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ethyl methanesulfonate and guanine

ethyl methanesulfonate has been researched along with guanine in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19903 (17.65)18.7374
1990's12 (70.59)18.2507
2000's1 (5.88)29.6817
2010's1 (5.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anderson, MW; Darden, TA; Foley, CK; Glickman, BW; Pedersen, LG1
Henderson, L; O'Donovan, MR; Waters, R; Wilcox, P1
Bochert, G; Neubert, D; Platzek, T; Rahm, U1
Ehling, UH; Mohn, GR; Neuhäuser-Klaus, A; van Zeeland, AA1
Sklar, R; Strauss, B1
Jansen, JG; Mohn, GR; Tates, AD; van Teijlingen, CM; van Zeeland, AA; Vrieling, H1
Bochert, G; Meister, R; Neubert, D; Platzek, T1
Kohalmi, SE; Kunz, BA; Roche, HM1
Bignami, M; Calcagnile, A; Di Muccio, A; Dogliotti, E; Fortini, P1
Furusho, K; Gerson, SL; Kubota, M; Liu, L; Wakazono, Y1
Cunningham, JM; Delaney, CA; Di Matteo, M; Dunger, A; Green, IC; Green, MH1
Jansen, JG; Op het Veld, CW; van Hees-Stuivenberg, S; van Zeeland, AA1
Baan, RA; Berends, F; Bergmans, A; Borsboom, Y; Lohman, PH; Luiten-Schuite, A; Mientjes, EJ; van Delft, JH; van der Wolf, E1
Faustman, EM; Seeley, MR1
Branda, RF; Lafayette, AR; Nicklas, JA; O'Neill, JP1
Bochert, G; Platzek, T1
Katanić, J; Matić, S; Mihailović, V; Mladenović, M; Solujić, S; Stanić, S; Stanković, N1

Reviews

1 review(s) available for ethyl methanesulfonate and guanine

ArticleYear
Embryotoxicity induced by alkylating agents: 7. Low dose prenatal-toxic risk estimation based on NOAEL risk factor approach, dose-response relationships, and DNA adducts using methylnitrosourea as a model compound.
    Teratogenesis, carcinogenesis, and mutagenesis, 1993, Volume: 13, Issue:3

    Topics: Abnormalities, Drug-Induced; Algorithms; Alkylating Agents; Alkylation; Animals; DNA; DNA Damage; Dose-Response Relationship, Drug; Embryo, Mammalian; Ethyl Methanesulfonate; Female; Fetal Death; Guanine; Methylnitrosourea; Mice; Models, Theoretical; Pregnancy; Risk Factors; Toxicology

1993

Other Studies

16 other study(ies) available for ethyl methanesulfonate and guanine

ArticleYear
Theoretical and experimental measures of DNA helix stability and their relation to sequence specific repair of O6-ethylguanine lesions.
    Mutation research, 1991, Volume: 255, Issue:1

    Topics: Base Sequence; DNA Damage; DNA Repair; DNA, Bacterial; Escherichia coli; Ethyl Methanesulfonate; Guanine; Kinetics; Molecular Sequence Data; Nucleic Acid Conformation; Thermodynamics

1991
DNA alkylations and mutation after exposure to ethyl methanesulphonate in mammalian cell lines routinely used in mutagenicity testing.
    Mutagenesis, 1990, Volume: 5 Suppl

    Topics: Adenine; Alkylation; Animals; Cell Line; Chromatography, High Pressure Liquid; DNA; DNA Damage; Ethyl Methanesulfonate; Guanine; Humans; Mutagenicity Tests; Mutagens; Mutation; Tritium

1990
Embryotoxicity induced by alkylating agents. Some methodological aspects of DNA alkylation studies in murine embryos using ethylmethanesulfonate.
    Zeitschrift fur Naturforschung. C, Journal of biosciences, 1987, Volume: 42, Issue:5

    Topics: Adenine; Alkylation; Animals; DNA; Embryo, Mammalian; Ethyl Methanesulfonate; Female; Guanine; Liver; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred Strains; Pregnancy; Spectrophotometry, Infrared; Structure-Activity Relationship

1987
Quantitative comparison of genetic effects of ethylating agents on the basis of DNA adduct formation. Use of O6-ethylguanine as molecular dosimeter for extrapolation from cells in culture to the mouse.
    Environmental health perspectives, 1985, Volume: 62

    Topics: Alkylating Agents; Animals; Cell Line; Cells, Cultured; Cricetinae; Cricetulus; DNA; Environmental Exposure; Escherichia coli; Ethyl Methanesulfonate; Ethylnitrosourea; Guanine; Lung; Methylnitronitrosoguanidine; Mice; Mutation; Structure-Activity Relationship; Sulfuric Acid Esters

1985
Role of the uvrE gene product and of inducible O6-methylguanine removal in the induction of mutations by N-methyl-N'-nitro-N-nitrosoguanidine in Escherichia coli.
    Journal of molecular biology, 1980, Nov-15, Volume: 143, Issue:4

    Topics: Chloramphenicol; DNA Repair; DNA, Bacterial; Dose-Response Relationship, Drug; Escherichia coli; Ethyl Methanesulfonate; Guanine; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mutation; Protein Biosynthesis; Ultraviolet Rays

1980
Marked differences in the role of O6-alkylguanine in hprt mutagenesis in T-lymphocytes of rats exposed in vivo to ethylmethanesulfonate, N-(2-hydroxyethyl)-N-nitrosourea, or N-ethyl-N-nitrosourea.
    Cancer research, 1995, May-01, Volume: 55, Issue:9

    Topics: Adenine; Animals; Base Composition; Base Sequence; Carcinogens; DNA Adducts; DNA, Complementary; Drug Resistance; Ethyl Methanesulfonate; Ethylnitrosourea; Guanine; Hypoxanthine Phosphoribosyltransferase; In Vitro Techniques; Male; Molecular Sequence Data; Mutagenesis; Point Mutation; Polymerase Chain Reaction; Rats; Rats, Inbred Lew; T-Lymphocytes; Thioguanine; Thymidine

1995
Elevated intracellular dCTP levels reduce the induction of GC-->AT transitions in yeast by ethyl methanesulfonate or N-methyl-N'-nitro-N- nitrosoguanidine but increase alkylation-induced GC-->CG transversions.
    Mutagenesis, 1993, Volume: 8, Issue:5

    Topics: Alkylation; Base Sequence; Deoxycytosine Nucleotides; DNA Mutational Analysis; DNA Repair; DNA Replication; DNA, Fungal; Ethyl Methanesulfonate; Genes, Fungal; Genes, Suppressor; Guanine; Methylnitronitrosoguanidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutagens; Nucleic Acid Heteroduplexes; Point Mutation; Saccharomyces cerevisiae; Thymine; Thymine Nucleotides

1993
Quantitative relationship between ethylated DNA bases and gene mutation at two loci in CHO cells.
    Environmental and molecular mutagenesis, 1993, Volume: 21, Issue:2

    Topics: Adenine; Alkylating Agents; Alkylation; Animals; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; DNA; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Ethylnitrosourea; Guanine; Hypoxanthine Phosphoribosyltransferase; Mutagenicity Tests; Mutation; Sodium-Potassium-Exchanging ATPase; Sulfuric Acid Esters

1993
Thymidine kinase deficient cells with decreased TTP pools are hypersensitive to DNA alkylating agents.
    Mutation research, 1996, Jan-02, Volume: 362, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Cell Survival; Ethyl Methanesulfonate; Guanine; HL-60 Cells; Humans; Hypoxanthine Phosphoribosyltransferase; Leukemia, T-Cell; Methylnitronitrosoguanidine; Methyltransferases; Mutagenesis; Mutagens; O(6)-Methylguanine-DNA Methyltransferase; Thymidine Kinase; Thymine Nucleotides; Tumor Cells, Cultured

1996
Comparison of inhibition of glucose-stimulated insulin secretion in rat islets of Langerhans by streptozotocin and methyl and ethyl nitrosoureas and methanesulphonates. Lack of correlation with nitric oxide-releasing or O6-alkylating ability.
    Biochemical pharmacology, 1995, Dec-22, Volume: 50, Issue:12

    Topics: Alkylating Agents; Animals; Cyclic GMP; Ethyl Methanesulfonate; Ethylnitrosourea; Glucose; Guanine; Insulin; Islets of Langerhans; Methyl Methanesulfonate; Methylnitrosourea; Nitric Oxide; Rats; Rats, Sprague-Dawley; Streptozocin; Structure-Activity Relationship

1995
Effect of nucleotide excision repair on hprt gene mutations in rodent cells exposed to DNA ethylating agents.
    Mutagenesis, 1997, Volume: 12, Issue:6

    Topics: Alkylating Agents; Animals; CHO Cells; Cricetinae; DNA; DNA Damage; DNA Mutational Analysis; DNA Repair; Ethyl Methanesulfonate; Ethylnitrosourea; Genes; Guanine; Hypoxanthine Phosphoribosyltransferase; Mutagenicity Tests; Mutagens; Mutation; Species Specificity; Thymine

1997
DNA adducts, mutant frequencies, and mutation spectra in various organs of lambda lacZ mice exposed to ethylating agents.
    Environmental and molecular mutagenesis, 1998, Volume: 31, Issue:1

    Topics: Animals; Bone Marrow; Brain; Diethylnitrosamine; DNA Adducts; Ethyl Methanesulfonate; Ethylnitrosourea; Female; Guanine; Lac Operon; Liver; Mice; Mice, Transgenic; Mutagens

1998
Effects of O6-benzylguanine on growth and differentiation of P19 embryonic carcinoma cells treated with alkylating agents.
    Teratogenesis, carcinogenesis, and mutagenesis, 1998, Volume: 18, Issue:3

    Topics: Alkylating Agents; Animals; Antineoplastic Agents; Carcinogens; Carcinoma, Embryonal; Cell Differentiation; Cell Division; Cell Survival; DNA Repair; Ethyl Methanesulfonate; Ethylnitrosourea; Guanine; Mesencephalon; Methyl Methanesulfonate; Methylnitrosourea; Mice; Neurons; O(6)-Methylguanine-DNA Methyltransferase; Rats; Tretinoin; Tumor Cells, Cultured

1998
The effect of folate deficiency on the hprt mutational spectrum in Chinese hamster ovary cells treated with monofunctional alkylating agents.
    Mutation research, 1999, Jun-30, Volume: 427, Issue:2

    Topics: Alkylating Agents; Animals; Base Pairing; CHO Cells; Cricetinae; DNA Mutational Analysis; DNA Primers; DNA Repair; Ethyl Methanesulfonate; Ethylnitrosourea; Folic Acid Deficiency; Guanine; Hypoxanthine Phosphoribosyltransferase; Mutagens; Mutation; Polymerase Chain Reaction; Thioguanine

1999
DNA alkylation studies of combined treatment with methylnitrosourea and ethylmethanesulfonate in mice.
    Teratogenesis, carcinogenesis, and mutagenesis, 2000, Volume: 20, Issue:1

    Topics: Alkylating Agents; Alkylation; Animals; DNA; DNA Damage; DNA Methylation; Drug Synergism; Embryo, Mammalian; Ethyl Methanesulfonate; Female; Guanine; Injections, Intraperitoneal; Liver; Male; Methylnitrosourea; Mice; Mice, Inbred Strains; Pregnancy

2000
Combining molecular docking and 3-D pharmacophore generation to enclose the in vivo antigenotoxic activity of naturally occurring aromatic compounds: myricetin, quercetin, rutin, and rosmarinic acid.
    Biochemical pharmacology, 2013, Nov-01, Volume: 86, Issue:9

    Topics: Alkylating Agents; Animals; Antimutagenic Agents; Binding Sites; Catalytic Domain; Cinnamates; Depsides; DNA Damage; Drosophila melanogaster; Ethyl Methanesulfonate; Flavonoids; Guanine; Male; Molecular Docking Simulation; Monte Carlo Method; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Quercetin; Rosmarinic Acid; Rutin; Thymine

2013