ethosuximide and gabapentin

ethosuximide has been researched along with gabapentin in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.85)18.2507
2000's16 (61.54)29.6817
2010's8 (30.77)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Bruno-Blanch, L; Gálvez, J; García-Domenech, R1
Jolivette, LJ; Ward, KW1
Jolivette, LJ; Nagilla, R; Ward, KW1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Kavya, R; Nageswari, Y; Ragavendran, JV; Sreevatsan, N; Sriram, D; Stables, J; Vanitha, K; Yogeeswari, P1
Brenneman, D; Cuyckens, F; Finley, MF; Herb, M; Huang, Y; Iannucci, R; Klein, B; Leclercq, L; Liu, Y; Lubin, ML; Malatynska, E; Maryanoff, BE; McComsey, DF; Milewski, ME; Parker, MH; Qin, N; Reitz, AB; Smith-Swintosky, VL; White, HS1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Brenneman, DE; Finley, MF; Herb, M; Klein, BD; Liu, Y; Lubin, ML; Malatynska, E; Maryanoff, BE; McComsey, DF; Milewski, ME; Parker, MH; Qin, N; Reitz, AB; Smith-Swintosky, VL; White, HS; Wilcox, KS1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Anderson, GD1
Desiena, G; Lensu, S; Malmberg-Aiello, P; Tuomisto, L1
Rekling, JC1
Posner, E4
Jevtovic-Todorovic, V; Rastogi, AJ; Todorovic, SM1
Hartings, JA; Lu, XM; Moreton, JE; Tortella, FC; Williams, AJ1
Papp, Z; Török, L1
Bautista, CC; Chen, RW; Dave, JR; Hartings, JA; Lu, XC; Tortella, FC; Williams, AJ1
Corrales, A; Flórez, J; García, S; Martínez, P; Martínez-Cué, C; Rueda, N; Sharma, A; Vidal, V1
Booth, R; Kim, H1
Bastin, ML; Cook, AM; Oyler, DR; Smetana, KS1
Battino, D; Bromley, R; Kochen, S; Meador, KJ; Pennell, PB; Thomas, SV; Tomson, T1

Reviews

8 review(s) available for ethosuximide and gabapentin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
A mechanistic approach to antiepileptic drug interactions.
    The Annals of pharmacotherapy, 1998, Volume: 32, Issue:5

    Topics: Acetates; Amines; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cyclohexanecarboxylic Acids; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Ethosuximide; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Glucuronosyltransferase; Humans; Lamotrigine; Mixed Function Oxygenases; Nipecotic Acids; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Tiagabine; Topiramate; Triazines; Valproic Acid; Vigabatrin

1998
Absence seizures in children.
    Clinical evidence, 2002, Issue:8

    Topics: Acetates; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy, Absence; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines; Valproic Acid

2002
Absence seizures in children.
    Clinical evidence, 2003, Issue:10

    Topics: Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy, Absence; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines; Valproic Acid

2003
Absence seizures in children.
    Clinical evidence, 2004, Issue:11

    Topics: Adolescent; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy, Absence; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines; Valproic Acid

2004
Absence seizures in children.
    Clinical evidence, 2005, Issue:13

    Topics: Adolescent; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Epilepsy, Absence; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines; Valproic Acid

2005
Antiepileptic dosing for critically ill adult patients receiving renal replacement therapy.
    Journal of critical care, 2016, Volume: 36

    Topics: Acetamides; Acute Kidney Injury; Amines; Anticonvulsants; Carbamates; Critical Illness; Cyclohexanecarboxylic Acids; Dibenzazepines; Dose-Response Relationship, Drug; Ethosuximide; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lacosamide; Lamotrigine; Levetiracetam; Phenobarbital; Phenylcarbamates; Phenylenediamines; Phenytoin; Piracetam; Propylene Glycols; Renal Dialysis; Renal Replacement Therapy; Seizures; Topiramate; Triazines; Valproic Acid; Zonisamide

2016
Breastfeeding while on treatment with antiseizure medications: a systematic review from the ILAE Women Task Force
    Epileptic disorders : international epilepsy journal with videotape, 2022, 12-01, Volume: 24, Issue:6

    Topics: Breast Feeding; Cannabidiol; Carbamazepine; Child; Clobazam; Clonazepam; Epilepsy; Ethosuximide; Everolimus; Felbamate; Female; Fenfluramine; Gabapentin; Humans; Infant; Lacosamide; Lamotrigine; Levetiracetam; Oxcarbazepine; Phenobarbital; Phenytoin; Prospective Studies; Tiagabine; Topiramate; Valproic Acid; Vigabatrin; Zonisamide

2022

Other Studies

18 other study(ies) available for ethosuximide and gabapentin

ArticleYear
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship

2003
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7

    Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution

2005
Comparative evaluation of oral systemic exposure of 56 xenobiotics in rat, dog, monkey and human.
    Xenobiotica; the fate of foreign compounds in biological systems, 2005, Volume: 35, Issue:2

    Topics: Administration, Oral; Animals; Area Under Curve; Dogs; Haplorhini; Humans; Models, Statistical; Rats; Software; Species Specificity; Xenobiotics

2005
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Discovery of 4-aminobutyric acid derivatives possessing anticonvulsant and antinociceptive activities: a hybrid pharmacophore approach.
    Journal of medicinal chemistry, 2007, May-17, Volume: 50, Issue:10

    Topics: Analgesics; Animals; Anticonvulsants; Disease Models, Animal; gamma-Aminobutyric Acid; Hyperalgesia; Mice; Pain; Pain Measurement; Peripheral Nerve Injuries; Peripheral Nervous System Diseases; Rats; Semicarbazones; Structure-Activity Relationship; Touch

2007
Novel, broad-spectrum anticonvulsants containing a sulfamide group: advancement of N-((benzo[b]thien-3-yl)methyl)sulfamide (JNJ-26990990) into human clinical studies.
    Journal of medicinal chemistry, 2009, Dec-10, Volume: 52, Issue:23

    Topics: Amides; Animals; Anticonvulsants; Carbonic Anhydrase II; Cell Line; Clinical Trials as Topic; Drug Evaluation, Preclinical; Female; Humans; Male; Mice; Rats; Sulfonamides; Thiophenes

2009
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Novel, broad-spectrum anticonvulsants containing a sulfamide group: pharmacological properties of (S)-N-[(6-chloro-2,3-dihydrobenzo[1,4]dioxin-2-yl)methyl]sulfamide (JNJ-26489112).
    Journal of medicinal chemistry, 2013, Nov-27, Volume: 56, Issue:22

    Topics: Absorption; Amides; Animals; Anticonvulsants; Dioxanes; Dogs; Drug Evaluation, Preclinical; Drug Resistance; Epilepsy; Female; Humans; Male; Mice; Rats; Sulfonamides

2013
Effect of some antiepileptic drugs on brain histaminergic systems in the rat.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2002, Volume: 51 Suppl 1

    Topics: Acetates; Amines; Animals; Anticonvulsants; Brain Chemistry; Cyclohexanecarboxylic Acids; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Histamine; Methylhistamines; Phenytoin; Rats; Rats, Wistar

2002
Neuroprotective effects of anticonvulsants in rat hippocampal slice cultures exposed to oxygen/glucose deprivation.
    Neuroscience letters, 2003, Jan-02, Volume: 335, Issue:3

    Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamates; Carbamazepine; Cell Death; Cells, Cultured; Chlordiazepoxide; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Ethosuximide; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Glucose; Hippocampus; Hypoxia; Ischemia; Lamotrigine; Levetiracetam; Midazolam; Neurons; Neuroprotective Agents; Nipecotic Acids; Oxcarbazepine; Phenobarbital; Phenylcarbamates; Phenylenediamines; Phenytoin; Piracetam; Propylene Glycols; Rats; Rats, Wistar; Tiagabine; Triazines; Valproic Acid

2003
Potent analgesic effects of anticonvulsants on peripheral thermal nociception in rats.
    British journal of pharmacology, 2003, Volume: 140, Issue:2

    Topics: Acetates; Amines; Analgesics; Animals; Anticonvulsants; Calcium Channel Blockers; Carbamazepine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Ethosuximide; Female; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Hyperalgesia; Neurons, Afferent; Pain Measurement; Peripheral Nervous System Diseases; Phenytoin; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers

2003
Antiepileptic drug treatment of nonconvulsive seizures induced by experimental focal brain ischemia.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:1

    Topics: Amines; Animals; Anticonvulsants; Brain Infarction; Brain Injuries; Brain Ischemia; Cyclohexanecarboxylic Acids; Disease Models, Animal; Electroencephalography; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Male; Rats; Rats, Sprague-Dawley; Seizures

2004
[Anticonvulsant hypersensitivity syndrome].
    Orvosi hetilap, 2004, Aug-08, Volume: 145, Issue:32

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Eruptions; Drug Hypersensitivity; Ethosuximide; Fever; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lymphatic Diseases; Phenobarbital; Phenytoin; Syndrome; Triazines; Valproic Acid

2004
Evaluation of gabapentin and ethosuximide for treatment of acute nonconvulsive seizures following ischemic brain injury in rats.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 318, Issue:3

    Topics: Acute Disease; Amines; Animals; Brain Ischemia; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Electroencephalography; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Seizures

2006
Lack of behavioral and cognitive effects of chronic ethosuximide and gabapentin treatment in the Ts65Dn mouse model of Down syndrome.
    Neuroscience, 2012, Sep-18, Volume: 220

    Topics: Amines; Animals; Anticonvulsants; Behavior, Animal; Cognition; Cyclohexanecarboxylic Acids; Disease Models, Animal; Down Syndrome; Ethosuximide; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Gabapentin; gamma-Aminobutyric Acid; Male; Mice

2012
Permeability analysis of neuroactive drugs through a dynamic microfluidic in vitro blood-brain barrier model.
    Annals of biomedical engineering, 2014, Volume: 42, Issue:12

    Topics: Amines; Animals; Benzazepines; Biological Transport; Blood-Brain Barrier; Cell Survival; Cells, Cultured; Coculture Techniques; Cyclohexanecarboxylic Acids; Endothelial Cells; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Indoles; L-Lactate Dehydrogenase; Mice; Microfluidic Analytical Techniques; Neuroglia; Permeability; Piperidines; Pyrroles; Quinoxalines; Rats; Rats, Sprague-Dawley; Sertraline; Sunitinib; Tetrahydronaphthalenes; Valine; Varenicline

2014