Page last updated: 2024-09-03

ethoxyidazoxan and clonidine

ethoxyidazoxan has been researched along with clonidine in 4 studies

Compound Research Comparison

Studies
(ethoxyidazoxan)
Trials
(ethoxyidazoxan)
Recent Studies (post-2010)
(ethoxyidazoxan)
Studies
(clonidine)
Trials
(clonidine)
Recent Studies (post-2010) (clonidine)
142013,6922,0441,394

Protein Interaction Comparison

ProteinTaxonomyethoxyidazoxan (IC50)clonidine (IC50)
Alpha-2A adrenergic receptorHomo sapiens (human)0.101
Alpha-2B adrenergic receptorHomo sapiens (human)0.0353
Alpha-2C adrenergic receptorHomo sapiens (human)0.0115
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)5.365
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)0.0173
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)0.0173
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)0.0173
Alpha-1D adrenergic receptorHomo sapiens (human)1.21
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)5.365
Alpha-2A adrenergic receptorBos taurus (cattle)0.002
NischarinRattus norvegicus (Norway rat)0.3662

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Convents, A; De Backer, JP; De Keyser, J; De Vos, H; Vauquelin, G1
Hussain, JF; Kendall, DA; Pinthong, D; Wilson, VG1
Mason, R; Mundey, MK; Wilson, VG1
Colpaert, FC; Pauwels, PJ1

Other Studies

4 other study(ies) available for ethoxyidazoxan and clonidine

ArticleYear
Identification of alpha 2 adrenoceptors in the human nucleus olivarius by radioligand binding.
    Progress in histochemistry and cytochemistry, 1992, Volume: 26, Issue:1-4

    Topics: Adrenergic alpha-Agonists; Aged; Binding, Competitive; Brain Chemistry; Clonidine; Dioxanes; Epinephrine; Humans; Idazoxan; Middle Aged; Olivary Nucleus; Radioligand Assay; Receptors, Adrenergic, alpha

1992
Comparison of the interaction of agmatine and crude methanolic extracts of bovine lung and brain with alpha 2-adrenoceptor binding sites.
    British journal of pharmacology, 1995, Volume: 115, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Agmatine; Animals; Binding, Competitive; Brimonidine Tartrate; Cattle; Cerebral Cortex; Clonidine; Dioxanes; Idazoxan; Imidazoles; Lung; Methanol; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Yohimbine

1995
Selective potentiation by ouabain of naloxone-induced withdrawal contractions of isolated guinea-pig ileum following acute exposure to morphine.
    British journal of pharmacology, 1998, Volume: 124, Issue:5

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Carbachol; Clonidine; Drug Synergism; Electric Stimulation; Enzyme Inhibitors; Guinea Pigs; Idazoxan; Ileum; In Vitro Techniques; Male; Morphine; Morphine Dependence; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Naloxone; Narcotic Antagonists; Ouabain; Receptors, Adrenergic, alpha-2; Sodium-Potassium-Exchanging ATPase; Substance Withdrawal Syndrome

1998
Partial to complete antagonism by putative antagonists at the wild-type alpha(2C)-adrenoceptor based on kinetic analyses of agonist:antagonist interactions.
    British journal of pharmacology, 2000, Volume: 131, Issue:7

    Topics: Adrenergic Agonists; Adrenergic Antagonists; Animals; Azepines; Brimonidine Tartrate; Calcium; CHO Cells; Clonidine; Cricetinae; DNA, Recombinant; Dose-Response Relationship, Drug; Drug Interactions; Epinephrine; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; Heterotrimeric GTP-Binding Proteins; Idazoxan; Kinetics; Medetomidine; Mice; Oxymetazoline; Quinoxalines; Rats; Receptors, Adrenergic, alpha-2; Recombinant Fusion Proteins; Transfection

2000