrenes; Salmonella typhimurium | 1982 |
The plasmid as a tool for plasmid genetics. I. Fine structure of the beta-lactamase gene.
Topics: Base Sequence; beta-Lactamases; Cloning, Molecular; Escherichia coli; Ethyl Methanesulfonate; Genes; Genotype; Methylnitronitrosoguanidine; Mutation; Plasmids; Ultraviolet Rays | 1982 |
Requirement of a partially diploid donor for the chemical induction of mutations in transforming DNA.
Topics: 4-Nitroquinoline-1-oxide; Bacillus subtilis; DNA Replication; DNA, Bacterial; Ethyl Methanesulfonate; Methylnitronitrosoguanidine; Mutagens; Mutation; Quinacrine; Transformation, Bacterial | 1980 |
Studies of mutagenicity on quiescent and proliferating hamster cell populations.
Topics: 4-Nitroquinoline-1-oxide; Animals; Bromodeoxyuridine; Cell Cycle; Cell Division; Cell Line; Cricetinae; Ethyl Methanesulfonate; Histidinol; Interphase; Methylnitronitrosoguanidine; Mutagens; Time Factors | 1980 |
[Relationship between the presence of plasmid pKM101 and the frequency of spontaneous and induced mutations of different kinds].
Topics: 4-Nitroquinoline-1-oxide; Ethyl Methanesulfonate; Methylnitronitrosoguanidine; Mutagens; Mutation; Organic Chemicals; Plasmids; Salmonella typhimurium; Ultraviolet Rays | 1980 |
Multistep origin of tumor-forming ability in Chinese hamster embryo fibroblast cells.
Topics: 4-Nitroquinoline-1-oxide; Animals; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Cricetulus; Culture Media; Embryo, Mammalian; Ethyl Methanesulfonate; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Mice, Nude; Mutation; Neoplasms, Experimental; Phenotype; Whole-Body Irradiation | 1982 |
Abnormal sensitivity of skin fibroblasts from familial polyposis patients to DNA alkylating agents.
Topics: 4-Nitroquinoline-1-oxide; Alkylating Agents; Cell Survival; DNA; Ethyl Methanesulfonate; Fibroblasts; Humans; Intestinal Polyps; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Skin | 1982 |
Hypersensitivity of ataxia telangiectasia skin fibroblasts to DNA alkylating agents.
Topics: 4-Nitroquinoline-1-oxide; Alkylating Agents; Ataxia Telangiectasia; Cell Line; Cell Survival; Ethyl Methanesulfonate; Fibroblasts; Humans; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Reference Values; Skin | 1982 |
Survival of hereditary retinoblastoma human skin fibroblasts after treatment with DNA-damaging chemicals.
Topics: 4-Nitroquinoline-1-oxide; Alkylating Agents; Cell Survival; Cells, Cultured; Ethyl Methanesulfonate; Eye Neoplasms; Fibroblasts; Humans; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Retinoblastoma; Skin | 1982 |
Defective excision repair in a mutant of Micrococcus radiodurans hypermutable by some monofunctional alkylating agents.
Topics: DNA Repair; Drug Resistance, Microbial; Ethyl Methanesulfonate; Genes, Lethal; Hydroxylamines; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Micrococcus; Mitomycins; Mutagens; Mutation; Nitrous Acid | 1980 |
The role of umuC gene product in mutagenesis by simple alkylating agents.
Topics: Alkylating Agents; DNA Repair; DNA, Bacterial; Dose-Response Relationship, Drug; Escherichia coli; Ethyl Methanesulfonate; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mutagens; Mutation; Ultraviolet Rays | 1980 |
Role of the uvrE gene product and of inducible O6-methylguanine removal in the induction of mutations by N-methyl-N'-nitro-N-nitrosoguanidine in Escherichia coli.
Topics: Chloramphenicol; DNA Repair; DNA, Bacterial; Dose-Response Relationship, Drug; Escherichia coli; Ethyl Methanesulfonate; Guanine; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mutation; Protein Biosynthesis; Ultraviolet Rays | 1980 |
Pure and mosaic clones--a reflection of differences in mechanisms of mutagenesis by different agents in Saccharomyces cerevisiae.
Topics: DNA Repair; DNA Replication; Ethyl Methanesulfonate; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mosaicism; Mutation; Nitrous Acid; Saccharomyces cerevisiae | 1981 |
Sequential cold-sensitive mutations in Aspergillus fumigatus. II. Analysis by the parasexual cycle.
Topics: Aspergillus fumigatus; Cold Temperature; Diploidy; Ethyl Methanesulfonate; Methylnitronitrosoguanidine; Mutagens; Mutation; Recombination, Genetic; Ultraviolet Rays | 1981 |
A novel mutant of mouse lymphoma cells sensitive to alkylating agents and caffeine.
Topics: Alkylating Agents; Animals; Caffeine; Cell Survival; Ethyl Methanesulfonate; Leukemia L5178; Leukemia, Experimental; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mice; Mitomycins; Mutagenicity Tests; Mutagens; Mutation; Ultraviolet Rays | 1982 |
Isolation of UV-sensitive mutants of mouse L5178Y cells by a cell suspension spotting method.
Topics: Animals; Cell Division; Clone Cells; Ethyl Methanesulfonate; Genetic Complementation Test; Leukemia L5178; Leukemia, Experimental; Methods; Methylnitronitrosoguanidine; Mice; Mutation; Ultraviolet Rays | 1982 |
Simplification of the CHO/HGPRT mutation assay through the growth of Chinese hamster ovary cells as unattached cultures.
Topics: Animals; Cell Line; Cricetinae; Cricetulus; Culture Techniques; Ethyl Methanesulfonate; Female; Hypoxanthine Phosphoribosyltransferase; Methylnitronitrosoguanidine; Mutagenicity Tests; Mutagens; Ovary | 1981 |
Molecular dosimetry of DNA damage caused by alkylation. I. Single-strand breaks induced by ethylating agents in cultured mammalian cells in relation to survival.
Topics: Alkylating Agents; Animals; Cell Line; Cell Survival; Cricetinae; Cricetulus; DNA; DNA Repair; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Ethylnitrosourea; Female; Hydrogen-Ion Concentration; Methylnitronitrosoguanidine; Ovary; Sulfuric Acid Esters; Time Factors | 1982 |
Isolation of somatic cell mutants with specified alterations in hypoxanthine phosphoribosyltransferase.
Topics: Animals; Azaguanine; Cell Line; Drug Resistance; Ethyl Methanesulfonate; Genes; Hypoxanthine Phosphoribosyltransferase; Methylnitronitrosoguanidine; Mice; Thioguanine | 1980 |
Diphtheria toxin resistance in human fibroblast cell strains from normal and cancer-prone individuals.
Topics: Anemia, Aplastic; Cell Line; Diphtheria Toxin; Dose-Response Relationship, Drug; Drug Resistance; Dwarfism; Ethyl Methanesulfonate; Fanconi Anemia; Humans; Methylnitronitrosoguanidine; Mutation; Photosensitivity Disorders; Syndrome; Xeroderma Pigmentosum | 1980 |
DNA synthesis, mutagenesis, DNA damage, and cytotoxicity in cultured mammalian cells treated with alkylating agents.
Topics: Alkylating Agents; Animals; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; DNA; DNA Repair; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mice; Mutation | 1980 |
A role for metallothionein and zinc in spontaneous mutagenesis.
Topics: Animals; Cadmium; Cell Line; Chlorides; Cricetinae; Cricetulus; Drug Resistance; Ethyl Methanesulfonate; Metallothionein; Methylnitronitrosoguanidine; Mutagenicity Tests; Mutation; Transfection; Zinc Compounds | 1994 |
Elevated intracellular dCTP levels reduce the induction of GC-->AT transitions in yeast by ethyl methanesulfonate or N-methyl-N'-nitro-N- nitrosoguanidine but increase alkylation-induced GC-->CG transversions.
Topics: Alkylation; Base Sequence; Deoxycytosine Nucleotides; DNA Mutational Analysis; DNA Repair; DNA Replication; DNA, Fungal; Ethyl Methanesulfonate; Genes, Fungal; Genes, Suppressor; Guanine; Methylnitronitrosoguanidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutagens; Nucleic Acid Heteroduplexes; Point Mutation; Saccharomyces cerevisiae; Thymine; Thymine Nucleotides | 1993 |
Chromosome mapping in Alcaligenes eutrophus CH34.
Topics: Alcaligenes; Chromosome Mapping; Chromosomes, Bacterial; Conjugation, Genetic; Ethyl Methanesulfonate; Genetic Linkage; Methylnitronitrosoguanidine; Mutagenesis; Plasmids; Temperature | 1993 |
Thymidine kinase deficient cells with decreased TTP pools are hypersensitive to DNA alkylating agents.
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Cell Survival; Ethyl Methanesulfonate; Guanine; HL-60 Cells; Humans; Hypoxanthine Phosphoribosyltransferase; Leukemia, T-Cell; Methylnitronitrosoguanidine; Methyltransferases; Mutagenesis; Mutagens; O(6)-Methylguanine-DNA Methyltransferase; Thymidine Kinase; Thymine Nucleotides; Tumor Cells, Cultured | 1996 |
Expression of human O6-methyl guanine methyl transferase (MGMT) in post replication repair (PRR) deficient CHO-UV-1 cells: compensation for hypersensitivity to methylating and ethylating agents but not to mitomycin C.
Topics: Alkylating Agents; Animals; CHO Cells; Cricetinae; DNA Methylation; DNA Repair; Ethyl Methanesulfonate; Humans; Methylnitronitrosoguanidine; Methyltransferases; Mitomycin; O(6)-Methylguanine-DNA Methyltransferase | 1997 |
Selection and characterization of Toxoplasma gondii mutants resistant to artemisinin.
Topics: Animals; Antimalarials; Antiprotozoal Agents; Artemether; Artemisinins; Drug Resistance; Ethyl Methanesulfonate; Female; Humans; Methylnitronitrosoguanidine; Mice; Mice, Inbred ICR; Mutagenesis; Sesquiterpenes; Toxoplasma; Toxoplasmosis, Animal | 1998 |
Increased cell killing and mutagenecity by DNA alkylating agents in cells with decreased TTP pools.
Topics: Alkylating Agents; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethyl Methanesulfonate; HL-60 Cells; Humans; Hypoxanthine Phosphoribosyltransferase; Kinetics; Methylnitronitrosoguanidine; Mutagens; Quinazolines; Thiophenes; Thymidylate Synthase; Thymine Nucleotides | 1998 |
Defects in base excision repair combined with elevated intracellular dCTP levels dramatically reduce mutation induction in yeast by ethyl methanesulfonate and N-methyl-N'-nitro-N-nitrosoguanidine.
Topics: Alkylating Agents; Alkylation; Carbon-Oxygen Lyases; Deoxycytosine Nucleotides; Deoxyribonuclease IV (Phage T4-Induced); DNA Adducts; DNA Damage; DNA Glycosylases; DNA Ligases; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; DNA, Fungal; Ethyl Methanesulfonate; Fungal Proteins; Genes, Suppressor; Intracellular Fluid; Methylnitronitrosoguanidine; Mutagenesis; N-Glycosyl Hydrolases; Saccharomyces cerevisiae | 1998 |
Use of chemical mutagenesis for the isolation of food grade beta-galactosidase overproducing mutants of bifidobacteria, lactobacilli and Streptococcus thermophilus.
Topics: beta-Galactosidase; Bifidobacterium; DNA Fingerprinting; Ethyl Methanesulfonate; Humans; Lactobacillus; Lactose Intolerance; Methylnitronitrosoguanidine; Mutagenesis; Mutagens; Polymerase Chain Reaction; Streptococcus | 2000 |
Anti-genotoxicity of trans-anethole and eugenol in mice.
Topics: Allylbenzene Derivatives; Animals; Anisoles; Bone Marrow; Cyclophosphamide; Dose-Response Relationship, Drug; Erythrocytes; Ethyl Methanesulfonate; Eugenol; Flavoring Agents; Injections, Intraperitoneal; Male; Methylnitronitrosoguanidine; Mice; Micronucleus Tests; Mutagenicity Tests; Mutagens; Procarbazine; Urethane | 2001 |
Mutagenesis.
Topics: 4-Nitroquinoline-1-oxide; Aminacrine; Ethyl Methanesulfonate; Genes, Fungal; Methylnitronitrosoguanidine; Mutagenesis; Mutagens; Mycology; Nitrogen Mustard Compounds; Quinolones; Saccharomyces cerevisiae; Ultraviolet Rays | 2006 |
Involvement of the drug efflux protein TolC in mutagenicity induced by MNNG or Trp-P-2.
Topics: Bacterial Outer Membrane Proteins; Biological Transport; Carbolines; Escherichia coli; Escherichia coli Proteins; Ethyl Methanesulfonate; Gene Deletion; Gene Expression; Genetic Complementation Test; Membrane Transport Proteins; Methylnitronitrosoguanidine; Mutagenicity Tests; Mutagens | 2006 |
Characterization of a Saccharomyces cerevisiae mutant with enhanced production of beta-D-fructofuranosidase.
Topics: beta-Fructofuranosidase; Ethyl Methanesulfonate; Fermentation; Gene Expression Regulation, Fungal; Hydrogen-Ion Concentration; Kinetics; Methylnitronitrosoguanidine; Mutation; Saccharomyces cerevisiae; Sucrose; Ultraviolet Rays | 2008 |
Chemical and UV mutagenesis of spores and protonemal tissue from the moss Physcomitrella patens.
Topics: Bryopsida; Ethyl Methanesulfonate; Methylnitronitrosoguanidine; Mutagenesis; Mutagens; Spores; Ultraviolet Rays | 2009 |
Genetic manipulation of Xanthophyllomyces dendrorhous and Phaffia rhodozyma.
Topics: Basidiomycota; Ethyl Methanesulfonate; Gene Knockout Techniques; Genetic Engineering; Genetic Vectors; Genome, Fungal; Homologous Recombination; Methylnitronitrosoguanidine; Mutation; Ultraviolet Rays; Xanthophylls | 2012 |
Chemical Mutagenesis and Fluorescence-Based High-Throughput Screening for Enhanced Accumulation of Carotenoids in a Model Marine Diatom Phaeodactylum tricornutum.
Topics: Aquatic Organisms; Carotenoids; Chlorophyll; Chlorophyll A; Chromatography, Liquid; Diatoms; Ethyl Methanesulfonate; Fluorescence; High-Throughput Screening Assays; Lipid Metabolism; Lipids; Metabolic Networks and Pathways; Methylnitronitrosoguanidine; Mutagenesis | 2018 |