ethyl 4-isothiocyanatobutanoate has been researched along with caffeine in 1 studies
*Caffeine: A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes SMOOTH MUSCLE, stimulates CARDIAC MUSCLE, stimulates DIURESIS, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide PHOSPHODIESTERASES, antagonism of ADENOSINE RECEPTORS, and modulation of intracellular calcium handling. [MeSH]
*Caffeine: A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes SMOOTH MUSCLE, stimulates CARDIAC MUSCLE, stimulates DIURESIS, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide PHOSPHODIESTERASES, antagonism of ADENOSINE RECEPTORS, and modulation of intracellular calcium handling. [MeSH]
| Studies (ethyl 4-isothiocyanatobutanoate) | Trials (ethyl 4-isothiocyanatobutanoate) | Recent Studies (post-2010) (ethyl 4-isothiocyanatobutanoate) | Studies (caffeine) | Trials (caffeine) | Recent Studies (post-2010) (caffeine) |
|---|---|---|---|---|---|
| 7 | 0 | 0 | 25,501 | 2,393 | 6,825 |
| Protein | Taxonomy | ethyl 4-isothiocyanatobutanoate (IC50) | caffeine (IC50) |
|---|---|---|---|
| Acetylcholinesterase | Homo sapiens (human) | 7.25 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bartosova, Z; Bodo, J; Chalupa, I; Floch, L; Horakova, K; Jakubikova, J; Sedlak, J | 1 |
1 other study(ies) available for ethyl 4-isothiocyanatobutanoate and caffeine
| Article | Year |
|---|---|
Apoptotic effect of ethyl-4-isothiocyanatobutanoate is associated with DNA damage, proteasomal activity and induction of p53 and p21cip1/waf1.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Butyrates; Caffeine; Cell Cycle; Cell Cycle Proteins; Cell Line; Chromosome Aberrations; Cyclin-Dependent Kinase Inhibitor p21; DNA Damage; Flow Cytometry; Humans; Isothiocyanates; Leupeptins; Membrane Potential, Mitochondrial; Proteasome Endopeptidase Complex; Protein Serine-Threonine Kinases; Tumor Suppressor Protein p53 | 2006 |