ethoxyidazoxan has been researched along with idazoxan in 14 studies
| Studies (ethoxyidazoxan) | Trials (ethoxyidazoxan) | Recent Studies (post-2010) (ethoxyidazoxan) | Studies (idazoxan) | Trials (idazoxan) | Recent Studies (post-2010) (idazoxan) |
|---|---|---|---|---|---|
| 14 | 2 | 0 | 1,499 | 40 | 123 |
| Protein | Taxonomy | ethoxyidazoxan (IC50) | idazoxan (IC50) |
|---|---|---|---|
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.0083 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0195 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.0195 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.0537 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0195 | |
| Alpha-1A adrenergic receptor | Homo sapiens (human) | 2.884 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0195 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (78.57) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Griffin, IJ; Jackson, HC; Nutt, DJ | 2 |
| Birkett, SD; Griffin, IJ; Jackson, HC; Nutt, DJ | 1 |
| Convents, A; De Backer, JP; De Keyser, J; De Vos, H; Vauquelin, G | 1 |
| Ball, DM; Jackson, HC; Nutt, DJ | 1 |
| Hussain, JF; Kendall, DA; Pinthong, D; Wilson, VG | 1 |
| Bailey, JE; Coupland, NJ; Nutt, DJ; Potter, WZ; Wilson, SJ | 1 |
| Kyles, AE; Livingston, A; Waterman, AE | 1 |
| Clarke, RW; Harris, J | 1 |
| Mason, R; Mundey, MK; Wilson, VG | 1 |
| Folley, BS; Kim, HG; Oshinsky, RJ; Potter, WZ; Schmidt, ME; Schouten, JL | 1 |
| Colpaert, FC; Pauwels, PJ | 1 |
| Pauwels, PJ; Tardif, S | 1 |
| Cambridge, N; Robinson, ES | 1 |
2 trial(s) available for ethoxyidazoxan and idazoxan
| Article | Year |
|---|---|
A pharmacodynamic study of the alpha 2-adrenergic receptor antagonist ethoxyidazoxan in healthy volunteers.
Topics: Adrenergic alpha-Antagonists; Adult; Analysis of Variance; Blood Pressure; Body Temperature; Cross-Over Studies; Dioxanes; Double-Blind Method; Heart Rate; Humans; Idazoxan; Male; Norepinephrine; Platelet Aggregation; Platelet Aggregation Inhibitors; Saccades | 1994 |
Cerebral glucose metabolic and plasma catecholamine responses to the alpha(2) adrenoceptor antagonist ethoxyidazoxan given to healthy volunteers.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Adult; Blood Pressure; Brain Chemistry; Catecholamines; Epinephrine; Glucose; Humans; Idazoxan; Image Processing, Computer-Assisted; Imidazoline Receptors; Kinetics; Male; Norepinephrine; Receptors, Drug | 1999 |
12 other study(ies) available for ethoxyidazoxan and idazoxan
| Article | Year |
|---|---|
Alpha 2-adrenoceptor antagonists block the stimulant effects of cocaine in mice.
Topics: Adrenergic alpha-Antagonists; Animals; Cocaine; Dioxanes; Idazoxan; Male; Mice; Motor Activity | 1992 |
The effects of idazoxan and other alpha 2-adrenoceptor antagonists on urine output in the rat.
Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Idazoxan; Male; Quinolizines; Rats; Rats, Brattleboro; Rats, Wistar; Urodynamics; Yohimbine | 1992 |
Identification of alpha 2 adrenoceptors in the human nucleus olivarius by radioligand binding.
Topics: Adrenergic alpha-Agonists; Aged; Binding, Competitive; Brain Chemistry; Clonidine; Dioxanes; Epinephrine; Humans; Idazoxan; Middle Aged; Olivary Nucleus; Radioligand Assay; Receptors, Adrenergic, alpha | 1992 |
The effects of idazoxan and other alpha 2-adrenoceptor antagonists on food and water intake in the rat.
Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Dose-Response Relationship, Drug; Drinking; Eating; Idazoxan; Male; Quinolizines; Rats; Rats, Inbred Strains; Receptors, Drug | 1991 |
Noradrenergic mechanisms appear not to be involved in cocaine-induced seizures and lethality.
Topics: Adrenergic alpha-Antagonists; Animals; Cocaine; Desipramine; Dioxanes; Hyperkinesis; Idazoxan; Injections, Intraperitoneal; Mice; Norepinephrine; Seizures | 1990 |
Comparison of the interaction of agmatine and crude methanolic extracts of bovine lung and brain with alpha 2-adrenoceptor binding sites.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Agmatine; Animals; Binding, Competitive; Brimonidine Tartrate; Cattle; Cerebral Cortex; Clonidine; Dioxanes; Idazoxan; Imidazoles; Lung; Methanol; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Yohimbine | 1995 |
The spinal antinociceptive activity of the alpha 2-adrenoceptor agonist, xylazine in sheep.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Behavior, Animal; Dioxanes; Female; Idazoxan; Injections, Intravenous; Injections, Spinal; Pain Measurement; Pain Threshold; Sheep; Spinal Cord; Xylazine | 1993 |
Motor and cardiovascular effects of selective alpha 2-adrenoceptor antagonists in the decerebrated rabbit.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Decerebrate State; Dioxanes; Electric Stimulation; Female; Heart Rate; Idazoxan; Injections, Spinal; Male; Motor Neurons; Rabbits; Reflex; Retrospective Studies; Sural Nerve; Yohimbine | 1993 |
Selective potentiation by ouabain of naloxone-induced withdrawal contractions of isolated guinea-pig ileum following acute exposure to morphine.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Carbachol; Clonidine; Drug Synergism; Electric Stimulation; Enzyme Inhibitors; Guinea Pigs; Idazoxan; Ileum; In Vitro Techniques; Male; Morphine; Morphine Dependence; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Naloxone; Narcotic Antagonists; Ouabain; Receptors, Adrenergic, alpha-2; Sodium-Potassium-Exchanging ATPase; Substance Withdrawal Syndrome | 1998 |
Partial to complete antagonism by putative antagonists at the wild-type alpha(2C)-adrenoceptor based on kinetic analyses of agonist:antagonist interactions.
Topics: Adrenergic Agonists; Adrenergic Antagonists; Animals; Azepines; Brimonidine Tartrate; Calcium; CHO Cells; Clonidine; Cricetinae; DNA, Recombinant; Dose-Response Relationship, Drug; Drug Interactions; Epinephrine; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; Heterotrimeric GTP-Binding Proteins; Idazoxan; Kinetics; Medetomidine; Mice; Oxymetazoline; Quinoxalines; Rats; Receptors, Adrenergic, alpha-2; Recombinant Fusion Proteins; Transfection | 2000 |
Enhanced stability of wild-type and constitutively active alpha(2A)-adrenoceptors by ligands with agonist, silent and inverse agonist properties.
Topics: Adrenergic alpha-Antagonists; Animals; Binding Sites; CHO Cells; Cricetinae; Drug Interactions; GTP-Binding Proteins; Guanosine Triphosphate; Idazoxan; Imidazoles; Protein Binding; Radioligand Assay; Receptors, Adrenergic, alpha-2; Time Factors; Transfection; Up-Regulation | 2002 |
Effect of BU98008, an imidazoline1-binding site ligand, on body temperature in mice.
Topics: Animals; Benzofurans; Binding Sites; Body Temperature; Dose-Response Relationship, Drug; Idazoxan; Imidazoles; Imidazoline Receptors; Isoquinolines; Ligands; Male; Mice; Receptors, Drug | 2005 |