ethosuximide and gamma-aminobutyric acid

ethosuximide has been researched along with gamma-aminobutyric acid in 32 studies

Research

Studies (32)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (15.63)	18.7374
1990's	7 (21.88)	18.2507
2000's	14 (43.75)	29.6817
2010's	4 (12.50)	24.3611
2020's	2 (6.25)	2.80

Authors

Authors	Studies
Mori, Y; Nakamura, J; Sasaki, H; Shibasaki, J	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Coulter, DA; Huguenard, JR; Prince, DA	2
Chweh, AY; Lin-Michell, E; Swinyard, EA	1
Macdonald, RL; McLean, MJ	1
Geber, J; Gjuris, V; Mihoković, S; Tucan-Foretić, M	1
Lascelles, PT; Patsalos, PN	1
Barnes, DM; Dichter, MA	1
Hekster, YA; Keyser, A; Lammers, MW; Meinardi, H; Renier, WO; van Lier, H; Wijsman, DJ	1
Bernasconi, R; Bittiger, H; De Barry, J; Marescaux, C; Mathivet, P	1
Hechler, V; Maitre, M; Ratomponirina, C	1
Anderson, GD	1
Desiena, G; Lensu, S; Malmberg-Aiello, P; Tuomisto, L	1
Rekling, JC	1
Posner, E	4
Jevtovic-Todorovic, V; Rastogi, AJ; Todorovic, SM	1
Hartings, JA; Lu, XM; Moreton, JE; Tortella, FC; Williams, AJ	1
Papp, Z; Török, L	1
Eriksson, K; Keränen, T; Rainesalo, S; Saransaari, P	1
Aypak, C; Gören, MZ; Küçükibrahimoğlu, E; Onat, FY; Ozkaynakçi, AE; Terzioğlu, B	1
Bautista, CC; Chen, RW; Dave, JR; Hartings, JA; Lu, XC; Tortella, FC; Williams, AJ	1
Mula, M	1
Greenhill, SD; Jones, RS; Massey, PV; Morgan, NH; Woodhall, GL	1
Corrales, A; Flórez, J; García, S; Martínez, P; Martínez-Cué, C; Rueda, N; Sharma, A; Vidal, V	1
Booth, R; Kim, H	1
Bastin, ML; Cook, AM; Oyler, DR; Smetana, KS	1
Czuczwar, SJ; Krzyżanowski, M; Świąder, K; Świąder, MJ; Wróbel, A; Zakrocka, I; Łuszczki, JJ	1
Bahlo, M; Bello-Espinosa, LE; Bennett, MF; Berkovic, SF; Buchhalter, J; Chan, EK; D'Alfonso, S; Dabscheck, G; Damiano, JA; Grinton, BE; Hildebrand, MS; Myers, KA; Sadleir, LG; Scheffer, IE; Schneider, AL	1

Reviews

7 review(s) available for ethosuximide and gamma-aminobutyric acid

Article	Year
A mechanistic approach to antiepileptic drug interactions. The Annals of pharmacotherapy, 1998, Volume: 32, Issue:5 Topics: Acetates; Amines; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cyclohexanecarboxylic Acids; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Ethosuximide; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Glucuronosyltransferase; Humans; Lamotrigine; Mixed Function Oxygenases; Nipecotic Acids; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Tiagabine; Topiramate; Triazines; Valproic Acid; Vigabatrin	1998
Absence seizures in children. Clinical evidence, 2002, Issue:8 Topics: Acetates; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy, Absence; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines; Valproic Acid	2002
Absence seizures in children. Clinical evidence, 2003, Issue:10 Topics: Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy, Absence; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines; Valproic Acid	2003
Absence seizures in children. Clinical evidence, 2004, Issue:11 Topics: Adolescent; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy, Absence; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines; Valproic Acid	2004
Absence seizures in children. Clinical evidence, 2005, Issue:13 Topics: Adolescent; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Epilepsy, Absence; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines; Valproic Acid	2005
New antiepileptic drugs: molecular targets. Central nervous system agents in medicinal chemistry, 2009, Volume: 9, Issue:2 Topics: Action Potentials; Animals; Anticonvulsants; Barbiturates; Carbamazepine; Clinical Trials as Topic; Drug Evaluation, Preclinical; Drug Monitoring; Electroshock; Epilepsy; Ethosuximide; gamma-Aminobutyric Acid; Humans; Molecular Structure; Neurotransmitter Transport Proteins; Phenytoin; Randomized Controlled Trials as Topic; Receptors, N-Methyl-D-Aspartate; Seizures; Structure-Activity Relationship; Synaptic Transmission; Treatment Outcome; Valproic Acid	2009
Antiepileptic dosing for critically ill adult patients receiving renal replacement therapy. Journal of critical care, 2016, Volume: 36 Topics: Acetamides; Acute Kidney Injury; Amines; Anticonvulsants; Carbamates; Critical Illness; Cyclohexanecarboxylic Acids; Dibenzazepines; Dose-Response Relationship, Drug; Ethosuximide; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lacosamide; Lamotrigine; Levetiracetam; Phenobarbital; Phenylcarbamates; Phenylenediamines; Phenytoin; Piracetam; Propylene Glycols; Renal Dialysis; Renal Replacement Therapy; Seizures; Topiramate; Triazines; Valproic Acid; Zonisamide	2016

Other Studies

25 other study(ies) available for ethosuximide and gamma-aminobutyric acid

Article	Year
Synthesis and anticonvulsant activity of 1-acyl-2-pyrrolidinone derivatives. Journal of medicinal chemistry, 1991, Volume: 34, Issue:2 Topics: Animals; Anticonvulsants; Chemical Phenomena; Chemistry; gamma-Aminobutyric Acid; Male; Mice; Pyrrolidinones; Rats; Receptors, GABA-A; Seizures; Sleep; Structure-Activity Relationship	1991
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Differential effects of petit mal anticonvulsants and convulsants on thalamic neurones: GABA current blockade. British journal of pharmacology, 1990, Volume: 100, Issue:4 Topics: Animals; Anticonvulsants; Bicuculline; Convulsants; Epilepsy, Absence; Ethosuximide; gamma-Aminobutyric Acid; In Vitro Techniques; Iontophoresis; Neurons; Pentylenetetrazole; Picrotoxin; Rats; Succinimides; Thalamus	1990
Differential effects of petit mal anticonvulsants and convulsants on thalamic neurones: calcium current reduction. British journal of pharmacology, 1990, Volume: 100, Issue:4 Topics: Animals; Anticonvulsants; Calcium Channels; Convulsants; Epilepsy, Absence; Ethosuximide; gamma-Aminobutyric Acid; Neurons; Pentylenetetrazole; Rats; Structure-Activity Relationship; Succinimides; Thalamus	1990
Effect of ethosuximide alone and in combination with gamma-aminobutyric acid receptor agonists on brain gamma-aminobutyric acid concentration, anticonvulsant activity and neurotoxicity in mice. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 237, Issue:2 Topics: Animals; Brain Chemistry; Ethosuximide; gamma-Aminobutyric Acid; Isoxazoles; Male; Mice; Mice, Inbred Strains; Nervous System; Pentylenetetrazole; Receptors, GABA-A; Seizures	1986
Sodium valproate, but not ethosuximide, produces use- and voltage-dependent limitation of high frequency repetitive firing of action potentials of mouse central neurons in cell culture. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 237, Issue:3 Topics: Action Potentials; Animals; Carbamazepine; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Electric Stimulation; Ethosuximide; gamma-Aminobutyric Acid; Magnesium; Mice; Neurons; Phenytoin; Seizures; Sodium; Spinal Cord; Valproic Acid	1986
Facilitation of GABA-ergic transmission by ethosuximide. Acta medica Iugoslavica, 1984, Volume: 38, Issue:5 Topics: Animals; Cats; Ethosuximide; Female; gamma-Aminobutyric Acid; Male; Reflex, Monosynaptic; Synaptic Transmission	1984
Changes in regional brain levels of amino acid putative neurotransmitters after prolonged treatment with the anticonvulsant drugs diphenylhydantoin, phenobarbitone, sodium valproate, ethosuximide, and sulthiame in the rat. Journal of neurochemistry, 1981, Volume: 36, Issue:2 Topics: Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Brain; Ethosuximide; gamma-Aminobutyric Acid; Glutamates; Male; Neurotransmitter Agents; Organ Specificity; Phenobarbital; Phenytoin; Rats; Taurine; Thiazines; Valproic Acid	1981
Effects of ethosuximide and tetramethylsuccinimide on cultured cortical neurons. Neurology, 1984, Volume: 34, Issue:5 Topics: Animals; Anticonvulsants; Ethosuximide; gamma-Aminobutyric Acid; Membrane Potentials; Neuromuscular Junction; Picrotoxin; Receptors, Neurotransmitter; Rodentia; Succinimides; Synaptic Transmission	1984
Epilepsy treatment in The Netherlands. Comparison of matched groups of two medical centres. Acta neurologica Scandinavica, 1994, Volume: 89, Issue:6 Topics: Adolescent; Adult; Carbamazepine; Diazepam; Epilepsy; Ethosuximide; Female; gamma-Aminobutyric Acid; Humans; Male; Netherlands; Phenobarbital; Phenytoin; Primidone; Quality of Health Care; Statistics, Nonparametric; Treatment Outcome; Valproic Acid; Vigabatrin	1994
Binding characteristics of gamma-hydroxybutyric acid as a weak but selective GABAB receptor agonist. European journal of pharmacology, 1997, Feb-19, Volume: 321, Issue:1 Topics: Animals; Anticonvulsants; Baclofen; Binding, Competitive; Brain Chemistry; Ethosuximide; GABA Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Guanylyl Imidodiphosphate; In Vitro Techniques; Male; Organophosphorus Compounds; Radioligand Assay; Rats; Rats, Wistar; Receptors, GABA-B; Sodium Oxybate; Valproic Acid	1997
gamma-Hydroxybutyrate conversion into GABA induces displacement of GABAB binding that is blocked by valproate and ethosuximide. The Journal of pharmacology and experimental therapeutics, 1997, Volume: 281, Issue:2 Topics: 4-Aminobutyrate Transaminase; Animals; Binding Sites; Brain; Enzyme Inhibitors; Ethosuximide; gamma-Aminobutyric Acid; Hydroxybutyrate Dehydrogenase; In Vitro Techniques; Male; Rats; Rats, Wistar; Sodium Oxybate; Valproic Acid	1997
Effect of some antiepileptic drugs on brain histaminergic systems in the rat. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2002, Volume: 51 Suppl 1 Topics: Acetates; Amines; Animals; Anticonvulsants; Brain Chemistry; Cyclohexanecarboxylic Acids; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Histamine; Methylhistamines; Phenytoin; Rats; Rats, Wistar	2002
Neuroprotective effects of anticonvulsants in rat hippocampal slice cultures exposed to oxygen/glucose deprivation. Neuroscience letters, 2003, Jan-02, Volume: 335, Issue:3 Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamates; Carbamazepine; Cell Death; Cells, Cultured; Chlordiazepoxide; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Ethosuximide; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Glucose; Hippocampus; Hypoxia; Ischemia; Lamotrigine; Levetiracetam; Midazolam; Neurons; Neuroprotective Agents; Nipecotic Acids; Oxcarbazepine; Phenobarbital; Phenylcarbamates; Phenylenediamines; Phenytoin; Piracetam; Propylene Glycols; Rats; Rats, Wistar; Tiagabine; Triazines; Valproic Acid	2003
Potent analgesic effects of anticonvulsants on peripheral thermal nociception in rats. British journal of pharmacology, 2003, Volume: 140, Issue:2 Topics: Acetates; Amines; Analgesics; Animals; Anticonvulsants; Calcium Channel Blockers; Carbamazepine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Ethosuximide; Female; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Hyperalgesia; Neurons, Afferent; Pain Measurement; Peripheral Nervous System Diseases; Phenytoin; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers	2003
Antiepileptic drug treatment of nonconvulsive seizures induced by experimental focal brain ischemia. The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:1 Topics: Amines; Animals; Anticonvulsants; Brain Infarction; Brain Injuries; Brain Ischemia; Cyclohexanecarboxylic Acids; Disease Models, Animal; Electroencephalography; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Male; Rats; Rats, Sprague-Dawley; Seizures	2004
[Anticonvulsant hypersensitivity syndrome]. Orvosi hetilap, 2004, Aug-08, Volume: 145, Issue:32 Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Eruptions; Drug Hypersensitivity; Ethosuximide; Fever; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lymphatic Diseases; Phenobarbital; Phenytoin; Syndrome; Triazines; Valproic Acid	2004
Uptake of GABA and activity of GABA transaminase in blood platelets from children with absence epilepsy. Neurochemical research, 2004, Volume: 29, Issue:10 Topics: 4-Aminobutyrate Transaminase; Adolescent; Blood Platelets; Child; Child, Preschool; Dose-Response Relationship, Drug; Enzyme Activation; Epilepsy, Absence; Ethosuximide; Female; gamma-Aminobutyric Acid; Humans; Male	2004
The effects of ethosuximide on amino acids in genetic absence epilepsy rat model. Journal of pharmacological sciences, 2006, Volume: 100, Issue:3 Topics: Animals; Anticonvulsants; Disease Models, Animal; Electroencephalography; Epilepsy, Absence; Ethosuximide; gamma-Aminobutyric Acid; Glutamic Acid; Microdialysis; Motor Cortex; Rats; Rats, Wistar; Time Factors; Ventral Thalamic Nuclei	2006
Evaluation of gabapentin and ethosuximide for treatment of acute nonconvulsive seizures following ischemic brain injury in rats. The Journal of pharmacology and experimental therapeutics, 2006, Volume: 318, Issue:3 Topics: Acute Disease; Amines; Animals; Brain Ischemia; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Electroencephalography; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Seizures	2006
Ethosuximide modifies network excitability in the rat entorhinal cortex via an increase in GABA release. Neuropharmacology, 2012, Volume: 62, Issue:2 Topics: Animals; Anticonvulsants; Entorhinal Cortex; Ethosuximide; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Male; Membrane Potentials; Nerve Net; Neural Inhibition; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Synapses; Synaptic Transmission	2012
Lack of behavioral and cognitive effects of chronic ethosuximide and gabapentin treatment in the Ts65Dn mouse model of Down syndrome. Neuroscience, 2012, Sep-18, Volume: 220 Topics: Amines; Animals; Anticonvulsants; Behavior, Animal; Cognition; Cyclohexanecarboxylic Acids; Disease Models, Animal; Down Syndrome; Ethosuximide; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Gabapentin; gamma-Aminobutyric Acid; Male; Mice	2012
Permeability analysis of neuroactive drugs through a dynamic microfluidic in vitro blood-brain barrier model. Annals of biomedical engineering, 2014, Volume: 42, Issue:12 Topics: Amines; Animals; Benzazepines; Biological Transport; Blood-Brain Barrier; Cell Survival; Cells, Cultured; Coculture Techniques; Cyclohexanecarboxylic Acids; Endothelial Cells; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Indoles; L-Lactate Dehydrogenase; Mice; Microfluidic Analytical Techniques; Neuroglia; Permeability; Piperidines; Pyrroles; Quinoxalines; Rats; Rats, Sprague-Dawley; Sertraline; Sunitinib; Tetrahydronaphthalenes; Valine; Varenicline	2014
Long-term vigabatrin treatment modifies pentylenetetrazole-induced seizures in mice: focused on GABA brain concentration. Pharmacological reports : PR, 2020, Volume: 72, Issue:2 Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Brain; Clonazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ethosuximide; gamma-Aminobutyric Acid; Mice; Pentylenetetrazole; Seizures; Time Factors; Valproic Acid; Vigabatrin	2020
Contribution of rare genetic variants to drug response in absence epilepsy. Epilepsy research, 2021, Volume: 170 Topics: Anticonvulsants; Epilepsy, Absence; Ethosuximide; gamma-Aminobutyric Acid; Humans; Pharmaceutical Preparations; Valproic Acid	2021