ethyl methanesulfonate has been researched along with methyl methanesulfonate in 191 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 105 (54.97) | 18.7374 |
1990's | 52 (27.23) | 18.2507 |
2000's | 20 (10.47) | 29.6817 |
2010's | 14 (7.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Swietlińska, Z; Zaborowska, D; Zuk, J | 1 |
Sandberg, AA; Shiraishi, Y | 1 |
Biber, UP; Graf, U; Vogel, E; Würgler, FE | 1 |
Fahrig, R | 2 |
Ciarrocchi, G; Jose, JG; Linn, S | 1 |
Castellino, S; de Carneri, I; Lorenzetti, R; Ravenna, L | 1 |
Guertin, M; Mamet-Bratley, MD | 1 |
Merrifield, RK; Shooter, KV | 1 |
Karska-Wysocki, B; Thibodeau, L; Verly, WG | 1 |
Cumming, RB; Owens, JG; Sega, GA | 1 |
Karska-Wysocki, B; Mamet-Bratley, MD; Verly, WG | 1 |
Arnold, DW; Calandra, JC; Kennedy, GL; keplinger, ML | 1 |
Miglani, GS; Parkash, R | 1 |
Arlett, CF; Cole, J | 1 |
Hoppe, H; Liber, HL; Skopeck, TR; Thilly, WG | 1 |
Couch, DB; Forbes, NL; Hsie, AW | 1 |
Heiderstädt, R; Schneider, J; Schreiber, D; Warzok, R | 1 |
Boling, ME; Kimball, RF; Perdue, SW | 1 |
Lemontt, JF | 1 |
Bhattacharya, PK; Kubinski, H; Kubinski, ZO; Morin, NR; Zeldin, PE | 1 |
Katsuki, M; Otsuji, N; Sekiguchi, M; Yamamoto, Y | 1 |
Cairns, J; Defais, M; Jeggo, P; Samson, L; Schendel, PF | 1 |
Griffin, DE; Hill, WE | 1 |
Brychcy, T; Nasim, A | 1 |
Huang, SL | 1 |
Hsie, AW; O'Neill, JP; Schenley, RL | 1 |
Barker, CJ; Rackham, BD | 1 |
Cumming, RB; Sega, GA; Sotomayor, RE | 1 |
Benz, RD; Heddle, JA; Lue, CB; Saunders, EF | 1 |
Legator, MS; Truong, L; Ward, JB | 1 |
Heidelberger, C; Peterson, AR; Peterson, H | 1 |
Ripley, LS | 1 |
Stetka, DG; Wolff, S | 2 |
Arlett, CF; Cole, J; Green, MH | 1 |
MacNaughton, AW; Winder, FG | 1 |
Ehrenberg, L; Hussain, S | 1 |
Fox, M | 1 |
Barale, R; Baroncelli, S; Bauer, C; Bronzetti, G; Cammellini, A; Cercignani, G; Cinci, A; Corsi, C; Leporini, C; Loprieno, N; Nieri, R; Nozzolini, M; Rossi, AM; Serra, C | 1 |
Arlett, CF; Colella, CM; Harcourt, SA; Lehmann, AR; Turnbull, D | 1 |
Kojima, H; Konishi, H; Kuroda, Y | 1 |
Blonsky, KS; Lee, GS; Morgan, AR; Savage, EA; Van On, DL; von Borstel, RC | 1 |
Dearfield, KL; Harrington-Brock, K; Huston, J; Moore, MM; Parker, L | 1 |
Link, A; Tempel, K | 1 |
Baranowska, H; Zuk, J | 1 |
Casciano, DA; Domon, OE; Kodell, RL; McGarrity, LJ; Morris, SM | 1 |
Berger, NA; Berger, SJ; Chatterjee, S; Cheng, MF | 1 |
Amara, FM; McKenna, PG; Thompson, CC; Ward, PE; Wilkinson, YA | 1 |
Brown, AG; Caspary, WJ; Cattanach, P; Edwards, I; McBride, D; McGregor, D; Riach, C; Shepherd, W | 1 |
Albertini, S | 1 |
Kroese, ED; Meerman, JH; Mohn, GR; Zeilmaker, MJ | 1 |
Castegnaro, M; De Méo, M; Duménil, G; Laget, M | 1 |
Fogel, S; Maloney, DH; Moser, SF; Piegorsch, WW; Resnick, MA; Whittaker, SG | 1 |
Bridges, BA; Cole, J; Diot, MC; Richmond, FN | 1 |
Karwan, A; Klein, F; Wintersberger, U | 2 |
Pattee, PA; Tam, JE | 1 |
Domshlak, MG; Sanotskiĭ, IV; Serebrianyĭ, AM | 1 |
Faustman, EM; Gage, D; Kirby, Z; Varnum, M | 1 |
Babudri, N; Politi, MG | 1 |
Granath, F; Kolman, A; Näslund, M | 1 |
Pueyo, C; Roldán-Arjona, T; Ruiz-Rubio, M | 1 |
Piperakis, SM | 1 |
Alonso, JC; Lüder, G; Tailor, RH | 1 |
Boehnke, M; Chin, B; Tarlo, KS | 1 |
Domon, OE; Kodell, RL; McGarrity, LJ; Morris, SM; Stegall, DR | 1 |
Babudri, N; Morpurgo, G | 1 |
Boullier, BA; McKenna, PG | 1 |
Karwan, A; Wintersberger, U | 1 |
Matsuda, Y; Tobari, I | 1 |
Herrera, RJ; Luckett, DC; Mukherjee, AB | 1 |
Dodson, LA; Masker, WE | 1 |
Stratford, IJ; Walling, JM | 1 |
Frosina, G; Laval, F | 1 |
Christensen, RB; Lawrence, CW; Nisson, PE | 1 |
Bruce, RJ; Gollapudi, BB; Sinha, AK | 1 |
Butterworth, BE; Doolittle, DJ; Furlong, JW | 1 |
Gupta, RS; Siminovitch, L; Srinivasan, PR | 1 |
Barnes, MC; Sonnenfeld, G; Streips, UN | 1 |
Jeggo, PA; Kemp, LM | 1 |
Behlau, I; Shanabruch, WG; Walker, GC | 1 |
Behlau, I; Rein, RP; Shanabruch, WG; Walker, GC | 1 |
Baumen, CF; Dusenbery, RL; Smith, PD | 1 |
Anjaria, KB; Madhvanath, U | 1 |
Dusenbery, RL; McCormick, SC; Smith, PD | 1 |
Balganesh, M; Setlow, JK | 1 |
Schrotel, KR; Skare, JA | 1 |
Campbell, LA; Yasbin, RE | 1 |
Mahna, SK | 1 |
Sakaguchi, K; Sono, A | 1 |
Kikuchi, Y; Yamamoto, KI | 1 |
Natarajan, AT; Simons, JW; van Zeeland, AA; Vogel, EW | 1 |
Dornish, JM; Markussen, G; Smith-Kielland, I | 1 |
Kaina, B | 1 |
Evans, HH; Glazier, KG; Horng, MF; Weber, MC | 1 |
Ahmed, FE | 1 |
Aslanian, MM; Kim, AI | 2 |
Barfknecht, TR; Little, JB | 3 |
Hicks, RM; Severs, NJ; Tudor, RJ | 1 |
Brookman, KW; Carrano, AV; Dillehay, LE; Mazrimas, JA; Minkler, JL; Mooney, CL; Thompson, LH | 1 |
Moseley, BE; Tempest, PR | 1 |
Olaiya, AF; Sogin, SJ; Steed, JR | 1 |
Defais, M; Schendel, PF | 1 |
de Moraes, EC; Tyrrell, RM | 1 |
Sklar, R; Strauss, B | 1 |
Hannan, MA; Nasim, A; Nestmann, ER | 1 |
Brouwer, J; Glickman, BW; Todd, PA | 1 |
Davnichenko, LS; Rapoport, IA; Vasil'eva, SV | 1 |
Hieda-Shiomi, N; Sato, K; Shiomi, T | 1 |
Duncan, AM; Evans, HJ | 1 |
Meuth, M | 1 |
De Brij, RJ; Den Engelse, L; Floot, BG; Scherer, E | 1 |
Heiderstädt, R; Mendel, J; Schreiber, D | 1 |
Jenssen, D; Ramel, C | 1 |
Peterson, AR | 1 |
Comendador, MA; Ferreiro, JA; Sierra, LM | 1 |
Aboul-Ela, N; Jacobson, MK; Stamato, TD; Witmer, MV | 1 |
Bronzetti, G; Fiorio, R | 1 |
Hayashi, M; Honma, M; Matsuoka, A; Sofuni, T; Suzuki, T; Zhang, LS | 1 |
Faustman, EM; Seeley, MR | 3 |
Habraken, Y; Laval, F | 1 |
Creus, A; Marcos, R; Soriano, S; Xamena, N | 1 |
Hoff, E; Klungland, A; Laake, K; Seeberg, E | 1 |
Savel'eva, GE; Zhestianikov, VD | 1 |
Bronzetti, G; Fiorio, R; Vellosi, R | 1 |
Abril, N; Alejandre, E; Hera, C; Margison, GP; Pueyo, C; Rafferty, JA | 1 |
Hamilton, JW; McCaffrey, J | 1 |
Dragonetti, E; Giordano, V; Mallardo, M; Quinto, I; Scala, G | 1 |
Bjørås, M; Hoff, E; Klungland, A; Seeberg, E | 1 |
Baldassarre, F; Dragonetti, E; Mallardo, M; Quinto, I; Ruocco, MR; Scala, G | 1 |
Bronzetti, G; Della Croce, C; Macri, E; Morichetti, E; Salvadori, C | 1 |
Clair, JH; DeLuca, JG; Dolbeare, F; Hyland, RJ; Kleemeyer, KM; Miller, JE; Nichols, WW; Selden, JR | 1 |
Hughes, PE; Mori, N; Okazaki, T; Schneider, EL; Yoshida, T | 1 |
Koppen, G; Verschaeve, L | 1 |
Korolev, VG; Koval'tsova, SV | 1 |
Pandrangi, R; Petras, M; Ralph, S; Vrzoc, M | 1 |
Cunningham, JM; Delaney, CA; Di Matteo, M; Dunger, A; Green, IC; Green, MH | 1 |
Cabré, O; Creus, A; Marcos, R; Suárez, S; Velázquez, A; Xamena, N | 1 |
Ehrlich, BE; Quinn, KE | 1 |
Baan, RA; Bergmans, A; van Delft, JH | 1 |
Brooks, T; Carr, GJ; Douglas, GR; Gorelick, NJ; Liegibel, UM; Lockhart, AC; Margolin, BH; Piegorsch, WW; Suzuki, T; Thybaud, V; van Delft, JH | 1 |
Hayashi, M; Honma, M; Sofuni, T | 1 |
Huang, W; Smith, PD | 1 |
Bärtsch, S; Sengstag, C; Würgler, FE | 1 |
Cabré, O; Marcos, R; Soriano, S; Velázquez, A; Xamena, N | 1 |
Chethan, GK; Guruprasad, KP; Harish, SK; Mahmood, R; Manjunath, KR; Vasudev, V | 1 |
Gichner, T; Plewa, MJ; Ptácek, O; Stavreva, DA | 1 |
Galli, A; Schiestl, RH | 1 |
Henderson, DS | 1 |
Han, HM; Jung, KK; Kang, SY; Kim, SH; Kim, TG; Lee, YK; Oh, HY; Rheu, HM | 1 |
Creus, A; Kaya, B; Marcos, R; Velázquez, A; Yanikoğlu, A | 1 |
Biber, J; Forster, IC; Lambert, G; Murer, H | 1 |
Howlett, NG; Schiestl, RH | 1 |
Hill, SA | 1 |
Elsner, M; Guldbakke, B; Lenzen, S; Munday, R; Tiedge, M | 1 |
Harbach, PR; Swenson, DH; Trzos, RJ | 1 |
Loussouarn, G; Masia, R; Nichols, CG; Phillips, LR; Rose, T | 1 |
Bilbao, C; Comendador, MA; Ferreiro, JA; Sierra, LM | 1 |
González-Beltrán, F; Morales-Ramírez, P | 1 |
Li, W | 1 |
Shuai, PQ; Wang, YJ; Zhang, LS | 1 |
Devaux, A; Ferrier, V; Gauthier, L; Mailhes, C; Mouchet, F | 1 |
Alekseev, SY; Evstukhina, TA; Fedorova, IV; Gracheva, LM; Kelberg, EP; Korolev, VG; Kovaltsova, SV | 1 |
Chowdhuri, DK; Dhawan, A; Saxena, DK; Siddique, HR | 1 |
Dhawan, A; Shanker, R; Vajpayee, P | 1 |
Doak, SH; Jenkins, GJ; Johnson, GE; Parry, EM; Parry, JM; Quick, E | 1 |
Bhattacharyya, J; Enkvetchakul, D; Jeliazkova, I; Nichols, CG | 1 |
Chan, CL; Jauert, PA; Kirkpatrick, DT; Legrand, M | 1 |
Güerci, A; Liviac, D; Marcos, R | 1 |
Prasad, AV; Ramakrishna, K; Raman, NV; Rao, KM; Reddy, KS | 1 |
Gocke, E; Müller, L; Pfister, T | 1 |
Donovan, P; Smith, G | 1 |
Camadro, EL; Lukaszewicz, G; Menone, ML; Pérez, DJ | 1 |
Chandrashekhar, TG; Ganguly, S; Kakadiya, PR; Reddy, BP; Singh, DK; Singh, V | 1 |
Gopinath, PM; Guruprasad, KP; Satyamoorthy, K; Sewram, V; Sharma, RS; Singh, VJ; Subramanian, A; Varier, PM | 1 |
Kuehner, S; Linsenmeyer, R; Schütz, P; Speit, G | 1 |
Holzmann, K; Kuehner, S; Speit, G | 1 |
Honma, M; Kimura, A; Miyata, A | 1 |
Guérard, M; Tang, L; Zeller, A | 1 |
Abraham, L; Bodger, OG; Dearfield, KL; Gollapudi, BB; Heflich, RH; Hixon, JG; Johnson, GE; Lovell, DP; MacGregor, JT; Pottenger, LH; Soeteman-Hernández, LG; Tanir, JY; Thompson, CM; Thybaud, V; van Benthem, J; White, PA; Zeiger, E | 1 |
Aardema, MJ; Bruce, S; Hewitt, N; Lawlor, T; Pant, K; Springer, S | 1 |
Guérard, M; Plappert-Helbig, U | 1 |
Chang, C; Huang, L; Wu, Z; Yang, Z; Zhang, C | 1 |
Liu, W; Xu, J; Zheng, F; Zheng, X; Zhou, J | 1 |
Cruces, MP; Pimentel, E | 1 |
2 review(s) available for ethyl methanesulfonate and methyl methanesulfonate
Article | Year |
---|---|
Macromolecular complexes produced by chemical carcinogens and ultraviolet radiation.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Albumins; Alkylating Agents; Carcinogens; Centrifugation, Isopycnic; Chemical Phenomena; Chemistry; Chromatography, Gel; DNA; Ethyl Methanesulfonate; Hydroxyacetylaminofluorene; In Vitro Techniques; Mechlorethamine; Methyl Methanesulfonate; Muramidase; Proteins; RNA; Ultraviolet Rays | 1977 |
Influence of mus201 and mus308 mutations of Drosophila melanogaster on the genotoxicity of model chemicals in somatic cells in vivo measured with the comet assay.
Topics: Animals; Comet Assay; DNA Damage; DNA Polymerase I; DNA Repair; DNA Repair Enzymes; DNA-Binding Proteins; DNA-Directed DNA Polymerase; Drosophila melanogaster; Drosophila Proteins; Endonucleases; Ethyl Methanesulfonate; Ethylnitrosourea; Hydrogen-Ion Concentration; Methyl Methanesulfonate; Mutagens; Nuclear Proteins; Transcription Factors | 2002 |
189 other study(ies) available for ethyl methanesulfonate and methyl methanesulfonate
Article | Year |
---|---|
Survival and liquid holding recovery in UV-sensitive strains of Saccharomyces cerevisiae after treatment with chemical mutagens and radiation.
Topics: Alkylating Agents; Butanes; Epoxy Compounds; Ethyl Methanesulfonate; Methyl Methanesulfonate; Mutagens; Mutation; Nitrous Acid; Saccharomyces cerevisiae; Ultraviolet Rays; X-Rays | 1976 |
Effects of various chemical agents on sister chromatid exchanges, chromosome aberrations, and DNA repair in normal and abnormal human lymphoid cell lines.
Topics: 4-Nitroquinoline-1-oxide; Animals; Cell Line; Cell Survival; Chromosome Aberrations; Crossing Over, Genetic; DNA Repair; Ethyl Methanesulfonate; Humans; Leukemia, Experimental; Lymphocytes; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mitomycins | 1979 |
Genetic control of mutagen sensitivity in Drosophila melanogaster: a new allele at the mei-9 locus on the X-chromosome.
Topics: Alleles; Animals; Chromosome Mapping; Crosses, Genetic; Drosophila melanogaster; Ethyl Methanesulfonate; Female; Genotype; Male; Methyl Methanesulfonate; Mutagens; Mutation; Sex Chromosomes; X Chromosome | 1979 |
Evidence that induction and suppression of mutations and recombinations by chemical mutagens in S. cerevisiae during mitosis are jointly correlated.
Topics: 4-Nitroquinoline-1-oxide; Acridine Orange; Chlorophenols; Dinitrofluorobenzene; Drug Interactions; Ethyl Methanesulfonate; Halogenated Diphenyl Ethers; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mitosis; Mutagens; Mutation; Phenyl Ethers; Recombination, Genetic; Saccharomyces cerevisiae; Sodium Nitrite; Triethylenemelamine | 1979 |
Further characterization of a cell-free system for measuring replicative and repair DNA synthesis with cultured human fibroblasts and evidence for the involvement of DNA polymerase alpha in DNA repair.
Topics: 4-Nitroquinoline-1-oxide; Acetoxyacetylaminofluorene; Cell Line; Cell-Free System; DNA Polymerase II; DNA Repair; DNA Replication; DNA-Directed DNA Polymerase; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Ethyl Methanesulfonate; Fibroblasts; Humans; Methyl Methanesulfonate; Ultraviolet Rays | 1979 |
Forward mutation assays using bacteria and 8-azaguanine.
Topics: Acridines; Azaguanine; Culture Media; Drug Resistance, Microbial; Ethyl Methanesulfonate; Fluorenes; Histidine; Hycanthone; Methyl Methanesulfonate; Mutagens; Nitrosoguanidines; Propiolactone; Salmonella typhimurium; Streptozocin | 1978 |
Difference in the action of ethyl and methyl methane sulfonates on DNA template activity for RNA synthesis in vitro.
Topics: DNA, Viral; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Ethyl Methanesulfonate; Kinetics; Mesylates; Methyl Methanesulfonate; Molecular Weight; Ribosomes; RNA, Bacterial; RNA, Viral; Templates, Genetic; Time Factors; Transcription, Genetic | 1975 |
A mammalian spot test: induction of genetic alterations in pigment cells of mouse embryos with x-rays and chemical mutagens.
Topics: Animals; Chromosome Aberrations; Ethyl Methanesulfonate; Female; Genes, Recessive; Male; Maternal-Fetal Exchange; Mesylates; Methyl Methanesulfonate; Mice; Mutation; Pigmentation; Pregnancy; Radiation Genetics; Recombination, Genetic; Time Factors | 1975 |
An assay for phosphotriester formation in the reaction of alkylating agents with deoxyribosenucleic acid in vitro and in vivo.
Topics: Animals; Coliphages; DNA, Viral; Ethyl Methanesulfonate; Ethylnitrosourea; Liver; Mathematics; Mesylates; Methyl Methanesulfonate; Methylnitrosourea; Mice; Molecular Weight; Nitrosourea Compounds; Sulfuric Acids | 1976 |
Inactivation of the T7 coliphage by monofunctional alkylating agents. Action of phage adsorption and injection of its DNA.
Topics: Binding Sites; Biological Transport; Coliphages; DNA Replication; DNA, Viral; Escherichia coli; Ethyl Methanesulfonate; Mesylates; Methyl Methanesulfonate; Virus Replication | 1976 |
Studies on DNA repair in early spermatid stages of male mice after in vivo treatment with methyl-, ethyl-, propyl-, and isopropyl methanesulfonate.
Topics: 1-Propanol; Animals; DNA Repair; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Male; Mesylates; Methyl Methanesulfonate; Mice; Spermatids; Spermatozoa; Testis; Thymidine; Tritium | 1976 |
Action of ethyl and methyl methane sulfonates on DNA injection and genetic recombination in T7 bacteriophage.
Topics: Alkylation; Coliphages; DNA, Viral; Ethyl Methanesulfonate; Mesylates; Methyl Methanesulfonate; Mutation; Recombination, Genetic | 1976 |
Dominant lethal studies with alkylating agents: dose-response relationships.
Topics: Alkylating Agents; Animals; Ethyl Methanesulfonate; Female; Genes, Dominant; Genes, Lethal; Male; Mesylates; Methyl Methanesulfonate; Mutagens; Pregnancy; Reproduction; Time Factors | 1976 |
Cytological effects of three alkylating agents in Drosophila.
Topics: Alkylating Agents; Animals; Chromosome Aberrations; Chromosome Inversion; Chromosomes; Drosophila melanogaster; Ethyl Methanesulfonate; Mesylates; Methyl Methanesulfonate | 1976 |
Methyl methanesulphonate mutagenesis in L5178Y mouse lymphoma cells.
Topics: Cell Line; Dose-Response Relationship, Drug; Drug Resistance; Ethyl Methanesulfonate; Lymphoma; Mesylates; Methyl Methanesulfonate; Mutagens; Mutation; Neoplasms, Experimental; Ouabain; Thioguanine; Thymidine | 1978 |
Alkyl methane sulfonate mutation of diploid human lymphoblasts and Salmonella typhimurium.
Topics: Animals; Cell Line; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Humans; Lymphocytes; Mammals; Mesylates; Methyl Methanesulfonate; Mutation; Salmonella typhimurium; Species Specificity | 1978 |
Comparative mutagenicity of alkylsulfate and alkanesulfonate derivatives in Chinese hamster ovary cells.
Topics: Cell Line; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Hypoxanthine Phosphoribosyltransferase; Mesylates; Methyl Methanesulfonate; Mutagens; Mutation; Sulfuric Acids | 1978 |
[Postnatal and transplacental carcinogenic effects of methyl methanesulphonate (MMS) and ethyl methanesulphonate (EMS) in hooded rats (author's transl)].
Topics: Age Factors; Animals; Animals, Newborn; Ethyl Methanesulfonate; Female; Mesylates; Methyl Methanesulfonate; Neoplasms, Experimental; Neuroma; Pregnancy; Pregnancy, Animal; Rats | 1978 |
Evidence that UV-inducible error-prone repair is absent in Haemophilus influenzae Rd, with a discussion of the relation to error-prone repair of alkylating-agent damage.
Topics: Alkylating Agents; DNA Repair; Ethyl Methanesulfonate; Haemophilus influenzae; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mutagens; Mutation; Nitrogen Mustard Compounds; Nitroso Compounds; Phenotype; Ultraviolet Rays; X-Rays | 1977 |
Mutagenesis of yeast by hydrazine: dependence upon post-treatment cell division.
Topics: Canavanine; Cell Division; Drug Resistance, Microbial; Ethyl Methanesulfonate; Genes; Hydrazines; Hydroxylamines; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mutagens; Mutation; Nitrous Acid; Saccharomyces cerevisiae; Ultraviolet Rays | 1977 |
Escherichia coli gene that controls sensitivity to alkylating agents.
Topics: Alkylating Agents; Conjugation, Genetic; Drug Resistance, Microbial; Escherichia coli; Ethyl Methanesulfonate; Genes; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mitomycins; Mutation; Transduction, Genetic | 1978 |
Pathways of mutagenesis and repair in Escherichia coli exposed to low levels of simple alkylating agents.
Topics: Alkylating Agents; DNA Repair; DNA, Bacterial; Escherichia coli; Ethyl Methanesulfonate; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mutation | 1978 |
In vitro breakage of plasmid DNA by mutagens and pesticides.
Topics: Aldrin; Chlordan; DDT; Dichlorvos; Dieldrin; DNA, Circular; Escherichia coli; Ethyl Methanesulfonate; Heptachlor; Malathion; Methyl Methanesulfonate; Methyl Parathion; Methylnitronitrosoguanidine; Mutagens; Pesticides; Plasmids; Toxaphene | 1978 |
Cross sensitivity of mutator strains to physical and chemical mutagens.
Topics: DNA Repair; Ethyl Methanesulfonate; Gamma Rays; Genes; Methyl Methanesulfonate; Mutation; Saccharomyces cerevisiae; Ultraviolet Rays | 1979 |
The mutability of the minute loci and sex-linked recessive lethals in Drosophila melanogaster.
Topics: Animals; Crosses, Genetic; Drosophila melanogaster; Ethyl Methanesulfonate; Female; Gene Frequency; Genes, Lethal; Genes, Recessive; Genetic Linkage; Male; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Nitrosomethylurethane; Sex Chromosomes | 1977 |
Cytotoxicity and mutagenicity of alkylating agents in cultured mammalian cells (CHO/HGPRT system): mutagen treatment in the presence or absence of serum.
Topics: Alkylating Agents; Animals; Cell Line; Cell Survival; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Female; Hypoxanthine Phosphoribosyltransferase; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mutagens; Mutation; Nitrosourea Compounds; Ovary | 1979 |
The induction of sister-chromatid exchanges in cultured fish cells (Ameca splendens) by carcinogenic mutagens.
Topics: Animals; Bromodeoxyuridine; Carcinogens; Cell Line; Cricetinae; Crossing Over, Genetic; Ethyl Methanesulfonate; Fibroblasts; Fishes; Humans; Karyotyping; Lymphocytes; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mutation; Sister Chromatid Exchange | 1979 |
Unscheduled DNA synthesis in spermatogenic cells of mice treated in vivo with the indirect alkylating agents cyclophosphamide and mitomen.
Topics: Animals; Chromosome Aberrations; Chromosomes; Cyclophosphamide; DNA Repair; Ethyl Methanesulfonate; Male; Mechlorethamine; Methyl Methanesulfonate; Mice; Mutagens; Mutation; Spermatozoa; Time Factors | 1978 |
Sensitivity to five mutagens in Fanconi's anemia as measured by the micronucleus method.
Topics: Anemia, Aplastic; Bromodeoxyuridine; Cell Nucleus; Child; Child, Preschool; Chromosome Aberrations; Ethyl Methanesulfonate; Fanconi Anemia; Female; Heterozygote; Humans; In Vitro Techniques; Lymphocytes; Male; Methods; Methyl Methanesulfonate; Mitomycins; Mutagens; Radiation Tolerance | 1978 |
Detection of alkylating agents by the analysis of amino acid residues in hemoglobin and urine. 1. The in vivo and in vitro effects of ethyl methanesulfonate, methyl methanesulfonate, hycanthone methanesulfonate, and naltrexone.
Topics: Alkylating Agents; Amino Acid Sequence; Amino Acids; Animals; Ethyl Methanesulfonate; Hemoglobins; Histidine; Humans; Hycanthone; Male; Methyl Methanesulfonate; Naltrexone; Phenylalanine; Proline; Rats | 1978 |
Oncogenesis, mutagenesis, DNA damage, and cytotoxicity in cultured mammalian cells treated with alkylating agents.
Topics: Alkylating Agents; Cell Line; Cell Survival; Cell Transformation, Neoplastic; DNA Repair; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mutagens | 1979 |
Transversion mutagenesis in bacteriophage T4.
Topics: Base Sequence; Cations, Divalent; Coliphages; DNA, Viral; Escherichia coli; Ethyl Methanesulfonate; Magnesium; Methyl Methanesulfonate; Mutation; Phenotype; Temperature; Thymine | 1975 |
Sister chromatid exchange as an assay for genetic damage induced by mutagen-carcinogens. I. In vivo test for compounds requiring metabolic activation.
Topics: Animals; Biotransformation; Carcinogens; Cells, Cultured; Chromosomes; Crossing Over, Genetic; Cyclophosphamide; Ethyl Methanesulfonate; Genetic Techniques; Lymphocytes; Male; Methyl Methanesulfonate; Mutagens; Rabbits | 1976 |
Sister chromatid exchange as an assay for genetic damage induced by mutagen-carcinogens. II. In vitro test for compounds requiring metabolic activation.
Topics: Animals; Biotransformation; Carcinogens; Cells, Cultured; Chromosomes; Crossing Over, Genetic; Cyclophosphamide; Ethyl Methanesulfonate; Genetic Techniques; In Vitro Techniques; Lymphocytes; Male; Methyl Methanesulfonate; Mutagens; Rabbits | 1976 |
The fluctuation test as a more sensitive system for determining induced mutation in L5178Y mouse lymphoma cells.
Topics: Cells, Cultured; Dose-Response Relationship, Drug; Drug Resistance; Ethyl Methanesulfonate; Genetic Techniques; Lymphoma; Methyl Methanesulfonate; Mutation; Neoplasms, Experimental; Ouabain | 1976 |
Increased DNA polymerase and ATP-dependent deoxyribonuclease activities following DNA damages in mycobacterium smegmatis.
Topics: Acridines; Adenosine Triphosphate; Bacterial Proteins; Caffeine; Deoxyribonucleases; DNA-Directed DNA Polymerase; DNA, Bacterial; Ethidium; Ethyl Methanesulfonate; Fluorouracil; Mechlorethamine; Methyl Methanesulfonate; Mitomycins; Mutation; Mycobacterium; Nalidixic Acid; Proflavine; Ultraviolet Rays | 1977 |
Prophage inductive efficiency of alkylating agents and radiations.
Topics: Alkylating Agents; Coliphages; Ethyl Methanesulfonate; Ethylene Oxide; Gamma Rays; Lysogeny; Mechlorethamine; Methyl Methanesulfonate; Neutrons; Radiation Effects; Sulfuric Acid Esters; Virus Replication | 1975 |
Factors affecting the quantitation of dose-response curves for mutation induction in V79 Chinese hamster cells after exposure to chemical and physical mutagens.
Topics: Cell Division; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Ethyl Methanesulfonate; Methyl Methanesulfonate; Mutagens; Mutation; Radiation Genetics; Ultraviolet Rays; X-Rays | 1975 |
Proceedings: The use of yeast genetic systems in environmental mutagenesis.
Topics: Environmental Pollutants; Ethyl Methanesulfonate; Methods; Methyl Methanesulfonate; Mutagens; Saccharomyces | 1975 |
A comparison of the 8-azaguanine and ouabain-resistance systems for the selection of induced mutant Chinese hamster cells.
Topics: Animals; Azaguanine; Captan; Cell Line; Cricetinae; Drug Resistance; Ethyl Methanesulfonate; Gamma Rays; Methyl Methanesulfonate; Mutation; Ouabain; Potassium; Radiation Genetics; Ultraviolet Rays | 1975 |
Combined mutagenicity of methyl methanesulfonate and ethyl methanesulfonate in Chinese hamster V79 cells.
Topics: Animals; Cells, Cultured; Chromosome Aberrations; Cricetinae; Cricetulus; Drug Synergism; Ethyl Methanesulfonate; Methyl Methanesulfonate; Mutagens | 1992 |
Base alterations in yeast induced by alkylating agents with differing Swain-Scott substrate constants.
Topics: Alkylating Agents; Base Sequence; DNA Mutational Analysis; DNA, Fungal; Ethyl Methanesulfonate; Ethylnitrosourea; Gene Amplification; Methyl Methanesulfonate; Methylnitrosourea; Mutagens; Saccharomyces cerevisiae | 1992 |
Comparison of mutagenicity results for nine compounds evaluated at the hgprt locus in the standard and suspension CHO assays.
Topics: Acrylates; Aminoacridines; Animals; Cell Line; Chromosome Aberrations; Cricetinae; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Female; Hypoxanthine Phosphoribosyltransferase; Lymphoma; Methyl Methanesulfonate; Mice; Mutagenicity Tests; Mutagens; Mutation; Nitrogen Mustard Compounds | 1991 |
Inhibition of O6-alkylguanine-DNA alkyltransferase and DNase I activities in vitro by some alkylating substances and antineoplastic agents.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Bisbenzimidazole; Bleomycin; Brain; Chick Embryo; Deoxyribonucleases; DNA Repair; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Doxorubicin; Ethidium; Ethyl Methanesulfonate; Ethylnitrosourea; Hot Temperature; In Vitro Techniques; Liver; Methyl Methanesulfonate; Methylnitrosourea; Methyltransferases; Novobiocin; O(6)-Methylguanine-DNA Methyltransferase; Substrate Specificity; Suramin; X-Rays | 1991 |
Chemical mutagenesis and DNA synthesis in cdc8, a DNA replication mutant of Saccharomyces cerevisiae.
Topics: DNA Replication; DNA, Fungal; Epoxy Compounds; Ethyl Methanesulfonate; Methyl Methanesulfonate; Mutagenesis; Mutagens; Saccharomyces cerevisiae; Thymidine Kinase | 1991 |
Flow cytometric evaluation of cell-cycle progression in ethyl methanesulfonate and methyl methanesulfonate-exposed P3 cells: relationship to the induction of sister-chromatid exchanges and cellular toxicity.
Topics: Cell Cycle; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Flow Cytometry; Humans; In Vitro Techniques; Methyl Methanesulfonate; Sister Chromatid Exchange; Teratoma; Time Factors; Tumor Cells, Cultured | 1991 |
Alkylating agent hypersensitivity in poly(adenosine diphosphate-ribose) polymerase deficient cell lines.
Topics: 4-Nitroquinoline-1-oxide; Alkylating Agents; Animals; Cell Line; Cell Survival; Cricetinae; DNA Repair; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Ethylnitrosourea; Lethal Dose 50; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Poly(ADP-ribose) Polymerases; Sulfuric Acid Esters | 1991 |
Nucleotide pools and mutagenic effects of alkylating agents in wild-type and APRT-deficient Friend erythroleukaemia cells.
Topics: Alkylating Agents; Animals; Cell Line; Deoxyribonucleotides; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Friend murine leukemia virus; In Vitro Techniques; Leukemia, Erythroblastic, Acute; Methyl Methanesulfonate; Methyltransferases; Mice; Mutagenesis; Nucleotides; Ribonucleosides | 1991 |
Responses of the L5178Y mouse lymphoma forward mutation assay: V. Gases and vapors.
Topics: Air Pollutants; Alkenes; Animals; Butadienes; Dichloroethylenes; Epoxy Compounds; Ethyl Methanesulfonate; Lymphoma; Methyl Methanesulfonate; Methylcholanthrene; Mice; Mutagenicity Tests; Mutagens; Thymidine Kinase; Tumor Cells, Cultured | 1991 |
Reevaluation of the 9 compounds reported conclusive positive in yeast Saccharomyces cerevisiae aneuploidy test systems by the Gene-Tox Program using strain D61.M of Saccharomyces cerevisiae.
Topics: Acetone; Aneuploidy; Benomyl; Benzimidazoles; Biotransformation; Carbamates; Chromosomes, Fungal; Cyclophosphamide; Ethyl Methanesulfonate; Evaluation Studies as Topic; Methyl Methanesulfonate; Mitosis; Mutagenicity Tests; Mutagens; Mutation; Nocodazole; p-Fluorophenylalanine; Saccharomyces cerevisiae; Tetradecanoylphorbol Acetate | 1991 |
Preventive action of thioethers towards in vitro DNA binding and mutagenesis in E. coli K12 by alkylating agents.
Topics: Alkylating Agents; Benzoates; DNA; Escherichia coli; Ethyl Methanesulfonate; Ethylnitrosourea; Methyl Methanesulfonate; Methylnitrosourea; Mutagenicity Tests; Sulfides | 1990 |
Evaluation of methods for destruction of some alkylating agents.
Topics: Alkylating Agents; Drug Residues; Ethyl Methanesulfonate; Evaluation Studies as Topic; Hazardous Waste; Humans; Indicators and Reagents; Methyl Methanesulfonate; Mutagenicity Tests; Mutagens; Refuse Disposal; Salmonella; Sulfuric Acid Esters | 1990 |
The detection of mitotic and meiotic chromosome gain in the yeast Saccharomyces cerevisiae: effects of methyl benzimidazol-2-yl carbamate, methyl methanesulfonate, ethyl methanesulfonate, dimethyl sulfoxide, propionitrile and cyclophosphamide monohydrate.
Topics: Aneuploidy; Benzimidazoles; Carbamates; Chromosomes, Fungal; Cyclophosphamide; Dimethyl Sulfoxide; Ethyl Methanesulfonate; Meiosis; Methyl Methanesulfonate; Mitosis; Mutagens; Nitriles; Saccharomyces cerevisiae; Temperature | 1990 |
Comparative induction of gene mutations and chromosome damage by 1-methoxy-1,3,5-cycloheptatriene (MCHT), 2. Results using L5178Y mouse lymphoma cells to detect both gene and chromosome damage; validation with ionizing radiation, methyl methanesulphonate,
Topics: Animals; Benzo(a)pyrene; Chromosome Aberrations; Chromosomes; Cloning, Molecular; Cycloheptanes; DNA Damage; Ethyl Methanesulfonate; Genes; Lymphoma; Methyl Methanesulfonate; Mice; Micronucleus Tests; Mutagens; Mutation; Tumor Cells, Cultured | 1990 |
Pedigree analyses of yeast cells recovering from DNA damage allow assignment of lethal events to individual post-treatment generations.
Topics: DNA Damage; Ethyl Methanesulfonate; Genes, Fungal; Genes, Lethal; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mutagens; Mutation; Nitrous Acid; Probability; Saccharomyces cerevisiae | 1990 |
Characterization and genetic mapping of a mutation affecting apurinic endonuclease activity in Staphylococcus aureus.
Topics: 4-Nitroquinoline-1-oxide; Chromosome Mapping; Chromosomes, Bacterial; Deoxyribonuclease IV (Phage T4-Induced); DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; Endodeoxyribonucleases; Ethyl Methanesulfonate; Genes, Bacterial; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Mutation; Nitrous Acid; Recombination, Genetic; Staphylococcus aureus; Ultraviolet Rays | 1986 |
[Study of the possibilities of using a short-term test system in vitro for detection of potential mutagens (carcinogens)].
Topics: Animals; Aziridines; Carcinogenicity Tests; Carcinogens; Cattle; DNA; Ethyl Methanesulfonate; Luminescent Measurements; Methyl Methanesulfonate; Methylnitrosourea; Mutagenicity Tests; Mutagens; Thiotepa; Time Factors | 1989 |
In vitro developmental toxicity of five direct-acting alkylating agents in rodent embryos: structure-activity patterns.
Topics: Alkylating Agents; Analysis of Variance; Animals; Brain; Dose-Response Relationship, Drug; Embryo, Mammalian; Ethyl Methanesulfonate; Ethylnitrosourea; Female; In Vitro Techniques; Maternal-Fetal Exchange; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Methylnitrosourea; Pregnancy; Rats; Rats, Inbred Strains | 1989 |
After a single treatment with EMS the number of non-colony-forming cells increases for many generations in yeast populations.
Topics: Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Methyl Methanesulfonate; Saccharomyces cerevisiae; Time Factors; X-Rays | 1989 |
Different action of MMS and EMS in UV-sensitive strains of Aspergillus nidulans.
Topics: Alkylation; Aspergillus nidulans; DNA Repair; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Methyl Methanesulfonate; Mutation; Ultraviolet Rays | 1989 |
Modifying action of gamma-radiation in mutagenesis of E. coli WU36-10 induced by ethylene oxide, ethyl methanesulfonate and methyl methanesulfonate.
Topics: DNA Repair; Escherichia coli; Ethyl Methanesulfonate; Ethylene Oxide; Gamma Rays; Methyl Methanesulfonate; Mutation; Statistics as Topic | 1989 |
Simple method for precise determination of chemical lethality in the L-arabinose resistance test of Salmonella typhimurium.
Topics: 2-Naphthylamine; Arabinose; Biotransformation; Drug Resistance, Microbial; Ethyl Methanesulfonate; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mutagenicity Tests; Mutagens; Salmonella typhimurium | 1989 |
Enhanced reactivation of UV-irradiated adenovirus 2 is not associated with enhanced mutagenesis in carcinogen-pretreated HeLa cells.
Topics: Adenoviruses, Human; Aflatoxin B1; Aflatoxins; DNA Repair; Ethyl Methanesulfonate; HeLa Cells; Humans; Methyl Methanesulfonate; Mutation; Ultraviolet Rays; Virus Replication | 1987 |
Characterization of recombination-deficient mutants of Bacillus subtilis.
Topics: Bacillus subtilis; Bacterial Proteins; DNA Damage; DNA Repair; DNA, Bacterial; Ethyl Methanesulfonate; Methyl Methanesulfonate; Mutation; Recombination, Genetic; SOS Response, Genetics; Transfection; Transformation, Bacterial; Virus Activation | 1988 |
Synergism of mutant frequencies in the mouse lymphoma cell mutagenicity assay by binary mixtures of methyl methanesulfonate and ethyl methanesulfonate.
Topics: Animals; Drug Synergism; Ethyl Methanesulfonate; Lymphoma; Methyl Methanesulfonate; Mice; Mutagenicity Tests; Mutagens; Mutation; Thymidine Kinase | 1988 |
Sister chromatid exchange frequency, cellular replication and relative cloning efficiency in human teratocarcinoma-derived cells.
Topics: Cell Division; Cell Line; Cell Survival; Clone Cells; Ethyl Methanesulfonate; Humans; Methyl Methanesulfonate; Mutagenicity Tests; Sister Chromatid Exchange; Teratoma | 1988 |
An uvsB mutant of Aspergillus nidulans with high variable spontaneous mutation and intergenic mitotic recombination frequencies.
Topics: Aspergillus nidulans; Crossing Over, Genetic; DNA, Fungal; Ethyl Methanesulfonate; Genes, Fungal; Methyl Methanesulfonate; Mitosis; Mutation; Recombination, Genetic; Ultraviolet Rays | 1988 |
Cell killing and mutagenesis by alkylating agents and UV irradiation in wild-type and deoxycytidine-kinase-deficient Friend murine leukaemia cells.
Topics: Animals; Cell Survival; Clone Cells; Cytarabine; Drug Resistance; Ethyl Methanesulfonate; Leukemia, Experimental; Methyl Methanesulfonate; Mice; Mutagenicity Tests; Mutation; Ultraviolet Rays | 1988 |
Retardation of cell cycle progression in yeast cells recovering from DNA damage: a study at the single cell level.
Topics: Cell Cycle; Cell Nucleus; DNA Damage; DNA Repair; Dose-Response Relationship, Radiation; Ethyl Methanesulfonate; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Nitrous Acid; Saccharomyces cerevisiae | 1987 |
Chromosomal analysis in mouse eggs fertilized in vitro with sperm exposed to ultraviolet light (UV) and methyl and ethyl methanesulfonate (MMS and EMS).
Topics: Animals; Caffeine; Cell Cycle; Chromosome Aberrations; Cytarabine; Ethyl Methanesulfonate; Female; Fertilization in Vitro; Male; Methyl Methanesulfonate; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Spermatozoa; Ultraviolet Rays; Zygote | 1988 |
Spontaneous and induced sister-chromatid exchanges in cultured mosquito cells.
Topics: Aedes; Animals; Bromodeoxyuridine; Cell Line; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Ethylnitrosourea; Methyl Methanesulfonate; Methylnitrosourea; Mutagens; Sister Chromatid Exchange; Species Specificity | 1986 |
Survival and mutagenesis of bacteriophage T7 damaged by methyl methanesulfonate and ethyl methanesulfonate.
Topics: Coliphages; DNA Ligases; DNA Repair; Ethyl Methanesulfonate; Methyl Methanesulfonate; Mutation; Ultraviolet Rays | 1986 |
Chemosensitization by monofunctional alkylating agents.
Topics: Animals; Antineoplastic Agents; Cell Line; Cisplatin; Cricetinae; Drug Synergism; Ethyl Methanesulfonate; In Vitro Techniques; Melphalan; Methyl Methanesulfonate; Methylnitronitrosoguanidine | 1986 |
The O6-methylguanine-DNA-methyltransferase activity of rat hepatoma cells is increased after a single exposure to alkylating agents.
Topics: Alkylating Agents; Animals; Cell Line; Ethyl Methanesulfonate; Liver Neoplasms, Experimental; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Rats | 1987 |
UV and chemical mutagenesis in rev7 mutants of yeast.
Topics: Alleles; Diploidy; Ethyl Methanesulfonate; Genes, Fungal; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mutagens; Mutation; Saccharomyces cerevisiae; Ultraviolet Rays | 1985 |
The role of feeding rejection in Drosophila mutation assays.
Topics: Administration, Oral; Animals; Bromodeoxyuridine; Depression, Chemical; Drosophila melanogaster; Drug Interactions; Ethyl Methanesulfonate; Feeding Behavior; Genes, Lethal; Male; Methyl Methanesulfonate; Mutagenicity Tests; Mutagens; Taste | 1985 |
Assessment of chemically induced DNA repair in primary cultures of human bronchial epithelial cells.
Topics: Aged; Autoradiography; Benzo(a)pyrene; Bronchi; Cells, Cultured; Dimethyl Sulfoxide; Dimethylnitrosamine; DNA Repair; Epithelium; Ethyl Methanesulfonate; Female; Formaldehyde; Humans; Male; Methyl Methanesulfonate; Middle Aged; Pyrenes | 1985 |
Studies on temperature-sensitive mutants of Chinese hamster ovary cells affected in DNA synthesis.
Topics: Alkylating Agents; Animals; Cell Division; Cell Line; Cell Survival; Cricetinae; Cricetulus; DNA; DNA Replication; Drug Resistance; Ethyl Methanesulfonate; Female; Genetic Complementation Test; Genetic Linkage; Hybrid Cells; Methyl Methanesulfonate; Mutation; Ouabain; Ovary; Protein Biosynthesis; RNA; Temperature; Thioguanine | 1980 |
Effect of carcinogens and analogs on interferon induction.
Topics: Animals; Carcinogens; Cells, Cultured; Depression, Chemical; Embryo, Mammalian; Ethyl Methanesulfonate; Interferons; Methyl Methanesulfonate; Mice; Newcastle disease virus | 1981 |
X-ray-sensitive mutants of Chinese hamster ovary cell line. Isolation and cross-sensitivity to other DNA-damaging agents.
Topics: Animals; Bleomycin; Cell Line; Cricetinae; Cricetulus; DNA Repair; Ethyl Methanesulfonate; Female; Methods; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mutation; Ovary; Ultraviolet Rays; X-Rays | 1983 |
Spontaneous mutators of salmonella typhimurium LT2 generated by insertion of transposable elements.
Topics: 4-Nitroquinoline-1-oxide; Chromosome Mapping; Chromosomes, Bacterial; DNA Transposable Elements; Ethyl Methanesulfonate; Genes, Bacterial; Methyl Methanesulfonate; Mutation; Salmonella typhimurium; Ultraviolet Rays | 1981 |
Mutagenesis, by methylating and ethylating agents, in mutH, mutL, mutS, and uvrD mutants of Salmonella typhimurium LT2.
Topics: 4-Nitroquinoline-1-oxide; Alkylating Agents; DNA Repair; Ethyl Methanesulfonate; Genes, Bacterial; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Methylnitrosourea; Models, Genetic; Mutagens; Mutation; Recombination, Genetic; Salmonella typhimurium; Ultraviolet Rays | 1983 |
Mutagen sensitivity of Drosophila melanogaster. VI. Evidence from the excision-defective mei-9AT1 mutant for the timing of DNA-repair activity during spermatogenesis.
Topics: Animals; DNA Repair; Drosophila melanogaster; Ethyl Methanesulfonate; Genes, Lethal; Genes, Recessive; Male; Meiosis; Methyl Methanesulfonate; Mutagens; Spermatogenesis; Time Factors | 1983 |
Combined mutagenic action of chemicals and radiation in diploid yeast.
Topics: 4-Nitroquinoline-1-oxide; Ethyl Methanesulfonate; Gamma Rays; Gene Conversion; Methyl Methanesulfonate; Mutation; Radiation, Ionizing; Saccharomyces cerevisiae; Statistics as Topic | 1983 |
Drosophila mutations at the mei-9 and mus(2)201 loci which block excision of thymine dimers also block induction of unscheduled DNA synthesis by methyl methanesulfonate, ethyl methanesulfonate, N-methyl-N-nitrosourea, UV light and X-rays.
Topics: Animals; DNA Replication; Drosophila melanogaster; Embryo, Nonmammalian; Ethyl Methanesulfonate; Methyl Methanesulfonate; Methylnitrosourea; Mutation; Nitrosourea Compounds; Ultraviolet Rays; X-Rays | 1983 |
Prophage induction in Haemophilus influenzae and its relationship to mutation by chemical and physical agents.
Topics: Bacteriophages; Ethyl Methanesulfonate; Haemophilus influenzae; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Mutagens; Mutation; Ultraviolet Rays; Virus Activation | 1984 |
Alkaline elution of rat testicular DNA: detection of DNA strand breaks after in vivo treatment with chemical mutagens.
Topics: Animals; Dimethyl Sulfoxide; DNA, Single-Stranded; Edetic Acid; Ethyl Methanesulfonate; Ethylnitrosourea; Hydrogen-Ion Concentration; Male; Methyl Methanesulfonate; Methylnitrosourea; Mutagens; Phenols; Polyethylene Glycols; Rats; Testis; Time Factors | 1984 |
Mutagenesis of Neisseria gonorrhoeae: absence of error-prone repair.
Topics: DNA Repair; Dose-Response Relationship, Radiation; Ethyl Methanesulfonate; Genotype; Kinetics; Methyl Methanesulfonate; Mutation; Neisseria gonorrhoeae; Phenotype; Ultraviolet Rays | 1984 |
Transfection assay test system: assay of four chemical mutagens.
Topics: Bacillus subtilis; Bacteriophages; DNA, Viral; Ethyl Methanesulfonate; Hydroxylamine; Hydroxylamines; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mutagenicity Tests; Mutagens; Transfection | 1984 |
Inhibition of protein synthesis antagonizes induction of sister-chromatid exchanges by exogenous agents.
Topics: Animals; Bromodeoxyuridine; Cell Line; Chromosome Aberrations; Cricetinae; Cricetulus; Crossing Over, Genetic; Cycloheximide; Ethyl Methanesulfonate; Floxuridine; Hydroxyurea; Methyl Methanesulfonate; Puromycin; Sister Chromatid Exchange | 1981 |
Studies on micronuclei time response and on the effects of multiple treatments of mutagens on induction of micronuclei.
Topics: Animals; Busulfan; Cell Nucleus; Colchicine; Cyclophosphamide; Cytarabine; Ethyl Methanesulfonate; Floxuridine; Male; Methotrexate; Methyl Methanesulfonate; Mice; Mitomycins; Mutagenicity Tests; Mutagens; Time Factors; Triethylenemelamine; Vincristine | 1981 |
Relationship between cell killing, chromosomal aberrations, sister-chromatid exchanges and point mutations induced by monofunctional alkylating agents in Chinese hamster cells. A correlation with different ethylation products in DNA.
Topics: Alkylating Agents; Animals; Cell Survival; Cells, Cultured; Chromosome Aberrations; Cricetinae; Crossing Over, Genetic; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Ethylnitrosourea; Female; Methyl Methanesulfonate; Methylnitrosourea; Mutation; Sister Chromatid Exchange; Sulfuric Acid Esters | 1984 |
Inhibition of protein A24 lyase by nitrosoureas.
Topics: Animals; Carcinoma, Ehrlich Tumor; Carmustine; Cyanates; Ethyl Methanesulfonate; Ethylnitrosourea; Histones; Isocyanates; Lyases; Methyl Methanesulfonate; Methylnitrosourea; Nitrosourea Compounds; Ubiquitins | 1984 |
Cross-resistance studies with V79 Chinese hamster cells adapted to the mutagenic or clastogenic effect of N-methyl-N'-nitro-N-nitrosoguanidine.
Topics: Animals; Cell Line; Cell Survival; Cricetinae; Cricetulus; Drug Resistance; Ethyl Methanesulfonate; Ethylnitrosourea; Lung; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Methylnitrosourea; Mutagens; Thioguanine; Ultraviolet Rays | 1983 |
Isolation and characterization of BHK cells sensitive to ionizing radiation and alkylating agents.
Topics: Alkylating Agents; Animals; Cell Line; Cell Survival; Cricetinae; Dose-Response Relationship, Drug; Drug Tolerance; Ethyl Methanesulfonate; Kidney; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Radiation Tolerance | 1984 |
The combined action of chemical carcinogens on DNA repair in human cells.
Topics: 2-Acetylaminofluorene; 4-Nitroquinoline-1-oxide; Bromodeoxyuridine; Carcinogens; Cells, Cultured; DNA Repair; Ethyl Methanesulfonate; Fibroblasts; Humans; Methyl Methanesulfonate; Photochemistry; Ultraviolet Rays | 1980 |
[Drosophila mutants sensitive to methylmethane sulfonate. I. Their isolation and genetic analysis].
Topics: Animals; Chromosomes; Drosophila melanogaster; Drug Resistance; Ethyl Methanesulfonate; Ethylnitrosourea; Female; Larva; Male; Methyl Methanesulfonate; Mutation | 1981 |
[Drosophila mutants sensitive to methylmethane sulfonate. II. Cross sensitivity to mutagenic factors].
Topics: Animals; Crosses, Genetic; Dose-Response Relationship, Drug; Drosophila melanogaster; Ethyl Methanesulfonate; Female; Genes, Lethal; Larva; Male; Methyl Methanesulfonate; Mitomycins; Mutation; Nitrosoguanidines; Ultraviolet Rays; X-Rays | 1982 |
Abnormal sensitivity of skin fibroblasts from familial polyposis patients to DNA alkylating agents.
Topics: 4-Nitroquinoline-1-oxide; Alkylating Agents; Cell Survival; DNA; Ethyl Methanesulfonate; Fibroblasts; Humans; Intestinal Polyps; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Skin | 1982 |
Hypersensitivity of ataxia telangiectasia skin fibroblasts to DNA alkylating agents.
Topics: 4-Nitroquinoline-1-oxide; Alkylating Agents; Ataxia Telangiectasia; Cell Line; Cell Survival; Ethyl Methanesulfonate; Fibroblasts; Humans; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Reference Values; Skin | 1982 |
Survival of hereditary retinoblastoma human skin fibroblasts after treatment with DNA-damaging chemicals.
Topics: 4-Nitroquinoline-1-oxide; Alkylating Agents; Cell Survival; Cells, Cultured; Ethyl Methanesulfonate; Eye Neoplasms; Fibroblasts; Humans; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Retinoblastoma; Skin | 1982 |
The induction of urothelial hyperplasia by methyl methanesulphonate and ethyl methanesulphonate.
Topics: Animals; Carcinoma, Transitional Cell; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Female; Hyperplasia; Methyl Methanesulfonate; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Time Factors; Urinary Bladder; Urinary Bladder Neoplasms | 1983 |
A CHO-cell strain having hypersensitivity to mutagens, a defect in DNA strand-break repair, and an extraordinary baseline frequency of sister-chromatid exchange.
Topics: Animals; Cell Line; Clone Cells; Cricetinae; Cricetulus; Crossing Over, Genetic; DNA Repair; Ethyl Methanesulfonate; Female; Methyl Methanesulfonate; Mutation; Ovary; Phenotype; Sister Chromatid Exchange | 1982 |
Defective excision repair in a mutant of Micrococcus radiodurans hypermutable by some monofunctional alkylating agents.
Topics: DNA Repair; Drug Resistance, Microbial; Ethyl Methanesulfonate; Genes, Lethal; Hydroxylamines; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Micrococcus; Mitomycins; Mutagens; Mutation; Nitrous Acid | 1980 |
Deoxyribonucleic acid-deficient strains of Candida albicans.
Topics: Candida albicans; DNA, Fungal; Ethyl Methanesulfonate; Haploidy; Interphase; Methyl Methanesulfonate; Spectrometry, Fluorescence; Ultraviolet Rays | 1980 |
The role of umuC gene product in mutagenesis by simple alkylating agents.
Topics: Alkylating Agents; DNA Repair; DNA, Bacterial; Dose-Response Relationship, Drug; Escherichia coli; Ethyl Methanesulfonate; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mutagens; Mutation; Ultraviolet Rays | 1980 |
Mutagenic interactions between near-ultraviolet (365 nm) radiation and alkylating agents in Escherichia coli.
Topics: DNA Repair; Dose-Response Relationship, Radiation; Escherichia coli; Ethyl Methanesulfonate; Methyl Methanesulfonate; Mutagenicity Tests; Mutagens; Mutation; Phenotype; Ultraviolet Rays | 1981 |
Role of the uvrE gene product and of inducible O6-methylguanine removal in the induction of mutations by N-methyl-N'-nitro-N-nitrosoguanidine in Escherichia coli.
Topics: Chloramphenicol; DNA Repair; DNA, Bacterial; Dose-Response Relationship, Drug; Escherichia coli; Ethyl Methanesulfonate; Guanine; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mutation; Protein Biosynthesis; Ultraviolet Rays | 1980 |
Pure and mosaic clones--a reflection of differences in mechanisms of mutagenesis by different agents in Saccharomyces cerevisiae.
Topics: DNA Repair; DNA Replication; Ethyl Methanesulfonate; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mosaicism; Mutation; Nitrous Acid; Saccharomyces cerevisiae | 1981 |
Influence of DNA-repair deficiencies on MMS- and EMS-induced mutagenesis in Escherichia coli K-12.
Topics: DNA Repair; DNA Replication; Escherichia coli; Ethyl Methanesulfonate; Methyl Methanesulfonate; Mutagens; Mutation; Phenotype | 1981 |
[Para-aminobenzoic acid intensification of DNA repair processes in Escherichia coli K-12].
Topics: 4-Aminobenzoic Acid; Aminobenzoates; DNA Repair; DNA, Bacterial; Drug Interactions; Escherichia coli; Ethyl Methanesulfonate; Ethylnitrosourea; Methyl Methanesulfonate; Methylnitrosourea; Stimulation, Chemical | 1982 |
A novel mutant of mouse lymphoma cells sensitive to alkylating agents and caffeine.
Topics: Alkylating Agents; Animals; Caffeine; Cell Survival; Ethyl Methanesulfonate; Leukemia L5178; Leukemia, Experimental; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mice; Mitomycins; Mutagenicity Tests; Mutagens; Mutation; Ultraviolet Rays | 1982 |
Molecular lesions involved in the induction of sister-chromatid exchange.
Topics: Animals; Anthramycin; Cell Line; Cricetinae; Cricetulus; Crossing Over, Genetic; Ethyl Methanesulfonate; Female; Methyl Methanesulfonate; Mutagenicity Tests; Mutagens; Ovary; Sister Chromatid Exchange | 1982 |
Role of deoxynucleoside triphosphate pools in the cytotoxic and mutagenic effects of DNA alkylating agents.
Topics: Alkylating Agents; Animals; Cell Line; Cell Survival; Cricetinae; Cricetulus; Cytidine Triphosphate; Cytosine Nucleotides; Ethyl Methanesulfonate; Female; Methyl Methanesulfonate; Mutagens; Ovary; Thymine Nucleotides | 1981 |
Persistence and accumulation of (potential) single-strand breaks in liver DNA of rats treated with ethyl methanesulphonate.
Topics: Alkylation; Animals; DNA; DNA Repair; DNA, Single-Stranded; Ethyl Methanesulfonate; Female; Liver; Methyl Methanesulfonate; Rats | 1981 |
[Structure-activity relationships in experimental neuro-oncology (author's transl)].
Topics: Animals; Carcinogens; Ethyl Methanesulfonate; Female; Maternal-Fetal Exchange; Methyl Methanesulfonate; Neoplasms, Experimental; Nervous System Neoplasms; Pregnancy; Rats; Structure-Activity Relationship | 1981 |
Relationship between chemical damage of DNA and mutations in mammalian cells. I. Dose-response curves for the induction of 6-thioguanine-resistant mutants by low doses of monofunctional alkylating agents, X-rays and UV radiation in V79 Chinese hamster cel
Topics: Animals; Cell Line; Cricetinae; Cricetulus; DNA; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Ethyl Methanesulfonate; Ethylnitrosourea; Lung; Methyl Methanesulfonate; Methylnitrosourea; Mutation; Ultraviolet Rays; X-Rays | 1980 |
DNA synthesis, mutagenesis, DNA damage, and cytotoxicity in cultured mammalian cells treated with alkylating agents.
Topics: Alkylating Agents; Animals; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; DNA; DNA Repair; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mice; Mutation | 1980 |
Methodological aspects of the white-ivory assay of Drosophila melanogaster.
Topics: Alkylating Agents; Animals; Cross-Linking Reagents; Drosophila melanogaster; Ethyl Methanesulfonate; Ethylnitrosourea; Evaluation Studies as Topic; Eye Color; Female; Hempa; Male; Methyl Methanesulfonate; Multigene Family; Mutagenicity Tests; Mutagens; Sex Characteristics; Species Specificity | 1995 |
Increased sensitivity to DNA-alkylating agents in CHO mutants with decreased poly(ADP-ribose) polymerase activity.
Topics: Alkylating Agents; Animals; Cell Survival; CHO Cells; Cricetinae; DNA Damage; Ethyl Methanesulfonate; Glycoside Hydrolases; Kinetics; Methyl Methanesulfonate; Mutagenesis; Mutagens; Mutation; NAD; Nuclear Proteins; Poly(ADP-ribose) Polymerases; RNA; Sulfuric Acid Esters | 1994 |
Effects of cinnamaldehyde on survival and formation of HGPRT- mutants in V79 cells treated with methyl methanesulfonate, N-nitroso-N-methylurea, ethyl methanesulfonate and UV light.
Topics: Acrolein; Animals; Cell Survival; Cricetinae; Cricetulus; DNA Repair; Ethyl Methanesulfonate; Hypoxanthine Phosphoribosyltransferase; Methyl Methanesulfonate; Methylnitrosourea; Mutagenicity Tests | 1994 |
A comparative study of TK6 human lymphoblastoid and L5178Y mouse lymphoma cell lines in the in vitro micronucleus test.
Topics: Animals; B-Lymphocytes; Cell Line; Cell Survival; Demecolcine; Ethyl Methanesulfonate; Humans; Leukemia L5178; Lymphoma; Methyl Methanesulfonate; Mice; Micronucleus Tests; Mitomycin; Mutagens; Tumor Cells, Cultured; Vincristine; X-Rays | 1995 |
Toxicity of four alkylating agents on in vitro rat embryo differentiation and development.
Topics: Abnormalities, Drug-Induced; Animals; Cell Differentiation; Cells, Cultured; Central Nervous System; Dose-Response Relationship, Drug; Embryonic and Fetal Development; Ethyl Methanesulfonate; Ethylnitrosourea; Female; Forelimb; Methyl Methanesulfonate; Methylnitrosourea; Rats | 1995 |
Increased resistance of the Chinese hamster mutant irs1 cells to monofunctional alkylating agents by transfection of the E. coli or mammalian N3-methyladenine-DNA-glycosylase genes.
Topics: Adenine; Alkylating Agents; Animals; Cell Line; Cricetinae; Dexamethasone; DNA; DNA Glycosylases; DNA Repair; Drug Resistance; Escherichia coli; Ethyl Methanesulfonate; Methyl Methanesulfonate; N-Glycosyl Hydrolases; Rats; Transfection | 1993 |
Somatic reversion of some copia-like induced mutations, at the white locus of Drosophila melanogaster, after treatment with alkylating agents.
Topics: Alkylating Agents; Animals; DNA Transposable Elements; Drosophila melanogaster; Ethyl Methanesulfonate; Ethylnitrosourea; Eye Color; Male; Methyl Methanesulfonate; Mutagenesis, Insertional; Mutagenesis, Site-Directed; Mutagenicity Tests; Suppression, Genetic | 1995 |
Spectrum of mutations induced by methyl and ethyl methanesulfonate at the hprt locus of normal and tag expressing Chinese hamster fibroblasts.
Topics: Alkylation; Animals; Base Sequence; Cell Line; Cricetinae; Cricetulus; DNA Glycosylases; DNA Primers; DNA Repair; Ethyl Methanesulfonate; Hypoxanthine Phosphoribosyltransferase; Methyl Methanesulfonate; Molecular Sequence Data; Mutagenesis; N-Glycosyl Hydrolases; Thioguanine; Transfection | 1995 |
[The repair of UV-induced postreplication DNA gaps in Escherichia coli cells adapted to methylmethane sulfonate and ethylmethane sulfonate].
Topics: Adaptation, Physiological; DNA Damage; DNA Repair; DNA Replication; DNA, Bacterial; Escherichia coli; Ethyl Methanesulfonate; Genotype; Methyl Methanesulfonate; Molecular Weight; SOS Response, Genetics; Ultraviolet Rays | 1994 |
Effects of spermine on formation of HGPRT- mutants induced by ethylmethanesulfonate, methylmethanesulfonate, and mitomycin C in V79 Chinese hamster cells.
Topics: Alkylation; Animals; Antimutagenic Agents; Binding, Competitive; Cells, Cultured; Cricetinae; Cricetulus; Ethyl Methanesulfonate; Glutathione; Glutathione Transferase; Hypoxanthine Phosphoribosyltransferase; Lung; Methyl Methanesulfonate; Mitomycin; Mutagenesis; Mutagenicity Tests; Mutagens; Spermine | 1994 |
Effect of ogt expression on mutation induction by methyl-, ethyl- and propylmethanesulphonate in Escherichia coli K12 strains.
Topics: Alkylating Agents; Escherichia coli; Ethyl Methanesulfonate; Gene Expression; Genes, Bacterial; Mesylates; Methyl Methanesulfonate; Mutagenesis; Mutation; Sequence Deletion | 1994 |
Comparison of effects of direct-acting DNA methylating and ethylating agents on inducible gene expression in vivo.
Topics: Alkylating Agents; Animals; Carcinogens; Chick Embryo; DNA; DNA Damage; Enzyme Induction; Ethyl Methanesulfonate; Ethylnitrosourea; Genes; Methyl Methanesulfonate; Methylation; Methylnitrosourea; Mutagenesis, Site-Directed; Phosphoenolpyruvate Carboxykinase (GTP) | 1994 |
DNA damaging agents increase the stability of interleukin-1 alpha, interleukin-1 beta, and interleukin-6 transcripts and the production of the relative proteins.
Topics: Carcinogens; Cells, Cultured; DNA Damage; Ethyl Methanesulfonate; Gene Expression Regulation; Humans; Interleukin-1; Interleukin-6; Methyl Methanesulfonate; Mitomycin; Monocytes; RNA, Messenger; Transcription, Genetic | 1994 |
Increased removal of 3-alkyladenine reduces the frequencies of hprt mutations induced by methyl- and ethylmethanesulfonate in Chinese hamster fibroblast cells.
Topics: Adenine; Alkylation; Animals; Blotting, Southern; CHO Cells; Cricetinae; Cricetulus; DNA Glycosylases; Escherichia coli; Ethyl Methanesulfonate; Hypoxanthine Phosphoribosyltransferase; Kinetics; Methyl Methanesulfonate; Mutation; N-Glycosyl Hydrolases | 1994 |
The human immunodeficiency virus type 1 long terminal repeat is activated by monofunctional and bifunctional DNA alkylating agents in human lymphocytes.
Topics: Alkylating Agents; Base Sequence; Cell Line; Chloramphenicol O-Acetyltransferase; Ethyl Methanesulfonate; HIV Long Terminal Repeat; HIV-1; Humans; Lymphocytes; Methyl Methanesulfonate; Mitomycin; Molecular Sequence Data; Mutagens; NF-kappa B; Nuclear Proteins; Sp1 Transcription Factor; Virus Activation | 1993 |
Antimutagenic investigations on commercial yogurt.
Topics: Antimutagenic Agents; Bifidobacterium; Ethyl Methanesulfonate; Gene Conversion; Lactobacillus; Methyl Methanesulfonate; Microbial Sensitivity Tests; Saccharomyces cerevisiae; Streptococcus; Yogurt | 1993 |
Statistical confirmation that immunofluorescent detection of DNA repair in human fibroblasts by measurement of bromodeoxyuridine incorporation is stoichiometric and sensitive.
Topics: Bromodeoxyuridine; Cells, Cultured; DNA; DNA Repair; Ethyl Methanesulfonate; Fibroblasts; Flow Cytometry; Fluorescent Antibody Technique; Humans; Methyl Methanesulfonate; Sensitivity and Specificity; Ultraviolet Rays | 1993 |
Cloning of rat GADD45 gene and induction analysis following ionizing radiation in vivo.
Topics: Alkylating Agents; Amino Acid Sequence; Animals; Base Sequence; Cell Line; Cloning, Molecular; DNA Damage; Ethyl Methanesulfonate; GADD45 Proteins; Gamma Rays; Gene Expression Regulation; Genes; Intracellular Signaling Peptides and Proteins; Liver; Male; Methyl Methanesulfonate; Molecular Sequence Data; Organ Specificity; Proteins; Rats; Rats, Wistar; RNA, Messenger; Sequence Analysis, DNA | 1996 |
The alkaline comet test on plant cells: a new genotoxicity test for DNA strand breaks in Vicia faba root cells.
Topics: Cadmium; Cadmium Chloride; Chlorides; Chromium Compounds; Cycloheximide; DNA Damage; Electrophoresis, Agar Gel; Ethyl Methanesulfonate; Fabaceae; Genetic Techniques; Methyl Methanesulfonate; Mitomycin; Models, Statistical; Mutagenicity Tests; Plant Roots; Plants, Medicinal; Protein Synthesis Inhibitors; Software | 1996 |
[A strain of the yeast Saccharomyces cerevisiae for testing environmental mutagens based on interaction of the mutations rad2 and him1].
Topics: DNA Repair; Endonucleases; Environmental Monitoring; Ethyl Methanesulfonate; Genes, Fungal; Genetic Code; Methyl Methanesulfonate; Mutagenicity Tests; Mutagens; Mutation; Saccharomyces cerevisiae; Ultraviolet Rays | 1996 |
Alkaline single-cell gel (comet) assay and genotoxicity monitoring using two species of tadpoles.
Topics: Animals; Animals, Laboratory; Bufonidae; DNA; DNA Damage; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Genetic Techniques; Glycoproteins; Methyl Methanesulfonate; Mutagenicity Tests; Mutagens; Ontario; Ranidae; Reproducibility of Results; Sensitivity and Specificity | 1996 |
Comparison of inhibition of glucose-stimulated insulin secretion in rat islets of Langerhans by streptozotocin and methyl and ethyl nitrosoureas and methanesulphonates. Lack of correlation with nitric oxide-releasing or O6-alkylating ability.
Topics: Alkylating Agents; Animals; Cyclic GMP; Ethyl Methanesulfonate; Ethylnitrosourea; Glucose; Guanine; Insulin; Islets of Langerhans; Methyl Methanesulfonate; Methylnitrosourea; Nitric Oxide; Rats; Rats, Sprague-Dawley; Streptozocin; Structure-Activity Relationship | 1995 |
Molecular study of the germinal reversions induced at the white-ivory locus in Drosophila melanogaster.
Topics: Alkylating Agents; Animals; Blotting, Southern; Drosophila melanogaster; Ethyl Methanesulfonate; Ethylnitrosourea; Eye Color; Germ-Line Mutation; Methyl Methanesulfonate; Mutagenicity Tests; Phenotype; Polymerase Chain Reaction | 1996 |
Methanethiosulfonate derivatives inhibit current through the ryanodine receptor/channel.
Topics: Animals; Calcium Channels; Cytoplasm; Ethyl Methanesulfonate; In Vitro Techniques; Ion Channels; Lipid Bilayers; Methyl Methanesulfonate; Microsomes; Muscle Proteins; Muscles; Rabbits; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sulfhydryl Compounds; Thiosulfates | 1997 |
Germ-cell mutagenesis in lambda lacZ transgenic mice treated with ethylating and methylating agents: comparison with specific-locus test.
Topics: Animals; Bacteriophage lambda; Epididymis; Ethyl Methanesulfonate; Ethylnitrosourea; Lac Operon; Male; Methyl Methanesulfonate; Methylnitrosourea; Mice; Mice, Transgenic; Mutagenesis; Mutagenicity Tests; Mutagens; Spermatozoa; Vas Deferens | 1997 |
Sources of variability in data from a positive selection lacZ transgenic mouse mutation assay: an interlaboratory study.
Topics: Animals; Data Interpretation, Statistical; Ethyl Methanesulfonate; Ethylnitrosourea; International Cooperation; Laboratories; Lac Operon; Male; Mesylates; Methyl Methanesulfonate; Methylnitrosourea; Mice; Mice, Transgenic; Mutagenicity Tests; Mutagens; Spermatozoa | 1997 |
Cytotoxic and mutagenic responses to X-rays and chemical mutagens in normal and p53-mutated human lymphoblastoid cells.
Topics: Cell Line; Chromosome Breakage; Chromosome Deletion; DNA Fingerprinting; Ethyl Methanesulfonate; Genes, p53; Humans; Lymphocytes; Methyl Methanesulfonate; Mitomycin; Mutagens; X-Rays | 1997 |
The mus206 gene of Drosophila melanogaster is required in the excision repair of alkylation-induced DNA lesions.
Topics: Alkylating Agents; Animals; Chromosome Mapping; DNA; DNA Repair; Drosophila melanogaster; Embryo, Nonmammalian; Ethyl Methanesulfonate; Female; Genes, Insect; Genetic Techniques; Glycoproteins; Male; Methyl Methanesulfonate; Mutation; Recombination, Genetic | 1997 |
A genetic system to detect mitotic recombination between repeated chromosomal sequences in Drosophila Schneider line 2 cells.
Topics: Animals; beta-Galactosidase; Cells, Cultured; Chromosomes; Drosophila melanogaster; Drug Resistance; Escherichia coli; Ethyl Methanesulfonate; Flow Cytometry; Genes, Reporter; Gentamicins; Methyl Methanesulfonate; Mitomycin; Mitosis; Mutagenicity Tests; Mutagens; Polymerase Chain Reaction; Recombination, Genetic; Repetitive Sequences, Nucleic Acid; Transgenes | 1997 |
Induced somatic and germinal reversion of the white-spotted-1 insertional mutant phenotype in Drosophila melanogaster.
Topics: Animals; ATP-Binding Cassette Transporters; Drosophila melanogaster; Drosophila Proteins; Ethyl Methanesulfonate; Ethylnitrosourea; Eye Proteins; Female; Germ-Line Mutation; Insect Proteins; Larva; Male; Methyl Methanesulfonate; Mutagenesis, Insertional; Mutation; Phenotype; Retroelements | 1998 |
Evaluation of P19 cells for studying mechanisms of developmental toxicity: application to four direct-acting alkylating agents.
Topics: Alkylating Agents; Aminobutyrates; Animals; Antineoplastic Agents, Alkylating; Carcinoma, Embryonal; Cell Differentiation; Cell Division; Dimethyl Sulfoxide; Ethyl Methanesulfonate; Ethylnitrosourea; gamma-Aminobutyric Acid; Male; Mesencephalon; Methyl Methanesulfonate; Methylnitrosourea; Mice; Neurons; Tretinoin; Tumor Cells, Cultured | 1998 |
Effects of O6-benzylguanine on growth and differentiation of P19 embryonic carcinoma cells treated with alkylating agents.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Carcinogens; Carcinoma, Embryonal; Cell Differentiation; Cell Division; Cell Survival; DNA Repair; Ethyl Methanesulfonate; Ethylnitrosourea; Guanine; Mesencephalon; Methyl Methanesulfonate; Methylnitrosourea; Mice; Neurons; O(6)-Methylguanine-DNA Methyltransferase; Rats; Tretinoin; Tumor Cells, Cultured | 1998 |
Adaptive response to low dose of EMS or MMS in human peripheral blood lymphocytes.
Topics: Adaptation, Physiological; Adult; Alkylating Agents; Ethyl Methanesulfonate; Humans; In Vitro Techniques; Lymphocytes; Male; Methyl Methanesulfonate; Sister Chromatid Exchange | 1998 |
Comparison of DNA damage in plants as measured by single cell gel electrophoresis and somatic leaf mutations induced by monofunctional alkylating agents.
Topics: Alkylating Agents; DNA Damage; DNA, Plant; Electrophoresis; Environmental Monitoring; Ethyl Methanesulfonate; Ethylnitrosourea; Methyl Methanesulfonate; Methylnitrosourea; Mutagens; Nicotiana; Nucleic Acid Conformation; Plant Leaves; Plant Roots; Plants, Toxic | 1999 |
Cell division transforms mutagenic lesions into deletion-recombinagenic lesions in yeast cells.
Topics: 4-Nitroquinoline-1-oxide; CDC28 Protein Kinase, S cerevisiae; Cell Division; Chromosome Deletion; DNA, Fungal; Ethyl Methanesulfonate; Fungal Proteins; G1 Phase; G2 Phase; Gamma Rays; Methyl Methanesulfonate; Mutagenesis; Mutagenicity Tests; Mutagens; Point Mutation; Quinolones; Recombination, Genetic; Saccharomyces cerevisiae; Ultraviolet Rays | 1999 |
Isolating DNA repair mutants of Drosophila melanogaster.
Topics: Animals; Chromosome Mapping; Crosses, Genetic; DNA Repair; Drosophila melanogaster; Ethyl Methanesulfonate; Female; Genetic Techniques; Male; Methyl Methanesulfonate; Mutagenesis; Mutagens; Oviposition; X Chromosome | 1999 |
Modulation of chemical carcinogen-induced unscheduled DNA synthesis by dehydroepiandrosterone (DHEA) in the primary rat hepatocytes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinogens; Dehydroepiandrosterone; DNA; Ethyl Methanesulfonate; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Male; Methyl Methanesulfonate; Rats; Rats, Sprague-Dawley | 1999 |
Induction of an adaptive response in Drosophila imaginal disc cells exposed in vivo to low doses of alkylating agents.
Topics: Alkylating Agents; Animals; Crosses, Genetic; Dose-Response Relationship, Drug; Drosophila; Ethyl Methanesulfonate; Ethylnitrosourea; Larva; Methyl Methanesulfonate; Mutagenicity Tests; Mutagens; Wings, Animal | 2000 |
Cysteine residues and the structure of the rat renal proximal tubular type II sodium phosphate cotransporter (rat NaPi IIa).
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Carrier Proteins; Cysteine; Disulfides; Ethyl Methanesulfonate; Kidney Tubules, Proximal; Mesylates; Methyl Methanesulfonate; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Protein Structure, Tertiary; Rats; Reducing Agents; Serine; Sodium-Phosphate Cotransporter Proteins; Sodium-Phosphate Cotransporter Proteins, Type II; Sodium-Phosphate Cotransporter Proteins, Type IIa; Symporters; Xenopus laevis | 2000 |
Simultaneous measurement of the frequencies of intrachromosomal recombination and chromosome gain using the yeast DEL assay.
Topics: Aneuploidy; Benomyl; Chloral Hydrate; Chromosomes, Fungal; Dactinomycin; Ethyl Methanesulfonate; Flow Cytometry; Methotrexate; Methyl Methanesulfonate; Mutagens; Recombination, Genetic; Saccharomyces cerevisiae | 2000 |
Neisseria gonorrhoeae recJ mutants show defects in recombinational repair of alkylated bases and UV-induced pyrimidine dimers.
Topics: Alkylation; Alleles; Bacterial Proteins; Base Sequence; Blotting, Southern; Cloning, Molecular; DNA Repair; Dose-Response Relationship, Radiation; Escherichia coli; Escherichia coli Proteins; Ethyl Methanesulfonate; Exodeoxyribonucleases; Methyl Methanesulfonate; Models, Genetic; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutagens; Mutation; Neisseria gonorrhoeae; Phenotype; Pyrimidines; Recombination, Genetic; Time Factors; Transformation, Genetic; Ultraviolet Rays | 2000 |
Relative importance of transport and alkylation for pancreatic beta-cell toxicity of streptozotocin.
Topics: 3-O-Methylglucose; Alkylating Agents; Alkylation; Animals; Biological Transport; Biotransformation; Cell Line; Cell Survival; Ethyl Methanesulfonate; Ethylnitrosourea; Glucose Transporter Type 2; Islets of Langerhans; Kinetics; Methyl Methanesulfonate; Methylnitrosourea; Monosaccharide Transport Proteins; Rats; Recombinant Proteins; Streptozocin; Transfection | 2000 |
The relationship between alkylation of specific DNA bases and induction of sister chromatid exchange.
Topics: Alkylating Agents; Alkylation; Animals; Cell Line; Cricetinae; Cricetulus; DNA; DNA Methylation; Ethyl Methanesulfonate; Ethylnitrosourea; Methyl Methanesulfonate; Methylnitrosourea; Mutagens; Sister Chromatid Exchange | 1980 |
Flexibility of the Kir6.2 inward rectifier K(+) channel pore.
Topics: Amino Acid Sequence; Animals; Cadmium; COS Cells; Cysteine; Dimerization; Ethyl Methanesulfonate; Indicators and Reagents; Mesylates; Methyl Methanesulfonate; Models, Biological; Models, Molecular; Molecular Sequence Data; Pliability; Point Mutation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Conformation; Quaternary Ammonium Compounds; Sequence Homology, Amino Acid | 2001 |
Repairability during G1 of lesions eliciting sister chromatid exchanges induced by methylmethanesulfonate or ethylmethanesulfonate in bromodeoxyuridine-substituted and unsubstituted DNA strands.
Topics: Animals; Bromodeoxyuridine; Cells, Cultured; DNA; DNA Damage; DNA Repair; Ethyl Methanesulfonate; G1 Phase; Methyl Methanesulfonate; Mice; Mutagenicity Tests; Mutagens; Salivary Glands; Sister Chromatid Exchange | 2003 |
Trace analysis of residual methyl methanesulfonate, ethyl methanesulfonate and isopropyl methanesulfonate in pharmaceuticals by capillary gas chromatography with flame ionization detection.
Topics: Chromatography, Gas; Ethyl Methanesulfonate; Mesylates; Methyl Methanesulfonate; Pharmaceutical Preparations; Reproducibility of Results; Sensitivity and Specificity | 2004 |
[TK locus mutation assay: comparison of L5178Y and TK6 cell lines].
Topics: Animals; Cell Line, Tumor; Ethyl Methanesulfonate; Humans; Leukemia L5178; Lymphoma; Methyl Methanesulfonate; Mice; Mitomycin; Mutagenicity Tests; Mutation; Thymidine Kinase | 2004 |
Comparative study of the comet assay and the micronucleus test in amphibian larvae (Xenopus laevis) using benzo(a)pyrene, ethyl methanesulfonate, and methyl methanesulfonate: establishment of a positive control in the amphibian comet assay.
Topics: Animals; Benzo(a)pyrene; Comet Assay; Control Groups; DNA Damage; Ethyl Methanesulfonate; Female; Male; Methyl Methanesulfonate; Micronucleus Tests; Mutagens; Reference Values; Xenopus laevis | 2005 |
HIM1, a new yeast Saccharomyces cerevisiae gene playing a role in control of spontaneous and induced mutagenesis.
Topics: Chromosomes, Fungal; Epistasis, Genetic; Ethyl Methanesulfonate; Genes, Fungal; Methyl Methanesulfonate; Mutagenesis; Mutagens; Mutation; Nitrous Acid; Open Reading Frames; Physical Chromosome Mapping; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Ultraviolet Rays | 2005 |
Validation of Drosophila melanogaster as an in vivo model for genotoxicity assessment using modified alkaline Comet assay.
Topics: Alkylating Agents; Animals; Comet Assay; Cyclophosphamide; DNA Damage; Dose-Response Relationship, Drug; Drosophila melanogaster; Ethyl Methanesulfonate; Ethylnitrosourea; Larva; Methyl Methanesulfonate; Mutagenicity Tests; Mutagens; Sensitivity and Specificity | 2005 |
Evaluation of the alkaline Comet assay conducted with the wetlands plant Bacopa monnieri L. as a model for ecogenotoxicity assessment.
Topics: Bacopa; Cell Nucleus; Comet Assay; DNA Damage; DNA, Plant; Dose-Response Relationship, Drug; Environmental Monitoring; Environmental Pollutants; Ethyl Methanesulfonate; Methyl Methanesulfonate; Models, Biological; Mutagens; Plant Leaves; Sensitivity and Specificity | 2006 |
Mechanistic influences for mutation induction curves after exposure to DNA-reactive carcinogens.
Topics: Alkylating Agents; Cell Line; Chromosome Aberrations; DNA; DNA Adducts; DNA Damage; Ethyl Methanesulfonate; Ethylnitrosourea; Humans; Hypoxanthine Phosphoribosyltransferase; Lymphocytes; Methyl Methanesulfonate; Methylnitrosourea; Mutagens; Point Mutation | 2007 |
Control of inward rectifier K channel activity by lipid tethering of cytoplasmic domains.
Topics: Bacterial Proteins; Burkholderia pseudomallei; Cell-Free System; Cloning, Molecular; Cysteine; Ethyl Methanesulfonate; Ion Channel Gating; Membrane Lipids; Mesylates; Methyl Methanesulfonate; Models, Molecular; Mutation; Potassium Channels, Inwardly Rectifying; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Rubidium Radioisotopes; Sulfhydryl Reagents | 2007 |
Role of DNA mismatch repair and double-strand break repair in genome stability and antifungal drug resistance in Candida albicans.
Topics: Candida albicans; DNA; DNA Damage; DNA Repair; Drug Resistance; Drug Resistance, Fungal; Ethyl Methanesulfonate; Genome; Heterozygote; Hydrogen Peroxide; Methyl Methanesulfonate; Models, Biological; Mutation; Saccharomyces cerevisiae; Ultraviolet Rays | 2007 |
Detection of excision repaired DNA damage in the comet assay by using Ara-C and hydroxyurea in three different cell types.
Topics: Blood Cells; Cell Line; Cell Survival; Comet Assay; Cytarabine; DNA Damage; DNA Repair; Ethyl Methanesulfonate; Humans; Hydroxyurea; Methyl Methanesulfonate | 2009 |
Development and validation of GC-MS method for the determination of methyl methanesulfonate and ethyl methanesulfonate in imatinib mesylate.
Topics: Benzamides; Drug Contamination; Ethyl Methanesulfonate; Gas Chromatography-Mass Spectrometry; Imatinib Mesylate; Methyl Methanesulfonate; Piperazines; Pyrimidines | 2008 |
EMS in Viracept--initial ('traditional') assessment of risk to patients based on linear dose response relations.
Topics: Abnormalities, Drug-Induced; Animals; Antineoplastic Agents, Alkylating; Carcinogenicity Tests; Dose-Response Relationship, Drug; Drug Contamination; Ethyl Methanesulfonate; Female; Genes, Dominant; Genes, Lethal; Germ-Line Mutation; HIV Protease Inhibitors; Humans; Linear Models; Mammary Neoplasms, Animal; Methyl Methanesulfonate; Mice; Mutagenicity Tests; Nelfinavir; No-Observed-Adverse-Effect Level; Pregnancy; Quantitative Structure-Activity Relationship; Rats; Risk Assessment | 2009 |
Mutagenicity of N-ethyl-N-nitrosourea, N-methyl-N-nitrosourea, methyl methanesulfonate and ethyl methanesulfonate in the developing Syrian hamster fetus.
Topics: Animals; Cricetinae; Ethyl Methanesulfonate; Ethylnitrosourea; Female; Fetus; Maternal-Fetal Exchange; Mesocricetus; Methyl Methanesulfonate; Methylnitrosourea; Mutagenicity Tests; Mutagens; Pregnancy; Pregnancy, Animal | 2010 |
Sensitivity of Bidens laevis L. to mutagenic compounds. Use of chromosomal aberrations as biomarkers of genotoxicity.
Topics: Bidens; Biological Assay; Chromosome Aberrations; Environmental Monitoring; Ethyl Methanesulfonate; Maleic Hydrazide; Methyl Methanesulfonate; Mutagenicity Tests; Mutagens; Seeds; Wetlands | 2011 |
Low level determinations of methyl methanesulfonate and ethyl methanesulfonate impurities in Lopinavir and Ritonavir Active pharmaceutical ingredients by LC/MS/MS using electrospray ionization.
Topics: Chromatography, Liquid; Ethyl Methanesulfonate; HIV Protease Inhibitors; Limit of Detection; Lopinavir; Methyl Methanesulfonate; Pyrimidinones; Reference Standards; Ritonavir; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2011 |
Brahmarasayana protects against Ethyl methanesulfonate or Methyl methanesulfonate induced chromosomal aberrations in mouse bone marrow cells.
Topics: Animals; Bone Marrow Cells; Cells, Cultured; Chromosome Aberrations; DNA Damage; DNA Repair; Ethyl Methanesulfonate; Humans; Male; Methyl Methanesulfonate; Mice; Plant Preparations; Plants, Medicinal | 2012 |
Insensitivity of the in vitro cytokinesis-block micronucleus assay with human lymphocytes for the detection of DNA damage present at the start of the cell culture.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Cell Culture Techniques; Cell Nucleus; Cells, Cultured; Comet Assay; Cytokinesis; DNA Damage; Epoxy Compounds; Ethyl Methanesulfonate; Ethylnitrosourea; Female; Humans; Lymphocytes; Male; Methyl Methanesulfonate; Micronucleus Tests; Mitomycin; Mutagenicity Tests; Mutagens | 2012 |
Characterization of formaldehyde's genotoxic mode of action by gene expression analysis in TK6 cells.
Topics: Antineoplastic Agents, Phytogenic; Cell Line; Cell Survival; Coloring Agents; Comet Assay; Demecolcine; Down-Regulation; Ethyl Methanesulfonate; Formaldehyde; Gene Expression; Genes, p53; Humans; Methyl Methanesulfonate; Microarray Analysis; Mutagens; Up-Regulation; Vincristine | 2013 |
A combination of in vitro comet assay and micronucleus test using human lymphoblastoid TK6 cells.
Topics: Cell Survival; Cells, Cultured; Comet Assay; Cross-Linking Reagents; Cytotoxins; Ethyl Methanesulfonate; Gamma Rays; Humans; Hydrogen Peroxide; Methyl Methanesulfonate; Micronucleus Tests; Mitomycin; Mutagenicity Tests; Mutagens; Octoxynol; Sensitivity and Specificity | 2013 |
Quantitative assessment of the dose-response of alkylating agents in DNA repair proficient and deficient ames tester strains.
Topics: Alkylating Agents; Dacarbazine; DNA Helicases; DNA Repair; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Methyl Methanesulfonate; Methylnitrosourea; Methyltransferases; Mutagenicity Tests; Mutagens; Salmonella typhimurium; Species Specificity; Temozolomide | 2014 |
Derivation of point of departure (PoD) estimates in genetic toxicology studies and their potential applications in risk assessment.
Topics: Animals; Benchmarking; Databases, Factual; Dose-Response Relationship, Drug; Ecotoxicology; Ethyl Methanesulfonate; Ethylnitrosourea; Humans; Methyl Methanesulfonate; Methylnitrosourea; Mutagens; No-Observed-Adverse-Effect Level; Risk Assessment | 2014 |
Vehicle and positive control values from the in vivo rodent comet assay and biomonitoring studies using human lymphocytes: historical database and influence of technical aspects.
Topics: Animals; Comet Assay; Ethyl Methanesulfonate; Female; Freezing; Humans; Lymphocytes; Male; Methyl Methanesulfonate; Mice, Inbred ICR; Organ Specificity; Rats, Sprague-Dawley; Reproducibility of Results; Rodentia; Tail | 2014 |
Inter-laboratory comparison of the in vivo comet assay including three image analysis systems.
Topics: Animals; Comet Assay; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Image Processing, Computer-Assisted; Jejunum; Liver; Male; Methyl Methanesulfonate; Propidium; Rats, Wistar; Sensitivity and Specificity | 2015 |
Determination of sulfonate ester genotoxic impurities in imatinib mesylate by gas chromatography with mass spectrometry.
Topics: Drug Contamination; Ethyl Methanesulfonate; Gas Chromatography-Mass Spectrometry; Imatinib Mesylate; Methyl Methanesulfonate; Mutagens | 2016 |
Determination of methyl methanesulfonate and ethyl methanesulfonate in methanesulfonic acid by derivatization followed by high-performance liquid chromatography with ultraviolet detection.
Topics: Chromatography, High Pressure Liquid; Drug Contamination; Ethyl Methanesulfonate; Mesylates; Methyl Methanesulfonate | 2017 |
Antimutagenic action of the live yeast can be transmitted to the offspring of Drosophila melanogaster. A genetic study using the wing spot assay.
Topics: Animals; Biological Assay; Chromium Compounds; Drosophila melanogaster; Ethyl Methanesulfonate; Female; Fertility; Gamma Rays; Male; Methyl Methanesulfonate; Methylnitrosourea; Mutagens; Mutation; Saccharomyces cerevisiae; Wings, Animal | 2018 |